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Anthony Nesburn

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M Cristina Kenney; Baruch D Kuppermann; Deepika Malik; Michael V Miceli; Anthony B Nesburn; Janelle M Pavlis; Claudio Ramirez; Kyaw Soe; Shari R Atilano; David S Boyer; Marilyn Chwa; Payam Falatoonzadeh; Tiffany Hsu; S Michal Jazwinski; Douglas C Wallace; Grace Woo; Nitin Udar
Mitochondrial DNA variants mediate energy production and expression levels for CFH, C3 and EFEMP1 genes: implications for age-related macular degeneration.
M Cristina Kenney; Nikan Khatibi; Jacqueline King; Jonathan Langberg; Masood Memarzadeh; Anthony B Nesburn; Andrew Nobe; Kent Small; Kyaw Soe; Shari R Atilano; David S Boyer; Garrick Chak; Marilyn Chwa; Dieter Hertzog; Elizabeth Yang; Feilin Zhu; Nitin Udar
Mitochondrial DNA haplogroups confer differences in risk for age-related macular degeneration: a case control study.
Aziz Alami Chentoufi; Gargi Dasgupta; Xavier Dervillez; Xianzhi Jiang; Khaled W Kabbara; Anthony B Nesburn; Chelsea Nguyen; Steven L Wechsler; Lbachir BenMohamed
The herpes simplex virus type 1 latency-associated transcript inhibits phenotypic and functional maturation of dendritic cells.

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All Publications

2013: M Cristina Kenney; Baruch D Kuppermann; Deepika Malik; Michael V Miceli; Anthony B Nesburn; Janelle M Pavlis; Claudio Ramirez; Kyaw Soe; Shari R Atilano; David S Boyer; Marilyn Chwa; Payam Falatoonzadeh; Tiffany Hsu; S Michal Jazwinski; Douglas C Wallace; Grace Woo; Nitin Udar
Mitochondrial DNA variants mediate energy production and expression levels for CFH, C3 and EFEMP1 genes: implications for age-related macular degeneration.
PloS one 2013;8(1):e54339.
2013: M Cristina Kenney; Nikan Khatibi; Jacqueline King; Jonathan Langberg; Masood Memarzadeh; Anthony B Nesburn; Andrew Nobe; Kent Small; Kyaw Soe; Shari R Atilano; David S Boyer; Garrick Chak; Marilyn Chwa; Dieter Hertzog; Elizabeth Yang; Feilin Zhu; Nitin Udar
Mitochondrial DNA haplogroups confer differences in risk for age-related macular degeneration: a case control study.
BMC medical genetics 2013;14():4.
2012: Aziz Alami Chentoufi; Gargi Dasgupta; Xavier Dervillez; Xianzhi Jiang; Khaled W Kabbara; Anthony B Nesburn; Chelsea Nguyen; Steven L Wechsler; Lbachir BenMohamed
The herpes simplex virus type 1 latency-associated transcript inhibits phenotypic and functional maturation of dendritic cells.
Viral immunology 2012;25(3):204-15.
2012: Aziz Alami Chentoufi; Elizabeth Kritzer; Anthony B Nesburn; David M Yu; Lbachir BenMohamed
Towards a rational design of an asymptomatic clinical herpes vaccine: the old, the new, and the unknown.
Clinical & developmental immunology 2012;2012():187585.
2011: Aziz Alami Chentoufi; Gargi Dasgupta; Chinhui Hsiang; Xianzhi Jiang; Elizabeth Kritzer; Chang Hyun Lim; Anthony B Nesburn; Nelson Osorio; Michael V Tran; Steven L Wechsler; David C Yu; Rasha E Afifi; Dale Carpenter; Lbachir BenMohamed
The herpes simplex virus 1 latency-associated transcript promotes functional exhaustion of virus-specific CD8+ T cells in latently infected trigeminal ganglia: a novel immune evasion mechanism.
Journal of virology 2011;85(17):9127-38.
2011: Gargi Dasgupta; Aziz Alami Chentoufi; Sylvaine You; Payam Falatoonzadeh; Lourie Ann A Urbano; Ayesha Akhtarmalik; Kimberly Nguyen; Lilit Ablabutyan; Anthony B Nesburn; Lbachir BenMohamed
Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses.
Investigative ophthalmology & visual science 2011;52(6):3321-33.
2010: M Cristina Kenney; Shari R Atilano; David Boyer; Marilyn Chwa; Garrick Chak; Sahmon Chinichian; Pinar E Coskun; Douglas C Wallace; Anthony B Nesburn; Nitin S Udar
Characterization of retinal and blood mitochondrial DNA from age-related macular degeneration patients.
Investigative ophthalmology & visual science 2010;51(8):4289-97.
2010: Aziz Alami Chentoufi; Gargi Dasgupta; Neil D Christensen; Jiafen Hu; Zareen S Choudhury; Arfan Azeem; James V Jester; Anthony B Nesburn; Steven L Wechsler; Lbachir BenMohamed
A novel HLA (HLA-A*0201) transgenic rabbit model for preclinical evaluation of human CD8+ T cell epitope-based vaccines against ocular herpes.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(5):2561-71.
2010: Aziz Alami Chentoufi; Gargi Dasgupta; Anthony B Nesburn; Ilham Bettahi; Nicholas R Binder; Zareen S Choudhury; Winston Chamberlain; Steven L Wechsler; Lbachir BenMohamed
Nasolacrimal duct closure modulates ocular mucosal and systemic CD4(+) T-cell responses induced following topical ocular or intranasal immunization.
Clinical and vaccine immunology : CVI 2010;17(3):342-53.
2010: Olivier Renaudet; Gargi Dasgupta; Ilham Bettahi; Alda Shi; Anthony B Nesburn; Pascal DUMY; Lbachir BenMohamed
Linear and branched glyco-lipopeptide vaccines follow distinct cross-presentation pathways and generate different magnitudes of antitumor immunity.
PloS one 2010;5(6):e11216.
2010: Gargi Dasgupta; Anthony B Nesburn; Steven L Wechsler; Lbachir BenMohamed
Developing an asymptomatic mucosal herpes vaccine: the present and the future.
