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John Neoptolemos

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Cosmeri Rizzato; Pavel Soucek; Renata Talar-Wojnarowska; Pavel Vodicka; Ludmila Vodickova; Jens Werner; Franco Bambi; Andrea S Bauer; Markus W Büchler; Peter Bugert; Daniele Campa; Gabriele Capurso; Nathalia Giese; William Greenhalf; Anette Heller; Jörg D Hoheisel; Krzysztof Jamroziak; Tim J Key; Kay-Tee Khaw; Stefano Landi; Beatrice Mohelnikova-Duchonova; John P Neoptolemos; Raffaele Pezzilli; Federico Canzian
ABO blood groups and pancreatic cancer risk and survival: results from the PANcreatic Disease ReseArch (PANDoRA) consortium.
Sarah Tonack; T Cox; Victoria Louise Elliott; Helmut Friess; William Greenhalf; Rosalind E Jenkins; C Jenkinson; Neil R Kitteringham; C W Michalski; John P Neoptolemos; V Shaw; Eithne Costello
iTRAQ reveals candidate pancreatic cancer serum biomarkers: influence of obstructive jaundice on their performance.
Daniele Campa; Franco Bambi; Andrea S Bauer; Markus W Büchler; Peter Bugert; Gabriele Capurso; Eithne Costello; Gianfranco Delle Fave; Maria Gazouli; Nathalia Giese; Anette Heller; Jörg D Hoheisel; Krzysztof Jamroziak; Timothy J Key; Kay-Tee Khaw; Stefano Landi; Beatrice Mohelnikova-Duchonova; John P Neoptolemos; Raffaele Pezzilli; Cosmeri Rizzato; Pavel Soucek; Renata Talar-Wojnarowska; George Theodoropoulos; Pavel Vodicka; Ludmila Vodickova; Jens Werner; Federico Canzian
Lack of replication of seven pancreatic cancer susceptibility loci identified in two Asian populations.

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All Publications

2013: Cosmeri Rizzato; Pavel Soucek; Renata Talar-Wojnarowska; Pavel Vodicka; Ludmila Vodickova; Jens Werner; Franco Bambi; Andrea S Bauer; Markus W Büchler; Peter Bugert; Daniele Campa; Gabriele Capurso; Nathalia Giese; William Greenhalf; Anette Heller; Jörg D Hoheisel; Krzysztof Jamroziak; Tim J Key; Kay-Tee Khaw; Stefano Landi; Beatrice Mohelnikova-Duchonova; John P Neoptolemos; Raffaele Pezzilli; Federico Canzian
ABO blood groups and pancreatic cancer risk and survival: results from the PANcreatic Disease ReseArch (PANDoRA) consortium.
Oncology reports 2013;29(4):1637-44.
2013: Sarah Tonack; T Cox; Victoria Louise Elliott; Helmut Friess; William Greenhalf; Rosalind E Jenkins; C Jenkinson; Neil R Kitteringham; C W Michalski; John P Neoptolemos; V Shaw; Eithne Costello
iTRAQ reveals candidate pancreatic cancer serum biomarkers: influence of obstructive jaundice on their performance.
British journal of cancer 2013;108(9):1846-53.
2013: Daniele Campa; Franco Bambi; Andrea S Bauer; Markus W Büchler; Peter Bugert; Gabriele Capurso; Eithne Costello; Gianfranco Delle Fave; Maria Gazouli; Nathalia Giese; Anette Heller; Jörg D Hoheisel; Krzysztof Jamroziak; Timothy J Key; Kay-Tee Khaw; Stefano Landi; Beatrice Mohelnikova-Duchonova; John P Neoptolemos; Raffaele Pezzilli; Cosmeri Rizzato; Pavel Soucek; Renata Talar-Wojnarowska; George Theodoropoulos; Pavel Vodicka; Ludmila Vodickova; Jens Werner; Federico Canzian
Lack of replication of seven pancreatic cancer susceptibility loci identified in two Asian populations.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2013;22(2):320-3.
2013: Sivaramakrishna Rachakonda; Cosmeri Rizzato; Aldo Scarpa; Michaela Schanne; Jens Werner; Huaping Xie; John P Neoptolemos; Andrea S Bauer; Stefania Beghelli; Markus Büchler; Daniele Campa; Federico Canzian; Eithne Costello; Nathalia Giese; William Greenhalf; Anette Heller; Kari Hemminki; Jörg D Hoheisel; Rajiv Kumar
Somatic mutations in exocrine pancreatic tumors: association with patient survival.
PloS one 2013;8(4):e60870.
2012: Eithne Costello; William Greenhalf; John P Neoptolemos
New biomarkers and targets in pancreatic cancer and their application to treatment.
Nature reviews. Gastroenterology & hepatology 2012;9(8):435-44.
2012: John P Neoptolemos; Attila Oláh; Daniel H Palmer; Charlotte L Rawcliffe; Andrew G Scarfe; David Smith; Niall C Tebbutt; Juan W Valle; Caroline S Verbeke; Alan Anthoney; Markus W Büchler; Fiona Campbell; Ross Carter; Richard M Charnley; Trevor F Cox; Christos Dervenis; Paula Ghaneh; Bengt Glimelius; Christopher M Halloran; François Lacaine; Markus M Lerch; Alexander C McDonald; Mark R Middleton; Malcolm J Moore
Effect of adjuvant chemotherapy with fluorouracil plus folinic acid or gemcitabine vs observation on survival in patients with resected periampullary adenocarcinoma: the ESPAC-3 periampullary cancer randomized trial.
JAMA : the journal of the American Medical Association 2012;308(2):147-56.
2012: Paul D Sykes; John P Neoptolemos; Eithne Costello; Christopher M Halloran
Nanotechnology advances in upper gastrointestinal, liver and pancreatic cancer.
Expert review of gastroenterology & hepatology 2012;6(3):343-56.
2012: David A Tuveson; John P Neoptolemos
Understanding metastasis in pancreatic cancer: a call for new clinical approaches.
Cell 2012;148(1-2):21-3.
2012: Catrin Tudur Smith; Deborah D Stocken; Trevor Cox; David Cunningham; Janet Dunn; Paula Ghaneh; John P Neoptolemos
The value of source data verification in a cancer clinical trial.
PloS one 2012;7(12):e51623.
2012: Asma Sultana; Trevor Cox; Paula Ghaneh; John P Neoptolemos
Adjuvant therapy for pancreatic cancer.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2012;196():65-88.
2011: Philip J Starkey Lewis; David J Webb; Vivien Platt; Kenneth J Simpson; Daniel J Antoine; Eithne M Costello; Darren G N Craig; James Dear; Neeraj Dhaun; Neil S French; Chris Goldring; Jonathan Moggs; John P Neoptolemos; B Kevin Park
Circulating microRNAs as potential markers of human drug-induced liver injury.
Hepatology (Baltimore, Md.) 2011;54(5):1767-76.
2011: John P Neoptolemos
Adjuvant treatment of pancreatic cancer.
European journal of cancer (Oxford, England : 1990) 2011;47 Suppl 3():S378-80.
2011: E Costello; John P Neoptolemos
Enhancing the translation of cancer biomarkers.
The British journal of surgery 2011;98(8):1039-40.
2011: David M Booth; John A Murphy; Rajarshi Mukherjee; Muhammad Awais; John P Neoptolemos; Oleg V Gerasimenko; Alexei V Tepikin; Ole H Petersen; Robert Sutton; David N Criddle
Reactive oxygen species induced by bile acid induce apoptosis and protect against necrosis in pancreatic acinar cells.
Gastroenterology 2011;140(7):2116-25.
2011: Markus K Diener; Emre Gazyakan; Inga Rossion; Jörg Kleeff; Matthias Glanemann; Giovanni Butturini; Ales Tomazic; Christiane J Bruns; Olivier R C Busch; Stefan Farkas; Orlin Belyaev; John P Neoptolemos; Christopher Halloran; Tobias Keck; Marco Niedergethmann; Klaus Gellert; Helmut Witzigmann; Otto Kollmar; Peter Langer; Ulrich Steger; Jens Neudecker; Frederik Berrevoet; Silke Ganzera; Markus M Heiss; Steffen P Luntz; Thomas Bruckner; Meinhard Kieser; Markus W Büchler
Efficacy of stapler versus hand-sewn closure after distal pancreatectomy (DISPACT): a randomised, controlled multicentre trial.
Lancet 2011;377(9776):1514-22.
2011: R A Smith; J Tang; Catrin Tudur Smith; John P Neoptolemos; Paula Ghaneh
Meta-analysis of immunohistochemical prognostic markers in resected pancreatic cancer.
British journal of cancer 2011;104(9):1440-51.
2011: Eithne Costello; John P Neoptolemos
Pancreatic cancer in 2010: new insights for early intervention and detection.
Nature reviews. Gastroenterology & hepatology 2011;8(2):71-3.
2011: Cosmeri Rizzato; Michaela Schanné; Afshan Siddiq; Jens Werner; Andrea Bauer; Markus W Büchler; Barbara Burwinkel; Daniele Campa; Eithne Costello; Nathalia Giese; William Greenhalf; Jörg D Hoheisel; Tim J Key; Kay-Tee Khaw; Rajiv Kumar; Justo Lorenzo-Bermejo; John P Neoptolemos; Sivaramakrishna Rachakonda; Federico Canzian
Pancreatic cancer susceptibility loci and their role in survival.
PloS one 2011;6(11):e27921.
2011: Christopher M Halloran; John P Neoptolemos; Michael G T Raraty; Robert Sutton; Seema Chauhan; Trevor F Cox; Paula Ghaneh
Partial pancreatic resection for pancreatic malignancy is associated with sustained pancreatic exocrine failure and reduced quality of life: a prospective study.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2011;11(6):535-45.
2011: Adam Lister; Nedjadi Taoufik; Neil R Kitteringham; Fiona Campbell; Eithne Costello; Bryony Lloyd; Ian M Copple; Samantha Williams; Andrew Owen; John P Neoptolemos; Chris E Goldring; B Kevin Park
Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy.
Molecular cancer 2011;10():37.
2010: Elizabeth M Tweedle; Ilyas Khattak; Chin Wee Ang; Nedjadi Taoufik; Rosalind Jenkins; B Kevin Park; Helen Kalirai; Andrew Dodson; Bahram Azadeh; Monica Terlizzo; Heike Grabsch; Wolfram Mueller; Sun Myint; Peter Clark; Helen Wong; William Greenhalf; John P Neoptolemos; Paul S Rooney; Eithne Costello
Low molecular weight heat shock protein HSP27 is a prognostic indicator in rectal cancer but not colon cancer.
Gut 2010;59(11):1501-10.
2010: John P Neoptolemos; Deborah D Stocken; Claudio Bassi; Paula Ghaneh; David Cunningham; David Goldstein; Robert Padbury; Malcolm J Moore; Steven Gallinger; Christophe Mariette; Moritz Wente; Jakob R Izbicki; Helmut Friess; Markus M Lerch; Christos Dervenis; Attila Oláh; Giovanni Butturini; Ryuichiro Doi; Pehr A Lind; David Smith; Juan W Valle; Daniel H Palmer; John A Buckels; Joyce Thompson; Colin J McKay; Charlotte L Rawcliffe; Markus W Büchler
Adjuvant chemotherapy with fluorouracil plus folinic acid vs gemcitabine following pancreatic cancer resection: a randomized controlled trial.
