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David Newby

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Alison C Mackinnon; Mark R Miller; David E Newby; Patrick Wf Hadoke; Xiaojun Liu; Tariq Sethi
Inhibition of galectin-3 reduces atherosclerosis in apolipoprotein E-deficient mice.
Gareth J Padfield; Olga Tura-Ceide; Marc Turner; George Robin Barclay; Elizabeth Freyer; David E Newby; Nicholas L Mills
Endothelial progenitor cells, atheroma burden and clinical outcome in patients with coronary artery disease.
Andrew J Lucking; Christopher A Ludlam; Elspeth E Paterson; Nicholas A Boon; Dana Faratian; Keith A A Fox; Kyle R Gibson; David E Newby
Endogenous tissue plasminogen activator enhances fibrinolysis and limits thrombus formation in a clinical model of thrombosis.

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2013: Alison C Mackinnon; Mark R Miller; David E Newby; Patrick Wf Hadoke; Xiaojun Liu; Tariq Sethi
Inhibition of galectin-3 reduces atherosclerosis in apolipoprotein E-deficient mice.
Glycobiology 2013;23(6):654-63.
2013: Gareth J Padfield; Olga Tura-Ceide; Marc Turner; George Robin Barclay; Elizabeth Freyer; David E Newby; Nicholas L Mills
Endothelial progenitor cells, atheroma burden and clinical outcome in patients with coronary artery disease.
Heart (British Cardiac Society) 2013;99(11):791-8.
2013: Andrew J Lucking; Christopher A Ludlam; Elspeth E Paterson; Nicholas A Boon; Dana Faratian; Keith A A Fox; Kyle R Gibson; David E Newby
Endogenous tissue plasminogen activator enhances fibrinolysis and limits thrombus formation in a clinical model of thrombosis.
Arteriosclerosis, thrombosis, and vascular biology 2013;33(5):1105-11.
2013: Anne Jones; Graham McKillop; David E Newby; Martin Connell; Neil J Douglas; Marjorie Vennelle; Renata L Riha
Arterial stiffness and endothelial function in obstructive sleep apnoea/hypopnoea syndrome.
Sleep medicine 2013;14(5):428-32.
2013: Ken Donaldson; Rodger Duffin; Jeremy P Langrish; Mark R Miller; Nicholas L Mills; Craig A Poland; Jennifer Raftis; Anoop Shah; Catherine A Shaw; David E Newby
Nanoparticles and the cardiovascular system: a critical review.
Nanomedicine (London, England) 2013;8(3):403-23.
2013: Alan G Japp; Arie Katz; Ninian N Lang; Xu Meng; David Burt; Raj Chelliah; Thomas M Connolly; Giora Z Feuerstein; Keith A A Fox; Laura Tattersall; Kathleen Weisel; David E Newby
Effect of PSI-697, a novel P-selectin inhibitor, on platelet-monocyte aggregate formation in humans.
Journal of the American Heart Association 2013;2(1):e006007.
2013: Jeremy P Langrish; Ian L Megson; Stefan Barath; Scott Blackwell; Anders Blomberg; Jenny Bosson; Ala Muala; David E Newby; Jamshid Pourazar; Thomas Sandström; Stefan Söderberg; Andrew Treweeke; Jon Unosson; Nicholas L Mills
Altered nitric oxide bioavailability contributes to diesel exhaust inhalation-induced cardiovascular dysfunction in man.
Journal of the American Heart Association 2013;2(1):e004309.
2013: Sowmya Venkatasubramanian; Megan E Griffiths; Ninian N Lang; Rosa Luo; Steven G McLean; Mark R Miller; David E Newby
Vascular effects of urocortins 2 and 3 in healthy volunteers.
Journal of the American Heart Association 2013;2(1):e004267.
2013: Jehangir N Din; Andrew D Flapan; Scott A Harding; Karin Lyall; Rachel M Archer; Jaydeep Sarma; David E Newby
Effect of ω-3 fatty acid supplementation on endothelial function, endogenous fibrinolysis and platelet activation in male cigarette smokers.
Heart (British Cardiac Society) 2013;99(3):168-74.
2013: Olga Tura; Marc L Turner; David E Newby; Kay Samuel; Elizabeth M Skinner; G Robin Barclay; Mairi Brittan; Ronald C J Gallagher; Patrick W F Hadoke; Nicholas L Mills
Late outgrowth endothelial cells resemble mature endothelial cells and are not derived from bone marrow.
Stem cells (Dayton, Ohio) 2013;31(2):338-48.
2013: Daniel F Mackay; Alex McConnachie; David E Newby; Sally Haw; Peter Langhorne; Suzanne M Lloyd; Jill P Pell
Impact of Scotland's Comprehensive, Smoke-Free Legislation on Stroke.
PloS one 2013;8(5):e62597.
2013: Shruti Daga; Dana K Dawson; J Ross Fitzgerald; Rachel K Y Hung; Gareth J Padfield; James G Shepherd; J Garreth S Callaghan; David E Newby
GPIb VNTR C/C genotype may predict embolic events in infective endocarditis.
The Journal of heart valve disease 2013;22(1):133-41.
2013: Michelle C Williams; Neal G Uren; Nicholas L M Cruden; David E Newby
A low-dose comprehensive cardiac CT protocol assessing anatomy, function, perfusion, and viability.
Journal of cardiovascular computed tomography 2013;7(1):69-72.
2013: Marc R Dweck; Nikhil V Joshi; James H F Rudd; David E Newby
Imaging of inflammation and calcification in aortic stenosis.
Current cardiology reports 2013;15(1):320.
2012: Marc R Dweck; Nicholas A Boon; David E Newby
Calcific aortic stenosis: a disease of the valve and the myocardium.
Journal of the American College of Cardiology 2012;60(19):1854-63.
2012: Marc R Dweck; Francis R Joshi; David E Newby; James Rudd
Noninvasive imaging in cardiovascular therapy: the promise of coronary arterial ¹⁸F-sodium fluoride uptake as a marker of plaque biology.
Expert review of cardiovascular therapy 2012;10(9):1075-7.
2012: N N Lang; David E Newby
Cardiac compression causing fatal acute ST-segment elevation myocardial infarction.
QJM : monthly journal of the Association of Physicians 2012;105(9):883-5.
2012: Christian M Pedersen; Michael R Schmidt; Gareth Barnes; Hans Erik Bøtker; Rajesh K Kharbanda; David E Newby; Nicholas L M Cruden
Ischaemia-reperfusion injury impairs tissue plasminogen activator release in man.
European heart journal 2012;33(15):1920-7.
2012: David A McAllister; Lawrence McAlpine; Nicholas L Mills; David E Newby; Jennifer O'Connor; Philip Reid; Ross Carruthers; George Chalmers; Elaine Clark; Andrew Leitch; Peter W Macfarlane; John D Maclay; William MacNee
Diagnosis of myocardial infarction following hospitalisation for exacerbation of COPD.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2012;39(5):1097-103.
2012: Marc R Dweck; Alison M Fletcher; Charlotte Jones; Nikhil V Joshi; Graham McKillop; Hamish Richardson; James Rudd; Edwin J R Van Beek; Audrey White; Michelle C Williams; Nicholas A Boon; Marcus W L Chow; David E Newby
Coronary arterial 18F-sodium fluoride uptake: a novel marker of plaque biology.
Journal of the American College of Cardiology 2012;59(17):1539-48.
2012: Shirjel R Alam; David E Newby; Peter A Henriksen
Role of the endogenous elastase inhibitor, elafin, in cardiovascular injury: from epithelium to endothelium.
Biochemical pharmacology 2012;83(6):695-704.
