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Peter Newman

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Benjamin E Tourdot; Peter J Newman; Michelle K Brenner; Trudy Holyst; Kathleen C Keough; Debra K Newman
Immunoreceptor Tyrosine-Based Inhibitory Motif (ITIM)-Mediated Inhibitory Signaling Is Regulated by Sequential Phosphorylation Mediated by Distinct Nonreceptor Tyrosine Kinases: A Case Study Involving PECAM-1.
Huiying Zhi; Mortimer Poncz; Lubica Rauova; Brian Boylan; Brian C Cooley; Cunji Gao; Vincent Hayes; Steven E McKenzie; Debra K Newman; Peter J Newman
Cooperative integrin/ITAM signaling in platelets enhances thrombus formation in vitro and in vivo.
Chris John Kuckleburg; Peter J Newman
Neutrophil proteinase 3 acts on protease-activated receptor-2 to enhance vascular endothelial cell barrier function.

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2013: Benjamin E Tourdot; Peter J Newman; Michelle K Brenner; Trudy Holyst; Kathleen C Keough; Debra K Newman
Immunoreceptor Tyrosine-Based Inhibitory Motif (ITIM)-Mediated Inhibitory Signaling Is Regulated by Sequential Phosphorylation Mediated by Distinct Nonreceptor Tyrosine Kinases: A Case Study Involving PECAM-1.
Biochemistry 2013;52(15):2597-608.
2013: Huiying Zhi; Mortimer Poncz; Lubica Rauova; Brian Boylan; Brian C Cooley; Cunji Gao; Vincent Hayes; Steven E McKenzie; Debra K Newman; Peter J Newman
Cooperative integrin/ITAM signaling in platelets enhances thrombus formation in vitro and in vivo.
Blood 2013;121(10):1858-67.
2013: Chris John Kuckleburg; Peter J Newman
Neutrophil proteinase 3 acts on protease-activated receptor-2 to enhance vascular endothelial cell barrier function.
Arteriosclerosis, thrombosis, and vascular biology 2013;33(2):275-84.
2012: Taisuke Kanaji; Takashi Okamura; Jerry Ware; Peter J Newman
GPIbα regulates platelet size by controlling the subcellular localization of filamin.
Blood 2012;119(12):2906-13.
2012: Chris John Kuckleburg; Sentot Santoso; Sarah B Tilkens; Peter J Newman
Proteinase 3 contributes to transendothelial migration of NB1-positive neutrophils.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(5):2419-26.
2012: Jamie R Privratsky; Sarah B Tilkens; Debra K Newman; Peter J Newman
PECAM-1 dampens cytokine levels during LPS-induced endotoxemia by regulating leukocyte trafficking.
Life sciences 2012;90(5-6):177-84.
2011: Cathy Paddock; Betsy L Lytle; Francis C Peterson; Trudy Holyst; Peter J Newman; Brian F Volkman; Debra K Newman
Residues within a lipid-associated segment of the PECAM-1 cytoplasmic domain are susceptible to inducible, sequential phosphorylation.
Blood 2011;117(22):6012-23.
2011: Cunji Gao; Brian Boylan; Juan Fang; David A Wilcox; Debra K Newman; Peter J Newman
Heparin promotes platelet responsiveness by potentiating αIIbβ3-mediated outside-in signaling.
Blood 2011;117(18):4946-52.
2011: Jamie R Privratsky; Cathy M Paddock; Oliver Florey; Debra K Newman; William A Muller; Peter J Newman
Relative contribution of PECAM-1 adhesion and signaling to the maintenance of vascular integrity.
Journal of cell science 2011;124(Pt 9):1477-85.
2011: zhangyin ming; Yu Hu; Jizhou Xiang; Peter Polewski; Peter J Newman; Debra K Newman
Lyn and PECAM-1 function as interdependent inhibitors of platelet aggregation.
Blood 2011;117(14):3903-6.
