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Michael Newton

Research Profile

Chemicals & Drugs

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Publications

TOP 3
Paul E Knight; Fridrun Podczeck; J Michael Newton
The rheological properties of modified microcrystalline cellulose containing high levels of model drugs.
J Michael Newton; Mariana Reis Pinto; Fridrun Podczeck
The preparation of pellets containing a surfactant or a mixture of mono- and di-gylcerides by extrusion/spheronization.
Abraham B Bashaiwoldu; Fridrun Podczeck; J Michael Newton
Factorial designed experiment to study the effects of excipients on the mechanical properties of pellets.

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All Publications

2009: Paul E Knight; Fridrun Podczeck; J Michael Newton
The rheological properties of modified microcrystalline cellulose containing high levels of model drugs.
Journal of pharmaceutical sciences 2009;98(6):2160-9.
2007: J Michael Newton; Mariana Reis Pinto; Fridrun Podczeck
The preparation of pellets containing a surfactant or a mixture of mono- and di-gylcerides by extrusion/spheronization.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2007;30(3-4):333-42.
2006: Abraham B Bashaiwoldu; Fridrun Podczeck; J Michael Newton
Factorial designed experiment to study the effects of excipients on the mechanical properties of pellets.
The Journal of pharmacy and pharmacology 2006;58(10):1305-9.
2005: J Michael Newton; M Bazzigialuppi; Fridrun Podczeck; Steven Booth; Ashley Clarke
The rheological properties of self-emulsifying systems, water and microcrystalline cellulose.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2005;26(2):176-83.
2005: Jittima Chatchawalsaisin; Fridrun Podczeck; J Michael Newton
The preparation by extrusion/spheronization and the properties of pellets containing drugs, microcrystalline cellulose and glyceryl monostearate.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2005;24(1):35-48.
2004: Jittima Chatchawalsaisin; Fridrun Podczeck; J Michael Newton
The influence of chitosan and sodium alginate and formulation variables on the formation and drug release from pellets prepared by extrusion/spheronisation.
International journal of pharmaceutics 2004;275(1-2):41-60.
2004: Abraham B Bashaiwoldu; Fridrun Podczeck; J Michael Newton
The application of non-contact laser profilometry to the determination of permanent structural change induced by compaction of pellets II. Pellets dried by different techniques.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2004;22(1):55-61.
2004: Abraham B Bashaiwoldu; Fridrun Podczeck; J Michael Newton
Application of dynamic mechanical analysis (DMA) to the determination of the mechanical properties of coated pellets.
International journal of pharmaceutics 2004;274(1-2):53-63.
2004: Lee F Siew; Sit-Ming Man; J Michael Newton; Abdul W Basit
Amylose formulations for drug delivery to the colon: a comparison of two fermentation models to assess colonic targeting performance in vitro.
International journal of pharmaceutics 2004;273(1-2):129-34.
2004: Abdul W Basit; Fridrun Podczeck; J Michael Newton; Wendy A Waddington; Peter J Ell; Larry F Lacey
The use of formulation technology to assess regional gastrointestinal drug absorption in humans.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2004;21(2-3):179-89.
2004: Abraham B Bashaiwoldu; Fridrun Podczeck; J Michael Newton
The application of non-contact laser profilometry to the determination of permanent structural changes induced by compaction of pellets. I. Pellets of different composition.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2004;21(2-3):143-54.
2004: Abraham B Bashaiwoldu; Fridrun Podczeck; J Michael Newton
A study on the effect of drying techniques on the mechanical properties of pellets and compacted pellets.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2004;21(2-3):119-29.
2004: Abraham B Bashaiwoldu; Fridrun Podczeck; J Michael Newton
Application of dynamic mechanical analysis (DMA) to determine the mechanical properties of pellets.
International journal of pharmaceutics 2004;269(2):329-42.
2002: C W Leong; J Michael Newton; Abdul W Basit; Fridrun Podczeck; J H Cummings; S G Ring
The formation of colonic digestible films of amylose and ethylcellulose from aqueous dispersions at temperatures below 37 degrees C.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2002;54(3):291-7.
2002: K A MacRitchie; J Michael Newton; R C Rowe
The evaluation of the rheological properties of lactose/microcrystalline cellulose and water mixtures by controlled stress rheometry and the relationship to the production of spherical pellets by extrusion/spheronization.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2002;17(1-2):43-50.
2002: Catherine Tuleu; Abdul W Basit; Wendy A Waddington; Peter J Ell; J Michael Newton
Colonic delivery of 4-aminosalicylic acid using amylose-ethylcellulose-coated hydroxypropylmethylcellulose capsules.
Alimentary pharmacology & therapeutics 2002;16(10):1771-9.
2002: Abdul W Basit; Fridrun Podczeck; J Michael Newton; Wendy A Waddington; Peter J Ell; Larry F Lacey
