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Barry Nelkin

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Tikva Dadon; Douglas W Ball; Barry D Nelkin
Misidentification of putative medullary thyroid cancer cell lines RO-H85-1 and RO-D81-1.
Nishant Agrawal; Chetan Bettegowda; Sheetal Bhan; Justin Bishop; Timothy Chan; Henning Dralle; James A Fagin; Ronald A Ghossein; Allen S Ho; Ralph Hruban; Yuchen Jiao; ZUBAIR KHAN; Kenneth W Kinzler; Rebecca Leary; Luc G T Morris; Barry D Nelkin; Nickolas Papadopoulos; Nicholas J Roberts; Bruce Robinson; Mark Sausen; Rodrigo A Toledo; Sergio P A Toledo; Ralph P Tufano; Victor E Velculescu; Bert Vogelstein; William H Westra; Laura D Wood; Douglas W Ball
Exomic sequencing of medullary thyroid cancer reveals dominant and mutually exclusive oncogenic mutations in RET and RAS.
Ning Jin; Barry D Nelkin; David M Rosen; Tianyun Jiang; Douglas W Ball
Synergistic action of a RAF inhibitor and a dual PI3K/mTOR inhibitor in thyroid cancer.

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2013: Tikva Dadon; Douglas W Ball; Barry D Nelkin
Misidentification of putative medullary thyroid cancer cell lines RO-H85-1 and RO-D81-1.
The Journal of clinical endocrinology and metabolism 2013;98(3):954-5.
2013: Nishant Agrawal; Chetan Bettegowda; Sheetal Bhan; Justin Bishop; Timothy Chan; Henning Dralle; James A Fagin; Ronald A Ghossein; Allen S Ho; Ralph Hruban; Yuchen Jiao; ZUBAIR KHAN; Kenneth W Kinzler; Rebecca Leary; Luc G T Morris; Barry D Nelkin; Nickolas Papadopoulos; Nicholas J Roberts; Bruce Robinson; Mark Sausen; Rodrigo A Toledo; Sergio P A Toledo; Ralph P Tufano; Victor E Velculescu; Bert Vogelstein; William H Westra; Laura D Wood; Douglas W Ball
Exomic sequencing of medullary thyroid cancer reveals dominant and mutually exclusive oncogenic mutations in RET and RAS.
The Journal of clinical endocrinology and metabolism 2013;98(2):E364-9.
2011: Ning Jin; Barry D Nelkin; David M Rosen; Tianyun Jiang; Douglas W Ball
Synergistic action of a RAF inhibitor and a dual PI3K/mTOR inhibitor in thyroid cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(20):6482-9.
2011: Georg Feldmann; Volker Fendrich; Ignacio Garrido-Laguna; Manuel Hidalgo; Collins A Karikari; Anirban Maitra; William Matsui; Anjali Mishra; Hector Alvarez; Rajat Bannerji; Savita Bisht; Peter Brossart; Tikva Dadon; Niki A Ottenhof; RAJESH KUMAR NV; Zeshaan A Rasheed; Barry D Nelkin
Cyclin-dependent kinase inhibitor Dinaciclib (SCH727965) inhibits pancreatic cancer growth and progression in murine xenograft models.
Cancer biology & therapy 2011;12(7):598-609.
2010: Alvarez Hector; Elizabeth Montgomery; Collins A Karikari; Marcia Canto; Kerry Brandt Dunbar; JEAN WANG; Georg Feldmann; Seung-Mo Hong; Michael C Haffner; Alan K Meeker; Sacha J Holland; Jiaxin Yu; Thilo J Heckrodt; Jing Zhang; Pingyu Ding; Dane Goff; Rajinder Singh; Juan Carlos Roa; Arivusudar Marimuthu; Gregory J Riggins; James R Eshleman; Barry D Nelkin; Akhilesh Pandey; Anirban Maitra
The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma.
Cancer biology & therapy 2010;10(10):1009-18.
2010: Georg Feldmann; Anjali Mishra; Seung-Mo Hong; Savita Bisht; Christopher J Strock; Douglas W Ball; Michael Goggins; Anirban Maitra; Barry D Nelkin
Inhibiting the cyclin-dependent kinase CDK5 blocks pancreatic cancer formation and progression through the suppression of Ras-Ral signaling.
