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Edward Neuwelt

Research Profile

Physiology

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TOP 3
Eric M Thompson; Gregory L Pishko; Leslie L Muldoon; Edward A Neuwelt
Inhibition of SUR1 Decreases the Vascular Permeability of Cerebral Metastases.
Csanad G Varallyay; William D Rooney; Eric Earl; Rongwei Fu; Seymur Gahramanov; Xin Li; Brendan Moloney; Leslie L Muldoon; Eric Nesbit; Edward A Neuwelt
High-resolution steady-state cerebral blood volume maps in patients with central nervous system neoplasms using ferumoxytol, a superparamagnetic iron oxide nanoparticle.
Neha Garg; Bronwyn Hamilton; Edward A Neuwelt; Randy Woltjer; James T Rosenbaum
A 67-year-old woman receiving tumor necrosis factor α inhibitor therapy presenting with neurologic dysfunction.

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2013: Eric M Thompson; Gregory L Pishko; Leslie L Muldoon; Edward A Neuwelt
Inhibition of SUR1 Decreases the Vascular Permeability of Cerebral Metastases.
Neoplasia (New York, N.Y.) 2013;15(5):535-43.
2013: Csanad G Varallyay; William D Rooney; Eric Earl; Rongwei Fu; Seymur Gahramanov; Xin Li; Brendan Moloney; Leslie L Muldoon; Eric Nesbit; Edward A Neuwelt
High-resolution steady-state cerebral blood volume maps in patients with central nervous system neoplasms using ferumoxytol, a superparamagnetic iron oxide nanoparticle.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2013;33(5):780-6.
2013: Neha Garg; Bronwyn Hamilton; Edward A Neuwelt; Randy Woltjer; James T Rosenbaum
A 67-year-old woman receiving tumor necrosis factor α inhibitor therapy presenting with neurologic dysfunction.
Arthritis care & research 2013;65(4):658-65.
2013: Seymur Gahramanov; B Hamilton; Dale F Kraemer; Xin Li; Leslie L Muldoon; William D Rooney; Csanad G Varallyay; Rongwei Fu; Edward A Neuwelt
Pseudoprogression of glioblastoma after chemo- and radiation therapy: diagnosis by using dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging with ferumoxytol versus gadoteridol and correlation with survival.
Radiology 2013;266(3):842-52.
2013: Eric M Thompson; Nathaniel L Whitney; Y Jeffrey Wu; Edward A Neuwelt
The effect of alpha-v integrin inhibition on the malignant characteristics of medulloblastoma.
Journal of neurosurgery. Pediatrics 2013;11(1):60-7.
2013: Leslie L Muldoon; John R Ohlfest; Alexandre Prat; Maurizio Scarpa; Richard J Smeyne; Jorge I Alvarez; David J Begley; Ruben J Boado; Gregory J del Zoppo; Nancy D Doolittle; Lester R Drewes; Britta Engelhardt; John M Hallenbeck; Russell R Lonser; Edward A Neuwelt
Immunologic privilege in the central nervous system and the blood-brain barrier.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2013;33(1):13-21.
2012: Y Jeffrey Wu; Seymur Gahramanov; Dale F Kraemer; Deborah J Marshall; Leslie L Muldoon; Edward A Neuwelt
Targeting αV-integrins decreased metastasis and increased survival in a nude rat breast cancer brain metastasis model.
Journal of neuro-oncology 2012;110(1):27-36.
2012: Eric M Thompson; Edit Dósa; Seymur Gahramanov; Daniel J Guillaume; B Hamilton; Xin Li; Kellie J Nazemi; Edward A Neuwelt
Dual contrast perfusion MRI in a single imaging session for assessment of pediatric brain tumors.
Journal of neuro-oncology 2012;109(1):105-14.
2012: Penelope R Brock; Kathleen Campbell; Kay W Chang; Brian J Fligor; David R Freyer; Kristin R Knight; Kaukab Rajput; Shahrad R Rassekh; Peter S Steyger; Michael Sullivan; Brian W Blakley; Edward A Neuwelt
Platinum-induced ototoxicity in children: a consensus review on mechanisms, predisposition, and protection, including a new International Society of Pediatric Oncology Boston ototoxicity scale.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(19):2408-17.
2012: Daniel J Guillaume; Kristin Knight; Dale F Kraemer; Carol Marquez; Dianna M E Bardo; Edward A Neuwelt
Cerebrospinal fluid shunting and hearing loss in patients treated for medulloblastoma.
Journal of neurosurgery. Pediatrics 2012;9(4):421-7.
2011: Seymur Gahramanov; Xin Li; Leslie L Muldoon; Edward A Neuwelt
Improved perfusion MR imaging assessment of intracerebral tumor blood volume and antiangiogenic therapy efficacy in a rat model with ferumoxytol.
Radiology 2011;261(3):796-804.
2011: Abigail J Rao; Hector R Cintrón-Colón; S Humayun Gultekin; Edward A Neuwelt; Brian T Ragel
Late occurrence of drop metastasis to the spine in a case of esthesioneuroblastoma.
Journal of neurosurgery. Spine 2011;15(5):571-5.
2011: B Hamilton; Eric G Nesbit; Gary M Nesbit; Edit Dosa; Seymur Gahramanov; Joshua Raines; Bill Rooney; Edward A Neuwelt
Comparative analysis of ferumoxytol and gadoteridol enhancement using T1- and T2-weighted MRI in neuroimaging.
AJR. American journal of roentgenology 2011;197(4):981-8.
2011: Edit Dósa; Suchita Tuladhar; Leslie L Muldoon; Bronwyn E Hamilton; William D Rooney; Edward A Neuwelt
MRI using ferumoxytol improves the visualization of central nervous system vascular malformations.
Stroke; a journal of cerebral circulation 2011;42(6):1581-8.
2011: Eric M Thompson; Edit Dosa; Dale F Kraemer; Edward A Neuwelt
Correlation of MRI sequences to assess progressive glioblastoma multiforme treated with bevacizumab.
Journal of neuro-oncology 2011;103(2):353-60.
2011: Leslie L Muldoon; Seth J Lewin; Edit Dósa; Dale F Kraemer; Michael A Pagel; Nancy D Doolittle; Edward A Neuwelt
Imaging and therapy with rituximab anti-CD20 immunotherapy in an animal model of central nervous system lymphoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(8):2207-15.
2011: Edward A Neuwelt; Björn Bauer; Christoph Fahlke; Gert Fricker; costantino iadecola; Damir Janigro; Luc Leybaert; Zoltán Molnár; Martha E O'Donnell; John T Povlishock; Norman R Saunders; Frank R Sharp; Danica Stanimirovic; Ryan J Watts; Lester R Drewes
Engaging neuroscience to advance translational research in brain barrier biology.
Nature reviews. Neuroscience 2011;12(3):169-82.
2011: Troy H Dillard; Sakir Humayun Gultekin; Johnny B Delashaw; Christine G (Chris) Yedinak; Edward A Neuwelt; Maria Fleseriu
Temozolomide for corticotroph pituitary adenomas refractory to standard therapy.
Pituitary 2011;14(1):80-91.
2011: Edit Dósa; Daniel J Guillaume; Marianne Haluska; Cynthia A Lacy; Bronwyn E Hamilton; Jeffrey M Njus; William D Rooney; Dale F Kraemer; Leslie L Muldoon; Edward A Neuwelt
Magnetic resonance imaging of intracranial tumors: intra-patient comparison of gadoteridol and ferumoxytol.
Neuro-oncology 2011;13(2):251-60.
2011: Seymur Gahramanov; Ahmed M Raslan; Leslie L Muldoon; B Hamilton; William D Rooney; Csanad G Varallyay; Jeffrey M Njus; Marianne Haluska; Edward A Neuwelt
Potential for differentiation of pseudoprogression from true tumor progression with dynamic susceptibility-weighted contrast-enhanced magnetic resonance imaging using ferumoxytol vs. gadoteridol: a pilot study.
International journal of radiation oncology, biology, physics 2011;79(2):514-23.
2011: Eric M Thompson; Eugene P Frenkel; Edward A Neuwelt
The paradoxical effect of bevacizumab in the therapy of malignant gliomas.
Neurology 2011;76(1):87-93.
2011: Leslie L Muldoon; Seymur Gahramanov; Xin Li; Deborah J Marshall; Dale F Kraemer; Edward A Neuwelt
Dynamic magnetic resonance imaging assessment of vascular targeting agent effects in rat intracerebral tumor models.
Neuro-oncology 2011;13(1):51-60.
2010: Xin Li; William D Rooney; Csanád G Várallyay; Seymur Gahramanov; Leslie L Muldoon; James A Goodman; Ian J Tagge; Audrey H Selzer; Martin M Pike; Edward A Neuwelt; Charles S Springer
Dynamic-contrast-enhanced-MRI with extravasating contrast reagent: rat cerebral glioma blood volume determination.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2010;206(2):190-9.
2010: Eric M Thompson; Edit Dosa; Dale F Kraemer; Edward A Neuwelt
Treatment with bevacizumab plus carboplatin for recurrent malignant glioma.
Neurosurgery 2010;67(1):87-93.