JAMA : the journal of the American Medical Association 2010;304(10):1073-81.
2010: Chin Wee Ang; Nedjadi Taoufik; Adnan A Sheikh; Elizabeth M Tweedle; Sarah Tonack; Sailish Honap; Rosalind E Jenkins; B Kevin Park; Irmgard Schwarte-Waldhoff; Ilyas Khattak; Bahram Azadeh; Andrew Dodson; Helen Kalirai; John P Neoptolemos; Paul S Rooney; Eithne Costello
Smad4 loss is associated with fewer S100A8-positive monocytes in colorectal tumors and attenuated response to S100A8 in colorectal and pancreatic cancer cells.
Carcinogenesis 2010;31(9):1541-51.
2010: S Ripka; A Neesse; J Riedel; E Bug; Achim Aigner; R Poulsom; S Fulda; John P Neoptolemos; William Greenhalf; Peter Barth; Thomas M Gress; P Michl
CUX1: target of Akt signalling and mediator of resistance to apoptosis in pancreatic cancer.
Gut 2010;59(8):1101-10.
2010: Christoph Schröder; Anette Jacob; Sarah Tonack; Tomasz P Radon; Martin Sill; Manuela Zucknick; Sven Rüffer; Eithne Costello; John P Neoptolemos; Tatjana Crnogorac-Jurcevic; Andrea Bauer; Kurt Fellenberg; Jörg D Hoheisel
Dual-color proteomic profiling of complex samples with a microarray of 810 cancer-related antibodies.
Molecular & cellular proteomics : MCP 2010;9(6):1271-80.
2010: John P Neoptolemos; Christopher M Halloran
Surgical oncology: PBD-better stents in specialized centers are needed.
Nature reviews. Clinical oncology 2010;7(5):244-6.
2010: Christopher J Grocock; Vinciane Rebours; Myriam N Delhaye; Ake Andrén-Sandberg; Frank Ulrich Weiss; Roger Mountford; Matthew J Harcus; Edyta Niemczyck; Louis J Vitone; Susanna Dodd; Maiken Thyregod Jørgensen; Rudolf W Ammann; Ove Schaffalitzky de Muckadell; Jane V Butler; Phillip Burgess; Bronwyn Kerr; Richard Charnley; Robert Sutton; Michael G T Raraty; Jacques Devière; david whitcomb; John P Neoptolemos; Philippe Lévy; Markus M Lerch; William Greenhalf
The variable phenotype of the p.A16V mutation of cationic trypsinogen (PRSS1) in pancreatitis families.
Gut 2010;59(3):357-63.
2010: Amy Thomas; Khaled Dajani; John P Neoptolemos; Paula Ghaneh
Adjuvant therapy in pancreatic cancer.
Digestive diseases (Basel, Switzerland) 2010;28(4-5):684-92.
2010: Sarah Tonack; John P Neoptolemos; Eithne Costello
Analysis of serum proteins by LC-MS/MS.
Methods in molecular biology (Clifton, N.J.) 2010;658():281-91.
2009: Sarah Tonack; Mark Aspinall-O'Dea; Rosalind E Jenkins; Victoria Elliot; Seonaid Murray; Catherine S Lane; Neil R Kitteringham; John P Neoptolemos; Eithne Costello
A technically detailed and pragmatic protocol for quantitative serum proteomics using iTRAQ.
Journal of proteomics 2009;73(2):352-6.
2009: David Cunningham; Ian Chau; Deborah D Stocken; Juan W Valle; David Smith; William Steward; Peter G Harper; Janet Dunn; Catrin Tudur Smith; Julia West; Stephen Falk; Adrian Crellin; Fawzi Adab; Joyce Thompson; Pauline Leonard; Joe Ostrowski; Martin Eatock; Werner Scheithauer; Richard Herrmann; John P Neoptolemos
Phase III randomized comparison of gemcitabine versus gemcitabine plus capecitabine in patients with advanced pancreatic cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(33):5513-8.
2009: Nedjadi Taoufik; Neil R Kitteringham; Fiona Campbell; Rosalind E Jenkins; B Kevin Park; P Navarro; F Ashcroft; Alexei V Tepikin; John P Neoptolemos; Eithne Costello
S100A6 binds to annexin 2 in pancreatic cancer cells and promotes pancreatic cancer cell motility.
British journal of cancer 2009;101(7):1145-54.
2009: Fiona Campbell; Richard A Smith; Philip Whelan; Robert Sutton; Michael Raraty; John P Neoptolemos; Paula Ghaneh
Classification of R1 resections for pancreatic cancer: the prognostic relevance of tumour involvement within 1 mm of a resection margin.
Histopathology 2009;55(3):277-83.
2009: Ross Carter; Deborah D Stocken; Paula Ghaneh; Simon R Bramhall; Attila Olah; Deszo Kelemen; Claudio Bassi; Helmut Friess; Christo Dervenis; Nigel Spry; Markus W Büchler; John P Neoptolemos
Longitudinal quality of life data can provide insights on the impact of adjuvant treatment for pancreatic cancer-Subset analysis of the ESPAC-1 data.
International journal of cancer. Journal international du cancer 2009;124(12):2960-5.
2009: Richard A Smith; L Bosonnet; Michael G T Raraty; Robert Sutton; John P Neoptolemos; Fiona Campbell; Paula Ghaneh
Preoperative platelet-lymphocyte ratio is an independent significant prognostic marker in resected pancreatic ductal adenocarcinoma.
American journal of surgery 2009;197(4):466-72.
2009: John P Neoptolemos; Deborah D Stocken; Catrin Tudur Smith; Claudio Bassi; Paula Ghaneh; E Owen; M Moore; R Padbury; R Doi; D Smith; Markus W Büchler
Adjuvant 5-fluorouracil and folinic acid vs observation for pancreatic cancer: composite data from the ESPAC-1 and -3(v1) trials.
British journal of cancer 2009;100(2):246-50.
2009: Nicole Sakka; Richard A Smith; Philip Whelan; Paula Ghaneh; Robert Sutton; Michael G T Raraty; Fiona Campbell; John P Neoptolemos
A preoperative prognostic score for resected pancreatic and periampullary neuroendocrine tumours.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2009;9(5):670-6.
2009: Sarah Tonack; Mark Aspinall-O'Dea; John P Neoptolemos; Eithne Costello
Pancreatic cancer: proteomic approaches to a challenging disease.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2009;9(5):567-76.
2009: William Greenhalf; C Grocock; M Harcus; John P Neoptolemos
Screening of high-risk families for pancreatic cancer.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2009;9(3):215-22.
2009: Asma Sultana; Susannah Shore; Michael G T Raraty; Sobhan Vinjamuri; Jonathan E Evans; Catrin Tudur Smith; Steven Lane; Seema Chauhan; L Bosonnet; Conall J Garvey; Robert Sutton; John P Neoptolemos; Paula Ghaneh
Randomised Phase I/II trial assessing the safety and efficacy of radiolabelled anti-carcinoembryonic antigen I(131) KAb201 antibodies given intra-arterially or intravenously in patients with unresectable pancreatic adenocarcinoma.
BMC cancer 2009;9():66.
2009: Li Yan; Sarah Tonack; Richard Smith; Susanna Dodd; Rosalind E Jenkins; Neil Kitteringham; William Greenhalf; Paula Ghaneh; John P Neoptolemos; Eithne Costello
Confounding effect of obstructive jaundice in the interpretation of proteomic plasma profiling data for pancreatic cancer.
Journal of proteome research 2009;8(1):142-8.
2008: B Al-Sarireh; Paula Ghaneh; J Gardner-Thorpe; Michael G T Raraty; M Hartley; Robert Sutton; John P Neoptolemos
Complications and follow-up after pancreas-preserving total duodenectomy for duodenal polyps.
The British journal of surgery 2008;95(12):1506-11.
2008: Richard A Smith; K Dajani; S Dodd; P Whelan; Michael G T Raraty; Robert Sutton; Fiona Campbell; John P Neoptolemos; Paula Ghaneh
Preoperative resolution of jaundice following biliary stenting predicts more favourable early survival in resected pancreatic ductal adenocarcinoma.
Annals of surgical oncology 2008;15(11):3138-46.
2008: Paula Ghaneh; E Costello; John P Neoptolemos
Biology and management of pancreatic cancer.
Postgraduate medical journal 2008;84(995):478-97.
2008: John P Neoptolemos
Clinical evidence does not support the use of adjuvant radiotherapy in pancreatic cancer.
Nature clinical practice. Oncology 2008;5(8):431.
2008: John A Murphy; David N Criddle; Mark William Sherwood; Michael Chvanov; Rajarshi Mukherjee; Euan McLaughlin; David Booth; Julia V Gerasimenko; Michael G T Raraty; Paula Ghaneh; John P Neoptolemos; Oleg V Gerasimenko; Alexei V Tepikin; Gary M Green; Joseph R Reeve; Ole H Petersen; Robert Sutton
Direct activation of cytosolic Ca2+ signaling and enzyme secretion by cholecystokinin in human pancreatic acinar cells.
Gastroenterology 2008;135(2):632-41.
2008: Richard A Smith; Paula Ghaneh; Robert Sutton; Michael Raraty; Fiona Campbell; John P Neoptolemos
Prognosis of resected ampullary adenocarcinoma by preoperative serum CA19-9 levels and platelet-lymphocyte ratio.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2008;12(8):1422-8.
2008: Richard A Smith; L Bosonnet; Paula Ghaneh; Robert Sutton; Johnathan Evans; Priya Healey; Conall J Garvey; M Hughes; Michael G T Raraty; Fiona Campbell; John P Neoptolemos
The platelet-lymphocyte ratio improves the predictive value of serum CA19-9 levels in determining patient selection for staging laparoscopy in suspected periampullary cancer.
Surgery 2008;143(5):658-66.
2008: C M Halloran; Paula Ghaneh; Saxon Connor; Robert Sutton; John P Neoptolemos; Michael G T Raraty
Carbohydrate antigen 19.9 accurately selects patients for laparoscopic assessment to determine resectability of pancreatic malignancy.
The British journal of surgery 2008;95(4):453-9.
2008: Paula Ghaneh; R Smith; C Tudor-Smith; Michael G T Raraty; John P Neoptolemos
Neoadjuvant and adjuvant strategies for pancreatic cancer.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2008;34(3):297-305.
2008: Hjalmar C van Santvoort; Thomas L Bollen; Marc G H Besselink; Peter A Banks; Marja A Boermeester; C H J van Eijck; Jonathan Evans; Patrick C Freeny; Lars Grenacher; John J Hermans; Karen D Horvath; David M Hough; Johan S Laméris; Maarten S van Leeuwen; Koenraad J Mortele; John P Neoptolemos; Michael G Sarr; Santhi Swaroop Vege; Jens Werner; Hein G Gooszen
Describing peripancreatic collections in severe acute pancreatitis using morphologic terms: an international interobserver agreement study.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2008;8(6):593-9.
2008: Asma Sultana; Paula Ghaneh; David Cunningham; Naureen Starling; John P Neoptolemos; Catrin Tudur Smith
Gemcitabine based combination chemotherapy in advanced pancreatic cancer-indirect comparison.
BMC cancer 2008;8():192.
2008: R A Smith; L Bosonnet; Paula Ghaneh; Michael G T Raraty; Robert Sutton; Fiona Campbell; John P Neoptolemos
Preoperative CA19-9 levels and lymph node ratio are independent predictors of survival in patients with resected pancreatic ductal adenocarcinoma.