Cancer research 2010;70(11):4460-9.
2009: Ning Jin; Tianyun Jiang; D Marc Rosen; Barry D Nelkin; Douglas W Ball
Dual inhibition of mitogen-activated protein kinase kinase and mammalian target of rapamycin in differentiated and anaplastic thyroid cancer.
The Journal of clinical endocrinology and metabolism 2009;94(10):4107-12.
2009: Tianyun Jiang; Brendan J Collins; Ning Jin; DAVID WATKINS; Malcolm V Brock; William Matsui; Barry D Nelkin; Douglas W Ball
Achaete-scute complex homologue 1 regulates tumor-initiating capacity in human small cell lung cancer.
Cancer research 2009;69(3):845-54.
2007: Douglas W Ball; Ning Jin; D Marc Rosen; Alan P B Dackiw; David Sidransky; Michael M. Xing; Barry D Nelkin
Selective growth inhibition in BRAF mutant thyroid cancer by the mitogen-activated protein kinase kinase 1/2 inhibitor AZD6244.
The Journal of clinical endocrinology and metabolism 2007;92(12):4712-8.
2007: Igal Madar; Hayden T Ravert; Barry D Nelkin; Masroor Abro; Martin G Pomper; Robert F Dannals; J James Frost
Characterization of membrane potential-dependent uptake of the novel PET tracer 18F-fluorobenzyl triphenylphosphonium cation.
European journal of nuclear medicine and molecular imaging 2007;34(12):2057-65.
2006: Matthias Sommer; Nina Poliak; Sunil Upadhyay; Edward Ratovitski; Barry D Nelkin; Lawrence A Donehower; David Sidransky
DeltaNp63alpha overexpression induces downregulation of Sirt1 and an accelerated aging phenotype in the mouse.
Cell cycle (Georgetown, Tex.) 2006;5(17):2005-11.
2006: Christopher J Strock; Jong-In Park; Eric K Nakakura; G Steven Bova; John T Isaacs; Douglas W Ball; Barry D Nelkin
Cyclin-dependent kinase 5 activity controls cell motility and metastatic potential of prostate cancer cells.
Cancer research 2006;66(15):7509-15.
2006: Istvan Arany; Judit Megyesi; Barry D Nelkin; Robert L Safirstein
STAT3 attenuates EGFR-mediated ERK activation and cell survival during oxidant stress in mouse proximal tubular cells.
Kidney international 2006;70(4):669-74.
2006: Christopher J Strock; Jong-In Park; D Marc Rosen; Bruce Ruggeri; Samuel R Denmeade; Douglas W Ball; Barry D Nelkin
Activity of irinotecan and the tyrosine kinase inhibitor CEP-751 in medullary thyroid cancer.
The Journal of clinical endocrinology and metabolism 2006;91(1):79-84.
2005: Eric K Nakakura; Virote Sriuranpong; Muthusamy Kunnimalaiyaan; Edward C Hsiao; Kornel E Schuebel; Michael W Borges; Ning Jin; Brendan J Collins; Barry D Nelkin; Herbert Chen; Douglas W Ball
Regulation of neuroendocrine differentiation in gastrointestinal carcinoid tumor cells by notch signaling.
The Journal of clinical endocrinology and metabolism 2005;90(7):4350-6.
2005: Eun-Joo Kim; Jong-In Park; Barry D Nelkin
IFI16 is an essential mediator of growth inhibition, but not differentiation, induced by the leukemia inhibitory factor/JAK/STAT pathway in medullary thyroid carcinoma cells.
The Journal of biological chemistry 2005;280(6):4913-20.
2005: Jong-In Park; Christopher J Strock; Douglas W Ball; Barry D Nelkin
Interleukin-1beta can mediate growth arrest and differentiation via the leukemia inhibitory factor/JAK/STAT pathway in medullary thyroid carcinoma cells.
Cytokine 2005;29(3):125-34.
2005: Jong-In Park; James F Powers; Arthur S Tischler; Christopher J Strock; Douglas W Ball; Barry D Nelkin
GDNF-induced leukemia inhibitory factor can mediate differentiation via the MEK/ERK pathway in pheochromocytoma cells derived from nf1-heterozygous knockout mice.
