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Pertti Neuvonen

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
93
Backman, Janne
75
Kivistö, Kari
56
Olkkola, Klaus
48
Niemi, Mikko
42
Neuvonen, Mikko
23
Kivistö, KT
22
Laine, Kari
21
Laitila, Jouko
18
Lilja, Jari
14
Wang, Jun-Sheng
12
Ahonen, Jouni
11
Pasanen, Marja
10
Luurila, Harri
9
Kantola, T
9
Kajosaari, Lauri

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Publications

TOP 3
Keskitalo Jenni E; Pasanen Marja K; Neuvonen Pertti J; Niemi Mikko
Different effects of the ABCG2 c.421C>A SNP on the pharmacokinetics of fluvastatin, pravastatin and simvastatin.
Keskitalo Jenni E; Kurkinen Kaisa J; Neuvonen Mikko; Backman Janne T; Neuvonen Pertti J; Niemi Mikko
No significant effect of ABCB1 haplotypes on the pharmacokinetics of fluvastatin, pravastatin, lovastatin, and rosuvastatin.
Keskitalo J E; Zolk O; Fromm M F; Kurkinen K J; Neuvonen P J; Niemi M
ABCG2 polymorphism markedly affects the pharmacokinetics of atorvastatin and rosuvastatin.

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All Publications

2009: Keskitalo Jenni E; Pasanen Marja K; Neuvonen Pertti J; Niemi Mikko
Different effects of the ABCG2 c.421C>A SNP on the pharmacokinetics of fluvastatin, pravastatin and simvastatin.
Pharmacogenomics 2009;10(10):1617-24.
2009: Keskitalo Jenni E; Kurkinen Kaisa J; Neuvonen Mikko; Backman Janne T; Neuvonen Pertti J; Niemi Mikko
No significant effect of ABCB1 haplotypes on the pharmacokinetics of fluvastatin, pravastatin, lovastatin, and rosuvastatin.
British journal of clinical pharmacology 2009;68(2):207-13.
2009: Keskitalo J E; Zolk O; Fromm M F; Kurkinen K J; Neuvonen P J; Niemi M
ABCG2 polymorphism markedly affects the pharmacokinetics of atorvastatin and rosuvastatin.
Clinical pharmacology and therapeutics 2009;86(2):197-203.
2009: Nieminen Tuija H; Hagelberg Nora M; Saari Teijo I; Pertovaara Antti; Neuvonen Mikko; Laine Kari; Neuvonen Pertti J; Olkkola Klaus T
Rifampin greatly reduces the plasma concentrations of intravenous and oral oxycodone.
Anesthesiology 2009;110(6):1371-8.
2009: Xiang Xiaoqiang; Han Yi; Neuvonen Mikko; Pasanen Marja K; Kalliokoski Annikka; Backman Janne T; Laitila Jouko; Neuvonen Pertti J; Niemi Mikko
Effect of SLCO1B1 polymorphism on the plasma concentrations of bile acids and bile acid synthesis marker in humans.
Pharmacogenetics and genomics 2009;19(6):447-57.
2009: Aitta-Aho Teemu; Vekovischeva Olga Y; Neuvonen Pertti J; Korpi Esa R
Reduced benzodiazepine tolerance, but increased flumazenil-precipitated withdrawal in AMPA-receptor GluR-A subunit-deficient mice.
Pharmacology, biochemistry, and behavior 2009;92(2):283-90.
2009: Hagelberg Nora M; Nieminen Tuija H; Saari Teijo I; Neuvonen Mikko; Neuvonen Pertti J; Laine Kari; Olkkola Klaus T
Voriconazole drastically increases exposure to oral oxycodone.
European journal of clinical pharmacology 2009;65(3):263-71.
2009: Hynninen V V; Olkkola K T; Bertilsson L; Kurkinen K J; Korhonen T; Neuvonen P J; Laine K
Voriconazole increases while itraconazole decreases plasma meloxicam concentrations.
Antimicrobial agents and chemotherapy 2009;53(2):587-92.
2008: Kalliokoski Annikka; Neuvonen Mikko; Neuvonen Pertti J; Niemi Mikko
The effect of SLCO1B1 polymorphism on repaglinide pharmacokinetics persists over a wide dose range.
British journal of clinical pharmacology 2008;66(6):818-25.
2008: Kalliokoski Annikka; Backman Janne T; Neuvonen Pertti J; Niemi Mikko
Effects of the SLCO1B1*1B haplotype on the pharmacokinetics and pharmacodynamics of repaglinide and nateglinide.
Pharmacogenetics and genomics 2008;18(11):937-42.
2008: Kalliokoski A; Backman J T; Kurkinen K J; Neuvonen P J; Niemi M
Effects of gemfibrozil and atorvastatin on the pharmacokinetics of repaglinide in relation to SLCO1B1 polymorphism.
Clinical pharmacology and therapeutics 2008;84(4):488-96.
2008: Liukas A; Kuusniemi K; Aantaa R; Virolainen P; Neuvonen M; Neuvonen P J; Olkkola K T
Plasma concentrations of oral oxycodone are greatly increased in the elderly.
Clinical pharmacology and therapeutics 2008;84(4):462-7.
2008: Pasanen Marja K; Miettinen Tatu A; Gylling Helena; Neuvonen Pertti J; Niemi Mikko
Polymorphism of the hepatic influx transporter organic anion transporting polypeptide 1B1 is associated with increased cholesterol synthesis rate.
Pharmacogenetics and genomics 2008;18(10):921-6.
2008: Ruokoniemi Päivi; Helin-Salmivaara Arja; Klaukka Timo; Neuvonen Pertti J; Huupponen Risto
Shift of statin use towards the elderly in 1995-2005: a nation-wide register study in Finland.
British journal of clinical pharmacology 2008;66(3):405-10.
2008: Tornio A; Niemi M; Neuvonen M; Laitila J; Kalliokoski A; Neuvonen P J; Backman J T
The effect of gemfibrozil on repaglinide pharmacokinetics persists for at least 12 h after the dose: evidence for mechanism-based inhibition of CYP2C8 in vivo.
Clinical pharmacology and therapeutics 2008;84(3):403-11.
2008: Karjalainen Marjo J; Neuvonen Pertti J; Backman Janne T
In vitro inhibition of CYP1A2 by model inhibitors, anti-inflammatory analgesics and female sex steroids: predictability of in vivo interactions.
Basic & clinical pharmacology & toxicology 2008;103(2):157-65.
2008: Kallio H; Niskanen M L; Havia M; Neuvonen P J; Rosenberg P H; Kentala E
I.V. ropivacaine compared with lidocaine for the treatment of tinnitus.
British journal of anaesthesia 2008;101(2):261-5.
2008: Neuvonen Mikko; Neuvonen Pertti J
Determination of oxycodone, noroxycodone, oxymorphone, and noroxymorphone in human plasma by liquid chromatography-electrospray-tandem mass spectrometry.
Therapeutic drug monitoring 2008;30(3):333-40.
2008: Karjalainen Marjo J; Neuvonen Pertti J; Backman Janne T
Celecoxib is a CYP1A2 inhibitor in vitro but not in vivo.
European journal of clinical pharmacology 2008;64(5):511-9.
2008: Kalliokoski Annikka; Neuvonen Mikko; Neuvonen Pertti J; Niemi Mikko
Different effects of SLCO1B1 polymorphism on the pharmacokinetics and pharmacodynamics of repaglinide and nateglinide.
Journal of clinical pharmacology 2008;48(3):311-21.
2008: Fanta Samuel; Niemi Mikko; Jönsson Siv; Karlsson Mats O; Holmberg Christer; Neuvonen Pertti J; Hoppu Kalle; Backman Janne T
Pharmacogenetics of cyclosporine in children suggests an age-dependent influence of ABCB1 polymorphisms.
Pharmacogenetics and genomics 2008;18(2):77-90.
2008: Hynninen V-V; Olkkola K T; Bertilsson L; Kurkinen K; Neuvonen P J; Laine K
Effect of terbinafine and voriconazole on the pharmacokinetics of the antidepressant venlafaxine.
Clinical pharmacology and therapeutics 2008;83(2):342-8.
2008: Pasanen Marja K; Neuvonen Pertti J; Niemi Mikko
Global analysis of genetic variation in SLCO1B1.
Pharmacogenomics 2008;9(1):19-33.
2008: Saari Teijo I; Laine Kari; Neuvonen Mikko; Neuvonen Pertti J; Olkkola Klaus T
Effect of voriconazole and fluconazole on the pharmacokinetics of intravenous fentanyl.
European journal of clinical pharmacology 2008;64(1):25-30.
2008: Backman Janne T; Schröder Marika T; Neuvonen Pertti J
Effects of gender and moderate smoking on the pharmacokinetics and effects of the CYP1A2 substrate tizanidine.
European journal of clinical pharmacology 2008;64(1):17-24.
2008: Tornio Aleksi; Niemi Mikko; Neuvonen Pertti J; Backman Janne T
Trimethoprim and the CYP2C8*3 allele have opposite effects on the pharmacokinetics of pioglitazone.
Drug metabolism and disposition: the biological fate of chemicals 2008;36(1):73-80.
2008: Kalliokoski Annikka; Neuvonen Mikko; Neuvonen Pertti J; Niemi Mikko
No significant effect of SLCO1B1 polymorphism on the pharmacokinetics of rosiglitazone and pioglitazone.
British journal of clinical pharmacology 2008;65(1):78-86.
2008: Helin-Salmivaara Arja; Lavikainen Piia; Korhonen Maarit J; Halava Heli; Junnila Seppo Y T; Kettunen Raimo; Neuvonen Pertti J; Martikainen Jaana E; Ruokoniemi Päivi; Saastamoinen Leena K; Virta Lauri; Huupponen Risto
Long-term persistence with statin therapy: a nationwide register study in Finland.