Digestive surgery 2008;25(3):226-32.
2008: Giovanni Butturini; Deborah D Stocken; Moritz Wente; Hans Jeekel; J H G Klinkenbijl; Kåre E Bakkevold; Tadahiro Takada; Hirano Amano; Christos Dervenis; Claudio Bassi; Markus W Büchler; John P Neoptolemos
Influence of resection margins and treatment on survival in patients with pancreatic cancer: meta-analysis of randomized controlled trials.
Archives of surgery (Chicago, Ill. : 1960) 2008;143(1):75-83; discussion 83.
2007: Moritz Wente; Claudio Bassi; Christos Dervenis; Abe Fingerhut; Dirk J Gouma; Jakob R Izbicki; John P Neoptolemos; Robert T Padbury; Michael G Sarr; L William Traverso; Charles J Yeo; Markus W Büchler
Delayed gastric emptying (DGE) after pancreatic surgery: a suggested definition by the International Study Group of Pancreatic Surgery (ISGPS).
Surgery 2007;142(5):761-8.
2007: Kyaw L Aung; David B Smith; John P Neoptolemos
Adjuvant therapy for pancreatic cancer.
Expert opinion on pharmacotherapy 2007;8(15):2533-41.
2007: Randall E Brand; Markus M Lerch; Wendy S Rubinstein; John P Neoptolemos; david whitcomb; Ralph Hruban; Teresa A Brentnall; Henry T Lynch; Marcia Canto
Advances in counselling and surveillance of patients at risk for pancreatic cancer.
Gut 2007;56(10):1460-9.
2007: Paula Ghaneh; Eithne Costello; John P Neoptolemos
Biology and management of pancreatic cancer.
Gut 2007;56(8):1134-52.
2007: Paula Ghaneh; John P Neoptolemos
A new approach to managing intraductal papillary mucinous pancreatic neoplasms.
Gut 2007;56(8):1041-4.
2007: Moritz Wente; Johannes A Veit; Claudio Bassi; Christos Dervenis; Abe Fingerhut; Dirk J Gouma; Jakob R Izbicki; John P Neoptolemos; Robert T Padbury; Michael G Sarr; Charles J Yeo; Markus W Büchler
Postpancreatectomy hemorrhage (PPH): an International Study Group of Pancreatic Surgery (ISGPS) definition.
Surgery 2007;142(1):20-5.
2007: Asma Sultana; Catrin Tudur Smith; David Cunningham; Naureen Starling; John P Neoptolemos; Paula Ghaneh
Meta-analyses of chemotherapy for locally advanced and metastatic pancreatic cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(18):2607-15.
2007: Asma Sultana; Catrin Tudur Smith; D Cunningham; N Starling; D Tait; John P Neoptolemos; Paula Ghaneh
Systematic review, including meta-analyses, on the management of locally advanced pancreatic cancer using radiation/combined modality therapy.
British journal of cancer 2007;96(8):1183-90.
2007: Emily Slater; Vera Amrillaeva; Volker Fendrich; Detlef Bartsch; Julie Earl; Louis J Vitone; John P Neoptolemos; William Greenhalf
Palladin mutation causes familial pancreatic cancer: absence in European families.
PLoS medicine 2007;4(4):e164.
2007: David B Smith; John P Neoptolemos
Capecitabine: an evidence-based review of its effectiveness in the treatment of carcinoma of the pancreas.
Core evidence 2007;2(2):111-9.
2007: C J Grocock; Louis J Vitone; M J Harcus; John P Neoptolemos; Michael G T Raraty; William Greenhalf
Familial pancreatic cancer: a review and latest advances.
Advances in medical sciences 2007;52():37-49.
2007: Paula Ghaneh; Catrin Tudur Smith; John P Neoptolemos
Comment on "adjuvant therapy in pancreatic cancer: a critical appraisal".
Drugs 2007;67(17):2487-90; discussion 2491-3.
2007: Nicholas Alexakis; Martin Lombard; Michael G T Raraty; Paula Ghaneh; Howard Smart; Ian T Gilmore; Johnathan Evans; M Hughes; Conall J Garvey; Robert Sutton; John P Neoptolemos
When is pancreatitis considered to be of biliary origin and what are the implications for management?
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2007;7(2-3):131-41.
2006: AR Latchford; William Greenhalf; Louis J Vitone; John P Neoptolemos; G A Lancaster; R K S Phillips
Peutz-Jeghers syndrome and screening for pancreatic cancer.
The British journal of surgery 2006;93(12):1446-55.
2006: Julie Earl; Li Yan; Louis J Vitone; Janet Risk; Steve J Kemp; Christopher McFaul; John P Neoptolemos; William Greenhalf; Ralf Kress; Mercedes Sina-Frey; Stephan Hahn; Harald Rieder; Detlef K Bartsch
Evaluation of the 4q32-34 locus in European familial pancreatic cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(10):1948-55.
2006: David B Smith; John P Neoptolemos
Capecitabine in carcinoma of the pancreas.
Expert opinion on pharmacotherapy 2006;7(12):1633-9.
2006: Saxon Connor; Michael G T Raraty; John P Neoptolemos; Peter Layer; Michael Rünzi; William M Steinberg; Jamie S Barkin; Edward L Bradley; Eugene P DiMagno
Does infected pancreatic necrosis require immediate or emergency debridement?
Pancreas 2006;33(2):128-34.
2006: William Greenhalf; John P Neoptolemos
Increasing survival rates of patients with pancreatic cancer by earlier identification.
Nature clinical practice. Oncology 2006;3(7):346-7.
2006: Louis J Vitone; William Greenhalf; Nathan Howes; Michael G T Raraty; John P Neoptolemos
Trypsinogen mutations in pancreatic disorders.
Endocrinology and metabolism clinics of North America 2006;35(2):271-87, viii.
2006: Paula Ghaneh; Asma Sultana; Susannah Shore; Deborah D Stocken; John P Neoptolemos
The case for adjuvant chemotherapy in pancreatic cancer.
Best practice & research. Clinical gastroenterology 2006;20(2):383-401.
2006: Louis J Vitone; William Greenhalf; Christopher McFaul; Paula Ghaneh; John P Neoptolemos
The inherited genetics of pancreatic cancer and prospects for secondary screening.
Best practice & research. Clinical gastroenterology 2006;20(2):253-83.
2006: David N Criddle; John Murphy; Gregorio Fistetto; Stephanie L Barrow; Alexei V Tepikin; John P Neoptolemos; Robert Sutton; Ole H Petersen
Fatty acid ethyl esters cause pancreatic calcium toxicity via inositol trisphosphate receptors and loss of ATP synthesis.
Gastroenterology 2006;130(3):781-93.
2006: Christopher McFaul; William Greenhalf; Julie Earl; Nathan Howes; John P Neoptolemos; Ralf Kress; Mercedes Sina-Frey; Harald Rieder; S Hahn; Detlef K Bartsch
Anticipation in familial pancreatic cancer.
Gut 2006;55(2):252-8.
2005: Detlef K Bartsch; Volker Fendrich; Emily P Slater; Mercedes Sina-Frey; Harald Rieder; William Greenhalf; Brunhilde Chaloupka; Stephan Hahn; John P Neoptolemos; Ralf Kress
RNASEL germline variants are associated with pancreatic cancer.
International journal of cancer. Journal international du cancer 2005;117(5):718-22.
2005: Tatjana Crnogorac-Jurcevic; Rathi Gangeswaran; Vipul Bhakta; Gabriele Capurso; Samuel Lattimore; Masanori Akada; Makoto Sunamura; Wendy Prime; Fiona Campbell; Teresa A Brentnall; Eithne Costello; John P Neoptolemos; Nick Lemoine
Proteomic analysis of chronic pancreatitis and pancreatic adenocarcinoma.
Gastroenterology 2005;129(5):1454-63.
2005: Michael G T Raraty; John P Neoptolemos
Managing acute and chronic pancreatitis.
The Practitioner 2005;249(1675):672, 674, 676-8 passim.
2005: Daniel Wolfson; Jamie S Barkin; Suresh T Chari; Jonathan E Clain; Richard H Bell; Nicholas Alexakis; John P Neoptolemos
Management of pancreatic masses.
Pancreas 2005;31(3):203-17.
2005: Jonathan A Cohn; John P Neoptolemos; Jinong Feng; Jin Yan; Zefei Jiang; William Greenhalf; Christopher McFaul; Roger Mountford; Steve S Sommer
Increased risk of idiopathic chronic pancreatitis in cystic fibrosis carriers.
Human mutation 2005;26(4):303-7.
2005: Claudio Bassi; Christos Dervenis; Giovanni Butturini; Abe Fingerhut; Charles Yeo; Jakob Izbicki; John P Neoptolemos; Michael Sarr; William Traverso; Marcus Buchler
Postoperative pancreatic fistula: an international study group (ISGPF) definition.
Surgery 2005;138(1):8-13.
2005: Li Yan; Christopher McFaul; Nathan Howes; Jane Leslie; Gillian Lancaster; Theresa Wong; Jane Threadgold; Jonathan Evans; Ian T Gilmore; Howard Smart; Martin Lombard; John P Neoptolemos; William Greenhalf
Molecular analysis to detect pancreatic ductal adenocarcinoma in high-risk groups.
Gastroenterology 2005;128(7):2124-30.
2005: Christopher M Halloran; Paula Ghaneh; Eithne Costello; John P Neoptolemos
Trials of gene therapy for pancreatic carcinoma.
Current gastroenterology reports 2005;7(3):165-9.
2005: Saxon Connor; Nicholas Alexakis; Michael G T Raraty; Paula Ghaneh; Johnathan Evans; M Hughes; Conall J Garvey; Robert Sutton; John P Neoptolemos
Early and late complications after pancreatic necrosectomy.
Surgery 2005;137(5):499-505.
2005: Deborah D Stocken; M W Büchler; Christos Dervenis; Claudio Bassi; Hans Jeekel; J H G Klinkenbijl; K E Bakkevold; T Takada; H Amano; John P Neoptolemos
Meta-analysis of randomised adjuvant therapy trials for pancreatic cancer.
British journal of cancer 2005;92(8):1372-81.
2005: Dale Vimalachandran; William Greenhalf; Christopher Thompson; Jutta Lüttges; Wendy Prime; Fiona Campbell; Andrew Dodson; Richard Watson; Tatjana Crnogorac-Jurcevic; Nick Lemoine; John P Neoptolemos; Eithne Costello
High nuclear S100A6 (Calcyclin) is significantly associated with poor survival in pancreatic cancer patients.
Cancer research 2005;65(8):3218-25.
2005: Nathan Howes; William Greenhalf; Deborah D Stocken; John P Neoptolemos
Cationic trypsinogen mutations and pancreatitis.
Clinics in laboratory medicine 2005;25(1):39-59.
2005: John P Neoptolemos
Is endoscopic ultrasonography superior to multidetector CT for assessing pancreatic cancer?
Nature clinical practice. Oncology 2005;2(2):78-9.
2005: Nicholas Alexakis; Fiona Campbell; N Eardley; Howard Smart; Conall J Garvey; John P Neoptolemos
T cell lymphoplasmacellular and eosinophilic infiltration of the pancreas with involvement of the gallbladder and duodenum in non-alcoholic duct-destructive chronic pancreatitis.
Langenbeck's archives of surgery / Deutsche Gesellschaft für Chirurgie 2005;390(1):32-8.
