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Stuart Newfeld

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Norma T Takaesu; Tetsuro Watabe; Mayu Arase; Kohei Miyazono; Janine C Quijano; Kazumichi Shimizu; Michael J Stinchfield; Stuart J Newfeld
Drosophila CORL is required for Smad2-mediated activation of Ecdysone Receptor expression in the mushroom body.
Michael J Stinchfield; Norma T Takaesu; Nina Tiusanen; Stefano Piccolo; Janine C Quijano; Osamu Shimmi; Ashley M Castillo; Sirio Dupont; Elena Enzo; Stuart J Newfeld
Fat facets deubiquitylation of Medea/Smad4 modulates interpretation of a Dpp morphogen gradient.
Sirio Dupont; Masafumi Inui; Stuart J Newfeld
Regulation of TGF-β signal transduction by mono- and deubiquitylation of Smads.

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All Publications

2012: Norma T Takaesu; Tetsuro Watabe; Mayu Arase; Kohei Miyazono; Janine C Quijano; Kazumichi Shimizu; Michael J Stinchfield; Stuart J Newfeld
Drosophila CORL is required for Smad2-mediated activation of Ecdysone Receptor expression in the mushroom body.
Development (Cambridge, England) 2012;139(18):3392-401.
2012: Michael J Stinchfield; Norma T Takaesu; Nina Tiusanen; Stefano Piccolo; Janine C Quijano; Osamu Shimmi; Ashley M Castillo; Sirio Dupont; Elena Enzo; Stuart J Newfeld
Fat facets deubiquitylation of Medea/Smad4 modulates interpretation of a Dpp morphogen gradient.
Development (Cambridge, England) 2012;139(15):2721-9.
2012: Sirio Dupont; Masafumi Inui; Stuart J Newfeld
Regulation of TGF-β signal transduction by mono- and deubiquitylation of Smads.
FEBS letters 2012;586(14):1913-20.
2012: Robert G Wisotzkey; Charlotte E Konikoff; Stuart J Newfeld
Hippo pathway phylogenetics predicts monoubiquitylation of Salvador and Merlin/Nf2.
PloS one 2012;7(12):e51599.
2011: Sudhir Kumar; Michael McCutchan; Thomas Brody; Christopher Busick; Kailah T Davis; Kristyn Gerold; Shuiwang Ji; Timothy L Karr; Charlotte Konikoff; Sethuraman Panchanathan; Hector Ramos; Bernard Van Emden; Lin-Wei Wu; Jieping Ye; Stuart J Newfeld
FlyExpress: visual mining of spatiotemporal patterns for genes and publications in Drosophila embryogenesis.
Bioinformatics (Oxford, England) 2011;27(23):3319-20.
2011: Janine C Quijano; Michael J Stinchfield; Stuart J Newfeld
Wg signaling via Zw3 and mad restricts self-renewal of sensory organ precursor cells in Drosophila.
Genetics 2011;189(3):809-24.
2010: Charlotte E Konikoff; Robert G Wisotzkey; Michael J Stinchfield; Stuart J Newfeld
Distinct molecular evolutionary mechanisms underlie the functional diversification of the Wnt and TGFbeta signaling pathways.
Journal of molecular evolution 2010;70(4):303-12.
2010: Janine C Quijano; Michael J Stinchfield; Brad Zerlanko; Ying Y Gibbens; Norma T Takaesu; Cathy Hyman-Walsh; David Wotton; Stuart J Newfeld
The Sno oncogene antagonizes Wingless signaling during wing development in Drosophila.
PloS one 2010;5(7):e11619.
2009: Pascal Kahlem; Stuart J Newfeld
Informatics approaches to understanding TGFbeta pathway regulation.
Development (Cambridge, England) 2009;136(22):3729-40.
2009: Sirio Dupont; Anant Mamidi; Michelangelo Cordenonsi; Marco Montagner; Luca Zacchigna; Maddalena Adorno; Graziano Martello; Michael J Stinchfield; Sandra Soligo; Leonardo Morsut; Masafumi Inui; Stefano Moro; Nicola Modena; Francesco Argenton; Stuart J Newfeld; Stefano Piccolo
FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination.