Clinical therapeutics 2008;30 Pt 2():2228-40.
2008: Neuvonen Pertti J; Backman Janne T; Niemi Mikko
Pharmacokinetic comparison of the potential over-the-counter statins simvastatin, lovastatin, fluvastatin and pravastatin.
Clinical pharmacokinetics 2008;47(7):463-74.
2007: Hynninen Ville-Veikko; Olkkola Klaus T; Leino Kari; Lundgren Stefan; Neuvonen Pertti J; Rane Anders; Valtonen Mika; Laine Kari
Effect of voriconazole on the pharmacokinetics of diclofenac.
Fundamental & clinical pharmacology 2007;21(6):651-6.
2007: Pasanen M K; Fredrikson H; Neuvonen P J; Niemi M
Different effects of SLCO1B1 polymorphism on the pharmacokinetics of atorvastatin and rosuvastatin.
Clinical pharmacology and therapeutics 2007;82(6):726-33.
2007: Saari Teijo I; Laine Kari; Bertilsson Leif; Neuvonen Pertti J; Olkkola Klaus T
Voriconazole and fluconazole increase the exposure to oral diazepam.
European journal of clinical pharmacology 2007;63(10):941-9.
2007: Karjalainen Marjo J; Neuvonen Pertti J; Backman Janne T
Tolfenamic acid is a potent CYP1A2 inhibitor in vitro but does not interact in vivo: correction for protein binding is needed for data interpretation.
European journal of clinical pharmacology 2007;63(9):829-36.
2007: Schneider B; Gerdsen R; Plat J; Dullens S; Björkhem I; Diczfalusy U; Neuvonen P J; Bieber T; von Bergmann K; Lütjohann D
Effects of high-dose itraconazole treatment on lipoproteins in men.
International journal of clinical pharmacology and therapeutics 2007;45(7):377-84.
2007: Seitsonen E R J; Cohen-Laroque E-S; van Gils M J; Korttila K T; Neuvonen P J; Yli-Hankala A M
Propofol versus alfentanil to prevent movement responses during uterine curettage.
Acta anaesthesiologica Scandinavica 2007;51(6):751-8.
2007: Lilja J J; Backman J T; Neuvonen P J
Effects of daily ingestion of cranberry juice on the pharmacokinetics of warfarin, tizanidine, and midazolam--probes of CYP2C9, CYP1A2, and CYP3A4.
Clinical pharmacology and therapeutics 2007;81(6):833-9.
2007: Lilja Jari J; Niemi Mikko; Fredrikson Hanna; Neuvonen Pertti J
Effects of clarithromycin and grapefruit juice on the pharmacokinetics of glibenclamide.
British journal of clinical pharmacology 2007;63(6):732-40.
2007: Tornio Aleksi; Niemi Mikko; Neuvonen Pertti J; Backman Janne T
Stereoselective interaction between the CYP2C8 inhibitor gemfibrozil and racemic ibuprofen.
European journal of clinical pharmacology 2007;63(5):463-9.
2007: Jokinen Mika J; Neuvonen Pertti J; Lindgren Leena; Höckerstedt Krister; Sjövall Jan; Breuer Olof; Askemark Yvonne; Ahonen Jouni; Olkkola Klaus T
Pharmacokinetics of ropivacaine in patients with chronic end-stage liver disease.
Anesthesiology 2007;106(1):43-55.
2007: Saari Teijo I; Laine Kari; Leino Kari; Valtonen Mika; Neuvonen Pertti J; Olkkola Klaus T
Effect of voriconazole on the pharmacokinetics and pharmacodynamics of zolpidem in healthy subjects.
British journal of clinical pharmacology 2007;63(1):116-20.
2006: Rautiainen H; Färkkilä M; Neuvonen M; Sane T; Karvonen A-L; Nurmi H; Kärkkäinen P; Neuvonen P J; Backman J T
Pharmacokinetics and bone effects of budesonide in primary biliary cirrhosis.
Alimentary pharmacology & therapeutics 2006;24(11-12):1545-52.
2006: Neuvonen Pertti J; Niemi Mikko; Backman Janne T
Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance.
Clinical pharmacology and therapeutics 2006;80(6):565-81.
2006: Pasanen Marja K; Neuvonen Mikko; Neuvonen Pertti J; Niemi Mikko
SLCO1B1 polymorphism markedly affects the pharmacokinetics of simvastatin acid.
Pharmacogenetics and genomics 2006;16(12):873-9.
2006: Karjalainen Marjo J; Neuvonen Pertti J; Backman Janne T
Rofecoxib is a potent, metabolism-dependent inhibitor of CYP1A2: implications for in vitro prediction of drug interactions.
Drug metabolism and disposition: the biological fate of chemicals 2006;34(12):2091-6.
2006: Saari Teijo I; Laine Kari; Leino Kari; Valtonen Mika; Neuvonen Pertti J; Olkkola Klaus T
Voriconazole, but not terbinafine, markedly reduces alfentanil clearance and prolongs its half-life.
Clinical pharmacology and therapeutics 2006;80(5):502-8.
2006: Niemi Mikko; Arnold Katja A; Backman Janne T; Pasanen Marja K; Gödtel-Armbrust Ute; Wojnowski Leszek; Zanger Ulrich M; Neuvonen Pertti J; Eichelbaum Michel; Kivistö Kari T; Lang Thomas
Association of genetic polymorphism in ABCC2 with hepatic multidrug resistance-associated protein 2 expression and pravastatin pharmacokinetics.
Pharmacogenetics and genomics 2006;16(11):801-8.
2006: Niemi Mikko; Pasanen Marja K; Neuvonen Pertti J
SLCO1B1 polymorphism and sex affect the pharmacokinetics of pravastatin but not fluvastatin.
Clinical pharmacology and therapeutics 2006;80(4):356-66.
2006: Backman Janne T; Karjalainen Marjo J; Neuvonen Mikko; Laitila Jouko; Neuvonen Pertti J
Rofecoxib is a potent inhibitor of cytochrome P450 1A2: studies with tizanidine and caffeine in healthy subjects.
British journal of clinical pharmacology 2006;62(3):345-57.
2006: Backman J T; Kajosaari L I; Niemi M; Neuvonen P J
Cyclosporine A increases plasma concentrations and effects of repaglinide.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2006;6(9):2221-2.
2006: Isohanni Mika H; Neuvonen Pertti J; Olkkola Klaus T
Effect of fluvoxamine and erythromycin on the pharmacokinetics of oral lidocaine.
Basic & clinical pharmacology & toxicology 2006;99(2):168-72.
2006: Tornio Aleksi; Neuvonen Pertti J; Backman Janne T
The CYP2C8 inhibitor gemfibrozil does not increase the plasma concentrations of zopiclone.
European journal of clinical pharmacology 2006;62(8):645-51.
2006: Munsterhjelm E; Niemi T T; Ylikorkala O; Neuvonen P J; Rosenberg P H
Influence on platelet aggregation of i.v. parecoxib and acetaminophen in healthy volunteers.
British journal of anaesthesia 2006;97(2):226-31.
2006: Jaakkola Tiina; Laitila Jouko; Neuvonen Pertti J; Backman Janne T
Pioglitazone is metabolised by CYP2C8 and CYP3A4 in vitro: potential for interactions with CYP2C8 inhibitors.
Basic & clinical pharmacology & toxicology 2006;99(1):44-51.
2006: Jaakkola Tiina; Backman Janne T; Neuvonen Mikko; Niemi Mikko; Neuvonen Pertti J
Montelukast and zafirlukast do not affect the pharmacokinetics of the CYP2C8 substrate pioglitazone.
European journal of clinical pharmacology 2006;62(7):503-9.
2006: Niemi Mikko; Tornio Aleksi; Pasanen Marja K; Fredrikson Hanna; Neuvonen Pertti J; Backman Janne T
Itraconazole, gemfibrozil and their combination markedly raise the plasma concentrations of loperamide.
European journal of clinical pharmacology 2006;62(6):463-72.
2006: Backman Janne T; Granfors Marika T; Neuvonen Pertti J
Rifampicin is only a weak inducer of CYP1A2-mediated presystemic and systemic metabolism: studies with tizanidine and caffeine.
European journal of clinical pharmacology 2006;62(6):451-61.
2006: Pasanen Marja K; Backman Janne T; Neuvonen Pertti J; Niemi Mikko
Frequencies of single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide 1B1 SLCO1B1 gene in a Finnish population.
European journal of clinical pharmacology 2006;62(6):409-15.
2006: Hynninen Ville-Veikko; Olkkola Klaus T; Leino Kari; Lundgren Stefan; Neuvonen Pertti J; Rane Anders; Valtonen Mika; Vyyryläinen Hanna; Laine Kari
Effects of the antifungals voriconazole and fluconazole on the pharmacokinetics of s-(+)- and R-(-)-Ibuprofen.
Antimicrobial agents and chemotherapy 2006;50(6):1967-72.
2006: Hedman Mia; Antikainen Marjatta; Holmberg Christer; Neuvonen Mikko; Eichelbaum Michel; Kivistö Kari T; Neuvonen Pertti J; Niemi Mikko
Pharmacokinetics and response to pravastatin in paediatric patients with familial hypercholesterolaemia and in paediatric cardiac transplant recipients in relation to polymorphisms of the SLCO1B1 and ABCB1 genes.
British journal of clinical pharmacology 2006;61(6):706-15.