2005: Claudio Bassi; Deborah D Stocken; A Olah; Helmut Friess; J A C Buckels; Helen Hickey; Christos Dervenis; Janet A Dunn; Mark Deakin; R Carter; Paula Ghaneh; John P Neoptolemos; M W Buchler
Influence of surgical resection and post-operative complications on survival following adjuvant treatment for pancreatic cancer in the ESPAC-1 randomized controlled trial.
Digestive surgery 2005;22(5):353-63.
2005: Saxon Connor; Michael G T Raraty; Nathan Howes; Johnathan Evans; Paula Ghaneh; Robert Sutton; John P Neoptolemos
Surgery in the treatment of acute pancreatitis--minimal access pancreatic necrosectomy.
Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society 2005;94(2):135-42.
2005: Nicholas Alexakis; John P Neoptolemos
Algorithm for the diagnosis and treatment of acute biliary pancreatitis.
Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society 2005;94(2):124-9.
2005: Saxon Connor; L Bosonnet; Nicholas Alexakis; Michael G T Raraty; Paula Ghaneh; Robert Sutton; John P Neoptolemos
Serum CA19-9 measurement increases the effectiveness of staging laparoscopy in patients with suspected pancreatic malignancy.
Digestive surgery 2005;22(1-2):80-5.
2005: D Lytras; Saxon Connor; L Bosonnet; R Jayan; J Evans; M Hughes; Conall J Garvey; Paula Ghaneh; Robert Sutton; Sobhan Vinjamuri; John P Neoptolemos
Positron emission tomography does not add to computed tomography for the diagnosis and staging of pancreatic cancer.
Digestive surgery 2005;22(1-2):55-61; discussion 62.
2004: Nathan Howes; William Greenhalf; Deborah D Stocken; John P Neoptolemos
Cationic trypsinogen mutations and pancreatitis.
Gastroenterology clinics of North America 2004;33(4):767-87.
2004: Saxon Connor; L Bosonnet; Paula Ghaneh; Nicholas Alexakis; Mark Hartley; Fiona Campbell; Robert Sutton; John P Neoptolemos
Survival of patients with periampullary carcinoma is predicted by lymph node 8a but not by lymph node 16b1 status.
The British journal of surgery 2004;91(12):1592-9.
2004: Nicholas Alexakis; Christopher M Halloran; Michael G T Raraty; Paula Ghaneh; Robert Sutton; John P Neoptolemos
Current standards of surgery for pancreatic cancer.
The British journal of surgery 2004;91(11):1410-27.
2004: Edoardo Missiaglia; Ekaterina Blaveri; Benoit Terris; Yao-He Wang; Eithne Costello; John P Neoptolemos; Tatjana Crnogorac-Jurcevic; Nick Lemoine
Analysis of gene expression in cancer cell lines identifies candidate markers for pancreatic tumorigenesis and metastasis.
International journal of cancer. Journal international du cancer 2004;112(1):100-12.
2004: Robert Grützmann; Christopher McFaul; Detlef K Bartsch; Mercedes Sina-Frey; Harald Rieder; Rainer Koch; Emma McCarthy; William Greenhalf; John P Neoptolemos; Hans-Detlev Saeger; Christian Pilarsky
No evidence for germline mutations of the LKB1/STK11 gene in familial pancreatic carcinoma.
Cancer letters 2004;214(1):63-8.
2004: Paula Ghaneh; John P Neoptolemos
Conclusions from the European Study Group for Pancreatic Cancer adjuvant trial of chemoradiotherapy and chemotherapy for pancreatic cancer.
Surgical oncology clinics of North America 2004;13(4):567-87, vii-viii.
2004: Nicholas Alexakis; Saxon Connor; Paula Ghaneh; Michael G T Raraty; Martin Lombard; Howard Smart; Johnathan Evans; M Hughes; Conall J Garvey; M Goulden; C Parker; Robert Sutton; John P Neoptolemos
Influence of opioid use on surgical and long-term outcome after resection for chronic pancreatitis.
Surgery 2004;136(3):600-8.
2004: Nicholas Alexakis; Robert Sutton; Michael G T Raraty; Saxon Connor; Paula Ghaneh; Mark L Hughes; Conall J Garvey; J C Evans; John P Neoptolemos
Major resection for chronic pancreatitis in patients with vascular involvement is associated with increased postoperative mortality.
The British journal of surgery 2004;91(8):1020-6.
2004: David N Criddle; Michael G T Raraty; John P Neoptolemos; Alexei V Tepikin; Ole H Petersen; Robert Sutton
Ethanol toxicity in pancreatic acinar cells: mediation by nonoxidative fatty acid metabolites.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(29):10738-43.
2004: Christopher M Halloran; Paula Ghaneh; Susannah Shore; William Greenhalf; Lou Zumstein; Deborah Wilson; John P Neoptolemos; Eithne Costello
5-Fluorouracil or gemcitabine combined with adenoviral-mediated reintroduction of p16INK4A greatly enhanced cytotoxicity in Panc-1 pancreatic adenocarcinoma cells.
The journal of gene medicine 2004;6(5):514-25.
2004: Lucie E Jones; Michelle J Humphreys; Fiona Campbell; John P Neoptolemos; Mark T Boyd
Comprehensive analysis of matrix metalloproteinase and tissue inhibitor expression in pancreatic cancer: increased expression of matrix metalloproteinase-7 predicts poor survival.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(8):2832-45.
2004: Michael G T Raraty; Saxon Connor; David N Criddle; Robert Sutton; John P Neoptolemos
Acute pancreatitis and organ failure: pathophysiology, natural history, and management strategies.
Current gastroenterology reports 2004;6(2):99-103.
2004: John P Neoptolemos; Deborah D Stocken; Helmut Friess; Claudio Bassi; Janet A Dunn; Helen Hickey; Hans Beger; Laureano Fernandez-Cruz; Christos Dervenis; François Lacaine; Massimo Falconi; Paolo Pederzoli; Akos Pap; David Spooner; David J Kerr; Markus W Büchler
A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer.
The New England journal of medicine 2004;350(12):1200-10.
2004: Nathan Howes; Markus M Lerch; William Greenhalf; Deborah D Stocken; Ian Ellis; Peter Simon; Kaspar Truninger; Rudolf W Ammann; Giorgio Cavallini; Richard M Charnley; Generoso Uomo; Miriam Delhaye; Julius Spicak; Brendan Drumm; Jan Jansen; Roger Mountford; david whitcomb; John P Neoptolemos
Clinical and genetic characteristics of hereditary pancreatitis in Europe.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2004;2(3):252-61.
2004: H E Doran; L Bosonnet; Saxon Connor; L Jones; Conall J Garvey; M Hughes; Fiona Campbell; Mark Hartley; Paula Ghaneh; John P Neoptolemos; Robert Sutton
Laparoscopy and laparoscopic ultrasound in the evaluation of pancreatic and periampullary tumours.
Digestive surgery 2004;21(4):305-13.
2004: Saxon Connor; Nicholas Alexakis; Timothy J Neal; Michael G T Raraty; Paula Ghaneh; Johnathan Evans; M Hughes; Peter C Rowlands; Conall J Garvey; Robert Sutton; John P Neoptolemos
Fungal infection but not type of bacterial infection is associated with a high mortality in primary and secondary infected pancreatic necrosis.
Digestive surgery 2004;21(4):297-304.
2004: Christopher McFaul; Louis J Vitone; Fiona Campbell; B Azadeh; Mark L Hughes; Conall J Garvey; Paula Ghaneh; John P Neoptolemos
Pancreatic hamartoma.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2004;4(6):533-7; discussion 537-8.
2004: Nicholas Alexakis; Robert Sutton; John P Neoptolemos
Surgical treatment of pancreatic fistula.
Digestive surgery 2004;21(4):262-74.
2004: Saxon Connor; John P Neoptolemos
Laparoscopy is still necessary in the assessment of peri-ampullary neoplasia.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2004;4(5):415-6.
2004: A R Dhebri; Saxon Connor; Fiona Campbell; Paula Ghaneh; Robert Sutton; John P Neoptolemos
Diagnosis, treatment and outcome of pancreatoblastoma.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2004;4(5):441-51; discussion 452-3.
2004: Nicholas Alexakis; Saxon Connor; Paula Ghaneh; Martin Lombard; Howard Smart; Johnathan Evans; M Hughes; Conall J Garvey; Jiten P Vora; Sobhan Vinjamuri; Robert Sutton; John P Neoptolemos
Hereditary pancreatic endocrine tumours.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2004;4(5):417-33; discussion 434-5.
2004: Dale Vimalachandran; Paula Ghaneh; Eithne Costello; John P Neoptolemos
Genetics and prevention of pancreatic cancer.
Cancer control : journal of the Moffitt Cancer Center 2004;11(1):6-14.
2003: Robert Sutton; H E Doran; E M I Williams; Jiten P Vora; Sobhan Vinjamuri; J Evans; Fiona Campbell; Michael G T Raraty; Paula Ghaneh; Mark Hartley; Graeme J Poston; John P Neoptolemos
Surgery for midgut carcinoid.
Endocrine-related cancer 2003;10(4):469-81.
2003: Susannah Shore; Michael G T Raraty; Paula Ghaneh; John P Neoptolemos
Review article: chemotherapy for pancreatic cancer.
Alimentary pharmacology & therapeutics 2003;18(11-12):1049-69.
2003: Saxon Connor; Paula Ghaneh; Michael G T Raraty; Edoardo Rosso; Mark Hartley; Conall J Garvey; M Hughes; Richard G McWilliams; Johnathan Evans; Peter C Rowlands; Robert Sutton; John P Neoptolemos
Increasing age and APACHE II scores are the main determinants of outcome from pancreatic necrosectomy.
The British journal of surgery 2003;90(12):1542-8.
2003: Nicholas Alexakis; Paula Ghaneh; Saxon Connor; Michael G T Raraty; Robert Sutton; John P Neoptolemos
Duodenum- and spleen-preserving total pancreatectomy for end-stage chronic pancreatitis.
The British journal of surgery 2003;90(11):1401-8.
2003: Ali Shekouh; Christopher C Thompson; Wendy Prime; Fiona Campbell; Jane Hamlett; C Simon Herrington; Nick Lemoine; Tatjana Crnogorac-Jurcevic; Markus W Buechler; Helmut Friess; John P Neoptolemos; Stephen R Pennington; Eithne Costello
Application of laser capture microdissection combined with two-dimensional electrophoresis for the discovery of differentially regulated proteins in pancreatic ductal adenocarcinoma.
Proteomics 2003;3(10):1988-2001.
2003: Tatjana Crnogorac-Jurcevic; Edoardo Missiaglia; Ekaterina Blaveri; Rathi Gangeswaran; Melanie Jones; Benoit Terris; Eithne Costello; John P Neoptolemos; Nick Lemoine
Molecular alterations in pancreatic carcinoma: expression profiling shows that dysregulated expression of S100 genes is highly prevalent.
The Journal of pathology 2003;201(1):63-74.
2003: Michael G T Raraty; John P Neoptolemos
Compartments that cause the real damage in severe acute pancreatitis.
American journal of respiratory and critical care medicine 2003;168(2):141-2.
2003: Madhav Bhatia; A E I Proudfoot; Timothy Wells; Stephen E Christmas; John P Neoptolemos; John Slavin
Treatment with Met-RANTES reduces lung injury in caerulein-induced pancreatitis.