Future microbiology 2010;5(1):1-4.
2009: Aziz Alami Chentoufi; Anthony B Nesburn; Lbachir BenMohamed
Recent advances in multivalent self adjuvanting glycolipopeptide vaccine strategies against breast cancer.
Archivum immunologiae et therapiae experimentalis 2009;57(6):409-23.
2009: Nitin Udar; Shari R Atilano; Kent W Small; Anthony B Nesburn; M Cristina Kenney
SOD1 haplotypes in familial keratoconus.
Cornea 2009;28(8):902-7.
2009: Gargi Dasgupta; Aziz Alami Chentoufi; Anthony B Nesburn; Steven L Wechsler; Lbachir BenMohamed
New concepts in herpes simplex virus vaccine development: notes from the battlefield.
Expert review of vaccines 2009;8(8):1023-35.
2009: Nitin Udar; Shari R Atilano; Masood Memarzadeh; David S Boyer; Marilyn Chwa; Stephanie Lu; Barak Maguen; Jonathan Langberg; Pinar E Coskun; Douglas C Wallace; Anthony B Nesburn; Nikan Khatibi; Dieter Hertzog; Khoi Le; Daniel Hwang; M Cristina Kenney
Mitochondrial DNA haplogroups associated with age-related macular degeneration.
Investigative ophthalmology & visual science 2009;50(6):2966-74.
2009: Xiuli Zhang; Aziz Alami Chentoufi; G Dasgupta; Anthony B Nesburn; M Wu; Xiaoming Zhu; D Carpenter; Steven L Wechsler; S You; Lbachir BenMohamed
A genital tract peptide epitope vaccine targeting TLR-2 efficiently induces local and systemic CD8+ T cells and protects against herpes simplex virus type 2 challenge.
Mucosal immunology 2009;2(2):129-43.
2008: Aziz Alami Chentoufi; Xiuli Zhang; Kasper Lamberth; Gargi Dasgupta; Ilham Bettahi; Alex Nguyen; Michelle Wu; Xiaoming Zhu; Amir Mohebbi; Soren Buus; Steven L Wechsler; Anthony B Nesburn; Lbachir BenMohamed
HLA-A*0201-restricted CD8+ cytotoxic T lymphocyte epitopes identified from herpes simplex virus glycoprotein D.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(1):426-37.
2007: Ilham Bettahi; Anthony B Nesburn; Susan Yoon; Xiuli Zhang; Amir Mohebbi; Valerie Sue; Aaron Vanderberg; Steven L Wechsler; Lbachir BenMohamed
Protective immunity against ocular herpes infection and disease induced by highly immunogenic self-adjuvanting glycoprotein D lipopeptide vaccines.
Investigative ophthalmology & visual science 2007;48(10):4643-53.
2007: Anthony B Nesburn; Ilham Bettahi; Gargi Dasgupta; Alami Aziz Chentoufi; Xiuli Zhang; Sylvaine You; Naoyuki Morishige; Andrew J Wahlert; Donald J Brown; James V Jester; Steven L Wechsler; Lbachir BenMohamed
Functional Foxp3+ CD4+ CD25(Bright+) "natural" regulatory T cells are abundant in rabbit conjunctiva and suppress virus-specific CD4+ and CD8+ effector T cells during ocular herpes infection.
Journal of virology 2007;81(14):7647-61.
2007: Raja Narayanan; Virit Butani; David S Boyer; Shari R Atilano; Gilberto P Resende; David S Kim; Subhabrata Chakrabarti; Baruch D Kuppermann; Nikan Khatibi; Marilyn Chwa; Anthony B Nesburn; M Cristina Kenney
Complement factor H polymorphism in age-related macular degeneration.
Ophthalmology 2007;114(7):1327-31.
2007: Kevin Mott; Yanira Osorio; Ezra Maguen; Anthony B Nesburn; Alec E Wittek; Steve Cai; Subhendra Chattopadhyay; Homayon Ghiasi
Role of anti-glycoproteins D (anti-gD) and K (anti-gK) IgGs in pathology of herpes stromal keratitis in humans.
Investigative ophthalmology & visual science 2007;48(5):2185-93.
2006: Anthony B Nesburn; Ilham Bettahi; Xiuli Zhang; Xiaoming Zhu; Winston Chamberlain; Rasha E Afifi; Steven L Wechsler; Lbachir BenMohamed
Topical/mucosal delivery of sub-unit vaccines that stimulate the ocular mucosal immune system.
The ocular surface 2006;4(4):178-87.
2006: Nitin Udar; Shari R Atilano; Donald J Brown; Bret Holguin; Kent W Small; Anthony B Nesburn; M Cristina Kenney
SOD1: a candidate gene for keratoconus.
Investigative ophthalmology & visual science 2006;47(8):3345-51.
2005: Xiuli Zhang; Annie Issagholian; Eric A Berg; Jordan B Fishman; Anthony B Nesburn; Lbachir BenMohamed
Th-cytotoxic T-lymphocyte chimeric epitopes extended by Nepsilon-palmitoyl lysines induce herpes simplex virus type 1-specific effector CD8+ Tc1 responses and protect against ocular infection.
Journal of virology 2005;79(24):15289-301.
2005: Anthony B Nesburn; Thomas V Ramos; Xiaoming Zhu; Hanieh Asgarzadeh; Vu Nguyen; Lbachir BenMohamed
Local and systemic B cell and Th1 responses induced following ocular mucosal delivery of multiple epitopes of herpes simplex virus type 1 glycoprotein D together with cytosine-phosphate-guanine adjuvant.
Vaccine 2005;23(7):873-83.
2004: Weiping Peng; Ling Jin; Gail Henderson; Guey Chuen Perng; David J Brick; Anthony B Nesburn; Steven L Wechsler; Clinton Jones
Mapping herpes simplex virus type 1 latency-associated transcript sequences that protect from apoptosis mediated by a plasmid expressing caspase-8.
Journal of neurovirology 2004;10(4):260-5.
