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Richard Nettles

Research Profile

Disorders

Procedures

Highly Active Antiretroviral Therapy

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HIV-1
HIV

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Chemicals & Drugs

Physiology

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Publications

TOP 3
Jonathan Brown; Caly Chien; Andrew Dennis; WJ Doll; Richard E Nettles; Richard Page; Erik Sandefer; Peter Timmins; Li Zhu; Dennis M Grasela
Compartmental absorption modeling and site of absorption studies to determine feasibility of an extended-release formulation of an HIV-1 attachment inhibitor phosphate ester prodrug.
Richard E Nettles; Neelanjana Ray; Dirk Schürmann; Michele Stonier; Megan Wind-Rotolo; Li Zhu; Richard Bertz; Ih Chang; Caly Chien; George J Hanna; Shu-Pang Huang; Mark Krystal; Dennis Grasela
Pharmacodynamics, safety, and pharmacokinetics of BMS-663068, an oral HIV-1 attachment inhibitor in HIV-1-infected subjects.
Justin R Bailey; Ahmad R Sedaghat; Tara L Kieffer; Timothy Brennan; Patricia K Lee; Megan Wind-Rotolo; Christine M Haggerty; Ashrit R Kamireddi; Yi Liu; Jessica Lee; Deborah Persaud; Joel E Gallant; Joseph Cofrancesco; Thomas C Quinn; Claus O Wilke; Stuart C Ray; Janet D Siliciano; Richard E Nettles; Robert Siliciano
Residual human immunodeficiency virus type 1 viremia in some patients on antiretroviral therapy is dominated by a small number of invariant clones rarely found in circulating CD4+ T cells.

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All Publications

2013: Jonathan Brown; Caly Chien; Andrew Dennis; WJ Doll; Richard E Nettles; Richard Page; Erik Sandefer; Peter Timmins; Li Zhu; Dennis M Grasela
Compartmental absorption modeling and site of absorption studies to determine feasibility of an extended-release formulation of an HIV-1 attachment inhibitor phosphate ester prodrug.
Journal of pharmaceutical sciences 2013;102(6):1742-51.
2012: Richard E Nettles; Neelanjana Ray; Dirk Schürmann; Michele Stonier; Megan Wind-Rotolo; Li Zhu; Richard Bertz; Ih Chang; Caly Chien; George J Hanna; Shu-Pang Huang; Mark Krystal; Dennis Grasela
Pharmacodynamics, safety, and pharmacokinetics of BMS-663068, an oral HIV-1 attachment inhibitor in HIV-1-infected subjects.
The Journal of infectious diseases 2012;206(7):1002-11.
2006: Justin R Bailey; Ahmad R Sedaghat; Tara L Kieffer; Timothy Brennan; Patricia K Lee; Megan Wind-Rotolo; Christine M Haggerty; Ashrit R Kamireddi; Yi Liu; Jessica Lee; Deborah Persaud; Joel E Gallant; Joseph Cofrancesco; Thomas C Quinn; Claus O Wilke; Stuart C Ray; Janet D Siliciano; Richard E Nettles; Robert Siliciano
Residual human immunodeficiency virus type 1 viremia in some patients on antiretroviral therapy is dominated by a small number of invariant clones rarely found in circulating CD4+ T cells.
Journal of virology 2006;80(13):6441-57.
2006: Patricia K Lee; Tara L Kieffer; Robert Siliciano; Richard E Nettles
HIV-1 viral load blips are of limited clinical significance.
The Journal of antimicrobial chemotherapy 2006;57(5):803-5.
2006: Richard E Nettles; Tara L Kieffer; Teresa Parsons; James Johnson; Joseph Cofrancesco; Joel E Gallant; Kathryn Carson; Robert Siliciano; Charles Flexner
Marked intraindividual variability in antiretroviral concentrations may limit the utility of therapeutic drug monitoring.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2006;42(8):1189-96.
2006: Richard E Nettles; Tara L Kieffer
Update on HIV-1 viral load blips.
Current opinion in HIV and AIDS 2006;1(2):157-61.
2005: Richard E Nettles; Tara L Keiffer; Joseph Cofrancesco; Joel E Gallant; Thomas C Quinn; J Brooks Jackson; Charles Flexner; Kathryn Carson; Albert W Wu; Robert Siliciano
Psychological distress and physical pain appear to have no short-term adverse impact on plasma HIV-1 RNA levels in patients on successful HAART.
HIV clinical trials 2005;6(5):262-71.
2005: Tara L Kieffer; Richard E Nettles
Clinical implications of HIV viral load blips.
The Hopkins HIV report : a bimonthly newsletter for healthcare providers / Johns Hopkins University AIDS Service 2005;17(4):8-9.
2005: Daphne Monie; Rachel P Simmons; Richard E Nettles; Tara L Kieffer; Yan Zhou; Haili Zhang; Sharon Karmon; Roxann G Ingersoll; Karen Chadwick; Hao Zhang; Joseph B Margolick; Thomas C Quinn; Stuart C Ray; Megan Wind-Rotolo; Michael Miller; Deborah Persaud; Robert Siliciano
A novel assay allows genotyping of the latent reservoir for human immunodeficiency virus type 1 in the resting CD4+ T cells of viremic patients.
Journal of virology 2005;79(8):5185-202.
2005: Richard E Nettles; Tara L Kieffer; Patty Kwon; Daphne Monie; Yefei Han; Teresa Parsons; Joseph Cofrancesco; Joel E Gallant; Thomas C Quinn; J Brooks Jackson; Charles Flexner; Kathryn Carson; Stuart C Ray; Deborah Persaud; Robert Siliciano
Intermittent HIV-1 viremia (Blips) and drug resistance in patients receiving HAART.
JAMA : the journal of the American Medical Association 2005;293(7):817-29.
2005: Tara L Kieffer; Patty Kwon; Richard E Nettles; Yefei Han; Stuart C Ray; Robert Siliciano
G-->A hypermutation in protease and reverse transcriptase regions of human immunodeficiency virus type 1 residing in resting CD4+ T cells in vivo.
Journal of virology 2005;79(3):1975-80.
2004: Richard E Nettles; Tara L Kieffer; Rachel P Simmons; Joseph Cofrancesco; Richard D Moore; Joel E Gallant; Deborah Persaud; Robert Siliciano
Genotypic resistance in HIV-1-infected patients with persistently detectable low-level viremia while receiving highly active antiretroviral therapy.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2004;39(7):1030-7.
2004: Tara L Kieffer; Mariel M Finucane; Richard E Nettles; Thomas C Quinn; Karl W Broman; Stuart C Ray; Deborah Persaud; Robert Siliciano
Genotypic analysis of HIV-1 drug resistance at the limit of detection: virus production without evolution in treated adults with undetectable HIV loads.
The Journal of infectious diseases 2004;189(8):1452-65.
2004: Richard E Nettles; Dana Mazo; Karla Alwood; Regina Gachuhi; Gina Maltas; Karen A Wendel; Wendy A Cronin; Nancy Hooper; William R Bishai; Timothy R Sterling
Risk factors for relapse and acquired rifamycin resistance after directly observed tuberculosis treatment: a comparison by HIV serostatus and rifamycin use.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2004;38(5):731-6.
2003: Richard E Nettles; Lynette S Nichols; Katherine Marie Bell-McGuinn; Matthew R Pipeling; Paul J Scheel; William G Merz
Successful treatment of Trichosporon mucoides infection with fluconazole in a heart and kidney transplant recipient.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2003;36(4):E63-6.