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Joseph Nevins

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TOP 3
S P Angus; Joseph R Nevins
A role for Mediator complex subunit MED13L in Rb/E2F-induced growth arrest.
J Y Leung; Eran R Andrechek; Robert Cardiff; Joseph R Nevins
Heterogeneity in MYC-induced mammary tumors contributes to escape from oncogene dependence.
Chaitanya R Acharya; Carey K Anders; Ariel Anguiano; William T Barry; Holly K Dressman; Katherine S Garman; Geoffrey S Ginsburg; David S Hsu; Gary H Lyman; Kelly P Marcom; Cynthia A Moylan; Sayan Mukherjee; Joseph R Nevins; Richard C Redman; Kelly H Salter; Sascha A Tuchman; Kelli S Walters; Anil Potti
Retraction: Acharya CR, et al. Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer. JAMA. 2008;299(13):1574-1587.

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2012: S P Angus; Joseph R Nevins
A role for Mediator complex subunit MED13L in Rb/E2F-induced growth arrest.
Oncogene 2012;31(44):4709-17.
2012: J Y Leung; Eran R Andrechek; Robert Cardiff; Joseph R Nevins
Heterogeneity in MYC-induced mammary tumors contributes to escape from oncogene dependence.
Oncogene 2012;31(20):2545-54.
2012: Chaitanya R Acharya; Carey K Anders; Ariel Anguiano; William T Barry; Holly K Dressman; Katherine S Garman; Geoffrey S Ginsburg; David S Hsu; Gary H Lyman; Kelly P Marcom; Cynthia A Moylan; Sayan Mukherjee; Joseph R Nevins; Richard C Redman; Kelly H Salter; Sascha A Tuchman; Kelli S Walters; Anil Potti
Retraction: Acharya CR, et al. Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer. JAMA. 2008;299(13):1574-1587.
JAMA : the journal of the American Medical Association 2012;307(5):453.
2011: Jeffrey V Wong; Peng Dong; Bernard Mathey-Prevot; Joseph R Nevins; Lingchong You
Network calisthenics: control of E2F dynamics in cell cycle entry.
Cell cycle (Georgetown, Tex.) 2011;10(18):3086-94.
2011: Jennifer A Freedman; Douglas S Tyler; Joseph R Nevins; Christina K Augustine
Use of gene expression and pathway signatures to characterize the complexity of human melanoma.
The American journal of pathology 2011;178(6):2513-22.
2011: Joseph R Nevins
Pathway-based classification of lung cancer: a strategy to guide therapeutic selection.
Proceedings of the American Thoracic Society 2011;8(2):180-2.
2011: Guang Yao; Cheemeng Tan; Mike West; Joseph R Nevins; Lingchong You
Origin of bistability underlying mammalian cell cycle entry.
Molecular systems biology 2011;7():485.
2011: Igor Shats; Michael L Gatza; Jeffrey T Chang; Seiichi Mori; Jialiang Wang; Jeremy Rich; Joseph R Nevins
Using a stem cell-based signature to guide therapeutic selection in cancer.
Cancer research 2011;71(5):1772-80.
2011: Jeffrey V Wong; Guang Yao; Joseph R Nevins; Lingchong You
Viral-mediated noisy gene expression reveals biphasic E2f1 response to MYC.
Molecular cell 2011;41(3):275-85.
2011: Heather G LaBreche; Sarah K Meadows; Joseph R Nevins; John P Chute
Peripheral blood signatures of lead exposure.
PloS one 2011;6(8):e23043.
2011: Heather G LaBreche; Joseph R Nevins; Erich Huang
Integrating factor analysis and a transgenic mouse model to reveal a peripheral blood predictor of breast tumors.
BMC medical genomics 2011;4():61.
2011: Jeffrey V Wong; Guang Yao; Joseph R Nevins; Lingchong You
Using noisy gene expression mediated by engineered adenovirus to probe signaling dynamics in mammalian cells.
Methods in enzymology 2011;497():221-37.
2010: Eran R Andrechek; Joseph R Nevins
Mouse models of cancers: opportunities to address heterogeneity of human cancer and evaluate therapeutic strategies.
Journal of molecular medicine (Berlin, Germany) 2010;88(11):1095-100.
2010: William T Barry; Dawn N Kernagis; Holly K Dressman; Ryan J Griffis; J'vonne D Hunter; John Olson; Jeffrey R Marks; Geoffrey S Ginsburg; Paul Kelly Marcom; Joseph R Nevins; Joseph Geradts; Michael B Datto
Intratumor heterogeneity and precision of microarray-based predictors of breast cancer biology and clinical outcome.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(13):2198-206.
2010: Michael L Gatza; Joseph E Lucas; William T Barry; Jong Wook Kim; Quanli Wang; Matthew D Crawford; Michael B Datto; Michael Kelley; Bernard Mathey-Prevot; Anil Potti; Joseph R Nevins
A pathway-based classification of human breast cancer.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(15):6994-9.
2010: Hilary E Wade; Sakiko Kobayashi; Matthew L Eaton; Michelle S Jansen; Edward K Lobenhofer; Mathieu Lupien; Timothy R Geistlinger; Wencheng Zhu; Joseph R Nevins; Myles Brown; Deborah C Otteson; Donald P McDonnell
Multimodal regulation of E2F1 gene expression by progestins.
Molecular and cellular biology 2010;30(8):1866-77.
2010: Tae J Lee; Guang Yao; Dorothy C Bennett; Joseph R Nevins; Lingchong You
Stochastic E2F activation and reconciliation of phenomenological cell-cycle models.
PLoS biology 2010;8(9):.
2010: Sarah K Meadows; Holly K Dressman; Pamela Daher; Heather Himburg; J Lauren Russell; Phuong Doan; Nelson J Chao; Joseph Lucas; Joseph R Nevins; John P Chute
Diagnosis of partial body radiation exposure in mice using peripheral blood gene expression profiles.
PloS one 2010;5(7):e11535.
2009: Christopher L Tebbit; Jun Zhai; Brian R Untch; Matthew J Ellis; Holly K Dressman; Rex C Bentley; Jay A Baker; Paul Kelly Marcom; Joseph R Nevins; Jeffrey R Marks; John Olson
Novel tumor sampling strategies to enable microarray gene expression signatures in breast cancer: a study to determine feasibility and reproducibility in the context of clinical care.
Breast cancer research and treatment 2009;118(3):635-43.
