FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Elizabeth Neufeld

Research Profile

Chemicals & Drugs

Disorders

Physiology

Mutation

Concepts & Ideas

Molecular Sequence Data

Anatomy

Living Beings

Mouse
Dogs

Procedures

Polymerase Chain Reaction

Co-author Network

Publications

TOP 3
Elizabeth F Neufeld
From serendipity to therapy.
Kazuhiro Ohmi; Hui-Zhi Zhao; Elizabeth F Neufeld
Defects in the medial entorhinal cortex and dentate gyrus in the mouse model of Sanfilippo syndrome type B.
Kazuhiro Ohmi; Lili C Kudo; Sergey Ryazantsev; Hui-Zhi Zhao; Stanislav Karsten; Elizabeth F Neufeld
Sanfilippo syndrome type B, a lysosomal storage disease, is also a tauopathy.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Elizabeth Neufeld (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2011: Elizabeth F Neufeld
From serendipity to therapy.
Annual review of biochemistry 2011;80():1-15.
2011: Kazuhiro Ohmi; Hui-Zhi Zhao; Elizabeth F Neufeld
Defects in the medial entorhinal cortex and dentate gyrus in the mouse model of Sanfilippo syndrome type B.
PloS one 2011;6(11):e27461.
2009: Kazuhiro Ohmi; Lili C Kudo; Sergey Ryazantsev; Hui-Zhi Zhao; Stanislav Karsten; Elizabeth F Neufeld
Sanfilippo syndrome type B, a lysosomal storage disease, is also a tauopathy.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(20):8332-7.
2008: Chi-Hong B Chen; Kenneth R Dellamaggiore; Christopher P Ouellette; Cecilia D Sedano; Meikana Lizadjohry; George A Chernis; Michelle Gonzales; Francis E Baltasar; Audrey L Fan; Rachel Myerowitz; Elizabeth F Neufeld
Aptamer-based endocytosis of a lysosomal enzyme.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(41):15908-13.
2007: Sergey Ryazantsev; Wei-Hong Yu; Hui-Zhi Zhao; Elizabeth F Neufeld; Kazuhiro Ohmi
Lysosomal accumulation of SCMAS (subunit c of mitochondrial ATP synthase) in neurons of the mouse model of mucopolysaccharidosis III B.
Molecular genetics and metabolism 2007;90(4):393-401.
2005: Maria C Jordan; Yi Zheng; Sergey Ryazantsev; Nora Rozengurt; Kenneth P Roos; Elizabeth F Neufeld
Cardiac manifestations in the mouse model of mucopolysaccharidosis I.
Molecular genetics and metabolism 2005;86(1-2):233-43.
2004: Yi Zheng; Sergey Ryazantsev; Kazuhiro Ohmi; Hui-Zhi Zhao; Nora Rozengurt; Donald B Kohn; Elizabeth F Neufeld
Retrovirally transduced bone marrow has a therapeutic effect on brain in the mouse model of mucopolysaccharidosis IIIB.
Molecular genetics and metabolism 2004;82(4):286-95.
2003: Yi Zheng; Nora Rozengurt; Sergey Ryazantsev; Donald B Kohn; Noriko Satake; Elizabeth F Neufeld
Treatment of the mouse model of mucopolysaccharidosis I with retrovirally transduced bone marrow.
Molecular genetics and metabolism 2003;79(4):233-44.
2003: Kazuhiro Ohmi; David S Greenberg; Kavitha S Rajavel; Sergey Ryazantsev; Hong Hua Li; Elizabeth F Neufeld
Activated microglia in cortex of mouse models of mucopolysaccharidoses I and IIIB.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(4):1902-7.
2002: Hong Hua Li; Hui-Zhi Zhao; Elizabeth F Neufeld; Yan Cai; Fernando Gomez-Pinilla
Attenuated plasticity in neurons and astrocytes in the mouse model of Sanfilippo syndrome type B.
Journal of neuroscience research 2002;69(1):30-8.
2001: K S Rajavel; Elizabeth F Neufeld
Nonsense-mediated decay of human HEXA mRNA.
Molecular and cellular biology 2001;21(16):5512-9.
2001: Emil D Kakkis; Joseph Muenzer; G E Tiller; L Waber; J Belmont; M Passage; B Izykowski; J Phillips; Robin W Doroshow; Irwin Walot; R Hoft; Elizabeth F Neufeld