2010: Daniel W Bougie; Dhirendra Nayak; Brian Boylan; Peter J Newman; Richard H Aster
Drug-dependent clearance of human platelets in the NOD/scid mouse by antibodies from patients with drug-induced immune thrombocytopenia.
Blood 2010;116(16):3033-8.
2010: Jamie R Privratsky; Debra K Newman; Peter J Newman
PECAM-1: conflicts of interest in inflammation.
Life sciences 2010;87(3-4):69-82.
2010: J Crockett; Debra K Newman; Peter J Newman
PECAM-1 functions as a negative regulator of laminin-induced platelet activation.
Journal of thrombosis and haemostasis : JTH 2010;8(7):1584-93.
2010: Behnaz Bayat; Silke Werth; Ulrich J H Sachs; Debra K Newman; Peter J Newman; Sentot Santoso
Neutrophil transmigration mediated by the neutrophil-specific antigen CD177 is influenced by the endothelial S536N dimorphism of platelet endothelial cell adhesion molecule-1.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(7):3889-96.
2010: Jamie R Privratsky; Benjamin E Tourdot; Debra K Newman; Peter J Newman
The anti-inflammatory actions of platelet endothelial cell adhesion molecule-1 do not involve regulation of endothelial cell NF-kappa B.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(6):3157-63.
2009: Tamam Bakchoul; Brian Boylan; Ulrich J H Sachs; Gregor Bein; Changgeng Ruan; Sentot Santoso; Peter J Newman
Blockade of maternal anti-HPA-1a-mediated platelet clearance by an HPA-1a epitope-specific F(ab') in an in vivo mouse model of alloimmune thrombocytopenia.
Transfusion 2009;49(2):265-70.
2008: Reema Goel; Benjamin R Schrank; Shikha Arora; Brian Boylan; Barbara Fleming; Hiroto Miura; Peter J Newman; Robert Molthen; Debra K Newman
Site-specific effects of PECAM-1 on atherosclerosis in LDL receptor-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(11):1996-2002.
2008: Brian Boylan; Cunji Gao; Vipul Rathore; Joan C Gill; Debra K Newman; Peter J Newman
Identification of FcgammaRIIa as the ITAM-bearing receptor mediating alphaIIbbeta3 outside-in integrin signaling in human platelets.
Blood 2008;112(7):2780-6.
2008: Carmen Bergom; Cathy Paddock; Cunji Gao; Trudy Holyst; Debra K Newman; Peter J Newman
An alternatively spliced isoform of PECAM-1 is expressed at high levels in human and murine tissues, and suggests a novel role for the C-terminus of PECAM-1 in cytoprotective signaling.
Journal of cell science 2008;121(Pt 8):1235-42.
2007: Reema Goel; Brian Boylan; Lynn Gruman; Peter J Newman; Paula E North; Debra K Newman
The proinflammatory phenotype of PECAM-1-deficient mice results in atherogenic diet-induced steatohepatitis.
American journal of physiology. Gastrointestinal and liver physiology 2007;293(6):G1205-14.
2007: Ulrich J H Sachs; Luminita-Cornelia Andrei-Selmer; Amudhan Maniar; Timo Weiss; Cathy Paddock; Valeria V Orlova; Eun Young Choi; Peter J Newman; Klaus T Preissner; Triantafyllos Chavakis; Sentot Santoso
The neutrophil-specific antigen CD177 is a counter-receptor for platelet endothelial cell adhesion molecule-1 (CD31).
The Journal of biological chemistry 2007;282(32):23603-12.
2007: Peter J Newman; Richard H Aster; Brian Boylan
Human platelets circulating in mice: applications for interrogating platelet function and survival, the efficacy of antiplatelet therapeutics, and the molecular basis of platelet immunological disorders.
Journal of thrombosis and haemostasis : JTH 2007;5 Suppl 1():305-9.
2007: W Beau Mitchell; Jihong Li; Marta Murcia; Nathalie Valentin; Peter J Newman; Barry S Coller
Mapping early conformational changes in alphaIIb and beta3 during biogenesis reveals a potential mechanism for alphaIIbbeta3 adopting its bent conformation.