2004: Ling Jin; Guey Chuen Perng; David J Brick; Julie Naito; Anthony B Nesburn; Clinton Jones; Steven L Wechsler
Methods for detecting the HSV-1 LAT anti-apoptosis activity in virus infected tissue culture cells.
Journal of virological methods 2004;118(1):9-13.
2004: Gail Henderson; Guey Chuen Perng; Anthony B Nesburn; Steven L Wechsler; Clinton Jones
The latency-related gene encoded by bovine herpesvirus 1 can suppress caspase 3 and caspase 9 cleavage during productive infection.
Journal of neurovirology 2004;10(1):64-70.
2004: Nitin Udar; M Cristina Kenney; Meenal Chalukya; Tara Anderson; Liezel Morales; Donald Brown; Anthony B Nesburn; Kent W Small
Keratoconus--no association with the transforming growth factor beta-induced gene in a cohort of American patients.
Cornea 2004;23(1):13-7.
2003: Weiping Peng; Gail Henderson; Guey Chuen Perng; Anthony B Nesburn; Steven L Wechsler; Clinton Jones
The gene that encodes the herpes simplex virus type 1 latency-associated transcript influences the accumulation of transcripts (Bcl-x(L) and Bcl-x(S)) that encode apoptotic regulatory proteins.
Journal of virology 2003;77(19):10714-8.
2003: Lbachir BenMohamed; Georges Bertrand; Cory D McNamara; Hélène Gras-Masse; Juergen Hammer; Steven L Wechsler; Anthony B Nesburn
Identification of novel immunodominant CD4+ Th1-type T-cell peptide epitopes from herpes simplex virus glycoprotein D that confer protective immunity.
Journal of virology 2003;77(17):9463-73.
2003: John M Ong; Nadia C Zorapapel; Annette M Aoki; Donald J Brown; Anthony B Nesburn; Kathryn A Rich; Cristina M Kenney
Impaired electroretinogram (ERG) response in apolipoprotein E-deficient mice.
Current eye research 2003;27(1):15-24.
2003: Ling Jin; Weiping Peng; Guey Chuen Perng; David J Brick; Anthony B Nesburn; Clinton Jones; Steven L Wechsler
Identification of herpes simplex virus type 1 latency-associated transcript sequences that both inhibit apoptosis and enhance the spontaneous reactivation phenotype.
Journal of virology 2003;77(11):6556-61.
2003: John M Ong; Annette M Aoki; Gail Seigel; Ingrid Sacerio; Raquel Castellon; Anthony B Nesburn; M Cristina Kenney
Oxysterol-induced toxicity in R28 and ARPE-19 cells.
Neurochemical research 2003;28(6):883-91.
2002: Silke Schmidt; Caroline Klaver; Ann M Saunders; Eric A Postel; Monica A De La Paz; Anita Agarwal; Kent W Small; Nitin Udar; John Ong; Meenal Chalukya; Anthony B Nesburn; Cristina Kenney; Ruth Domurath; Molly Hogan; Tammy Mah; Yvette P Conley; Robert Ferrell; Daniel Weeks; Paulus T V M de Jong; Cornelia van Duijn; Jonathan L Haines; Margaret Pericak-Vance; Michael B Gorin
A pooled case-control study of the apolipoprotein E (APOE) gene in age-related maculopathy.
Ophthalmic genetics 2002;23(4):209-23.
2002: Gail Henderson; Weiping Peng; Ling Jin; Guey Chuen Perng; Anthony B Nesburn; Steven L Wechsler; Clinton Jones
Regulation of caspase 8- and caspase 9-induced apoptosis by the herpes simplex virus type 1 latency-associated transcript.
Journal of neurovirology 2002;8 Suppl 2():103-11.
2002: Guey Chuen Perng; Kevin Mott; Nelson Osorio; Ada Yukht; Susan Salina; Quynh-Hoa Nguyen; Anthony B Nesburn; Steven L Wechsler
Herpes simplex virus type 1 mutants containing the KOS strain ICP34.5 gene in place of the McKrae ICP34.5 gene have McKrae-like spontaneous reactivation but non-McKrae-like virulence.
The Journal of general virology 2002;83(Pt 12):2933-42.
2002: Yanira Osorio; Steven L Wechsler; Anthony B Nesburn; Homayon Ghiasi
Reduced severity of HSV-1-induced corneal scarring in IL-12-deficient mice.
Virus research 2002;90(1-2):317-26.
2002: Homayon Ghiasi; Yanira Osorio; Anthony B Nesburn; Steven L Wechsler
Enhanced clearance of herpes simplex virus type 1 and reduced herpetic eye disease in STAT6 knockout mice is associated with increased IL-2.
Virology 2002;302(2):286-93.
2002: Homayon Ghiasi; Yanira Osorio; Yahya Hedvat; Guey Chuen Perng; Anthony B Nesburn; Steven L Wechsler
Infection of BALB/c mice with a herpes simplex virus type 1 recombinant virus expressing IFN-gamma driven by the LAT promoter.
Virology 2002;302(1):144-54.
2002: Homayon Ghiasi; Yanira Osorio; Guey Chuen Perng; Anthony B Nesburn; Steven L Wechsler
Overexpression of interleukin-2 by a recombinant herpes simplex virus type 1 attenuates pathogenicity and enhances antiviral immunity.
Journal of virology 2002;76(18):9069-78.
2002: Guey Chuen Perng; Barak Maguen; Ling Jin; Kevin Mott; John Kurylo; Lbachir BenMohamed; Ada Yukht; Nelson Osorio; Anthony B Nesburn; Gail Henderson; Melissa Inman; Clinton Jones; Steven L Wechsler
A novel herpes simplex virus type 1 transcript (AL-RNA) antisense to the 5' end of the latency-associated transcript produces a protein in infected rabbits.
Journal of virology 2002;76(16):8003-10.
2002: hamdi Khalil hamdi; Jacob Reznik; Raquel Castellon; Shari R Atilano; John M Ong; Nitin Udar; Jeffrey H Tavis; Annette M Aoki; Anthony B Nesburn; David S Boyer; Kent W Small; Donald J Brown; M Cristina Kenney
Alu DNA polymorphism in ACE gene is protective for age-related macular degeneration.
