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Wolfgang Neuhofer

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Christoph Küper; Hans-Helge Müller; Franz-X Beck; Maria-Luisa Fraek; Wolfgang Neuhofer
Sepsis-induced urinary concentration defect is related to nitric oxide-dependent inactivation of TonEBP/NFAT5, which downregulates renal medullary solute transport proteins and aquaporin-2.
Christoph Aufricht; Wolfgang Neuhofer; Nicholas Topley; Markus Wörnle
Peritoneal infection and inflammation.
Christoph Küper; Franz-X Beck; Wolfgang Neuhofer
NFAT5 contributes to osmolality-induced MCP-1 expression in mesothelial cells.

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2012: Christoph Küper; Hans-Helge Müller; Franz-X Beck; Maria-Luisa Fraek; Wolfgang Neuhofer
Sepsis-induced urinary concentration defect is related to nitric oxide-dependent inactivation of TonEBP/NFAT5, which downregulates renal medullary solute transport proteins and aquaporin-2.
Critical care medicine 2012;40(6):1887-95.
2012: Christoph Aufricht; Wolfgang Neuhofer; Nicholas Topley; Markus Wörnle
Peritoneal infection and inflammation.
Mediators of inflammation 2012;2012():456985.
2012: Christoph Küper; Franz-X Beck; Wolfgang Neuhofer
NFAT5 contributes to osmolality-induced MCP-1 expression in mesothelial cells.
Mediators of inflammation 2012;2012():513015.
2011: Christoph Küper; Helmut Bartels; Franz-X Beck; Wolfgang Neuhofer
Cyclooxygenase-2-dependent phosphorylation of the pro-apoptotic protein Bad inhibits tonicity-induced apoptosis in renal medullary cells.
Kidney international 2011;80(9):938-45.
2010: Wolfgang Neuhofer
Role of NFAT5 in inflammatory disorders associated with osmotic stress.
Current genomics 2010;11(8):584-90.
2009: Wolfgang Neuhofer; David Pittrow
Endothelin receptor selectivity in chronic kidney disease: rationale and review of recent evidence.
European journal of clinical investigation 2009;39 Suppl 2():50-67.
2009: Agnes Machnik; Wolfgang Neuhofer; Jonathan Jantsch; Anke Dahlmann; Tuomas Tammela; Katharina Machura; Joon-Keun Park; Franz-Xaver Beck; Dominik N Müller; Wolfgang Derer; Jennifer Goss; Agata Ziomber; Peter Dietsch; Hubertus Wagner; Nico van Rooijen; Armin Kurtz; Karl F Hilgers; Kari Alitalo; Kai-Uwe Eckardt; Friedrich C Luft; Dontscho Kerjaschki; Jens Titze
Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism.
Nature medicine 2009;15(5):545-52.
2009: Christoph Küper; Daniela Steinert; Maria-Luisa Fraek; Franz-X Beck; Wolfgang Neuhofer
EGF receptor signaling is involved in expression of osmoprotective TonEBP target gene aldose reductase under hypertonic conditions.
American journal of physiology. Renal physiology 2009;296(5):F1100-8.
2009: Wolfgang Neuhofer; Maria-Luisa Fraek; Franz-X Beck
Nitric oxide decreases expression of osmoprotective genes via direct inhibition of TonEBP transcriptional activity.
Pflügers Archiv : European journal of physiology 2009;457(4):831-43.
2009: Daniela Steinert; Christoph Küper; Helmut Bartels; Franz-X Beck; Wolfgang Neuhofer
PGE2 potentiates tonicity-induced COX-2 expression in renal medullary cells in a positive feedback loop involving EP2-cAMP-PKA signaling.
American journal of physiology. Cell physiology 2009;296(1):C75-87.
2008: Wolfgang Neuhofer
Method for diagnosis of a disease involving an anti-endothelin receptor antibody.
Expert opinion on medical diagnostics 2008;2(7):875-8.
2007: Christoph Küper; Helmut Bartels; Maria-Luisa Fraek; Franz-X Beck; Wolfgang Neuhofer
Ectodomain shedding of pro-TGF-alpha is required for COX-2 induction and cell survival in renal medullary cells exposed to osmotic stress.
American journal of physiology. Cell physiology 2007;293(6):C1971-82.
2007: Konstantin Holzapfel; Wolfgang Neuhofer; Helmut Bartels; Maria-Luisa Fraek; Franz-X Beck
Role of focal adhesion kinase (FAK) in renal ischaemia and reperfusion.