Influence of polyethylene glycol 400 on the gastrointestinal absorption of ranitidine.
Pharmaceutical research 2002;19(9):1368-74.
2002: SV Lafferty; J Michael Newton; Fridrun Podczeck
Kinetic examination of the mechanical transition of polymethyl methacrylate films prepared from aqueous dispersions.
International journal of pharmaceutics 2002;239(1-2):179-83.
2002: Ranjana Chopra; Göran Alderborn; Fridrun Podczeck; J Michael Newton
The influence of pellet shape and surface properties on the drug release from uncoated and coated pellets.
International journal of pharmaceutics 2002;239(1-2):171-8.
2002: SV Lafferty; J Michael Newton; Fridrun Podczeck
Characterisation of the mechanical properties of polymer films formed from aqueous polymer dispersions by creep testing.
International journal of pharmaceutics 2002;239(1-2):143-8.
2002: S Boutell; J Michael Newton; J R Bloor; G Hayes
The influence of liquid binder on the liquid mobility and preparation of spherical granules by the process of extrusion/spheronization.
International journal of pharmaceutics 2002;238(1-2):61-76.
2002: Ranjana Chopra; Fridrun Podczeck; J Michael Newton; Göran Alderborn
The influence of pellet shape and film coating on the filling of pellets into hard shell capsules.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2002;53(3):327-33.
2002: Abdul W Basit; J Michael Newton; Larry F Lacey
Susceptibility of the H2-receptor antagonists cimetidine, famotidine and nizatidine, to metabolism by the gastrointestinal microflora.
International journal of pharmaceutics 2002;237(1-2):23-33.
2002: SV Lafferty; J Michael Newton; Fridrun Podczeck
Dynamic mechanical thermal analysis studies of polymer films prepared from aqueous dispersion.
International journal of pharmaceutics 2002;235(1-2):107-11.
2002: Ranjana Chopra; Göran Alderborn; J Michael Newton; Fridrun Podczeck
The influence of film coating on pellet properties.
Pharmaceutical development and technology 2002;7(1):59-68.
2002: G Tomer; Fridrun Podczeck; J Michael Newton
The influence of model drugs on the preparation of pellets by extrusion/spheronization: II. Spheronization parameters.
International journal of pharmaceutics 2002;231(1):107-19.
2001: Ranjana Chopra; J Michael Newton; Göran Alderborn; Fridrun Podczeck
Preparation of pellets of different shape and their characterization.
Pharmaceutical development and technology 2001;6(4):495-503.
2001: Abdul W Basit; J Michael Newton; M D Short; Wendy A Waddington; Peter J Ell; Larry F Lacey
The effect of polyethylene glycol 400 on gastrointestinal transit: implications for the formulation of poorly-water soluble drugs.
Pharmaceutical research 2001;18(8):1146-50.
2001: G Tomer; Fridrun Podczeck; J Michael Newton
The influence of type and quantity of model drug on the extrusion/spheronization of mixtures with microcrystalline cellulose. I. Extrusion parameters.
International journal of pharmaceutics 2001;217(1-2):237-48.
2001: G Tomer; H Patel; Fridrun Podczeck; J Michael Newton
Measuring the water retention capacities (MRC) of different microcrystalline cellulose grades.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2001;12(3):321-5.
2000: Fridrun Podczeck; J Michael Newton
Powder and capsule filling properties of lubricated granulated cellulose powder.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2000;50(3):373-7.
2000: Lee F Siew; Abdul W Basit; J Michael Newton
The properties of amylose-ethylcellulose films cast from organic-based solvents as potential coatings for colonic drug delivery.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2000;11(2):133-9.
2000: Lee F Siew; Abdul W Basit; J Michael Newton
The potential of organic-based amylose-ethylcellulose film coatings as oral colon-specific drug delivery systems.
AAPS PharmSciTech 2000;1(3):E22.
2000: Y S Lee; R Poynter; Fridrun Podczeck; J Michael Newton
Development of a dual approach to assess powder flow from avalanching behavior.
AAPS PharmSciTech 2000;1(3):E21.
1999: Fridrun Podczeck; S R Rahman; J Michael Newton
Evaluation of a standardised procedure to assess the shape of pellets using image analysis.
International journal of pharmaceutics 1999;192(2):123-38.
1999: T Hamaura; J Michael Newton
Interaction between water and poly(vinylpyrrolidone) containing polyethylene glycol.
Journal of pharmaceutical sciences 1999;88(11):1228-33.
1999: G Tomer; Michael D Mantle; L F Gladden; J Michael Newton
Measuring water distribution in extrudates using magnetic resonance imaging (MRI).
International journal of pharmaceutics 1999;189(1):19-28.
1999: Fridrun Podczeck; S Blackwell; M Gold; J Michael Newton
The filling of granules into hard gelatine capsules.
International journal of pharmaceutics 1999;188(1):59-69.
1999: G Tomer; J Michael Newton
A centrifuge technique for the evaluation of the extent of water movement in wet powder masses.
International journal of pharmaceutics 1999;188(1):31-8.
1999: Fridrun Podczeck; J Michael Newton
Powder filling into hard gelatine capsules on a tamp filling machine.
International journal of pharmaceutics 1999;185(2):237-54.
