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Andrew Newby

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TOP 3
Andrew C Newby
Coronary vein grafting: the flags keep waving but the game goes on.
Wei-Chun Huang; Jason L Johnson; Graciela B Sala-Newby; Angela Susana; Andrew C Newby
Classical macrophage activation up-regulates several matrix metalloproteinases through mitogen activated protein kinases and nuclear factor-κB.
Stephen J White; Elaine M Hayes; Anton J G Horrevoets; Jamie Y Jeremy; Stéphanie Lehoux; Andrew C Newby
Characterization of the differential response of endothelial cells exposed to normal and elevated laminar shear stress.

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All Publications

2013: Andrew C Newby
Coronary vein grafting: the flags keep waving but the game goes on.
Cardiovascular research 2013;97(2):193-4.
2012: Wei-Chun Huang; Jason L Johnson; Graciela B Sala-Newby; Angela Susana; Andrew C Newby
Classical macrophage activation up-regulates several matrix metalloproteinases through mitogen activated protein kinases and nuclear factor-κB.
PloS one 2012;7(8):e42507.
2011: Stephen J White; Elaine M Hayes; Anton J G Horrevoets; Jamie Y Jeremy; Stéphanie Lehoux; Andrew C Newby
Characterization of the differential response of endothelial cells exposed to normal and elevated laminar shear stress.
Journal of cellular physiology 2011;226(11):2841-8.
2011: Jason L Johnson; Amrita Dwivedi; Sarah George; Michelle Somerville; Andrew C Newby
Matrix metalloproteinase (MMP)-3 activates MMP-9 mediated vascular smooth muscle cell migration and neointima formation in mice.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(9):e35-44.
2011: Buket Reel; Graciela B Sala-Newby; Wei-Chun Huang; Andrew C Newby
Diverse patterns of cyclooxygenase-independent metalloproteinase gene regulation in human monocytes.
British journal of pharmacology 2011;163(8):1679-90.
2011: Jason L Johnson; Laurent Devel; Bertrand Czarny; Sarah George; Christopher L Jackson; Vassilis Rogakos; Fabrice Beau; Athanasios Yiotakis; Andrew C Newby; Vincent Dive
A selective matrix metalloproteinase-12 inhibitor retards atherosclerotic plaque development in apolipoprotein E-knockout mice.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(3):528-35.
2011: Richard C Hewer; Graciela B Sala-Newby; Yih-Jer Wu; Andrew C Newby; Mark Bond
PKA and Epac synergistically inhibit smooth muscle cell proliferation.
Journal of molecular and cellular cardiology 2011;50(1):87-98.
2010: Anita C Thomas; Andrew C Newby
Effect of matrix metalloproteinase-9 knockout on vein graft remodelling in mice.
Journal of vascular research 2010;47(4):299-308.
2009: Yih-Jer Wu; Graciela B Sala-Newby; Kuo-Tung Shu; Hung-I Yeh; Keiichi I Nakayama; Keiko Nakayama; Andrew C Newby; Mark Bond
S-phase kinase-associated protein-2 (Skp2) promotes vascular smooth muscle cell proliferation and neointima formation in vivo.
Journal of vascular surgery 2009;50(5):1135-42.
2009: Jason L Johnson; Andrew C Newby
Macrophage heterogeneity in atherosclerotic plaques.
Current opinion in lipidology 2009;20(5):370-8.
2009: Anita C Thomas; Marcella J Wyatt; Andrew C Newby
Reduction of early vein graft thrombosis by tissue plasminogen activator gene transfer.
Thrombosis and haemostasis 2009;102(1):145-52.
2009: Andrew C Newby; Sarah George; Yasmin Ismail; Jason L Johnson; Graciela B Sala-Newby; Anita C Thomas
Vulnerable atherosclerotic plaque metalloproteinases and foam cell phenotypes.
Thrombosis and haemostasis 2009;101(6):1006-11.
2008: Andrew C Newby
Metalloproteinase expression in monocytes and macrophages and its relationship to atherosclerotic plaque instability.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(12):2108-14.
2008: Saima Muzaffar; Nilima Shukla; Mark Bond; Graciela B Sala-Newby; Andrew C Newby; Gianni Angelini; Jamie Y Jeremy
Superoxide from NADPH oxidase upregulates type 5 phosphodiesterase in human vascular smooth muscle cells: inhibition with iloprost and NONOate.
British journal of pharmacology 2008;155(6):847-56.
2008: Mark Bond; Yih-Jer Wu; Graciela B Sala-Newby; Andrew C Newby
Rho GTPase, Rac1, regulates Skp2 levels, vascular smooth muscle cell proliferation, and intima formation in vitro and in vivo.