2010: Edward A Neuwelt; Penelope Brock
Critical need for international consensus on ototoxicity assessment criteria.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(10):1630-2.
2010: Dennis N Bourdette; Edward A Neuwelt; Nancy D Doolittle; Dale Kraemer
Reply.
Annals of neurology 2010;67(2):270-1; author reply 271.
2010: Suellen Pommier; Glenda G Quan; Dara Christante; Patrick Muller; Amy E H Newell; Susan B Olson; Brian Diggs; Leslie L Muldoon; Edward A Neuwelt; Rodney F Pommier
Characterizing the HER2/neu status and metastatic potential of breast cancer stem/progenitor cells.
Annals of surgical oncology 2010;17(2):613-23.
2010: Daniel Guillaume; Nancy D Doolittle; Seymur Gahramanov; Nancy A Hedrick; Johnny B Delashaw; Edward A Neuwelt
Intra-arterial chemotherapy with osmotic blood-brain barrier disruption for aggressive oligodendroglial tumors: results of a phase I study.
Neurosurgery 2010;66(1):48-58; discussion 58.
2010: Jason S Weinstein; Csanad G Varallyay; Edit Dosa; Seymur Gahramanov; B Hamilton; William D Rooney; Leslie L Muldoon; Edward A Neuwelt
Superparamagnetic iron oxide nanoparticles: diagnostic magnetic resonance imaging and potential therapeutic applications in neurooncology and central nervous system inflammatory pathologies, a review.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2010;30(1):15-35.
2009: Alexander J Neuwelt; Y Jeffrey Wu; Narcyz Knap; Marcin Losin; Edward A Neuwelt; Michael A Pagel; Steven Warmann; Joerg Fuchs; Piotr Czauderna; Michal Wozniak
Using acetaminophen's toxicity mechanism to enhance cisplatin efficacy in hepatocarcinoma and hepatoblastoma cell lines.
Neoplasia (New York, N.Y.) 2009;11(10):1003-11.
2009: Kristoph Jahnke; Leslie L Muldoon; Csanad G Varallyay; Seth J Lewin; Robert D Brown; Dale F Kraemer; Carole Soussain; Edward A Neuwelt
Efficacy and MRI of rituximab and methotrexate treatment in a nude rat model of CNS lymphoma.
Neuro-oncology 2009;11(5):503-13.
2009: Lilyana Angelov; Nancy D Doolittle; Dale F Kraemer; Tali Siegal; Gene H Barnett; David M Peereboom; Glen Stevens; John McGregor; Kristoph Jahnke; Cynthia A Lacy; Nancy A Hedrick; Edna Shalom; Sandra Ference; Susan Bell; Lisa Sorenson; Rose Marie Tyson; Marianne Haluska; Edward A Neuwelt
Blood-brain barrier disruption and intra-arterial methotrexate-based therapy for newly diagnosed primary CNS lymphoma: a multi-institutional experience.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(21):3503-9.
2009: Richard Tritz; Michelle J Hickey; Amy H Lin; Philipp Hadwiger; Dinah W Y Sah; Edward A Neuwelt; Barbara M Mueller; Carol A Kruse
FAPP2 gene downregulation increases tumor cell sensitivity to Fas-induced apoptosis.
Biochemical and biophysical research communications 2009;383(2):167-71.
2009: Csanad G Varallyay; Leslie L Muldoon; Seymur Gahramanov; Yingjen J Wu; James A Goodman; Xin Li; Martin M Pike; Edward A Neuwelt
Dynamic MRI using iron oxide nanoparticles to assess early vascular effects of antiangiogenic versus corticosteroid treatment in a glioma model.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2009;29(4):853-60.
2009: Kristoph Jahnke; Leslie L Muldoon; Csanad G Varallyay; Seth J Lewin; Dale F Kraemer; Edward A Neuwelt
Bevacizumab and carboplatin increase survival and asymptomatic tumor volume in a glioma model.
Neuro-oncology 2009;11(2):142-50.
2009: Edward A Neuwelt; B Hamilton; Csanad G Varallyay; William R Rooney; Robert D Edelman; Paula M Jacobs; Suzanne Watnick
Ultrasmall superparamagnetic iron oxides (USPIOs): a future alternative magnetic resonance (MR) contrast agent for patients at risk for nephrogenic systemic fibrosis (NSF)?
Kidney international 2009;75(5):465-74.
2009: Yingjen Jeffrey Wu; Leslie L Muldoon; D Thomas Dickey; Seth J Lewin; Csanad G Varallyay; Edward A Neuwelt
Cyclophosphamide enhances human tumor growth in nude rat xenografted tumor models.
Neoplasia (New York, N.Y.) 2009;11(2):187-95.
2008: S A Grimm; C A McCannel; Antonio M P Omuro; Andrés J M Ferreri; J-Y Blay; Edward A Neuwelt; Tali Siegal; Tracy T Batchelor; Kristoph Jahnke; Tamara N Shenkier; A J Hall; Francesc Graus; Ulrich Herrlinger; David Schiff; Jeffrey J Raizer; J Rubenstein; Normand Laperriere; Eckhard Thiel; Nancy D Doolittle; Fabio M Iwamoto; Lauren E Abrey
Primary CNS lymphoma with intraocular involvement: International PCNSL Collaborative Group Report.
Neurology 2008;71(17):1355-60.
2008: D Thomas Dickey; Nancy D Doolittle; Dale F Kraemer; Leslie L Muldoon; Darryl R Peterson; Edward A Neuwelt
Effect of N-acetylcysteine route of administration on chemoprotection against cisplatin-induced toxicity in rat models.
Cancer chemotherapy and pharmacology 2008;62(2):235-41.
2008: David Stenstrom; Leslie L Muldoon; Hector Armijo-Medina; Suzanne Watnick; Nancy D Doolittle; John A Kaufman; Darryl R Peterson; Joseph S Bubalo; Edward A Neuwelt
N-acetylcysteine use to prevent contrast medium-induced nephropathy: premature phase III trials.
Journal of vascular and interventional radiology : JVIR 2008;19(3):309-18.
2008: Justine R Smith; W W Henderson; James T Rosenbaum; Edward A Neuwelt; Ashlee V Moses
Cultured human endothelial cells expressing HIV-1 Vpu and Tat support the expansion of malignant B cells from primary central nervous system lymphoma.
The British journal of ophthalmology 2008;92(2):297-9.
2008: Kristoph Jahnke; Dale F Kraemer; Kristin R Knight; David Fortin; Susan Bell; Nancy D Doolittle; Leslie L Muldoon; Edward A Neuwelt
Intraarterial chemotherapy and osmotic blood-brain barrier disruption for patients with embryonal and germ cell tumors of the central nervous system.
Cancer 2008;112(3):581-8.
2008: Nancy D Doolittle; Lauren E Abrey; Tamara N Shenkier; Siegal Tali; Jacoline E C Bromberg; Edward A Neuwelt; Carole Soussain; Kristoph Jahnke; Patrick Johnston; Gerald Illerhaus; David Schiff; Tracy Batchelor; Silvia Montoto; Dale F Kraemer; Emanuele Zucca
Brain parenchyma involvement as isolated central nervous system relapse of systemic non-Hodgkin lymphoma: an International Primary CNS Lymphoma Collaborative Group report.
Blood 2008;111(3):1085-93.
2008: Theresa M Harned; Ondrej Kalous; Alexander Neuwelt; Jason Loera; Lingyun Ji; Peter Iovine; Richard Sposto; Edward A Neuwelt; Charles Patrick Reynolds
Sodium thiosulfate administered six hours after cisplatin does not compromise antineuroblastoma activity.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(2):533-40.
2008: Edward A Neuwelt; N Joan Abbott; Lauren E Abrey; William A Banks; Brian W Blakley; Thomas Davis; Britta Engelhardt; Paula Grammas; Maiken Nedergaard; John G Nutt; William Pardridge; Gary A Rosenberg; Quentin R Smith; Lester Drewes
Strategies to advance translational research into brain barriers.
Lancet neurology 2008;7(1):84-96.
2007: Y Jeffrey Wu; Leslie L Muldoon; Csanad Varallyay; Sheila Markwardt; Richard Jones; Edward A Neuwelt
In vivo leukocyte labeling with intravenous ferumoxides/protamine sulfate complex and in vitro characterization for cellular magnetic resonance imaging.
American journal of physiology. Cell physiology 2007;293(5):C1698-708.
2007: S A Grimm; J S Pulido; Kristoph Jahnke; David Schiff; A J Hall; Tamara N Shenkier; Tali Siegal; Nancy D Doolittle; Tracy T Batchelor; Ulrich Herrlinger; Edward A Neuwelt; Normand Laperriere; M C Chamberlain; J Y Blay; Andrés J M Ferreri; Antonio M P Omuro; Eckhard Thiel; Lauren E Abrey
Primary intraocular lymphoma: an International Primary Central Nervous System Lymphoma Collaborative Group Report.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2007;18(11):1851-5.
2007: Kristoph Jahnke; Eckhard Thiel; Lauren E Abrey; Edward A Neuwelt; Agnieszka Korfel
Diagnosis and management of primary intraocular lymphoma: an update.