Pflügers Archiv : European journal of physiology 2007;455(2):273-82.
2007: Wolfgang Neuhofer; Daniela Steinert; Maria-Luisa Fraek; Franz-X Beck
Prostaglandin E2 stimulates expression of osmoprotective genes in MDCK cells and promotes survival under hypertonic conditions.
The Journal of physiology 2007;583(Pt 1):287-97.
2007: Küper Christoph; Franz-X Beck; Wolfgang Neuhofer
Osmoadaptation of Mammalian cells - an orchestrated network of protective genes.
Current genomics 2007;8(4):209-18.
2006: Wolfgang Neuhofer; D Pittrow
Endothelin in human autoimmune diseases with renal involvement.
Rheumatology (Oxford, England) 2006;45 Suppl 3():iii39-41.
2006: Wolfgang Neuhofer; D Pittrow
Role of endothelin and endothelin receptor antagonists in renal disease.
European journal of clinical investigation 2006;36 Suppl 3():78-88.
2006: Wolfgang Neuhofer; Veit Gülberg; Alexander L Gerbes
Endothelin and endothelin receptor antagonism in portopulmonary hypertension.
European journal of clinical investigation 2006;36 Suppl 3():54-61.
2006: Marlies Michl; Nengtai Ouyang; Maria-Luisa Fraek; Franz-X Beck; Wolfgang Neuhofer
Expression and regulation of alphaB-crystallin in the kidney in vivo and in vitro.
Pflügers Archiv : European journal of physiology 2006;452(4):387-95.
2006: Wolfgang Neuhofer; Franz-X Beck
Survival in hostile environments: strategies of renal medullary cells.
Physiology (Bethesda, Md.) 2006;21():171-80.
2006: Franz-X Beck; Wolfgang Neuhofer
Cell volume regulation in the renal papilla.
Contributions to nephrology 2006;152():181-97.
2005: Wolfgang Neuhofer; Maria-Luisa Fraek; Nengtai Ouyang; Franz-X Beck
Differential expression of heat shock protein 27 and 70 in renal papillary collecting duct and interstitial cells - implications for urea resistance.
The Journal of physiology 2005;564(Pt 3):715-22.
2005: Wolfgang Neuhofer; Monika Vastag; Maria-Luisa Fraek; Franz-X Beck
Effect of ammonium on the expression of osmosensitive genes in Madin-Darby canine kidney cells.
The Journal of physiology 2005;563(Pt 2):497-505.
2005: Franz-X Beck; Wolfgang Neuhofer
Response of renal medullary cells to osmotic stress.
Contributions to nephrology 2005;148():21-34.
2005: M Vastag; Wolfgang Neuhofer; Wolfram Nagel; Franz-X Beck
Ammonium affects tight junctions and the cytoskeleton in MDCK cells.
Pflügers Archiv : European journal of physiology 2005;449(4):384-91.
2005: Wolfgang Neuhofer; Franz-X Beck
Cell survival in the hostile environment of the renal medulla.
Annual review of physiology 2005;67():531-55.
2004: Wolfgang Neuhofer; Konstantin Holzapfel; Maria-Luisa Fraek; Nengtai Ouyang; Jens Lutz; Franz-X Beck
Chronic COX-2 inhibition reduces medullary HSP70 expression and induces papillary apoptosis in dehydrated rats.
Kidney international 2004;65(2):431-41.
2003: Franz-X Beck; Wolfgang Neuhofer; Adolf Dörge; Gerhard Giebisch; Tong Wang
Intracellular Na concentration and Rb uptake in proximal convoluted tubule cells and abundance of Na/K-ATPase alpha1-subunit in NHE3-/- mice.
Pflügers Archiv : European journal of physiology 2003;446(1):100-5.
2002: Wolfgang Neuhofer; Seung Kyoon Woo; Ki Young Na; Rita Grunbein; Won Kun Park; Ohnn Nahm; Franz-X Beck; H Moo Kwon
Regulation of TonEBP transcriptional activator in MDCK cells following changes in ambient tonicity.
American journal of physiology. Cell physiology 2002;283(6):C1604-11.
2002: Wolfgang Neuhofer; Maria-Luisa Fraek; Franz X Beck
Heat shock protein 72, a chaperone abundant in renal papilla, counteracts urea-mediated inhibition of enzymes.
Pflügers Archiv : European journal of physiology 2002;445(1):67-73.