2009: Eran R Andrechek; Robert Cardiff; Jeffrey T Chang; Michael L Gatza; Chaitanya R Acharya; Anil Potti; Joseph R Nevins
Genetic heterogeneity of Myc-induced mammary tumors reflecting diverse phenotypes including metastatic potential.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(38):16387-92.
2009: Rachel E Rempel; Seiichi Mori; Maura Gasparetto; Michele A Glozak; Eran R Andrechek; Steven B Adler; Nina M Laakso; Anand S Lagoo; Robert Storms; Clay Smith; Joseph R Nevins
A role for E2F activities in determining the fate of Myc-induced lymphomagenesis.
PLoS genetics 2009;5(9):e1000640.
2009: Ariel Anguiano; Sascha A Tuchman; Chaitanya R Acharya; Kelly Salter; Cristina Gasparetto; Fenghuang Zhan; Madhav Dhodapkar; Joseph R Nevins; Bart Barlogie; John D Shaughnessy; Anil Potti
Gene expression profiles of tumor biology provide a novel approach to prognosis and may guide the selection of therapeutic targets in multiple myeloma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(25):4197-203.
2009: J A Freedman; Jeffrey T Chang; L Jakoi; Joseph R Nevins
A combinatorial mechanism for determining the specificity of E2F activation and repression.
Oncogene 2009;28(32):2873-81.
2009: Susumu Mori; Jeffrey T Chang; Eran R Andrechek; N Matsumura; T Baba; G Yao; J W Kim; M Gatza; S Murphy; Joseph R Nevins
Anchorage-independent cell growth signature identifies tumors with metastatic potential.
Oncogene 2009;28(31):2796-805.
2009: Jeffrey T Chang; Carlos Carvalho; Seiichi Mori; Andrea Bild; Michael L Gatza; Quanli Wang; Joseph E Lucas; Anil Potti; Phillip G Febbo; Mike West; Joseph R Nevins
A genomic strategy to elucidate modules of oncogenic pathway signaling networks.
Molecular cell 2009;34(1):104-14.
2009: David S Hsu; Chaitanya R Acharya; Bala S Balakumaran; Richard F Riedel; Mickey K Kim; Marvaretta Stevenson; Sascha Tuchman; Sayan Mukherjee; William Barry; Holly K Dressman; Joseph R Nevins; Scott Powers; David Mu; Anil Potti
Characterizing the developmental pathways TTF-1, NKX2-8, and PAX9 in lung cancer.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(13):5312-7.
2009: Timothy C Hallstrom; Joseph R Nevins
Balancing the decision of cell proliferation and cell fate.
Cell cycle (Georgetown, Tex.) 2009;8(4):532-5.
2009: Seiichi Mori; Jeffrey T Chang; Eran R Andrechek; Anil Potti; Joseph R Nevins
Utilization of genomic signatures to identify phenotype-specific drugs.
PloS one 2009;4(8):e6772.
2008: Katherine S Garman; Chaitanya R Acharya; Elena Edelman; Marian Grade; Jochen Gaedcke; Shivani Sud; William Barry; Anna Mae Diehl; Dawn Provenzale; Geoffrey S Ginsburg; B Michael Ghadimi; Thomas Ried; Joseph R Nevins; Sayan Mukherjee; David Hsu; Anil Potti
A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(49):19432-7.
2008: Seiichi Mori; Rachel E Rempel; Jeffrey T Chang; Guang Yao; Anand S Lagoo; Anil Potti; Andrea Bild; Joseph R Nevins
Utilization of pathway signatures to reveal distinct types of B lymphoma in the Emicro-myc model and human diffuse large B-cell lymphoma.
Cancer research 2008;68(20):8525-34.
2008: Ariel Anguiano; Joseph R Nevins; Anil Potti
Toward the individualization of lung cancer therapy.
Cancer 2008;113(7 Suppl):1760-7.
2008: Eran R Andrechek; Seiichi Mori; Rachel E Rempel; Jeffrey T Chang; Joseph R Nevins
Patterns of cell signaling pathway activation that characterize mammary development.
Development (Cambridge, England) 2008;135(14):2403-13.
2008: Carey Anders; David S Hsu; Gloria Broadwater; Chaitanya R Acharya; John A Foekens; Yi Zhang; Yixin Wang; Paul Kelly Marcom; Jeffrey R Marks; Phillip G Febbo; Joseph R Nevins; Anil Potti; Kimberly L Blackwell
Young age at diagnosis correlates with worse prognosis and defines a subset of breast cancers with shared patterns of gene expression.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(20):3324-30.
2008: J Y Leung; Ginger L. Ehmann; Paloma H Giangrande; Joseph R Nevins
A role for Myc in facilitating transcription activation by E2F1.
Oncogene 2008;27(30):4172-9.
2008: Chaitanya R Acharya; David S Hsu; Carey Anders; Ariel Anguiano; Kelly H Salter; Kelli S Walters; Richard C Redman; Sascha A Tuchman; Cynthia A Moylan; Sayan Mukherjee; William T Barry; Holly K Dressman; Geoffrey S Ginsburg; Paul Kelly Marcom; Katherine S Garman; Gary H Lyman; Joseph R Nevins; Anil Potti
Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer.
JAMA : the journal of the American Medical Association 2008;299(13):1574-87.
2008: Guang Yao; Tae Jun Lee; Seiichi Mori; Joseph R Nevins; Lingchong You
A bistable Rb-E2F switch underlies the restriction point.
Nature cell biology 2008;10(4):476-82.
2008: Anil Potti; Joseph R Nevins
Utilization of genomic signatures to direct use of primary chemotherapy.
Current opinion in genetics & development 2008;18(1):62-7.
2008: Sarah K Meadows; Holly K Dressman; Garrett G Muramoto; Heather Himburg; Alice Salter; ZhengZheng Wei; Geoffrey S Ginsburg; Geoff Ginsburg; Nelson J Chao; Joseph R Nevins; John P Chute
Gene expression signatures of radiation response are specific, durable and accurate in mice and humans.
PloS one 2008;3(4):e1912.
2008: Kelly H Salter; Chaitanya R Acharya; Kelli S Walters; Richard Redman; Ariel Anguiano; Katherine S Garman; Carey Anders; Sayan Mukherjee; Holly K Dressman; William T Barry; Paul Kelly Marcom; John Olson; Joseph R Nevins; Anil Potti
An integrated approach to the prediction of chemotherapeutic response in patients with breast cancer.
PloS one 2008;3(4):e1908.
2008: Min Xu; Ming-Chih J Kao; Juan Nunez-Iglesias; Joseph R Nevins; Mike West; Xianghong Jasmine Zhou
An integrative approach to characterize disease-specific pathways and their coordination: a case study in cancer.