2006: Lilja Jari J; Juntti-Patinen Laura; Neuvonen Pertti J
Effect of rifampicin on the pharmacokinetics of atenolol.
Basic & clinical pharmacology & toxicology 2006;98(6):555-8.
2006: Niemi T T; Neuvonen P J; Rosenberg P H
Comparison of ropivacaine 2 mg ml(-1) and prilocaine 5 mg ml(-1) for i.v. regional anaesthesia in outpatient surgery.
British journal of anaesthesia 2006;96(5):640-4.
2006: Saari Teijo I; Laine Kari; Leino Kari; Valtonen Mika; Neuvonen Pertti J; Olkkola Klaus T
Effect of voriconazole on the pharmacokinetics and pharmacodynamics of intravenous and oral midazolam.
Clinical pharmacology and therapeutics 2006;79(4):362-70.
2006: Kajosaari Lauri I; Niemi Mikko; Backman Janne T; Neuvonen Pertti J
Telithromycin, but not montelukast, increases the plasma concentrations and effects of the cytochrome P450 3A4 and 2C8 substrate repaglinide.
Clinical pharmacology and therapeutics 2006;79(3):231-42.
2006: Kajosaari Lauri I; Jaakkola Tiina; Neuvonen Pertti J; Backman Janne T
Pioglitazone, an in vitro inhibitor of CYP2C8 and CYP3A4, does not increase the plasma concentrations of the CYP2C8 and CYP3A4 substrate repaglinide.
European journal of clinical pharmacology 2006;62(3):217-23.
2006: Juntti-Patinen Laura; Kuitunen Tapio; Pere Pertti; Neuvonen Pertti J
Drug-related visits to a district hospital emergency room.
Basic & clinical pharmacology & toxicology 2006;98(2):212-7.
2006: Granfors Marika T; Wang Jun-Sheng; Kajosaari Lauri I; Laitila Jouko; Neuvonen Pertti J; Backman Janne T
Differential inhibition of cytochrome P450 3A4, 3A5 and 3A7 by five human immunodeficiency virus (HIV) protease inhibitors in vitro.
Basic & clinical pharmacology & toxicology 2006;98(1):79-85.
2006: Jaakkola Tiina; Backman Janne T; Neuvonen Mikko; Laitila Jouko; Neuvonen Pertti J
Effect of rifampicin on the pharmacokinetics of pioglitazone.
British journal of clinical pharmacology 2006;61(1):70-8.
2005: Lilja Jari J; Backman Janne T; Neuvonen Pertti J
Effect of itraconazole on the pharmacokinetics of atenolol.
Basic & clinical pharmacology & toxicology 2005;97(6):395-8.
2005: Malm Heli; Klaukka Timo; Neuvonen Pertti J
Risks associated with selective serotonin reuptake inhibitors in pregnancy.
Obstetrics and gynecology 2005;106(6):1289-96.
2005: Lilja Jari J; Raaska Kari; Neuvonen Pertti J
Effects of grapefruit juice on the pharmacokinetics of acebutolol.
British journal of clinical pharmacology 2005;60(6):659-63.
2005: Granfors Marika T; Backman Janne T; Laitila Jouko; Neuvonen Pertti J
Oral contraceptives containing ethinyl estradiol and gestodene markedly increase plasma concentrations and effects of tizanidine by inhibiting cytochrome P450 1A2.
Clinical pharmacology and therapeutics 2005;78(4):400-11.
2005: Kajosaari Lauri I; Niemi Mikko; Neuvonen Mikko; Laitila Jouko; Neuvonen Pertti J; Backman Janne T
Cyclosporine markedly raises the plasma concentrations of repaglinide.
Clinical pharmacology and therapeutics 2005;78(4):388-99.
2005: Munsterhjelm Edward; Munsterhjelm Nina M; Niemi Tomi T; Ylikorkala Olavi; Neuvonen Pertti J; Rosenberg Per H
Dose-dependent inhibition of platelet function by acetaminophen in healthy volunteers.
Anesthesiology 2005;103(4):712-7.
2005: Kajosaari Lauri I; Laitila Jouko; Neuvonen Pertti J; Backman Janne T
Metabolism of repaglinide by CYP2C8 and CYP3A4 in vitro: effect of fibrates and rifampicin.
Basic & clinical pharmacology & toxicology 2005;97(4):249-56.
2005: Lilja Jari J; Laitinen Kalevi; Neuvonen Pertti J
Effects of grapefruit juice on the absorption of levothyroxine.
British journal of clinical pharmacology 2005;60(3):337-41.
2005: Backman Janne T; Luurila Harri; Neuvonen Mikko; Neuvonen Pertti J
Rifampin markedly decreases and gemfibrozil increases the plasma concentrations of atorvastatin and its metabolites.
Clinical pharmacology and therapeutics 2005;78(2):154-67.
2005: Niemi Mikko; Backman Janne T; Juntti-Patinen Laura; Neuvonen Mikko; Neuvonen Pertti J
Coadministration of gemfibrozil and itraconazole has only a minor effect on the pharmacokinetics of the CYP2C9 and CYP3A4 substrate nateglinide.
British journal of clinical pharmacology 2005;60(2):208-17.
2005: Tornio Aleksi; Pasanen Marja K; Laitila Jouko; Neuvonen Pertti J; Backman Janne T
Comparison of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) as inhibitors of cytochrome P450 2C8.
Basic & clinical pharmacology & toxicology 2005;97(2):104-8.
2005: Lilja J J; Raaska K; Neuvonen P J
Effects of orange juice on the pharmacokinetics of atenolol.
European journal of clinical pharmacology 2005;61(5-6):337-40.
2005: Niemi Mikko; Backman Janne T; Kajosaari Lauri I; Leathart Julian B; Neuvonen Mikko; Daly Ann K; Eichelbaum Michel; Kivistö Kari T; Neuvonen Pertti J
Polymorphic organic anion transporting polypeptide 1B1 is a major determinant of repaglinide pharmacokinetics.
Clinical pharmacology and therapeutics 2005;77(6):468-78.
2005: Jaakkola Tiina; Backman Janne T; Neuvonen Mikko; Neuvonen Pertti J
Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics of pioglitazone.
Clinical pharmacology and therapeutics 2005;77(5):404-14.
2005: Niemi Mikko; Neuvonen Pertti J; Hofmann Ute; Backman Janne T; Schwab Matthias; Lütjohann Dieter; von Bergmann Klaus; Eichelbaum Michel; Kivistö Kari T
Acute effects of pravastatin on cholesterol synthesis are associated with SLCO1B1 (encoding OATP1B1) haplotype *17.
Pharmacogenetics and genomics 2005;15(5):303-9.
2005: Olkkola Klaus T; Isohanni Mika H; Hamunen Katri; Neuvonen Pertti J
The effect of erythromycin and fluvoxamine on the pharmacokinetics of intravenous lidocaine.
Anesthesia and analgesia 2005;100(5):1352-6, table of contents.
2005: Lilja Jari J; Backman Janne T; Neuvonen Pertti J
Effect of gemfibrozil on the pharmacokinetics and pharmacodynamics of racemic warfarin in healthy subjects.
British journal of clinical pharmacology 2005;59(4):433-9.
2005: Alaspää Ari O; Kuisma Markku J; Hoppu Kalle; Neuvonen Pertti J
Out-of-hospital administration of activated charcoal by emergency medical services.
Annals of emergency medicine 2005;45(2):207-12.
2004: Granfors Marika T; Backman Janne T; Neuvonen Mikko; Neuvonen Pertti J
Ciprofloxacin greatly increases concentrations and hypotensive effect of tizanidine by inhibiting its cytochrome P450 1A2-mediated presystemic metabolism.
Clinical pharmacology and therapeutics 2004;76(6):598-606.
2004: Kajosaari Lauri I; Backman Janne T; Neuvonen Mikko; Laitila Jouko; Neuvonen Pertti J
Lack of effect of bezafibrate and fenofibrate on the pharmacokinetics and pharmacodynamics of repaglinide.
British journal of clinical pharmacology 2004;58(4):390-6.
2004: Isohanni Mika H; Neuvonen Pertti J; Olkkola Klaus T
Effect of itraconazole on the pharmacokinetics of inhaled lidocaine.
Basic & clinical pharmacology & toxicology 2004;95(3):120-3.
2004: Niemi Mikko; Backman Janne T; Neuvonen Pertti J
Effects of trimethoprim and rifampin on the pharmacokinetics of the cytochrome P450 2C8 substrate rosiglitazone.
Clinical pharmacology and therapeutics 2004;76(3):239-49.
2004: Niemi Mikko; Schaeffeler Elke; Lang Thomas; Fromm Martin F; Neuvonen Mikko; Kyrklund Carl; Backman Janne T; Kerb Reinhold; Schwab Matthias; Neuvonen Pertti J; Eichelbaum Michel; Kivistö Kari T
High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1).
Pharmacogenetics 2004;14(7):429-40.
2004: Lilja Jari J; Neuvonen Mikko; Neuvonen Pertti J
Effects of regular consumption of grapefruit juice on the pharmacokinetics of simvastatin.
British journal of clinical pharmacology 2004;58(1):56-60.
2004: Granfors Marika T; Backman Janne T; Neuvonen Mikko; Ahonen Jouni; Neuvonen Pertti J
Fluvoxamine drastically increases concentrations and effects of tizanidine: a potentially hazardous interaction.
Clinical pharmacology and therapeutics 2004;75(4):331-41.
2004: Niemi Mikko; Kajosaari Lauri I; Neuvonen Mikko; Backman Janne T; Neuvonen Pertti J
The CYP2C8 inhibitor trimethoprim increases the plasma concentrations of repaglinide in healthy subjects.