Experimental cell research 2005;303(1):79-88.
2003: Christopher J Strock; Jong-In Park; Mark Rosen; Craig Dionne; Bruce Ruggeri; Susan Jones-Bolin; Samuel R Denmeade; Douglas W Ball; Barry D Nelkin
CEP-701 and CEP-751 inhibit constitutively activated RET tyrosine kinase activity and block medullary thyroid carcinoma cell growth.
Cancer research 2003;63(17):5559-63.
2003: Virote Sriuranpong; Jong-In Park; Panomwat Amornphimoltham; Vyomesh Patel; Barry D Nelkin; J Silvio Gutkind
Epidermal growth factor receptor-independent constitutive activation of STAT3 in head and neck squamous cell carcinoma is mediated by the autocrine/paracrine stimulation of the interleukin 6/gp130 cytokine system.
Cancer research 2003;63(11):2948-56.
2003: Jong-In Park; Christopher J Strock; Douglas W Ball; Barry D Nelkin
The Ras/Raf/MEK/extracellular signal-regulated kinase pathway induces autocrine-paracrine growth inhibition via the leukemia inhibitory factor/JAK/STAT pathway.
Molecular and cellular biology 2003;23(2):543-54.
2003: Rajani Ravi; Barry D Nelkin
Assays for raf-1 kinase phosphorylation and activity in human small cell lung cancer cells.
Methods in molecular medicine 2003;74():201-10.
2002: Grant C Sellar; Karen P Watt; Li Li; Barry D Nelkin; Genevieve J Rabiasz; David J Porteous; John F Smyth; Hani Gabra
The homeobox gene BARX2 can modulate cisplatin sensitivity in human epithelial ovarian cancer.
International journal of oncology 2002;21(5):929-33.
2002: Virote Sriuranpong; Michael W Borges; Christopher L Strock; Eric K Nakakura; DAVID WATKINS; Christine M Blaumueller; Barry D Nelkin; Douglas W Ball
Notch signaling induces rapid degradation of achaete-scute homolog 1.
Molecular and cellular biology 2002;22(9):3129-39.
2001: Eric K Nakakura; DAVID WATKINS; Virote Sriuranpong; Michael W Borges; Barry D Nelkin; Douglas W Ball
Mammalian Scratch participates in neuronal differentiation in P19 embryonal carcinoma cells.
Brain research. Molecular brain research 2001;95(1-2):162-6.
2001: Grant C Sellar; Li Li; Karen P Watt; Barry D Nelkin; Genevieve J Rabiasz; Euan A Stronach; Eric P Miller; David J Porteous; John F Smyth; Hani Gabra
BARX2 induces cadherin 6 expression and is a functional suppressor of ovarian cancer progression.
Cancer research 2001;61(19):6977-81.
2001: Virote Sriuranpong; Michael W Borges; Rajani Ravi; D R Arnold; Barry D Nelkin; Stephen B Baylin; Douglas W Ball
Notch signaling induces cell cycle arrest in small cell lung cancer cells.
Cancer research 2001;61(7):3200-5.
2001: Eric K Nakakura; DAVID WATKINS; Kornel E Schuebel; Virote Sriuranpong; Michael W Borges; Barry D Nelkin; Douglas W Ball
Mammalian Scratch: a neural-specific Snail family transcriptional repressor.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(7):4010-5.
2001: Barry D Nelkin; Douglas W Ball
Combretastatin A-4 and doxorubicin combination treatment is effective in a preclinical model of human medullary thyroid carcinoma.
Oncology reports 2001;8(1):157-60.
2000: Hyo Chol Ha; A Thiagalingam; Barry D Nelkin; Robert A Casero
Reactive oxygen species are critical for the growth and differentiation of medullary thyroid carcinoma cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(9):3783-7.
2000: R Ilona Linnoila; B Zhao; Janet DeMayo; Barry D Nelkin; Stephen B Baylin; Francesco J DeMayo; Douglas W Ball
Constitutive achaete-scute homologue-1 promotes airway dysplasia and lung neuroendocrine tumors in transgenic mice.
Cancer research 2000;60(15):4005-9.