BMC genomics 2008;9 Suppl 1():S12.
2008: Carey Anders; Chaitanya R Acharya; David S Hsu; Gloria Broadwater; Katherine S Garman; John A Foekens; Yi Zhang; Yixin Wang; Paul Kelly Marcom; Jeffrey R Marks; Sayan Mukherjee; Joseph R Nevins; Kimberly L Blackwell; Anil Potti
Age-specific differences in oncogenic pathway deregulation seen in human breast tumors.
PloS one 2008;3(1):e1373.
2008: Timothy C Hallstrom; Seiichi Mori; Joseph R Nevins
An E2F1-dependent gene expression program that determines the balance between proliferation and cell death.
Cancer cell 2008;13(1):11-22.
2007: Joseph R Nevins
New breast cancer genes-discovery at the intersection of complex data sets.
Cancer cell 2007;12(6):497-9.
2007: Hervé Bonnefoi; Anil Potti; Mauro Delorenzi; Louis Mauriac; Mario Campone; Michèle Tubiana-Hulin; Thierry Petit; Philippe Rouanet; Jacek Jassem; Emmanuel Blot; Véronique Becette; Pierre Farmer; Sylvie André; Chaitanya R Acharya; Sayan Mukherjee; David Cameron; Jonas Bergh; Joseph R Nevins; Richard D Iggo
Validation of gene signatures that predict the response of breast cancer to neoadjuvant chemotherapy: a substudy of the EORTC 10994/BIG 00-01 clinical trial.
The lancet oncology 2007;8(12):1071-8.
2007: Katherine S Garman; Joseph R Nevins; Anil Potti
Genomic strategies for personalized cancer therapy.
Human molecular genetics 2007;16 Spec No. 2():R226-32.
2007: David S Hsu; Bala S Balakumaran; Chaitanya R Acharya; Vanja Vlahovic; Kelli S Walters; Katherine S Garman; Carey Anders; Richard F Riedel; Johnathan Lancaster; David H Harpole; Holly K Dressman; Joseph R Nevins; Phillip G Febbo; Anil Potti
Pharmacogenomic strategies provide a rational approach to the treatment of cisplatin-resistant patients with advanced cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(28):4350-7.
2007: Paloma H Giangrande; JianXin Zhang; Alice Tanner; Andrea D Eckhart; Rachel E Rempel; Eran R Andrechek; Juliana M Layzer; Janelle R Keys; Per-Otto Hagen; Joseph R Nevins; Walter J Koch; Bruce A Sullenger
Distinct roles of E2F proteins in vascular smooth muscle cell proliferation and intimal hyperplasia.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(32):12988-93.
2007: Joseph R Nevins; Anil Potti
Mining gene expression profiles: expression signatures as cancer phenotypes.
Nature reviews. Genetics 2007;8(8):601-9.
2007: Holly K Dressman; Garrett G Muramoto; Nelson J Chao; Sarah Meadows; Dawn Marshall; Geoffrey S Ginsburg; Joseph R Nevins; John P Chute
Gene expression signatures that predict radiation exposure in mice and humans.
PLoS medicine 2007;4(4):e106.
2007: Holly K Dressman; Andrew Berchuck; Gina Chan; Jun Zhai; Andrea Bild; Robyn A Sayer; Janiel M Cragun; Jennifer Clarke; Regina S Whitaker; Lihua Li; Jonathan Gray; Jeffrey Marks; Geoffrey S Ginsburg; Anil Potti; Mike West; Joseph R Nevins; Johnathan M Lancaster
An integrated genomic-based approach to individualized treatment of patients with advanced-stage ovarian cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(5):517-25.
2007: L-J Kong; Jeffrey T Chang; Andrea Bild; Joseph R Nevins
Compensation and specificity of function within the E2F family.
Oncogene 2007;26(3):321-7.
2007: Weichun Huang; Joseph R Nevins; Uwe Ohler
Phylogenetic simulation of promoter evolution: estimation and modeling of binding site turnover events and assessment of their impact on alignment tools.
Genome biology 2007;8(10):R225.
2006: Jeffrey T Chang; Joseph R Nevins
GATHER: a systems approach to interpreting genomic signatures.
Bioinformatics (Oxford, England) 2006;22(23):2926-33.
2006: Anil Potti; Holly K Dressman; Andrea Bild; Richard F Riedel; Gina Chan; Robyn A Sayer; Janiel M Cragun; Hope Cottrill; Michael J Kelley; Rebecca Petersen; David H Harpole; Jeffrey Marks; Andrew Berchuck; Geoffrey S Ginsburg; Phillip G Febbo; Johnathan Lancaster; Joseph R Nevins
Genomic signatures to guide the use of chemotherapeutics.
Nature medicine 2006;12(11):1294-300.
2006: Skye H Cheng; Cheng-Fang Horng; Mike West; Erich Huang; Jennifer Clarke; Mei-Hua Tsou; Holly K Dressman; Chii-Ming Chen; Stella Y Tsai; James Jer-Min Jian; Mei-Chin Liu; Joseph R Nevins; Andrew T Huang
Genomic prediction of locoregional recurrence after mastectomy in breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(28):4594-602.
2006: Andrea Bild; Anil Potti; Joseph R Nevins
Linking oncogenic pathways with therapeutic opportunities.
Nature reviews. Cancer 2006;6(9):735-41.
2006: Anil Potti; Sayan Mukherjee; Rebecca Petersen; Holly K Dressman; Andrea Bild; Jason Koontz; Robert A Kratzke; Mark A Watson; Michael Kelley; Geoffrey S Ginsburg; Mike West; David H Harpole; Joseph R Nevins
A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer.
The New England journal of medicine 2006;355(6):570-80.
2006: Mike West; Geoffrey S Ginsburg; Andrew T Huang; Joseph R Nevins
Embracing the complexity of genomic data for personalized medicine.
Genome research 2006;16(5):559-66.
2006: Ling-Jie Kong; Alison R Meloni; Joseph R Nevins
The Rb-related p130 protein controls telomere lengthening through an interaction with a Rad50-interacting protein, RINT-1.
Molecular cell 2006;22(1):63-71.
2006: Timothy C Hallstrom; Joseph R Nevins
Jab1 is a specificity factor for E2F1-induced apoptosis.
Genes & development 2006;20(5):613-23.
2006: Anil Potti; Andrea Bild; Holly K Dressman; Deborah A Lewis; Joseph R Nevins; Thomas L Ortel
Gene-expression patterns predict phenotypes of immune-mediated thrombosis.
