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Jay Nelson

Research Profile

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Chemicals & Drugs

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Cytomegalovirus Infections

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TOP 3
Kasinath Viswanathan; Daniel Malouli; Mandana Mansouri; Jay A Nelson; M Shane Smith; Klaus J Frueh
BST2/Tetherin enhances entry of human cytomegalovirus.
David A Stein; Michael D Buck; Matthew A Fischer; Alec J Hirsch; Alissa M Lancaster; Jay A Nelson; Christopher S Oehmen; Stuart T Perry; Elizabeth Poore; Sujan Shresta; Mark K Slifka; Jessica L Smith; Klaus J Frueh
Inhibition of dengue virus infections in cell cultures and in AG129 mice by a small interfering RNA targeting a highly conserved sequence.
Scott G Hansen; Julia C Ford; Matthew S Lewis; Abigail B Ventura; Colette M Hughes; Lia Coyne-Johnson; Nathan Whizin; Kelli Oswald; Rebecca Shoemaker; Tonya Swanson; Alfred W Legasse; Maria J Chiuchiolo; Christopher L Parks; Michael K Axthelm; Jay A Nelson; Michael A Jarvis; Michael Piatak; Jeffrey D Lifson; Louis J Picker
Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine.

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All Publications

2011: Kasinath Viswanathan; Daniel Malouli; Mandana Mansouri; Jay A Nelson; M Shane Smith; Klaus J Frueh
BST2/Tetherin enhances entry of human cytomegalovirus.
PLoS pathogens 2011;7(11):e1002332.
2011: David A Stein; Michael D Buck; Matthew A Fischer; Alec J Hirsch; Alissa M Lancaster; Jay A Nelson; Christopher S Oehmen; Stuart T Perry; Elizabeth Poore; Sujan Shresta; Mark K Slifka; Jessica L Smith; Klaus J Frueh
Inhibition of dengue virus infections in cell cultures and in AG129 mice by a small interfering RNA targeting a highly conserved sequence.
Journal of virology 2011;85(19):10154-66.
2011: Scott G Hansen; Julia C Ford; Matthew S Lewis; Abigail B Ventura; Colette M Hughes; Lia Coyne-Johnson; Nathan Whizin; Kelli Oswald; Rebecca Shoemaker; Tonya Swanson; Alfred W Legasse; Maria J Chiuchiolo; Christopher L Parks; Michael K Axthelm; Jay A Nelson; Michael A Jarvis; Michael Piatak; Jeffrey D Lifson; Louis J Picker
Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine.
Nature 2011;473(7348):523-7.
2010: M Shane Smith; Devorah C Goldman; Alexis S Bailey; Dana L Pfaffle; Craig N Kreklywich; Doran B Spencer; Florence A Othieno; Daniel N Streblow; J Victor Garcia; William H Fleming; Jay A Nelson
Granulocyte-colony stimulating factor reactivates human cytomegalovirus in a latently infected humanized mouse model.
Cell host & microbe 2010;8(3):284-91.
2010: Scott G Hansen; Colin J Powers; Rebecca Richards; Abigail B Ventura; Julia C Ford; Don Siess; Michael K Axthelm; Jay A Nelson; Michael A Jarvis; Louis J Picker; Klaus J Frueh
Evasion of CD8+ T cells is critical for superinfection by cytomegalovirus.
Science (New York, N.Y.) 2010;328(5974):102-6.
2010: Paul T Wille; Amber J Knoche; Jay A Nelson; Michael A Jarvis; David C Johnson
A human cytomegalovirus gO-null mutant fails to incorporate gH/gL into the virion envelope and is unable to enter fibroblasts and epithelial and endothelial cells.
Journal of virology 2010;84(5):2585-96.
2010: Finn E Grey; Rebecca Tirabassi; Heather Meyers; Guanming Wu; Shannon McWeeney; Lauren Hook; Jay A Nelson
A viral microRNA down-regulates multiple cell cycle genes through mRNA 5'UTRs.
PLoS pathogens 2010;6(6):e1000967.
2009: Jennifer Vomaske; Jay A Nelson; Daniel N Streblow
Human Cytomegalovirus US28: a functionally selective chemokine binding receptor.
Infectious disorders drug targets 2009;9(5):548-56.
2009: Guruprasad R Medigeshi; Alec J Hirsch; James Brien; Jennifer L Uhrlaub; Peter W Mason; Clayton Wiley; Janko Nikolich-Zugich; Jay A Nelson
West nile virus capsid degradation of claudin proteins disrupts epithelial barrier function.
Journal of virology 2009;83(12):6125-34.
2009: Carmen C Baca Jones; Craig N Kreklywich; Ilhem Messaoudi; Jennifer Vomaske; Erin McCartney; Susan L Orloff; Jay A Nelson; Daniel N Streblow
Rat cytomegalovirus infection depletes MHC II in bone marrow derived dendritic cells.
Virology 2009;388(1):78-90.
2009: Alan G Goodman; Jamie L Fornek; Guruprasad R Medigeshi; Lucy A Perrone; Xinxia Peng; Matthew D Dyer; Sean C Proll; Sue E Knoblaugh; Victoria S Carter; Marcus J Korth; Jay A Nelson; Terrence M Tumpey; Michael G Katze
P58(IPK): a novel "CIHD" member of the host innate defense response against pathogenic virus infection.
PLoS pathogens 2009;5(5):e1000438.
2009: Scott G Hansen; Cassandra Vieville; Nathan Whizin; Lia Coyne-Johnson; Don C Siess; Derek D Drummond; Alfred W Legasse; Michael K Axthelm; Kelli Oswald; Charles M Trubey; Michael Piatak; Jeffrey D Lifson; Jay A Nelson; Michael A Jarvis; Louis J Picker
Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge.
Nature medicine 2009;15(3):293-9.