Enzyme-replacement therapy in mucopolysaccharidosis I.
The New England journal of medicine 2001;344(3):182-8.
2001: Elizabeth F Neufeld; A d'Azzo
Biosynthesis of normal and mutant beta-hexosaminidases.
Advances in genetics 2001;44():165-71.
2000: Wei-Hong Yu; KW Zhao; Sergey Ryazantsev; Nora Rozengurt; Elizabeth F Neufeld
Short-term enzyme replacement in the murine model of Sanfilippo syndrome type B.
Molecular genetics and metabolism 2000;71(4):573-80.
2000: KW Zhao; Elizabeth F Neufeld
Purification and characterization of recombinant human alpha-N-acetylglucosaminidase secreted by Chinese hamster ovary cells.
Protein expression and purification 2000;19(1):202-11.
2000: L Ruth; David Eisenberg; Elizabeth F Neufeld
alpha-L-iduronidase forms semi-crystalline spherulites with amyloid-like properties.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 4):524-8.
1999: Hong Hua Li; Wei-Hong Yu; Nora Rozengurt; Hui-Zhi Zhao; Karen M Lyons; Stephan Anagnostaras; Michael S Fanselow; Kunihiko Suzuki; marie T vanier; Elizabeth F Neufeld
Mouse model of Sanfilippo syndrome type B produced by targeted disruption of the gene encoding alpha-N-acetylglucosaminidase.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(25):14505-10.
1998: A Schmidtchen; D Greenberg; H G Zhao; Hong Hua Li; Y Huang; P Tieu; Hui-Zhi Zhao; S Cheng; Z Zhao; Chester Whitley; P Di Natale; Elizabeth F Neufeld
NAGLU mutations underlying Sanfilippo syndrome type B.
American journal of human genetics 1998;62(1):64-9.
1997: KW Zhao; Kym F Faull; Emil D Kakkis; Elizabeth F Neufeld
Carbohydrate structures of recombinant human alpha-L-iduronidase secreted by Chinese hamster ovary cells.
The Journal of biological chemistry 1997;272(36):22758-65.
1996: E D Kakkis; M F McEntee; A Schmidtchen; Elizabeth F Neufeld; D A Ward; R E Gompf; Stephen A Kania; C Bedolla; S L Chien; R M Shull
Long-term and high-dose trials of enzyme replacement therapy in the canine model of mucopolysaccharidosis I.
Biochemical and molecular medicine 1996;58(2):156-67.
1996: H G Zhao; Hong Hua Li; G Bach; A Schmidtchen; Elizabeth F Neufeld
The molecular basis of Sanfilippo syndrome type B.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(12):6101-5.
1995: P T Tieu; Gideon Bach; A Matynia; M Hwang; Elizabeth F Neufeld
Four novel mutations underlying mild or intermediate forms of alpha-L-iduronidase deficiency (MPS IS and MPS IH/S).
Human mutation 1995;6(1):55-9.
1994: R M Shull; E D Kakkis; M F McEntee; Stephen A Kania; A J Jonas; Elizabeth F Neufeld
Enzyme replacement in a canine model of Hurler syndrome.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(26):12937-41.
1994: K P Menon; Elizabeth F Neufeld
Evidence for degradation of mRNA encoding alpha-L-iduronidase in Hurler fibroblasts with premature termination alleles.
Cellular and molecular biology (Noisy-le-Grand, France) 1994;40(7):999-1005.
1994: E D Kakkis; A Matynia; A J Jonas; Elizabeth F Neufeld
Overexpression of the human lysosomal enzyme alpha-L-iduronidase in Chinese hamster ovary cells.
Protein expression and purification 1994;5(3):225-32.
1994: P T Tieu; K Menon; Elizabeth F Neufeld
A mutant stop codon (TAG) in the IDUA gene is used as an acceptor splice site in a patient with Hurler syndrome (MPS IH).
Human mutation 1994;3(3):333-6.
1993: Gideon Bach; S M Moskowitz; P T Tieu; A Matynia; Elizabeth F Neufeld