Cell 2009;136(1):123-35.
2008: Charlotte E Konikoff; Robert G Wisotzkey; Stuart J Newfeld
Lysine conservation and context in TGFbeta and Wnt signaling suggest new targets and general themes for posttranslational modification.
Journal of molecular evolution 2008;67(4):323-33.
2008: Joel L Frandsen; Bronwyn Gunn; Selen Catania; Nancy Fossett; Stuart J Newfeld
Salmonella pathogenesis reveals that BMP signaling regulates blood cell homeostasis and immune responses in Drosophila.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(39):14952-7.
2008: Gerard Campbell; Stuart J Newfeld
Current topics in organogenesis and gametogenesis.
Fly 2008;2(3):125-8.
2008: Norma T Takaesu; Denis S Bulanin; Aaron N Johnson; Teresa V Orenic; Stuart J Newfeld
A combinatorial enhancer recognized by Mad, TCF and Brinker first activates then represses dpp expression in the posterior spiracles of Drosophila.
Developmental biology 2008;313(2):829-43.
2007: Stephanie G Hudson; Matthew J Garrett; Joseph W Carlson; Gos Micklem; Susan E Celniker; Elliott S Goldstein; Stuart J Newfeld
Phylogenetic and genomewide analyses suggest a functional relationship between kayak, the Drosophila fos homolog, and fig, a predicted protein phosphatase 2c nested within a kayak intron.
Genetics 2007;177(3):1349-61.
2007: Aaron N Johnson; Lindsey A Burnett; Julia Sellin; Achim Paululat; Stuart J Newfeld
Defective decapentaplegic signaling results in heart overgrowth and reduced cardiac output in Drosophila.
Genetics 2007;176(3):1609-24.
2006: Norma T Takaesu; Cathy Hyman-Walsh; Ying Ye; Robert G Wisotzkey; Michael J Stinchfield; Michael B O'connor; David Wotton; Stuart J Newfeld
dSno facilitates baboon signaling in the Drosophila brain by switching the affinity of Medea away from Mad and toward dSmad2.
Genetics 2006;174(3):1299-313.
2005: Norma T Takaesu; Eric Herbig; David Zhitomersky; Michael B O'Connor; Stuart J Newfeld
DNA-binding domain mutations in SMAD genes yield dominant-negative proteins or a neomorphic protein that can activate WG target genes in Drosophila.
Development (Cambridge, England) 2005;132(21):4883-94.
2003: Cathy A Hyman; Laurent Bartholin; Stuart J Newfeld; David Wotton
Drosophila TGIF proteins are transcriptional activators.
Molecular and cellular biology 2003;23(24):9262-74.
2003: Aaron N Johnson; Casey M Bergman; Martin Kreitman; Stuart J Newfeld
Embryonic enhancers in the dpp disk region regulate a second round of Dpp signaling from the dorsal ectoderm to the mesoderm that represses Zfh-1 expression in a subset of pericardial cells.
Developmental biology 2003;262(1):137-51.
2003: Robert G Wisotzkey; Aaron N Johnson; Norma T Takaesu; Stuart J Newfeld
Alpha/beta hydrolase2, a predicated gene adjacent to mad in Drosophila melanogaster, belongs to a new global multigene family and is associated with obesity.
Journal of molecular evolution 2003;56(3):351-61.
2002: Sudhir Kumar; Karthik Jayaraman; Sethuraman Panchanathan; Rajalakshmi Gurunathan; Ana Marti-Subirana; Stuart J Newfeld
BEST: a novel computational approach for comparing gene expression patterns from early stages of Drosophila melanogaster development.
Genetics 2002;162(4):2037-47.
2002: Norma T Takaesu; Aaron N Johnson; Stuart J Newfeld
Posterior spiracle specific GAL4 lines: new reagents for developmental biology and respiratory physiology.