Blood 2007;109(9):3725-32.
2007: Jieqing Zhu; Brian Boylan; Bing-Hao Luo; Peter J Newman; Timothy A Springer
Tests of the extension and deadbolt models of integrin activation.
The Journal of biological chemistry 2007;282(16):11914-20.
2007: Vipul Rathore; Masato Okada; Peter J Newman; Debra K Newman
Paxillin family members function as Csk-binding proteins that regulate Lyn activity in human and murine platelets.
The Biochemical journal 2007;403(2):275-81.
2007: Richard H Aster; Peter J Newman
HPA-1a/b(PlA1/A2,Zwa/b): the odyssey of an alloantigen system.
Immunohematology / American Red Cross 2007;23(1):2-8.
2006: Caroline T Sardjono; Stacey N Harbour; Jana C Yip; Cathy Paddock; Susheela Tridandapani; Peter J Newman; Denise E Jackson
Palmitoylation at Cys595 is essential for PECAM-1 localisation into membrane microdomains and for efficient PECAM-1-mediated cytoprotection.
Thrombosis and haemostasis 2006;96(6):756-66.
2006: Carmen Bergom; Reema Goel; Cathy Paddock; Cunji Gao; Debra K Newman; Shigemi Matsuyama; Peter J Newman
The cell-adhesion and signaling molecule PECAM-1 is a molecular mediator of resistance to genotoxic chemotherapy.
Cancer biology & therapy 2006;5(12):1699-707.
2006: Brian Boylan; Michael C Berndt; Mark L Kahn; Peter J Newman
Activation-independent, antibody-mediated removal of GPVI from circulating human platelets: development of a novel NOD/SCID mouse model to evaluate the in vivo effectiveness of anti-human platelet agents.
Blood 2006;108(3):908-14.
2006: Melanie S Novinska; Bradley C Pietz; Thomas M Ellis; Debra K Newman; Peter J Newman
The alleles of PECAM-1.
Gene 2006;376(1):95-101.
2006: Shahrokh Falati; Sonali Patil; Peter L Gross; Michelle Stapleton; Glenn Merrill-Skoloff; Natasha E Barrett; Katherine L Pixton; Hartmut Weiler; Brian C Cooley; Debra K Newman; Peter J Newman; Barbara C Furie; Bruce Furie; Jonathan M Gibbins
Platelet PECAM-1 inhibits thrombus formation in vivo.
Blood 2006;107(2):535-41.
2006: Yanping Liu; Aaron H Bubolz; Yang Shi; Peter J Newman; Debra K Newman; David D Gutterman
Peroxynitrite reduces the endothelium-derived hyperpolarizing factor component of coronary flow-mediated dilation in PECAM-1-knockout mice.
American journal of physiology. Regulatory, integrative and comparative physiology 2006;290(1):R57-65.
2005: Carmen Bergom; Cunji Gao; Peter J Newman
Mechanisms of PECAM-1-mediated cytoprotection and implications for cancer cell survival.
Leukemia & lymphoma 2005;46(10):1409-21.
2005: Matthias Maas; Michelle Stapleton; Carmen Bergom; David L Mattson; Debra K Newman; Peter J Newman
Endothelial cell PECAM-1 confers protection against endotoxic shock.
American journal of physiology. Heart and circulatory physiology 2005;288(1):H159-64.
2004: Brian Boylan; Hong Chen; Vipul Rathore; Cathy Paddock; Michael Salacz; Kenneth D Friedman; Brian Curtis; Michelle Stapleton; Debra K Newman; Mark L Kahn; Peter J Newman
Anti-GPVI-associated ITP: an acquired platelet disorder caused by autoantibody-mediated clearance of the GPVI/FcRgamma-chain complex from the human platelet surface.
Blood 2004;104(5):1350-5.
2004: Vipul Rathore; Demin Wang; Debra K Newman; Peter J Newman
Phospholipase Cgamma2 contributes to stable thrombus formation on VWF.
FEBS letters 2004;573(1-3):26-30.