Molecular analysis of Hurler syndrome in Druze and Muslim Arab patients in Israel: multiple allelic mutations of the IDUA gene in a small geographic area.
American journal of human genetics 1993;53(2):330-8.
1993: S M Moskowitz; P T Tieu; Elizabeth F Neufeld
A deletion/insertion mutation in the IDUA gene in a Libyan Jewish patient with Hurler syndrome (mucopolysaccharidosis IH).
Human mutation 1993;2(1):71-3.
1993: S M Moskowitz; P T Tieu; Elizabeth F Neufeld
Mutation in Scheie syndrome (MPS IS): a G-->A transition creates new splice site in intron 5 of one IDUA allele.
Human mutation 1993;2(2):141-4.
1992: K P Menon; P T Tieu; Elizabeth F Neufeld
Architecture of the canine IDUA gene and mutation underlying canine mucopolysaccharidosis I.
Genomics 1992;14(3):763-8.
1992: L J Stoltzfus; B Sosa-Pineda; S M Moskowitz; K P Menon; B Dlott; L Hooper; David B Teplow; R M Shull; Elizabeth F Neufeld
Cloning and characterization of cDNA encoding canine alpha-L-iduronidase. mRNA deficiency in mucopolysaccharidosis I dog.
The Journal of biological chemistry 1992;267(10):6570-5.
1992: Joseph Muenzer; Elizabeth F Neufeld; G Constantopoulos; Rafael C Caruso; Muriel I Kaiser-Kupfer; A Pikus; J Danoff; R R Berry; H D McDonald; J N Thompson
Attempted enzyme replacement using human amnion membrane implantations in mucopolysaccharidoses.
Journal of inherited metabolic disease 1992;15(1):25-37.
1991: B H Paw; L C Wood; Elizabeth F Neufeld
A third mutation at the CpG dinucleotide of codon 504 and a silent mutation at codon 506 of the HEX A gene.
American journal of human genetics 1991;48(6):1139-46.
1990: B Dlott; A d'Azzo; D V Quon; Elizabeth F Neufeld
Two mutations produce intron insertion in mRNA and elongated beta-subunit of human beta-hexosaminidase.
The Journal of biological chemistry 1990;265(29):17921-7.
1990: B H Paw; P T Tieu; M M Kaback; J Lim; Elizabeth F Neufeld
Frequency of three Hex A mutant alleles among Jewish and non-Jewish carriers identified in a Tay-Sachs screening program.
American journal of human genetics 1990;47(4):698-705.
1990: L C Wood; Elizabeth F Neufeld
A cystic fibrosis phenotype in cells cultured from sweat gland secretory coil. Altered kinetics of 36Cl efflux.
The Journal of biological chemistry 1990;265(22):12796-800.
1990: B H Paw; S M Moskowitz; Nancy Uhrhammer; N Wright; M M Kaback; Elizabeth F Neufeld
Juvenile GM2 gangliosidosis caused by substitution of histidine for arginine at position 499 or 504 of the alpha-subunit of beta-hexosaminidase.
The Journal of biological chemistry 1990;265(16):9452-7.
1989: M M Lau; Elizabeth F Neufeld
A frameshift mutation in a patient with Tay-Sachs disease causes premature termination and defective intracellular transport of the alpha-subunit of beta-hexosaminidase.
The Journal of biological chemistry 1989;264(35):21376-80.
1989: Elizabeth F Neufeld
Natural history and inherited disorders of a lysosomal enzyme, beta-hexosaminidase.
The Journal of biological chemistry 1989;264(19):10927-30.
1989: B H Paw; M M Kaback; Elizabeth F Neufeld
Molecular basis of adult-onset and chronic GM2 gangliosidoses in patients of Ashkenazi Jewish origin: substitution of serine for glycine at position 269 of the alpha-subunit of beta-hexosaminidase.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(7):2413-7.
1989: D V Quon; Richard L Proia; A V Fowler; J Bleibaum; Elizabeth F Neufeld
Proteolytic processing of the beta-subunit of the lysosomal enzyme, beta-hexosaminidase, in normal human fibroblasts.
