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William Newcomb
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Anatomy
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Network (preview)
46
Brown, Jay
19
Steven, Alasdair
19
Trus, Benes
18
Homa, Fred
14
booy, frank
13
Thomsen, Darrell
9
Cheng, Naiqian
5
Weller, Sandra
4
Baker, Timothy
3
Conway, James
3
Gao, Min
3
Tenney, Daniel
3
Sheaffer, AK
2
Olson, Norman
2
Spencer, JV
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Publications
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Geonetwork of William Newcomb (preview)
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All Publications
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2009: Newcomb William W; Cockrell Shelley K; Homa Fred L; Brown Jay C
Polarized DNA ejection from the herpesvirus capsid.
Journal of molecular biology 2009;392(4):885-94.
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2009: Newcomb William W; Brown Jay C
Time-dependent transformation of the herpesvirus tegument.
Journal of virology 2009;83(16):8082-9.
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2009: Copeland Anna Maria; Newcomb William W; Brown Jay C
Herpes simplex virus replication: roles of viral proteins and nucleoporins in capsid-nucleus attachment.
Journal of virology 2009;83(4):1660-8.
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2007: Newcomb William W; Booy Frank P; Brown Jay C
Uncoating the herpes simplex virus genome.
Journal of molecular biology 2007;370(4):633-42.
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2007: Spano Anthony J; Chen Frank S; Goodman Benjamin E; Sabat Agnes E; Simon Martha N; Wall Joseph S; Correia John J; McIvor Wilson; Newcomb William W; Brown Jay C; Schnur Joel M; Lebedev Nikolai
In vitro assembly of a prohead-like structure of the Rhodobacter capsulatus gene transfer agent.
Virology 2007;364(1):95-102.
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2007: Trus Benes L; Newcomb William W; Cheng Naiqian; Cardone Giovanni; Marekov Lyuben; Homa Fred L; Brown Jay C; Steven Alasdair C
Allosteric signaling and a nuclear exit strategy: binding of UL25/UL17 heterodimers to DNA-Filled HSV-1 capsids.
Molecular cell 2007;26(4):479-89.
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2007: Cardone Giovanni; Winkler Dennis C; Trus Benes L; Cheng Naiqian; Heuser John E; Newcomb William W; Brown Jay C; Steven Alasdair C
Visualization of the herpes simplex virus portal in situ by cryo-electron tomography.
Virology 2007;361(2):426-34.
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2006: Newcomb William W; Homa Fred L; Brown Jay C
Herpes simplex virus capsid structure: DNA packaging protein UL25 is located on the external surface of the capsid near the vertices.
Journal of virology 2006;80(13):6286-94.
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2005: Newcomb William W; Homa Fred L; Brown Jay C
Involvement of the portal at an early step in herpes simplex virus capsid assembly.
Journal of virology 2005;79(16):10540-6.
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2005: Singer Gregory P; Newcomb William W; Thomsen Darrel R; Homa Fred L; Brown Jay C
Identification of a region in the herpes simplex virus scaffolding protein required for interaction with the portal.
Journal of virology 2005;79(1):132-9.
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2004: Trus Benes L; Cheng Naiqian; Newcomb William W; Homa Fred L; Brown Jay C; Steven Alasdair C
Structure and polymorphism of the UL6 portal protein of herpes simplex virus type 1.
Journal of virology 2004;78(22):12668-71.
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2003: Newcomb William W; Thomsen Darrell R; Homa Fred L; Brown Jay C
Assembly of the herpes simplex virus capsid: identification of soluble scaffold-portal complexes and their role in formation of portal-containing capsids.
Journal of virology 2003;77(18):9862-71.
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2003: Heymann J Bernard; Cheng Naiqian; Newcomb William W; Trus Benes L; Brown Jay C; Steven Alasdair C
Dynamics of herpes simplex virus capsid maturation visualized by time-lapse cryo-electron microscopy.
Nature structural biology 2003;10(5):334-41.
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2002: Newcomb William W; Brown Jay C
Inhibition of herpes simplex virus replication by WAY-150138: assembly of capsids depleted of the portal and terminase proteins involved in DNA encapsidation.
Journal of virology 2002;76(19):10084-8.
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2002: Cheng Naiqian; Trus Benes L; Belnap David M; Newcomb William W; Brown Jay C; Steven Alasdair C
Handedness of the herpes simplex virus capsid and procapsid.
Journal of virology 2002;76(15):7855-9.
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2002: Gruenke Jennifer A; Armstrong R Todd; Newcomb William W; Brown Jay C; White Judith M
New insights into the spring-loaded conformational change of influenza virus hemagglutinin.
Journal of virology 2002;76(9):4456-66.