2002: Wolfgang Neuhofer; Helmut Bartels; Maria-Luisa Fraek; Franz-X Beck
Relationship between intracellular ionic strength and expression of tonicity-responsive genes in rat papillary collecting duct cells.
The Journal of physiology 2002;543(Pt 1):147-53.
2001: Wolfgang Neuhofer; K Lugmayr; Maria-Luisa Fraek; Franz-X Beck
Regulated overexpression of heat shock protein 72 protects Madin-Darby canine kidney cells from the detrimental effects of high urea concentrations.
Journal of the American Society of Nephrology : JASN 2001;12(12):2565-71.
2000: Franz-X Beck; Wolfgang Neuhofer; E Müller
Molecular chaperones in the kidney: distribution, putative roles, and regulation.
American journal of physiology. Renal physiology 2000;279(2):F203-15.
2000: Franz-X Beck; R Grünbein; K Lugmayr; Wolfgang Neuhofer
Heat shock proteins and the cellular response to osmotic stress.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2000;10(5-6):303-6.
1999: Wolfgang Neuhofer; E Müller; R Grünbein; K Thurau; Franz-X Beck
Influence of NaCl, urea, potassium and pH on HSP72 expression in MDCK cells.
Pflügers Archiv : European journal of physiology 1999;439(1-2):195-200.
1999: E Müller; Anke Burger-Kentischer; Wolfgang Neuhofer; Maria-Luisa Fraek; J März; K Thurau; Franz-X Beck
Possible involvement of heat shock protein 25 in the angiotensin II-induced glomerular mesangial cell contraction via p38 MAP kinase.
Journal of cellular physiology 1999;181(3):462-9.
1999: Wolfgang Neuhofer; E Müller; Anke Burger-Kentischer; Maria-Luisa Fraek; K Thurau; Franz-X Beck
Inhibition of NaCl-induced heat shock protein 72 expression renders MDCK cells susceptible to high urea concentrations.
Pflügers Archiv : European journal of physiology 1999;437(4):611-6.
1999: Anke Burger-Kentischer; E Müller; Wolfgang Neuhofer; J März; K Thurau; F Beck
Expression of aldose reductase, sorbitol dehydrogenase and Na+/myo-inositol and Na+/Cl-/betaine transporter mRNAs in individual cells of the kidney during changes in the diuretic state.
Pflügers Archiv : European journal of physiology 1999;437(2):248-54.
1998: Anke Burger-Kentischer; E Müller; Wolfgang Neuhofer; J März; K Thurau; Franz-X Beck
Expression of Na+/Cl-/betaine and Na+/myo-inositol transporters, aldose reductase and sorbitol dehydrogenase in macula densa cells of the kidney.
Pflügers Archiv : European journal of physiology 1998;436(5):807-9.
1998: Wolfgang Neuhofer; E Müller; Anke Burger-Kentischer; Franz-X Beck
Hypertonicity affects heat shock protein 27 and F-actin localization in Madin-Darby canine kidney cells.
Kidney international. Supplement 1998;67():S165-7.
1998: E Müller; Anke Burger-Kentischer; Wolfgang Neuhofer; Andreas Schober; Franz-X Beck
Influence of osmotic stress on heat shock proteins 25 and 72 in mouse mesangial cells.
Kidney international. Supplement 1998;67():S162-4.
1998: Anke Burger-Kentischer; E Müller; H G Klein; Andreas Schober; Wolfgang Neuhofer; Franz-X Beck
Cationic amino acid transporter mRNA expression in rat kidney and liver.
Kidney international. Supplement 1998;67():S136-8.
1998: E Müller; Wolfgang Neuhofer; Anke Burger-Kentischer; A Ohno; K Thurau; F Beck
Effects of long-term changes in medullary osmolality on heat shock proteins HSp25, HSP60, HSP72 and HSP73 in the rat kidney.
Pflügers Archiv : European journal of physiology 1998;435(5):705-12.
1998: Wolfgang Neuhofer; E Müller; Anke Burger-Kentischer; Maria-Luisa Fraek; K Thurau; F Beck
Pretreatment with hypertonic NaCl protects MDCK cells against high urea concentrations.
Pflügers Archiv : European journal of physiology 1998;435(3):407-14.
1996: E Müller; Wolfgang Neuhofer; A Ohno; S Rucker; K Thurau; Franz-X Beck
Heat shock proteins HSP25, HSP60, HSP72, HSP73 in isoosmotic cortex and hyperosmotic medulla of rat kidney.
Pflügers Archiv : European journal of physiology 1996;431(4):608-17.