Blood 2006;107(4):1391-6.
2006: Holly K Dressman; Christopher Hans; Andrea Bild; John Olson; Eric Rosen; Paul Kelly Marcom; Vlayka B Liotcheva; Ellen Jones; Zeljko Vujaskovic; Jeffrey Marks; Mark Dewhirst; Mike West; Joseph R Nevins; Kimberly Blackwell
Gene expression profiles of multiple breast cancer phenotypes and response to neoadjuvant chemotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(3 Pt 1):819-26.
2006: Andrea Bild; Guang Yao; Jeffrey T Chang; Quanli Wang; Anil Potti; Dawn Chasse; Mary-Beth Moore Joshi; David H Harpole; Johnathan M Lancaster; Andrew Berchuck; John Olson; Jeffrey R Marks; Holly K Dressman; Mike West; Joseph R Nevins
Oncogenic pathway signatures in human cancers as a guide to targeted therapies.
Nature 2006;439(7074):353-7.
2005: Ravi Karra; Sreekanth Vemullapalli; Chunming Dong; edward herderick; Xiaohua Song; Kathy Slosek; Joseph R Nevins; Mike West; Pascal J Goldschmidt-Clermont; David Seo
Molecular evidence for arterial repair in atherosclerosis.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(46):16789-94.
2005: Esther P Black; Timothy C Hallstrom; Holly K Dressman; Mike West; Joseph R Nevins
Distinctions in the specificity of E2F function revealed by gene expression signatures.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(44):15948-53.
2005: Alison R Meloni; Chun-Hsiang Lai; Tso-Pang Yao; Joseph R Nevins
A mechanism of COOH-terminal binding protein-mediated repression.
Molecular cancer research : MCR 2005;3(10):575-83.
2005: Mark Delong; Guang Yao; Quanli Wang; Adrian Dobra; Esther P Black; Jeffrey T Chang; Andrea Bild; Mike West; Joseph R Nevins; Holly K Dressman
DIG--a system for gene annotation and functional discovery.
Bioinformatics (Oxford, England) 2005;21(13):2957-9.
2005: Jeremy Rich; Christopher Hans; Beatrix Jones; Edwin S Iversen; Roger E McLendon; B K Ahmed Rasheed; Adrian Dobra; Holly K Dressman; Darell D Bigner; Joseph R Nevins; Mike West
Gene expression profiling and genetic markers in glioblastoma survival.
Cancer research 2005;65(10):4051-8.
2005: Andrew Berchuck; Edwin S Iversen; Johnathan M Lancaster; Jennifer Clarke; Jingqin Luo; Paula Lee; Susan Murphy; Holly K Dressman; Phillip G Febbo; Mike West; Joseph R Nevins; Jeffrey R Marks
Patterns of gene expression that characterize long-term survival in advanced stage serous ovarian cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(10):3686-96.
2005: Wencheng Zhu; Paloma H Giangrande; Joseph R Nevins
Temporal control of cell cycle gene expression mediated by E2F transcription factors.
Cell cycle (Georgetown, Tex.) 2005;4(5):633-6.
2004: Paloma H Giangrande; Wencheng Zhu; Suzanne Schlisio; Xin Sun; Seiichi Mori; Stefan Gaubatz; Joseph R Nevins
A role for E2F6 in distinguishing G1/S- and G2/M-specific transcription.
Genes & development 2004;18(23):2941-51.
2004: Wencheng Zhu; Paloma H Giangrande; Joseph R Nevins
E2Fs link the control of G1/S and G2/M transcription.
The EMBO journal 2004;23(23):4615-26.
2004: Jennifer Clarke; Erich Huang; Joseph R Nevins; Quanli Wang; Mike West
Bayesian analysis of binary prediction tree models for retrospectively sampled outcomes.
Biostatistics (Oxford, England) 2004;5(4):587-601.
2004: David Seo; Tao Wang; Holly K Dressman; edward herderick; Edwin S Iversen; Chunming Dong; Korkut Vata; Carmelo A Milano; Fabio Rigat; Jennifer Clarke; Joseph R Nevins; Mike West; Pascal J Goldschmidt-Clermont
Gene expression phenotypes of atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(10):1922-7.
2004: Erich Huang; Joseph R Nevins; Mike West; Paul C Kuo
An overview of genomic data analysis.
Surgery 2004;136(3):497-9.
2004: Jennifer Clarke; Erich Huang; Holly K Dressman; Cheng-Fang Horng; Skye H Cheng; Mei-Hua Tsou; Chii-Ming Chen; Andrea Bild; Edwin S Iversen; Andrew T Huang; Joseph R Nevins; Mike West
Integrated modeling of clinical and gene expression information for personalized prediction of disease outcomes.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(22):8431-6.
2004: Andrew Berchuck; Edwin S Iversen; Johnathan M Lancaster; Holly K Dressman; Mike West; Joseph R Nevins; Jeffrey R Marks
Prediction of optimal versus suboptimal cytoreduction of advanced-stage serous ovarian cancer with the use of microarrays.
American journal of obstetrics and gynecology 2004;190(4):910-25.
2004: Elizabeth Yeh; Melissa Cunningham; Hugh Arnold; Dawn Chasse; Teresa Monteith; Giovanni Ivaldi; William C Hahn; P Todd Stukenberg; Shirish Shenolikar; Takafumi Uchida; Christopher M Counter; Joseph R Nevins; Anthony R Means; Rosalie C Pelz
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells.
Nature cell biology 2004;6(4):308-18.
2004: Paloma H Giangrande; Wencheng Zhu; Rachel E Rempel; Nina Laakso; Joseph R Nevins
Combinatorial gene control involving E2F and E Box family members.
The EMBO journal 2004;23(6):1336-47.
2004: Jeanette Gowen Cook; Dawn Chasse; Joseph R Nevins
The regulated association of Cdt1 with minichromosome maintenance proteins and Cdc6 in mammalian cells.
The Journal of biological chemistry 2004;279(10):9625-33.
2004: Johnathan M Lancaster; Holly K Dressman; Regina S Whitaker; Laura Havrilesky; Jonathan Gray; Jeffrey R Marks; Joseph R Nevins; Andrew Berchuck
Gene expression patterns that characterize advanced stage serous ovarian cancers.
Journal of the Society for Gynecologic Investigation 2004;11(1):51-9.
2003: Joseph R Nevins; Erich Huang; Holly K Dressman; Jennifer Clarke; Andrew T Huang; Mike West
Towards integrated clinico-genomic models for personalized medicine: combining gene expression signatures and clinical factors in breast cancer outcomes prediction.