2003: Matthias Maas; Ronggang Wang; Cathy Paddock; Srigiridhar Kotamraju; Balaraman Kalyanaraman; Peter J Newman; Debra K Newman
Reactive oxygen species induce reversible PECAM-1 tyrosine phosphorylation and SHP-2 binding.
American journal of physiology. Heart and circulatory physiology 2003;285(6):H2336-44.
2003: Vipul Rathore; Michelle Stapleton; Cheryl A Hillery; Robert R Montgomery; Timothy C Nichols; Elizabeth P Merricks; Debra K Newman; Peter J Newman
PECAM-1 negatively regulates GPIb/V/IX signaling in murine platelets.
Blood 2003;102(10):3658-64.
2003: Cunji Gao; Weiyong Sun; Melpo Christofidou-Solomidou; Motoshi Sawada; Debra K Newman; Carmen Bergom; Steven M Albelda; Shigemi Matsuyama; Peter J Newman
PECAM-1 functions as a specific and potent inhibitor of mitochondrial-dependent apoptosis.
Blood 2003;102(1):169-79.
2003: Peter J Newman; Debra K Newman
Signal transduction pathways mediated by PECAM-1: new roles for an old molecule in platelet and vascular cell biology.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(6):953-64.
2003: Julie A Peterson; Contessa E Nyree; Peter J Newman; Richard H Aster
A site involving the "hybrid" and PSI homology domains of GPIIIa (beta 3-integrin subunit) is a common target for antibodies associated with quinine-induced immune thrombocytopenia.
Blood 2003;101(3):937-42.
2002: Qi-Hong Sun; Chao-Yan Liu; Ronggang Wang; Cathy Paddock; Peter J Newman
Disruption of the long-range GPIIIa Cys(5)-Cys(435) disulfide bond results in the production of constitutively active GPIIb-IIIa (alpha(IIb)beta(3)) integrin complexes.
Blood 2002;100(6):2094-101.
2002: Debra K Newman; Sara Hoffman; Srigiridhar Kotamraju; Tieming Zhao; Bassam Wakim; Balaraman Kalyanaraman; Peter J Newman
Nitration of PECAM-1 ITIM tyrosines abrogates phosphorylation and SHP-2 binding.
Biochemical and biophysical research communications 2002;296(5):1171-9.
2001: C Ruiz; C Y Liu; Qi-Hong Sun; Marianne Sigaud-Fiks; Edith Fressinaud; Jean-Yves Muller; P Nurden; A T Nurden; Peter J Newman; Nathalie Valentin
A point mutation in the cysteine-rich domain of glycoprotein (GP) IIIa results in the expression of a GPIIb-IIIa (alphaIIbbeta3) integrin receptor locked in a high-affinity state and a Glanzmann thrombasthenia-like phenotype.
Blood 2001;98(8):2432-41.
2001: MM Farooq; A Serra; Peter J Newman; Robert A Cambria; Gary R Seabrook; Jonathan B Towne; Julie A Freischlag
PECAM-1/IgG attenuates peroxynitrite-mediated extremity reperfusion injury.
Journal of vascular surgery 2001;34(3):555-8.
2001: M Noda; Cathy Paddock; Peter J Newman
Construction and expression of an enzymatically active form of PECAM-1 containing the phosphatase domain of the protein tyrosine phosphatase, SHP-2.
Protein expression and purification 2001;22(1):113-9.
2001: Debra K Newman; C Hamilton; Peter J Newman
Inhibition of antigen-receptor signaling by Platelet Endothelial Cell Adhesion Molecule-1 (CD31) requires functional ITIMs, SHP-2, and p56(lck).
Blood 2001;97(8):2351-7.
2001: S Patil; Debra K Newman; Peter J Newman
Platelet endothelial cell adhesion molecule-1 serves as an inhibitory receptor that modulates platelet responses to collagen.
Blood 2001;97(6):1727-32.
2001: T Zhao; Peter J Newman
Integrin activation by regulated dimerization and oligomerization of platelet endothelial cell adhesion molecule (PECAM)-1 from within the cell.