Clinical ophthalmology (Auckland, N.Z.) 2007;1(3):247-58.
2007: Nancy D Doolittle; Kristoph Jahnke; Richard Belanger; Deborah A Ryan; Robert W Nance; Cynthia Lacy; Rose Marie Tyson; Marianne Haluska; Nancy A Hedrick; Csanad Varallyay; Edward A Neuwelt
Potential of chemo-immunotherapy and radioimmunotherapy in relapsed primary central nervous system (CNS) lymphoma.
Leukemia & lymphoma 2007;48(9):1712-20.
2007: James T Rosenbaum; Tammy M Martin; Kendra H Farris; Richard B Rosenbaum; Edward A Neuwelt
Can medical schools teach high school students to be scientists?
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(9):1954-7.
2007: Leslie L Muldoon; Carole Soussain; Kristoph Jahnke; Conrad Johanson; Tali Siegal; Quentin R Smith; Walter A Hall; Kullervo Hynynen; Peter D Senter; David M Peereboom; Edward A Neuwelt
Chemotherapy delivery issues in central nervous system malignancy: a reality check.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(16):2295-305.
2007: Carole Soussain; Leslie L Muldoon; Csanad Varallyay; Kristoph Jahnke; Luciana DePaula; Edward A Neuwelt
Characterization and magnetic resonance imaging of a rat model of human B-cell central nervous system lymphoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(8):2504-11.
2007: Edward A Neuwelt; Csanád G Várallyay; Sándor Manninger; Diána Solymosi; Marianne Haluska; Matthew A Hunt; Gary M Nesbit; Alexander A Stevens; Michael Jerosch-Herold; Paula M Jacobs; John M Hoffman
The potential of ferumoxytol nanoparticle magnetic resonance imaging, perfusion, and angiography in central nervous system malignancy: a pilot study.
Neurosurgery 2007;60(4):601-11; discussion 611-2.
2007: Kristin R Knight; Dale F Kraemer; Christiane Winter; Edward A Neuwelt
Early changes in auditory function as a result of platinum chemotherapy: use of extended high-frequency audiometry and evoked distortion product otoacoustic emissions.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(10):1190-5.
2007: Nancy D Doolittle; David M Peereboom; Gregory A Christoforidis; Walter A Hall; Diane Palmieri; Penelope R Brock; Kathleen Campbell; D Thomas Dickey; Leslie L Muldoon; Brian Patrick O'Neill; Darryl R Peterson; Bradley Pollock; Carole Soussain; Quentin R Smith; Rose Marie Tyson; Edward A Neuwelt
Delivery of chemotherapy and antibodies across the blood-brain barrier and the role of chemoprotection, in primary and metastatic brain tumors: report of the Eleventh Annual Blood-Brain Barrier Consortium meeting.
Journal of neuro-oncology 2007;81(1):81-91.
2006: Edward A Neuwelt; Kristin Gilmer-Knight; Cynthia Lacy; H Stacy Nicholson; Dale F Kraemer; Nancy D Doolittle; Gregory W Hornig; Leslie L Muldoon
Toxicity profile of delayed high dose sodium thiosulfate in children treated with carboplatin in conjunction with blood-brain-barrier disruption.
Pediatric blood & cancer 2006;47(2):174-82.
2006: Kristoph Jahnke; Agnieszka Korfel; Brian Patrick O'Neill; Jean-Yves Blay; Lauren E Abrey; Peter Martus; Philip Poortmans; Tamara N Shenkier; Tracy T Batchelor; Edward A Neuwelt; Jeffrey J Raizer; David Schiff; Hendrik Pels; Ulrich Herrlinger; Harald Stein; Eckhard Thiel
International study on low-grade primary central nervous system lymphoma.
Annals of neurology 2006;59(5):755-62.
2006: Walter A Hall; Nancy D Doolittle; Megan Daman; Patti K Bruns; Leslie L Muldoon; David Fortin; Edward A Neuwelt
Osmotic blood-brain barrier disruption chemotherapy for diffuse pontine gliomas.
Journal of neuro-oncology 2006;77(3):279-84.
2006: Leslie L Muldoon; Paul G. Tratnyek; Paula M Jacobs; Nancy D Doolittle; G A Christoforidis; J A Frank; M Lindau; P R Lockman; S P Manninger; Y Qiang; A M Spence; S I Stupp; M Zhang; Edward A Neuwelt
Imaging and nanomedicine for diagnosis and therapy in the central nervous system: report of the eleventh annual Blood-Brain Barrier Disruption Consortium meeting.
AJNR. American journal of neuroradiology 2006;27(3):715-21.
2006: Matthew A Hunt; Kristoph Jahnke; Tulio P Murillo; Edward A Neuwelt
Distinguishing primary central nervous system lymphoma from other central nervous system diseases: a neurosurgical perspective on diagnostic dilemmas and approaches.
Neurosurgical focus 2006;21(5):E3.
2006: Kristoph Jahnke; Nancy D Doolittle; Leslie L Muldoon; Edward A Neuwelt
Implications of the blood-brain barrier in primary central nervous system lymphoma.
Neurosurgical focus 2006;21(5):E11.
2005: Kristin R Knight; Dale F Kraemer; Edward A Neuwelt
Ototoxicity in children receiving platinum chemotherapy: underestimating a commonly occurring toxicity that may influence academic and social development.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(34):8588-96.
2005: Leslie L Muldoon; Manninger Sàndor; Kristina E Pinkston; Edward A Neuwelt
Imaging, distribution, and toxicity of superparamagnetic iron oxide magnetic resonance nanoparticles in the rat brain and intracerebral tumor.
Neurosurgery 2005;57(4):785-96; discussion 785-96.
2005: Sándor P Manninger; Leslie L Muldoon; Gary M Nesbit; Tulio Murillo; Paula M Jacobs; Edward A Neuwelt
An exploratory study of ferumoxtran-10 nanoparticles as a blood-brain barrier imaging agent targeting phagocytic cells in CNS inflammatory lesions.
AJNR. American journal of neuroradiology 2005;26(9):2290-300.
2005: D Thomas Dickey; Y Jeffrey Wu; Leslie L Muldoon; Edward A Neuwelt
Protection against cisplatin-induced toxicities by N-acetylcysteine and sodium thiosulfate as assessed at the molecular, cellular, and in vivo levels.
The Journal of pharmacology and experimental therapeutics 2005;314(3):1052-8.
2005: Lauren E Abrey; Tracy T Batchelor; Andrés J M Ferreri; Mary Gospodarowicz; Elisa J Pulczynski; Emanuele Zucca; Justine R Smith; Agnieszka Korfel; Carole Soussain; Lisa De Angelis; Edward A Neuwelt; Brian Patrick O'Neill; Eckhard Thiel; Tamara N Shenkier; Francesc Graus; Martin J van den Bent; John F Seymour; Philip Poortmans; James O Armitage; Franco Cavalli
Report of an international workshop to standardize baseline evaluation and response criteria for primary CNS lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(22):5034-43.
2005: Tulio Murillo; Edward A Neuwelt
USPIOs to enhance the diagnostic potential of ultrasound in tumor and other inflammatory lesions.
AJNR. American journal of neuroradiology 2005;26(6):1305-6.
2005: Rachel I Rosenberg; Dorothy L Zirkle; Edward A Neuwelt
Program self-evaluation: the evolution of an injury prevention foundation.
Journal of neurosurgery 2005;102(5):847-9.
2005: Matthew A Hunt; Attila Bagó; Edward A Neuwelt
Single-dose contrast agent for intraoperative MR imaging of intrinsic brain tumors by using ferumoxtran-10.
AJNR. American journal of neuroradiology 2005;26(5):1084-8.
2005: Tamara N Shenkier; Jean-Yves Blay; Brian Patrick O'Neill; Philip Poortmans; Eckhard Thiel; Kristoph Jahnke; Lauren E Abrey; Edward A Neuwelt; Richard Tsang; Tracy T Batchelor; Nancy Harris; Andrés J M Ferreri; Maurilio Ponzoni; Peter O'Brien; James Rubenstein; Joseph Michael Connors
Primary CNS lymphoma of T-cell origin: a descriptive analysis from the international primary CNS lymphoma collaborative group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(10):2233-9.
2005: Edward A Neuwelt; Paul E Guastadisegni; Péter Várallyay; Nancy D Doolittle
Imaging changes and cognitive outcome in primary CNS lymphoma after enhanced chemotherapy delivery.
AJNR. American journal of neuroradiology 2005;26(2):258-65.
2005: Y Jeffrey Wu; Leslie L Muldoon; Edward A Neuwelt
The chemoprotective agent N-acetylcysteine blocks cisplatin-induced apoptosis through caspase signaling pathway.
The Journal of pharmacology and experimental therapeutics 2005;312(2):424-31.
2005: Nancy D Doolittle; Lauren E Abrey; Archie Bleyer; Steven Brem; Thomas P Davis; Paula Dore-Duffy; Lester Drewes; Walter A Hall; John M Hoffman; Agnieszka Korfel; Robert L Martuza; Leslie L Muldoon; David M Peereboom; Darryl R Peterson; samuel rabkin; Quentin R Smith; Glen H J Stevens; Edward A Neuwelt
New frontiers in translational research in neuro-oncology and the blood-brain barrier: report of the tenth annual Blood-Brain Barrier Disruption Consortium Meeting.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(2 Pt 1):421-8.