2009: Jennifer Vomaske; Ryan M Melnychuk; Patsy P Smith; Joshua Powell; Laurel Hall; Victor DeFilippis; Klaus J Frueh; Martine Smit; David D Schlaepfer; Jay A Nelson; Daniel N Streblow
Differential ligand binding to a human cytomegalovirus chemokine receptor determines cell type-specific motility.
PLoS pathogens 2009;5(2):e1000304.
2008: Jerome Dumortier; Daniel N Streblow; Ashlee V Moses; Jon M Jacobs; Craig N Kreklywich; David Camp; Richard D Smith; Susan L Orloff; Jay A Nelson
Human cytomegalovirus secretome contains factors that induce angiogenesis and wound healing.
Journal of virology 2008;82(13):6524-35.
2008: Guruprasad R Medigeshi; Alec J Hirsch; Daniel N Streblow; Janko Nikolich-Zugich; Jay A Nelson
West Nile virus entry requires cholesterol-rich membrane microdomains and is independent of alphavbeta3 integrin.
Journal of virology 2008;82(11):5212-9.
2008: Finn E Grey; Lauren Hook; Jay A Nelson
The functions of herpesvirus-encoded microRNAs.
Medical microbiology and immunology 2008;197(2):261-7.
2008: Finn E Grey; Jay A Nelson
Identification and function of human cytomegalovirus microRNAs.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2008;41(3):186-91.
2008: Daniel N Streblow; Craig N Kreklywich; T Andoh; Ashlee V Moses; J Dumortier; Patsy P Smith; Victor DeFilippis; Klaus J Frueh; Jay A Nelson; Susan L Orloff
The role of angiogenic and wound repair factors during CMV-accelerated transplant vascular sclerosis in rat cardiac transplants.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2008;8(2):277-87.
2008: Daniel N Streblow; J Dumortier; Ashlee V Moses; Susan L Orloff; Jay A Nelson
Mechanisms of cytomegalovirus-accelerated vascular disease: induction of paracrine factors that promote angiogenesis and wound healing.
Current topics in microbiology and immunology 2008;325():397-415.
2008: Brent J Ryckman; Barb L Rainish; Marie C Chase; Jamie A Borton; Jay A Nelson; Michael A Jarvis; David C Johnson
Characterization of the human cytomegalovirus gH/gL/UL128-131 complex that mediates entry into epithelial and endothelial cells.
Journal of virology 2008;82(1):60-70.
2007: Jay A Nelson
Small RNAs and large DNA viruses.
The New England journal of medicine 2007;357(25):2630-2.
2007: Finn E Grey; Heather Meyers; Elizabeth A White; Deborah H Spector; Jay A Nelson
A human cytomegalovirus-encoded microRNA regulates expression of multiple viral genes involved in replication.
PLoS pathogens 2007;3(11):e163.
2007: Daniel N Streblow; Susan L Orloff; Jay A Nelson
Acceleration of allograft failure by cytomegalovirus.
Current opinion in immunology 2007;19(5):577-82.
2007: Guruprasad R Medigeshi; Alissa M Lancaster; Alec J Hirsch; Thomas Briese; W Ian Lipkin; Victor DeFilippis; Klaus J Frueh; Peter W Mason; Janko Nikolich-Zugich; Jay A Nelson
West Nile virus infection activates the unfolded protein response, leading to CHOP induction and apoptosis.
Journal of virology 2007;81(20):10849-60.
2007: Daniel N Streblow; Koen W R van Cleef; Craig N Kreklywich; Christine Meyer; Patricia Smith; Victor DeFilippis; Finn E Grey; Klaus J Frueh; Robert Searles; Cathrien Bruggeman; Cornelis Vink; Jay A Nelson; Susan L Orloff
Rat cytomegalovirus gene expression in cardiac allograft recipients is tissue specific and does not parallel the profiles detected in vitro.
Journal of virology 2007;81(8):3816-26.
2007: Michael A Jarvis; Jay A Nelson
Human cytomegalovirus tropism for endothelial cells: not all endothelial cells are created equal.
Journal of virology 2007;81(5):2095-101.
2006: Michael A Jarvis; Jamie A Borton; Amy M Keech; John Wong; William J Britt; Bruce E Magun; Jay A Nelson
Human cytomegalovirus attenuates interleukin-1beta and tumor necrosis factor alpha proinflammatory signaling by inhibition of NF-kappaB activation.
Journal of virology 2006;80(11):5588-98.
2006: Victor DeFilippis; Bridget Robinson; Thomas M Keck; Scott G Hansen; Jay A Nelson; Klaus J Frueh
Interferon regulatory factor 3 is necessary for induction of antiviral genes during human cytomegalovirus infection.
Journal of virology 2006;80(2):1032-7.
2006: Brent J Ryckman; Michael A Jarvis; Derek D Drummond; Jay A Nelson; David C Johnson
Human cytomegalovirus entry into epithelial and endothelial cells depends on genes UL128 to UL150 and occurs by endocytosis and low-pH fusion.
Journal of virology 2006;80(2):710-22.
2005: Sandra Delmas; Laurence Martin; Michel Baron; Jay A Nelson; Daniel N Streblow; Jean-Luc Davignon
Optimization of CD4+ T lymphocyte response to human cytomegalovirus nuclear IE1 protein through modifications of both size and cellular localization.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(10):6812-9.
2005: Nagendra R Hegde; Claire Dunn; David M Lewinsohn; Michael A Jarvis; Jay A Nelson; David C Johnson
Endogenous human cytomegalovirus gB is presented efficiently by MHC class II molecules to CD4+ CTL.
The Journal of experimental medicine 2005;202(8):1109-19.
2005: Andrew W Sylwester; Bridget L Mitchell; John B Edgar; Cara Taormina; Christian Pelte; Franziska Ruchti; Paul R Sleath; Kenneth H Grabstein; Nancy A Hosken; Florian Kern; Jay A Nelson; Louis J Picker
Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects.