2000: A Krasner; L Wallace; A Thiagalingam; C Jones; Christoph Lengauer; L Minahan; Y Ma; L Kalikin; Andrew P Feinberg; Ethylin Jabs; A Tunnacliffe; Stephen B Baylin; Douglas W Ball; Barry D Nelkin
Cloning and chromosomal localization of the human BARX2 homeobox protein gene.
Gene 2000;250(1-2):171-80.
1999: L M McGregor; B K McCune; J R Graff; P R McDowell; Katharine E Romans; G D Yancopoulos; Douglas W Ball; Stephen B Baylin; Barry D Nelkin
Roles of trk family neurotrophin receptors in medullary thyroid carcinoma development and progression.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(8):4540-5.
1999: Rajani Ravi; A Thiagalingam; E Weber; M McMahon; Barry D Nelkin; M Mabry
Raf-1 causes growth suppression and alteration of neuroendocrine markers in DMS53 human small-cell lung cancer cells.
American journal of respiratory cell and molecular biology 1999;20(4):543-9.
1999: E Weber; Rajani Ravi; Erik S Knudsen; JR Williams; Larry E Dillehay; Barry D Nelkin; Gregory P Kalemkerian; James R Feramisco; M Mabry
Retinoic acid-mediated growth inhibition of small cell lung cancer cells is associated with reduced myc and increased p27Kip1 expression.
International journal of cancer. Journal international du cancer 1999;80(6):935-43.
1999: Rajani Ravi; M McMahon; Z Yangang; JR Williams; Larry E Dillehay; Barry D Nelkin; M Mabry
Raf-1-induced cell cycle arrest in LNCaP human prostate cancer cells.
Journal of cellular biochemistry 1999;72(4):458-69.
1998: Yanlin Wang; L Xiao; A Thiagalingam; Barry D Nelkin; Robert A Casero
The identification of a cis-element and a trans-acting factor involved in the response to polyamines and polyamine analogues in the regulation of the human spermidine/spermine N1-acetyltransferase gene transcription.
The Journal of biological chemistry 1998;273(51):34623-30.
1998: Eleanor B Carson-Walter; D P Smith; bruce ponder; Stephen B Baylin; Barry D Nelkin
Post-transcriptional silencing of RET occurs, but is not required, during raf-1 mediated differentiation of medullary thyroid carcinoma cells.
Oncogene 1998;17(3):367-76.
1998: Rajani Ravi; F M Scott; F Cuttitta; E Weber; Gregory P Kalemkerian; Barry D Nelkin; M Mabry
Induction of gastrin releasing peptide by all-trans retinoic acid in small cell lung cancer cells.
Oncology reports 1998;5(2):497-501.
1998: Rajani Ravi; E Weber; M McMahon; JR Williams; Stephen B Baylin; Asoke K Mal; Marian L Harter; Larry E Dillehay; P P Claudio; Antonio Giordano; Barry D Nelkin; M Mabry
Activated Raf-1 causes growth arrest in human small cell lung cancer cells.
The Journal of clinical investigation 1998;101(1):153-9.
1997: A Thiagalingam; Christoph Lengauer; Stephen B Baylin; Barry D Nelkin
RREB1, a ras responsive element binding protein, maps to human chromosome 6p25.
Genomics 1997;45(3):630-2.
1997: Herbert Chen; M A Biel; Michael W Borges; A Thiagalingam; Barry D Nelkin; Stephen B Baylin; Douglas W Ball
Tissue-specific expression of human achaete-scute homologue-1 in neuroendocrine tumors: transcriptional regulation by dual inhibitory regions.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1997;8(6):677-86.
1997: Herbert Chen; A Thiagalingam; H Chopra; Michael W Borges; J N Feder; Barry D Nelkin; Stephen B Baylin; Douglas W Ball
Conservation of the Drosophila lateral inhibition pathway in human lung cancer: a hairy-related protein (HES-1) directly represses achaete-scute homolog-1 expression.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(10):5355-60.
1997: M Borges; R Ilona Linnoila; H J van de Velde; Herbert Chen; Barry D Nelkin; M Mabry; Stephen B Baylin; Douglas W Ball
An achaete-scute homologue essential for neuroendocrine differentiation in the lung.