2005: Julia A Staverosky; Leslie L Muldoon; Shuhua Guo; Adam J Evans; Edward A Neuwelt; Gail M Clinton
Herstatin, an autoinhibitor of the epidermal growth factor receptor family, blocks the intracranial growth of glioblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(1):335-40.
2004: Edward A Neuwelt; Péter Várallyay; Attila Bagó; Leslie L Muldoon; Gary M Nesbit; R Nixon
Imaging of iron oxide nanoparticles by MR and light microscopy in patients with malignant brain tumours.
Neuropathology and applied neurobiology 2004;30(5):456-71.
2004: D Thomas Dickey; Leslie L Muldoon; Dale F Kraemer; Edward A Neuwelt
Protection against cisplatin-induced ototoxicity by N-acetylcysteine in a rat model.
Hearing research 2004;193(1-2):25-30.
2004: Edward A Neuwelt; Michael A Pagel; Dale F Kraemer; Darryl R Peterson; Leslie L Muldoon
Bone marrow chemoprotection without compromise of chemotherapy efficacy in a rat brain tumor model.
The Journal of pharmacology and experimental therapeutics 2004;309(2):594-9.
2004: Leslie L Muldoon; P Varallyay; D F Kraemer; G Kiwic; K Pinkston; S L Walker-Rosenfeld; Edward A Neuwelt
Trafficking of superparamagnetic iron oxide particles (Combidex) from brain to lymph nodes in the rat.
Neuropathology and applied neurobiology 2004;30(1):70-9.
2004: Edward A Neuwelt
Mechanisms of disease: the blood-brain barrier.
Neurosurgery 2004;54(1):131-40; discussion 141-2.
2003: Leslie L Muldoon; Edward A Neuwelt
BR96-DOX immunoconjugate targeting of chemotherapy in brain tumor models.
Journal of neuro-oncology 2003;65(1):49-62.
2003: Andrés J M Ferreri; Lauren E Abrey; Jean-Yves Blay; Bettina Borisch; Jacob Hochman; Edward A Neuwelt; Joachim Yahalom; Emanuele Zucca; Franco Cavalli; James Armitage; Tracy Batchelor
Summary statement on primary central nervous system lymphomas from the Eighth International Conference on Malignant Lymphoma, Lugano, Switzerland, June 12 to 15, 2002.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(12):2407-14.
2002: Brian W Blakley; James I Cohen; Nancy D Doolittle; Leslie L Muldoon; Kathleen Campbell; D Thomas Dickey; Edward A Neuwelt
Strategies for prevention of toxicity caused by platinum-based chemotherapy: review and summary of the annual meeting of the Blood-Brain Barrier Disruption Program, Gleneden Beach, Oregon, March 10, 2001.
The Laryngoscope 2002;112(11):1997-2001.
2002: Robert M Quencer; Edward A Neuwelt
Advances in the understanding of the blood-brain barrier in neuro-oncology.
AJNR. American journal of neuroradiology 2002;23(10):1807-10.
2002: A Greene; P Barnett; John Robert (Jack) Crossen; G Sexton; P Ruzicka; Edward A Neuwelt
Evaluation of the THINK FIRST For KIDS injury prevention curriculum for primary students.
Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention 2002;8(3):257-8.
2002: Justine R Smith; James T Rosenbaum; David J Wilson; Nancy D Doolittle; Tali Siegal; Edward A Neuwelt; Jacob Pe'er
Role of intravitreal methotrexate in the management of primary central nervous system lymphoma with ocular involvement.
Ophthalmology 2002;109(9):1709-16.
2002: Nancy D Doolittle; Lauren E Abrey; Nicolay Ferrari; Walter A Hall; Edward R Laws; Roger E McLendon; Leslie L Muldoon; David M Peereboom; Darryl R Peterson; Charles Patrick Reynolds; Peter D Senter; Edward A Neuwelt
Targeted delivery in primary and metastatic brain tumors: summary report of the seventh annual meeting of the Blood-Brain Barrier Disruption Consortium.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(6):1702-9.
2002: Dale F Kraemer; David Fortin; Edward A Neuwelt
Chemotherapeutic dose intensification for treatment of malignant brain tumors: recent developments and future directions.
Current neurology and neuroscience reports 2002;2(3):216-24.
2002: Peter Varallyay; Gary M Nesbit; Leslie L Muldoon; Randal R Nixon; Johnny B Delashaw; James I Cohen; Annie Petrillo; Doris Rink; Edward A Neuwelt
Comparison of two superparamagnetic viral-sized iron oxide particles ferumoxides and ferumoxtran-10 with a gadolinium chelate in imaging intracranial tumors.
AJNR. American journal of neuroradiology 2002;23(4):510-9.
2001: LG Remsen; Carol M Marquez; R Garcia; L A Thrun; Edward A Neuwelt
Efficacy after sequencing of brain radiotherapy and enhanced antibody targeted chemotherapy delivery in a rodent human lung cancer brain xenograft model.
International journal of radiation oncology, biology, physics 2001;51(4):1045-9.
2001: Edward A Neuwelt; Michael A Pagel; B P Hasler; Thomas G Deloughery; Leslie L Muldoon
Therapeutic efficacy of aortic administration of N-acetylcysteine as a chemoprotectant against bone marrow toxicity after intracarotid administration of alkylators, with or without glutathione depletion in a rat model.
Cancer research 2001;61(21):7868-74.
2001: E Osztie; Péter Várallyay; Nancy D Doolittle; Cynthia Lacy; G Jones; H S Nickolson; Edward A Neuwelt
Combined intraarterial carboplatin, intraarterial etoposide phosphate, and IV Cytoxan chemotherapy for progressive optic-hypothalamic gliomas in young children.
AJNR. American journal of neuroradiology 2001;22(5):818-23.
2001: D F Kraemer; David Fortin; Nancy D Doolittle; Edward A Neuwelt
Association of total dose intensity of chemotherapy in primary central nervous system lymphoma (human non-acquired immunodeficiency syndrome) and survival.
Neurosurgery 2001;48(5):1033-40; discussion 1040-1.
2001: Nancy D Doolittle; Leslie L Muldoon; RE Brummett; Rose Marie Tyson; Cynthia Lacy; Joseph S Bubalo; Dale F Kraemer; Michael C Heinrich; J A Henry; Edward A Neuwelt
Delayed sodium thiosulfate as an otoprotectant against carboplatin-induced hearing loss in patients with malignant brain tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(3):493-500.
2001: Leslie L Muldoon; S L Walker-Rosenfeld; C Hale; S E Purcell; L C Bennett; Edward A Neuwelt
Rescue from enhanced alkylator-induced cell death with low molecular weight sulfur-containing chemoprotectants.
The Journal of pharmacology and experimental therapeutics 2001;296(3):797-805.
2001: Nancy D Doolittle; C P Anderson; Archie Bleyer; J G Cairncross; T Cloughesy; S L Eck; Paul E Guastadisegni; W A Hall; Leslie L Muldoon; Sunil J Patel; David M Peereboom; Tali Siegal; Edward A Neuwelt
Importance of dose intensity in neuro-oncology clinical trials: summary report of the Sixth Annual Meeting of the Blood-Brain Barrier Disruption Consortium.
Neuro-oncology 2001;3(1):46-54.
2000: David Fortin; CI McCormick; LG Remsen; R Nixon; Edward A Neuwelt
Unexpected neurotoxicity of etoposide phosphate administered in combination with other chemotherapeutic agents after blood-brain barrier modification to enhance delivery, using propofol for general anesthesia, in a rat model.
Neurosurgery 2000;47(1):199-207.
2000: David Fortin; E Osztie; Edward A Neuwelt
Iatrogenic arterial spasm relieved by intraarterial mannitol infusion.
AJNR. American journal of neuroradiology 2000;21(5):968-70.
2000: LG Remsen; Pamela A Trail; Ingegerd Hellström; Karl Erik Hellström; Edward A Neuwelt
Enhanced delivery improves the efficacy of a tumor-specific doxorubicin immunoconjugate in a human brain tumor xenograft model.
Neurosurgery 2000;46(3):704-9.
2000: Nancy D Doolittle; M E Miner; W A Hall; Tali Siegal; E Jerome; E Osztie; LD McAllister; Joseph S Bubalo; Dale F Kraemer; David Fortin; R Nixon; Leslie L Muldoon; Edward A Neuwelt
Safety and efficacy of a multicenter study using intraarterial chemotherapy in conjunction with osmotic opening of the blood-brain barrier for the treatment of patients with malignant brain tumors.
Cancer 2000;88(3):637-47.
2000: Leslie L Muldoon; Michael A Pagel; RA Kroll; RE Brummett; Nancy D Doolittle; E G Zuhowski; Merrill J Egorin; Edward A Neuwelt
Delayed administration of sodium thiosulfate in animal models reduces platinum ototoxicity without reduction of antitumor activity.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(1):309-15.