Biochemical and biophysical research communications 2002;295(3):668-72.
2002: Lbachir BenMohamed; Steven L Wechsler; Anthony B Nesburn
Lipopeptide vaccines--yesterday, today, and tomorrow.
The Lancet infectious diseases 2002;2(7):425-31.
2002: Ken Samoto; Moneeb Ehtesham; Guey Chuen Perng; Kazuhiro Hashizume; Steven L Wechsler; Anthony B Nesburn; Keith L Black; John S Yu
A herpes simplex virus type 1 mutant with gamma 34.5 and LAT deletions effectively oncolyses human U87 glioblastomas in nude mice.
Neurosurgery 2002;50(3):599-605; discussion 605-6.
2002: Guey Chuen Perng; Barak Maguen; Ling Jin; Kevin Mott; Nelson Osorio; Susan M Slanina; Ada Yukht; Homayon Ghiasi; Anthony B Nesburn; Melissa Inman; Gail Henderson; Clinton Jones; Steven L Wechsler
A gene capable of blocking apoptosis can substitute for the herpes simplex virus type 1 latency-associated transcript gene and restore wild-type reactivation levels.
Journal of virology 2002;76(3):1224-35.
2002: Alexander V Ljubimov; Shari R Atilano; Margaret H Garner; Ezra Maguen; Anthony B Nesburn; M Cristina Kenney
Extracellular matrix and Na+,K+-ATPase in human corneas following cataract surgery: comparison with bullous keratopathy and Fuchs' dystrophy corneas.
Cornea 2002;21(1):74-80.
2001: Homayon Ghiasi; Yanira Osorio; Guey Chuen Perng; Anthony B Nesburn; Steven L Wechsler
Recombinant herpes simplex virus type 1 expressing murine interleukin-4 is less virulent than wild-type virus in mice.
Journal of virology 2001;75(19):9029-36.
2001: Guey Chuen Perng; D Esmaili; Susan M Slanina; Ada Yukht; Homayon Ghiasi; Nelson Osorio; Kevin Mott; Barak Maguen; Ling Jin; Anthony B Nesburn; Steven L Wechsler
Three herpes simplex virus type 1 latency-associated transcript mutants with distinct and asymmetric effects on virulence in mice compared with rabbits.
Journal of virology 2001;75(19):9018-28.
2001: Guey Chuen Perng; Susan M Slanina; Homayon Ghiasi; Anthony B Nesburn; Steven L Wechsler
The effect of latency-associated transcript on the herpes simplex virus type 1 latency-reactivation phenotype is mouse strain-dependent.
The Journal of general virology 2001;82(Pt 5):1117-22.
2001: Ken Samoto; Guey Chuen Perng; Moneeb Ehtesham; Yunhui Liu; Steven L Wechsler; Anthony B Nesburn; Keith L Black; John S Yu
A herpes simplex virus type 1 mutant deleted for gamma34.5 and LAT kills glioma cells in vitro and is inhibited for in vivo reactivation.
Cancer gene therapy 2001;8(4):269-77.
2001: Melissa Inman; Guey Chuen Perng; Gail Henderson; Homayon Ghiasi; Anthony B Nesburn; Steven L Wechsler; Clinton Jones
Region of herpes simplex virus type 1 latency-associated transcript sufficient for wild-type spontaneous reactivation promotes cell survival in tissue culture.
Journal of virology 2001;75(8):3636-46.
2001: Marguerite B McDonald; JD Carr; J M Frantz; A M Kozarsky; Ezra Maguen; Anthony B Nesburn; Yaron S Rabinowitz; James Salz; R Doyle Stulting; Keith P Thompson; George O Waring
Laser in situ keratomileusis for myopia up to -11 diopters with up to -5 diopters of astigmatism with the summit autonomous LADARVision excimer laser system.
Ophthalmology 2001;108(2):309-16.
2000: Homayon Ghiasi; Florence M Hofman; K Wallner; Steve Cai; Guey Chuen Perng; Anthony B Nesburn; Steven L Wechsler
Corneal macrophage infiltrates following ocular herpes simplex virus type 1 challenge vary in BALB/c mice vaccinated with different vaccines.
Vaccine 2000;19(9-10):1266-73.
2000: Homayon Ghiasi; Guey Chuen Perng; Anthony B Nesburn; Steven L Wechsler
Antibody-dependent enhancement of HSV-1 infection by anti-gK sera.
Virus research 2000;68(2):137-44.
2000: Homayon Ghiasi; S Cai; Guey Chuen Perng; Anthony B Nesburn; Steven L Wechsler
Both CD4+ and CD8+ T cells are involved in protection against HSV-1 induced corneal scarring.
The British journal of ophthalmology 2000;84(4):408-12.
2000: Guey Chuen Perng; Clinton Jones; JR Ciacci-Zanella; M Stone; Gail Henderson; Ada Yukht; Susan M Slanina; Florence M Hofman; Homayon Ghiasi; Anthony B Nesburn; Steven L Wechsler
Virus-induced neuronal apoptosis blocked by the herpes simplex virus latency-associated transcript.
Science (New York, N.Y.) 2000;287(5457):1500-3.
2000: Guey Chuen Perng; Susan M Slanina; Ada Yukht; Homayon Ghiasi; Anthony B Nesburn; Steven L Wechsler
The latency-associated transcript gene enhances establishment of herpes simplex virus type 1 latency in rabbits.
Journal of virology 2000;74(4):1885-91.
2000: Homayon Ghiasi; S Cai; Guey Chuen Perng; Anthony B Nesburn; Steven L Wechsler
The role of natural killer cells in protection of mice against death and corneal scarring following ocular HSV-1 infection.
Antiviral research 2000;45(1):33-45.
1999: Homayon Ghiasi; Steve Cai; Guey Chuen Perng; Anthony B Nesburn; Steven L Wechsler
Perforin pathway is essential for protection of mice against lethal ocular HSV-1 challenge but not corneal scarring.