1999: G Tomer; J Michael Newton
Water movement evaluation during extrusion of wet powder masses by collecting extrudate fractions.
International journal of pharmaceutics 1999;182(1):71-7.
1999: G Tomer; J Michael Newton; Paul Kinchesh
Magnetic resonance imaging (MRI) as a method to investigate movement of water during the extrusion of pastes.
Pharmaceutical research 1999;16(5):666-71.
1999: C Lustig-Gustafsson; H Kaur Johal; Fridrun Podczeck; J Michael Newton
The influence of water content and drug solubility on the formulation of pellets by extrusion and spheronisation.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 1999;8(2):147-52.
1999: Fridrun Podczeck; N J Course; J Michael Newton
Determination of the gastric emptying of solid dosage forms using gamma-scintigraphy: a problem of image timing and mathematical analysis.
European journal of nuclear medicine 1999;26(4):373-8.
1999: Abdul W Basit; J Michael Newton; Larry F Lacey
Formulation of ranitidine pellets by extrusion-spheronization with little or no microcrystalline cellulose.
Pharmaceutical development and technology 1999;4(4):499-505.
1998: A E Lundqvist; Fridrun Podczeck; J Michael Newton
Compaction of, and drug release from, coated drug pellets mixed with other pellets.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 1998;46(3):369-79.
1998: M C Ambros; Fridrun Podczeck; H Podczeck; J Michael Newton
The characterization of the mechanical strength of chewable tablets.
Pharmaceutical development and technology 1998;3(4):509-15.
1998: M A Al-Nasassrah; Fridrun Podczeck; J Michael Newton
The effect of an increase in chain length on the mechanical properties of polyethylene glycols.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 1998;46(1):31-8.
1996: J Hogan; P I Shue; Fridrun Podczeck; J Michael Newton
Investigations into the relationship between drug properties, filling, and the release of drugs from hard gelatin capsules using multivariate statistical analysis.
Pharmaceutical research 1996;13(6):944-9.
1995: Fridrun Podczeck; J Michael Newton
Development of an ultracentrifuge technique to determine the adhesion and friction properties between particles and surfaces.
Journal of pharmaceutical sciences 1995;84(9):1067-71.
1995: W Sutananta; Duncan Q M Craig; J Michael Newton
An investigation into the effects of preparation conditions and storage on the rate of drug release from pharmaceutical glyceride bases.
The Journal of pharmacy and pharmacology 1995;47(5):355-9.
1995: Fridrun Podczeck; J Michael Newton; Kah Hay Yuen
The description of the gastrointestinal transit of pellets assessed by gamma scintigraphy using statistical moments.
Pharmaceutical research 1995;12(3):376-9.
1995: W Sutananta; Duncan Q M Craig; J Michael Newton
An evaluation of the mechanisms of drug release from glyceride bases.
The Journal of pharmacy and pharmacology 1995;47(3):182-7.
1994: Fridrun Podczeck; J Michael Newton
A shape factor to characterize the quality of spheroids.
The Journal of pharmacy and pharmacology 1994;46(2):82-5.
1993: Kah Hay Yuen; A A Desmukh; J Michael Newton
In vivo/in vitro correlation of experimental sustained-release theophylline formulations.
Pharmaceutical research 1993;10(4):588-92.
1992: N J Course; J Michael Newton; M D Short
Stomach outline visualization in gastrointestinal transit studies using scintigraphy.
The Journal of pharmacy and pharmacology 1992;44(2):127-9.
1991: K G Pitt; J Michael Newton; P Stanley
Effects of compaction variables on porosity and material tensile strength of convex-faced aspirin tablets.
The Journal of pharmacy and pharmacology 1991;43(4):219-25.
1990: J E Devereux; J Michael Newton; M B Short
The influence of density on the gastrointestinal transit of pellets.
The Journal of pharmacy and pharmacology 1990;42(7):500-1.
1989: K G Pitt; J Michael Newton; R Richardson; P Stanley
The material tensile strength of convex-faced aspirin tablets.
The Journal of pharmacy and pharmacology 1989;41(5):289-92.
1989: K E Fielden; J Michael Newton; R C Rowe
The effect of lactose particle size on the extrusion properties of microcrystalline cellulose-lactose mixtures.
The Journal of pharmacy and pharmacology 1989;41(4):217-21.
1989: I Nikolakakis; J Michael Newton
Solid state adsorption of antibiotics onto sorbitol.
The Journal of pharmacy and pharmacology 1989;41(3):145-8.
1988: K E Fielden; J Michael Newton; P O'Brien; R C Rowe
Thermal studies on the interaction of water and microcrystalline cellulose.
The Journal of pharmacy and pharmacology 1988;40(10):674-8.
1988: A B Mashadi; J Michael Newton
Determination of the critical stress intensity factor (KIC) of compacted pharmaceutical powders by the double torsion method.
The Journal of pharmacy and pharmacology 1988;40(9):597-600.
1987: A B Mashadi; J Michael Newton
The characterization of the mechanical properties of microcrystalline cellulose: a fracture mechanics approach.
The Journal of pharmacy and pharmacology 1987;39(12):961-5.
1987: S W Booth; J Michael Newton
Experimental investigation of adhesion between powders and surfaces.
The Journal of pharmacy and pharmacology 1987;39(9):679-84.