The British journal of surgery 2003;90(6):698-704.
2003: John P Neoptolemos; D Cunningham; Helmut Friess; Claudio Bassi; Deborah D Stocken; D M Tait; Janet A Dunn; Christos Dervenis; François Lacaine; Helen Hickey; Michael G T Raraty; Paula Ghaneh; Markus W Büchler
Adjuvant therapy in pancreatic cancer: historical and current perspectives.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2003;14(5):675-92.
2003: Madhav Bhatia; John Slavin; Yuqing Cao; Allan I Basbaum; John P Neoptolemos
Preprotachykinin-A gene deletion protects mice against acute pancreatitis and associated lung injury.
American journal of physiology. Gastrointestinal and liver physiology 2003;284(5):G830-6.
2003: John P Neoptolemos; Michael G T Raraty; Paula Ghaneh; Helen Hickey; Deborah D Stocken; Janet A Dunn; Helmut Friess; Markus W Büchler
[Adjuvant and additive therapy for cancer of the pancreas].
Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen 2003;74(3):191-201.
2003: James D Evans; Philip A Cornford; Andrew Dodson; John P Neoptolemos; Christopher S Foster
Expression patterns of protein kinase C isoenzymes are characteristically modulated in chronic pancreatitis and pancreatic cancer.
American journal of clinical pathology 2003;119(3):392-402.
2003: Stephan Hahn; Bill Greenhalf; Ian Ellis; Mercedes Sina-Frey; Harald Rieder; Birgit Korte; Berthold Gerdes; Ralf Kress; Andreas Ziegler; John A Raeburn; Donata Campra; Robert Grützmann; Helga Rehder; Matthias Rothmund; Wolff Schmiegel; John P Neoptolemos; Detlef K Bartsch
BRCA2 germline mutations in familial pancreatic carcinoma.
Journal of the National Cancer Institute 2003;95(3):214-21.
2003: Clare J Roche; Mark L Hughes; Conall J Garvey; Fiona Campbell; Donagh A White; Lucie Jones; John P Neoptolemos
CT and pathologic assessment of prospective nodal staging in patients with ductal adenocarcinoma of the head of the pancreas.
AJR. American journal of roentgenology 2003;180(2):475-80.
2003: Robert Sutton; David N Criddle; Michael G T Raraty; Alexei V Tepikin; John P Neoptolemos; Ole H Petersen
Signal transduction, calcium and acute pancreatitis.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2003;3(6):497-505.
2003: Nicholas Alexakis; L Bosonnet; Saxon Connor; I Ellis; Robert Sutton; Fiona Campbell; M Hughes; Conall J Garvey; John P Neoptolemos
Double resection for patients with pancreatic cancer and a second primary renal cell cancer.
Digestive surgery 2003;20(5):428-32.
2003: Edoardo Rosso; Nicholas Alexakis; Paula Ghaneh; Martin Lombard; Howard Smart; Johnathan Evans; John P Neoptolemos
Pancreatic pseudocyst in chronic pancreatitis: endoscopic and surgical treatment.
Digestive surgery 2003;20(5):397-406.
2003: Saxon Connor; Paula Ghaneh; Michael G T Raraty; Robert Sutton; Edoardo Rosso; Conall J Garvey; Mark L Hughes; J C Evans; Peter C Rowlands; John P Neoptolemos
Minimally invasive retroperitoneal pancreatic necrosectomy.
Digestive surgery 2003;20(4):270-7.
2002: Nathan Howes; John P Neoptolemos
Risk of pancreatic ductal adenocarcinoma in chronic pancreatitis.
Gut 2002;51(6):765-6.
2002: Mark Brady; Madhav Bhatia; Stephen E Christmas; Mark T Boyd; John P Neoptolemos; John Slavin
Expression of the chemokines MCP-1/JE and cytokine-induced neutrophil chemoattractant in early acute pancreatitis.
Pancreas 2002;25(3):260-9.
2002: Hiram C Polk; Talmadge A Bowden; Layton F Rikkers; Charles M Balch; Claude H Organ; John A Murie; Walter J Pories; Markus W Buechler; John P Neoptolemos; Victor W Fazio; Seymour I Schwartz; John L Cameron; Keith A Kelly; Jay L Grosfeld; David W McFadden; Wiley W Souba; Basil A Pruitt; K Wayne Johnston; Robert B Rutherford; Maurice E Arregui; Carol E H Scott-Conner; Andrew L Warshaw; Michael G Sarr; Alfred Cuschieri; Bruce V MacFadyen; Ronald K Tompkins
Scientific data from clinical trials: investigators' responsibilities and rights.
Surgical laparoscopy, endoscopy & percutaneous techniques 2002;12(3):2 p preceding 145.
2002: Hiram C Polk; Talmadge A Bowden; Layton F Rikkers; Charles M Balch; Claude H Organ; John A Murie; Walter J Pories; Markus W Buechler; John P Neoptolemos; Victor W Fazio; Seymour I Schwartz; John L Cameron; Keith A Kelly; Jay L Grosfeld; David W McFadden; Wiley W Souba; Basil A Pruitt; K Wayne Johnson; Robert B Rutherford; Maurice E Arregui; Carol E H Scott-Conner; Andrew L Warshaw; Michael G Sarr; Alfred Cuschieri; Bruce V MacFadyen; Ronald K Tompkins
Consensus statement on scientific data from clinical trials and investigators' responsibilities and rights.
American journal of surgery 2002;183(6):605-6.
2002: Hiram C Polk; Talmadge A Bowden; Layton F Rikkers; Charles M Balch; John A Murie; Walter J Pories; Markus H Buechler; John P Neoptolemos; Victor W Fazio; Seymour I Schwartz; John L Cameron; Keith A Kelly
Scientific data from clinical trials: investigators' responsibilities and rights.
Journal of the American College of Surgeons 2002;194(6):851-2.
2002: Conor J Magee; Paula Ghaneh; John P Neoptolemos
Surgical and medical therapy for pancreatic carcinoma.
Best practice & research. Clinical gastroenterology 2002;16(3):435-55.
2002: Hiram C Polk; Talmadge A Bowden; Layton F Rikkers; Charles M Balch; John A Murie; Walter J Pories; Markus H Buechler; John P Neoptolemos; Victor W Fazio; Seymour I Schwartz; John L Cameron; Keith A Kelly; Jay L Grosfeld; David W McFadden; Wiley W Souba; Basil A Pruitt; K Wayne Johnston; Robert B Rutherford; Maurice E Arrequi; Carol E H Scott-Conner; Andrew L Warshaw; Michael G Sarr; Alfred Cuschieri; Bruce V MacFadyen; Ronald K Thompkins
Scientific data from clinical trials: investigators' responsibilities and rights.
Diseases of the colon and rectum 2002;45(6):725-6.
2002: Hiram C Polk; Talmadge A Bowden; Layton F Rikkers; Charles M Balch; Claude H Organ; John A Murie; Walter J Pories; Markus W Buechler; John P Neoptolemos; Victor W Fazio; Seymour I Schwartz; John I Cameron; Keith A Kelly; Jay L Grosfeld; David W McFadden; Wiley W Souba; Basil A Pruitt; K Wayne Johnston; Robert B Rutherford; Maurice E Arregui; Carol E H Scott-Conner; Andrew L Warshaw; Michael G Sarr; Alfred Cuschieri; Ronald K Tompkins; Bruce V MacFadyen
Scientific data from clinical trials: investigators' responsibilities and rights.
Annals of surgical oncology 2002;9(5):421-2.
2002: Hiram C Polk; Talmadge A Bowden; Layton F Rikkers; Charles M Balch; Claude H Organ; John A Murie; Walter J Pories; Markus W Buechler; John P Neoptolemos; Victor W Fazio; Seymour I Schwartz; John L Cameron; Jay L Grosfeld; David W McFadden; Wiley W Souby; Basil A Pruitt; K Wayne Johnston; Robert B Rutherford; Maurice E Arregui; Carol E H Scott-Conner; Andrew L Warshaw; Michael G Sarr; Alfred Cuschieri; Bruce V MacFadyen; Ronald K Tompkins
Scientific data from clinical trials: investigators' responsibilities and rights.
Archives of surgery (Chicago, Ill. : 1960) 2002;137(6):639-40.
2002: Hiram C Polk; Talmadge A Bowden; Layton F Rikkers; Charles M Balch; Claude H Organ; John A Murie; Walter J Pories; Markus W Buechler; John P Neoptolemos; Victor W Fazio; Seymour I Schwartz; John L Cameron; Keith A Kelly; Jay L Grosfeld; David W McFadden; Wiley W Souba; Basil A Pruitt; K Wayne Johnston; Robert B Rutherford; Maurice E Arregui; Carol E H Scott-Conner; Andrew L Warshaw; Michael G Sarr; Alfred Cuschieri; Bruce V MacFadyen; Ronald K Tompkins
Scientific data from clinical trials: investigators' responsibilities and rights.
World journal of surgery 2002;26(6):637-8.
2002: Hiram C Polk; Talmadge A Bowden; Layton F Rikkers; Charles M Balch; John A Murie; Walter J Pories; Markus H Buechler; John P Neoptolemos; Victor W Fazio; Seymour I Schwartz; John L Cameron; Keith A Kelley
Scientific data from clinical trials: investigators responsibilities and rights.
The Journal of trauma 2002;52(6):1017-8.
2002: Hiram C Polk; Talmadge A Bowden; Layton F Rikkers; Charles M Balch; Claude H Organ; John A Murie; Walter J Pories; Markus W Buechler; John P Neoptolemos; Victor W Fazio; Seymour I Schwartz; John L Cameron; Keith A Kelly; Jay L Grosfeld; David W McFadden; Wiley W Souba; Basil A Pruitt; K Wayne Johnston; Robert B Rutherford; Maurice E Arregui; Carol E H Scott-Conner; Andrew L Warshaw; Michael G Sarr; Alfred Cuschieri; Bruce V MacFadyen; Ronald K Tompkins
Scientific data from clinical trials: investigators' responsibilities and rights.
Journal of vascular surgery 2002;35(6):1303-4.
2002: Hiram C Polk; Talmadge A Bowden; Layton F Rikkers; Charles M Balch; Claude H Organ; John A Murie; Walter J Pories; Markus W Büchler; John P Neoptolemos; Victor W Fazio; Seymour I Schwartz; John L Cameron; Keith A Kelly; Jay L Grosfeld; David W McFadden; Wiley W Souba; Basil A Pruitt; K Wayne Johnston; Robert B Rutherford; Maurice E Arregui; Carol E H Scott-Conner; Andrew L Warshaw; Michael G Sarr; Alfred Cuschieri; Bruce V McFadyen; Ronald K Tompkins
Scientific data from clinical trials: investigators' responsibilities and rights.
The British journal of surgery 2002;89(6):678-9.
2002: Hiram C Polk; Talmadge A Bowden; Layton F Rikkers; Charles M Balch; Claude H Organ; John A Murie; Walter J Pories; Markus W Buechler; John P Neoptolemos; Victor W Fazio; Seymour I Schwartz; John L Cameron; Keith A Kelly; Jay L Grosfeld; David W McFadden; Wiley W Souba; Basil A Pruitt; K Wayne Johnston; Robert B Rutherford; Maurice E Arregui; Carol E H Scott-Conner; Andrew L Warshaw; Michael G Sarr; Alfred Cuschieri; Bruce V MacFadyen; Ronald K Tompkins
Scientific data from clinical trials: investigators' responsibilities and rights.