2012: Jeremy P Langrish; Matthew M Y Lee; Jing Li; Liming Li; Xi Li; Mark R Miller; Nicholas L Mills; David E Newby; Shengfeng Wang; Gareth D Barnes; Nicholas A Boon; Flemming R Cassee; Ken Donaldson; Lixin Jiang
Reducing personal exposure to particulate air pollution improves cardiovascular health in patients with coronary heart disease.
Environmental health perspectives 2012;120(3):367-72.
2012: Nicholas L M Cruden; Keith A A Fox; Ninian N Lang; Thomas J MacGillivray; Neal G Uren; David E Newby
Vasomotor and fibrinolytic responses to kinin receptor agonists in the atherosclerotic human lower limb.
Heart and vessels 2012;27(2):179-85.
2012: Marc R Dweck; Ankur Gulati; Andrew Jabbour; Sanjiv Joshi; Philip Kilner; Alicia M Maceira; Raad H Mohiaddin; Timothy Murigu; David E Newby; David B Northridge; Dudley J Pennell; John Pepper; Francisco Alpendurada; Nicholas A Boon; Stuart A Cook; Isabelle Roussin; Sanjay K Prasad
Left ventricular remodeling and hypertrophy in patients with aortic stenosis: insights from cardiovascular magnetic resonance.
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 2012;14():50.
2012: Melissa Cudmore; Takeshi Fujisawa; Yuchun Gu; Peter W Hewett; Bin Ma; Mark R Miller; David E Newby; Wenda Ramma; Samir Sissaoui; Ke-Qing Wang; Herbert Weich; Shakil Ahmad; Bahjat Al-Ani; Bernhard Barleon; Meng Cai; Asif Ahmed
The role of heterodimerization between VEGFR-1 and VEGFR-2 in the regulation of endothelial cell homeostasis.
Nature communications 2012;3():972.
2012: Sarah Robertson; Catherine A Shaw; David E Newby; Rodger Duffin; Gillian A Gray; Patrick W F Hadoke; Steven G McLean; Mark R Miller
Diesel exhaust particulate induces pulmonary and systemic inflammation in rats without impairing endothelial function ex vivo or in vivo.
Particle and fibre toxicology 2012;9():9.
2012: Nicholas L Mills; Mary Stoddart; Simon Walker; Antonia M D Churchhouse; Martin A Denvir; Keith A A Fox; Kuan Ken Lee; Margaret MacLeod; David A McAllister; David E Newby
Implications of lowering threshold of plasma troponin concentration in diagnosis of myocardial infarction: cohort study.
BMJ (Clinical research ed.) 2012;344():e1533.
2011: Michael J Thrippleton; Alistair R Williams; Mark E Bastin; Maurits A Jansen; Ian Marshall; Graham McKillop; Gavin D Merrifield; Kirsty I Munro; David E Newby; Anca Oniscu; Scott I Semple; Hilary O Critchley
Ex vivo water diffusion tensor properties of the fibroid uterus at 7 T and their relation to tissue morphology.
Journal of magnetic resonance imaging : JMRI 2011;34(6):1445-51.
2011: Ninian N Lang; Ingibjörg J Guðmundsdóttir; David E Newby
Vascular PAR-1: activity and antagonism.
Cardiovascular therapeutics 2011;29(6):349-61.
2011: Nicholas L Mills; Thomas Sandstrom; Jon Beveridge; Anders Blomberg; john boere; Nicholas A Boon; Flemming R Cassee; Ken Donaldson; Rodger Duffin; Laura Flint; Paul H B Fokkens; Patrick W F Hadoke; Andrew J Lucking; Mark R Miller; David E Newby
Combustion-derived nanoparticulate induces the adverse vascular effects of diesel exhaust inhalation.
European heart journal 2011;32(21):2660-71.
2011: Marc R Dweck; Ankur Gulati; Andrew Jabbour; Sanjiv Joshi; Philip J Kilner; Giovanni Melina; Raad H Mohiaddin; Timothy Murigu; David E Newby; Dudley J Pennell; John Pepper; Nishant A Prasad; Francisco Alpendurada; Emiliano Angeloni; Winston Banya; Stuart A Cook; Cesare Quarto; Sadaf Raza; Simone Refice; Isabelle Roussin; Mary Sheppard; Rick Wage; Sanjay K Prasad
Midwall fibrosis is an independent predictor of mortality in patients with aortic stenosis.
Journal of the American College of Cardiology 2011;58(12):1271-9.
2011: John D Maclay; Andrew Deans; Shonna Johnston; David A McAllister; Catherine McGuinnes; Nicholas L Mills; David E Newby; Jennifer Raftis; William MacNee
Increased platelet activation in patients with stable and acute exacerbation of COPD.
Thorax 2011;66(9):769-74.
2011: Matthew Reed; Sarah S Henderson; David E Newby; Alasdair J Gray
One-year prognosis after syncope and the failure of the ROSE decision instrument to predict one-year adverse events.
Annals of emergency medicine 2011;58(3):250-6.
2011: M C Williams; G McKillop; J H Reid; Neal G Uren; Edwin J.R. van Beek; N W Weir; David E Newby
Cardiac and coronary CT comprehensive imaging approach in the assessment of coronary heart disease.
Heart (British Cardiac Society) 2011;97(15):1198-205.
2011: Catherine A Shaw; Caroline M Tabor; Ken Donaldson; Rodger Duffin; Mark R Miller; David E Newby; Sarah Robertson; Patrick W F Hadoke
Diesel exhaust particulate--exposed macrophages cause marked endothelial cell activation.
American journal of respiratory cell and molecular biology 2011;44(6):840-51.
2011: Jennifer M J Richards; Scott I Semple; Thomas J MacGillivray; Calum Gray; Jeremy P Langrish; Michelle Williams; Marc Dweck; William Wallace; Graham McKillop; Roderick T A Chalmers; O James Garden; David E Newby
Abdominal aortic aneurysm growth predicted by uptake of ultrasmall superparamagnetic particles of iron oxide: a pilot study.
Circulation. Cardiovascular imaging 2011;4(3):274-81.
2011: Andrew J Lucking; Magnus Lundbäck; Stefan L Barath; Nicholas L Mills; Manjit K Sidhu; Jeremy P Langrish; Nicholas A Boon; Jamshid Pourazar; Juan J Badimon; Miriam E Gerlofs-Nijland; Flemming R Cassee; Christoffer Boman; Kenneth Donaldson; Thomas Sandstrom; David E Newby; Anders Blomberg
Particle traps prevent adverse vascular and prothrombotic effects of diesel engine exhaust inhalation in men.
Circulation 2011;123(16):1721-8.
2011: Nicholas L Mills; Alexander E Finlayson; Manuel C Gonzalez; Håkan Törnqvist; Stefan Barath; Elen Vink; Colin Goudie; Jeremy P Langrish; Stefan Söderberg; Nicholas A Boon; Keith A A Fox; Ken Donaldson; Thomas Sandström; Anders Blomberg; David E Newby
Diesel exhaust inhalation does not affect heart rhythm or heart rate variability.
Heart (British Cardiac Society) 2011;97(7):544-50.
2011: Nicholas L Mills; Antonia M D Churchhouse; Kuan Ken Lee; Atul Anand; David Gamble; Anoop S V Shah; Elspeth Paterson; Margaret MacLeod; Catriona Graham; Simon Walker; Martin A Denvir; Keith A A Fox; David E Newby
Implementation of a sensitive troponin I assay and risk of recurrent myocardial infarction and death in patients with suspected acute coronary syndrome.
JAMA : the journal of the American Medical Association 2011;305(12):1210-6.
2011: Shruti Daga; James G Shepherd; J Garreth S Callaghan; Rachel K Y Hung; Dana K Dawson; Gareth J Padfield; Shi Y Hey; Robyn A Cartwright; David E Newby; J Ross Fitzgerald
Platelet receptor polymorphisms do not influence Staphylococcus aureus-platelet interactions or infective endocarditis.