Nature 1997;386(6627):852-5.
1996: A Thiagalingam; A De Bustros; M Borges; R Jasti; D Compton; L Diamond; M Mabry; Douglas W Ball; Stephen B Baylin; Barry D Nelkin
RREB-1, a novel zinc finger protein, is involved in the differentiation response to Ras in human medullary thyroid carcinomas.
Molecular and cellular biology 1996;16(10):5335-45.
1996: James G Herman; Jeremy R Graff; S Myöhänen; Barry D Nelkin; Stephen B Baylin
Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(18):9821-6.
1996: Herbert Chen; Eleanor B Carson-Walter; Stephen B Baylin; Barry D Nelkin; Douglas W Ball
Differentiation of medullary thyroid cancer by C-Raf-1 silences expression of the neural transcription factor human achaete-scute homolog-1.
Surgery 1996;120(2):168-72; discussion 173.
1996: J Wu; James G Herman; G Wilson; R Y Lee; Ray-Whay Chiu Yen; M Mabry; A de Bustros; Barry D Nelkin; Stephen B Baylin
Expression of prokaryotic HhaI DNA methyltransferase is transforming and lethal to NIH 3T3 cells.
Cancer research 1996;56(3):616-22.
1995: M M Wales; M A Biel; Wafik S El-Deiry; Barry D Nelkin; Jean-Pierre J Issa; W K Cavenee; S J Kuerbitz; Stephen B Baylin
p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3.
Nature medicine 1995;1(6):570-7.
1995: E B Carson; M McMahon; Stephen B Baylin; Barry D Nelkin
Ret gene silencing is associated with Raf-1-induced medullary thyroid carcinoma cell differentiation.
Cancer research 1995;55(10):2048-52.
1994: L M McGregor; Stephen B Baylin; Constance A Griffin; Anita L Hawkins; Barry D Nelkin
Molecular cloning of the cDNA for human TrkC (NTRK3), chromosomal assignment, and evidence for a splice variant.
Genomics 1994;22(2):267-72.
1994: Barry D Nelkin; Douglas W Ball; Stephen B Baylin
Molecular abnormalities in tumors associated with multiple endocrine neoplasia type 2.
Endocrinology and metabolism clinics of North America 1994;23(1):187-213.
1994: Gregory P Kalemkerian; R K Jasti; P Celano; Barry D Nelkin; M Mabry
All-trans-retinoic acid alters myc gene expression and inhibits in vitro progression in small cell lung cancer.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994;5(1):55-60.
1993: J Wu; Jean-Pierre J Issa; James G Herman; D E Bassett; Barry D Nelkin; Stephen B Baylin
Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(19):8891-5.
1993: Jean-Pierre J Issa; Paula M Vertino; J Wu; Sunil Sazawal; P Celano; Barry D Nelkin; S R Hamilton; Stephen B Baylin
Increased cytosine DNA-methyltransferase activity during colon cancer progression.
Journal of the National Cancer Institute 1993;85(15):1235-40.
1993: Barry D Nelkin; Stephen B Baylin
Ret oncogene responsible for MEN2A.
Current biology : CB 1993;3(7):477-80.
1993: M Makos; Barry D Nelkin; Robert E Reiter; JR Gnarra; J Brooks; William B Isaacs; M Linehan; Stephen B Baylin
Regional DNA hypermethylation at D17S5 precedes 17p structural changes in the progression of renal tumors.
Cancer research 1993;53(12):2719-22.
1993: Douglas W Ball; Christopher G Azzoli; Stephen B Baylin; D Chi; S Dou; H Donis-Keller; A Cumaraswamy; M Borges; Barry D Nelkin
Identification of a human achaete-scute homolog highly expressed in neuroendocrine tumors.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(12):5648-52.
1993: M Makos; Barry D Nelkin; V R Chazin; W K Cavenee; G M Brodeur; Stephen B Baylin
DNA hypermethylation is associated with 17p allelic loss in neural tumors.
Cancer research 1993;53(12):2715-8.
1993: A Cumaraswamy; M Borges; H Tamir; Barry D Nelkin
Cloning of a cDNA encoding sheep calcitonin from a thyroid C-cell library.