The Journal of biological chemistry 1989;264(6):3380-4.
1988: L E Little; M M Lau; D V Quon; A V Fowler; Elizabeth F Neufeld
Proteolytic processing of the alpha-chain of the lysosomal enzyme, beta-hexosaminidase, in normal human fibroblasts.
The Journal of biological chemistry 1988;263(9):4288-92.
1988: B H Paw; Elizabeth F Neufeld
Normal transcription of the beta-hexosaminidase alpha-chain gene in the Ashkenazi Tay-Sachs mutation.
The Journal of biological chemistry 1988;263(6):3012-5.
1986: E E Grebner; D A Mansfield; S S Raghavan; Edwin H Kolodny; A d'Azzo; Elizabeth F Neufeld; L G Jackson
Two abnormalities of hexosaminidase A in clinically normal individuals.
American journal of human genetics 1986;38(4):505-14.
1985: R Myerowitz; R Piekarz; Elizabeth F Neufeld; T B Shows; Kunihiko Suzuki
Human beta-hexosaminidase alpha chain: coding sequence and homology with the beta chain.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(23):7830-4.
1985: G Constantopoulos; R M Shull; N Hastings; Elizabeth F Neufeld
Neurochemical characterization of canine alpha-L-iduronidase deficiency disease (model of human mucopolysaccharidosis I).
Journal of neurochemistry 1985;45(4):1213-7.
1984: A d'Azzo; Richard L Proia; Edwin H Kolodny; M M Kaback; Elizabeth F Neufeld
Faulty association of alpha- and beta-subunits in some forms of beta-hexosaminidase A deficiency.
The Journal of biological chemistry 1984;259(17):11070-4.
1984: Richard L Proia; A d'Azzo; Elizabeth F Neufeld
Association of alpha- and beta-subunits during the biosynthesis of beta-hexosaminidase in cultured human fibroblasts.
The Journal of biological chemistry 1984;259(5):3350-4.
1984: R M Shull; R G Helman; E Spellacy; G Constantopoulos; R J Munger; Elizabeth F Neufeld
Morphologic and biochemical studies of canine mucopolysaccharidosis I.
The American journal of pathology 1984;114(3):487-95.
1983: E Spellacy; R M Shull; G Constantopoulos; Elizabeth F Neufeld
A canine model of human alpha-L-iduronidase deficiency.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(19):6091-5.
1983: G G Sahagian; Elizabeth F Neufeld
Biosynthesis and turnover of the mannose 6-phosphate receptor in cultured Chinese hamster ovary cells.
The Journal of biological chemistry 1983;258(11):7121-8.
1983: R Myerowitz; A R Robbins; Richard L Proia; G G Sahagian; C M Puchalski; Elizabeth F Neufeld
Studies of lysosomal enzyme biosynthesis in cultured cells.
Methods in enzymology 1983;96():729-36.
1982: R M Shull; R J Munger; E Spellacy; C W Hall; G Constantopoulos; Elizabeth F Neufeld
Canine alpha-L-iduronidase deficiency. A model of mucopolysaccharidosis I.
The American journal of pathology 1982;109(2):244-8.
1982: Richard L Proia; Elizabeth F Neufeld
Synthesis of beta-hexosaminidase in cell-free translation and in intact fibroblasts: an insoluble precursor alpha chain in a rare form of Tay-Sachs disease.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(20):6360-4.
1981: M C Willingham; Ira Pastan; G G Sahagian; George W Jourdian; Elizabeth F Neufeld
Morphologic study of the internalization of a lysosomal enzyme by the mannose 6-phosphate receptor in cultured Chinese hamster ovary cells.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(11):6967-71.
1981: R Myerowitz; Elizabeth F Neufeld
Maturation of alpha-L-iduronidase in cultured human fibroblasts.
The Journal of biological chemistry 1981;256(6):3044-8.