The Journal of cell biology 2001;152(1):65-73.
2000: CM Ward; A S Kestin; Peter J Newman
A Leu262Pro mutation in the integrin beta(3) subunit results in an alpha(IIb)-beta(3) complex that binds fibrin but not fibrinogen.
Blood 2000;96(1):161-9.
2000: Jing Sun; Cathy Paddock; J Shubert; H B Zhang; K Amin; Peter J Newman; Steven M Albelda
Contributions of the extracellular and cytoplasmic domains of platelet-endothelial cell adhesion molecule-1 (PECAM-1/CD31) in regulating cell-cell localization.
Journal of cell science 2000;113 ( Pt 8)():1459-69.
2000: Marian T Nakada; K Amin; Melpo Christofidou-Solomidou; Christopher D O'Brien; Jing Sun; Indira Gurubhagavatula; G A Heavner; A H Taylor; Cathy Paddock; Qi-Hong Sun; J L Zehnder; Peter J Newman; Steven M Albelda; Horace M DeLisser
Antibodies against the first Ig-like domain of human platelet endothelial cell adhesion molecule-1 (PECAM-1) that inhibit PECAM-1-dependent homophilic adhesion block in vivo neutrophil recruitment.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(1):452-62.
1999: D K Newton-Nash; Peter J Newman
A new role for platelet-endothelial cell adhesion molecule-1 (CD31): inhibition of TCR-mediated signal transduction.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(2):682-8.
1999: Peter J Newman
Switched at birth: a new family for PECAM-1.
The Journal of clinical investigation 1999;103(1):5-9.
1998: R Wang; Peter J Newman
Adhesive and signaling properties of a naturally occurring allele of glycoprotein IIIa with an amino acid substitution within the ligand binding domain-the Pena/Penb platelet alloantigenic epitopes.
Blood 1998;92(9):3260-7.
1998: J P Scott; J P Scott; Y L Chao; Peter J Newman; CM Ward
A frameshift mutation at Gly975 in the transmembrane domain of GPIIb prevents GPIIb-IIIa expression--analysis of two novel mutations in a kindred with type I glanzmann thrombasthenia.
Thrombosis and haemostasis 1998;80(4):546-50.
1998: Julie A Peterson; Gian Paolo Visentin; Peter J Newman; Richard H Aster
A recombinant soluble form of the integrin alpha IIb beta 3 (GPIIb-IIIa) assumes an active, ligand-binding conformation and is recognized by GPIIb-IIIa-specific monoclonal, allo-, auto-, and drug-dependent platelet antibodies.
Blood 1998;92(6):2053-63.
1998: Denise E Jackson; M M White; Lisa K Jennings; Peter J Newman
A Ser162-->Leu mutation within glycoprotein (GP) IIIa (integrin beta3) results in an unstable alphaIIbbeta3 complex that retains partial function in a novel form of type II Glanzmann thrombasthenia.
Thrombosis and haemostasis 1998;80(1):42-8.
1998: Qi-Hong Sun; Cathy Paddock; Gian Paolo Visentin; MM Zukowski; WA Muller; Peter J Newman
Cell surface glycosaminoglycans do not serve as ligands for PECAM-1. PECAM-1 is not a heparin-binding protein.
The Journal of biological chemistry 1998;273(19):11483-90.
1998: D Varon; Denise E Jackson; B Shenkman; Rima Dardik; Ilia Tamarin; N Savion; Peter J Newman
Platelet/endothelial cell adhesion molecule-1 serves as a costimulatory agonist receptor that modulates integrin-dependent adhesion and aggregation of human platelets.
Blood 1998;91(2):500-7.
1997: Peter J Newman
The biology of PECAM-1.
The Journal of clinical investigation 1997;100(11 Suppl):S25-9.
1997: R Wang; S J Shattil; D R Ambruso; Peter J Newman
Truncation of the cytoplasmic domain of beta3 in a variant form of Glanzmann thrombasthenia abrogates signaling through the integrin alpha(IIb)beta3 complex.