Gene 1993;126(2):269-73.
1993: Stephen B Baylin; A C de Bustros; Douglas W Ball; Barry D Nelkin
Pathobiology of the C-cells.
Monographs in pathology 1993;(35):63-71.
1992: A de Bustros; Douglas W Ball; R Peters; D Compton; Barry D Nelkin
Regulation of human calcitonin gene transcription by cyclic AMP.
Biochemical and biophysical research communications 1992;189(2):1157-64.
1992: P Celano; C M Berchtold; D L Kizer; A Weeraratna; Barry D Nelkin; Stephen B Baylin; Robert A Casero
Characterization of an endogenous RNA transcript with homology to the antisense strand of the human c-myc gene.
The Journal of biological chemistry 1992;267(21):15092-6.
1992: Ray-Whay Chiu Yen; Paula M Vertino; Barry D Nelkin; J J Yu; Wafik S El-Deiry; A Cumaraswamy; G G Lennon; Barbara J Trask; P Celano; Stephen B Baylin
Isolation and characterization of the cDNA encoding human DNA methyltransferase.
Nucleic acids research 1992;20(9):2287-91.
1992: M Makos; Barry D Nelkin; M I Lerman; F Latif; B Zbar; Stephen B Baylin
Distinct hypermethylation patterns occur at altered chromosome loci in human lung and colon cancer.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(5):1929-33.
1992: Jeffrey F Moley; M B Brother; C T Fong; P S White; Stephen B Baylin; Barry D Nelkin; Samuel A Wells; Garrett M Brodeur
Consistent association of 1p loss of heterozygosity with pheochromocytomas from patients with multiple endocrine neoplasia type 2 syndromes.
Cancer research 1992;52(4):770-4.
1992: Douglas W Ball; D Compton; Barry D Nelkin; Stephen B Baylin; A de Bustros
Human calcitonin gene regulation by helix-loop-helix recognition sequences.
Nucleic acids research 1992;20(1):117-23.
1991: L F Barr; M Mabry; Barry D Nelkin; G Tyler; W S May; Stephen B Baylin
c-myc gene-induced alterations in protein kinase C expression: a possible mechanism facilitating myc-ras gene complementation.
Cancer research 1991;51(20):5514-9.
1991: Stephen B Baylin; M Makos; J J Wu; Ray-Whay Chiu Yen; A de Bustros; Paula M Vertino; Barry D Nelkin
Abnormal patterns of DNA methylation in human neoplasia: potential consequences for tumor progression.
Cancer cells (Cold Spring Harbor, N.Y. : 1989) 1991;3(10):383-90.
1991: Barry D Nelkin; D Przepiorka; PJ Burke; E D Thomas; Stephen B Baylin
Abnormal methylation of the calcitonin gene marks progression of chronic myelogenous leukemia.
Blood 1991;77(11):2431-4.
1991: Wafik S El-Deiry; Barry D Nelkin; P Celano; Ray-Whay Chiu Yen; J P Falco; S R Hamilton; Stephen B Baylin
High expression of the DNA methyltransferase gene characterizes human neoplastic cells and progression stages of colon cancer.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(8):3470-4.
1991: M Mabry; Barry D Nelkin; J P Falco; L F Barr; Stephen B Baylin
Transitions between lung cancer phenotypes--implications for tumor progression.
Cancer cells (Cold Spring Harbor, N.Y. : 1989) 1991;3(2):53-8.
1990: Barry D Nelkin; M Borges; M Mabry; Stephen B Baylin
Transcription factor levels in medullary thyroid carcinoma cells differentiated by Harvey ras oncogene: c-jun is increased.
Biochemical and biophysical research communications 1990;170(1):140-6.
1990: Barry D Nelkin
Labeling of double-stranded oligonucleotides to high specific activity.
BioTechniques 1990;8(6):616, 618.
1990: J P Falco; Stephen B Baylin; R Lupu; M Borges; Barry D Nelkin; R K Jasti; Nancy E Davidson; M Mabry
v-rasH induces non-small cell phenotype, with associated growth factors and receptors, in a small cell lung cancer cell line.
The Journal of clinical investigation 1990;85(6):1740-5.