Cardiovascular research 2008;80(2):290-8.
2008: Jason L Johnson; Graciela B Sala-Newby; Yasmin Ismail; CONCEPCION AGUILERA; Andrew C Newby
Low tissue inhibitor of metalloproteinases 3 and high matrix metalloproteinase 14 levels defines a subpopulation of highly invasive foam-cell macrophages.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(9):1647-53.
2008: Saima Muzaffar; Nilima Shukla; Mark Bond; G Sala-Newby; Gianni Angelini; Andrew C Newby; Jamie Y Jeremy
Acute inhibition of superoxide formation and Rac1 activation by nitric oxide and iloprost in human vascular smooth muscle cells in response to the thromboxane A2 analogue, U46619.
Prostaglandins, leukotrienes, and essential fatty acids 2008;78(4-5):247-55.
2008: S J White; E D Papadakis; C A Rogers; J L Johnson; Erik A L Biessen; Andrew C Newby
In vitro and in vivo analysis of expression cassettes designed for vascular gene transfer.
Gene therapy 2008;15(5):340-6.
2008: Andrea Caporali; Graciela B Sala-Newby; M Meloni; Gallia Graiani; E Pani; B Cristofaro; Andrew C Newby; Paolo Madeddu; Costanza Emanueli
Identification of the prosurvival activity of nerve growth factor on cardiac myocytes.
Cell death and differentiation 2008;15(2):299-311.
2008: Saima Muzaffar; Nilima Shukla; Mark Bond; Andrew C Newby; Gianni Angelini; Anna Sparatore; Piero Del Soldato; Jamie Y Jeremy
Exogenous hydrogen sulfide inhibits superoxide formation, NOX-1 expression and Rac1 activity in human vascular smooth muscle cells.
Journal of vascular research 2008;45(6):521-8.
2007: Andrew C Newby
Metalloproteinases and vulnerable atherosclerotic plaques.
Trends in cardiovascular medicine 2007;17(8):253-8.
2007: Gavin J Murphy; Andrew C Newby; Jamie Y Jeremy; Andreas Baumbach; Gianni Angelini
A randomized trial of an external Dacron sheath for the prevention of vein graft disease: the Extent study.
The Journal of thoracic and cardiovascular surgery 2007;134(2):504-5.
2007: Mohammed A Majid; Valerie A Smith; Andrew C Newby; Andrew D Dick
Matrix bound SFD mutant TIMP-3 is more stable than wild type TIMP-3.
The British journal of ophthalmology 2007;91(8):1073-6.
2007: Anita C Thomas; Graciela B Sala-Newby; Yasmin Ismail; Jason L Johnson; Gerard Pasterkamp; Andrew C Newby
Genomics of foam cells and nonfoamy macrophages from rabbits identifies arginase-I as a differential regulator of nitric oxide production.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(3):571-7.
2007: Gavin J Murphy; Thomas W Johnson; Martin H Chamberlain; Syed I A Rizvi; Marcie Wyatt; Sarah George; Gianni Angelini; Karl R Karsch; Martin Oberhoff; Andrew C Newby
Short- and long-term effects of cytochalasin D, paclitaxel and rapamycin on wall thickening in experimental porcine vein grafts.
Cardiovascular research 2007;73(3):607-17.
2007: Jamie Y Jeremy; Patricia Gadsdon; Nilima Shukla; Vikram Vijayan; Marcella Wyatt; Andrew C Newby; Gianni Angelini
On the biology of saphenous vein grafts fitted with external synthetic sheaths and stents.
Biomaterials 2007;28(6):895-908.
2006: Andrew C Newby
Do metalloproteinases destabilize vulnerable atherosclerotic plaques?
Current opinion in lipidology 2006;17(5):556-61.
2006: Mohammed A Majid; Valerie A Smith; Fiona J Matthews; Andrew C Newby; Andrew D Dick
Tissue inhibitor of metalloproteinase-3 differentially binds to components of Bruch's membrane.
The British journal of ophthalmology 2006;90(10):1310-5.
2006: Jason L Johnson; Andrew H Baker; Kazuhiro Oka; Lawrence Chan; Andrew C Newby; Christopher L Jackson; Sarah George
Suppression of atherosclerotic plaque progression and instability by tissue inhibitor of metalloproteinase-2: involvement of macrophage migration and apoptosis.
Circulation 2006;113(20):2435-44.
2006: Yih-Jer Wu; Mark Bond; Graciela B Sala-Newby; Andrew C Newby
Altered S-phase kinase-associated protein-2 levels are a major mediator of cyclic nucleotide-induced inhibition of vascular smooth muscle cell proliferation.
Circulation research 2006;98(9):1141-50.