Genesis (New York, N.Y. : 2000) 2002;34(1-2):16-8.
2002: Norma T Takaesu; Aaron N Johnson; O H Sultani; Stuart J Newfeld
Combinatorial signaling by an unconventional Wg pathway and the Dpp pathway requires Nejire (CBP/p300) to regulate dpp expression in posterior tracheal branches.
Developmental biology 2002;247(2):225-36.
2002: Stuart J Newfeld; Norma T Takaesu
An analysis using the hobo genetic system reveals that combinatorial signaling by the Dpp and Wg pathways regulates dpp expression in leading edge cells of the dorsal ectoderm in Drosophila melanogaster.
Genetics 2002;161(2):685-92.
2002: Aaron N Johnson; Stuart J Newfeld
The TGF-beta family: signaling pathways, developmental roles, and tumor suppressor activities.
TheScientificWorldJournal 2002;2():892-925.
2001: R M Marquez; MA Singer; Norma T Takaesu; W R Waldrip; Y Kraytsberg; Stuart J Newfeld
Transgenic analysis of the Smad family of TGF-beta signal transducers in Drosophila melanogaster suggests new roles and new interactions between family members.
Genetics 2001;157(4):1639-48.
2001: M A Su; Robert G Wisotzkey; Stuart J Newfeld
A screen for modifiers of decapentaplegic mutant phenotypes identifies lilliputian, the only member of the Fragile-X/Burkitt's Lymphoma family of transcription factors in Drosophila melanogaster.
Genetics 2001;157(2):717-25.
2000: Elizabeth L Jockusch; C Nulsen; Stuart J Newfeld; Lisa M Nagy
Leg development in flies versus grasshoppers: differences in dpp expression do not lead to differences in the expression of downstream components of the leg patterning pathway.
Development (Cambridge, England) 2000;127(8):1617-26.
1999: Stuart J Newfeld; Robert G Wisotzkey; Sudhir Kumar
Molecular evolution of a developmental pathway: phylogenetic analyses of transforming growth factor-beta family ligands, receptors and Smad signal transducers.
Genetics 1999;152(2):783-95.
1999: Stuart J Newfeld; Norma T Takaesu
Local transposition of a hobo element within the decapentaplegic locus of Drosophila.
Genetics 1999;151(1):177-87.
1997: Stuart J Newfeld; Arun Mehra; MA Singer; Jeffrey L Wrana; Liliana Attisano; William M Gelbart
Mothers against dpp participates in a DDP/TGF-beta responsive serine-threonine kinase signal transduction cascade.
Development (Cambridge, England) 1997;124(16):3167-76.
1997: Stuart J Newfeld; R W Padgett; S D Findley; B G Richter; M Sanicola; MARGARET DE CUEVAS; William M Gelbart
Molecular evolution at the decapentaplegic locus in Drosophila.
Genetics 1997;145(2):297-309.
1996: Stuart J Newfeld; E H Chartoff; Jonathan M Graff; Douglas A Melton; William M Gelbart
Mothers against dpp encodes a conserved cytoplasmic protein required in DPP/TGF-beta responsive cells.
Development (Cambridge, England) 1996;122(7):2099-108.
1995: Stuart J Newfeld; William M Gelbart
Identification of two Drosophila TGF-beta family members in the grasshopper Schistocerca americana.
Journal of molecular evolution 1995;41(2):155-60.
1995: Jeff Sekelsky; Stuart J Newfeld; Laurel A. Raftery; E H Chartoff; William M Gelbart
Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster.
Genetics 1995;139(3):1347-58.
1994: T J Brummel; Vernon Twombly; Guillermo Marqués; Jeffrey L Wrana; Stuart J Newfeld; Liliana Attisano; Joan Massagué; Michael B O'Connor; William M Gelbart
Characterization and relationship of Dpp receptors encoded by the saxophone and thick veins genes in Drosophila.
Cell 1994;78(2):251-61.