British journal of clinical pharmacology 2004;57(4):441-7.
2004: Lilja Jari J; Juntti-Patinen Laura; Neuvonen Pertti J
Orange juice substantially reduces the bioavailability of the beta-adrenergic-blocking agent celiprolol.
Clinical pharmacology and therapeutics 2004;75(3):184-90.
2004: Granfors Marika T; Backman Janne T; Laitila Jouko; Neuvonen Pertti J
Tizanidine is mainly metabolized by cytochrome p450 1A2 in vitro.
British journal of clinical pharmacology 2004;57(3):349-53.
2004: Kyrklund Carl; Backman Janne T; Neuvonen Mikko; Neuvonen Pertti J
Effect of rifampicin on pravastatin pharmacokinetics in healthy subjects.
British journal of clinical pharmacology 2004;57(2):181-7.
2004: Ucar M; Neuvonen M; Luurila H; Dahlqvist R; Neuvonen P J; Mjörndal T
Carbamazepine markedly reduces serum concentrations of simvastatin and simvastatin acid.
European journal of clinical pharmacology 2004;59(12):879-82.
2004: Hedman Mia; Neuvonen Pertti J; Neuvonen Mikko; Holmberg Christer; Antikainen Marjatta
Pharmacokinetics and pharmacodynamics of pravastatin in pediatric and adolescent cardiac transplant recipients on a regimen of triple immunosuppression.
Clinical pharmacology and therapeutics 2004;75(1):101-9.
2004: Raaska Kari; Raitasuo Virpi; Laitila Jouko; Neuvonen Pertti J
Effect of caffeine-containing versus decaffeinated coffee on serum clozapine concentrations in hospitalised patients.
Basic & clinical pharmacology & toxicology 2004;94(1):13-8.
2004: Mäenpää Jukka; Tarpila Anneli; Jouhikainen Taneli; Ikävalko Harri; Löyttyniemi Eliisa; Perttunen Kristiina; Neuvonen Pertti J; Tarpila Simo
Magnesium hydroxide in ibuprofen tablet reduces the gastric mucosal tolerability of ibuprofen.
Journal of clinical gastroenterology 2004;38(1):41-5.
2004: Lilja J J; Niemi M; Neuvonen P J
Rifampicin reduces plasma concentrations of celiprolol.
European journal of clinical pharmacology 2004;59(11):819-24.
2004: Malm Heli; Martikainen Jaana; Klaukka Timo; Neuvonen Pertti J
Prescription of hazardous drugs during pregnancy.
Drug safety : an international journal of medical toxicology and drug experience 2004;27(12):899-908.
2003: Niemi Mikko; Leathart Julian B; Neuvonen Mikko; Backman Janne T; Daly Ann K; Neuvonen Pertti J
Polymorphism in CYP2C8 is associated with reduced plasma concentrations of repaglinide.
Clinical pharmacology and therapeutics 2003;74(4):380-7.
2003: Förster J G; Niemi T T; Aromaa U; Neuvonen P J; Seppälä T A; Rosenberg P H
Epinephrine added to a lumbar epidural infusion of a small-dose ropivacaine-fentanyl mixture after arterial bypass surgery of the lower extremities.
Acta anaesthesiologica Scandinavica 2003;47(9):1106-13.
2003: Niemi Mikko; Backman Janne T; Neuvonen Mikko; Neuvonen Pertti J
Effect of rifampicin on the pharmacokinetics and pharmacodynamics of nateglinide in healthy subjects.
British journal of clinical pharmacology 2003;56(4):427-32.
2003: Niemi M; Backman J T; Granfors M; Laitila J; Neuvonen M; Neuvonen P J
Gemfibrozil considerably increases the plasma concentrations of rosiglitazone.
Diabetologia 2003;46(10):1319-23.
2003: Hedman Mia; Neuvonen Pertti J; Neuvonen Mikko; Antikainen Marjatta
Pharmacokinetics and pharmacodynamics of pravastatin in children with familial hypercholesterolemia.
Clinical pharmacology and therapeutics 2003;74(2):178-85.
2003: Niemi Mikko; Neuvonen Mikko; Juntti-Patinen Laura; Backman Janne T; Neuvonen Pertti J
Effect of fluconazole on the pharmacokinetics and pharmacodynamics of nateglinide.
Clinical pharmacology and therapeutics 2003;74(1):25-31.
2003: Kyrklund Carl; Backman Janne T; Neuvonen Mikko; Neuvonen Pertti J
Gemfibrozil increases plasma pravastatin concentrations and reduces pravastatin renal clearance.
Clinical pharmacology and therapeutics 2003;73(6):538-44.
2003: Malm Heli; Martikainen Jaana; Klaukka Timo; Neuvonen Pertti J;
Prescription drugs during pregnancy and lactation--a Finnish register-based study.
European journal of clinical pharmacology 2003;59(2):127-33.
2003: Niemi M; Backman J T; Neuvonen M; Neuvonen P J
Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics and pharmacodynamics of repaglinide: potentially hazardous interaction between gemfibrozil and repaglinide.
Diabetologia 2003;46(3):347-51.
2003: Lilja Jari J; Backman Janne T; Laitila Jouko; Luurila Harri; Neuvonen Pertti J
Itraconazole increases but grapefruit juice greatly decreases plasma concentrations of celiprolol.
Clinical pharmacology and therapeutics 2003;73(3):192-8.
2003: Jokinen Mika J; Olkkola Klaus T; Ahonen Jouni; Neuvonen Pertti J
Effect of ciprofloxacin on the pharmacokinetics of ropivacaine.
European journal of clinical pharmacology 2003;58(10):653-7.
2003: Pere Pertti; Salonen Merja; Jokinen Mika; Rosenberg Per H; Neuvonen Pertti J; Haasio Juhani
Pharmacokinetics of ropivacaine in uremic and nonuremic patients after axillary brachial plexus block.
Anesthesia and analgesia 2003;96(2):563-9, table of contents.
2003: Niemi Mikko; Backman Janne T; Fromm Martin F; Neuvonen Pertti J; Kivistö Kari T
Pharmacokinetic interactions with rifampicin : clinical relevance.
Clinical pharmacokinetics 2003;42(9):819-50.
2002: Backman Janne T; Kyrklund Carl; Neuvonen Mikko; Neuvonen Pertti J
Gemfibrozil greatly increases plasma concentrations of cerivastatin.
Clinical pharmacology and therapeutics 2002;72(6):685-91.
2002: Raaska K; Raitasuo V; Neuvonen P J
Therapeutic drug monitoring data: risperidone does not increase serum clozapine concentration.
European journal of clinical pharmacology 2002;58(9):587-91.
2002: Wang Jun-Sheng; Neuvonen Mikko; Wen Xia; Backman Janne T; Neuvonen Pertti J
Gemfibrozil inhibits CYP2C8-mediated cerivastatin metabolism in human liver microsomes.
Drug metabolism and disposition: the biological fate of chemicals 2002;30(12):1352-6.
2002: Juntti-Patinen L; Neuvonen P J
Drug-related deaths in a university central hospital.
European journal of clinical pharmacology 2002;58(7):479-82.
2002: Raaska Kari; Niemi Mikko; Neuvonen Mikko; Neuvonen Pertti J; Kivistö Kari T
Plasma concentrations of inhaled budesonide and its effects on plasma cortisol are increased by the cytochrome P4503A4 inhibitor itraconazole.
Clinical pharmacology and therapeutics 2002;72(4):362-9.
2002: Niemi Mikko; Cascorbi Ingolf; Timm Ramona; Kroemer Heyo K; Neuvonen Pertti J; Kivistö Kari T
Glyburide and glimepiride pharmacokinetics in subjects with different CYP2C9 genotypes.
Clinical pharmacology and therapeutics 2002;72(3):326-32.
2002: Raaska K; Raitasuo V; Arstila M; Neuvonen P J
Bacterial pneumonia can increase serum concentration of clozapine.
European journal of clinical pharmacology 2002;58(5):321-2.
2002: Wang Jun-Sheng; Wen Xia; Backman Janne T; Neuvonen Pertti J
Effect of albumin and cytosol on enzyme kinetics of tolbutamide hydroxylation and on inhibition of CYP2C9 by gemfibrozil in human liver microsomes.
The Journal of pharmacology and experimental therapeutics 2002;302(1):43-9.
2002: Wen Xia; Wang Jun-Sheng; Backman Janne T; Laitila Jouko; Neuvonen Pertti J
Trimethoprim and sulfamethoxazole are selective inhibitors of CYP2C8 and CYP2C9, respectively.
Drug metabolism and disposition: the biological fate of chemicals 2002;30(6):631-5.
2002: Lamminpää Anne; Pukkala Eero; Teppo Lyly; Neuvonen Pertti J
Cancer incidence among patients using antiepileptic drugs: a long-term follow-up of 28,000 patients.
European journal of clinical pharmacology 2002;58(2):137-41.
2002: Wen Xia; Wang Jun-Sheng; Neuvonen Pertti J; Backman Janne T
Isoniazid is a mechanism-based inhibitor of cytochrome P450 1A2, 2A6, 2C19 and 3A4 isoforms in human liver microsomes.
European journal of clinical pharmacology 2002;57(11):799-804.
2001: Raaska K; Raitasuo V; Neuvonen P J
Effect of influenza vaccination on serum clozapine and its main metabolite concentrations in patients with schizophrenia.
European journal of clinical pharmacology 2001;57(10):705-8.
2001: Valtonen M; Tiula E; Takkunen O; Backman J T; Neuvonen P J
Elimination of the piperacillin/tazobactam combination during continuous venovenous haemofiltration and haemodiafiltration in patients with acute renal failure.