Human molecular genetics 2003;12 Spec No 2():R153-7.
2003: Timothy C Hallstrom; Joseph R Nevins
Specificity in the activation and control of transcription factor E2F-dependent apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(19):10848-53.
2003: Erich Huang; Esther P Black; Holly K Dressman; Mike West; Joseph R Nevins
Gene expression phenotypes of oncogenic signaling pathways.
Cell cycle (Georgetown, Tex.) 2003;2(5):415-7.
2003: Esther P Black; Erich Huang; Holly K Dressman; Rachel E Rempel; Nina Laakso; Sylvia Asa; Seiichi Ishida; Mike West; Joseph R Nevins
Distinct gene expression phenotypes of cells lacking Rb and Rb family members.
Cancer research 2003;63(13):3716-23.
2003: Erich Huang; Seiichi Ishida; Jennifer Clarke; Holly K Dressman; Andrea Bild; Mark T Kloos; Mark D'Amico; Richard G Pestell; Mike West; Joseph R Nevins
Gene expression phenotypic models that predict the activity of oncogenic pathways.
Nature genetics 2003;34(2):226-30.
2003: Paloma H Giangrande; Timothy C Hallstrom; Chainarong Tunyaplin; Kathryn Calame; Joseph R Nevins
Identification of E-box factor TFE3 as a functional partner for the E2F3 transcription factor.
Molecular and cellular biology 2003;23(11):3707-20.
2003: Erich Huang; Skye H Cheng; Holly K Dressman; Jennifer Clarke; Mei-Hua Tsou; Cheng-Fang Horng; Andrea Bild; Edwin S Iversen; Ming Liao; Chii Ming Chen; Mike West; Joseph R Nevins; Andrew T Huang
Gene expression predictors of breast cancer outcomes.
Lancet 2003;361(9369):1590-6.
2003: Erich Huang; Mike West; Joseph R Nevins
Gene expression profiling for prediction of clinical characteristics of breast cancer.
Recent progress in hormone research 2003;58():55-73.
2002: Suzanne Schlisio; Terri Halperin; Miguel Vidal; Joseph R Nevins
Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F function.
The EMBO journal 2002;21(21):5775-86.
2002: Rosalie C Pelz; Joseph R Nevins
Signaling networks that link cell proliferation and cell fate.
The Journal of biological chemistry 2002;277(14):11617-20.
2002: Jeanette Gowen Cook; Chi-Hyun Park; Thomas W Burke; Gustavo Leone; James DeGregori; Amber Engel; Joseph R Nevins
Analysis of Cdc6 function in the assembly of mammalian prereplication complexes.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(3):1347-52.
2002: Rainer Spang; Harry Zuzan; Mike West; Joseph R Nevins; Carrie Blanchette; Jeffrey R Marks
Prediction and uncertainty in the analysis of gene expression profiles.
In silico biology 2002;2(3):369-81.
2001: Lizhao Wu; Cynthia Timmers; Baidehi Maiti; Harold I Saavedra; L Sang; G T Chong; F Nuckolls; Paloma H Giangrande; Fred A Wright; Seth J Field; Michael E Greenberg; Stuart H Orkin; Joseph R Nevins; Michael L Robinson; Gustavo Leone
The E2F1-3 transcription factors are essential for cellular proliferation.
Nature 2001;414(6862):457-62.
2001: Mike West; Carrie Blanchette; Holly K Dressman; Erich Huang; Seiichi Ishida; Rainer Spang; Harry Zuzan; John Olson; Jeffrey R Marks; Joseph R Nevins
Predicting the clinical status of human breast cancer by using gene expression profiles.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(20):11462-7.
2001: W C Lin; F T Lin; Joseph R Nevins
Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation.
Genes & development 2001;15(14):1833-44.
2001: Gustavo Leone; Rosalie C Pelz; Erich Huang; Rachel E Rempel; F Nuckolls; C H Park; Paloma H Giangrande; Lizhao Wu; Harold I Saavedra; Seth J Field; M A Thompson; H Yang; Y Fujiwara; Michael E Greenberg; Stuart H Orkin; Clay Smith; Joseph R Nevins
Myc requires distinct E2F activities to induce S phase and apoptosis.
Molecular cell 2001;8(1):105-13.
2001: Seiichi Ishida; Erich Huang; Harry Zuzan; Rainer Spang; Gustavo Leone; Mike West; Joseph R Nevins
Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis.
Molecular and cellular biology 2001;21(14):4684-99.
2001: T W Burke; Jeanette Gowen Cook; Maki Asano; Joseph R Nevins
Replication factors MCM2 and ORC1 interact with the histone acetyltransferase HBO1.
The Journal of biological chemistry 2001;276(18):15397-408.
2001: Joseph R Nevins
The Rb/E2F pathway and cancer.
Human molecular genetics 2001;10(7):699-703.
2001: James Brugarolas; B F Haynes; Joseph R Nevins
Towards a genomic-based diagnosis.
Lancet 2001;357(9252):249-50.
2000: D S Smith; Gustavo Leone; James DeGregori; Mohamed Ahmed; Mazin B Qumsiyeh; Joseph R Nevins
Induction of DNA replication in adult rat neurons by deregulation of the retinoblastoma/E2F G1 cell cycle pathway.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2000;11(12):625-33.
2000: Rosalie C Pelz; F Nuckolls; Eric Haura; Y Taya; Katsuyuki Tamai; Joseph R Nevins
Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.
Genes & development 2000;14(19):2501-14.
2000: Stefan Gaubatz; GJ Lindeman; Seiichi Ishida; L Jakoi; Joseph R Nevins; David M Livingston; Rachel E Rempel
E2F4 and E2F5 play an essential role in pocket protein-mediated G1 control.
Molecular cell 2000;6(3):729-35.
2000: Rachel E Rempel; M T Saenz-Robles; Robert W Storms; Scott G Morham; Seiichi Ishida; A Engel; L Jakoi; M F Melhem; J M Pipas; Clay Smith; Joseph R Nevins
Loss of E2F4 activity leads to abnormal development of multiple cellular lineages.
Molecular cell 2000;6(2):293-306.
2000: M R Adams; Rosalie C Pelz; F Nuckolls; Gustavo Leone; Joseph R Nevins
Complex transcriptional regulatory mechanisms control expression of the E2F3 locus.
Molecular and cellular biology 2000;20(10):3633-9.
2000: Gustavo Leone; F Nuckolls; Seiichi Ishida; M Adams; Rosalie C Pelz; L Jakoi; alexander miron; Joseph R Nevins
Identification of a novel E2F3 product suggests a mechanism for determining specificity of repression by Rb proteins.