2000: Paul E Guastadisegni; J L Simon; J Neuwelt; R Camicioli; R Mueller; Edward A Neuwelt
Innovative intergenerational prevention programming for older adults and adolescents.
Journal of the American Geriatrics Society 2000;48(1):105-6.
2000: LD McAllister; Nancy D Doolittle; Paul E Guastadisegni; Dale F Kraemer; Cynthia Lacy; John Robert (Jack) Crossen; Edward A Neuwelt
Cognitive outcomes and long-term follow-up results after enhanced chemotherapy delivery for primary central nervous system lymphoma.
Neurosurgery 2000;46(1):51-60; discussion 60-1.
1999: David Fortin; LD McAllister; Gary M Nesbit; Nancy D Doolittle; M Miner; E J Hanson; Edward A Neuwelt
Unusual cervical spinal cord toxicity associated with intra-arterial carboplatin, intra-arterial or intravenous etoposide phosphate, and intravenous cyclophosphamide in conjunction with osmotic blood brain-barrier disruption in the vertebral artery.
AJNR. American journal of neuroradiology 1999;20(10):1794-802.
1999: LG Remsen; Michael A Pagel; CI McCormick; S A Fiamengo; G Sexton; Edward A Neuwelt
The influence of anesthetic choice, PaCO2, and other factors on osmotic blood-brain barrier disruption in rats with brain tumor xenografts.
Anesthesia and analgesia 1999;88(3):559-67.
1999: Edward A Neuwelt; N Joan Abbott; Lester Drewes; Quentin R Smith; P O Couraud; E A Chiocca; K L Audus; N H Greig; Nancy D Doolittle
Cerebrovascular Biology and the various neural barriers: challenges and future directions.
Neurosurgery 1999;44(3):604-8; discussion 608-9.
1999: Leslie L Muldoon; Michael A Pagel; RA Kroll; SM Roman-Goldstein; R S Jones; Edward A Neuwelt
A physiological barrier distal to the anatomic blood-brain barrier in a model of transvascular delivery.
AJNR. American journal of neuroradiology 1999;20(2):217-22.
1999: Andreas K Lauer; John L Wobig; W T Shults; Edward A Neuwelt; Matthew W Wilson
Severe ocular and orbital toxicity after intracarotid etoposide phosphate and carboplatin therapy.
American journal of ophthalmology 1999;127(2):230-3.
1998: RA Kroll; Michael A Pagel; Leslie L Muldoon; SM Roman-Goldstein; S A Fiamengo; Edward A Neuwelt
Improving drug delivery to intracerebral tumor and surrounding brain in a rodent model: a comparison of osmotic versus bradykinin modification of the blood-brain and/or blood-tumor barriers.
Neurosurgery 1998;43(4):879-86; discussion 886-9.
1998: SM Roman-Goldstein; A Jones; Johnny B Delashaw; Sean O McMenomey; Edward A Neuwelt
Atypical central nervous system lymphoma at the cranial base: report of four cases.
Neurosurgery 1998;43(3):613-5; discussion 615-6.
1998: Edward A Neuwelt; RE Brummett; Nancy D Doolittle; Leslie L Muldoon; RA Kroll; Michael A Pagel; R Dojan; V Church; LG Remsen; Joseph S Bubalo
First evidence of otoprotection against carboplatin-induced hearing loss with a two-compartment system in patients with central nervous system malignancy using sodium thiosulfate.
The Journal of pharmacology and experimental therapeutics 1998;286(1):77-84.
1998: Edward A Neuwelt; P A Barnett; CI McCormick; LG Remsen; RA Kroll; G Sexton
Differential permeability of a human brain tumor xenograft in the nude rat: impact of tumor size and method of administration on optimizing delivery of biologically diverse agents.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(6):1549-55.
1998: RA Kroll; Edward A Neuwelt
Outwitting the blood-brain barrier for therapeutic purposes: osmotic opening and other means.
Neurosurgery 1998;42(5):1083-99; discussion 1099-100.
1998: S A Dahlborg; Annie Petrillo; John Robert (Jack) Crossen; SM Roman-Goldstein; Nancy D Doolittle; K H Fuller; Edward A Neuwelt
The potential for complete and durable response in nonglial primary brain tumors in children and young adults with enhanced chemotherapy delivery.
The cancer journal from Scientific American 1998;4(2):110-24.
1997: B C Fishburne; David J Wilson; James T Rosenbaum; Edward A Neuwelt
Intravitreal methotrexate as an adjunctive treatment of intraocular lymphoma.
Archives of ophthalmology 1997;115(9):1152-6.
1997: LG Remsen; CI McCormick; G Sexton; H D Pearse; R Garcia; Michele K Mass; SM Roman-Goldstein; Edward A Neuwelt
Long-term toxicity and neuropathology associated with the sequencing of cranial irradiation and enhanced chemotherapy delivery.
Neurosurgery 1997;40(5):1034-40; discussion 1040-2.
1996: S A Dahlborg; W D Henner; John Robert (Jack) Crossen; C M Tableman; A Petrillo; Rita M Braziel; Edward A Neuwelt
Non-AIDS primary CNS lymphoma: first example of a durable response in a primary brain tumor using enhanced chemotherapy delivery without cognitive loss and without radiotherapy.
The cancer journal from Scientific American 1996;2(3):166-74.
1996: RA Kroll; Michael A Pagel; Leslie L Muldoon; SM Roman-Goldstein; Edward A Neuwelt
Increasing volume of distribution to the brain with interstitial infusion: dose, rather than convection, might be the most important factor.
Neurosurgery 1996;38(4):746-52; discussion 752-4.
1996: LG Remsen; CI McCormick; SM Roman-Goldstein; G Nilaver; R Weissleder; Alexei Bogdanov; I Hellström; RA Kroll; Edward A Neuwelt
MR of carcinoma-specific monoclonal antibody conjugated to monocrystalline iron oxide nanoparticles: the potential for noninvasive diagnosis.
AJNR. American journal of neuroradiology 1996;17(3):411-8.
1996: Edward A Neuwelt; R E Brummett; LG Remsen; RA Kroll; Michael A Pagel; CI McCormick; S Guitjens; Leslie L Muldoon
In vitro and animal studies of sodium thiosulfate as a potential chemoprotectant against carboplatin-induced ototoxicity.
Cancer research 1996;56(4):706-9.
1995: Leslie L Muldoon; G Nilaver; RA Kroll; Michael A Pagel; X O Breakefield; E A Chiocca; B L Davidson; R Weissleder; Edward A Neuwelt
Comparison of intracerebral inoculation and osmotic blood-brain barrier disruption for delivery of adenovirus, herpesvirus, and iron oxide particles to normal rat brain.
The American journal of pathology 1995;147(6):1840-51.
1995: G Nilaver; Leslie L Muldoon; RA Kroll; Michael A Pagel; X O Breakefield; B L Davidson; Edward A Neuwelt
Delivery of herpesvirus and adenovirus to nude rat intracerebral tumors after osmotic blood-brain barrier disruption.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(21):9829-33.
1995: LG Remsen; CI McCormick; Gary Sexton; H D Pearse; R Garcia; Edward A Neuwelt
Decreased delivery and acute toxicity of cranial irradiation and chemotherapy given with osmotic blood-brain barrier disruption in a rodent model: the issue of sequence.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(7):731-9.
1995: P C Williams; W D Henner; SM Roman-Goldstein; S A Dahlborg; R E Brummett; M Tableman; B W Dana; Edward A Neuwelt
Toxicity and efficacy of carboplatin and etoposide in conjunction with disruption of the blood-brain tumor barrier in the treatment of intracranial neoplasms.
Neurosurgery 1995;37(1):17-27; discussion 27-8.
1995: RA Kroll; Michael A Pagel; SM Roman-Goldstein; A J Barkovich; A N D'Agostino; Edward A Neuwelt
White matter changes associated with feline GM2 gangliosidosis (Sandhoff disease): correlation of MR findings with pathologic and ultrastructural abnormalities.
AJNR. American journal of neuroradiology 1995;16(6):1219-26.
1995: S E Doran; X D Ren; AL Betz; M A Pagel; Edward A Neuwelt; Blake J Roessler; Beverly L Davidson
Gene expression from recombinant viral vectors in the central nervous system after blood-brain barrier disruption.
Neurosurgery 1995;36(5):965-70.
1995: SM Roman-Goldstein; Peter Mitchell; John Robert (Jack) Crossen; P C Williams; A Tindall; Edward A Neuwelt
MR and cognitive testing of patients undergoing osmotic blood-brain barrier disruption with intraarterial chemotherapy.
AJNR. American journal of neuroradiology 1995;16(3):543-53.
1995: P A Barnett; SM Roman-Goldstein; F Ramsey; CI McCormick; Gary Sexton; Jerzy (Urick) Szumowski; Edward A Neuwelt
Differential permeability and quantitative MR imaging of a human lung carcinoma brain xenograft in the nude rat.
The American journal of pathology 1995;146(2):436-49.