The Journal of experimental medicine 2005;202(5):673-85.
2005: Finn E Grey; Andy Antoniewicz; Edwards Allen; Julie Saugstad; Andy McShea; James C Carrington; Jay A Nelson
Identification and characterization of human cytomegalovirus-encoded microRNAs.
Journal of virology 2005;79(18):12095-9.
2005: Alec J Hirsch; Guruprasad R Medigeshi; Heather L Meyers; Victor DeFilippis; Klaus J Frueh; Thomas Briese; W Ian Lipkin; Jay A Nelson
The Src family kinase c-Yes is required for maturation of West Nile virus particles.
Journal of virology 2005;79(18):11943-51.
2005: Ryan M Melnychuk; Patsy Smith; Craig N Kreklywich; Franziska Ruchti; Jennifer Vomaske; Laurel Hall; Lambert Loh; Jay A Nelson; Susan L Orloff; Daniel N Streblow
Mouse cytomegalovirus M33 is necessary and sufficient in virus-induced vascular smooth muscle cell migration.
Journal of virology 2005;79(16):10788-95.
2005: Daniel N Streblow; Craig N Kreklywich; Patricia Smith; Jordana L Soule; Christine Meyer; Michael Yin; Patrick S Beisser; Cornelis Vink; Jay A Nelson; Susan L Orloff
Rat cytomegalovirus-accelerated transplant vascular sclerosis is reduced with mutation of the chemokine-receptor R33.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2005;5(3):436-42.
2004: Cary A Rue; Michael A Jarvis; Amber J Knoche; Heather L Meyers; Victor DeFilippis; Scott G Hansen; Markus Wagner; Klaus J Frueh; David G Anders; Scott W Wong; Peter A Barry; Jay A Nelson
A cyclooxygenase-2 homologue encoded by rhesus cytomegalovirus is a determinant for endothelial cell tropism.
Journal of virology 2004;78(22):12529-36.
2004: Susan M Varnum; Daniel N Streblow; Matthew Monroe; Patricia Smith; Kenneth J Auberry; Ljiljana Pasa-Tolic; Dai Wang; David G Camp; Karin Rodland; Steven Wiley; William J Britt; Thomas Shenk; Richard D Smith; Jay A Nelson
Identification of proteins in human cytomegalovirus (HCMV) particles: the HCMV proteome.
Journal of virology 2004;78(20):10960-6.
2004: Ryan M Melnychuk; Daniel N Streblow; Patsy P Smith; Alec J Hirsch; Dora Pancheva; Jay A Nelson
Human cytomegalovirus-encoded G protein-coupled receptor US28 mediates smooth muscle cell migration through Galpha12.
Journal of virology 2004;78(15):8382-91.
2004: Winnie W Henderson; Rebecca Ruhl; Paul F Lewis; Matthew Bentley; Jay A Nelson; Ashlee V Moses
Human immunodeficiency virus (HIV) type 1 Vpu induces the expression of CD40 in endothelial cells and regulates HIV-induced adhesion of B-lymphoma cells.
Journal of virology 2004;78(9):4408-20.
2004: Dusko Ilić; Branka Kovacic; Kohei Johkura; David D Schlaepfer; Nenad Tomasević; Qin Han; Jae-Beom Kim; Kyle Howerton; Clark Baumbusch; Naoko Ogiwara; Daniel N Streblow; Jay A Nelson; Paul Dazin; Yuji Shino; Katsunori Sasaki; Caroline Damsky
FAK promotes organization of fibronectin matrix and fibrillar adhesions.
Journal of cell science 2004;117(Pt 2):177-87.
2004: William J Britt; Michael A Jarvis; Jun-Young Seo; Derek Drummond; Jay A Nelson
Rapid genetic engineering of human cytomegalovirus by using a lambda phage linear recombination system: demonstration that pp28 (UL99) is essential for production of infectious virus.
Journal of virology 2004;78(1):539-43.
2004: Michael A Jarvis; Thomas R Jones; Derek D Drummond; Patsy P Smith; William J Britt; Jay A Nelson; Carl J Baldick
Phosphorylation of human cytomegalovirus glycoprotein B (gB) at the acidic cluster casein kinase 2 site (Ser900) is required for localization of gB to the trans-Golgi network and efficient virus replication.
Journal of virology 2004;78(1):285-93.
2003: Daniel N Streblow; Jennifer Vomaske; Patsy Smith; Ryan M Melnychuk; Laurel Hall; Dora Pancheva; Martine Smit; Paola Casarosa; David D Schlaepfer; Jay A Nelson
Human cytomegalovirus chemokine receptor US28-induced smooth muscle cell migration is mediated by focal adhesion kinase and Src.
The Journal of biological chemistry 2003;278(50):50456-65.
2003: Eain Murphy; Dong Yu; Jane Grimwood; Jeremy Schmutz; Mark Dickson; Michael A Jarvis; Gabriele Hahn; Jay A Nelson; Richard Myers; Thomas Shenk
Coding potential of laboratory and clinical strains of human cytomegalovirus.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(25):14976-81.
2003: Erika Hammarlund; Matthew W Lewis; Scott G Hansen; Lisa I Strelow; Jay A Nelson; Gary J Sexton; Jon M Hanifin; Mark K Slifka
Duration of antiviral immunity after smallpox vaccination.
Nature medicine 2003;9(9):1131-7.
2003: Daniel N Streblow; Jay A Nelson
Models of HCMV latency and reactivation.
Trends in microbiology 2003;11(7):293-5.
2003: Datsun A Hsia; Satyajit Mitra; Christof R Hauck; Daniel N Streblow; Jay A Nelson; Dusko Ilic; Shuang Huang; Erguang Li; Glen R Nemerow; Jay Leng; Kathryn S R Spencer; David A Cheresh; David D Schlaepfer
Differential regulation of cell motility and invasion by FAK.