Surgical endoscopy 2002;16(6):1019-20.
2002: Hiram C Polk; Talmadge A Bowden; Layton F Rikkers; Charles M Balch; Claude H Organ; John A Murie; Walter J Pories; Markus W Buechler; John P Neoptolemos; Victor W Faxio; Seymour I Schwartz; John L Cameron; Keith A Kelly; Jay L Grosfeld; David W McFadden; Wiley W Souba; Basil A Pruitt; K Wayne Johnson; Robert B Rutherford; Maurice E Arregui; Carol E H Scott-Conner; Andrew L Warshaw; Michael G Sarr; Alfred Cuschieri; Bruce V MacFadyen; Ronald K Tompkins
Scientific data from clinical trials: investigators' responsibilities and rights.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2002;6(3):512-3.
2002: S Shokuhi; Madhav Bhatia; Stephen E Christmas; Robert Sutton; John P Neoptolemos; John Slavin
Levels of the chemokines growth-related oncogene alpha and epithelial neutrophil-activating protein 78 are raised in patients with severe acute pancreatitis.
The British journal of surgery 2002;89(5):566-72.
2002: Ulrich R Fölsch; John P Neoptolemos
Reason for performing endoscopic retrograde cholangiopancreatography (ERCP) and ES in a patient with severe gallstone pancreatitis even in the absence of main bile duct stones.
Pancreas 2002;24(4):412-4; author reply 414-7.
2002: Jane Threadgold; William Greenhalf; Ian Ellis; Nathan Howes; M M Lerch; P Simon; J Jansen; R Charnley; R Laugier; Luca Frulloni; A Oláh; M Delhaye; I Ihse; O B Schaffalitzky de Muckadell; A Andrén-Sandberg; CW Imrie; J Martinek; T M Gress; Roger Mountford; david whitcomb; John P Neoptolemos
The N34S mutation of SPINK1 (PSTI) is associated with a familial pattern of idiopathic chronic pancreatitis but does not cause the disease.
Gut 2002;50(5):675-81.
2002: Conor J Magee; Ali Shekouh; Paula Ghaneh; John P Neoptolemos
Update on pancreatic cancer.
Hospital medicine (London, England : 1998) 2002;63(4):200-6.
2002: Jens M Mayer; Michael G T Raraty; John Slavin; Esko Kemppainen; J Fitzpatrick; Antti Hietaranta; Pauli Puolakkainen; Hans G Beger; John P Neoptolemos
Serum amyloid A is a better early predictor of severity than C-reactive protein in acute pancreatitis.
The British journal of surgery 2002;89(2):163-71.
2002: Michael G T Raraty; Conor J Magee; Paula Ghaneh; John P Neoptolemos
New techniques and agents in the adjuvant therapy of pancreatic cancer.
Acta oncologica (Stockholm, Sweden) 2002;41(7-8):582-95.
2002: Waldemar Uhl; Andrew L Warshaw; Clement W Imrie; Claudio Bassi; Colin J McKay; Paul G Lankisch; Ross Carter; Eugene Di Magno; Peter A Banks; david whitcomb; Christos Dervenis; Charles D Ulrich; Kat Satake; Paula Ghaneh; Werner Hartwig; Jens Werner; Gerry McEntee; John P Neoptolemos; Markus W Büchler
IAP Guidelines for the Surgical Management of Acute Pancreatitis.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2002;2(6):565-73.
2002: Jens M Mayer; Michael G T Raraty; John Slavin; Esko Kemppainen; John Fitzpatrick; Antti Hietaranta; Pauli Puolakkainen; Hans G Beger; John P Neoptolemos
Severe acute pancreatitis is related to increased early urinary levels of the activation Peptide of pancreatic phospholipase A(2).
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2002;2(6):535-42.
2002: Ake Andrén-Sandberg; John P Neoptolemos
Resection for pancreatic cancer in the new millennium.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2002;2(5):431-9.
2002: Paula Ghaneh; Anthony Kawesha; James D Evans; John P Neoptolemos
Molecular prognostic markers in pancreatic cancer.
Journal of hepato-biliary-pancreatic surgery 2002;9(1):1-11.
2002: Christopher M Halloran; Paula Ghaneh; L Bosonnet; Mark Hartley; Robert Sutton; John P Neoptolemos
Complications of pancreatic cancer resection.
Digestive surgery 2002;19(2):138-46.
2002: Conor J Magee; Paula Ghaneh; Mark Hartley; Robert Sutton; John P Neoptolemos
The role of adjuvant therapy for pancreatic cancer.
Expert opinion on investigational drugs 2002;11(1):87-107.
2002: Madhav Bhatia; Mark Brady; Yun Kyung Kang; Eithne Costello; Darren J Newton; Stephen E Christmas; John P Neoptolemos; John Slavin
MCP-1 but not CINC synthesis is increased in rat pancreatic acini in response to cerulein hyperstimulation.
American journal of physiology. Gastrointestinal and liver physiology 2002;282(1):G77-85.
2001: J D Evans; A Stark; C D Johnson; F Daniel; J Carmichael; J Buckels; C W Imrie; P Brown; John P Neoptolemos
A phase II trial of marimastat in advanced pancreatic cancer.
British journal of cancer 2001;85(12):1865-70.
2001: John P Neoptolemos; Deborah D Stocken; Janet A Dunn; J Almond; Hans Beger; Paolo Pederzoli; Claudio Bassi; Christos Dervenis; Laureano Fernandez-Cruz; François Lacaine; J A C Buckels; Mark Deakin; F A Adab; R Sutton; C Imrie; I Ihse; Tibor Tihanyi; A Olah; S Pedrazzoli; David Spooner; David J Kerr; Helmut Friess; Markus W Büchler
Influence of resection margins on survival for patients with pancreatic cancer treated by adjuvant chemoradiation and/or chemotherapy in the ESPAC-1 randomized controlled trial.
Annals of surgery 2001;234(6):758-68.
2001: John P Neoptolemos; Janet A Dunn; Deborah D Stocken; J Almond; Karl-Heinrich Link; Hans Beger; Claudio Bassi; Massimo Falconi; Paolo Pederzoli; Christos Dervenis; Laureano Fernandez-Cruz; François Lacaine; A Pap; David Spooner; David J Kerr; Helmut Friess; Markus W Büchler
Adjuvant chemoradiotherapy and chemotherapy in resectable pancreatic cancer: a randomised controlled trial.
Lancet 2001;358(9293):1576-85.
2001: Paula Ghaneh; John Slavin; Robert Sutton; Mark Hartley; John P Neoptolemos
Adjuvant therapy in pancreatic cancer.
World journal of gastroenterology : WJG 2001;7(4):482-9.
2001: John Slavin; Paula Ghaneh; Robert Sutton; Mark Hartley; Peter C Rowlands; Conall J Garvey; M Hughes; John P Neoptolemos
Management of necrotizing pancreatitis.
World journal of gastroenterology : WJG 2001;7(4):476-81.
2001: Michelle J Humphreys; Paula Ghaneh; William Greenhalf; Fiona Campbell; T M Clayton; P Everett; B E Huber; C A Richards; M J Ford; John P Neoptolemos
Hepatic intra-arterial delivery of a retroviral vector expressing the cytosine deaminase gene, controlled by the CEA promoter and intraperitoneal treatment with 5-fluorocytosine suppresses growth of colorectal liver metastases.
Gene therapy 2001;8(16):1241-7.
2001: Conor J Magee; William Greenhalf; Nathan Howes; Paula Ghaneh; John P Neoptolemos
Molecular pathogenesis of pancreatic ductal adenocarcinoma and clinical implications.
Surgical oncology 2001;10(1-2):1-23.
2001: Esko Kemppainen; J Mayer; Pauli Puolakkainen; Michael G T Raraty; John Slavin; John P Neoptolemos
Plasma trypsinogen activation peptide in patients with acute pancreatitis.
The British journal of surgery 2001;88(5):679-80.
2001: Madhav Bhatia; John P Neoptolemos; John Slavin
Inflammatory mediators as therapeutic targets in acute pancreatitis.
Current opinion in investigational drugs (London, England : 2000) 2001;2(4):496-501.
2001: William M Steinberg; John P Neoptolemos; U R Fösch; Peter Layer
Controversies in clinical pancreatology. The management of severe gallstone pancreatitis.
Pancreas 2001;22(3):221-9.
2001: J Slavin; John P Neoptolemos
Antibiotic prophylaxis in severe acute pancreatitis--what are the facts?
Langenbeck's archives of surgery / Deutsche Gesellschaft für Chirurgie 2001;386(2):155-9.
2001: Paula Ghaneh; William Greenhalf; M Humphreys; D Wilson; L Zumstein; Nick Lemoine; John P Neoptolemos
Adenovirus-mediated transfer of p53 and p16(INK4a) results in pancreatic cancer regression in vitro and in vivo.
Gene therapy 2001;8(3):199-208.
2001: Nathan Howes; William Greenhalf; S Rutherford; M O'Donnell; Roger Mountford; Ian Ellis; david whitcomb; CW Imrie; Brendan Drumm; John P Neoptolemos
A new polymorphism for the RI22H mutation in hereditary pancreatitis.
Gut 2001;48(2):247-50.
2001: T Wong; Nathan Howes; Jane Threadgold; Howard Smart; Martin Lombard; Ian T Gilmore; Robert Sutton; William Greenhalf; Ian Ellis; John P Neoptolemos
Molecular diagnosis of early pancreatic ductal adenocarcinoma in high-risk patients.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2001;1(5):486-509.
2001: James D Evans; Philip A Cornford; Andrew Dodson; William Greenhalf; C S Foster; John P Neoptolemos
Detailed tissue expression of bcl-2, bax, bak and bcl-x in the normal human pancreas and in chronic pancreatitis, ampullary and pancreatic ductal adenocarcinomas.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2001;1(3):254-62.
2000: Philip A Cornford; Andrew Dodson; K F Parsons; Anthony Desmond; A Woolfenden; M V P Fordham; John P Neoptolemos; Y Ke; C S Foster
Heat shock protein expression independently predicts clinical outcome in prostate cancer.
Cancer research 2000;60(24):7099-105.
2000: Christopher M Halloran; Paula Ghaneh; John P Neoptolemos; Eithne Costello
Gene therapy for pancreatic cancer--current and prospective strategies.
Surgical oncology 2000;9(4):181-91.
2000: Madhav Bhatia; Mark Brady; J Zagorski; Stephen E Christmas; Fiona Campbell; John P Neoptolemos; John Slavin
Treatment with neutralising antibody against cytokine induced neutrophil chemoattractant (CINC) protects rats against acute pancreatitis associated lung injury.
Gut 2000;47(6):838-44.
2000: M Raraty; J Ward; Gül Erdemli; C Vaillant; John P Neoptolemos; R Sutton; Ole H Petersen
Calcium-dependent enzyme activation and vacuole formation in the apical granular region of pancreatic acinar cells.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(24):13126-31.
2000: Anthony Kawesha; Paula Ghaneh; A Andrén-Sandberg; D Ograed; R Skar; Sigmund Dawiskiba; James D Evans; Fiona Campbell; N Lemoine; John P Neoptolemos
K-ras oncogene subtype mutations are associated with survival but not expression of p53, p16(INK4A), p21(WAF-1), cyclin D1, erbB-2 and erbB-3 in resected pancreatic ductal adenocarcinoma.