1990: H Brauch; Farida Latif; Stephen B Baylin; Barry D Nelkin; S Hosoe; L Daniel; Gladys Glenn; I Danko; W E Bradley; M L Orcutt
MspI and DraI polymorphisms at the ERBA beta locus on chromosome 3p.
Nucleic acids research 1990;18(9):2833.
1990: A de Bustros; R Y Lee; D Compton; T Y Tsong; Stephen B Baylin; Barry D Nelkin
Differential utilization of calcitonin gene regulatory DNA sequences in cultured lines of medullary thyroid carcinoma and small-cell lung carcinoma.
Molecular and cellular biology 1990;10(4):1773-8.
1989: Barry D Nelkin; K Y Chen; A de Bustros; Bernard A Roos; Stephen B Baylin
Changes in calcitonin gene RNA processing during growth of a human medullary thyroid carcinoma cell line.
Cancer research 1989;49(24 Pt 1):6949-52.
1989: Barry D Nelkin; Y Nakamura; R W White; A C de Bustros; James G Herman; S A Wells; Stephen B Baylin
Low incidence of loss of chromosome 10 in sporadic and hereditary human medullary thyroid carcinoma.
Cancer research 1989;49(15):4114-9.
1989: M Mabry; T Nakagawa; Stephen B Baylin; O Pettengill; G Sorenson; Barry D Nelkin
Insertion of the v-Ha-ras oncogene induces differentiation of calcitonin-producing human small cell lung cancer.
The Journal of clinical investigation 1989;84(1):194-9.
1989: Barry D Nelkin; A C de Bustros; M Mabry; Stephen B Baylin
The molecular biology of medullary thyroid carcinoma. A model for cancer development and progression.
JAMA : the journal of the American Medical Association 1989;261(21):3130-5.
1989: FREDERICK HAUSHEER; S N Rao; Michael P Gamcsik; P A Kollman; O Michael Colvin; J D Saxe; Barry D Nelkin; I J McLennan; G Barnett; Stephen B Baylin
Computational analysis of structural and energetic consequences of DNA methylation.
Carcinogenesis 1989;10(6):1131-7.
1988: M Mabry; T Nakagawa; Barry D Nelkin; E McDowell; M Gesell; J C Eggleston; Robert A Casero; Stephen B Baylin
v-Ha-ras oncogene insertion: a model for tumor progression of human small cell lung cancer.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(17):6523-7.
1988: A de Bustros; Barry D Nelkin; Ann L. Silverman; G Ehrlich; Bernard J Poiesz; Stephen B Baylin
The short arm of chromosome 11 is a "hot spot" for hypermethylation in human neoplasia.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(15):5693-7.
1988: P Celano; Stephen B Baylin; Francis M Giardiello; Barry D Nelkin; Robert A Casero
Effect of polyamine depletion on c-myc expression in human colon carcinoma cells.
The Journal of biological chemistry 1988;263(12):5491-4.
1988: T Nakagawa; Barry D Nelkin; Stephen B Baylin; A de Bustros
Transcriptional and posttranscriptional modulation of calcitonin gene expression by sodium n-butyrate in cultured human medullary thyroid carcinoma.
Cancer research 1988;48(8):2096-100.
1987: Stephen B Baylin; Eric R Fearon; Bert Vogelstein; A de Bustros; Saul J Sharkis; P J Burke; S P Staal; Barry D Nelkin
Hypermethylation of the 5' region of the calcitonin gene is a property of human lymphoid and acute myeloid malignancies.
Blood 1987;70(2):412-7.
1987: T Nakagawa; M Mabry; A de Bustros; J N Ihle; Barry D Nelkin; Stephen B Baylin
Introduction of v-Ha-ras oncogene induces differentiation of cultured human medullary thyroid carcinoma cells.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(16):5923-7.
1987: Lee Helman; Carol Jeanne Thiele; W M Linehan; Barry D Nelkin; Stephen B Baylin; Mark Israel
Molecular markers of neuroendocrine development and evidence of environmental regulation.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(8):2336-9.
1987: K Tanaka; Stephen B Baylin; Barry D Nelkin; J R Testa
Cytogenetic studies of a human medullary thyroid carcinoma cell line.