Virus research 1999;65(2):97-101.
1999: Homayon Ghiasi; Guey Chuen Perng; Anthony B Nesburn; Steven L Wechsler
Either a CD4(+)or CD8(+)T cell function is sufficient for clearance of infectious virus from trigeminal ganglia and establishment of herpes simplex virus type 1 latency in mice.
Microbial pathogenesis 1999;27(6):387-94.
1999: Guey Chuen Perng; Susan M Slanina; Ada Yukht; Homayon Ghiasi; Anthony B Nesburn; Steven L Wechsler
Herpes simplex virus type 1 serum neutralizing antibody titers increase during latency in rabbits latently infected with latency-associated transcript (LAT)-positive but not LAT-negative viruses.
Journal of virology 1999;73(11):9669-72.
1999: Marguerite B McDonald; M R Deitz; J M Frantz; M C Kraff; R R Krueger; James Salz; C R Kraff; Ezra Maguen; C S Matta; Anthony B Nesburn; L W Piebenga
Photorefractive keratectomy for low-to-moderate myopia and astigmatism with a small-beam, tracker-directed excimer laser.
Ophthalmology 1999;106(8):1481-8; discussion 1488-9.
1999: Homayon Ghiasi; Guey Chuen Perng; Florence M Hofman; Steve Cai; Anthony B Nesburn; Steven L Wechsler; G C Pemg
Specific and nonspecific immune stimulation of MHC-II-deficient mice results in chronic HSV-1 infection of the trigeminal ganglia following ocular challenge.
Virology 1999;258(2):208-16.
1999: Homayon Ghiasi; Florence M Hofman; Steve Cai; Guey Chuen Perng; Anthony B Nesburn; Steven L Wechsler
Vaccination with different HSV-1 glycoproteins induces different patterns of ocular cytokine responses following HSV-1 challenge of vaccinated mice.
Vaccine 1999;17(20-21):2576-82.
1999: Homayon Ghiasi; Steve Cai; Susan M Slanina; Guey Chuen Perng; Anthony B Nesburn; Steven L Wechsler
The role of interleukin (IL)-2 and IL-4 in herpes simplex virus type 1 ocular replication and eye disease.
The Journal of infectious diseases 1999;179(5):1086-93.
1999: Guey Chuen Perng; Susan M Slanina; Ada Yukht; BS Drolet; W Keleher; Homayon Ghiasi; Anthony B Nesburn; Steven L Wechsler
A herpes simplex virus type 1 latency-associated transcript mutant with increased virulence and reduced spontaneous reactivation.
Journal of virology 1999;73(2):920-9.
1999: BS Drolet; Guey Chuen Perng; R J Villosis; Susan M Slanina; Anthony B Nesburn; Steven L Wechsler
Expression of the first 811 nucleotides of the herpes simplex virus type 1 latency-associated transcript (LAT) partially restores wild-type spontaneous reactivation to a LAT-null mutant.
Virology 1999;253(1):96-106.
1999: Jeannette M Loutsch; Guey Chuen Perng; James M Hill; Xiaodong Zheng; Mary E Marquart; TM Block; Homayon Ghiasi; Anthony B Nesburn; Steven L Wechsler
Identical 371-base-pair deletion mutations in the LAT genes of herpes simplex virus type 1 McKrae and 17syn+ result in different in vivo reactivation phenotypes.
Journal of virology 1999;73(1):767-71.
1998: Anthony B Nesburn; RL Burke; Homayon Ghiasi; Susan M Slanina; Steven L Wechsler
Therapeutic periocular vaccination with a subunit vaccine induces higher levels of herpes simplex virus-specific tear secretory immunoglobulin A than systemic vaccination and provides protection against recurrent spontaneous ocular shedding of virus in latently infected rabbits.
Virology 1998;252(1):200-9.
1998: Homayon Ghiasi; Steven L Wechsler; Steve Cai; Anthony B Nesburn; Florence M Hofman
The role of neutralizing antibody and T-helper subtypes in protection and pathogenesis of vaccinated mice following ocular HSV-1 challenge.
Immunology 1998;95(3):352-9.
1998: Anthony B Nesburn; Susan M Slanina; RL Burke; Homayon Ghiasi; S Bahri; Steven L Wechsler
Local periocular vaccination protects against eye disease more effectively than systemic vaccination following primary ocular herpes simplex virus infection in rabbits.
Journal of virology 1998;72(10):7715-21.
1998: Alexander V Ljubimov; SA Alba; Robert E Burgeson; Y Ninomiya; Y Sado; Tung-Tien Sun; Anthony B Nesburn; M Cristina Kenney; Ezra Maguen
Extracellular matrix changes in human corneas after radial keratotomy.
Experimental eye research 1998;67(3):265-72.
1998: Anthony B Nesburn; RL Burke; Homayon Ghiasi; Susan M Slanina; Steven L Wechsler
A therapeutic vaccine that reduces recurrent herpes simplex virus type 1 corneal disease.
Investigative ophthalmology & visual science 1998;39(7):1163-70.
1998: BS Drolet; Guey Chuen Perng; J Cohen; Susan M Slanina; Ada Yukht; Anthony B Nesburn; Steven L Wechsler
The region of the herpes simplex virus type 1 LAT gene involved in spontaneous reactivation does not encode a functional protein.
Virology 1998;242(1):221-32.
1998: Homayon Ghiasi; Anthony B Nesburn; S Cai; Steven L Wechsler
The US5 open reading frame of herpes simplex virus type 1 does encode a glycoprotein (gJ).
Intervirology 1998;41(2-3):91-7.
1997: Ezra Maguen; SA Alba; Robert E Burgeson; RJ Butkowski; Alfred F Michael; M Cristina Kenney; Anthony B Nesburn; Alexander V Ljubimov
Alterations of corneal extracellular matrix after multiple refractive procedures: a clinical and immunohistochemical study.
Cornea 1997;16(6):675-82.
1997: Homayon Ghiasi; Steve Cai; Anthony B Nesburn; Steven L Wechsler
MHC-II but not MHC-I responses are required for vaccine-induced protection against ocular challenge with HSV-1.