The Journal of cell biology 2003;160(5):753-67.
2003: Daniel N Streblow; Craig N Kreklywich; Qiang Yin; VT De La Melena; Christopher L Corless; Patricia A Smith; Christina Brakebill; Judith W Cook; Cornelis Vink; Cathrien A Bruggeman; Jay A Nelson; Susan L Orloff
Cytomegalovirus-mediated upregulation of chemokine expression correlates with the acceleration of chronic rejection in rat heart transplants.
Journal of virology 2003;77(3):2182-94.
2002: Ashlee V Moses; Michael A Jarvis; Camilo Raggo; Yolanda C Bell; Rebecca Ruhl; B G Mattias Luukkonen; Diana J Griffith; Cecily L Wait; Brian J Druker; Michael C Heinrich; Jay A Nelson; Klaus J Frueh
A functional genomics approach to Kaposi's sarcoma.
Annals of the New York Academy of Sciences 2002;975():180-91.
2002: Lisa Strelow; Damir Janigro; Jay A Nelson
Persistent SIV infection of a blood-brain barrier model.
Journal of neurovirology 2002;8(4):270-80.
2002: Michael A Jarvis; Jay A Nelson
Human cytomegalovirus persistence and latency in endothelial cells and macrophages.
Current opinion in microbiology 2002;5(4):403-7.
2002: Ashlee V Moses; Michael A Jarvis; Camilo Raggo; Yolanda C Bell; Rebecca Ruhl; B G Mattias Luukkonen; Diana J Griffith; Cecily L Wait; Brian J Druker; Michael C Heinrich; Jay A Nelson; Klaus J Frueh
Kaposi's sarcoma-associated herpesvirus-induced upregulation of the c-kit proto-oncogene, as identified by gene expression profiling, is essential for the transformation of endothelial cells.
Journal of virology 2002;76(16):8383-99.
2002: Emmanuelle Le Roy; Michel Baron; Wolfgang Faigle; Danièle Clément; David M Lewinsohn; Daniel N Streblow; Jay A Nelson; Sebastian Amigorena; Jean-Luc Davignon
Infection of APC by human cytomegalovirus controlled through recognition of endogenous nuclear immediate early protein 1 by specific CD4(+) T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(3):1293-301.
2002: Michael A Jarvis; Jay A Nelson
Mechanisms of human cytomegalovirus persistence and latency.
Frontiers in bioscience : a journal and virtual library 2002;7():d1575-82.
2002: Michael A Jarvis; Kenneth N Fish; Cecilia Söderberg-Naucler; Daniel N Streblow; Heather L Meyers; Gary Thomas; Jay A Nelson
Retrieval of human cytomegalovirus glycoprotein B from cell surface is not required for virus envelopment in astrocytoma cells.
Journal of virology 2002;76(10):5147-55.
2002: Susan L Orloff; Daniel N Streblow; Cecilia Soderberg-Naucler; Qiang Yin; Craig N Kreklywich; Christopher L Corless; Patricia A Smith; Christopher B Loomis; Lisa K Mills; Judith W Cook; Cathrien A Bruggeman; Jay A Nelson; Cynthia R Wagner
Elimination of donor-specific alloreactivity prevents cytomegalovirus-accelerated chronic rejection in rat small bowel and heart transplants.
Transplantation 2002;73(5):679-88.
2001: Daniel N Streblow; Susan L Orloff; Jay A Nelson
Do pathogens accelerate atherosclerosis?
The Journal of nutrition 2001;131(10):2798S-2804S.
2001: Daniel N Streblow; Susan L Orloff; Jay A Nelson
The HCMV chemokine receptor US28 is a potential target in vascular disease.
Current drug targets. Infectious disorders 2001;1(2):151-8.
2001: C Söderberg-Nauclér; Daniel N Streblow; Kenneth N Fish; J Allan-Yorke; Patsy P Smith; Jay A Nelson
Reactivation of latent human cytomegalovirus in CD14(+) monocytes is differentiation dependent.
Journal of virology 2001;75(16):7543-54.
2001: M R Wallace; Jay A Nelson; J Allen McCutchan; Tanya Wolfson; Igor Grant
Symptomatic HIV seroconverting illness is associated with more rapid neurological impairment.
Sexually transmitted infections 2001;77(3):199-201.
2001: VT De La Melena; Craig N Kreklywich; Daniel N Streblow; Qiang Yin; Judith W Cook; Cecilia Soderberg-Naucler; Cathrien A Bruggeman; Jay A Nelson; Susan L Orloff
Kinetics and development of CMV-accelerated transplant vascular sclerosis in rat cardiac allografts is linked to early increase in chemokine expression and presence of virus.
Transplantation proceedings 2001;33(1-2):1822-3.
2001: L I Strelow; Damir Janigro; Jay A Nelson
The blood-brain barrier and AIDS.
Advances in virus research 2001;56():355-88.
2000: Eain Murphy; Daniel N Streblow; Jay A Nelson; Mark F Stinski
The human cytomegalovirus IE86 protein can block cell cycle progression after inducing transition into the S phase of permissive cells.
Journal of virology 2000;74(15):7108-18.
2000: François Jean; Laurel Thomas; Sean S Molloy; G Liu; Michael A Jarvis; Jay A Nelson; Gary Thomas
A protein-based therapeutic for human cytomegalovirus infection.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(6):2864-9.
1999: LM Dallasta; LA Pisarov; James Esplen; J V Werley; Ashlee V Moses; Jay A Nelson; Cristian L Achim
Blood-brain barrier tight junction disruption in human immunodeficiency virus-1 encephalitis.
The American journal of pathology 1999;155(6):1915-27.