1994: RA Kroll; Michael A Pagel; J J Langone; Gary Sexton; Edward A Neuwelt
Differential permeability of the blood-tumour barrier in intracerebral tumour-bearing rats: antidrug antibody to achieve systemic drug rescue.
Therapeutic immunology 1994;1(6):333-41.
1994: Edward A Neuwelt; P A Barnett; K E Hellström; I Hellström; CI McCormick; F L Ramsey
Effect of blood-brain barrier disruption on intact and fragmented monoclonal antibody localization in intracerebral lung carcinoma xenografts.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1994;35(11):1831-41.
1994: SM Roman-Goldstein; P A Barnett; CI McCormick; Jerzy (Urick) Szumowski; E M Shannon; F L Ramsey; Michele K Mass; Edward A Neuwelt
Effects of Gd-DTPA after osmotic BBB disruption in a rodent model: toxicity and MR findings.
Journal of computer assisted tomography 1994;18(5):731-6.
1994: Leslie L Muldoon; Edward A Neuwelt; Michael A Pagel; D L Weiss
Characterization of the molecular defect in a feline model for type II GM2-gangliosidosis (Sandhoff disease).
The American journal of pathology 1994;144(5):1109-18.
1994: Edward A Neuwelt; R Weissleder; G Nilaver; RA Kroll; SM Roman-Goldstein; Jerzy (Urick) Szumowski; Michael A Pagel; R S Jones; LG Remsen; CI McCormick
Delivery of virus-sized iron oxide particles to rodent CNS neurons.
Neurosurgery 1994;34(4):777-84.
1994: SM Roman-Goldstein; D A Clunie; Jeffrey S Stevens; R Hogan; J Monard; F Ramsey; Edward A Neuwelt
Osmotic blood-brain barrier disruption: CT and radionuclide imaging.
AJNR. American journal of neuroradiology 1994;15(3):581-90.
1994: John Robert (Jack) Crossen; D Garwood; E Glatstein; Edward A Neuwelt
Neurobehavioral sequelae of cranial irradiation in adults: a review of radiation-induced encephalopathy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1994;12(3):627-42.
1994: Edward A Neuwelt; P C Wiliams; B E Mickey; E P Frenkel; W D Henner
Therapeutic dilemma of disseminated CNS germinoma and the potential of increased platinum-based chemotherapy delivery with osmotic blood-brain barrier disruption.
Pediatric neurosurgery 1994;21(1):16-22.
1993: Edward A Neuwelt; P A Barnett; F L Ramsey; I Hellström; K E Hellström; CI McCormick
Dexamethasone decreases the delivery of tumor-specific monoclonal antibody to both intracerebral and subcutaneous tumor xenografts.
Neurosurgery 1993;33(3):478-84; discussion 484.
1993: J A Williams; SM Roman-Goldstein; John Robert (Jack) Crossen; A D'Agostino; S A Dahlborg; Edward A Neuwelt
Preirradiation osmotic blood-brain barrier disruption plus combination chemotherapy in gliomas: quantitation of tumor response to assess chemosensitivity.
Advances in experimental medicine and biology 1993;331():273-84.
1993: M K Gumerlock; Edward A Neuwelt
Primary cerebral lymphoma.
Cancer treatment and research 1993;66():111-26.
1992: J M Nazzaro; Michael A Pagel; Edward A Neuwelt
Further refinement of the Escherichia coli brain abscess model in rat.
Journal of neuroscience methods 1992;44(2-3):85-90.
1992: A E Avolio; F L Ramsey; Edward A Neuwelt
Evaluation of a program to prevent head and spinal cord injuries: a comparison between middle school and high school.
Neurosurgery 1992;31(3):557-61; discussion 561-2.
1992: SM Roman-Goldstein; D L Goldman; J Howieson; R Belkin; Edward A Neuwelt
MR of primary CNS lymphoma in immunologically normal patients.
AJNR. American journal of neuroradiology 1992;13(4):1207-13.
1992: J M Nazzaro; W T Shults; Edward A Neuwelt
Neuro-ophthalmological function of patients with pineal region tumors approached transtentorially in the semisitting position.
Journal of neurosurgery 1992;76(5):746-51.
1992: John Robert (Jack) Crossen; D L Goldman; S A Dahlborg; Edward A Neuwelt
Neuropsychological assessment outcomes of nonacquired immunodeficiency syndrome patients with primary central nervous system lymphoma before and after blood-brain barrier disruption chemotherapy.
Neurosurgery 1992;30(1):23-9.
1991: SM Roman-Goldstein; P A Barnett; CI McCormick; Melvyn Ball; F Ramsey; Edward A Neuwelt
Effects of gadopentetate dimeglumine administration after osmotic blood-brain barrier disruption: toxicity and MR imaging findings.
AJNR. American journal of neuroradiology 1991;12(5):885-90.
1991: Edward A Neuwelt; D L Goldman; S A Dahlborg; John Robert (Jack) Crossen; F Ramsey; SM Roman-Goldstein; Rita M Braziel; B Dana
Primary CNS lymphoma treated with osmotic blood-brain barrier disruption: prolonged survival and preservation of cognitive function.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1991;9(9):1580-90.
1991: J M Nazzaro; L C Rosenbaum; Michael A Pagel; Edward A Neuwelt
A new model of systemic drug rescue based on permeability characteristics of the blood-brain barrier in intracerebral abscess-bearing rats.
Journal of neurosurgery 1991;74(3):467-74.
1991: Edward A Neuwelt; Michael A Pagel; Richard Dix
Delivery of ultraviolet-inactivated 35S-herpesvirus across an osmotically modified blood-brain barrier.
Journal of neurosurgery 1991;74(3):475-9.
1990: L C Rosenbaum; Edward A Neuwelt; Hubert H M Van Tol; Y P Loh; Joseph G Verbalis; I Hellström; K E Hellström; G Nilaver
Expression of neurophysin-related precursor in cell membranes of a small-cell lung carcinoma.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(24):9928-32.
1990: G Nilaver; L C Rosenbaum; Hubert H M Van Tol; E M Shannon; H M Hagman; E A Zimmerman; Edward A Neuwelt
Immunological studies with a monoclonal antibody suggest a different conformation of neurophysin in parvicellular neurons of rat hypothalamus.
Brain research 1990;529(1-2):302-8.
1990: J M Nazzaro; Edward A Neuwelt
The role of surgery in the management of supratentorial intermediate and high-grade astrocytomas in adults.
Journal of neurosurgery 1990;73(3):331-44.
1990: G Nilaver; L C Rosenbaum; K E Hellström; I Hellström; Edward A Neuwelt
Identification of neurophysin immunoreactivity in hypothalamus by a monoclonal antibody to a carcinoma cell surface antigen.
Neuroendocrinology 1990;51(5):565-71.
1990: M K Gumerlock; Edward A Neuwelt
The effects of anesthesia on osmotic blood-brain barrier disruption.
Neurosurgery 1990;26(2):268-77.
1990: Edward A Neuwelt; J M Nazzaro; M K Gumerlock
Is there a role for biopsy in the treatment of supratentorial high-grade glioma?
Clinical neurosurgery 1990;36():384-407.
1990: Edward A Neuwelt; A Horaczek; M A Pagel
The effect of steroids on gentamicin delivery to brain after blood-brain barrier disruption.
Journal of neurosurgery 1990;72(1):123-6.
1989: L C Rosenbaum; G Nilaver; H M Hagman; Edward A Neuwelt
Detection of low-molecular-weight polypeptides on nitrocellulose with monoclonal antibodies.
Analytical biochemistry 1989;183(2):250-7.
1989: Richard A Yeager; Gregory L Moneta; Donald B McConnell; Edward A Neuwelt; Lloyd M Taylor; J M Porter
Analysis of risk factors for myocardial infarction following carotid endarterectomy.
Archives of surgery (Chicago, Ill. : 1960) 1989;124(10):1142-5.
1989: Edward A Neuwelt
Radiotherapy for tumours of the pineal region and suprasellar germinomas (by Glanzmann and Seelentag)
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 1989;16(1):79-80.
1989: G Nilaver; L C Rosenbaum; K Fukui; Edward A Neuwelt; W K Samson; E A Zimmerman; D M Gibbs
An antiserum to atrial natriuretic factor (ANF) cross-reacts with neurophysins in the hypothalamo-neurohypophysial system of rat brain.
Neuropeptides 1989;14(2):137-44.
1989: Edward A Neuwelt; M F Coe; A M Wilkinson; A E Avolio
Oregon Head and Spinal Cord Injury Prevention Program and evaluation.
Neurosurgery 1989;24(3):453-8.
1988: M K Gumerlock; Edward A Neuwelt
Carotid endarterectomy: to shunt or not to shunt.
Stroke; a journal of cerebral circulation 1988;19(12):1485-90.
1988: Edward A Neuwelt; P A Barnett; I Hellström; K E Hellström; P Beaumier; CI McCormick; R M Weigel
Delivery of melanoma-associated immunoglobulin monoclonal antibody and Fab fragments to normal brain utilizing osmotic blood-brain barrier disruption.
Cancer research 1988;48(17):4725-9.
1987: S Goldstein; M K Gumerlock; Edward A Neuwelt
Comparison of CT-guided and stereotaxic cranial diagnostic needle biopsies.