The Journal of clinical investigation 1997;100(9):2393-403.
1997: Denise E Jackson; K R Kupcho; Peter J Newman
Characterization of phosphotyrosine binding motifs in the cytoplasmic domain of platelet/endothelial cell adhesion molecule-1 (PECAM-1) that are required for the cellular association and activation of the protein-tyrosine phosphatase, SHP-2.
The Journal of biological chemistry 1997;272(40):24868-75.
1997: Dermot Kenny; Peter J Newman; Patricia A Morateck; Robert R Montgomery
A dinucleotide deletion results in defective membrane anchoring and circulating soluble glycoprotein Ib alpha in a novel form of Bernard-Soulier syndrome.
Blood 1997;90(7):2626-33.
1997: R Wang; J Peterson; R H Aster; Peter J Newman
Disruption of a long-range disulfide bond between residues Cys406 and Cys655 in glycoprotein IIIa does not affect the function of platelet glycoprotein IIb-IIIa.
Blood 1997;90(4):1718-9.
1997: Denise E Jackson; R O Loo; M T Holyst; Peter J Newman
Identification and characterization of functional cation coordination sites in platelet endothelial cell adhesion molecule-1.
Biochemistry 1997;36(31):9395-404.
1997: R J Gumina; Peter J Newman; D Kenny; D C Warltier; G J Gross
The leukocyte cell adhesion cascade and its role in myocardial ischemia-reperfusion injury.
Basic research in cardiology 1997;92(4):201-13.
1997: Denise E Jackson; CM Ward; R Wang; Peter J Newman
The protein-tyrosine phosphatase SHP-2 binds platelet/endothelial cell adhesion molecule-1 (PECAM-1) and forms a distinct signaling complex during platelet aggregation. Evidence for a mechanistic link between PECAM-1- and integrin-mediated cellular signaling.
The Journal of biological chemistry 1997;272(11):6986-93.
1997: R J Gumina; N E Kirschbaum; K Piotrowski; Peter J Newman
Characterization of the human platelet/endothelial cell adhesion molecule-1 promoter: identification of a GATA-2 binding element required for optimal transcriptional activity.
Blood 1997;89(4):1260-9.
1997: Peter J Newman
Platelet alloantigens: cardiovascular as well as immunological risk factors?
Lancet 1997;349(9049):370-1.
1997: Peter J Newman
The biology of PECAM-1.
The Journal of clinical investigation 1997;99(1):3-8.
1996: Richard J Gumina; J el Schultz; Zhenhai Yao; D Kenny; David C Warltier; Peter J Newman; Garrett J Gross
Antibody to platelet/endothelial cell adhesion molecule-1 reduces myocardial infarct size in a rat model of ischemia-reperfusion injury.
Circulation 1996;94(12):3327-33.
1996: D E Jackson; M Poncz; M T Holyst; Peter J Newman
Inherited mutations within the calcium-binding sites of the integrin alpha IIb subunit (platelet glycoprotein IIb). Effects of the amino acid side chain and the amino acid position on cation binding.
European journal of biochemistry / FEBS 1996;240(1):280-7.
1996: Richard J Gumina; N E Kirschbaum; P N Rao; P vanTuinen; Peter J Newman
The human PECAM1 gene maps to 17q23.
Genomics 1996;34(2):229-32.
1996: Q H Sun; Horace M DeLisser; MM Zukowski; C Paddock; Steven M Albelda; Peter J Newman
Individually distinct Ig homology domains in PECAM-1 regulate homophilic binding and modulate receptor affinity.
The Journal of biological chemistry 1996;271(19):11090-8.
1995: Peter J Newman; N Valentin
Human platelet alloantigens: recent findings, new perspectives.
Thrombosis and haemostasis 1995;74(1):234-9.
1995: N Valentin; G P Visentin; Peter J Newman
Involvement of the cysteine-rich domain of glycoprotein IIIa in the expression of the human platelet alloantigen, PlA1: evidence for heterogeneity in the humoral response.