Microbes and infection / Institut Pasteur 2011;13(3):216-25.
2011: Catherine McGuinnes; Rodger Duffin; Simon Brown; Nicholas L Mills; Ian L Megson; William MacNee; Shonna Johnston; Sen Lin Lu; Lang Tran; Rufia Li; Xue Wang; David E Newby; Ken Donaldson
Surface derivatization state of polystyrene latex nanoparticles determines both their potency and their mechanism of causing human platelet aggregation in vitro.
Toxicological sciences : an official journal of the Society of Toxicology 2011;119(2):359-68.
2011: C M Pedersen; Nicholas L M Cruden; M R Schmidt; C Lau; H E Bøtker; R K Kharbanda; David E Newby
Remote ischemic preconditioning prevents systemic platelet activation associated with ischemia-reperfusion injury in humans.
Journal of thrombosis and haemostasis : JTH 2011;9(2):404-7.
2011: Jehangir N Din; S M Aftab; A W Jubb; F H Carnegy; Karin Lyall; Jaydeep Sarma; David E Newby; Andrew D Flapan
Effect of moderate walnut consumption on lipid profile, arterial stiffness and platelet activation in humans.
European journal of clinical nutrition 2011;65(2):234-9.
2010: Anoop S V Shah; David E Newby; Nicholas L Mills
Potential link between ozone and recurrent stroke.
Heart (British Cardiac Society) 2010;96(24):1953-4.
2010: Andrew J Lucking; Rajesh Chelliah; Alexander D Trotman; Thomas M Connolly; Giora Z Feuerstein; Keith A Fox; Nicholas A Boon; Juan J Badimon; David E Newby
Characterisation and reproducibility of a human ex vivo model of thrombosis.
Thrombosis research 2010;126(5):431-5.
2010: Anne Burdess; Alastair F Nimmo; Neil Campbell; Scott A Harding; O J Garden; A Raymond Dawson; David E Newby
Perioperative platelet and monocyte activation in patients with critical limb ischemia.
Journal of vascular surgery 2010;52(3):697-703.
2010: David E Newby
Triggering of acute myocardial infarction: beyond the vulnerable plaque.
Heart (British Cardiac Society) 2010;96(15):1247-51.
2010: Sowmya Venkatasubramanian; David E Newby; Ninian N Lang
Urocortins in heart failure.
Biochemical pharmacology 2010;80(3):289-96.
2010: Gareth Barnes; Alan G Japp; David E Newby
Translational promise of the apelin--APJ system.
Heart (British Cardiac Society) 2010;96(13):1011-6.
2010: Anne Burdess; Alastair F Nimmo; O James Garden; John A Murie; A R W Dawson; Keith A A Fox; David E Newby
Randomized controlled trial of dual antiplatelet therapy in patients undergoing surgery for critical limb ischemia.
Annals of surgery 2010;252(1):37-42.
2010: Nicholas L M Cruden; Scott A Harding; Andrew D Flapan; Cat Graham; Sarah H Wild; Rachel Slack; Jill P Pell; David E Newby
Previous coronary stent implantation and cardiac events in patients undergoing noncardiac surgery.
Circulation. Cardiovascular interventions 2010;3(3):236-42.
2010: Gareth J Padfield; Olga Tura; Marlieke L A Haeck; Abigail Short; Elizabeth Freyer; G Robin Barclay; David E Newby; Nicholas L Mills
Circulating endothelial progenitor cells are not affected by acute systemic inflammation.
American journal of physiology. Heart and circulatory physiology 2010;298(6):H2054-61.
2010: A J Lucking; A Visvanathan; H Philippou; S Fraser; P J Grant; T M Connolly; S J Gardell; G Z Feuerstein; K A A Fox; N A Booth; David E Newby
Effect of the small molecule plasminogen activator inhibitor-1 (PAI-1) inhibitor, PAI-749, in clinical models of fibrinolysis.
Journal of thrombosis and haemostasis : JTH 2010;8(6):1333-9.
2010: A G Japp; Nicholas L M Cruden; G Barnes; N van Gemeren; J Mathews; J Adamson; Neil R Johnston; Martin A Denvir; Ian L Megson; Andrew D Flapan; David E Newby
Acute cardiovascular effects of apelin in humans: potential role in patients with chronic heart failure.
Circulation 2010;121(16):1818-27.
2010: Gareth J Padfield; David E Newby; Nicholas L Mills
Understanding the role of endothelial progenitor cells in percutaneous coronary intervention.
Journal of the American College of Cardiology 2010;55(15):1553-65.
2010: Matthew Reed; David E Newby; Andrew J Coull; Robin J Prescott; Alasdair J Gray
Diagnostic and prognostic utility of troponin estimation in patients presenting with syncope: a prospective cohort study.
Emergency medicine journal : EMJ 2010;27(4):272-6.
2010: Rebecca M Reynolds; Brian R Walker; Sally Haw; David E Newby; Daniel F Mackay; Stuart M Cobbe; Alastair C H Pell; Colin Fischbacher; Stuart Pringle; David Murdoch; Frank Dunn; Keith Oldroyd; Paul Macintyre; Brian O'Rourke; Jill P Pell
Low serum cortisol predicts early death after acute myocardial infarction.
Critical care medicine 2010;38(3):973-5.
2010: Matthew Reed; David E Newby; Andrew J Coull; Robin J Prescott; Keith G Jacques; Alasdair J Gray
The ROSE (risk stratification of syncope in the emergency department) study.
Journal of the American College of Cardiology 2010;55(8):713-21.
2010: A O Robb; Jehangir N Din; Nicholas L Mills; I B J Smith; A Blomberg; M N L Zikry; J B Raftis; David E Newby; Fiona C Denison
The influence of the menstrual cycle, normal pregnancy and pre-eclampsia on platelet activation.
Thrombosis and haemostasis 2010;103(2):372-8.
2010: Jeremy P Langrish; Magnus Lundbäck; Stefan Barath; Stefan Söderberg; Nicholas L Mills; David E Newby; Thomas Sandström; Anders Blomberg
Exposure to nitrogen dioxide is not associated with vascular dysfunction in man.
Inhalation toxicology 2010;22(3):192-8.
2009: Nicholas L Mills; O Tura; G J Padfield; C Millar; N N Lang; David Stirling; Christopher A Ludlam; M L Turner; G R Barclay; David E Newby
Dissociation of phenotypic and functional endothelial progenitor cells in patients undergoing percutaneous coronary intervention.
Heart (British Cardiac Society) 2009;95(24):2003-8.
2009: R Chelliah; A J Lucking; L Tattersall; S Daga; N J Beresford-Cleary; K Cortas; K A A Fox; G Z Feuerstein; T M Connolly; David E Newby
P-selectin antagonism reduces thrombus formation in humans.
Journal of thrombosis and haemostasis : JTH 2009;7(11):1915-9.
2009: Jeremy P Langrish; Nicholas L Mills; David E Newby
Heat and haze: a forecast for myocardial infarction?
Heart (British Cardiac Society) 2009;95(21):1721-2.
2009: Camilla J Stockley; Matthew Reed; David E Newby; Andrew J Coull; Gareth Clegg; Alasdair J Gray
The utility of routine D-dimer measurement in syncope.
European journal of emergency medicine : official journal of the European Society for Emergency Medicine 2009;16(5):256-60.
2009: Jeremy P Langrish; Magnus Lundbäck; Nicholas L Mills; Neil R Johnston; David J Webb; Thomas Sandström; Anders Blomberg; David E Newby
Contribution of endothelin 1 to the vascular effects of diesel exhaust inhalation in humans.
Hypertension 2009;54(4):910-5.