Molecular and cellular biology 2000;20(10):3626-32.
1999: Alison R Meloni; E J Smith; Joseph R Nevins
A mechanism for Rb/p130-mediated transcription repression involving recruitment of the CtBP corepressor.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(17):9574-9.
1999: Gustavo Leone; James DeGregori; L Jakoi; Jeanette Gowen Cook; Joseph R Nevins
Collaborative role of E2F transcriptional activity and G1 cyclindependent kinase activity in the induction of S phase.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(12):6626-31.
1999: Rosalie C Pelz; Gustavo Leone; James DeGregori; Joseph R Nevins
Ras enhances Myc protein stability.
Molecular cell 1999;3(2):169-79.
1998: Joseph R Nevins
Toward an understanding of the functional complexity of the E2F and retinoblastoma families.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998;9(8):585-93.
1998: Gustavo Leone; James DeGregori; Z Yan; L Jakoi; Seiichi Ishida; R Sanders Williams; Joseph R Nevins
E2F3 activity is regulated during the cell cycle and is required for the induction of S phase.
Genes & development 1998;12(14):2120-30.
1998: E J Smith; Gustavo Leone; Joseph R Nevins
Distinct mechanisms control the accumulation of the Rb-related p107 and p130 proteins during cell growth.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998;9(4):297-303.
1998: Timothy F Kowalik; James DeGregori; Gustavo Leone; L Jakoi; Joseph R Nevins
E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998;9(2):113-8.
1997: Joseph R Nevins; Gustavo Leone; James DeGregori; L Jakoi
Role of the Rb/E2F pathway in cell growth control.
Journal of cellular physiology 1997;173(2):233-6.
1997: Rosalie C Pelz; K Ohtani; Joseph R Nevins
Identification of positively and negatively acting elements regulating expression of the E2F2 gene in response to cell growth signals.
Molecular and cellular biology 1997;17(9):5227-35.
1997: James DeGregori; Gustavo Leone; alexander miron; L Jakoi; Joseph R Nevins
Distinct roles for E2F proteins in cell growth control and apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(14):7245-50.
1997: Gustavo Leone; James DeGregori; Rosalie C Pelz; L Jakoi; Joseph R Nevins
Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F.
Nature 1997;387(6631):422-6.
1997: Joseph R Nevins; James DeGregori; L Jakoi; Gustavo Leone
Functional analysis of E2F transcription factor.
Methods in enzymology 1997;283():205-19.
1996: J Ishizaki; Joseph R Nevins; Bruce A Sullenger
Inhibition of cell proliferation by an RNA ligand that selectively blocks E2F function.
Nature medicine 1996;2(12):1386-9.
1996: K Ohtani; James DeGregori; Gustavo Leone; D R Herendeen; Thomas J Kelly; Joseph R Nevins
Expression of the HsOrc1 gene, a human ORC1 homolog, is regulated by cell proliferation via the E2F transcription factor.
Molecular and cellular biology 1996;16(12):6977-84.
1996: E J Smith; Gustavo Leone; James DeGregori; L Jakoi; Joseph R Nevins
The accumulation of an E2F-p130 transcriptional repressor distinguishes a G0 cell state from a G1 cell state.
Molecular and cellular biology 1996;16(12):6965-76.
1996: M Asano; Joseph R Nevins; Robin P Wharton
Ectopic E2F expression induces S phase and apoptosis in Drosophila imaginal discs.
Genes & development 1996;10(11):1422-32.
1996: W.Douglas Cress; Joseph R Nevins
A role for a bent DNA structure in E2F-mediated transcription activation.
Molecular and cellular biology 1996;16(5):2119-27.
1996: M A Ikeda; L Jakoi; Joseph R Nevins
A unique role for the Rb protein in controlling E2F accumulation during cell growth and differentiation.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(8):3215-20.
1996: W.Douglas Cress; Joseph R Nevins
Use of the E2F transcription factor by DNA tumor virus regulatory proteins.
Current topics in microbiology and immunology 1996;208():63-78.
1995: K Ohtani; James DeGregori; Joseph R Nevins
Regulation of the cyclin E gene by transcription factor E2F1.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(26):12146-50.
1995: James DeGregori; Gustavo Leone; K Ohtani; alexander miron; Joseph R Nevins
E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity.
Genes & development 1995;9(23):2873-87.
1995: James DeGregori; Timothy F Kowalik; Joseph R Nevins
Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes.
Molecular and cellular biology 1995;15(8):4215-24.
1995: D H Yan; E A Weiss; Joseph R Nevins
Identification of an activity in B-cell extracts that selectively impairs the formation of an immunoglobulin mu s poly(A) site processing complex.
Molecular and cellular biology 1995;15(4):1901-6.
1995: Timothy F Kowalik; James DeGregori; J K Schwarz; Joseph R Nevins
E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis.
Journal of virology 1995;69(4):2491-500.
1995: J K Schwarz; C H Bassing; Imre Kovesdi; Michael B Datto; Michael A Blazing; S George; Xiao-Fan Wang; Joseph R Nevins
Expression of the E2F1 transcription factor overcomes type beta transforming growth factor-mediated growth suppression.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(2):483-7.
1995: E J Smith; Joseph R Nevins
The Rb-related p107 protein can suppress E2F function independently of binding to cyclin A/cdk2.
Molecular and cellular biology 1995;15(1):338-44.
1995: Joseph R Nevins
Adenovirus E1A: transcription regulation and alteration of cell growth control.
Current topics in microbiology and immunology 1995;199 ( Pt 3)():25-32.
1994: D G Johnson; W.Douglas Cress; L Jakoi; Joseph R Nevins
Oncogenic capacity of the E2F1 gene.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(26):12823-7.
1994: Virginia B Kraus; J A Inostroza; K Yeung; Danny Reinberg; Joseph R Nevins
Interaction of the Dr1 inhibitory factor with the TATA binding protein is disrupted by adenovirus E1A.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(14):6279-82.
1994: W.Douglas Cress; Joseph R Nevins
Interacting domains of E2F1, DP1, and the adenovirus E4 protein.
Journal of virology 1994;68(7):4213-9.
1994: D G Johnson; K Ohtani; Joseph R Nevins
Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression.
Genes & development 1994;8(13):1514-25.
1994: K Ohtani; Joseph R Nevins
Functional properties of a Drosophila homolog of the E2F1 gene.
Molecular and cellular biology 1994;14(3):1603-12.