Blood 1995;85(11):3028-33.
1995: D A Wilcox; C M Paddock; S Lyman; J C Gill; Peter J Newman
Glanzmann thrombasthenia resulting from a single amino acid substitution between the second and third calcium-binding domains of GPIIb. Role of the GPIIb amino terminus in integrin subunit association.
The Journal of clinical investigation 1995;95(4):1553-60.
1994: N E Kirschbaum; Richard J Gumina; Peter J Newman
Organization of the gene for human platelet/endothelial cell adhesion molecule-1 shows alternatively spliced isoforms and a functionally complex cytoplasmic domain.
Blood 1994;84(12):4028-37.
1994: A Goldberger; K A Middleton; Peter J Newman
Changes in expression of the cell adhesion molecule PECAM-1 (CD31) during differentiation of human leukemic cell lines.
Tissue antigens 1994;44(5):285-93.
1994: Horace M DeLisser; Peter J Newman; Steven M Albelda
Molecular and functional aspects of PECAM-1/CD31.
Immunology today 1994;15(10):490-5.
1994: N Valentin; Peter J Newman
Human platelet alloantigens.
Current opinion in hematology 1994;1(5):381-7.
1994: H Scott Baldwin; H M Shen; H C Yan; Horace M DeLisser; A Chung; CS Mickanin; T Trask; N E Kirschbaum; Peter J Newman; Steven M Albelda
Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development.
Development (Cambridge, England) 1994;120(9):2539-53.
1994: A Goldberger; K A Middleton; J A Oliver; C Paddock; H C Yan; Horace M DeLisser; Steven M Albelda; Peter J Newman
Biosynthesis and processing of the cell adhesion molecule PECAM-1 includes production of a soluble form.
The Journal of biological chemistry 1994;269(25):17183-91.
1994: Peter J Newman
Nomenclature of human platelet alloantigens: a problem with the HPA system?
Blood 1994;83(6):1447-51.
1994: D A Wilcox; J L Wautier; D Pidard; Peter J Newman
A single amino acid substitution flanking the fourth calcium binding domain of alpha IIb prevents maturation of the alpha IIb beta 3 integrin complex.
The Journal of biological chemistry 1994;269(6):4450-7.
1994: Mortimer Poncz; S Rifat; Barry S Coller; Peter J Newman; Sanford J Shattil; T Parrella; Paolo Fortina; Joel S Bennett
Glanzmann thrombasthenia secondary to a Gly273-->Asp mutation adjacent to the first calcium-binding domain of platelet glycoprotein IIb.
The Journal of clinical investigation 1994;93(1):172-9.
1993: R Wang; Janice G McFarland; riitta marjut kekomaki; Peter J Newman
Amino acid 489 is encoded by a mutational "hot spot" on the beta 3 integrin chain: the CA/TU human platelet alloantigen system.
Blood 1993;82(11):3386-91.
1993: Horace M DeLisser; H C Yan; Peter J Newman; William A Muller; CA Buck; Steven M Albelda
Platelet/endothelial cell adhesion molecule-1 (CD31)-mediated cellular aggregation involves cell surface glycosaminoglycans.
The Journal of biological chemistry 1993;268(21):16037-46.
1993: Janice G McFarland; V Blanchette; J Collins; Peter J Newman; R Wang; Richard H Aster
Neonatal alloimmune thrombocytopenia due to a new platelet-specific alloantibody.
Blood 1993;81(12):3318-23.
1993: Horace M DeLisser; Peter J Newman; Steven M Albelda
Platelet endothelial cell adhesion molecule (CD31).
Current topics in microbiology and immunology 1993;184():37-45.
1992: R Wang; K Furihata; Janice G McFarland; K Friedman; Richard H Aster; Peter J Newman
An amino acid polymorphism within the RGD binding domain of platelet membrane glycoprotein IIIa is responsible for the formation of the Pena/Penb alloantigen system.
The Journal of clinical investigation 1992;90(5):2038-43.