2009: John D Maclay; David A McAllister; Nicholas L Mills; Finny P Paterson; Christopher A Ludlam; Ellen M Drost; David E Newby; William MacNee
Vascular dysfunction in chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine 2009;180(6):513-20.
2009: Alasdair J Gray; Steven Goodacre; David E Newby; M A Masson; F Sampson; S Dixon; S Crane; M Elliott; Jon P Nicholl
A multicentre randomised controlled trial of the use of continuous positive airway pressure and non-invasive positive pressure ventilation in the early treatment of patients presenting to the emergency department with severe acute cardiogenic pulmonary oedema: the 3CPO trial.
Health technology assessment (Winchester, England) 2009;13(33):1-106.
2009: Rebecca M Reynolds; B Ilyas; J F Price; F G R Fowkes; David E Newby; David J Webb; Brian R Walker
Circulating plasma cortisol concentrations are not associated with coronary artery disease or peripheral vascular disease.
QJM : monthly journal of the Association of Physicians 2009;102(7):469-75.
2009: Amy O Robb; Nicholas L Mills; Jehangir N Din; Imogen B J Smith; Finny Paterson; David E Newby; Fiona C Denison
Influence of the menstrual cycle, pregnancy, and preeclampsia on arterial stiffness.
Hypertension 2009;53(6):952-8.
2009: Jeremy P Langrish; Nicholas L Mills; Louise E Bath; Pamela Warner; David J Webb; C J H Kelnar; Hilary Critchley; David E Newby; W Hamish B Wallace
Cardiovascular effects of physiological and standard sex steroid replacement regimens in premature ovarian failure.
Hypertension 2009;53(5):805-11.
2009: Mark R Miller; Stephen J Borthwick; Catherine A Shaw; Steven G McLean; Daniel McClure; Nicholas L Mills; Rodger Duffin; Ken Donaldson; Ian L Megson; Patrick W F Hadoke; David E Newby
Direct impairment of vascular function by diesel exhaust particulate through reduced bioavailability of endothelium-derived nitric oxide induced by superoxide free radicals.
Environmental health perspectives 2009;117(4):611-6.
2009: B Ilyas; Neeraj Dhaun; D Markie; P Stansell; Jane Goddard; David E Newby; David J Webb
Renal function is associated with arterial stiffness and predicts outcome in patients with coronary artery disease.
QJM : monthly journal of the Association of Physicians 2009;102(3):183-91.
2009: A O Robb; Nicholas L Mills; I B J Smith; A Short; O Tura-Ceide; G R Barclay; A Blomberg; Hilary Critchley; David E Newby; Fiona C Denison
Influence of menstrual cycle on circulating endothelial progenitor cells.
Human reproduction (Oxford, England) 2009;24(3):619-25.
2009: Jeremy P Langrish; Nicholas L Mills; Julian Kk Chan; Daan L A C Leseman; Robert J Aitken; Paul H B Fokkens; Flemming R Cassee; Jing Li; Ken Donaldson; David E Newby; Lixin Jiang
Beneficial cardiovascular effects of reducing exposure to particulate air pollution with a simple facemask.
Particle and fibre toxicology 2009;6():8.
2009: Magnus Lundbäck; Nicholas L Mills; Andrew Lucking; Stefan Barath; Ken Donaldson; David E Newby; Thomas Sandström; Anders Blomberg
Experimental exposure to diesel exhaust increases arterial stiffness in man.
Particle and fibre toxicology 2009;6():7.
2008: Norma C McAvoy; Narendra Kochar; Graham McKillop; David E Newby; Peter C Hayes
Prevalence of coronary artery calcification in patients undergoing assessment for orthotopic liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2008;14(12):1725-31.
2008: Ninian N Lang; Rachel C Myles; Francis L Burton; David P Hall; Yi Zia Chin; Nicholas A Boon; David E Newby
The vascular effects of rotigaptide in vivo in man.
Biochemical pharmacology 2008;76(10):1194-200.
2008: Alan G Japp; Nicholas L M Cruden; David A B Amer; Vivienne K Y Li; Ewan B Goudie; Neil R Johnston; Sushma Sharma; Ilene Neilson; David J Webb; Ian L Megson; Andrew D Flapan; David E Newby
Vascular effects of apelin in vivo in man.
Journal of the American College of Cardiology 2008;52(11):908-13.
2008: Nicholas L M Cruden; David E Newby
Therapeutic potential of icatibant (HOE-140, JE-049).
Expert opinion on pharmacotherapy 2008;9(13):2383-90.
2008: Alasdair J Gray; Steven Goodacre; David E Newby; Moyra Masson; Fiona Sampson; Jon P Nicholl
Noninvasive ventilation in acute cardiogenic pulmonary edema.
The New England journal of medicine 2008;359(2):142-51.
2008: Ninian N Lang; Ingibjörg J Gudmundsdóttir; Nicholas A Boon; Christopher A Ludlam; Keith A Fox; David E Newby
Marked impairment of protease-activated receptor type 1-mediated vasodilation and fibrinolysis in cigarette smokers: smoking, thrombin, and vascular responses in vivo.
Journal of the American College of Cardiology 2008;52(1):33-9.
2008: M D Cross; Nicholas L Mills; M Al-Abri; R Riha; Marjorie Vennelle; Thomas W Mackay; David E Newby; Neil J Douglas
Continuous positive airway pressure improves vascular function in obstructive sleep apnoea/hypopnoea syndrome: a randomised controlled trial.
Thorax 2008;63(7):578-83.
2008: Nicholas L Mills; Simon D Robinson; Paul H B Fokkens; Daan L A C Leseman; Mark R Miller; David Anderson; Evelyn J Freney; Mathew R Heal; Robert J Donovan; Anders Blomberg; Thomas Sandström; William MacNee; Nicholas A Boon; Ken Donaldson; David E Newby; Flemming R Cassee
Exposure to concentrated ambient particles does not affect vascular function in patients with coronary heart disease.
Environmental health perspectives 2008;116(6):709-15.
2008: Alan G Japp; David E Newby
The apelin-APJ system in heart failure: pathophysiologic relevance and therapeutic potential.
Biochemical pharmacology 2008;75(10):1882-92.
2008: Ingibjörg J Gudmundsdóttir; Ninian N Lang; Nicholas A Boon; Christopher A Ludlam; David J Webb; Keith A A Fox; David E Newby
Role of the endothelium in the vascular effects of the thrombin receptor (protease-activated receptor type 1) in humans.
Journal of the American College of Cardiology 2008;51(18):1749-56.
2008: Nicholas L Mills; J J Miller; A Anand; Simon D Robinson; G A Frazer; D Anderson; L Breen; I B Wilkinson; C M McEniery; Ken Donaldson; David E Newby; William MacNee
Increased arterial stiffness in patients with chronic obstructive pulmonary disease: a mechanism for increased cardiovascular risk.
Thorax 2008;63(4):306-11.
2008: Jehangir N Din; Scott A Harding; Christopher J Valerio; Jaydeep Sarma; Karin Lyall; Rudolph A Riemersma; David E Newby; Andrew D Flapan
Dietary intervention with oil rich fish reduces platelet-monocyte aggregation in man.
Atherosclerosis 2008;197(1):290-6.
2008: Nicholas L M Cruden; Scott A Harding; David E Newby
Coronary stent thrombosis in the perioperative period.
BMJ (Clinical research ed.) 2008;337():a2074.
2007: David A McAllister; John D Maclay; Nicholas L Mills; Grant Mair; Joy Miller; David Anderson; David E Newby; John Murchison; William MacNee
Arterial stiffness is independently associated with emphysema severity in patients with chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine 2007;176(12):1208-14.