The Journal of antimicrobial chemotherapy 2001;48(6):881-5.
2001: Wen X; Wang J S; Kivistö K T; Neuvonen P J; Backman J T
In vitro evaluation of valproic acid as an inhibitor of human cytochrome P450 isoforms: preferential inhibition of cytochrome P450 2C9 (CYP2C9).
British journal of clinical pharmacology 2001;52(5):547-53.
2001: Niemi M; Neuvonen P J; Kivistö K T
Effect of gemfibrozil on the pharmacokinetics and pharmacodynamics of glimepiride.
Clinical pharmacology and therapeutics 2001;70(5):439-45.
2001: Wen X; Wang J S; Backman J T; Kivistö K T; Neuvonen P J
Gemfibrozil is a potent inhibitor of human cytochrome P450 2C9.
Drug metabolism and disposition: the biological fate of chemicals 2001;29(11):1359-61.
2001: Jokinen M J; Olkkola K T; Ahonen J; Neuvonen P J
Effect of rifampin and tobacco smoking on the pharmacokinetics of ropivacaine.
Clinical pharmacology and therapeutics 2001;70(4):344-50.
2001: Villikka K; Varis T; Backman J T; Neuvonen P J; Kivistö K T
Effect of methylprednisolone on CYP3A4-mediated drug metabolism in vivo.
European journal of clinical pharmacology 2001;57(6-7):457-60.
2001: Lapatto-Reiniluoto O; Kivistö K T; Neuvonen P J
Activated charcoal alone and followed by whole-bowel irrigation in preventing the absorption of sustained-release drugs.
Clinical pharmacology and therapeutics 2001;70(3):255-60.
2001: Niemi M; Neuvonen P J; Kivistö K T
The cytochrome P4503A4 inhibitor clarithromycin increases the plasma concentrations and effects of repaglinide.
Clinical pharmacology and therapeutics 2001;70(1):58-65.
2001: Saarenmaa E; Neuvonen P J; Huttunen P; Fellman V
Ketamine for procedural pain relief in newborn infants.
Archives of disease in childhood. Fetal and neonatal edition 2001;85(1):F53-6.
2001: Niemi M; Backman J T; Neuvonen M; Neuvonen P J; Kivistö K T
Effects of rifampin on the pharmacokinetics and pharmacodynamics of glyburide and glipizide.
Clinical pharmacology and therapeutics 2001;69(6):400-6.
2001: Kyrklund C; Backman J T; Kivistö K T; Neuvonen M; Laitila J; Neuvonen P J
Plasma concentrations of active lovastatin acid are markedly increased by gemfibrozil but not by bezafibrate.
Clinical pharmacology and therapeutics 2001;69(5):340-5.
2001: Kivistö K T; Wang J S; Backman J T; Nyman L; Taavitsainen P; Anttila M; Neuvonen P J
Selegiline pharmacokinetics are unaffected by the CYP3A4 inhibitor itraconazole.
European journal of clinical pharmacology 2001;57(1):37-42.
2001: Jokinen M J; Ahonen J; Neuvonen P J; Olkkola K T
Effect of clarithromycin and itraconazole on the pharmacokinetics of ropivacaine.
Pharmacology & toxicology 2001;88(4):187-91.
2001: Niemi M; Backman J T; Neuvonen M; Laitila J; Neuvonen P J; Kivistö K T
Effects of fluconazole and fluvoxamine on the pharmacokinetics and pharmacodynamics of glimepiride.
Clinical pharmacology and therapeutics 2001;69(4):194-200.
2000: Kyrklund C; Backman J T; Kivistö K T; Neuvonen M; Laitila J; Neuvonen P J
Rifampin greatly reduces plasma simvastatin and simvastatin acid concentrations.
Clinical pharmacology and therapeutics 2000;68(6):592-7.
2000: Niemi M; Kivistö K T; Backman J T; Neuvonen P J
Effect of rifampicin on the pharmacokinetics and pharmacodynamics of glimepiride.
British journal of clinical pharmacology 2000;50(6):591-5.
2000: Pohjola-Sintonen S; Kivistö K T; Vuori E; Lapatto-Reiniluoto O; Tiula E; Neuvonen P J
Identification of drugs ingested in acute poisoning: correlation of patient history with drug analyses.
Therapeutic drug monitoring 2000;22(6):749-52.
2000: Raaska K; Neuvonen P J
Ciprofloxacin increases serum clozapine and N-desmethylclozapine: a study in patients with schizophrenia.
European journal of clinical pharmacology 2000;56(8):585-9.
2000: Wang J S; Backman J T; Kivistö K T; Neuvonen P J
Effects of metronidazole on midazolam metabolism in vitro and in vivo.
European journal of clinical pharmacology 2000;56(8):555-9.
2000: Niemi M; Backman J T; Neuvonen M; Neuvonen P J; Kivistö K T
Rifampin decreases the plasma concentrations and effects of repaglinide.
Clinical pharmacology and therapeutics 2000;68(5):495-500.
2000: Varis T; Kivistö K T; Backman J T; Neuvonen P J
The cytochrome P450 3A4 inhibitor itraconazole markedly increases the plasma concentrations of dexamethasone and enhances its adrenal-suppressant effect.
Clinical pharmacology and therapeutics 2000;68(5):487-94.
2000: Jokinen M J; Ahonen J; Neuvonen P J; Olkkola K T
The effect of erythromycin, fluvoxamine, and their combination on the pharmacokinetics of ropivacaine.
Anesthesia and analgesia 2000;91(5):1207-12.
2000: Lilja J J; Kivistö K T; Neuvonen P J
Duration of effect of grapefruit juice on the pharmacokinetics of the CYP3A4 substrate simvastatin.
Clinical pharmacology and therapeutics 2000;68(4):384-90.
2000: Palovaara S; Kivistö K T; Tapanainen P; Manninen P; Neuvonen P J; Laine K
Effect of an oral contraceptive preparation containing ethinylestradiol and gestodene on CYP3A4 activity as measured by midazolam 1'-hydroxylation.
British journal of clinical pharmacology 2000;50(4):333-7.
2000: Varis T; Kivistö K T; Neuvonen P J
Grapefruit juice can increase the plasma concentrations of oral methylprednisolone.
European journal of clinical pharmacology 2000;56(6-7):489-93.
2000: Lilja J J; Kivistö K T; Backman J T; Neuvonen P J
Effect of grapefruit juice dose on grapefruit juice-triazolam interaction: repeated consumption prolongs triazolam half-life.
European journal of clinical pharmacology 2000;56(5):411-5.
2000: Saarenmaa E; Neuvonen P J; Rosenberg P; Fellman V
Morphine clearance and effects in newborn infants in relation to gestational age.
Clinical pharmacology and therapeutics 2000;68(2):160-6.
2000: Backman J T; Kyrklund C; Kivistö K T; Wang J S; Neuvonen P J
Plasma concentrations of active simvastatin acid are increased by gemfibrozil.
Clinical pharmacology and therapeutics 2000;68(2):122-9.
2000: Wang J S; Backman J T; Taavitsainen P; Neuvonen P J; Kivistö K T
Involvement of CYP1A2 and CYP3A4 in lidocaine N-deethylation and 3-hydroxylation in humans.
Drug metabolism and disposition: the biological fate of chemicals 2000;28(8):959-65.
2000: Lapatto-Reiniluoto O; Kivistö K T; Neuvonen P J
Efficacy of activated charcoal versus gastric lavage half an hour after ingestion of moclobemide, temazepam, and verapamil.
European journal of clinical pharmacology 2000;56(4):285-8.
2000: Kantola T; Backman J T; Niemi M; Kivistö K T; Neuvonen P J
Effect of fluconazole on plasma fluvastatin and pravastatin concentrations.
European journal of clinical pharmacology 2000;56(3):225-9.
2000: Heikkinen T; Laine K; Neuvonen P J; Ekblad U
The transplacental transfer of the macrolide antibiotics erythromycin, roxithromycin and azithromycin.
BJOG : an international journal of obstetrics and gynaecology 2000;107(6):770-5.
2000: Saarenmaa E; Neuvonen P J; Fellman V
Gestational age and birth weight effects on plasma clearance of fentanyl in newborn infants.
The Journal of pediatrics 2000;136(6):767-70.
2000: Valtonen M; Tiula E; Backman J T; Neuvonen P J
Elimination of meropenem during continuous veno-venous haemofiltration and haemodiafiltration in patients with acute renal failure.
The Journal of antimicrobial chemotherapy 2000;45(5):701-4.
2000: Varis T; Kivistö K T; Neuvonen P J
The effect of itraconazole on the pharmacokinetics and pharmacodynamics of oral prednisolone.
European journal of clinical pharmacology 2000;56(1):57-60.
2000: Backman J T; Mäenpää J; Belle D J; Wrighton S A; Kivistö K T; Neuvonen P J
Lack of correlation between in vitro and in vivo studies on the effects of tangeretin and tangerine juice on midazolam hydroxylation.
Clinical pharmacology and therapeutics 2000;67(4):382-90.
2000: Varis T; Backman J T; Kivistö K T; Neuvonen P J
Diltiazem and mibefradil increase the plasma concentrations and greatly enhance the adrenal-suppressant effect of oral methylprednisolone.
Clinical pharmacology and therapeutics 2000;67(3):215-21.
2000: Lapatto-Reiniluoto O; Kivistö K T; Neuvonen P J
Gastric decontamination performed 5 min after the ingestion of temazepam, verapamil and moclobemide: charcoal is superior to lavage.
British journal of clinical pharmacology 2000;49(3):274-8.