1992: Peter J Newman; C A Hillery; R Albrecht; Leslie V Parise; M C Berndt; A V Mazurov; L C Dunlop; J Zhang; S E Rittenhouse
Activation-dependent changes in human platelet PECAM-1: phosphorylation, cytoskeletal association, and surface membrane redistribution.
The Journal of cell biology 1992;119(1):239-46.
1992: Thomas J Kunicki; Peter J Newman
The molecular immunology of human platelet proteins.
Blood 1992;80(6):1386-404.
1992: William A Muller; M E Berman; Peter J Newman; Horace M DeLisser; Steven M Albelda
A heterophilic adhesion mechanism for platelet/endothelial cell adhesion molecule 1 (CD31).
The Journal of experimental medicine 1992;175(5):1401-4.
1992: Peter J Newman; S M Albelda
Cellular and molecular aspects of PECAM-1.
Nouvelle revue française d'hématologie 1992;34 Suppl():S9-13.
1992: Maryam Yassai; Janice G McFarland; D Newton-Nash; Peter J Newman; D D Eckels; Jack Gorski
T cell receptor and alloimmune thrombocytopenias: a model for autoimmune diseases?
Annales de médecine interne 1992;143(6):365-70.
1991: Janice G McFarland; Richard H Aster; J B Bussel; J G Gianopoulos; R S Derbes; Peter J Newman
Prenatal diagnosis of neonatal alloimmune thrombocytopenia using allele-specific oligonucleotide probes.
Blood 1991;78(9):2276-82.
1991: Steven M Albelda; William A Muller; CA Buck; Peter J Newman
Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule.
The Journal of cell biology 1991;114(5):1059-68.
1991: A Goldberger; M Kolodziej; M Poncz; J S Bennett; Peter J Newman
Effect of single amino acid substitutions on the formation of the PlA and Bak alloantigenic epitopes.
Blood 1991;78(3):681-7.
1991: G P Visentin; Peter J Newman; Richard H Aster
Characteristics of quinine- and quinidine-induced antibodies specific for platelet glycoproteins IIb and IIIa.
Blood 1991;77(12):2668-76.
1991: Peter J Newman; U Seligsohn; S Lyman; Barry S Coller
The molecular genetic basis of Glanzmann thrombasthenia in the Iraqi-Jewish and Arab populations in Israel.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(8):3160-4.
1991: C D Burk; Peter J Newman; S Lyman; J Gill; Barry S Coller; Mortimer Poncz
A deletion in the gene for glycoprotein IIb associated with Glanzmann's thrombasthenia.
The Journal of clinical investigation 1991;87(1):270-6.
1990: Gian Paolo Visentin; K Wolfmeyer; Peter J Newman; Richard H Aster
Detection of drug-dependent, platelet-reactive antibodies by antigen-capture ELISA and flow cytometry.
Transfusion 1990;30(8):694-700.
1990: S Lyman; Richard H Aster; G P Visentin; Peter J Newman
Polymorphism of human platelet membrane glycoprotein IIb associated with the Baka/Bakb alloantigen system.
Blood 1990;75(12):2343-8.
1990: Mortimer Poncz; Peter J Newman
Analysis of rodent platelet glycoprotein IIb: evidence for evolutionarily conserved domains and alternative proteolytic processing.
Blood 1990;75(6):1282-9.
1990: Peter J Newman; M C Berndt; J Gorski; G C White; S Lyman; C Paddock; W A Muller
PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily.
Science (New York, N.Y.) 1990;247(4947):1219-22.
1989: Peter J Newman; R S Derbes; Richard H Aster
The human platelet alloantigens, PlA1 and PlA2, are associated with a leucine33/proline33 amino acid polymorphism in membrane glycoprotein IIIa, and are distinguishable by DNA typing.
The Journal of clinical investigation 1989;83(5):1778-81.
1988: Peter J Newman; J Gorski; G C White; S Gidwitz; C J Cretney; Richard H Aster
Enzymatic amplification of platelet-specific messenger RNA using the polymerase chain reaction.
The Journal of clinical investigation 1988;82(2):739-43.