2007: Lindsay A Smith; Dennis W S Chong; Marjorie Vennelle; Martin A Denvir; David E Newby; Neil J Douglas
Diagnosis of sleep-disordered breathing in patients with chronic heart failure: evaluation of a portable limited sleep study system.
Journal of sleep research 2007;16(4):428-35.
2007: Nicholas L M Cruden; Chun H Teh; Ian R Starkey; David E Newby
Reduced vascular complications and length of stay with transradial rescue angioplasty for acute myocardial infarction.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2007;70(5):670-5.
2007: Nicholas L Mills; Håkan Törnqvist; Manuel C Gonzalez; Elen Vink; Simon D Robinson; Stefan Söderberg; Nicholas A Boon; Ken Donaldson; Thomas Sandström; Anders Blomberg; David E Newby
Ischemic and thrombotic effects of dilute diesel-exhaust inhalation in men with coronary heart disease.
The New England journal of medicine 2007;357(11):1075-82.
2007: Anna R Dover; Patrick W F Hadoke; Brian R Walker; David E Newby
Acute effects of glucocorticoids on endothelial fibrinolytic and vasodilator function in humans.
Journal of cardiovascular pharmacology 2007;50(3):321-6.
2007: Håkan Törnqvist; Nicholas L Mills; Manuel Gonzalez; Mark R Miller; Simon D Robinson; Ian L Megson; William MacNee; Ken Donaldson; Stefan Söderberg; David E Newby; Thomas Sandström; Anders Blomberg
Persistent endothelial dysfunction in humans after diesel exhaust inhalation.
American journal of respiratory and critical care medicine 2007;176(4):395-400.
2007: Scott A Harding; Jehangir N Din; Jaydeep Sarma; Alasdair Jessop; Mark Weatherall; Keith A A Fox; David E Newby
Flow cytometric analysis of circulating platelet-monocyte aggregates in whole blood: methodological considerations.
Thrombosis and haemostasis 2007;98(2):451-6.
2007: Simon D Robinson; Christopher A Ludlam; Nicholas A Boon; David E Newby
Endothelial fibrinolytic capacity predicts future adverse cardiovascular events in patients with coronary heart disease.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(7):1651-6.
2007: Lindsay A Smith; Marjorie Vennelle; Roy S Gardner; Theresa A McDonagh; Martin A Denvir; Neil J Douglas; David E Newby
Auto-titrating continuous positive airway pressure therapy in patients with chronic heart failure and obstructive sleep apnoea: a randomized placebo-controlled trial.
European heart journal 2007;28(10):1221-7.
2007: Andrew J Lucking; David E Newby
Pharmacological antithrombotic adjuncts to percutaneous coronary intervention.
Expert opinion on pharmacotherapy 2007;8(6):759-76.
2007: Ninian N Lang; Leonid Luksha; David E Newby; Karolina Kublickiene
Connexin 43 mediates endothelium-derived hyperpolarizing factor-induced vasodilatation in subcutaneous resistance arteries from healthy pregnant women.
American journal of physiology. Heart and circulatory physiology 2007;292(2):H1026-32.
2007: Nicholas L Mills; Håkan Törnqvist; Simon D Robinson; Manuel C Gonzalez; Stefan Söderberg; Thomas Sandström; Anders Blomberg; David E Newby; Ken Donaldson
Air pollution and atherothrombosis.
Inhalation toxicology 2007;19 Suppl 1():81-9.
2007: Emma S Houslay; Tristan Lawton; Anshuman Sengupta; Neal G Uren; Graham McKillop; David E Newby
Non-invasive assessment of coronary artery bypass graft patency using 16-slice computed tomography angiography.
Journal of cardiothoracic surgery 2007;2():27.
2007: Amy O Robb; Nicholas L Mills; David E Newby; Fiona C Denison
Endothelial progenitor cells in pregnancy.
Reproduction (Cambridge, England) 2007;133(1):1-9.
2007: Anna R Dover; Patrick W F Hadoke; Linsay J Macdonald; Eileen Miller; David E Newby; Brian R Walker
Intravascular glucocorticoid metabolism during inflammation and injury in mice.
Endocrinology 2007;148(1):166-72.
2006: Scott A Harding; Jehangir N Din; Jaydeep Sarma; D H Josephs; Keith A A Fox; David E Newby
Promotion of proinflammatory interactions between platelets and monocytes by unfractionated heparin.
Heart (British Cardiac Society) 2006;92(11):1635-8.
2006: Ingibjörg J Gudmundsdóttir; Ian L Megson; Jillian S Kell; Christopher A Ludlam; Keith A A Fox; David J Webb; David E Newby
Direct vascular effects of protease-activated receptor type 1 agonism in vivo in humans.
Circulation 2006;114(15):1625-32.
2006: Simon D Robinson; Christopher A Ludlam; Nicholas A Boon; David E Newby
Tissue plasminogen activator genetic polymorphisms do not influence tissue plasminogen activator release in patients with coronary heart disease.
Journal of thrombosis and haemostasis : JTH 2006;4(10):2262-9.
2006: Anna R Dover; Stanley Chia; James W Ferguson; Nicholas L M Cruden; Ian L Megson; Keith A A Fox; David E Newby
Inducible nitric oxide synthase activity does not contribute to the maintenance of peripheral vascular tone in patients with heart failure.
Clinical science (London, England : 1979) 2006;111(4):275-80.
2006: Scott A Harding; Jaydeep Sarma; Jehangir N Din; P M Maciocia; David E Newby; Keith A A Fox
Clopidogrel reduces platelet-leucocyte aggregation, monocyte activation and RANTES secretion in type 2 diabetes mellitus.
Heart (British Cardiac Society) 2006;92(9):1335-7.
2006: E S Houslay; S Joanna Cowell; Robin J Prescott; John Reid; J Burton; David B Northridge; Nicholas A Boon; David E Newby
Progressive coronary calcification despite intensive lipid-lowering treatment: a randomised controlled trial.
Heart (British Cardiac Society) 2006;92(9):1207-12.
2006: David E Newby
Can intensive statin therapy cause regression of coronary atherosclerosis?
Nature clinical practice. Cardiovascular medicine 2006;3(7):354-5.
2006: Emer Henry; David E Newby; David J Webb; Patrick W F Hadoke; Colm J O'Brien
Altered endothelin-1 vasoreactivity in patients with untreated normal-pressure glaucoma.
Investigative ophthalmology & visual science 2006;47(6):2528-32.
2006: David E Newby; S Joanna Cowell; Nicholas A Boon
Emerging medical treatments for aortic stenosis: statins, angiotensin converting enzyme inhibitors, or both?
Heart (British Cardiac Society) 2006;92(6):729-34.
2006: Simon D Robinson; Scott A Harding; P Cummins; Jehangir N Din; Jaydeep Sarma; I Davidson; Keith A A Fox; Nicholas A Boon; David E Newby
Functional interplay between platelet activation and endothelial dysfunction in patients with coronary heart disease.
Platelets 2006;17(3):158-62.
2006: Ahmed Helmy; James W Ferguson; Peter C Hayes; David E Newby; David J Webb
Bradykinin does not contribute to peripheral vascular tone in patients with cirrhosis and ascites.
Journal of cardiovascular pharmacology 2006;47(4):556-60.
2006: James W Ferguson; Anna R Dover; Stanley Chia; Nicholas L M Cruden; Peter C Hayes; David E Newby
Inducible nitric oxide synthase activity contributes to the regulation of peripheral vascular tone in patients with cirrhosis and ascites.
Gut 2006;55(4):542-6.
2006: Carmel M Moran; James A Ross; C Cunningham; M Butler; Tom Anderson; David E Newby; Keith A A Fox; W Norman McDicken
Manufacture and acoustical characterisation of a high-frequency contrast agent for targeting applications.
Ultrasound in medicine & biology 2006;32(3):421-8.