1999: Villikka K; Kivistö K T; Mäenpää H; Joensuu H; Neuvonen P J
Cytochrome P450-inducing antiepileptics increase the clearance of vincristine in patients with brain tumors.
Clinical pharmacology and therapeutics 1999;66(6):589-93.
1999: Wang J S; Backman J T; Wen X; Taavitsainen P; Neuvonen P J; Kivistö K T
Fluvoxamine is a more potent inhibitor of lidocaine metabolism than ketoconazole and erythromycin in vitro.
Pharmacology & toxicology 1999;85(5):201-5.
1999: Kivistö K T; Lilja J J; Backman J T; Neuvonen P J
Repeated consumption of grapefruit juice considerably increases plasma concentrations of cisapride.
Clinical pharmacology and therapeutics 1999;66(5):448-53.
1999: Palkama V J; Neuvonen P J; Olkkola K T
Effect of itraconazole on the pharmacokinetics of bupivacaine enantiomers in healthy volunteers.
British journal of anaesthesia 1999;83(4):659-61.
1999: Wang J S; Wen X; Backman J T; Taavitsainen P; Neuvonen P J; Kivistö K T
Midazolam alpha-hydroxylation by human liver microsomes in vitro: inhibition by calcium channel blockers, itraconazole and ketoconazole.
Pharmacology & toxicology 1999;85(4):157-61.
1999: Backman J T; Wang J S; Wen X; Kivistö K T; Neuvonen P J
Mibefradil but not isradipine substantially elevates the plasma concentrations of the CYP3A4 substrate triazolam.
Clinical pharmacology and therapeutics 1999;66(4):401-7.
1999: Olkkola K T; Palkama V J; Neuvonen P J
Ritonavir's role in reducing fentanyl clearance and prolonging its half-life.
Anesthesiology 1999;91(3):681-5.
1999: Lilja J J; Kivistö K T; Neuvonen P J
Grapefruit juice increases serum concentrations of atorvastatin and has no effect on pravastatin.
Clinical pharmacology and therapeutics 1999;66(2):118-27.
1999: Lapatto-Reiniluoto O; Kivistö K T; Neuvonen P J
Effect of activated charcoal alone or given after gastric lavage in reducing the absorption of diazepam, ibuprofen and citalopram.
British journal of clinical pharmacology 1999;48(2):148-53.
1999: Palkama V J; Ahonen J; Neuvonen P J; Olkkola K T
Effect of saquinavir on the pharmacokinetics and pharmacodynamics of oral and intravenous midazolam.
Clinical pharmacology and therapeutics 1999;66(1):33-9.
1999: Varis T; Kivistö K T; Backman J T; Neuvonen P J
Itraconazole decreases the clearance and enhances the effects of intravenously administered methylprednisolone in healthy volunteers.
Pharmacology & toxicology 1999;85(1):29-32.
1999: Kivistö K T; Laitila J; Mårtensson K; Neuvonen P J
Determination of buspirone and 1-(2-pyrimidinyl)-piperazine (1-PP) in human plasma by capillary gas chromatography.
Therapeutic drug monitoring 1999;21(3):317-21.
1999: Ahonen J; Olkkola K T; Takala A; Neuvonen P J
Interaction between fluconazole and midazolam in intensive care patients.
Acta anaesthesiologica Scandinavica 1999;43(5):509-14.
1999: Lamberg T S; Kivistö K T; Neuvonen P J
Lack of effect of terfenadine on the pharmacokinetics of the CYP3A4 substrate buspirone.
Pharmacology & toxicology 1999;84(4):165-9.
1999: Villikka K; Kivistö K T; Neuvonen P J
The effect of rifampin on the pharmacokinetics of oral and intravenous ondansetron.
Clinical pharmacology and therapeutics 1999;65(4):377-81.
1999: Isohanni M H; Neuvonen P J; Olkkola K T
Effect of erythromycin and itraconazole on the pharmacokinetics of oral lignocaine.
Pharmacology & toxicology 1999;84(3):143-6.
1999: Kivistö K T; Lamberg T S; Neuvonen P J
Interactions of buspirone with itraconazole and rifampicin: effects on the pharmacokinetics of the active 1-(2-pyrimidinyl)-piperazine metabolite of buspirone.
Pharmacology & toxicology 1999;84(2):94-7.
1999: Kantola T; Kivistö K T; Neuvonen P J
Effect of itraconazole on cerivastatin pharmacokinetics.
European journal of clinical pharmacology 1999;54(11):851-5.
1998: Lilja J J; Kivistö K T; Backman J T; Lamberg T S; Neuvonen P J
Grapefruit juice substantially increases plasma concentrations of buspirone.
Clinical pharmacology and therapeutics 1998;64(6):655-60.
1998: Kivistö K T; Villikka K; Nyman L; Anttila M; Neuvonen P J
Tamoxifen and toremifene concentrations in plasma are greatly decreased by rifampin.
Clinical pharmacology and therapeutics 1998;64(6):648-54.
1998: Lamberg T S; Kivistö K T; Laitila J; Mårtensson K; Neuvonen P J
The effect of fluvoxamine on the pharmacokinetics and pharmacodynamics of buspirone.
European journal of clinical pharmacology 1998;54(9-10):761-6.
1998: Lilja J J; Kivistö K T; Neuvonen P J
Grapefruit juice-simvastatin interaction: effect on serum concentrations of simvastatin, simvastatin acid, and HMG-CoA reductase inhibitors.
Clinical pharmacology and therapeutics 1998;64(5):477-83.
1998: Palkama V J; Neuvonen P J; Olkkola K T
The CYP 3A4 inhibitor itraconazole has no effect on the pharmacokinetics of i.v. fentanyl.
British journal of anaesthesia 1998;81(4):598-600.
1998: Varis T; Kaukonen K M; Kivistö K T; Neuvonen P J
Plasma concentrations and effects of oral methylprednisolone are considerably increased by itraconazole.
Clinical pharmacology and therapeutics 1998;64(4):363-8.
1998: Isohanni M H; Neuvonen P J; Palkama V J; Olkkola K T
Effect of erythromycin and itraconazole on the pharmacokinetics of intravenous lignocaine.
European journal of clinical pharmacology 1998;54(7):561-5.
1998: Villikka K; Kivistö K T; Neuvonen P J
The effect of dexamethasone on the pharmacokinetics of triazolam.
Pharmacology & toxicology 1998;83(3):135-8.
1998: Kantola T; Kivistö K T; Neuvonen P J
Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations.
Clinical pharmacology and therapeutics 1998;64(2):177-82.
1998: Kantola T; Kivistö K T; Neuvonen P J
Effect of itraconazole on the pharmacokinetics of atorvastatin.
Clinical pharmacology and therapeutics 1998;64(1):58-65.
1998: Kivistö K T; Kantola T; Neuvonen P J
Different effects of itraconazole on the pharmacokinetics of fluvastatin and lovastatin.
British journal of clinical pharmacology 1998;46(1):49-53.
1998: Palkama V J; Isohanni M H; Neuvonen P J; Olkkola K T
The effect of intravenous and oral fluconazole on the pharmacokinetics and pharmacodynamics of intravenous alfentanil.
Anesthesia and analgesia 1998;87(1):190-4.
1998: Lapatto-Reiniluoto O; Kivistö K T; Pohjola-Sintonen S; Luomanmäki K; Neuvonen P J
A prospective study of acute poisonings in Finnish hospital patients.
Human & experimental toxicology 1998;17(6):307-11.
1998: Lamberg T S; Kivistö K T; Neuvonen P J
Effects of verapamil and diltiazem on the pharmacokinetics and pharmacodynamics of buspirone.
Clinical pharmacology and therapeutics 1998;63(6):640-5.
1998: Luurila H; Kivistö K T; Neuvonen P J
Effect of itraconazole on the pharmacokinetics and pharmacodynamics of zolpidem.
European journal of clinical pharmacology 1998;54(2):163-6.
1998: Kantola T; Kivistö K T; Neuvonen P J
Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin acid.
Clinical pharmacology and therapeutics 1998;63(4):397-402.
1998: Lamberg T S; Kivistö K T; Neuvonen P J
Concentrations and effects of buspirone are considerably reduced by rifampicin.
British journal of clinical pharmacology 1998;45(4):381-5.
1998: Backman J T; Kivistö K T; Olkkola K T; Neuvonen P J
The area under the plasma concentration-time curve for oral midazolam is 400-fold larger during treatment with itraconazole than with rifampicin.
European journal of clinical pharmacology 1998;54(1):53-8.
1998: Neuvonen P J; Kantola T; Kivistö K T
Simvastatin but not pravastatin is very susceptible to interaction with the CYP3A4 inhibitor itraconazole.
Clinical pharmacology and therapeutics 1998;63(3):332-41.
1998: Kaukonen K M; Olkkola K T; Neuvonen P J
Fluconazole but not itraconazole decreases the metabolism of losartan to E-3174.
European journal of clinical pharmacology 1998;53(6):445-9.
1998: Lukkari E; Hakonen T; Neuvonen P J
The pharmacokinetics of oxybutynin is unaffected by gender and contraceptive steroids.
European journal of clinical pharmacology 1998;53(5):351-4.
1997: Villikka K; Kivistö K T; Luurila H; Neuvonen P J
Rifampin reduces plasma concentrations and effects of zolpidem.
Clinical pharmacology and therapeutics 1997;62(6):629-34.
1997: Jalava K M; Partanen J; Neuvonen P J
Itraconazole decreases renal clearance of digoxin.
Therapeutic drug monitoring 1997;19(6):609-13.
1997: Valtonen M; Tiula E; Neuvonen P J
Effect of continuous venovenous haemofiltration and haemodiafiltration on the elimination of fluconazole in patients with acute renal failure.