Cancer genetics and cytogenetics 1987;25(1):27-35.
1986: A deBustros; Stephen B Baylin; Michael A. Levine; Barry D Nelkin
Cyclic AMP and phorbol esters separately induce growth inhibition, calcitonin secretion, and calcitonin gene transcription in cultured human medullary thyroid carcinoma.
The Journal of biological chemistry 1986;261(17):8036-41.
1986: Stephen B Baylin; Jo W M Höppener; A de Bustros; Paul H Steenbergh; C J Lips; Barry D Nelkin
DNA methylation patterns of the calcitonin gene in human lung cancers and lymphomas.
Cancer research 1986;46(6):2917-22.
1986: Robert A Casero; Stephen B Baylin; Barry D Nelkin; GD Luk
Human lung tumor sensitivity to difluoromethylornithine as related to ornithine decarboxylase messenger RNA levels.
Biochemical and biophysical research communications 1986;134(2):572-9.
1985: S D Kittur; J W Hoppener; S E Antonarakis; J D Daniels; Deborah A Meyers; N E Maestri; M Jansen; R G Korneluk; Barry D Nelkin; Haig Kazazian
Linkage map of the short arm of human chromosome 11: location of the genes for catalase, calcitonin, and insulin-like growth factor II.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(15):5064-7.
1985: Donald Small; Barry D Nelkin; Bert Vogelstein
The association of transcribed genes with the nuclear matrix of Drosophila cells during heat shock.
Nucleic acids research 1985;13(7):2413-31.
1985: A de Bustros; Stephen B Baylin; C L Berger; Bernard A Roos; S S Leong; Barry D Nelkin
Phorbol esters increase calcitonin gene transcription and decrease c-myc mRNA levels in cultured human medullary thyroid carcinoma.
The Journal of biological chemistry 1985;260(1):98-104.
1985: Jo W M Höppener; Paul H Steenbergh; J Zandberg; A H Geurts van Kessel; Stephen B Baylin; Barry D Nelkin; H S Jansz; Cornelis J M Lips
The second human calcitonin/CGRP gene is located on chromosome 11.
Human genetics 1985;70(3):259-63.
1984: Barry D Nelkin; K I Rosenfeld; A de Bustros; S S Leong; Bernard A Roos; Stephen B Baylin
Structure and expression of a gene encoding human calcitonin and calcitonin gene related peptide.
Biochemical and biophysical research communications 1984;123(2):648-55.
1984: D Przepiorka; Stephen B Baylin; O W McBride; J R Testa; A de Bustros; Barry D Nelkin
The human calcitonin gene is located on the short arm of chromosome 11.
Biochemical and biophysical research communications 1984;120(2):493-9.
1983: Andrew P Feinberg; Bert Vogelstein; M J Droller; Stephen B Baylin; Barry D Nelkin
Mutation affecting the 12th amino acid of the c-Ha-ras oncogene product occurs infrequently in human cancer.
Science (New York, N.Y.) 1983;220(4602):1175-7.
1982: Donald Small; Barry D Nelkin; Bert Vogelstein
Nonrandom distribution of repeated DNA sequences with respect to supercoiled loops and the nuclear matrix.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(19):5911-5.
1982: S I Robinson; Barry D Nelkin; Bert Vogelstein
The ovalbumin gene is associated with the nuclear matrix of chicken oviduct cells.
Cell 1982;28(1):99-106.
1981: S I Robinson; Barry D Nelkin; S Kaufmann; Bert Vogelstein
Increased phosphorylation rate of intermediate filaments during mitotic arrest.
Experimental cell research 1981;133(2):445-8.
1980: Barry D Nelkin; Drew M Pardoll; Bert Vogelstein
Localization of SV40 genes within supercoiled loop domains.
Nucleic acids research 1980;8(23):5623-33.
1980: Barry D Nelkin; D Strayer; Bert Vogelstein
Divergence of primate ribosomal RNA genes as assayed by restriction enzyme analysis.
Gene 1980;11(1-2):89-96.
1980: Barry D Nelkin; C Nichols; Bert Vogelstein
Protein factor(s) from mitotic CHO cells induce meiotic maturation in Xenopus laevis oocytes.
FEBS letters 1980;109(2):233-8.