Current eye research 1997;16(11):1152-8.
1997: Homayon Ghiasi; D C Roopenian; Susan M Slanina; Steve Cai; Anthony B Nesburn; Steven L Wechsler
The importance of MHC-I and MHC-II responses in vaccine efficacy against lethal herpes simplex virus type 1 challenge.
Immunology 1997;91(3):430-5.
1997: Homayon Ghiasi; Steve Cai; Susan M Slanina; Anthony B Nesburn; Steven L Wechsler
Nonneutralizing antibody against the glycoprotein K of herpes simplex virus type-1 exacerbates herpes simplex virus type-1-induced corneal scarring in various virus-mouse strain combinations.
Investigative ophthalmology & visual science 1997;38(6):1213-21.
1997: M Cristina Kenney; Anthony B Nesburn; Robert E Burgeson; RJ Butkowski; Alexander V Ljubimov
Abnormalities of the extracellular matrix in keratoconus corneas.
Cornea 1997;16(3):345-51.
1997: Ezra Maguen; Anthony B Nesburn; James Salz
Bilateral photorefractive keratectomy with intentional unilateral undercorrection in an aircraft pilot.
Journal of cataract and refractive surgery 1997;23(2):294-6.
1996: Alexander V Ljubimov; Robert E Burgeson; RJ Butkowski; John R Couchman; L Zardi; Y Ninomiya; Y Sado; Z S Huang; Anthony B Nesburn; M Cristina Kenney
Basement membrane abnormalities in human eyes with diabetic retinopathy.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1996;44(12):1469-79.
1996: Homayon Ghiasi; Guey Chuen Perng; S Cai; Anthony B Nesburn; Steven L Wechsler
The UL3 open reading frame of herpes simplex virus type 1 codes for a phosphoprotein.
Virus research 1996;44(2):137-42.
1996: Alexander V Ljubimov; Robert E Burgeson; RJ Butkowski; John R Couchman; R R Wu; Y Ninomiya; Y Sado; Ezra Maguen; Anthony B Nesburn; M Cristina Kenney
Extracellular matrix alterations in human corneas with bullous keratopathy.
Investigative ophthalmology & visual science 1996;37(6):997-1007.
1996: Guey Chuen Perng; Homayon Ghiasi; Susan M Slanina; Anthony B Nesburn; Steven L Wechsler
High-dose ocular infection with a herpes simplex virus type 1 ICP34.5 deletion mutant produces no corneal disease or neurovirulence yet results in wild-type levels of spontaneous reactivation.
Journal of virology 1996;70(5):2883-93.
1996: Guey Chuen Perng; Susan M Slanina; Homayon Ghiasi; Anthony B Nesburn; Steven L Wechsler
A 371-nucleotide region between the herpes simplex virus type 1 (HSV-1) LAT promoter and the 2-kilobase LAT is not essential for efficient spontaneous reactivation of latent HSV-1.
Journal of virology 1996;70(3):2014-8.
1996: Homayon Ghiasi; Anthony B Nesburn; Steven L Wechsler
Vaccination with a cocktail of seven recombinantly expressed HSV-1 glycoproteins protects against ocular HSV-1 challenge more efficiently than vaccination with any individual glycoprotein.
Vaccine 1996;14(2):107-12.
1996: Guey Chuen Perng; Homayon Ghiasi; Susan M Slanina; Anthony B Nesburn; Steven L Wechsler
The spontaneous reactivation function of the herpes simplex virus type 1 LAT gene resides completely within the first 1.5 kilobases of the 8.3-kilobase primary transcript.
Journal of virology 1996;70(2):976-84.
1996: Guey Chuen Perng; Kulkanya Chokephaibulkit; R L Thompson; N M Sawtell; Susan M Slanina; Homayon Ghiasi; Anthony B Nesburn; Steven L Wechsler
The region of the herpes simplex virus type 1 LAT gene that is colinear with the ICP34.5 gene is not involved in spontaneous reactivation.
Journal of virology 1996;70(1):282-91.
1995: Homayon Ghiasi; Steve Cai; Susan M Slanina; Anthony B Nesburn; Steven L Wechsler
Vaccination of mice with herpes simplex virus type 1 glycoprotein D DNA produces low levels of protection against lethal HSV-1 challenge.
Antiviral research 1995;28(2):147-57.
1995: Homayon Ghiasi; S Bahri; Anthony B Nesburn; Steven L Wechsler
Protection against herpes simplex virus-induced eye disease after vaccination with seven individually expressed herpes simplex virus 1 glycoproteins.
Investigative ophthalmology & visual science 1995;36(7):1352-60.
1995: Guey Chuen Perng; R L Thompson; N M Sawtell; W E Taylor; Susan M Slanina; Homayon Ghiasi; Ravi Kaiwar; Anthony B Nesburn; Steven L Wechsler
An avirulent ICP34.5 deletion mutant of herpes simplex virus type 1 is capable of in vivo spontaneous reactivation.
Journal of virology 1995;69(5):3033-41.
1995: Anthony B Nesburn; S Bahri; J Salz; Yaron S Rabinowitz; Ezra Maguen; J Hofbauer; M Berlin; J I Macy
Keratoconus detected by videokeratography in candidates for photorefractive keratectomy.
Journal of refractive surgery (Thorofare, N.J. : 1995) 1995;11(3):194-201.
1995: Homayon Ghiasi; Steven L Wechsler; Ravi Kaiwar; Anthony B Nesburn; F M Hofman
Local expression of tumor necrosis factor alpha and interleukin-2 correlates with protection against corneal scarring after ocular challenge of vaccinated mice with herpes simplex virus type 1.
Journal of virology 1995;69(1):334-40.
1994: Guey Chuen Perng; E C Dunkel; P A Geary; Susan M Slanina; Homayon Ghiasi; Ravi Kaiwar; Anthony B Nesburn; Steven L Wechsler
The latency-associated transcript gene of herpes simplex virus type 1 (HSV-1) is required for efficient in vivo spontaneous reactivation of HSV-1 from latency.