The Journal of antimicrobial chemotherapy 1997;40(5):695-700.
1997: Kaukonen K M; Olkkola K T; Neuvonen P J
Itraconazole increases plasma concentrations of quinidine.
Clinical pharmacology and therapeutics 1997;62(5):510-7.
1997: Kivistö K T; Lamberg T S; Kantola T; Neuvonen P J
Plasma buspirone concentrations are greatly increased by erythromycin and itraconazole.
Clinical pharmacology and therapeutics 1997;62(3):348-54.
1997: Huupponen R; Hirvisalo E L; Neuvonen P
Comparison of cyclophilin binding assay and radioimmunoassay in monitoring of blood cyclosporine.
Therapeutic drug monitoring 1997;19(4):446-9.
1997: Lukkari E; Aranko K; Juhakoski A; Hakonen T; Neuvonen P J
Effect of time interval between food and drug ingestion on the absorption of oxybutynin from a controlled-release tablet.
Pharmacology & toxicology 1997;81(1):31-4.
1997: Villikka K; Kivistö K T; Lamberg T S; Kantola T; Neuvonen P J
Concentrations and effects of zopiclone are greatly reduced by rifampicin.
British journal of clinical pharmacology 1997;43(5):471-4.
1997: Jalava K M; Olkkola K T; Neuvonen P J
Itraconazole greatly increases plasma concentrations and effects of felodipine.
Clinical pharmacology and therapeutics 1997;61(4):410-5.
1997: Luomanmäki K; Tiula E; Kivistö K T; Neuvonen P J
Pharmacokinetics of diltiazem in massive overdose.
Therapeutic drug monitoring 1997;19(2):240-2.
1997: Laine K; Kivistö K T; Ojala-Karlsson P; Neuvonen P J
Effect of activated charcoal on the pharmacokinetics of pholcodine, with special reference to delayed charcoal ingestion.
Therapeutic drug monitoring 1997;19(1):46-50.
1997: Laine K; Kivistö K T; Laakso I; Neuvonen P J
Prevention of amlodipine absorption by activated charcoal: effect of delay in charcoal administration.
British journal of clinical pharmacology 1997;43(1):29-33.
1997: Villikka K; Kivistö K T; Backman J T; Olkkola K T; Neuvonen P J
Triazolam is ineffective in patients taking rifampin.
Clinical pharmacology and therapeutics 1997;61(1):8-14.
1997: Kivistö K T; Neuvonen P J; Tarssanen L
Pharmacokinetics of verapamil in overdose.
Human & experimental toxicology 1997;16(1):35-7.
1997: Lukkari E; Juhakoski A; Aranko K; Neuvonen P J
Itraconazole moderately increases serum concentrations of oxybutynin but does not affect those of the active metabolite.
European journal of clinical pharmacology 1997;52(5):403-6.
1997: Laine K; Kivistö K T; Neuvonen P J
Effect of delayed administration of activated charcoal on the absorption of conventional and slow-release verapamil.
Journal of toxicology. Clinical toxicology 1997;35(3):263-8.
1997: Ahonen J; Olkkola K T; Neuvonen P J
Effect of route of administration of fluconazole on the interaction between fluconazole and midazolam.
European journal of clinical pharmacology 1997;51(5):415-9.
1996: Partanen J; Jalava K M; Neuvonen P J
Itraconazole increases serum digoxin concentration.
Pharmacology & toxicology 1996;79(5):274-6.
1996: Laine K; Kivistö K T; Pelttari S; Neuvonen P J
The effect of activated charcoal on the absorption of fluoxetine, with special reference to delayed charcoal administration.
Pharmacology & toxicology 1996;79(5):270-3.
1996: Varhe A; Olkkola K T; Neuvonen P J
Effect of fluconazole dose on the extent of fluconazole-triazolam interaction.
British journal of clinical pharmacology 1996;42(4):465-70.
1996: Lehto P; Laine K; Kivistö K T; Neuvonen P J
The effect of pH on the in-vitro dissolution of three second-generation sulphonylurea preparations: mechanism of antacid-sulphonylurea interaction.
The Journal of pharmacy and pharmacology 1996;48(9):899-901.
1996: Neuvonen P J; Varhe A; Olkkola K T
The effect of ingestion time interval on the interaction between itraconazole and triazolam.
Clinical pharmacology and therapeutics 1996;60(3):326-31.
1996: Neuvonen P J; Jalava K M
Itraconazole drastically increases plasma concentrations of lovastatin and lovastatin acid.
Clinical pharmacology and therapeutics 1996;60(1):54-61.
1996: Varhe A; Olkkola K T; Neuvonen P J
Fluconazole, but not terbinafine, enhances the effects of triazolam by inhibiting its metabolism.
British journal of clinical pharmacology 1996;41(4):319-23.
1996: Ahonen J; Olkkola K T; Neuvonen P J
Lack of effect of antimycotic itraconazole on the pharmacokinetics or pharmacodynamics of temazepam.
Therapeutic drug monitoring 1996;18(2):124-7.
1996: Varhe A; Olkkola K T; Neuvonen P J
Diltiazem enhances the effects of triazolam by inhibiting its metabolism.
Clinical pharmacology and therapeutics 1996;59(4):369-75.
1996: Olkkola K T; Ahonen J; Neuvonen P J
The effects of the systemic antimycotics, itraconazole and fluconazole, on the pharmacokinetics and pharmacodynamics of intravenous and oral midazolam.
Anesthesia and analgesia 1996;82(3):511-6.
1996: Backman J T; Olkkola K T; Ojala M; Laaksovirta H; Neuvonen P J
Concentrations and effects of oral midazolam are greatly reduced in patients treated with carbamazepine or phenytoin.
Epilepsia 1996;37(3):253-7.
1996: Luurila H; Olkkola K T; Neuvonen P J
Interaction between erythromycin and the benzodiazepines diazepam and flunitrazepam.
Pharmacology & toxicology 1996;78(2):117-22.
1996: Backman J T; Olkkola K T; Neuvonen P J
Rifampin drastically reduces plasma concentrations and effects of oral midazolam.
Clinical pharmacology and therapeutics 1996;59(1):7-13.
1996: Jalava K M; Olkkola K T; Neuvonen P J
Effect of itraconazole on the pharmacokinetics and pharmacodynamics of zopiclone.
European journal of clinical pharmacology 1996;51(3-4):331-4.
1996: Ahonen J; Olkkola K T; Neuvonen P J
The effect of the antimycotic itraconazole on the pharmacokinetics and pharmacodynamics of diazepam.
Fundamental & clinical pharmacology 1996;10(3):314-8.
1996: Lukkari E; Castrèn-Kortekangas P; Juhakoski A; Löyttyniemi E; Aranko K; Neuvonen P J
Effect of food on the bioavailability of oxybutynin from a controlled release tablet.
European journal of clinical pharmacology 1996;50(3):221-3.
1995: Ahonen J; Olkkola K T; Neuvonen P J
Effect of itraconazole and terbinafine on the pharmacokinetics and pharmacodynamics of midazolam in healthy volunteers.
British journal of clinical pharmacology 1995;40(3):270-2.
1995: Hukkinen S K; Varhe A; Olkkola K T; Neuvonen P J
Plasma concentrations of triazolam are increased by concomitant ingestion of grapefruit juice.
Clinical pharmacology and therapeutics 1995;58(2):127-31.
1995: Neuvonen P J; Suhonen R
Itraconazole interacts with felodipine.
Journal of the American Academy of Dermatology 1995;33(1):134-5.
1995: Backman J T; Olkkola K T; Neuvonen P J
Azithromycin does not increase plasma concentrations of oral midazolam.
International journal of clinical pharmacology and therapeutics 1995;33(6):356-9.
1995: Luurila H; Olkkola K T; Neuvonen P J
Interaction between erythromycin and nitrazepam in healthy volunteers.
Pharmacology & toxicology 1995;76(4):255-8.
1994: Varhe A; Olkkola K T; Neuvonen P J
Oral triazolam is potentially hazardous to patients receiving systemic antimycotics ketoconazole or itraconazole.
Clinical pharmacology and therapeutics 1994;56(6 Pt 1):601-7.
1994: Luurila H; Olkkola K T; Neuvonen P J
Lack of interaction of erythromycin with temazepam.
Therapeutic drug monitoring 1994;16(6):548-51.
1994: Aranko K; Luurila H; Backman J T; Neuvonen P J; Olkkola K T
The effect of erythromycin on the pharmacokinetics and pharmacodynamics of zopiclone.
British journal of clinical pharmacology 1994;38(4):363-7.
1994: Neuvonen P J; Kivistö K T
Enhancement of drug absorption by antacids. An unrecognised drug interaction.
Clinical pharmacokinetics 1994;27(2):120-8.
1994: Roivas L; Kivistö K T; Neuvonen P J
Desorption of furosemide from charcoal in vitro and in man.
International journal of clinical pharmacology and therapeutics 1994;32(7):365-9.
1994: Laine K; Kivistö K T; Neuvonen P J
The effect of activated charcoal on the absorption and elimination of astemizole.
Human & experimental toxicology 1994;13(7):502-5.
1994: Roivas L; Neuvonen P J
Drug adsorption onto activated charcoal as a means of formulation.
Methods and findings in experimental and clinical pharmacology 1994;16(5):367-72.
1994: Hynynen M; Hynninen M; Soini H; Neuvonen P J; Heinonen J
Plasma concentration and protein binding of alfentanil during high-dose infusion for cardiac surgery.
British journal of anaesthesia 1994;72(5):571-6.
1994: Olkkola K T; Backman J T; Neuvonen P J
Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole.
Clinical pharmacology and therapeutics 1994;55(5):481-5.