1999: Daniel N Streblow; Cecilia Soderberg-Naucler; Jeffrey Vieira; Patsy Smith; E Wakabayashi; F Ruchti; Kirsten Mattison; Y Altschuler; Jay A Nelson
The human cytomegalovirus chemokine receptor US28 mediates vascular smooth muscle cell migration.
Cell 1999;99(5):511-20.
1999: Roman A Tomazin; Jessica M Boname; Nagendra R Hegde; David M Lewinsohn; Y Altschuler; T R Jones; P Cresswell; Jay A Nelson; S R Riddell; David C Johnson
Cytomegalovirus US2 destroys two components of the MHC class II pathway, preventing recognition by CD4+ T cells.
Nature medicine 1999;5(9):1039-43.
1999: Ashlee V Moses; Kenneth N Fish; Rebecca Ruhl; Patsy P Smith; J G Strussenberg; L Zhu; bala chandran; Jay A Nelson
Long-term infection and transformation of dermal microvascular endothelial cells by human herpesvirus 8.
Journal of virology 1999;73(8):6892-902.
1999: Michael A Jarvis; C E Wang; Heather L Meyers; Patsy P Smith; Christopher L Corless; G J Henderson; Jeffrey Vieira; William J Britt; Jay A Nelson
Human cytomegalovirus infection of caco-2 cells occurs at the basolateral membrane and is differentiation state dependent.
Journal of virology 1999;73(6):4552-60.
1998: C Söderberg-Nauclér; Kenneth N Fish; Jay A Nelson
Growth of human cytomegalovirus in primary macrophages.
Methods (San Diego, Calif.) 1998;16(1):126-38.
1998: Kenneth N Fish; Cecilia Soderberg-Naucler; Jay A Nelson
Steady-state plasma membrane expression of human cytomegalovirus gB is determined by the phosphorylation state of Ser900.
Journal of virology 1998;72(8):6657-64.
1998: Kenneth N Fish; Cecilia Soderberg-Naucler; L K Mills; S Stenglein; Jay A Nelson
Human cytomegalovirus persistently infects aortic endothelial cells.
Journal of virology 1998;72(7):5661-8.
1998: L I Strelow; Debbie D Watry; Howard S Fox; Jay A Nelson
Efficient infection of brain microvascular endothelial cells by an in vivo-selected neuroinvasive SIVmac variant.
Journal of neurovirology 1998;4(3):269-80.
1998: CM Jackow; N Puffer; Maria Hordinsky; Jay A Nelson; J Tarrand; Madeleine Duvic
Alopecia areata and cytomegalovirus infection in twins: genes versus environment?
Journal of the American Academy of Dermatology 1998;38(3):418-25.
1998: Ashlee V Moses; Jay A Nelson; Grover C Bagby
The influence of human immunodeficiency virus-1 on hematopoiesis.
Blood 1998;91(5):1479-95.
1997: C Söderberg-Nauclér; Kenneth N Fish; Jay A Nelson
Interferon-gamma and tumor necrosis factor-alpha specifically induce formation of cytomegalovirus-permissive monocyte-derived macrophages that are refractory to the antiviral activity of these cytokines.
The Journal of clinical investigation 1997;100(12):3154-63.
1997: Charlene F Barroga; R Ellis; Jay A Nelson; R K Heaton; J Hampton Atkinson; J Allen McCutchan; I Grant; Stephen A Spector
HIV-1 neurocognitive disorders and chemokine receptors.
AIDS (London, England) 1997;11(13):1651-2.
1997: Ashlee V Moses; S E Williams; J G Strussenberg; M L Heneveld; Rebecca Ruhl; Antony C (Tony) Bakke; Grover C Bagby; Jay A Nelson
HIV-1 induction of CD40 on endothelial cells promotes the outgrowth of AIDS-associated B-cell lymphomas.
Nature medicine 1997;3(11):1242-9.
1997: Kathe A Stanness; Lesnick E Westrum; E Fornaciari; P Mascagni; Jay A Nelson; S G Stenglein; T Myers; Damir Janigro
Morphological and functional characterization of an in vitro blood-brain barrier model.
Brain research 1997;771(2):329-42.
1997: C Söderberg-Nauclér; Kenneth N Fish; Jay A Nelson
Reactivation of latent human cytomegalovirus by allogeneic stimulation of blood cells from healthy donors.
Cell 1997;91(1):119-26.
1997: M R Wallace; R K Heaton; J Allen McCutchan; J L Malone; R Velin; Jay A Nelson; L K Miller; P J Weiss; E C Oldfield; Igor Grant
Neurocognitive impairment in human immunodeficiency virus infection is correlated with sexually transmitted disease history.
Sexually transmitted diseases 1997;24(7):398-401.
1997: L Li; Jay A Nelson; William J Britt
Glycoprotein H-related complexes of human cytomegalovirus: identification of a third protein in the gCIII complex.
Journal of virology 1997;71(4):3090-7.
1997: Persephone Borrow; Hanna Lewicki; X Wei; Marc S Horwitz; N Peffer; H Meyers; Jay A Nelson; Jean Edouard Gairin; B H Hahn; Michael B A Oldstone; G M Shaw
Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus.
Nature medicine 1997;3(2):205-11.
1997: JF Arevalo; J I Quiceno; R F García; J Allen McCutchan; D Munguia; Jay A Nelson; William R Freeman
Retinal findings and characteristics in AIDS patients with systemic Mycobacterium avium-intracellulare complex and toxoplasmic encephalitis.
Ophthalmic surgery and lasers 1997;28(1):50-4.
1996: T R Jones; E J Wiertz; L Sun; K N Fish; Jay A Nelson; H L Ploegh
Human cytomegalovirus US3 impairs transport and maturation of major histocompatibility complex class I heavy chains.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(21):11327-33.