2006: Andrew C Newby
Matrix metalloproteinases regulate migration, proliferation, and death of vascular smooth muscle cells by degrading matrix and non-matrix substrates.
Cardiovascular research 2006;69(3):614-24.
2006: Mark Bond; Graciela B Sala-Newby; Yih-Jer Wu; Andrew C Newby
Biphasic effect of p21Cip1 on smooth muscle cell proliferation: role of PI 3-kinase and Skp2-mediated degradation.
Cardiovascular research 2006;69(1):198-206.
2005: Graciela B Sala-Newby; Sarah George; Mark Bond; Gurtej K Dhoot; Andrew C Newby
Regulation of vascular smooth muscle cell proliferation, migration and death by heparan sulfate 6-O-endosulfatase1.
FEBS letters 2005;579(28):6493-8.
2005: Jason L Johnson; Sarah George; Andrew C Newby; Christopher L Jackson
Divergent effects of matrix metalloproteinases 3, 7, 9, and 12 on atherosclerotic plaque stability in mouse brachiocephalic arteries.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(43):15575-80.
2005: Thomas W Johnson; Yin Xiong Wu; Christian Herdeg; Andreas Baumbach; Andrew C Newby; Karl R Karsch; Martin Oberhoff
Stent-based delivery of tissue inhibitor of metalloproteinase-3 adenovirus inhibits neointimal formation in porcine coronary arteries.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(4):754-9.
2005: Jason Johnson; Kevin Carson; Helen Williams; Sharada Karanam; Andrew C Newby; Gianni Angelini; Sarah George; Christopher Jackson
Plaque rupture after short periods of fat feeding in the apolipoprotein E-knockout mouse: model characterization and effects of pravastatin treatment.
Circulation 2005;111(11):1422-30.
2005: Andrew C Newby
Dual role of matrix metalloproteinases (matrixins) in intimal thickening and atherosclerotic plaque rupture.
Physiological reviews 2005;85(1):1-31.
2004: Mark Bond; Graciela B Sala-Newby; Andrew C Newby
Focal adhesion kinase (FAK)-dependent regulation of S-phase kinase-associated protein-2 (Skp-2) stability. A novel mechanism regulating smooth muscle cell proliferation.
The Journal of biological chemistry 2004;279(36):37304-10.
2004: Sadie C Slater; Evgenia Koutsouki; Christopher L Jackson; Raymond C Bush; Gianni Angelini; Andrew C Newby; Sarah George
R-cadherin:beta-catenin complex and its association with vascular smooth muscle cell proliferation.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(7):1204-10.
2003: Yin-xiong Wu; Thomas Johnson; Christian Herdeg; Andreas Baumbach; Andrew C Newby; Karl K Karsch; Martin Oberhoff
[Stent-based local delivery of therapeutic adenovirus effectively reduces neointimal proliferation in porcine coronaries].
Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 2003;23(12):1263-5.
2003: Graciela B Sala-Newby; Nicola V E Freeman; Maria A Curto; Andrew C Newby
Metabolic and functional consequences of cytosolic 5'-nucleotidase-IA overexpression in neonatal rat cardiomyocytes.
American journal of physiology. Heart and circulatory physiology 2003;285(3):H991-8.
2003: Alex J Chase; Andrew C Newby
Regulation of matrix metalloproteinase (matrixin) genes in blood vessels: a multi-step recruitment model for pathological remodelling.
Journal of vascular research 2003;40(4):329-43.
2003: Elizabeth B Uglow; Sadie C Slater; Graciela B Sala-Newby; CONCEPCION AGUILERA; Gianni Angelini; Andrew C Newby; Sarah George
Dismantling of cadherin-mediated cell-cell contacts modulates smooth muscle cell proliferation.
Circulation research 2003;92(12):1314-21.
2003: CONCEPCION AGUILERA; Sarah George; Jason L Johnson; Andrew C Newby
Relationship between type IV collagen degradation, metalloproteinase activity and smooth muscle cell migration and proliferation in cultured human saphenous vein.
Cardiovascular research 2003;58(3):679-88.
2003: Zhaoxia Luan; Alex J Chase; Andrew C Newby
Statins inhibit secretion of metalloproteinases-1, -2, -3, and -9 from vascular smooth muscle cells and macrophages.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(5):769-75.
2002: Stephen J White; Andrew C Newby
Gene therapy for all aspects of vein-graft disease.
Journal of cardiac surgery 2002;17(6):549-55.
2002: Gianni Angelini; Clinton Lloyd; Ray Bush; Jason Johnson; Andrew C Newby
An external, oversized, porous polyester stent reduces vein graft neointima formation, cholesterol concentration, and vascular cell adhesion molecule 1 expression in cholesterol-fed pigs.