International journal of cancer. Journal international du cancer 2000;89(6):469-74.
2000: John P Neoptolemos; E A Kemppainen; J M Mayer; J M Fitzpatrick; Michael G T Raraty; J Slavin; H G Beger; Antti Hietaranta; P A Puolakkainen
Early prediction of severity in acute pancreatitis by urinary trypsinogen activation peptide: a multicentre study.
Lancet 2000;355(9219):1955-60.
2000: Nathan Howes; William Greenhalf; John P Neoptolemos
Screening for early pancreatic ductal adenocarcinoma in hereditary pancreatitis.
The Medical clinics of North America 2000;84(3):719-38, xii.
2000: M Bhatia; M Brady; S Shokuhi; Stephen E Christmas; John P Neoptolemos; J Slavin
Inflammatory mediators in acute pancreatitis.
The Journal of pathology 2000;190(2):117-25.
2000: Paula Ghaneh; John Slavin; Robert Sutton; John P Neoptolemos
Adjuvant therapy for pancreatic cancer.
Swiss surgery = Schweizer Chirurgie = Chirurgie suisse = Chirurgia svizzera 2000;6(5):289-95.
2000: John Slavin; Paula Ghaneh; Robert Sutton; John P Neoptolemos
Pylorus-preserving Kausch-Whipple resection: the successor of the classical Kausch-Whipple in chronic pancreatitis.
Annali italiani di chirurgia 2000;71(1):57-64.
2000: J D Evans; Y Hamanaka; S P Olliff; John P Neoptolemos
Tuberculosis of the pancreas presenting as metastatic pancreatic carcinoma. A case report and review of the literature.
Digestive surgery 2000;17(2):183-7.
1999: Paula Ghaneh; Anthony Kawesha; Nathan Howes; L Jones; John P Neoptolemos
Adjuvant therapy for pancreatic cancer.
World journal of surgery 1999;23(9):937-45.
1999: Michelle J Humphreys; William Greenhalf; John P Neoptolemos; Paula Ghaneh
The potential for gene therapy in pancreatic cancer.
International journal of pancreatology : official journal of the International Association of Pancreatology 1999;26(1):5-21.
1999: Mark Brady; Stephen E Christmas; Robert Sutton; John P Neoptolemos; John Slavin
Cytokines and acute pancreatitis.
Baillière's best practice & research. Clinical gastroenterology 1999;13(2):265-89.
1999: Michael G T Raraty; O H Petersen; Robert Sutton; John P Neoptolemos
Intracellular free ionized calcium in the pathogenesis of acute pancreatitis.
Baillière's best practice & research. Clinical gastroenterology 1999;13(2):241-51.
1999: Paula Ghaneh; John P Neoptolemos
Exocrine pancreatic function following pancreatectomy.
Annals of the New York Academy of Sciences 1999;880():308-18.
1999: L Jones; Paula Ghaneh; M Humphreys; John P Neoptolemos
The matrix metalloproteinases and their inhibitors in the treatment of pancreatic cancer.
Annals of the New York Academy of Sciences 1999;880():288-307.
1999: John P Neoptolemos; Paula Ghaneh; A Andrén-Sandberg; S Bramhall; R Patankar; J H Kleibeuker; Colin D Johnson
Treatment of pancreatic exocrine insufficiency after pancreatic resection. Results of a randomized, double-blind, placebo-controlled, crossover study of high vs standard dose pancreatin.
International journal of pancreatology : official journal of the International Association of Pancreatology 1999;25(3):171-80.
1999: M M Lerch; I Ellis; david whitcomb; Volker Keim; P Simon; Nathan Howes; S Rutherford; W Domschke; C Imrie; John P Neoptolemos
Maternal inheritance pattern of hereditary pancreatitis in patients with pancreatic carcinoma.
Journal of the National Cancer Institute 1999;91(8):723-4.
1999: Robert Sutton; J P Slavin; Paula Ghaneh; John P Neoptolemos
Pancreatic disease: recent advances.
European journal of gastroenterology & hepatology 1999;11(1):33-6.
1999: L Jones; C Russell; F Mosca; U Boggi; Robert Sutton; John Slavin; Mark Hartley; John P Neoptolemos
Standard Kausch-Whipple pancreatoduodenectomy.
Digestive surgery 1999;16(4):297-304.
1999: John Slavin; Paula Ghaneh; L Jones; Robert Sutton; Mark Hartley; John P Neoptolemos
The future of surgery for pancreatic cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1999;10 Suppl 4():285-90.
1999: Paula Ghaneh; John P Neoptolemos
Pancreatic exocrine insufficiency following pancreatic resection.
Digestion 1999;60 Suppl 1():104-10.
1999: Philip A Cornford; J Evans; Andrew Dodson; K Parsons; A Woolfenden; John P Neoptolemos; C S Foster
Protein kinase C isoenzyme patterns characteristically modulated in early prostate cancer.
The American journal of pathology 1999;154(1):137-44.
1998: Michael G T Raraty; MD Finch; John P Neoptolemos
Acute cholangitis and pancreatitis secondary to common duct stones: management update.
World journal of surgery 1998;22(11):1155-61.
1998: John P Neoptolemos; Michael G T Raraty; M Finch; Robert Sutton
Acute pancreatitis: the substantial human and financial costs.
Gut 1998;42(6):886-91.
1998: MD Finch; John P Neoptolemos
Early ERCP in biliary pancreatitis?
HPB surgery : a world journal of hepatic, pancreatic and biliary surgery 1998;11(2):129-31.
1997: Michael G T Raraty; IM Pope; MD Finch; John P Neoptolemos
Choledocholithiasis and gallstone pancreatitis.
Baillière's clinical gastroenterology 1997;11(4):663-80.
1997: J D Evans; Sundaram Ramasamy; I A Donovan; Simon R Bramhall; John P Neoptolemos
Serum levels of insulin-like growth factors (IGF-I and IGF-II) and their binding protein (IGFBP-3) are not elevated in pancreatic cancer.
International journal of pancreatology : official journal of the International Association of Pancreatology 1997;22(2):95-100.
1997: John P Neoptolemos; R C Russell; Simon R Bramhall; Belinda A Theis
Low mortality following resection for pancreatic and periampullary tumours in 1026 patients: UK survey of specialist pancreatic units. UK Pancreatic Cancer Group.
The British journal of surgery 1997;84(10):1370-6.
1997: S Singh; P R Baker; R Poulsom; N A Wright; M C Sheppard; M J Langman; John P Neoptolemos
Expression of oestrogen receptor and oestrogen-inducible genes in pancreatic cancer.
The British journal of surgery 1997;84(8):1085-9.
1997: Y Hamanaka; J Evans; G Sagar; John P Neoptolemos
Complete pancreatic encasement of the proximal hepatic portal vein: a previously undescribed congenital anomaly.
The British journal of surgery 1997;84(6):785.
1997: J D Evans; P G Wilson; C Carver; Simon R Bramhall; J A Buckels; A David Mayer; P McMaster; John P Neoptolemos
Outcome of surgery for chronic pancreatitis.
The British journal of surgery 1997;84(5):624-9.
1997: John P Neoptolemos; P Baker; H Beger; Karl-Heinrich Link; Paolo Pederzoli; Claudio Bassi; Christos Dervenis; Helmut Friess; Markus W Büchler
Progress report. A randomized multicenter European study comparing adjuvant radiotherapy, 6-mo chemotherapy, and combination therapy vs no-adjuvant treatment in resectable pancreatic cancer (ESPAC-1).
International journal of pancreatology : official journal of the International Association of Pancreatology 1997;21(2):97-104.
1997: P G Wilson; OA Ogunbiyi; John P Neoptolemos
The timing of endoscopic sphincterotomy in gallstone acute pancreatitis.
European journal of gastroenterology & hepatology 1997;9(2):137-44.
1997: John P Neoptolemos; David J Kerr; H Beger; Karl-Heinrich Link; Paolo Pederzoli; Claudio Bassi; Christos Dervenis; Laureano Fernandez-Cruz; F Laçaine; Helmut Friess; Markus W Büchler
ESPAC-1 trial progress report: the European randomized adjuvant study comparing radiochemotherapy, 6 months chemotherapy and combination therapy versus observation in pancreatic cancer.
Digestion 1997;58(6):570-7.
1997: M D Finch; Nathan Howes; Ian Ellis; Roger Mountford; Robert Sutton; Michael G T Raraty; John P Neoptolemos
Hereditary pancreatitis and familial pancreatic cancer.
Digestion 1997;58(6):564-9.
1997: James D Evans; Paula Ghaneh; Anthony Kawesha; John P Neoptolemos
Role of matrix metalloproteinases and their inhibitors in pancreatic cancer.
Digestion 1997;58(6):520-8.
1997: P S Stonelake; C E Jones; John P Neoptolemos; P R Baker
Proteinase inhibitors reduce basement membrane degradation by human breast cancer cell lines.
British journal of cancer 1997;75(7):951-9.
1996: David J Kerr; A M Young; John P Neoptolemos; M Sherman; P Van-Geene; A Stanley; D Ferry; J W Dobbie; B Vincke; J Gilbert; D el Eini; N Dombros; G Fountzilas
Prolonged intraperitoneal infusion of 5-fluorouracil using a novel carrier solution.
British journal of cancer 1996;74(12):2032-5.
1996: J D Evans; P G Wilson; P C Barber; John P Neoptolemos
Duodenal gangliocytic paraganglioma presenting as an ampullary tumor.
International journal of pancreatology : official journal of the International Association of Pancreatology 1996;20(2):131-4.
1996: M C Crundwell; S Chughtai; M Knowles; L Takle; M Luscombe; John P Neoptolemos; Dion G Morton; S M Phillips
Allelic loss on chromosomes 8p, 22q and 18q (DCC) in human prostate cancer.
International journal of cancer. Journal international du cancer 1996;69(4):295-300.
1995: David J Kerr; J A Ledermann; C S McArdle; J Buckels; John P Neoptolemos; M Seymour; J Doughty; J Budden; I Taylor
Phase I clinical and pharmacokinetic study of leucovorin and infusional hepatic arterial fluorouracil.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1995;13(12):2968-72.
1995: C W Hendrickse; M R Keighley; John P Neoptolemos
Dietary omega-3 fats reduce proliferation and tumor yields at colorectal anastomosis in rats.
Gastroenterology 1995;109(2):431-9.
1995: I M Bain; A B Mostafa; L K Harding; John P Neoptolemos; M R Keighley
Bile acid absorption from ileoanal pouches using enema scintigraphy.
The British journal of surgery 1995;82(5):614-7.
1995: C W Hendrickse; S Radley; I A Donovan; M R Keighley; John P Neoptolemos
Activities of phospholipase A2 and diacylglycerol lipase are increased in human colorectal cancer.
The British journal of surgery 1995;82(4):475-8.
1995: Judit Pongracz; P Clark; John P Neoptolemos; J Michael Lord
Expression of protein kinase C isoenzymes in colorectal cancer tissue and their differential activation by different bile acids.
International journal of cancer. Journal international du cancer 1995;61(1):35-9.
1995: F T Curran; John P Neoptolemos
Acute biliary pancreatitis.
Annali italiani di chirurgia 1995;66(2):197-202.
1995: John P Neoptolemos; G D Oates; K M Newbold; A M Robson; C McConkey; J Powell
Cyclin/proliferation cell nuclear antigen immunohistochemistry does not improve the prognostic power of Dukes' or Jass' classifications for colorectal cancer.