1996: Jacques G Prudhomme; Irwin W Sherman; K M Land; Ashlee V Moses; S Stenglein; Jay A Nelson
Studies of Plasmodium falciparum cytoadherence using immortalized human brain capillary endothelial cells.
International journal for parasitology 1996;26(6):647-55.
1996: Ashlee V Moses; S G Stenglein; J G Strussenberg; K Wehrly; B Chesebro; Jay A Nelson
Sequences regulating tropism of human immunodeficiency virus type 1 for brain capillary endothelial cells map to a unique region on the viral genome.
Journal of virology 1996;70(6):3401-6.
1996: J F Baskar; Patsy P Smith; Gary Ciment; S Hoffmann; C Tucker; D J Tenney; A M Colberg-Poley; Jay A Nelson; Peter Ghazal
Developmental analysis of the cytomegalovirus enhancer in transgenic animals.
Journal of virology 1996;70(5):3215-26.
1996: J F Baskar; Patsy P Smith; G Nilaver; R A Jupp; S Hoffmann; N J Peffer; D J Tenney; A M Colberg-Poley; Peter Ghazal; Jay A Nelson
The enhancer domain of the human cytomegalovirus major immediate-early promoter determines cell type-specific expression in transgenic mice.
Journal of virology 1996;70(5):3207-14.
1996: Kenneth N Fish; W Britt; Jay A Nelson
A novel mechanism for persistence of human cytomegalovirus in macrophages.
Journal of virology 1996;70(3):1855-62.
1996: Ashlee V Moses; S Williams; M L Heneveld; J Strussenberg; M Rarick; M Loveless; Grover C Bagby; Jay A Nelson
Human immunodeficiency virus infection of bone marrow endothelium reduces induction of stromal hematopoietic growth factors.
Blood 1996;87(3):919-25.
1996: Ashlee V Moses; S G Stenglein; Jay A Nelson
HIV infection of the brain microvasculature and its contribution to the AIDS dementia complex.
Journal of neuro-AIDS 1996;1(1):85-99.
1995: M J Margolis; S Pajovic; E L Wong; M Wade; R Jupp; Jay A Nelson; JC Azizkhan
Interaction of the 72-kilodalton human cytomegalovirus IE1 gene product with E2F1 coincides with E2F-dependent activation of dihydrofolate reductase transcription.
Journal of virology 1995;69(12):7759-67.
1995: Bao-Ling Adam; T Y Jervey; C P Kohler; G L Wright; Jay A Nelson; Richard M Stenberg
The human cytomegalovirus UL98 gene transcription unit overlaps with the pp28 true late gene (UL99) and encodes a 58-kilodalton early protein.
Journal of virology 1995;69(9):5304-10.
1995: Julie A Kerry; A Sehgal; S W Barlow; V J Cavanaugh; K Fish; Jay A Nelson; Richard M Stenberg
Isolation and characterization of a low-abundance splice variant from the human cytomegalovirus major immediate-early gene region.
Journal of virology 1995;69(6):3868-72.
1995: Kenneth N Fish; A S Depto; Ashlee V Moses; W Britt; Jay A Nelson
Growth kinetics of human cytomegalovirus are altered in monocyte-derived macrophages.
Journal of virology 1995;69(6):3737-43.
1995: Kenneth N Fish; S G Stenglein; C Ibanez; Jay A Nelson
Cytomegalovirus persistence in macrophages and endothelial cells.
Scandinavian journal of infectious diseases. Supplementum 1995;99():34-40.
1994: Cristian L Achim; R M Nagra; R Wang; Jay A Nelson; C A Wiley
Detection of cytomegalovirus in cerebrospinal fluid autopsy specimens from AIDS patients.
The Journal of infectious diseases 1994;169(3):623-7.
1994: Ashlee V Moses; C Ibanez; R Gaynor; Peter Ghazal; Jay A Nelson
Differential role of long terminal repeat control elements for the regulation of basal and Tat-mediated transcription of the human immunodeficiency virus in stimulated and unstimulated primary human macrophages.
Journal of virology 1994;68(1):298-307.
1994: Ashlee V Moses; Jay A Nelson
HIV infection of human brain capillary endothelial cells--implications for AIDS dementia.
Advances in neuroimmunology 1994;4(3):239-47.
1993: J Wu; R Jupp; Richard M Stenberg; Jay A Nelson; Peter Ghazal
Site-specific inhibition of RNA polymerase II preinitiation complex assembly by human cytomegalovirus IE86 protein.
Journal of virology 1993;67(12):7547-55.
1993: R Jupp; S Hoffmann; Richard M Stenberg; Jay A Nelson; Peter Ghazal
Human cytomegalovirus IE86 protein interacts with promoter-bound TATA-binding protein via a specific region distinct from the autorepression domain.
Journal of virology 1993;67(12):7539-46.
1993: Ashlee V Moses; F E Bloom; C. David Pauza; Jay A Nelson
Human immunodeficiency virus infection of human brain capillary endothelial cells occurs via a CD4/galactosylceramide-independent mechanism.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(22):10474-8.
1993: R Jupp; S Hoffmann; A Depto; Richard M Stenberg; Peter Ghazal; Jay A Nelson
Direct interaction of the human cytomegalovirus IE86 protein with the cis repression signal does not preclude TBP from binding to the TATA box.
Journal of virology 1993;67(9):5595-604.
1993: R Jupp; O Flores; Jay A Nelson; Peter Ghazal
The DNA-binding subunit of human transcription factor IID can interact with the TATA box as a multimer.
The Journal of biological chemistry 1993;268(22):16105-8.
1993: Richard Spaete; K Perot; P I Scott; Jay A Nelson; M F Stinski; C Pachl
Coexpression of truncated human cytomegalovirus gH with the UL115 gene product or the truncated human fibroblast growth factor receptor results in transport of gH to the cell surface.
Virology 1993;193(2):853-61.