The Journal of thoracic and cardiovascular surgery 2002;124(5):950-6.
2002: Mohammed A Majid; Valerie A Smith; David L Easty; Andrew H Baker; Andrew C Newby
Sorsby's fundus dystrophy mutant tissue inhibitors of metalloproteinase-3 induce apoptosis of retinal pigment epithelial and MCF-7 cells.
FEBS letters 2002;529(2-3):281-5.
2002: Shaista Hussain; Jean W Assender; Mark Bond; Liang-Fong Wong; David Murphy; Andrew C Newby
Activation of protein kinase Czeta is essential for cytokine-induced metalloproteinase-1, -3, and -9 secretion from rabbit smooth muscle cells and inhibits proliferation.
The Journal of biological chemistry 2002;277(30):27345-52.
2002: Martin F Crook; Kay M Southgate; Andrew C Newby
Both ICAM-1- and VCAM-1-integrin interactions are important in mediating monocyte adhesion to human saphenous vein.
Journal of vascular research 2002;39(3):221-9.
2002: Alexander J Chase; Mark Bond; Martin F Crook; Andrew C Newby
Role of nuclear factor-kappa B activation in metalloproteinase-1, -3, and -9 secretion by human macrophages in vitro and rabbit foam cells produced in vivo.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(5):765-71.
2002: Mark Bond; Gillian Murphy; Martin R Bennett; Andrew C Newby; Andrew H Baker
Tissue inhibitor of metalloproteinase-3 induces a Fas-associated death domain-dependent type II apoptotic pathway.
The Journal of biological chemistry 2002;277(16):13787-95.
2002: Mohammed A Majid; Valerie A Smith; David L Easty; Andrew H Baker; Andrew C Newby
Adenovirus mediated gene delivery of tissue inhibitor of metalloproteinases-3 induces death in retinal pigment epithelial cells.
The British journal of ophthalmology 2002;86(1):97-101.
2002: Tanya D Izzard; Christine Taylor; Sonia D Birkett; Christopher L Jackson; Andrew C Newby
Mechanisms underlying maintenance of smooth muscle cell quiescence in rat aorta: role of the cyclin dependent kinases and their inhibitors.
Cardiovascular research 2002;53(1):242-52.
2001: Graciela B Sala-Newby; Andrew C Newby
Cloning of a mouse cytosolic 5'-nucleotidase-I identifies a new gene related to human autoimmune infertility-related protein.
Biochimica et biophysica acta 2001;1521(1-3):12-8.
2001: Mark Bond; A J Chase; Andrew H Baker; Andrew C Newby
Inhibition of transcription factor NF-kappaB reduces matrix metalloproteinase-1, -3 and -9 production by vascular smooth muscle cells.
Cardiovascular research 2001;50(3):556-65.
2001: Sarah George; MOHAMMAD IZZAT; Patricia Gadsdon; Jason Lee Johnson; A P Yim; S Wan; Andrew C Newby; Gianni Angelini; Jamie Y Jeremy
Macro-porosity is necessary for the reduction of neointimal and medial thickening by external stenting of porcine saphenous vein bypass grafts.
Atherosclerosis 2001;155(2):329-36.
2000: Mark Bond; Gillian Murphy; Martin R Bennett; Augustin Amour; Vera Knauper; Andrew C Newby; Andrew H Baker
Localization of the death domain of tissue inhibitor of metalloproteinase-3 to the N terminus. Metalloproteinase inhibition is associated with proapoptotic activity.
The Journal of biological chemistry 2000;275(52):41358-63.
2000: Martin F Crook; Andrew C Newby; Kay M Southgate
Expression of intercellular adhesion molecules in human saphenous veins: effects of inflammatory cytokines and neointima formation in culture.
Atherosclerosis 2000;150(1):33-41.
2000: Graciela B Sala-Newby; N V Freeman; Andrzej Skladanowski; Andrew C Newby
Distinct roles for recombinant cytosolic 5'-nucleotidase-I and -II in AMP and IMP catabolism in COS-7 and H9c2 rat myoblast cell lines.
The Journal of biological chemistry 2000;275(16):11666-71.
2000: Andrew C Newby; AB Zaltsman
Molecular mechanisms in intimal hyperplasia.
The Journal of pathology 2000;190(3):300-9.
2000: Sarah George; Clinton T Lloyd; Gianni Angelini; Andrew C Newby; Andrew H Baker
Inhibition of late vein graft neointima formation in human and porcine models by adenovirus-mediated overexpression of tissue inhibitor of metalloproteinase-3.
Circulation 2000;101(3):296-304.
1999: Andrew C Newby; A H Baker
Targets for gene therapy of vein grafts.
Current opinion in cardiology 1999;14(6):489-94.