2006: Simon D Robinson; Pamela Dawson; Christopher A Ludlam; Nicholas A Boon; David E Newby
Vascular and fibrinolytic effects of intra-arterial tumour necrosis factor-alpha in patients with coronary heart disease.
Clinical science (London, England : 1979) 2006;110(3):353-60.
2006: Nicholas L Mills; Nadia Amin; Simon D Robinson; Atul Anand; John Davies; Dilip Patel; Jesus M de la Fuente; Flemming R Cassee; Nicholas A Boon; William MacNee; Alistair M Millar; Ken Donaldson; David E Newby
Do inhaled carbon nanoparticles translocate directly into the circulation in humans?
American journal of respiratory and critical care medicine 2006;173(4):426-31.
2006: Simon D Robinson; Christopher A Ludlam; Nicholas A Boon; David E Newby
Phosphodiesterase type 5 inhibition does not reverse endothelial dysfunction in patients with coronary heart disease.
Heart (British Cardiac Society) 2006;92(2):170-6.
2006: Evelyn J Freney; Mathew R Heal; Robert J Donovan; Nicholas L Mills; Ken Donaldson; David E Newby; Paul H B Fokkens; Flemming R Cassee
A single-particle characterization of a mobile Versatile Aerosol Concentration Enrichment System for exposure studies.
Particle and fibre toxicology 2006;3():8.
2006: Nicholas L M Cruden; Catriona Graham; Scott A Harding; Christopher A Ludlam; Keith A A Fox; David E Newby
Plasma TAFI and soluble CD40 ligand do not predict reperfusion following thrombolysis for acute myocardial infarction.
Thrombosis research 2006;118(2):189-97.
2005: Saibal K Biswas; David E Newby; Irfan Rahman; Ian L Megson
Depressed glutathione synthesis precedes oxidative stress and atherogenesis in Apo-E(-/-) mice.
Biochemical and biophysical research communications 2005;338(3):1368-73.
2005: Nicholas L Mills; Håkan Törnqvist; Simon D Robinson; Manuel Gonzalez; Kareen Darnley; William MacNee; Nicholas A Boon; Ken Donaldson; Anders Blomberg; Thomas Sandstrom; David E Newby
Diesel exhaust inhalation causes vascular dysfunction and impaired endogenous fibrinolysis.
Circulation 2005;112(25):3930-6.
2005: Neeraj Dhaun; Fiona E Strachan; David E Newby; Neil R Johnston; Neville F Ford; Janis L Hammett; Maria Palmisano; David J Webb
Vasodilator effects of the endothelin ET receptor selective antagonist BMS-193884 in healthy men.
British journal of clinical pharmacology 2005;60(6):611-22.
2005: James J Oliver; David J Webb; David E Newby
Stimulated tissue plasminogen activator release as a marker of endothelial function in humans.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(12):2470-9.
2005: Nicholas L M Cruden; David E Newby
Clots, kinins and coronaries.
Atherosclerosis 2005;183(2):189-98.
2005: Ingibjörg J Gudmundsdóttir; Sarah J McRobbie; Simon D Robinson; David E Newby; Ian L Megson
Sildenafil potentiates nitric oxide mediated inhibition of human platelet aggregation.
Biochemical and biophysical research communications 2005;337(1):382-5.
2005: Ken Donaldson; Lang Tran; Luis A Jimenez; Rodger Duffin; David E Newby; Nicholas L Mills; William MacNee; Vicki Stone
Combustion-derived nanoparticles: a review of their toxicology following inhalation exposure.
Particle and fibre toxicology 2005;2():10.
2005: Nicholas L M Cruden; L Lawes; P Masson; Simon D Robinson; Christopher A Ludlam; David E Newby
Inhibition of thrombin activatable fibrinolysis inhibitor augments fibrinolysis in human whole blood.
Journal of thrombosis and haemostasis : JTH 2005;3(10):2351-3.
2005: Stephen J Leslie; J C S Spratt; Sinéad P McKee; Fiona E Strachan; David E Newby; David B Northridge; Martin A Denvir; David J Webb
Direct comparison of selective endothelin A and non-selective endothelin A/B receptor blockade in chronic heart failure.
Heart (British Cardiac Society) 2005;91(7):914-9.
2005: S Joanna Cowell; David E Newby; Robin J Prescott; Peter Bloomfield; John Reid; David B Northridge; Nicholas A Boon
A randomized trial of intensive lipid-lowering therapy in calcific aortic stenosis.
The New England journal of medicine 2005;352(23):2389-97.
2005: T Attinà; R Camidge; David E Newby; David J Webb
Endothelin antagonism in pulmonary hypertension, heart failure, and beyond.
Heart (British Cardiac Society) 2005;91(6):825-31.
2005: Nicholas L M Cruden; George H Tse; Keith A A Fox; Christopher A Ludlam; Ian L Megson; David E Newby
B1 kinin receptor does not contribute to vascular tone or tissue plasminogen activator release in the peripheral circulation of patients with heart failure.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(4):772-7.
2005: Lynn D Greig; Stephen J Leslie; Fraser W Gibb; Sherilyn Tan; David E Newby; David J Webb
Comparative effects of glyceryl trinitrate and amyl nitrite on pulse wave reflection and augmentation index.
British journal of clinical pharmacology 2005;59(3):265-70.
2005: Stanley Chia; Robert Wilson; Christopher A Ludlam; David J Webb; Andrew D Flapan; David E Newby
Endothelial dysfunction in patients with recent myocardial infarction and hyperhomocysteinaemia: effects of vitamin supplementation.
Clinical science (London, England : 1979) 2005;108(1):65-72.
2004: Nicholas L M Cruden; Keith A A Fox; Christopher A Ludlam; Neil R Johnston; David E Newby
Neutral endopeptidase inhibition augments vascular actions of bradykinin in patients treated with angiotensin-converting enzyme inhibition.
Hypertension 2004;44(6):913-8.
2004: Stephen J Leslie; Neil Johnston; Fiona E Strachan; Alan Bagnall; Gillian A Gray; David E Newby; Martin A Denvir; David J Webb
Endothelin-1[1-31] is not elevated in men with chronic heart failure.
Journal of cardiovascular pharmacology 2004;44 Suppl 1():S96-9.
2004: S Joanna Cowell; David E Newby; Nicholas A Boon; Andrew T Elder
Calcific aortic stenosis: same old story?
Age and ageing 2004;33(6):538-44.
2004: Stephen J Leslie; Sinéad McKee; David E Newby; David J Webb; Martin A Denvir
Non-invasive measurement of cardiac output in patients with chronic heart failure.
Blood pressure monitoring 2004;9(5):277-80.
2004: Scott A Harding; Andrew J Sommerfield; Jaydeep Sarma; P J Twomey; David E Newby; Brian M Frier; Keith A A Fox
Increased CD40 ligand and platelet-monocyte aggregates in patients with type 1 diabetes mellitus.
Atherosclerosis 2004;176(2):321-5.
2004: Maria Paola Pellegrini; David E Newby; Neil R Johnston; Simon Maxwell; David J Webb
Vitamin C has no effect on endothelium-dependent vasomotion and acute endogenous fibrinolysis in healthy smokers.
Journal of cardiovascular pharmacology 2004;44(1):117-24.
2004: Stephen J Leslie; Mamun Q Rahman; Martin A Denvir; David E Newby; David J Webb
Endothelins and their inhibition in the human skin microcirculation: ET[1-31], a new vasoconstrictor peptide.
British journal of clinical pharmacology 2004;57(6):720-5.
2004: Nicholas L M Cruden; Fraser N Witherow; David J Webb; Keith A A Fox; David E Newby
Bradykinin contributes to the systemic hemodynamic effects of chronic angiotensin-converting enzyme inhibition in patients with heart failure.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(6):1043-8.