1992: H Smith; Jay A Nelson; C G Gahmberg; I Crandall; Irwin W Sherman
Plasmodium falciparum: cytoadherence of malaria-infected erythrocytes to human brain capillary and umbilical vein endothelial cells--a comparative study of adhesive ligands.
Experimental parasitology 1992;75(3):269-80.
1992: E Baracchini; E Glezer; K Fish; Richard M Stenberg; Jay A Nelson; Peter Ghazal
An isoform variant of the cytomegalovirus immediate-early auto repressor functions as a transcriptional activator.
Virology 1992;188(2):518-29.
1991: Peter Ghazal; J Young; E Giulietti; C DeMattei; J Garcia; R Gaynor; Richard M Stenberg; Jay A Nelson
A discrete cis element in the human immunodeficiency virus long terminal repeat mediates synergistic trans activation by cytomegalovirus immediate-early proteins.
Journal of virology 1991;65(12):6735-42.
1991: C E Ibanez; R Schrier; Peter Ghazal; C Wiley; Jay A Nelson
Human cytomegalovirus productively infects primary differentiated macrophages.
Journal of virology 1991;65(12):6581-8.
1991: P Ghazal; Jay A Nelson
Enhancement of RNA polymerase II initiation complexes by a novel DNA control domain downstream from the cap site of the cytomegalovirus major immediate-early promoter.
Journal of virology 1991;65(5):2299-307.
1991: C A Wiley; R D Schrier; M Morey; Cristian L Achim; J C Venable; Jay A Nelson
Pathogenesis of HIV encephalitis.
Acta pathologica japonica 1991;41(3):192-6.
1991: C Reynolds-Kohler; C Wiley; Jay A Nelson
Cells infected by human immunodeficiency virus in vivo.
Advances in experimental medicine and biology 1991;300():27-44.
1990: L Pearson; J Garcia; F Wu; N Modesti; Jay A Nelson; Richard B Gaynor
A transdominant tat mutant that inhibits tat-induced gene expression from the human immunodeficiency virus long terminal repeat.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(13):5079-83.
1990: R D Schrier; J Allen McCutchan; J C Venable; Jay A Nelson; C A Wiley
T-cell-induced expression of human immunodeficiency virus in macrophages.
Journal of virology 1990;64(7):3280-8.
1990: Janet L Lathey; C A Wiley; M A Verity; Jay A Nelson
Cultured human brain capillary endothelial cells are permissive for infection by human cytomegalovirus.
Virology 1990;176(1):266-73.
1990: J M Löhr; Jay A Nelson; M B Oldstone
Is herpes simplex virus associated with peptic ulcer disease?
Journal of virology 1990;64(5):2168-74.
1990: Richard M Stenberg; J Fortney; S W Barlow; B P Magrane; Jay A Nelson; Peter Ghazal
Promoter-specific trans activation and repression by human cytomegalovirus immediate-early proteins involves common and unique protein domains.
Journal of virology 1990;64(4):1556-65.
1990: S H Lewis; C Reynolds-Kohler; Harold E Fox; Jay A Nelson
HIV-1 in trophoblastic and villous Hofbauer cells, and haematological precursors in eight-week fetuses.
Lancet 1990;335(8689):565-8.
1990: C A Wiley; A L Belman; dennis dickson; Arye Rubinstein; Jay A Nelson
Human immunodeficiency virus within the brains of children with AIDS.
Clinical neuropathology 1990;9(1):1-6.
1990: Janet L Lathey; J M Agosti; Jay A Nelson; L Corey; S A Gregory; James Morrissey; T S Edgington; M B Oldstone
A selective defect in tissue factor mRNA expression in monocytes from AIDS patients.
Clinical immunology and immunopathology 1990;54(1):1-13.
1990: Jay A Nelson; P Ghazal; C A Wiley
Role of opportunistic viral infections in AIDS.
AIDS (London, England) 1990;4(1):1-10.
1990: C A Wiley; Jay A Nelson
Human immunodeficiency virus: infection of the nervous system.
Current topics in microbiology and immunology 1990;160():157-72.
1990: Jay A Nelson; J W Gnann; P Ghazal
Regulation and tissue-specific expression of human cytomegalovirus.
Current topics in microbiology and immunology 1990;154():75-100.
1990: P Ghazal; H Lubon; C Reynolds-Kohler; L Hennighausen; Jay A Nelson
Interactions between cellular regulatory proteins and a unique sequence region in the human cytomegalovirus major immediate-early promoter.
Virology 1990;174(1):18-25.
1989: M Schiødt; Deborah Greenspan; Jay A Levy; Jay A Nelson; David Chernoff; H Hollander; John Greenspan
Does HIV cause salivary gland disease?
AIDS (London, England) 1989;3(12):819-22.
1989: M Schiødt; Deborah Greenspan; T E Daniels; Jay A Nelson; P J Leggott; D W Wara; John Greenspan
Parotid gland enlargement and xerostomia associated with labial sialadenitis in HIV-infected patients.
Journal of autoimmunity 1989;2(4):415-25.
1989: C P Chang; D H Vesole; Jay A Nelson; M B Oldstone; Mark F Stinski
Identification and expression of a human cytomegalovirus early glycoprotein.
Journal of virology 1989;63(8):3330-7.
1989: Richard M Stenberg; A S Depto; J Fortney; Jay A Nelson
Regulated expression of early and late RNAs and proteins from the human cytomegalovirus immediate-early gene region.
Journal of virology 1989;63(6):2699-708.
1989: H Lubon; P Ghazal; Lothar Hennighausen; C Reynolds-Kohler; C Lockshin; Jay A Nelson
Cell-specific activity of the modulator region in the human cytomegalovirus major immediate-early gene.
Molecular and cellular biology 1989;9(3):1342-5.