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2001: Newcomb W W; Juhas R M; Thomsen D R; Homa F L; Burch A D; Weller S K; Brown J C
The UL6 gene product forms the portal for entry of DNA into the herpes simplex virus capsid.
Journal of virology 2001;75(22):10923-32.
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2001: Trus B L; Heymann J B; Nealon K; Cheng N; Newcomb W W; Brown J C; Kedes D H; Steven A C
Capsid structure of Kaposi's sarcoma-associated herpesvirus, a gammaherpesvirus, compared to those of an alphaherpesvirus, herpes simplex virus type 1, and a betaherpesvirus, cytomegalovirus.
Journal of virology 2001;75(6):2879-90.
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2001: Nealon K; Newcomb W W; Pray T R; Craik C S; Brown J C; Kedes D H
Lytic replication of Kaposi's sarcoma-associated herpesvirus results in the formation of multiple capsid species: isolation and molecular characterization of A, B, and C capsids from a gammaherpesvirus.
Journal of virology 2001;75(6):2866-78.
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2001: Newcomb W W; Homa F L; Thomsen D R; Brown J C
In vitro assembly of the herpes simplex virus procapsid: formation of small procapsids at reduced scaffolding protein concentration.
Journal of structural biology 2001;133(1):23-31.
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2001: Sheaffer A K; Newcomb W W; Gao M; Yu D; Weller S K; Brown J C; Tenney D J
Herpes simplex virus DNA cleavage and packaging proteins associate with the procapsid prior to its maturation.
Journal of virology 2001;75(2):687-98.
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2000: Sheaffer A K; Newcomb W W; Brown J C; Gao M; Weller S K; Tenney D J
Evidence for controlled incorporation of herpes simplex virus type 1 UL26 protease into capsids.
Journal of virology 2000;74(15):6838-48.
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2000: Newcomb W W; Trus B L; Cheng N; Steven A C; Sheaffer A K; Tenney D J; Weller S K; Brown J C
Isolation of herpes simplex virus procapsids from cells infected with a protease-deficient mutant virus.
Journal of virology 2000;74(4):1663-73.
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1999: Newcomb W W; Homa F L; Thomsen D R; Trus B L; Cheng N; Steven A; Booy F; Brown J C
Assembly of the herpes simplex virus procapsid from purified components and identification of small complexes containing the major capsid and scaffolding proteins.
Journal of virology 1999;73(5):4239-50.
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1998: Gao M; Robertson B J; McCann P J; O'Boyle D R; Weller S K; Newcomb W W; Brown J C; Weinheimer S P
Functional conservations of the alkaline nuclease of herpes simplex type 1 and human cytomegalovirus.
Virology 1998;249(2):460-70.
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1998: Spencer J V; Newcomb W W; Thomsen D R; Homa F L; Brown J C
Assembly of the herpes simplex virus capsid: preformed triplexes bind to the nascent capsid.
Journal of virology 1998;72(5):3944-51.
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1998: McNab A R; Desai P; Person S; Roof L L; Thomsen D R; Newcomb W W; Brown J C; Homa F L
The product of the herpes simplex virus type 1 UL25 gene is required for encapsidation but not for cleavage of replicated viral DNA.
Journal of virology 1998;72(2):1060-70.
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1997: Spencer J V; Trus B L; Booy F P; Steven A C; Newcomb W W; Brown J C
Structure of the herpes simplex virus capsid: peptide A862-H880 of the major capsid protein is displayed on the rim of the capsomer protrusions.
Virology 1997;228(2):229-35.
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1997: Oien N L; Thomsen D R; Wathen M W; Newcomb W W; Brown J C; Homa F L
Assembly of herpes simplex virus capsids using the human cytomegalovirus scaffold protein: critical role of the C terminus.
Journal of virology 1997;71(2):1281-91.
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1996: Trus B L; Booy F P; Newcomb W W; Brown J C; Homa F L; Thomsen D R; Steven A C
The herpes simplex virus procapsid: structure, conformational changes upon maturation, and roles of the triplex proteins VP19c and VP23 in assembly.
Journal of molecular biology 1996;263(3):447-62.
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1996: Newcomb W W; Homa F L; Thomsen D R; Booy F P; Trus B L; Steven A C; Spencer J V; Brown J C
Assembly of the herpes simplex virus capsid: characterization of intermediates observed during cell-free capsid formation.
Journal of molecular biology 1996;263(3):432-46.
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1996: Belnap D M; Olson N H; Cladel N M; Newcomb W W; Brown J C; Kreider J W; Christensen N D; Baker T S
Conserved features in papillomavirus and polyomavirus capsids.
Journal of molecular biology 1996;259(2):249-63.