1999: Mark Bond; Andrew H Baker; Andrew C Newby
Nuclear factor kappaB activity is essential for matrix metalloproteinase-1 and -3 upregulation in rabbit dermal fibroblasts.
Biochemical and biophysical research communications 1999;264(2):561-7.
1999: Jamie Y Jeremy; D Rowe; AM Emsley; Andrew C Newby
Nitric oxide and the proliferation of vascular smooth muscle cells.
Cardiovascular research 1999;43(3):580-94.
1999: AB Zaltsman; Sarah George; Andrew C Newby
Increased secretion of tissue inhibitors of metalloproteinases 1 and 2 from the aortas of cholesterol fed rabbits partially counterbalances increased metalloproteinase activity.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(7):1700-7.
1999: Kay M Southgate; D Mehta; MOHAMMAD IZZAT; Andrew C Newby; Gianni Angelini
Increased secretion of basement membrane-degrading metalloproteinases in pig saphenous vein into carotid artery interposition grafts.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(7):1640-9.
1999: Graciela B Sala-Newby; Andrzej Skladanowski; Andrew C Newby
The mechanism of adenosine formation in cells. Cloning of cytosolic 5'-nucleotidase-I.
The Journal of biological chemistry 1999;274(25):17789-93.
1999: Andrew H Baker; Sarah George; AB Zaltsman; Gillian Murphy; Andrew C Newby
Inhibition of invasion and induction of apoptotic cell death of cancer cell lines by overexpression of TIMP-3.
British journal of cancer 1999;79(9-10):1347-55.
1999: Andrew C Newby; AB Zaltsman
Fibrous cap formation or destruction--the critical importance of vascular smooth muscle cell proliferation, migration and matrix formation.
Cardiovascular research 1999;41(2):345-60.
1999: A Kranzhöfer; Andrew H Baker; Sarah George; Andrew C Newby
Expression of tissue inhibitor of metalloproteinase-1, -2, and -3 during neointima formation in organ cultures of human saphenous vein.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(2):255-65.
1998: Sarah George; Andrew H Baker; Gianni Angelini; Andrew C Newby
Gene transfer of tissue inhibitor of metalloproteinase-2 inhibits metalloproteinase activity and neointima formation in human saphenous veins.
Gene therapy 1998;5(11):1552-60.
1998: Mark Bond; R P Fabunmi; Andrew H Baker; Andrew C Newby
Synergistic upregulation of metalloproteinase-9 by growth factors and inflammatory cytokines: an absolute requirement for transcription factor NF-kappa B.
FEBS letters 1998;435(1):29-34.
1998: Sarah George; Jason Lee Johnson; Gianni Angelini; Andrew C Newby; Andrew H Baker
Adenovirus-mediated gene transfer of the human TIMP-1 gene inhibits smooth muscle cell migration and neointimal formation in human saphenous vein.
Human gene therapy 1998;9(6):867-77.
1998: Andrew H Baker; AB Zaltsman; Sarah George; Andrew C Newby
Divergent effects of tissue inhibitor of metalloproteinase-1, -2, or -3 overexpression on rat vascular smooth muscle cell invasion, proliferation, and death in vitro. TIMP-3 promotes apoptosis.
The Journal of clinical investigation 1998;101(6):1478-87.
1998: D Mehta; Sarah George; Jamie Y Jeremy; MOHAMMAD IZZAT; Kay M Southgate; A J Bryan; Andrew C Newby; Gianni Angelini
External stenting reduces long-term medial and neointimal thickening and platelet derived growth factor expression in a pig model of arteriovenous bypass grafting.
Nature medicine 1998;4(2):235-9.
1998: Andrzej Skladanowski; Andrew C Newby; Wojciech Makarewicz
Purification and some molecular properties of pigeon heart AMP-selective 5'-nucleotidase.
Advances in experimental medicine and biology 1998;431():113-7.
1997: AB Zaltsman; Andrew C Newby
Increased secretion of gelatinases A and B from the aortas of cholesterol fed rabbits: relationship to lesion severity.
Atherosclerosis 1997;130(1-2):61-70.
1997: Sarah George; AB Zaltsman; Andrew C Newby
Surgical preparative injury and neointima formation increase MMP-9 expression and MMP-2 activation in human saphenous vein.
Cardiovascular research 1997;33(2):447-59.
1996: A H Baker; Gavin W G Wilkinson; R M Hembry; G Murphy; Andrew C Newby
Development of recombinant adenoviruses that drive high level expression of the human metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 and -2 genes: characterization of their infection into rabbit smooth muscle cells and human MCF-7 adenocarcinoma cells.
Matrix biology : journal of the International Society for Matrix Biology 1996;15(6):383-95.