2004: Scott A Harding; Jaydeep Sarma; D H Josephs; Nicholas L M Cruden; Jehangir N Din; P J Twomey; Keith A A Fox; David E Newby
Upregulation of the CD40/CD40 ligand dyad and platelet-monocyte aggregation in cigarette smokers.
Circulation 2004;109(16):1926-9.
2004: Lindsay A Smith; S Joanna Cowell; Audrey C White; Nicholas A Boon; David E Newby; David B Northridge
Contrast agent increases Doppler velocities and improves reproducibility of aortic valve area measurements in patients with aortic stenosis.
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2004;17(3):247-52.
2004: Andrew L McLeod; Neal G Uren; Ian B Wilkinson; David J Webb; Simon R J Maxwell; David B Northridge; David E Newby
Non-invasive measures of pulse wave velocity correlate with coronary arterial plaque load in humans.
Journal of hypertension 2004;22(2):363-8.
2004: Andrew L McLeod; Robin J Watson; Thomas Anderson; Scott Inglis; David E Newby; David B Northridge; Neal G Uren; W Norman McDicken
Classification of arterial plaque by spectral analysis in remodelled human atherosclerotic coronary arteries.
Ultrasound in medicine & biology 2004;30(2):155-9.
2004: Jehangir N Din; David E Newby; Andrew D Flapan
Omega 3 fatty acids and cardiovascular disease--fishing for a natural treatment.
BMJ (Clinical research ed.) 2004;328(7430):30-5.
2004: Nicholas L M Cruden; David E Newby
Angiotensin antagonism in patients with heart failure: ACE inhibitors, angiotensin receptor antagonists or both?
American journal of cardiovascular drugs : drugs, devices, and other interventions 2004;4(6):345-53.
2003: S Joanna Cowell; David E Newby; J Burton; A White; David B Northridge; Nicholas A Boon; John Reid
Aortic valve calcification on computed tomography predicts the severity of aortic stenosis.
Clinical radiology 2003;58(9):712-6.
2003: Fraser N Witherow; Pamela Dawson; Christopher A Ludlam; David J Webb; Keith A A Fox; David E Newby
Bradykinin receptor antagonism and endothelial tissue plasminogen activator release in humans.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(9):1667-70.
2003: Andrew L McLeod; David E Newby; David B Northridge; Keith A A Fox; Neal G Uren
Influence of differential vascular remodeling on the coronary vasomotor response.
Cardiovascular research 2003;59(2):520-6.
2003: Jonathan T Affolter; Sinéad P McKee; Ahmed Helmy; Richard jones; David E Newby; David J Webb
Intra-arterial vasopressin in the human forearm: pharmacodynamics and the role of nitric oxide.
Clinical pharmacology and therapeutics 2003;74(1):9-16.
2003: Stanley Chia; Motaz Qadan; Richard Newton; Christopher A Ludlam; Keith A A Fox; David E Newby
Intra-arterial tumor necrosis factor-alpha impairs endothelium-dependent vasodilatation and stimulates local tissue plasminogen activator release in humans.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(4):695-701.
2003: Mark R Miller; Inderraj S Hanspal; Patrick W F Hadoke; David E Newby; Adriano G Rossi; David J Webb; Ian L Megson
A novel S-nitrosothiol causes prolonged and selective inhibition of platelet adhesion at sites of vascular injury.
Cardiovascular research 2003;57(3):853-60.
2003: Stanley Chia; Christopher A Ludlam; Keith A A Fox; David E Newby
Acute systemic inflammation enhances endothelium-dependent tissue plasminogen activator release in men.
Journal of the American College of Cardiology 2003;41(2):333-9.
2003: Stanley Chia; Ian L Megson; Christopher A Ludlam; Keith A A Fox; David E Newby
Preserved endothelial vasomotion and fibrinolytic function in patients with acute stent thrombosis or in-stent restenosis.
Thrombosis research 2003;111(6):343-9.
2003: Loukianos Gatzoulis; Kumar V Ramnarine; Stephen D Pye; Tom Anderson; David E Newby; Peter R Hoskins; W Norman McDicken
Doppler colour flow imaging and flow quantification with a novel forward-viewing intravascular ultrasound system.
Ultrasound in medicine & biology 2003;29(1):53-64.
2003: Peter A Henriksen; David E Newby
Therapeutic inhibition of tumour necrosis factor alpha in patients with heart failure: cooling an inflamed heart.
Heart (British Cardiac Society) 2003;89(1):14-8.
2002: Jonathan T Affolter; David E Newby; Ian B Wilkinson; matthew winter; Richard J Balment; David J Webb
No effect on central or peripheral blood pressure of systemic urotensin II infusion in humans.
British journal of clinical pharmacology 2002;54(6):617-21.
2002: David E Newby; Peter C Hayes
Hyperdynamic circulation in liver cirrhosis: not peripheral vasodilatation but 'splanchnic steal'.
QJM : monthly journal of the Association of Physicians 2002;95(12):827-30.
2002: Nicholas L M Cruden; David E Newby; David J Webb
Salmeterol for the prevention of high-altitude pulmonary edema.
The New England journal of medicine 2002;347(16):1282-5; author reply 1282-5.
2002: Fraser N Witherow; Pamela Dawson; Christopher A Ludlam; Keith A A Fox; David E Newby
Marked bradykinin-induced tissue plasminogen activator release in patients with heart failure maintained on long-term angiotensin-converting enzyme inhibitor therapy.
Journal of the American College of Cardiology 2002;40(5):961-6.
2002: David E Newby; Fiona E Strachan; David J Webb
Abnormal endothelin B receptor vasomotor responses in patients with Hirschsprung's disease.
QJM : monthly journal of the Association of Physicians 2002;95(3):159-63.
2002: Stanley Chia; David E Newby
Atherosclerosis, cigarette smoking, and endogenous fibrinolysis: is there a direct link?
Current atherosclerosis reports 2002;4(2):143-8.
2002: David E Newby; Fraser N Witherow; R A Wright; Peter Bloomfield; Christopher A Ludlam; Nicholas A Boon; Keith A A Fox; David J Webb
Hypercholesterolaemia and lipid lowering treatment do not affect the acute endogenous fibrinolytic capacity in vivo.
Heart (British Cardiac Society) 2002;87(1):48-53.
2001: C Labinjoh; David E Newby; Maria Paola Pellegrini; Neil R Johnston; Nicholas A Boon; David J Webb
Potentiation of bradykinin-induced tissue plasminogen activator release by angiotensin-converting enzyme inhibition.
Journal of the American College of Cardiology 2001;38(5):1402-8.
2001: Maria Paola Pellegrini; David E Newby; S Maxwell; David J Webb
Short-term effects of transdermal nicotine on acute tissue plasminogen activator release in vivo in man.
Cardiovascular research 2001;52(2):321-7.
2001: Fraser N Witherow; Ahmed Helmy; David J Webb; Keith A A Fox; David E Newby
Bradykinin contributes to the vasodilator effects of chronic angiotensin-converting enzyme inhibition in patients with heart failure.
Circulation 2001;104(18):2177-81.
2001: David E Newby; Andrew L McLeod; Neal G Uren; L Flint; Christopher A Ludlam; David J Webb; Keith A A Fox; Nicholas A Boon
Impaired coronary tissue plasminogen activator release is associated with coronary atherosclerosis and cigarette smoking: direct link between endothelial dysfunction and atherothrombosis.
Circulation 2001;103(15):1936-41.
2001: C Labinjoh; David E Newby; Ian B Wilkinson; Ian L Megson; Helen MacCallum; V Melville; Nicholas A Boon; David J Webb
Effects of acute methionine loading and vitamin C on endogenous fibrinolysis, endothelium-dependent vasomotion and platelet aggregation.