1989: R D Schrier; J W Gnann; R Landes; C Lockshin; D Richman; A McCutchan; C Kennedy; M B Oldstone; Jay A Nelson
T cell recognition of HIV synthetic peptides in a natural infection.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(4):1166-76.
1989: J M Löhr; Jay A Nelson; M B Oldstone
Herpes simplex virus is associated with peptic ulcer disease.
Transactions of the Association of American Physicians 1989;102():213-23.
1988: H Lubon; P Ghazal; Jay A Nelson; Lothar Hennighausen
Cell-specific activity of the human immunodeficiency virus enhancer repeat in vitro.
AIDS research and human retroviruses 1988;4(5):381-91.
1988: C A Wiley; Jay A Nelson
Role of human immunodeficiency virus and cytomegalovirus in AIDS encephalitis.
The American journal of pathology 1988;133(1):73-81.
1988: R D Schrier; J W Gnann; A J Langlois; K Shriver; Jay A Nelson; M B Oldstone
B- and T-lymphocyte responses to an immunodominant epitope of human immunodeficiency virus.
Journal of virology 1988;62(8):2531-6.
1988: J W Gnann; J Ahlmén; C Svalander; L Olding; M B Oldstone; Jay A Nelson
Inflammatory cells in transplanted kidneys are infected by human cytomegalovirus.
The American journal of pathology 1988;132(2):239-48.
1988: Jay A Nelson; C Reynolds-Kohler; M B Oldstone; C A Wiley
HIV and HCMV coinfect brain cells in patients with AIDS.
Virology 1988;165(1):286-90.
1988: Jay A Nelson; C A Wiley; C Reynolds-Kohler; C E Reese; W Margaretten; J A Levy
Human immunodeficiency virus detected in bowel epithelium from patients with gastrointestinal symptoms.
Lancet 1988;1(8580):259-62.
1988: Terumi Kohwi-Shigematsu; Jay A Nelson
The chemical carcinogen, chloroacetaldehyde, modifies a specific site within the regulatory sequence of human cytomegalovirus major immediate early gene in vivo.
Molecular carcinogenesis 1988;1(1):20-5.
1988: C A Wiley; Marjorie R Grafe; C Kennedy; Jay A Nelson
Human immunodeficiency virus (HIV) and JC virus in acquired immune deficiency syndrome (AIDS) patients with progressive multifocal leukoencephalopathy.
Acta neuropathologica 1988;76(4):338-46.
1988: R S Fujinami; Jay A Nelson; L Walker; M B Oldstone
Sequence homology and immunologic cross-reactivity of human cytomegalovirus with HLA-DR beta chain: a means for graft rejection and immunosuppression.
Journal of virology 1988;62(1):100-5.
1987: Jay A Nelson; C Reynolds-Kohler; B A Smith
Negative and positive regulation by a short segment in the 5'-flanking region of the human cytomegalovirus major immediate-early gene.
Molecular and cellular biology 1987;7(11):4125-9.
1987: J W Gnann; Joseph B McCormick; S Mitchell; Jay A Nelson; M B Oldstone
Synthetic peptide immunoassay distinguishes HIV type 1 and HIV type 2 infections.
Science (New York, N.Y.) 1987;237(4820):1346-9.
1987: J W Gnann; Jay A Nelson; M B Oldstone
Fine mapping of an immunodominant domain in the transmembrane glycoprotein of human immunodeficiency virus.
Journal of virology 1987;61(8):2639-41.
1987: J W Gnann; P L Schwimmbeck; Jay A Nelson; A B Truax; M B Oldstone
Diagnosis of AIDS by using a 12-amino acid peptide representing an immunodominant epitope of the human immunodeficiency virus.
The Journal of infectious diseases 1987;156(2):261-7.
1986: C A Wiley; R D Schrier; Jay A Nelson; P W Lampert; M B Oldstone
Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(18):7089-93.
1986: C A Wiley; R D Schrier; F J Denaro; Jay A Nelson; P W Lampert; M B Oldstone
Localization of cytomegalovirus proteins and genome during fulminant central nervous system infection in an AIDS patient.
Journal of neuropathology and experimental neurology 1986;45(2):127-39.
1986: Jay A Nelson; M Groudine
Transcriptional regulation of the human cytomegalovirus major immediate-early gene is associated with induction of DNase I-hypersensitive sites.
Molecular and cellular biology 1986;6(2):452-61.
1985: R D Schrier; Jay A Nelson; M B Oldstone
Detection of human cytomegalovirus in peripheral blood lymphocytes in a natural infection.
Science (New York, N.Y.) 1985;230(4729):1048-51.
1984: D A Galloway; Jay A Nelson; J K McDougall
Small fragments of herpesvirus DNA with transforming activity contain insertion sequence-like structures.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(15):4736-40.
1984: James K McDougall; Jay A Nelson; D Myerson; AM Beckmann; D A Galloway
HSV, CMV, and HPV in human neoplasia.
The Journal of investigative dermatology 1984;83(1 Suppl):72s-76s.
1984: D Myerson; R C Hackman; Jay A Nelson; D C Ward; J K McDougall
Widespread presence of histologically occult cytomegalovirus.
Human pathology 1984;15(5):430-9.
1984: G Jahn; E Knust; H Schmolla; T Sarre; Jay A Nelson; J K McDougall; Bernhard Fleckenstein
Predominant immediate-early transcripts of human cytomegalovirus AD 169.
Journal of virology 1984;49(2):363-70.
1984: Jay A Nelson; Bernhard Fleckenstein; G Jahn; D A Galloway; J K McDougall
Structure of the transforming region of human cytomegalovirus AD169.
Journal of virology 1984;49(1):109-15.
1982: Jay A Nelson; Bernhard Fleckenstein; D A Galloway; J K McDougall
Transformation of NIH 3T3 cells with cloned fragments of human cytomegalovirus strain AD169.
Journal of virology 1982;43(1):83-91.