1994: Backman J T; Olkkola K T; Aranko K; Himberg J J; Neuvonen P J
Dose of midazolam should be reduced during diltiazem and verapamil treatments.
British journal of clinical pharmacology 1994;37(3):221-5.
1994: Roivas L; Ojala-Karlsson P; Neuvonen P J
The bioavailability of two beta-blockers preadsorbed onto charcoal.
Methods and findings in experimental and clinical pharmacology 1994;16(2):125-32.
1994: Lehto P; Kivistö K T; Neuvonen P J
The effect of ferrous sulphate on the absorption of norfloxacin, ciprofloxacin and ofloxacin.
British journal of clinical pharmacology 1994;37(1):82-5.
1994: Kaila T; Roivas L; Neuvonen P J
Receptor binding assays in analysing the bioavailability and pharmacodynamic bioequivalence of active drug moieties. A study of metoprolol.
European journal of clinical pharmacology 1994;46(3):237-42.
1994: Kivistö K T; Kallio A; Neuvonen P J
Pharmacokinetics and pharmacodynamics of transdermal dexmedetomidine.
European journal of clinical pharmacology 1994;46(4):345-9.
1993: Kivistö K T; Lehto P; Neuvonen P J
The effects of different doses of sodium bicarbonate on the absorption and activity of non-micronized glibenclamide.
International journal of clinical pharmacology, therapy, and toxicology 1993;31(5):236-40.
1993: Olkkola K T; Aranko K; Luurila H; Hiller A; Saarnivaara L; Himberg J J; Neuvonen P J
A potentially hazardous interaction between erythromycin and midazolam.
Clinical pharmacology and therapeutics 1993;53(3):298-305.
1993: Kuitunen A; Hynynen M; Salmenperä M; Rasi V; Järvinen A; Scheinin M; Neuvonen P J; Fyhrquist F
Anaesthesia affects plasma concentrations of vasopressin, von Willebrand factor and coagulation factor VIII in cardiac surgical patients.
British journal of anaesthesia 1993;70(2):173-80.
1993: Pohjola-Sintonen S; Viitasalo M; Toivonene L; Neuvonen P
Torsades de pointes after terfenadine-itraconazole interaction.
BMJ (Clinical research ed.) 1993;306(6871):186.
1993: Pohjola-Sintonen S; Viitasalo M; Toivonen L; Neuvonen P
Itraconazole prevents terfenadine metabolism and increases risk of torsades de pointes ventricular tachycardia.
European journal of clinical pharmacology 1993;45(2):191-3.
1992: Laine K; Kivistö K T; Neuvonen P J
Failure of oral activated charcoal to accelerate the elimination of amiodarone and chloroquine.
Human & experimental toxicology 1992;11(6):491-4.
1992: Roivas L; Neuvonen P J
Reversible adsorption of nicotinic acid onto charcoal in vitro.
Journal of pharmaceutical sciences 1992;81(9):917-9.
1992: Neuvonen P J; Kivistö K T
Milk and yoghurt do not impair the absorption of ofloxacin.
British journal of clinical pharmacology 1992;33(3):346-8.
1992: Neuvonen P J; Kivistö K T; Laine K; Pyykkö K
Prevention of chloroquine absorption by activated charcoal.
Human & experimental toxicology 1992;11(2):117-20.
1992: Kivistö K T; Ojala-Karlsson P; Neuvonen P J
Inhibition of norfloxacin absorption by dairy products.
Antimicrobial agents and chemotherapy 1992;36(2):489-91.
1992: Kivistö K T; Neuvonen P J
Effect of magnesium hydroxide on the absorption and efficacy of tolbutamide and chlorpropamide.
European journal of clinical pharmacology 1992;42(6):675-9.
1991: Neuvonen P J; Kivistö K T; Lehto P
Interference of dairy products with the absorption of ciprofloxacin.
Clinical pharmacology and therapeutics 1991;50(5 Pt 1):498-502.
1991: Neuvonen P J; Roivas L; Laine K; Sundholm O
The bioavailability of sustained release nicotinic acid formulations.
British journal of clinical pharmacology 1991;32(4):473-6.
1991: Kivistö K T; Neuvonen P J
Effect of activated charcoal on the absorption of amiodarone.
Human & experimental toxicology 1991;10(5):327-9.
1991: Neuvonen P J; Kivistö K T
The effects of magnesium hydroxide on the absorption and efficacy of two glibenclamide preparations.
British journal of clinical pharmacology 1991;32(2):215-20.
1991: Tigerstedt I; Tammisto T; Neuvonen P J
The efficacy of intravenous indomethacin in prevention of postoperative pain.
Acta anaesthesiologica Scandinavica 1991;35(6):535-40.
1991: Neuvonen P J
The effect of magnesium hydroxide on the oral absorption of ibuprofen, ketoprofen and diclofenac.
British journal of clinical pharmacology 1991;31(3):263-6.
1991: Kivistö K T; Neuvonen P J
Enhancement of absorption and effect of glipizide by magnesium hydroxide.
Clinical pharmacology and therapeutics 1991;49(1):39-43.
1991: Kivistö K T; Neuvonen P J
Differential effects of sodium bicarbonate and aluminium hydroxide on the absorption and activity of glipizide.
European journal of clinical pharmacology 1991;40(4):383-6.
1990: Kivistö K T; Neuvonen P J
The effect of cholestyramine and activated charcoal on glipizide absorption.
British journal of clinical pharmacology 1990;30(5):733-6.
1990: Kivistö K T; Neuvonen P J
Effect of activated charcoal on frusemide induced diuresis: a human class experiment for medical students.
British journal of clinical pharmacology 1990;30(3):496-8.
1990: Iivanainen M; Waltimo O; Tokola O; Parantainen J; Tamminen M; Allonen H; Neuvonen P J
A controlled study with taltrimide and sodium valproate: valproate effective in partial epilepsy.
Acta neurologica Scandinavica 1990;82(2):121-5.
1990: Hirvisalo E L; Kivistö K T; Neuvonen P J
Therapeutic cyclosporine monitoring: comparison of radioimmunoassay and high-performance liquid chromatography methods in organ transplant recipients.
Therapeutic drug monitoring 1990;12(4):353-8.
1990: Bardy A H; Hiilesmaa V K; Teramo K; Neuvonen P J
Protein binding of antiepileptic drugs during pregnancy, labor, and puerperium.
Therapeutic drug monitoring 1990;12(1):40-6.
1989: Hynynen M; Olkkola K T; Näveri E; Palojoki R; Neuvonen P J; Heinonen J
Thiopentone pharmacokinetics during cardiopulmonary bypass with a nonpulsatile or pulsatile flow.
Acta anaesthesiologica Scandinavica 1989;33(7):554-60.
1989: Neuvonen P J; Kuusisto P; Manninen V; Vapaatalo H; Miettinen T A
The mechanism of the hypocholesterolaemic effect of activated charcoal.
European journal of clinical investigation 1989;19(3):251-4.
1989: Taivainen T; Hiller A; Rosenberg P H; Neuvonen P
The effect of continuous intravenous indomethacin infusion on bleeding time and postoperative pain in patients undergoing emergency surgery of the lower extremities.
Acta anaesthesiologica Scandinavica 1989;33(1):58-60.
1989: Neuvonen P J; Kivistö K T
The clinical significance of food-drug interactions: a review.
The Medical journal of Australia 1989;150(1):36-40.
1989: Neuvonen P J; Kuusisto P; Vapaatalo H; Manninen V
Activated charcoal in the treatment of hypercholesterolaemia: dose-response relationships and comparison with cholestyramine.
European journal of clinical pharmacology 1989;37(3):225-30.
1988: Neuvonen P J; Kivistö K; Hirvisalo E L
Effects of resins and activated charcoal on the absorption of digoxin, carbamazepine and frusemide.
British journal of clinical pharmacology 1988;25(2):229-33.
1988: Neuvonen P J; Olkkola K T
Oral activated charcoal in the treatment of intoxications. Role of single and repeated doses.
Medical toxicology and adverse drug experience 1988;3(1):33-58.
1988: Neuvonen P J; Kivistö K T
Effect of magnesium hydroxide on the absorption of tolfenamic and mefenamic acids.
European journal of clinical pharmacology 1988;35(5):495-501.
1988: Riikonen R; Santavuori P; Meretoja O; Sainio K; Neuvonen P J; Tokola R A
Can barbiturate anaesthesia cure infantile spasms?
Brain & development 1988;10(5):300-4.
1987: Neuvonen P J; Tokola O
Bioavailability of rectally administered carbamazepine mixture.
British journal of clinical pharmacology 1987;24(6):839-41.
1987: Tiula E; Tallgren L G; Neuvonen P J
Serum protein binding of phenytoin, diazepam and propranolol in chronic renal diseases.
International journal of clinical pharmacology, therapy, and toxicology 1987;25(10):545-52.
1987: Tiula E; Haapanen E J; Neuvonen P J
Factors affecting serum protein binding of phenytoin, diazepam and propranolol in acute renal diseases.
International journal of clinical pharmacology, therapy, and toxicology 1987;25(9):469-75.
1987: Keränen T; Partanen V S; Koivisto K; Tokola O; Neuvonen P J; Riekkinen P J
Effects of taltrimide, an experimental taurine derivative, on photoconvulsive response in epileptic patients.
Epilepsia 1987;28(2):133-7.
1986: Koivisto K; Sivenius J; Keränen T; Partanen J; Riekkinen P; Gothoni G; Tokola O; Neuvonen P J
Clinical trial with an experimental taurine derivative, taltrimide, in epileptic patients.
Epilepsia 1986;27(1):87-90.

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