1994: Joseph R Nevins
Cell cycle targets of the DNA tumor viruses.
Current opinion in genetics & development 1994;4(1):130-4.
1993: M A Ikeda; Joseph R Nevins
Identification of distinct roles for separate E1A domains in disruption of E2F complexes.
Molecular and cellular biology 1993;13(11):7029-35.
1993: Joseph R Nevins
Disruption of cell-cycle control by viral oncoproteins.
Biochemical Society transactions 1993;21(4):935-8.
1993: W.Douglas Cress; D G Johnson; Joseph R Nevins
A genetic analysis of the E2F1 gene distinguishes regulation by Rb, p107, and adenovirus E4.
Molecular and cellular biology 1993;13(10):6314-25.
1993: D G Johnson; J K Schwarz; W.Douglas Cress; Joseph R Nevins
Expression of transcription factor E2F1 induces quiescent cells to enter S phase.
Nature 1993;365(6444):349-52.
1993: Karen P Mann; E A Weiss; Joseph R Nevins
Alternative poly(A) site utilization during adenovirus infection coincides with a decrease in the activity of a poly(A) site processing factor.
Molecular and cellular biology 1993;13(4):2411-9.
1993: J K Schwarz; Stephen Devoto; E J Smith; Srikumar Chellappan; L Jakoi; Joseph R Nevins
Interactions of the p107 and Rb proteins with E2F during the cell proliferation response.
The EMBO journal 1993;12(3):1013-20.
1992: Joseph R Nevins
E2F: a link between the Rb tumor suppressor protein and viral oncoproteins.
Science (New York, N.Y.) 1992;258(5081):424-9.
1992: Virginia B Kraus; E Moran; Joseph R Nevins
Promoter-specific trans-activation by the adenovirus E1A12S product involves separate E1A domains.
Molecular and cellular biology 1992;12(10):4391-9.
1992: Srikumar Chellappan; Virginia B Kraus; B Kroger; K Munger; Peter M Howley; William Phelps; Joseph R Nevins
Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(10):4549-53.
1992: S W Hiebert; Srikumar Chellappan; Jonathan M Horowitz; Joseph R Nevins
The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F.
Genes & development 1992;6(2):177-85.
1992: Stephen Devoto; maria mudryj; J Pines; Tony Hunter; Joseph R Nevins
A cyclin A-protein kinase complex possesses sequence-specific DNA binding activity: p33cdk2 is a component of the E2F-cyclin A complex.
Cell 1992;68(1):167-76.
1991: William Phelps; Srilata Bagchi; J A Barnes; Pradip Raychaudhuri; Virginia B Kraus; K Münger; Peter M Howley; Joseph R Nevins
Analysis of trans activation by human papillomavirus type 16 E7 and adenovirus 12S E1A suggests a common mechanism.
Journal of virology 1991;65(12):6922-30.
1991: Joseph R Nevins
Transcriptional activation by viral regulatory proteins.
Trends in biochemical sciences 1991;16(11):435-9.
1991: S D Neill; Joseph R Nevins
Genetic analysis of the adenovirus E4 6/7 trans activator: interaction with E2F and induction of a stable DNA-protein complex are critical for activity.
Journal of virology 1991;65(10):5364-73.
1991: Pradip Raychaudhuri; Srilata Bagchi; Stephen Devoto; Virginia B Kraus; E Moran; Joseph R Nevins
Domains of the adenovirus E1A protein required for oncogenic activity are also required for dissociation of E2F transcription factor complexes.
Genes & development 1991;5(7):1200-11.
1991: S W Hiebert; M Blake; J Azizkhan; Joseph R Nevins
Role of E2F transcription factor in E1A-mediated trans activation of cellular genes.
Journal of virology 1991;65(7):3547-52.
1991: maria mudryj; Stephen Devoto; S W Hiebert; Tony Hunter; J Pines; Joseph R Nevins
Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A.
Cell 1991;65(7):1243-53.
1991: Srikumar Chellappan; S Hiebert; maria mudryj; Jonathan M Horowitz; Joseph R Nevins
The E2F transcription factor is a cellular target for the RB protein.
Cell 1991;65(6):1053-61.
1991: Joseph R Nevins
Utilization of cellular transcription factors for adenovirus-induced transcription.
Virus research 1991;20(1):1-10.
1991: John Nicholas; Joseph R Nevins
Distinct DNA targets for trans-activation by HTLV-1 tax and adenovirus E1A.
Virology 1991;182(1):156-67.
1991: Yasmath Ahmed; G M Gilmartin; S M Hanly; Joseph R Nevins; Warner Greene
The HTLV-I Rex response element mediates a novel form of mRNA polyadenylation.
Cell 1991;64(4):727-37.
1991: Joseph R Nevins; Srikumar Chellappan; maria mudryj; S Hiebert; S Devoto; J Horowitz; Tony Hunter; J Pines
E2F transcription factor is a target for the RB protein and the cyclin A protein.
Cold Spring Harbor symposia on quantitative biology 1991;56():157-62.
1991: E A Weiss; G M Gilmartin; Joseph R Nevins
Poly(A) site efficiency reflects the stability of complex formation involving the downstream element.
The EMBO journal 1991;10(1):215-9.
1990: R J Weigel; Stephen Devoto; Joseph R Nevins
Adenovirus 12S E1A gene represses differentiation of F9 teratocarcinoma cells.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(24):9878-82.
1990: R J Weigel; Joseph R Nevins
Adenovirus infection of differentiated F9 cells results in a global shut-off of differentiation-induced gene expression.
Nucleic acids research 1990;18(20):6107-12.
1990: Robert J. Rooney; Pradip Raychaudhuri; Joseph R Nevins
E4F and ATF, two transcription factors that recognize the same site, can be distinguished both physically and functionally: a role for E4F in E1A trans activation.
Molecular and cellular biology 1990;10(10):5138-49.
1990: Srilata Bagchi; Pradip Raychaudhuri; Joseph R Nevins
Adenovirus E1A proteins can dissociate heteromeric complexes involving the E2F transcription factor: a novel mechanism for E1A trans-activation.
Cell 1990;62(4):659-69.
1990: Srikumar Chellappan; Joseph R Nevins
DNA octamer element can confer E1A trans-activation, and adenovirus infection results in a stimulation of the DNA-binding activity of OTF-1/NFIII factor.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(15):5878-82.
1990: maria mudryj; S W Hiebert; Joseph R Nevins
A role for the adenovirus inducible E2F transcription factor in a proliferation dependent signal transduction pathway.
The EMBO journal 1990;9(7):2179-84.