Journal of virology 1994;68(12):8045-55.
1994: Ezra Maguen; J J Salz; Anthony B Nesburn; C Warren; J I Macy; T Papaioannou; J Hofbauer; M S Berlin
Results of excimer laser photorefractive keratectomy for the correction of myopia.
Ophthalmology 1994;101(9):1548-56; discussion 1556-7.
1994: Anthony B Nesburn; R L Burke; Homayon Ghiasi; Susan M Slanina; S Bahri; Steven L Wechsler
Vaccine therapy for ocular herpes simplex virus (HSV) infection: periocular vaccination reduces spontaneous ocular HSV type 1 shedding in latently infected rabbits.
Journal of virology 1994;68(8):5084-92.
1994: Ezra Maguen; I R Rosner; P Caroline; J I Macy; Anthony B Nesburn
A retrospective study of disposable extended wear lenses in 100 patients: year 3.
The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc 1994;20(3):179-82.
1994: Guey Chuen Perng; J C Zwaagstra; Homayon Ghiasi; Ravi Kaiwar; Donald J Brown; Anthony B Nesburn; Steven L Wechsler
Similarities in regulation of the HSV-1 LAT promoter in corneal and neuronal cells.
Investigative ophthalmology & visual science 1994;35(7):2981-9.
1994: Ezra Maguen; Anthony B Nesburn; T Papaioannou; J J Salz; J I Macy; C Warren
Effect of nitrogen flow on recovery of vision after excimer laser photorefractive keratectomy without nitrogen flow.
Journal of refractive and corneal surgery 1994;10(3):321-6.
1994: Homayon Ghiasi; Susan M Slanina; Anthony B Nesburn; Steven L Wechsler
Characterization of baculovirus-expressed herpes simplex virus type 1 glycoprotein K.
Journal of virology 1994;68(4):2347-54.
1994: Homayon Ghiasi; Ravi Kaiwar; Anthony B Nesburn; Susan M Slanina; Steven L Wechsler
Expression of seven herpes simplex virus type 1 glycoproteins (gB, gC, gD, gE, gG, gH, and gI): comparative protection against lethal challenge in mice.
Journal of virology 1994;68(4):2118-26.
1994: Guey Chuen Perng; Homayon Ghiasi; Ravi Kaiwar; Anthony B Nesburn; Steven L Wechsler
An improved method for cloning portions of the repeat regions of herpes simplex virus type 1.
Journal of virological methods 1994;46(2):111-6.
1994: Homayon Ghiasi; Ravi Kaiwar; Susan M Slanina; Anthony B Nesburn; Steven L Wechsler
Expression and characterization of baculovirus expressed herpes simplex virus type 1 glycoprotein L.
Archives of virology 1994;138(3-4):199-212.
1993: J J Salz; Ezra Maguen; Anthony B Nesburn; C Warren; J I Macy; J D Hofbauer; T Papaioannou; M Berlin
A two-year experience with excimer laser photorefractive keratectomy for myopia.
Ophthalmology 1993;100(6):873-82.
1993: Yaron S Rabinowitz; Anthony B Nesburn; Peter J McDonnell
Videokeratography of the fellow eye in unilateral keratoconus.
Ophthalmology 1993;100(2):181-6.
1992: Ezra Maguen; I Rosner; P Caroline; J I Macy; Anthony B Nesburn
A retrospective study of disposable extended wear lenses in 100 patients: year 2.
The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc 1992;18(4):229-31.
1992: Homayon Ghiasi; Ravi Kaiwar; Anthony B Nesburn; Steven L Wechsler
Baculovirus-expressed glycoprotein G of herpes simplex virus type 1 partially protects vaccinated mice against lethal HSV-1 challenge.
Virology 1992;190(1):233-9.
1992: Ezra Maguen; P Caroline; I R Rosner; J I Macy; Anthony B Nesburn
The use of the SoftPerm lens for the correction of irregular astigmatism.
The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc 1992;18(3):173-6.
1992: J J Salz; Ezra Maguen; J I Macy; T Papaioannou; J Hofbauer; Anthony B Nesburn
One-year results of excimer laser photorefractive keratectomy for myopia.
Refractive & corneal surgery 1992;8(4):269-73.
1992: Homayon Ghiasi; Ravi Kaiwar; Anthony B Nesburn; Susan M Slanina; Steven L Wechsler
Baculovirus-expressed glycoprotein E (gE) of herpes simplex virus type-1 (HSV-1) protects mice against lethal intraperitoneal and lethal ocular HSV-1 challenge.
Virology 1992;188(2):469-76.
1992: Homayon Ghiasi; Ravi Kaiwar; Anthony B Nesburn; Steven L Wechsler
Baculovirus expressed herpes simplex virus type 1 glycoprotein C protects mice from lethal HSV-1 infection.
Antiviral research 1992;18(3-4):291-302.
1992: Homayon Ghiasi; Ravi Kaiwar; Anthony B Nesburn; Steven L Wechsler
Expression of herpes simplex virus type 1 glycoprotein I in baculovirus: preliminary biochemical characterization and protection studies.
Journal of virology 1992;66(4):2505-9.
1992: Homayon Ghiasi; Ravi Kaiwar; Anthony B Nesburn; Steven L Wechsler
Baculovirus-expressed glycoprotein H of herpes simplex virus type 1 (HSV-1) induces neutralizing antibody and delayed type hypersensitivity responses, but does not protect immunized mice against lethal HSV-1 challenge.
The Journal of general virology 1992;73 ( Pt 3)():719-22.
1992: Homayon Ghiasi; Ravi Kaiwar; Anthony B Nesburn; Steven L Wechsler
Expression of herpes simplex virus type 1 glycoprotein B in insect cells. Initial analysis of its biochemical and immunological properties.
Virus research 1992;22(1):25-39.
1991: Ezra Maguen; J C Tsai; M Martinez; I Rosner; P C Cot; J I Macy; Anthony B Nesburn
A retrospective study of disposable extended-wear lenses in 100 patients.