Journal of neurosurgery 1987;67(3):341-8.
1987: Edward A Neuwelt; H D Specht; P A Barnett; S A Dahlborg; A Miley; Steven M Larson; P Brown; K F Eckerman; K E Hellström; I Hellström
Increased delivery of tumor-specific monoclonal antibodies to brain after osmotic blood-brain barrier modification in patients with melanoma metastatic to the central nervous system.
Neurosurgery 1987;20(6):885-95.
1987: S Goldstein; Edward A Neuwelt
Superior sensitivity of computed tomographic scanning to magnetic resonance imaging in metastatic neoplasia: two case reports.
Neurosurgery 1987;20(6):959-62.
1987: Edward A Neuwelt; S A Dahlborg
Chemotherapy administered in conjunction with osmotic blood-brain barrier modification in patients with brain metastases.
Journal of neuro-oncology 1987;4(3):195-207.
1986: R H Millay; Michael L Klein; W T Shults; S A Dahlborg; Edward A Neuwelt
Maculopathy associated with combination chemotherapy and osmotic opening of the blood-brain barrier.
American journal of ophthalmology 1986;102(5):626-32.
1986: Edward A Neuwelt; E P Frenkel; M K Gumerlock; Rita M Braziel; B Dana; S A Hill
Developments in the diagnosis and treatment of primary CNS lymphoma. A prospective series.
Cancer 1986;58(8):1609-20.
1986: Edward A Neuwelt; J Howieson; E P Frenkel; H D Specht; R Weigel; C G Buchan; S A Hill
Therapeutic efficacy of multiagent chemotherapy with drug delivery enhancement by blood-brain barrier modification in glioblastoma.
Neurosurgery 1986;19(4):573-82.
1986: Edward A Neuwelt; H D Specht; S A Hill
Permeability of human brain tumor to 99mTc-gluco-heptonate and 99mTc-albumin. Implications for monoclonal antibody therapy.
Journal of neurosurgery 1986;65(2):194-8.
1986: Edward A Neuwelt; S A Hill
Neurosurgery: chemotherapy in conjunction with blood-brain barrier modification in patients with cerebral metastasis.
The Western journal of medicine 1986;145(1):86.
1986: Edward A Neuwelt; J Minna; E Frenkel; P A Barnett; CI McCormick
Osmotic blood-brain barrier opening to IgM monoclonal antibody in the rat.
The American journal of physiology 1986;250(5 Pt 2):R875-83.
1986: Edward A Neuwelt; B Mickey; Alfred J Lewy
The importance of melatonin and tumor markers in pineal tumors.
Journal of neural transmission. Supplementum 1986;21():397-413.
1985: Edward A Neuwelt; P A Barnett; CI McCormick; E P Frenkel; J D Minna
Osmotic blood-brain barrier modification: monoclonal antibody, albumin, and methotrexate delivery to cerebrospinal fluid and brain.
Neurosurgery 1985;17(3):419-23.
1985: Edward A Neuwelt; W G Johnson; N K Blank; M A Pagel; C Maslen-McClure; M J McClure; P M Wu
Characterization of a new model of GM2-gangliosidosis (Sandhoff's disease) in Korat cats.
The Journal of clinical investigation 1985;76(2):482-90.
1985: Edward A Neuwelt; E P Frenkel; A N D'Agostino; D N Carney; J D Minna; P A Barnett; CI McCormick
Growth of human lung tumor in the brain of the nude rat as a model to evaluate antitumor agent delivery across the blood-brain barrier.
Cancer research 1985;45(6):2827-33.
1985: M K Gumerlock; B M Coull; J Howieson; C Buchan; Edward A Neuwelt
Late stenosis of a superficial temporal-middle cerebral artery bypass: angiographic and histological findings.
Neurosurgery 1985;16(5):650-7.
1985: Edward A Neuwelt; C Buchan; N K Blank; Alfred J Lewy
Surgical resection of a pineal tumor containing elements of germinoma and astrocytoma.
Neurosurgery 1985;16(3):373-8.
1985: M Ohata; W R Fredericks; Edward A Neuwelt; U Sundaram; Stanley I Rapoport
[3H]Methotrexate loss from the rat brain following enhanced uptake by osmotic opening of the blood-brain barrier.
Cancer research 1985;45(3):1092-6.
1985: Edward A Neuwelt
An update on the surgical treatment of malignant pineal region tumors.
Clinical neurosurgery 1985;32():397-428.
1984: K Kikuchi; C I McCormick; Edward A Neuwelt
Immunosuppression by phenytoin: implication for altered immune competence in brain-tumor patients.
Journal of neurosurgery 1984;61(6):1085-90.
1984: Edward A Neuwelt; M S Lawrence; N K Blank
Effect of gentamicin and dexamethasone on the natural history of the rat Escherichia coli brain abscess model with histopathological correlation.
Neurosurgery 1984;15(4):475-83.
1984: Edward A Neuwelt; D E Baker; M A Pagel; N K Blank
Cerebrovascular permeability and delivery of gentamicin to normal brain and experimental brain abscess in rats.
Journal of neurosurgery 1984;61(3):430-9.
1984: Edward A Neuwelt; S A Hill; E P Frenkel
Osmotic blood-brain barrier modification and combination chemotherapy: concurrent tumor regression in areas of barrier opening and progression in brain regions distant to barrier opening.
Neurosurgery 1984;15(3):362-6.
1984: Edward A Neuwelt; J A Barranger; M A Pagel; J M Quirk; R O Brady; E P Frenkel
Delivery of active hexosaminidase across the blood-brain barrier in rats.
Neurology 1984;34(8):1012-9.
1984: Edward A Neuwelt; Stanley I Rapoport
Modification of the blood-brain barrier in the chemotherapy of malignant brain tumors.
Federation proceedings 1984;43(2):214-9.
1984: Edward A Neuwelt; P A Barnett; E P Frenkel
Chemotherapeutic agent permeability to normal brain and delivery to avian sarcoma virus-induced brain tumors in the rodent: observations on problems of drug delivery.
Neurosurgery 1984;14(2):154-60.
1984: Edward A Neuwelt
Therapeutic potential for blood-brain barrier modification in malignant brain tumor.
Progress in experimental tumor research 1984;28():51-66.
1983: K Kikuchi; Edward A Neuwelt
Presence of immunosuppressive factors in brain-tumor cyst fluid.
Journal of neurosurgery 1983;59(5):790-9.
1983: Edward A Neuwelt; P A Barnett; M Glasberg; E P Frenkel
Pharmacology and neurotoxicity of cis-diamminedichloroplatinum, bleomycin, 5-fluorouracil, and cyclophosphamide administration following osmotic blood-brain barrier modification.
Cancer research 1983;43(11):5278-85.
1983: Edward A Neuwelt; H D Specht; J Howieson; J E Haines; M J Bennett; S A Hill; E P Frenkel
Osmotic blood-brain barrier modification: clinical documentation by enhanced CT scanning and/or radionuclide brain scanning.
AJR. American journal of roentgenology 1983;141(4):829-35.
1983: Edward A Neuwelt; M Glasberg; E Frenkel; P Barnett
Neurotoxicity of chemotherapeutic agents after blood-brain barrier modification: neuropathological studies.
Annals of neurology 1983;14(3):316-24.
1983: Edward A Neuwelt; E Balaban; J Diehl; S Hill; E Frenkel
Successful treatment of primary central nervous system lymphomas with chemotherapy after osmotic blood-brain barrier opening.
Neurosurgery 1983;12(6):662-71.
1983: Edward A Neuwelt; Alfred J Lewy
Disappearance of plasma melatonin after removal of a neoplastic pineal gland.
The New England journal of medicine 1983;308(19):1132-5.
1983: M K Gumerlock; H Ono; Edward A Neuwelt
Can a patent extracranial-intracranial bypass provoke the conversion of an intracranial arterial stenosis to a symptomatic occlusion?
Neurosurgery 1983;12(4):391-400.
1983: Edward A Neuwelt; K Kikuchi; S Hill; P Lipsky; E P Frenkel
Immune responses in patients with brain tumors. Factors such as anti-convulsants that may contribute to impaired cell-mediated immunity.
Cancer 1983;51(2):248-55.
1983: Edward A Neuwelt; S A Hill; K Kikuchi
Malignant and benign brain tumors: current concepts and intervention.
Comprehensive therapy 1983;9(1):24-32.
1983: Edward A Neuwelt; P Barnett; J Barranger; C McCormick; M Pagel; E Frenkel
Inability of dimethyl sulfoxide and 5-fluorouracil to open the blood-brain barrier.
Neurosurgery 1983;12(1):29-34.
1982: N Kandalaft; J Diehl; Edward A Neuwelt
Nonneoplastic intracranial lesions simulating neoplasms on computed tomographic scan. Excellent sensitivity with limited specificity.
JAMA : the journal of the American Medical Association 1982;248(17):2166-8.
1982: Edward A Neuwelt; P A Barnett; D D Bigner; E P Frenkel
Effects of adrenal cortical steroids and osmotic blood-brain barrier opening on methotrexate delivery to gliomas in the rodent: the factor of the blood-brain barrier.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(14):4420-3.