1990: Pradip Raychaudhuri; Srilata Bagchi; S D Neill; Joseph R Nevins
Activation of the E2F transcription factor in adenovirus-infected cells involves E1A-dependent stimulation of DNA-binding activity and induction of cooperative binding mediated by an E4 gene product.
Journal of virology 1990;64(6):2702-10.
1990: S D Neill; C Hemstrom; A Virtanen; Joseph R Nevins
An adenovirus E4 gene product trans-activates E2 transcription and stimulates stable E2F binding through a direct association with E2F.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(5):2008-12.
1990: M C Simon; Robert J. Rooney; T M Fisch; Nathaniel Heintz; Joseph R Nevins
E1A-dependent trans-activation of the c-fos promoter requires the TATAA sequence.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(2):513-7.
1989: G M Gilmartin; Joseph R Nevins
An ordered pathway of assembly of components required for polyadenylation site recognition and processing.
Genes & development 1989;3(12B):2180-90.
1989: R Reichel; S D Neill; Imre Kovesdi; M C Simon; Pradip Raychaudhuri; Joseph R Nevins
The adenovirus E4 gene, in addition to the E1A gene, is important for trans-activation of E2 transcription and for E2F activation.
Journal of virology 1989;63(9):3643-50.
1989: K S Young; R Weigel; S Hiebert; Joseph R Nevins
Adenovirus E1A-mediated negative control of genes activated during F9 differentiation.
Molecular and cellular biology 1989;9(7):3109-13.
1989: Srilata Bagchi; Pradip Raychaudhuri; Joseph R Nevins
Phosphorylation-dependent activation of the adenovirus-inducible E2F transcription factor in a cell-free system.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(12):4352-6.
1989: Pradip Raychaudhuri; Srilata Bagchi; Joseph R Nevins
DNA-binding activity of the adenovirus-induced E4F transcription factor is regulated by phosphorylation.
Genes & development 1989;3(5):620-7.
1989: S W Hiebert; Martin Lipp; Joseph R Nevins
E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(10):3594-8.
1989: Amy Yee; Pradip Raychaudhuri; L Jakoi; Joseph R Nevins
The adenovirus-inducible factor E2F stimulates transcription after specific DNA binding.
Molecular and cellular biology 1989;9(2):578-85.
1988: I Lazaridis; A Babich; Joseph R Nevins
Role of the adenovirus 72-kDa DNA binding protein in the rapid decay of early viral mRNA.
Virology 1988;165(2):438-45.
1988: Guy R Adami; Joseph R Nevins
Splice site selection dominates over poly(A) site choice in RNA production from complex adenovirus transcription units.
The EMBO journal 1988;7(7):2107-16.
1988: Joseph R Nevins; Pradip Raychaudhuri; Amy Yee; Robert J. Rooney; Imre Kovesdi; R Reichel
Transactivation by the adenovirus E1A gene.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1988;66(6):578-83.
1988: A MICHAEL MCDEVITT; G M Gilmartin; W H Reeves; Joseph R Nevins
Multiple factors are required for poly(A) addition to a mRNA 3' end.
Genes & development 1988;2(5):588-97.
1988: G M Gilmartin; A MICHAEL MCDEVITT; Joseph R Nevins
Multiple factors are required for specific RNA cleavage at a poly(A) addition site.
Genes & development 1988;2(5):578-87.
1988: G Galli; J Guise; P W Tucker; Joseph R Nevins
Poly(A) site choice rather than splice site choice governs the regulated production of IgM heavy-chain RNAs.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(8):2439-43.
1988: M C Simon; T M Fisch; B J Benecke; Joseph R Nevins; Nathaniel Heintz
Definition of multiple, functionally distinct TATA elements, one of which is a target in the hsp70 promoter for E1A regulation.
Cell 1988;52(5):723-9.
1988: R Reichel; Imre Kovesdi; Joseph R Nevins
Activation of a preexisting cellular factor as a basis for adenovirus E1A-mediated transcription control.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(2):387-90.
1987: Pradip Raychaudhuri; Robert J. Rooney; Joseph R Nevins
Identification of an E1A-inducible cellular factor that interacts with regulatory sequences within the adenovirus E4 promoter.
The EMBO journal 1987;6(13):4073-81.
1987: M C Simon; K Kitchener; Hung-Teh Kao; E Hickey; L Weber; R Voellmy; Nathaniel Heintz; Joseph R Nevins
Selective induction of human heat shock gene transcription by the adenovirus E1A gene products, including the 12S E1A product.
Molecular and cellular biology 1987;7(8):2884-90.
1987: Imre Kovesdi; M Satake; K Furukawa; R Reichel; Y Ito; Joseph R Nevins
A factor discriminating between the wild-type and a mutant polyomavirus enhancer.
Nature 1987;328(6125):87-9.
1987: G Galli; J W Guise; A MICHAEL MCDEVITT; P W Tucker; Joseph R Nevins
Relative position and strengths of poly(A) sites as well as transcription termination are critical to membrane versus secreted mu-chain expression during B-cell development.
Genes & development 1987;1(5):471-81.
1987: Amy Yee; R Reichel; Imre Kovesdi; Joseph R Nevins
Promoter interaction of the E1A-inducible factor E2F and its potential role in the formation of a multi-component complex.
The EMBO journal 1987;6(7):2061-8.
1987: Imre Kovesdi; R Reichel; Joseph R Nevins
Role of an adenovirus E2 promoter binding factor in E1A-mediated coordinate gene control.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(8):2180-4.
1987: R Reichel; Imre Kovesdi; Joseph R Nevins
Developmental control of a promoter-specific factor that is also regulated by the E1A gene product.
Cell 1987;48(3):501-6.
1987: Leszek Kaczmarek; B Calabretta; Hung-Teh Kao; Nathaniel Heintz; Joseph R Nevins; R Baserga
Control of hsp70 RNA levels in human lymphocytes.
The Journal of cell biology 1987;104(2):183-7.
1986: Imre Kovesdi; R Reichel; Joseph R Nevins
Identification of a cellular transcription factor involved in E1A trans-activation.
Cell 1986;45(2):219-28.
1986: Imre Kovesdi; R Reichel; Joseph R Nevins
E1A transcription induction: enhanced binding of a factor to upstream promoter sequences.
Science (New York, N.Y.) 1986;231(4739):719-22.
1985: Hung-Teh Kao; O Capasso; Nathaniel Heintz; Joseph R Nevins
Cell cycle control of the human HSP70 gene: implications for the role of a cellular E1A-like function.
Molecular and cellular biology 1985;5(4):628-33.