1996: Kay M Southgate; M Fisher; A P Banning; V J Thurston; A H Baker; R P Fabunmi; P H Groves; Malcolm Davies; Andrew C Newby
Upregulation of basement membrane-degrading metalloproteinase secretion after balloon injury of pig carotid arteries.
Circulation research 1996;79(6):1177-87.
1996: Andrew C Newby; Sarah George
Proliferation, migration, matrix turnover, and death of smooth muscle cells in native coronary and vein graft atherosclerosis.
Current opinion in cardiology 1996;11(6):574-82.
1996: MOHAMMAD IZZAT; D Mehta; Alan J Bryan; Barney Reeves; Andrew C Newby; Gianni Angelini
Influence of external stent size on early medial and neointimal thickening in a pig model of saphenous vein bypass grafting.
Circulation 1996;94(7):1741-5.
1996: Gianni Angelini; MOHAMMAD IZZAT; Alan J Bryan; Andrew C Newby
External stenting reduces early medial and neointimal thickening in a pig model of arteriovenous bypass grafting.
The Journal of thoracic and cardiovascular surgery 1996;112(1):79-84.
1996: L M Blayney; P W Gapper; Andrew C Newby
Phospholipase C isoforms in vascular smooth muscle and their regulation by G-proteins.
British journal of pharmacology 1996;118(4):1003-11.
1996: R P Fabunmi; A H Baker; E J Murray; R F Booth; Andrew C Newby
Divergent regulation by growth factors and cytokines of 95 kDa and 72 kDa gelatinases and tissue inhibitors or metalloproteinases-1, -2, and -3 in rabbit aortic smooth muscle cells.
The Biochemical journal 1996;315 ( Pt 1)():335-42.
1996: Sarah George; A Williams; Andrew C Newby
An essential role for platelet-derived growth factor in neointima formation in human saphenous vein in vitro.
Atherosclerosis 1996;120(1-2):227-40.
1995: P H Groves; A P Banning; W J Penny; Malcolm J Lewis; H A Cheadle; Andrew C Newby
Kinetics of smooth muscle cell proliferation and intimal thickening in a pig carotid model of balloon injury.
Atherosclerosis 1995;117(1):83-96.
1995: P H Groves; A P Banning; W J Penny; Andrew C Newby; H A Cheadle; Malcolm J Lewis
The effects of exogenous nitric oxide on smooth muscle cell proliferation following porcine carotid angioplasty.
Cardiovascular research 1995;30(1):87-96.
1995: Andrew C Newby; K Lim; M A Evans; Nicholas P J Brindle; R F Booth
Inhibition of rabbit aortic smooth muscle cell proliferation by selective inhibitors of protein kinase C.
British journal of pharmacology 1995;114(8):1652-6.
1995: Andrew C Newby; R P Fabunmi; Sarah George; Kay M Southgate; A P Banning; V J Thurston; A Williams
Neointimal fibrosis in vascular pathologies: role of growth factors and metalloproteinases in vascular smooth muscle proliferation.
Experimental nephrology 1995;3(2):108-13.
1995: A A Soyombo; Gianni Angelini; Andrew C Newby
Neointima formation is promoted by surgical preparation and inhibited by cyclic nucleotides in human saphenous vein organ cultures.
The Journal of thoracic and cardiovascular surgery 1995;109(1):2-12.
1994: M R Bennett; T D Littlewood; David C Hancock; Gerard I Evan; Andrew C Newby
Down-regulation of the c-myc proto-oncogene in inhibition of vascular smooth-muscle cell proliferation: a signal for growth arrest?
The Biochemical journal 1994;302 ( Pt 3)():701-8.
1994: Sheila E Francis; S Hunter; Cathy M Holt; P A Gadsdon; S Rogers; Gordon W Duff; Andrew C Newby; Gianni Angelini
Release of platelet-derived growth factor activity from pig venous arterial grafts.
The Journal of thoracic and cardiovascular surgery 1994;108(3):540-8.
1994: M R Bennett; Gerard I Evan; Andrew C Newby
Deregulated expression of the c-myc oncogene abolishes inhibition of proliferation of rat vascular smooth muscle cells by serum reduction, interferon-gamma, heparin, and cyclic nucleotide analogues and induces apoptosis.
Circulation research 1994;74(3):525-36.
1994: Andrew C Newby; J W Assender; M A Evans; K Lim; M R Bennett; Gerard I Evan
Transduction pathways for growth stimulatory and inhibitory actions of vasoactive agents.
Experimental nephrology 1994;2(2):94-100.
1994: M R Bennett; S Anglin; J R McEwan; R Jagoe; Andrew C Newby; Gerard I Evan
Inhibition of vascular smooth muscle cell proliferation in vitro and in vivo by c-myc antisense oligodeoxynucleotides.