The British journal of surgery 1995;82(2):184-7.
1995: Simon R Bramhall; W H Allum; A G Jones; A Allwood; Carole Cummins; John P Neoptolemos
Treatment and survival in 13,560 patients with pancreatic cancer, and incidence of the disease, in the West Midlands: an epidemiological study.
The British journal of surgery 1995;82(1):111-5.
1994: Yvonne Wallis; F Macdonald; M Hultén; J E Morton; C M McKeown; John P Neoptolemos; M R B Keighley; Dion G Morton
Genotype-phenotype correlation between position of constitutional APC gene mutation and CHRPE expression in familial adenomatous polyposis.
Human genetics 1994;94(5):543-8.
1994: C W Hendrickse; R W Kelly; S Radley; I A Donovan; M R Keighley; John P Neoptolemos
Lipid peroxidation and prostaglandins in colorectal cancer.
The British journal of surgery 1994;81(8):1219-23.
1994: A Moran; C Hendrickse; Alan F Jones; John P Neoptolemos
Enteric alpha-1-antitrypsin loss and comparison with Okokit II and Haemoccult for the detection of colorectal cancer.
Surgical oncology 1994;3(3):147-51.
1994: G M Barker; S Radley; A Davis; C H Imray; K D Setchell; N O'Connell; I A Donovan; M R Keighley; John P Neoptolemos
Unconjugated faecal bile acids in familial adenomatous polyposis analysed by gas-liquid chromatography and mass spectrometry.
The British journal of surgery 1994;81(5):739-42.
1994: G M Barker; S Radley; I Bain; A Davis; A M Lawson; M R Keighley; John P Neoptolemos
Biliary bile acid profiles in patients with familial adenomatous polyposis before and after colectomy.
The British journal of surgery 1994;81(3):441-4.
1994: W A Kmiot; E P Perry; I A Donovan; M J Lee; R F Wolverson; L K Harding; John P Neoptolemos
Cholesterolosis in patients with chronic acalculous biliary pain.
The British journal of surgery 1994;81(1):112-5.
1994: P S Stonelake; P G Baker; W M Gillespie; J A Dunn; D Spooner; J M Morrison; N J Bundred; G D Oates; M J Lee; John P Neoptolemos
Steroid receptors, pS2 and cathepsin D in early clinically node-negative breast cancer.
European journal of cancer (Oxford, England : 1990) 1994;30A(1):5-11.
1993: G M Barker; S Radley; A Davis; K D Setchell; N O'Connell; I A Donovan; M R Keighley; John P Neoptolemos
Analysis of faecal neutral sterols in patients with familial adenomatous polyposis by gas chromatography-mass spectrometry.
International journal of colorectal disease 1993;8(4):188-92.
1993: John P Neoptolemos; P Stonelake; S Radley
Endoscopic sphincterotomy for acute pancreatitis.
Hepato-gastroenterology 1993;40(6):550-5.
1993: C W Hendrickse; C E Jones; I A Donovan; John P Neoptolemos; P R Baker
Oestrogen and progesterone receptors in colorectal cancer and human colonic cancer cell lines.
The British journal of surgery 1993;80(5):636-40.
1993: John P Neoptolemos
Endoscopic sphincterotomy in acute gallstone pancreatitis.
The British journal of surgery 1993;80(5):547-9.
1993: Dion G Morton; F Macdonald; J Haydon; R Cullen; G Barker; M Hultén; John P Neoptolemos; M R B Keighley; C McKeown
Screening practice for familial adenomatous polyposis: the potential for regional registers.
The British journal of surgery 1993;80(2):255-8.
1993: A Moran; S Radley; John P Neoptolemos; Alan F Jones; P Asquith
Detection of colorectal cancer by faecal alpha 1-antitrypsin.
Annals of clinical biochemistry 1993;30 ( Pt 1)():28-33.
1993: John P Neoptolemos; N J London; David L. Carr-Locke
Assessment of main pancreatic duct integrity by endoscopic retrograde pancreatography in patients with acute pancreatitis.
The British journal of surgery 1993;80(1):94-9.
1992: G H Barsoum; H Thompson; John P Neoptolemos; M R Keighley
Dietary calcium does not reduce experimental colorectal carcinogenesis after small bowel resection despite reducing cellular proliferation.
Gut 1992;33(11):1515-20.
1992: C H Imray; S Radley; A Davis; G Barker; C W Hendrickse; I A Donovan; A M Lawson; P R Baker; John P Neoptolemos
Faecal unconjugated bile acids in patients with colorectal cancer or polyps.
Gut 1992;33(9):1239-45.
1992: C H Imray; K M Newbold; A Davis; M Lavelle-Jones; John P Neoptolemos
Induction of cholangiocarcinoma in the Golden Syrian hamster using methylazoxymethyl acetate.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 1992;18(4):373-8.
1992: Dion G Morton; F Macdonald; M B Cachon-Gonzales; P M Rindl; John P Neoptolemos; M R B Keighley; J D Delhanty; C M McKeown; M Kilpatrick; M A Hultén
The use of DNA from paraffin wax preserved tissue for predictive diagnosis in familial adenomatous polyposis.
Journal of medical genetics 1992;29(8):571-3.
1992: M Winslet; C Hall; N J London; John P Neoptolemos
Relation of diagnostic serum amylase levels to aetiology and severity of acute pancreatitis.
Gut 1992;33(7):982-6.
1992: Dion G Morton; J Gibson; F Macdonald; R Brown; J Haydon; R Cullen; M Rindl; M Hulten; John P Neoptolemos; M R B Keighley
Role of congenital hypertrophy of the retinal pigment epithelium in the predictive diagnosis of familial adenomatous polyposis.
The British journal of surgery 1992;79(7):689-93.
1992: G H Barsoum; C Hendrickse; Marc C Winslet; D Youngs; I A Donovan; John P Neoptolemos; M R Keighley
Reduction of mucosal crypt cell proliferation in patients with colorectal adenomatous polyps by dietary calcium supplementation.
The British journal of surgery 1992;79(6):581-3.
1992: F MacDonald; Dion G Morton; P M Rindl; J Haydon; R Cullen; J Gibson; John P Neoptolemos; M R B Keighley; C M McKeown; M Hultén
Predictive diagnosis of familial adenomatous polyposis with linked DNA markers: population based study.
BMJ (Clinical research ed.) 1992;304(6831):869-72.
1992: C H Imray; T Minoura; A Davis; S Radley; K M Newbold; M Lavelle-Jones; A M Lawson; P R Baker; John P Neoptolemos
Comparability of hamster with human faecal unconjugated bile acids in a model of colorectal cancer.
Anticancer research 1992;12(2):553-8.
1992: G H Barsoum; Marc C Winslet; D Youngs; John P Neoptolemos; M R Keighley
Influence of dietary calcium supplements on ileoanal pouch function and cytokinetics.
The British journal of surgery 1992;79(2):129-32.
1992: John P Neoptolemos; S Radley
Long-term results of choledochoduodenostomy.
HPB surgery : a world journal of hepatic, pancreatic and biliary surgery 1992;5(2):157-9.
1992: S Radley; A E Davis; C H Imray; G Barker; Dion G Morton; P R Baker; John P Neoptolemos
Biliary bile acid profiles in familial adenomatous polyposis.
The British journal of surgery 1992;79(1):89-90.
1991: John P Neoptolemos
Acute biliary pancreatitis.
The Italian journal of gastroenterology 1991;23(9):570-3.
1991: S Rowley; R Carpenter; K M Newbold; J Gearty; M R Keighley; I A Donovan; John P Neoptolemos
Use of the OM-11-906 monoclonal antibody for determining p62 c-myc expression by flow cytometry in relation to prognosis in colorectal cancer.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 1991;17(4):370-8.
1991: C Hall; N J Dorricott; I A Donovan; John P Neoptolemos
Colon perforation during colonoscopy: surgical versus conservative management.
The British journal of surgery 1991;78(5):542-4.
1991: Marc C Winslet; C Hall; C Hendrickse; N Lawson; John P Neoptolemos
Serum phospholipase A2 and free fatty acid levels in acute pancreatitis.
Biochemical Society transactions 1991;19(2):225S.
1991: C H Imray; A Davis; G Barker; S Radley; P Baker; John P Neoptolemos
Improved human faecal bile acid extraction.
Biochemical Society transactions 1991;19(2):201S.
1991: A E Davis; C H Imray; T Minoura; M Winslet; P R Baker; John P Neoptolemos
Gas liquid chromatography (GLC) analysis of hamster conjugated biliary bile acids.
Biochemical Society transactions 1991;19(2):171S.
1991: C H Imray; M Billingham; J Milles; A Wright; R Filer; J Bradwell; John P Neoptolemos
Changes in serum lipids after exercise and on exposure to altitude.
Biochemical Society transactions 1991;19(2):135S.
1991: Marc C Winslet; C Imray; John P Neoptolemos
Biliary acute pancreatitis.
Hepato-gastroenterology 1991;38(2):120-3.
1991: John P Neoptolemos; D Husband; C Imray; S Rowley; N Lawson
Arachidonic acid and docosahexaenoic acid are increased in human colorectal cancer.
Gut 1991;32(3):278-81.
1991: John P Neoptolemos; B Isgar
Relationship between cholesterolosis and pancreatitis.
HPB surgery : a world journal of hepatic, pancreatic and biliary surgery 1991;3(3):217-20.
1990: M Sakaguchi; C Imray; A Davis; S Rowley; C Jones; N Lawson; M R Keighley; P R Baker; John P Neoptolemos
Effects of dietary N-3 and saturated fats on growth rates of the human colonic cancer cell lines SW-620 and LS 174T in vivo in relation to tissue and plasma lipids.
Anticancer research 1990;10(6):1763-8.
1990: M Sakaguchi; S Rowley; N Kane; C Imray; A Davies; C Jones; M Newbold; M R Keighley; P Baker; John P Neoptolemos
Reduced tumour growth of the human colonic cancer cell lines COLO-320 and HT-29 in vivo by dietary n-3 lipids.
British journal of cancer 1990;62(5):742-7.
1990: C Hall; P N Hall; J P Wingate; John P Neoptolemos
Evaluation of herniography in the diagnosis of an occult abdominal wall hernia in symptomatic adults.
The British journal of surgery 1990;77(8):902-6.
1990: S Rowley; K M Newbold; J Gearty; M R Keighley; I A Donovan; John P Neoptolemos
Comparison of deoxyribonucleic acid ploidy and nuclear expressed p62 c-myc oncogene in the prognosis of colorectal cancer.
World journal of surgery 1990;14(4):545-50; discussion 551.
1990: John P Neoptolemos; B S Thomas
Erythrocyte membrane stearic acid: oleic acid ratios in colorectal cancer using tube capillary column gas liquid chromatography.
Annals of clinical biochemistry 1990;27 ( Pt 1)():38-43.
1990: John P Neoptolemos; C Hall; H J O'Connor; W R Murray; David L. Carr-Locke
Methyl-tert-butyl-ether for treating bile duct stones: the British experience.
The British journal of surgery 1990;77(1):32-5.
1989: John P Neoptolemos; S Rowley
Advantages of nonsurgical treatment of bile duct stones.
Hepato-gastroenterology 1989;36(5):313-6.
1989: C Hall; S Rowley; John P Neoptolemos
Anastomosis or stoma for low rectal cancer?
Postgraduate medical journal 1989;65(761):144-9.