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1996: Conway J F; Trus B L; Booy F P; Newcomb W W; Brown J C; Steven A C
Visualization of three-dimensional density maps reconstructed from cryoelectron micrographs of viral capsids.
Journal of structural biology 1996;116(1):200-8.
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1995: Trus B L; Homa F L; Booy F P; Newcomb W W; Thomsen D R; Cheng N; Brown J C; Steven A C
Herpes simplex virus capsids assembled in insect cells infected with recombinant baculoviruses: structural authenticity and localization of VP26.
Journal of virology 1995;69(11):7362-6.
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1995: Thomsen D R; Newcomb W W; Brown J C; Homa F L
Assembly of the herpes simplex virus capsid: requirement for the carboxyl-terminal twenty-five amino acids of the proteins encoded by the UL26 and UL26.5 genes.
Journal of virology 1995;69(6):3690-703.
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1994: Newcomb W W; Homa F L; Thomsen D R; Ye Z; Brown J C
Cell-free assembly of the herpes simplex virus capsid.
Journal of virology 1994;68(9):6059-63.
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1994: Booy F P; Trus B L; Newcomb W W; Brown J C; Conway J F; Steven A C
Finding a needle in a haystack: detection of a small protein (the 12-kDa VP26) in a large complex (the 200-MDa capsid of herpes simplex virus).
Proceedings of the National Academy of Sciences of the United States of America 1994;91(12):5652-6.
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1994: Newcomb W W; Brown J C
Induced extrusion of DNA from the capsid of herpes simplex virus type 1.
Journal of virology 1994;68(1):433-40.
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1993: Conway J F; Trus B L; Booy F P; Newcomb W W; Brown J C; Steven A C
The effects of radiation damage on the structure of frozen hydrated HSV-1 capsids.
Journal of structural biology 1993;111(3):222-33.
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1993: Newcomb W W; Trus B L; Booy F P; Steven A C; Wall J S; Brown J C
Structure of the herpes simplex virus capsid. Molecular composition of the pentons and the triplexes.
Journal of molecular biology 1993;232(2):499-511.
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1992: Trus B L; Newcomb W W; Booy F P; Brown J C; Steven A C
Distinct monoclonal antibodies separately label the hexons or the pentons of herpes simplex virus capsid.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(23):11508-12.
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1992: Mendelson E C; Newcomb W W; Brown J C
Ar+ plasma-induced damage to DNA in bacteriophage lambda: implications for the arrangement of DNA in the phage head.
Journal of virology 1992;66(4):2226-31.
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1991: Baker T S; Newcomb W W; Olson N H; Cowsert L M; Olson C; Brown J C
Structures of bovine and human papillomaviruses. Analysis by cryoelectron microscopy and three-dimensional image reconstruction.
Biophysical journal 1991;60(6):1445-56.
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1991: Booy F P; Newcomb W W; Trus B L; Brown J C; Baker T S; Steven A C
Liquid-crystalline, phage-like packing of encapsidated DNA in herpes simplex virus.
Cell 1991;64(5):1007-15.
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1991: Newcomb W W; Brown J C
Structure of the herpes simplex virus capsid: effects of extraction with guanidine hydrochloride and partial reconstitution of extracted capsids.
Journal of virology 1991;65(2):613-20.
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1990: Baker T S; Newcomb W W; Booy F P; Brown J C; Steven A C
Three-dimensional structures of maturable and abortive capsids of equine herpesvirus 1 from cryoelectron microscopy.
Journal of virology 1990;64(2):563-73.
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1989: Newcomb W W; Brown J C
Use of Ar+ plasma etching to localize structural proteins in the capsid of herpes simplex virus type 1.
Journal of virology 1989;63(11):4697-702.
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1989: Newcomb W W; Brown J C; Booy F P; Steven A C
Nucleocapsid mass and capsomer protein stoichiometry in equine herpesvirus 1: scanning transmission electron microscopic study.
Journal of virology 1989;63(9):3777-83.
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1988: Brown J C; Newcomb W W; Lawrenz-Smith S
pH-dependent accumulation of the vesicular stomatitis virus glycoprotein at the ends of intact virions.
Virology 1988;167(2):625-9.
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1988: Newcomb W W; Brown J C
Use of Ar+ plasma etching to localize structural proteins in viruses: studies with adenovirus 2.
Analytical biochemistry 1988;169(2):279-86.
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1985: Thomas D; Newcomb W W; Brown J C; Wall J S; Hainfeld J F; Trus B L; Steven A C
Mass and molecular composition of vesicular stomatitis virus: a scanning transmission electron microscopy analysis.
Journal of virology 1985;54(2):598-607.
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