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Yvette Newbatt

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Yvette M Newbatt; Jade A Strover; Rosemary Burke; Ian Collins; Faith E Davies; Anthea Hardcastle; P Craig McAndrew; Amin Mirza; Gareth J Morgan; Rob L M van Montfort
Identification of autophosphorylation inhibitors of the inositol-requiring enzyme 1 alpha (IRE1α) by high-throughput screening using a DELFIA assay.
Nicola E Wilsher; Will J Court; Ruth Ruddle; Yvette M Newbatt; Wynne Aherne; Peter W Sheldrake; Neil P Jones; Matilda Katan; Suzanne A Eccles; Florence I Raynaud
The phosphoinositide-specific phospholipase C inhibitor U73122 (1-(6-((17beta-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione) spontaneously forms conjugates with common components of cell culture medium.
Samantha Burns; Jonathan Travers; Ian Collins; Martin G Rowlands; Yvette M Newbatt; Neil Thompson; Michelle D Garrett; Paul Workman; Wynne Aherne
Identification of small-molecule inhibitors of protein kinase B (PKB/AKT) in an AlphaScreenTM high-throughput screen.

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All Publications

2013: Yvette M Newbatt; Jade A Strover; Rosemary Burke; Ian Collins; Faith E Davies; Anthea Hardcastle; P Craig McAndrew; Amin Mirza; Gareth J Morgan; Rob L M van Montfort
Identification of autophosphorylation inhibitors of the inositol-requiring enzyme 1 alpha (IRE1α) by high-throughput screening using a DELFIA assay.
Journal of biomolecular screening 2013;18(3):298-308.
2007: Nicola E Wilsher; Will J Court; Ruth Ruddle; Yvette M Newbatt; Wynne Aherne; Peter W Sheldrake; Neil P Jones; Matilda Katan; Suzanne A Eccles; Florence I Raynaud
The phosphoinositide-specific phospholipase C inhibitor U73122 (1-(6-((17beta-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione) spontaneously forms conjugates with common components of cell culture medium.
Drug metabolism and disposition: the biological fate of chemicals 2007;35(7):1017-22.
2006: Samantha Burns; Jonathan Travers; Ian Collins; Martin G Rowlands; Yvette M Newbatt; Neil Thompson; Michelle D Garrett; Paul Workman; Wynne Aherne
Identification of small-molecule inhibitors of protein kinase B (PKB/AKT) in an AlphaScreenTM high-throughput screen.
Journal of biomolecular screening 2006;11(7):822-7.
2006: Yvette M Newbatt; Samantha Burns; Robert Hayward; Steven Whittaker; Ruth Kirk; Christopher Marshall; Caroline Springer; Edward McDonald; Richard Marais; Paul Workman; Wynne Aherne
Identification of inhibitors of the kinase activity of oncogenic V600E BRAF in an enzyme cascade high-throughput screen.
Journal of biomolecular screening 2006;11(2):145-54.
2005: Lindsay Stimson; Martin G Rowlands; Yvette M Newbatt; Nicola F Smith; Florence I Raynaud; Paul Rogers; Vassilios Bavetsias; Stephen Gorsuch; Michael Jarman; Andrew Bannister; Tony Kouzarides; Edward McDonald; Paul Workman; G Wynne Aherne
Isothiazolones as inhibitors of PCAF and p300 histone acetyltransferase activity.
Molecular cancer therapeutics 2005;4(10):1521-32.
2004: Chongbo Sun; Yvette M Newbatt; Leon Douglas; Paul Workman; Wynne Aherne; Spiros Linardopoulos
High-throughput screening assay for identification of small molecule inhibitors of Aurora2/STK15 kinase.
Journal of biomolecular screening 2004;9(5):391-7.
2004: Martin G Rowlands; Yvette M Newbatt; Chrisostomos Prodromou; Laurence H Pearl; Paul Workman; Wynne Aherne
High-throughput screening assay for inhibitors of heat-shock protein 90 ATPase activity.
Analytical biochemistry 2004;327(2):176-83.
2003: Matilda Katan; Rosie Rodriguez; Miho Matsuda; Yvette M Newbatt; G Wynne Aherne
Structural and mechanistic aspects of phospholipase Cgamma regulation.
Advances in enzyme regulation 2003;43():77-85.
2001: F Turlais; Anthea Hardcastle; Martin G Rowlands; Yvette M Newbatt; A Bannister; Tony Kouzarides; Paul Workman; G Wynne Aherne
High-throughput screening for identification of small molecule inhibitors of histone acetyltransferases using scintillating microplates (FlashPlate).
Analytical biochemistry 2001;298(1):62-8.