1982: S A Hill; Edward A Neuwelt
Intra-arterial chemotherapy following blood-brain barrier disruption in a patient with malignant glioma.
Journal of neurosurgical nursing 1982;14(2):94-7.
1982: S W Watson; D P Sinn; Edward A Neuwelt
Dental considerations in the sublabial trans-sphenoidal surgical approach to the pituitary gland.
Neurosurgery 1982;10(2):236-41.
1982: Edward A Neuwelt; K Kikuchi; S A Hill; P Lipsky; E Frenkel
Barbiturate inhibition of lymphocyte function. Differing effects of various barbiturates used to induce coma.
Journal of neurosurgery 1982;56(2):254-9.
1981: Edward A Neuwelt; M Glasberg; J Diehl; E P Frenkel; P Barnett
Osmotic blood-brain barrier disruption in the posterior fossa of the dog.
Journal of neurosurgery 1981;55(5):742-8.
1981: Edward A Neuwelt; M Pagel; P Barnett; Marilyn Glassberg Csete; E P Frenkel
Pharmacology and toxicity of intracarotid adriamycin administration following osmotic blood-brain barrier modification.
Cancer research 1981;41(11 Pt 1):4466-70.
1981: Edward A Neuwelt; J A Barranger; R O Brady; M Pagel; F S Furbish; J M Quirk; G E Mook; E Frenkel
Delivery of hexosaminidase A to the cerebrum after osmotic modification of the blood--brain barrier.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(9):5838-41.
1981: Edward A Neuwelt; J T Diehl; L H Vu; S A Hill; A J Michael; E P Frenkel
Monitoring of methotrexate delivery in patients with malignant brain tumors after osmotic blood-brain barrier disruption.
Annals of internal medicine 1981;94(4 pt 1):449-54.
1981: Edward A Neuwelt
CT monitoring of chemotherapeutic agent delivery after osmotic blood brain barrier disruption.
Clinical neurosurgery 1981;28():520-31.
1981: Edward A Neuwelt; S A Hill; E P Frenkel; J T Diehl; K R Maravilla; L H Vu; W K Clark; Stanley I Rapoport; P A Barnett; S E Lewis; A L Ehle; C W Beyer
Osmotic blood-brain barrier disruption: pharmacodynamic studies in dogs and a clinical phase I trial in patients with malignant brain tumors.
Cancer treatment reports 1981;65 Suppl 2():39-43.
1981: Edward A Neuwelt
Use of antibodies and the primary enzyme immunoassay (PEIA) to study enzymes: the arylsulfatase A--anti-arylsulfatase A system.
Methods in enzymology 1981;73(Pt B):550-78.
1980: Edward A Neuwelt; E P Frenkel; R G Smith
Suprasellar germinomas (ectopic pinealomas): aspects of immunological characterization and successful chemotherapeutic responses in recurrent disease.
Neurosurgery 1980;7(4):352-8.
1980: Edward A Neuwelt
Reversible osmotic blood-brain barrier disruption in humans: implications for the chemotherapy of malignant brain tumors.
Neurosurgery 1980;7(2):204.
1980: Edward A Neuwelt; E P Frenkel; Stanley I Rapoport; P Barnett
Effect of osmotic blood-brain barrier disruption on methotrexate pharmacokinetics in the dog.
Neurosurgery 1980;7(1):36-43.
1980: Edward A Neuwelt; E P Frenkel
Is there a therapeutic role for blood-brain barrier disruption?
Annals of internal medicine 1980;93(1):137-9.
1980: Edward A Neuwelt; E P Frenkel; J Diehl; L H Vu; Stanley I Rapoport; S Hill
Reversible osmotic blood-brain barrier disruption in humans: implications for the chemotherapy of malignant brain tumors.
Neurosurgery 1980;7(1):44-52.
1980: D S Samson; Edward A Neuwelt; C W Beyer; Q M Ditmore
Failure of extracranial-intracranial arterial bypass in acute middle cerebral artery occlusion: case report.
Neurosurgery 1980;6(2):185-8.
1980: Edward A Neuwelt; K R Maravilla; E P Frenkel; P Barnett; S Hill; R J Moore
Use of enhanced computerized tomography to evaluate osmotic blood-brain barrier disruption.
Neurosurgery 1980;6(1):49-56.
1979: Edward A Neuwelt; M Glasberg; E Frenkel; W K Clark
Malignant pineal region tumors. A clinico-pathological study.
Journal of neurosurgery 1979;51(5):597-607.
1979: Edward A Neuwelt; J T Diehl; S A Hill; K R Maravilla
Use of metrizamide computerized tomographic cisternography in the evaluation of patients with malignant glioma for immunotherapy.
Neurosurgery 1979;5(5):576-82.
1979: K R Maravilla; Edward A Neuwelt; J T Diehl
Application of metrizamide in the radiographic evaluation of the neurologically diseased patient.
Neurosurgery 1979;5(3):389-406.
1979: Edward A Neuwelt; K R Maravilla; E P Frenkel; S I Rapaport; S A Hill; P A Barnett
Osmotic blood-brain barrier disruption. Computerized tomographic monitoring of chemotherapeutic agent delivery.
The Journal of clinical investigation 1979;64(2):684-8.
1979: Edward A Neuwelt; R G Smith
Presence of lymphocyte membrane surface markers on "small cells" in a pineal germinoma.
Annals of neurology 1979;6(2):133-6.
1979: Edward A Neuwelt; E P Frenkel; J T Diehl; K R Maravilla; L H Vu; W K Clark; Stanley I Rapoport; P A Barnett; S A Hill; S E Lewis; A L Ehle; C W Beyer; R J Moore
Osmotic blood-brain barrier disruption: a new means of increasing chemotherapeutic agent delivery.
Transactions of the American Neurological Association 1979;104():256-60.
1978: Edward A Neuwelt; W K Clark
Unique aspects of central nervous system immunology.
Neurosurgery 1978;3(3):419-30.
1978: Edward A Neuwelt; K Clark; J B Kirkpatrick; H Toben
Clinical studies of intrathecal autologous lymphocyte infusions in patients with malignant glioma: a toxicity study.
Annals of neurology 1978;4(4):307-12.
1978: Edward A Neuwelt; JH Garcia; H Mena
Diffuse microglial proliferation after global ischemia in a patient with aplastic bone marrow.
Acta neuropathologica 1978;43(3):259-62.
1978: Edward A Neuwelt; M S Boguski; J J Frank; K Procter-Appich; C C Levy
Possible sites of origin of human plasma ribonucleases as evidenced by isolation and partial characterization of ribonucleases from several human tissues.
Cancer research 1978;38(1):88-93.
1977: Edward A Neuwelt; D Doherty
Toxicity kinetics and clinical potential of subarachnoid lymphocyte infusions.
Journal of neurosurgery 1977;47(2):205-17.
1977: Edward A Neuwelt; JH Garcia; O Kolar; K Rao; Thomas B Ducker
Elevated CSF gamma globulins with cerebral "glioma.".
Surgical neurology 1977;8(2):107-10.
1977: RICHARD HUMPHREY; T P Karpetsky; Edward A Neuwelt; C C Levy
Levels of serum ribonuclease as an indicator of renal insufficiency in patients with leukemia.
Cancer research 1977;37(7 Pt 1):2015-22.
1977: Edward A Neuwelt; M Schmukler; M S Niziak; P B Jewett; C C Levy
The immunological characterization of several human ribonucleases by using primary binding tests.
The Biochemical journal 1977;163(3):419-26.
1977: Roger Rosenberg; Edward A Neuwelt; J Kirkpatrick; P Kohler
Encephalopathy associated with cryoprecipitable Australia antigen.
Annals of neurology 1977;1(3):298-300.
1976: Edward A Neuwelt; William A Gahl; C C Levy
Immunological studies on the interaction of polyadenylic acid and human liver ribonuclease.
Biochemical and biophysical research communications 1976;73(4):885-93.
1976: Edward A Neuwelt; J J Frank; C C Levy
Purification of human spleen ribonuclease by immunoabsorption. Similarity of the enzyme with human liver ribonuclease.
The Journal of biological chemistry 1976;251(18):5752-8.
1973: Edward A Neuwelt; P F Kohler; J Austin
Primary enzyme immunoassay (PEIA): studies of the mutant enzyme in metachromatic leukodystrophy (primary enzyme immunoassay of arylsulfatase-A).
Immunochemistry 1973;10(11):767-73.
1971: D Stumpf; Edward A Neuwelt; J Austin; P Kohler
Metachromatic leukodystrophy (MLD). X. Immunological studies of the abnormal sulfatase A.
Archives of neurology 1971;25(5):427-31.
1971: Edward A Neuwelt; D Stumpf; J Austin; P Kohler
A monospecific antibody to human sulfatase A. Preparation, characterization and significance.
Biochimica et biophysica acta 1971;236(1):333-46.
1971: D Stumpf; Edward A Neuwelt; J Austin; P Kohler
Immunological studies of sulfatase A in normals and in metachromatic leukodystrophy.
Transactions of the American Neurological Association 1971;96():80-3.