Ophthalmology 1991;98(11):1685-9.
1991: Homayon Ghiasi; Anthony B Nesburn; Steven L Wechsler
Cell surface expression of herpes simplex virus type 1 glycoprotein H in recombinant baculovirus-infected cells.
Virology 1991;185(1):187-94.
1991: J C Zwaagstra; Homayon Ghiasi; Anthony B Nesburn; Steven L Wechsler
Identification of a major regulatory sequence in the latency associated transcript (LAT) promoter of herpes simplex virus type 1 (HSV-1).
Virology 1991;182(1):287-97.
1991: Ezra Maguen; M Martinez; I R Rosner; P Caroline; J Macy; Anthony B Nesburn
The use of Saturn II lenses in keratoconus.
The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc 1991;17(1):41-3.
1991: Homayon Ghiasi; Anthony B Nesburn; Ravi Kaiwar; Steven L Wechsler
Immunoselection of recombinant baculoviruses expressing high levels of biologically active herpes simplex virus type 1 glycoprotein D.
Archives of virology 1991;121(1-4):163-78.
1990: J C Zwaagstra; Homayon Ghiasi; Susan M Slanina; Anthony B Nesburn; S C Wheatley; K Lillycrop; J Wood; D S Latchman; K Patel; Steven L Wechsler
Activity of herpes simplex virus type 1 latency-associated transcript (LAT) promoter in neuron-derived cells: evidence for neuron specificity and for a large LAT transcript.
Journal of virology 1990;64(10):5019-28.
1990: Anthony B Nesburn; Homayon Ghiasi; Steven L Wechsler
Ocular safety and efficacy of an HSV-1 gD vaccine during primary and latent infection.
Investigative ophthalmology & visual science 1990;31(8):1497-502.
1989: J Zwaagstra; Homayon Ghiasi; Anthony B Nesburn; Steven L Wechsler
In vitro promoter activity associated with the latency-associated transcript gene of herpes simplex virus type 1.
The Journal of general virology 1989;70 ( Pt 8)():2163-9.
1989: Ezra Maguen; M Martinez; Warren Grundfest; T Papaioannou; M Berlin; Anthony B Nesburn
Excimer laser ablation of the human lens at 308 nm with a fiber delivery system.
Journal of cataract and refractive surgery 1989;15(4):409-14.
1989: Steven L Wechsler; Anthony B Nesburn; J Zwaagstra; Homayon Ghiasi
Sequence of the latency-related gene of herpes simplex virus type 1.
Virology 1989;168(1):168-72.
1988: Steven L Wechsler; Anthony B Nesburn; R Watson; Susan M Slanina; Homayon Ghiasi
Fine mapping of the major latency-related RNA of herpes simplex virus type 1 in humans.
The Journal of general virology 1988;69 ( Pt 12)():3101-6.
1988: Steven L Wechsler; Anthony B Nesburn; R Watson; Susan M Slanina; Homayon Ghiasi
Fine mapping of the latency-related gene of herpes simplex virus type 1: alternative splicing produces distinct latency-related RNAs containing open reading frames.
Journal of virology 1988;62(11):4051-8.
1986: Ezra Maguen; J Isitt; S Pinhas; Anthony B Nesburn
Extraction of soluble proteins reduces rejection in rabbit porcine corneal xenografts.
Cornea 1986;5(3):163-6.
1985: D E Willey; M D Smith; Anthony B Nesburn; Melvin D Trousdale
Sequential analysis of antibody responses in serum, aqueous humor and tear film during latent and induced recurrent HSV infections.
Current eye research 1985;4(12):1235-40.
1985: Ezra Maguen; Anthony B Nesburn; N Jackman; J I Macy
Broken semiflexible intraocular lens implant.
American journal of ophthalmology 1985;99(2):170-2.
1984: Ezra Maguen; Anthony B Nesburn; S M Verity; I R Rosner
Myopic extended wear contact lenses in 100 patients: a retrospective study.
The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc 1984;10(4):335-40.
1984: Melvin D Trousdale; Anthony B Nesburn; D E Willey; H Taaid
Efficacy of BW759 (9-[[2-hydroxy-1(hydroxymethyl)ethoxy]methyl]guanine) against herpes simplex virus type 1 keratitis in rabbits.
Current eye research 1984;3(8):1007-15.
1984: D E Willey; Melvin D Trousdale; Anthony B Nesburn
Reactivation of murine latent HSV infection by epinephrine iontophoresis.
Investigative ophthalmology & visual science 1984;25(8):945-50.
1984: D E Willey; Ezra Maguen; S Pinhas; S M Verity; Anthony B Nesburn
Antibody response following implantation of xenogenic lenticules.
Cornea 1984;3(1):33-6.
1984: Ezra Maguen; Anthony B Nesburn; J I Macy
Combined use of sodium hyaluronate and tissue adhesive in penetrating keratoplasty of corneal perforations.
Ophthalmic surgery 1984;15(1):55-7.
1983: Ezra Maguen; S Pinhas; S M Verity; Anthony B Nesburn
Keratophakia with lyophilized cornea lathed at room temperature: new techniques and experimental surgical results.
Ophthalmic surgery 1983;14(9):759-62.
1983: Anthony B Nesburn; S Mandelbaum; D E Willey; Melvin D Trousdale; Ezra Maguen; D E Ward
A specular microscopic viewing system for donor corneas.
Ophthalmology 1983;90(6):686-91.
1983: Anthony B Nesburn; D E Willey; Melvin D Trousdale
Effect of intensive acyclovir therapy during artificial reactivation of latent herpes simplex virus.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1983;172(3):316-23.
1983: Ezra Maguen; G Espinosa; I R Rosner; Anthony B Nesburn
Long-term wear of Polycon contact lenses in keratoconus.
The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc 1983;9(1):57-9.
1982: Ezra Maguen; S P Azen; S Pinhas; R A Villaseñor; Anthony B Nesburn
Evaluation of sources of variation on the accuracy and reproducibility of microkeratome sections with the modified artificial anterior chamber.
Ophthalmic surgery 1982;13(3):217-20.