The Journal of clinical investigation 1994;93(2):820-8.
1994: Andrew C Newby; Kay M Southgate; Malcolm Davies
Extracellular matrix degrading metalloproteinases in the pathogenesis of arteriosclerosis.
Basic research in cardiology 1994;89 Suppl 1():59-70.
1993: A A Soyombo; V J Thurston; Andrew C Newby
Endothelial control of vascular smooth muscle proliferation in an organ culture of human saphenous vein.
European heart journal 1993;14 Suppl I():201-6.
1993: A A Soyombo; Gianni Angelini; A J Bryan; Andrew C Newby
Surgical preparation induces injury and promotes smooth muscle cell proliferation in a culture of human saphenous vein.
Cardiovascular research 1993;27(11):1961-7.
1993: Andrew C Newby; Sarah George
Proposed roles for growth factors in mediating smooth muscle proliferation in vascular pathologies.
Cardiovascular research 1993;27(7):1173-83.
1993: Cathy M Holt; Sheila E Francis; Andrew C Newby; S Rogers; P A Gadsdon; T Taylor; Gianni Angelini
Comparison of response to injury in organ culture of human saphenous vein and internal mammary artery.
The Annals of thoracic surgery 1993;55(6):1522-8.
1993: A G Violaris; Andrew C Newby; Gianni Angelini
Effects of external stenting on wall thickening in arteriovenous bypass grafts.
The Annals of thoracic surgery 1993;55(3):667-71.
1992: Cathy M Holt; Sheila E Francis; S Rogers; P A Gadsdon; T Taylor; C Clelland; A Soyombo; Andrew C Newby; Gianni Angelini
Intimal proliferation in an organ culture of human internal mammary artery.
Cardiovascular research 1992;26(12):1189-94.
1992: J W Assender; Kay M Southgate; Maurice B Hallett; Andrew C Newby
Inhibition of proliferation, but not of Ca2+ mobilization, by cyclic AMP and GMP in rabbit aortic smooth-muscle cells.
The Biochemical journal 1992;288 ( Pt 2)():527-32.
1992: Kay M Southgate; Malcolm Davies; R F Booth; Andrew C Newby
Involvement of extracellular-matrix-degrading metalloproteinases in rabbit aortic smooth-muscle cell proliferation.
The Biochemical journal 1992;288 ( Pt 1)():93-9.
1992: Andrew C Newby; Kay M Southgate; J W Assender
Inhibition of vascular smooth muscle cell proliferation by endothelium-dependent vasodilators.
Herz 1992;17(5):291-9.
1992: Gianni Angelini; A J Bryan; H M Williams; A A Soyombo; A Williams; J Tovey; Andrew C Newby
Time-course of medial and intimal thickening in pig venous arterial grafts: relationship to endothelial injury and cholesterol accumulation.
The Journal of thoracic and cardiovascular surgery 1992;103(6):1093-103.
1992: Gianni Angelini; Alan J Bryan; S Hunter; Andrew C Newby
A surgical technique that preserves human saphenous vein functional integrity.
The Annals of thoracic surgery 1992;53(5):871-4.
1992: L M Blayney; P W Gapper; Andrew C Newby
Vasoconstrictor agonists activate G-protein-dependent receptor-operated calcium channels in pig aortic microsomes.
The Biochemical journal 1992;282 ( Pt 1)():81-4.
1992: L M Blayney; P W Gapper; Andrew C Newby
Vasoconstrictor agonists activate G-protein dependent receptor operated calcium channels (ROCs) in pig aortic microsomes.
Biochemical Society transactions 1992;20(1):16S.
1991: J P Cooper; Andrew C Newby
Monocyte adhesion to human saphenous vein in vitro.
Atherosclerosis 1991;91(1-2):85-95.
1991: Gianni Angelini; A A Soyombo; Andrew C Newby
Winner of the ESVS prize 1990. Smooth muscle cell proliferation in response to injury in an organ culture of human saphenous vein.
European journal of vascular surgery 1991;5(1):5-12.
1991: L M Blayney; P W Gapper; Andrew C Newby
Inhibition of a receptor-operated calcium channel in pig aortic microsomes by cyclic GMP-dependent protein kinase.
The Biochemical journal 1991;273 ( Pt 3)():803-6.
1991: Andrew C Newby
Adenosine: origin and clinical roles.
Advances in experimental medicine and biology 1991;309A():265-70.
1990: A A Soyombo; Gianni Angelini; A J Bryan; B Jasani; Andrew C Newby
Intimal proliferation in an organ culture of human saphenous vein.
The American journal of pathology 1990;137(6):1401-10.