Clinical science (London, England : 1979) 2001;100(2):127-35.
2001: M C Chui; David E Newby; M Panarelli; Peter Bloomfield; Nicholas A Boon
Association between calcific aortic stenosis and hypercholesterolemia: is there a need for a randomized controlled trial of cholesterol-lowering therapy?
Clinical cardiology 2001;24(1):52-5.
2000: C Labinjoh; David E Newby; Pamela Dawson; Neil R Johnston; Christopher A Ludlam; Nicholas A Boon; David J Webb
Fibrinolytic actions of intra-arterial angiotensin II and bradykinin in vivo in man.
Cardiovascular research 2000;47(4):707-14.
2000: David E Newby; A Stewart; Fraser N Witherow; S Grieve; Pamela Dawson; Keith A A Fox; David J Webb; Christopher A Ludlam
Local and systemic effects of intra-arterial desmopressin in healthy volunteers and patients with type 3 von Willebrand disease. Role of interleukin-6.
Thrombosis and haemostasis 2000;84(2):195-203.
2000: N Sogo; Ian B Wilkinson; Helen MacCallum; S Q Khan; Fiona E Strachan; David E Newby; Ian L Megson; David J Webb
A novel S-nitrosothiol (RIG200) causes prolonged relaxation in dorsal hand veins with damaged endothelium.
Clinical pharmacology and therapeutics 2000;68(1):75-81.
2000: Ian B Wilkinson; Helen MacCallum; L Flint; John R Cockcroft; David E Newby; David J Webb
The influence of heart rate on augmentation index and central arterial pressure in humans.
The Journal of physiology 2000;525 Pt 1():263-70.
1999: David B Northridge; David E Newby; Esther Rooney; J Norrie; Henry J Dargie
Comparison of the short-term effects of candoxatril, an orally active neutral endopeptidase inhibitor, and frusemide in the treatment of patients with chronic heart failure.
American heart journal 1999;138(6 Pt 1):1149-57.
1999: David E Newby; Nicholas A Boon
Lower cardiac mortality in smokers following thrombolysis.
QJM : monthly journal of the Association of Physicians 1999;92(11):679-81.
1999: Nicholas L M Cruden; David E Newby; J A Ross; Neil R Johnston; David J Webb
Effect of cold exposure, exercise and high altitude on plasma endothelin-1 and endothelial cell markers in man.
Scottish medical journal 1999;44(5):143-6.
1999: David E Newby; David G Sciberras; C J Ferro; Barry J Gertz; D Sommerville; A Majumdar; R C Lowry; David J Webb
Substance P-induced vasodilatation is mediated by the neurokinin type 1 receptor but does not contribute to basal vascular tone in man.
British journal of clinical pharmacology 1999;48(3):336-44.
1999: NE Goodfield; David E Newby; Christopher A Ludlam; Andrew D Flapan
Effects of acute angiotensin II type 1 receptor antagonism and angiotensin converting enzyme inhibition on plasma fibrinolytic parameters in patients with heart failure.
Circulation 1999;99(23):2983-5.
1999: David E Newby; R A Wright; C Labinjoh; Christopher A Ludlam; Keith A A Fox; Nicholas A Boon; David J Webb
Endothelial dysfunction, impaired endogenous fibrinolysis, and cigarette smoking: a mechanism for arterial thrombosis and myocardial infarction.
Circulation 1999;99(11):1411-5.
1999: David B Northridge; P F Currie; David E Newby; john mcmurray; M Ford; Nicholas A Boon; Henry J Dargie
Placebo-controlled comparison of candoxatril, an orally active neutral endopeptidase inhibitor, and captopril in patients with chronic heart failure.
European journal of heart failure 1999;1(1):67-72.
1998: David E Newby; T McDonagh; P F Currie; David B Northridge; Nicholas A Boon; Henry J Dargie
Candoxatril improves exercise capacity in patients with chronic heart failure receiving angiotensin converting enzyme inhibition.
European heart journal 1998;19(12):1808-13.
1998: David E Newby; NE Goodfield; Andrew D Flapan; Nicholas A Boon; K A Fox; David J Webb
Regulation of peripheral vascular tone in patients with heart failure: contribution of angiotensin II.
Heart (British Cardiac Society) 1998;80(2):134-40.
1998: David E Newby; L L Flint; O El Hag
Heart rate increases in tilt test.
Circulation 1998;98(2):187-8.
1998: David E Newby; L L Flint; Keith A A Fox; Nicholas A Boon; David J Webb
Reduced responsiveness to endothelin-1 in peripheral resistance vessels of patients with syndrome X.
Journal of the American College of Cardiology 1998;31(7):1585-90.
1998: David E Newby; K A Fox; L L Flint; Nicholas A Boon
A 'same day' direct-access chest pain clinic: improved management and reduced hospitalization.
QJM : monthly journal of the Association of Physicians 1998;91(5):333-7.
1998: David E Newby; R A Wright; Pamela Dawson; Christopher A Ludlam; Nicholas A Boon; Keith A A Fox; David J Webb
The L-arginine/nitric oxide pathway contributes to the acute release of tissue plasminogen activator in vivo in man.
Cardiovascular research 1998;38(2):485-92.
1998: David E Newby; R Jalan; S Masumori; P C Hayes; Nicholas A Boon; David J Webb
Peripheral vascular tone in patients with cirrhosis: role of the renin-angiotensin and sympathetic nervous systems.
Cardiovascular research 1998;38(1):221-8.
1997: David E Newby; S Masumori; Neil R Johnston; Nicholas A Boon; David J Webb
Endogenous angiotensin II contributes to basal peripheral vascular tone in sodium deplete but not sodium replete man.
Cardiovascular research 1997;36(2):268-75.
1997: David E Newby; R A Wright; Christopher A Ludlam; Keith A A Fox; Nicholas A Boon; David J Webb
An in vivo model for the assessment of acute fibrinolytic capacity of the endothelium.
Thrombosis and haemostasis 1997;78(4):1242-8.
1997: C J Ferro; W G Haynes; Neil R Johnston; C C Lomax; David E Newby; David J Webb
The peptide endothelin receptor antagonist, TAK-044, produces sustained inhibition of endothelin-1 mediated arteriolar vasoconstriction.
British journal of clinical pharmacology 1997;44(4):377-83.
1997: S Masumori; David E Newby; F E Strachan; Nicholas A Boon; David J Webb
Endogenous angiotensin II does not contribute to sympathetic venoconstriction in dorsal hand veins of healthy humans.
Clinical pharmacology and therapeutics 1997;62(3):327-33.
1997: David E Newby; David G Sciberras; C M Mendel; Barry J Gertz; Nicholas A Boon; David J Webb
Intra-arterial substance P mediated vasodilatation in the human forearm: pharmacology, reproducibility and tolerability.
British journal of clinical pharmacology 1997;43(5):493-9.
1997: David E Newby; Nicholas A Boon; D J Webb
Comparison of forearm vasodilatation to substance P and acetylcholine: contribution of nitric oxide.
Clinical science (London, England : 1979) 1997;92(2):133-8.
1996: David E Newby; D J Webb
Advances in clinical pharmacology and therapeutics: endothelin.
British journal of hospital medicine 1996;56(7):360-4.
1996: David E Newby; James M M Neilson; D R Jarvie; Nicholas A Boon
Caffeine restriction has no role in the management of patients with symptomatic idiopathic ventricular premature beats.
Heart (British Cardiac Society) 1996;76(4):355-7.
1995: David E Newby; M R Lee; Alasdair J Gray; Nicholas A Boon
Enalapril overdose and the corrective effect of intravenous angiotensin II.
British journal of clinical pharmacology 1995;40(1):103-4.