1990: Andrew C Newby; R O Morgan; L M Blayney
Inhibition of platelet membrane hormone-transducing GTPases by cyclic GMP-dependent protein kinase.
Biochemical Society transactions 1990;18(3):477-8.
1990: L M Blayney; P W Gapper; Andrew C Newby
Inhibition by cyclic GMP-dependent protein kinase of a histamine- and guanyl nucleotide-induced calcium permeability in pig aortic microsomes.
Biochemical Society transactions 1990;18(3):479-80.
1990: A C Skladanowski; Andrew C Newby
Partial purification and properties of an AMP-specific soluble 5'-nucleotidase from pigeon heart.
The Biochemical journal 1990;268(1):117-22.
1990: Kay M Southgate; Andrew C Newby
Serum-induced proliferation of rabbit aortic smooth muscle cells from the contractile state is inhibited by 8-Br-cAMP but not 8-Br-cGMP.
Atherosclerosis 1990;82(1-2):113-23.
1990: L M Blayney; Andrew C Newby
Histamine and a guanine nucleotide increase calcium permeability in pig aortic microsomal fractions.
The Biochemical journal 1990;267(1):105-9.
1990: Gianni Angelini; A J Bryan; H M Williams; R Morgan; Andrew C Newby
Distention promotes platelet and leukocyte adhesion and reduces short-term patency in pig arteriovenous bypass grafts.
The Journal of thoracic and cardiovascular surgery 1990;99(3):433-9.
1990: Andrew C Newby; A H Henderson
Stimulus-secretion coupling in vascular endothelial cells.
Annual review of physiology 1990;52():661-74.
1989: L M Blayney; Andrew C Newby
Calcium permeability of pig aortic microsomes is increased by histamine and a guanyl nucleotide.
British journal of pharmacology 1989;98 Suppl():791P.
1989: Gianni Angelini; A J Bryan; Robert R West; Andrew C Newby; I M Breckenridge
Coronary artery bypass surgery: current practice in the United Kingdom.
Thorax 1989;44(9):721-4.
1989: A C Skladanowski; G B Sala; Andrew C Newby
Inhibition of IMP-specific cytosolic 5'-nucleotidase and adenosine formation in rat polymorphonuclear leucocytes by 5'-deoxy-5'-isobutylthio derivatives of adenosine and inosine.
The Biochemical journal 1989;262(1):203-8.
1989: Gianni Angelini; Andrew C Newby
The future of saphenous vein as a coronary artery bypass conduit.
European heart journal 1989;10(3):273-80.
1989: R O Morgan; Andrew C Newby
Nitroprusside differentially inhibits ADP-stimulated calcium influx and mobilization in human platelets.
The Biochemical journal 1989;258(2):447-54.
1988: Andrew C Newby
Metabolic vasodilatation: the role of adenosine.
Biochemical Society transactions 1988;16(4):479-80.
1988: Andrew C Newby
The pigeon heart 5'-nucleotidase responsible for ischaemia-induced adenosine formation.
The Biochemical journal 1988;253(1):123-30.
1988: P Meghji; K M Middleton; Andrew C Newby
Absolute rates of adenosine formation during ischaemia in rat and pigeon hearts.
The Biochemical journal 1988;249(3):695-703.
1988: P Meghji; K Middleton; C J Hassall; M I Phillips; Andrew C Newby
Evidence for extracellular deamination of adenosine in the rat heart.
The International journal of biochemistry 1988;20(12):1335-41.
1988: S L Passani; Gianni Angelini; I M Breckenridge; Andrew C Newby
Endothelial function can be preserved during cryo-storage of human saphenous vein.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 1988;2(4):233-6.
1987: Gianni Angelini; S L Passani; I M Breckenridge; Andrew C Newby
Nature and pressure dependence of damage induced by distension of human saphenous vein coronary artery bypass grafts.
Cardiovascular research 1987;21(12):902-7.
1987: Gianni Angelini; I M Breckenridge; H M Williams; Andrew C Newby
A surgical preparative technique for coronary bypass grafts of human saphenous vein which preserves medial and endothelial functional integrity.
The Journal of thoracic and cardiovascular surgery 1987;94(3):393-8.
1987: Gianni Angelini; I M Breckenridge; J V Psaila; H M Williams; A H Henderson; Andrew C Newby
Preparation of human saphenous vein for coronary artery bypass grafting impairs its capacity to produce prostacyclin.
Cardiovascular research 1987;21(1):28-33.
1985: Gianni Angelini; I M Breckenridge; Eric G Butchart; S H Armistead; K M Middleton; A H Henderson; Andrew C Newby
Metabolic damage to human saphenous vein during preparation for coronary artery bypass grafting.
Cardiovascular research 1985;19(6):326-34.