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Robert Newton

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Xiangdong Liu; Cindy Marando; Robert C Newton; Qian Wang; Richard Wynn; Meizhong Xu; Gengjie Yang; Wenqing Yao; Jincong Zhuo; Elham Behshad; Jason Boer; Sharon Diamond; Jordan S Fridman; Leslie M Hall; Chunhong He; Holly K Koblish; Yu Li; Peggy A Scherle
A novel kinase inhibitor, INCB28060, blocks c-MET-dependent signaling, neoplastic activities, and cross-talk with EGFR and HER-3.
Jordan S Fridman; Steven M Friedman; Patrick Haley; Denise Hertel; Gregory Hollis; Brian Metcalf; Claire L Neilan; Robert C Newton; James D Rodgers; Peggy A Scherle; Stacey Shepard; Jack Shi; Beth Thomas; Timothy C Burn; Paul Collier; Robert Collins; Nancy Contel; Swamy Yeleswaram; Kris Vaddi
Preclinical evaluation of local JAK1 and JAK2 inhibition in cutaneous inflammation.
Niu Shin; Frédéric Baribaud; Kathy Wang; Genjie Yang; Rich Wynn; Maryanne B Covington; Patricia Feldman; Karen B Gallagher; Lynn M Leffet; Yvonne Y Lo; Anlai Wang; Chu-Biao Xue; Robert C Newton; Peggy A Scherle
Pharmacological characterization of INCB3344, a small molecule antagonist of human CCR2.

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All Publications

2011: Xiangdong Liu; Cindy Marando; Robert C Newton; Qian Wang; Richard Wynn; Meizhong Xu; Gengjie Yang; Wenqing Yao; Jincong Zhuo; Elham Behshad; Jason Boer; Sharon Diamond; Jordan S Fridman; Leslie M Hall; Chunhong He; Holly K Koblish; Yu Li; Peggy A Scherle
A novel kinase inhibitor, INCB28060, blocks c-MET-dependent signaling, neoplastic activities, and cross-talk with EGFR and HER-3.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(22):7127-38.
2011: Jordan S Fridman; Steven M Friedman; Patrick Haley; Denise Hertel; Gregory Hollis; Brian Metcalf; Claire L Neilan; Robert C Newton; James D Rodgers; Peggy A Scherle; Stacey Shepard; Jack Shi; Beth Thomas; Timothy C Burn; Paul Collier; Robert Collins; Nancy Contel; Swamy Yeleswaram; Kris Vaddi
Preclinical evaluation of local JAK1 and JAK2 inhibition in cutaneous inflammation.
The Journal of investigative dermatology 2011;131(9):1838-44.
2009: Niu Shin; Frédéric Baribaud; Kathy Wang; Genjie Yang; Rich Wynn; Maryanne B Covington; Patricia Feldman; Karen B Gallagher; Lynn M Leffet; Yvonne Y Lo; Anlai Wang; Chu-Biao Xue; Robert C Newton; Peggy A Scherle
Pharmacological characterization of INCB3344, a small molecule antagonist of human CCR2.
Biochemical and biophysical research communications 2009;387(2):251-5.
2008: Zhonghui Lu; Gregory R Ott; Rajan Anand; Rui-Qin Liu; Maryanne B Covington; Kris Vaddi; Mingxin Qian; Robert C Newton; David D Christ; James M Trzaskos; James J-W Duan
Potent, selective, orally bioavailable inhibitors of tumor necrosis factor-alpha converting enzyme (TACE): discovery of indole, benzofuran, imidazopyridine and pyrazolopyridine P1' substituents.
Bioorganic & medicinal chemistry letters 2008;18(6):1958-62.
2008: Gregory R Ott; Naoyuki Asakawa; Zhonghui Lu; Rajan Anand; Rui-Qin Liu; Maryanne B Covington; Kris Vaddi; Mingxin Qian; Robert C Newton; David D Christ; James M Trzaskos; James J-W Duan
Potent, exceptionally selective, orally bioavailable inhibitors of TNF-alpha Converting Enzyme (TACE): novel 2-substituted-1H-benzo[d]imidazol-1-yl)methyl)benzamide P1' substituents.
Bioorganic & medicinal chemistry letters 2008;18(5):1577-82.
2008: Gregory R Ott; Naoyuki Asakawa; Rui-Qin Liu; Maryanne B Covington; Mingxin Qian; Kris Vaddi; Robert C Newton; James M Trzaskos; David D Christ; Laurine Galya; Thomas Scholz; Will Marshall; James J-W Duan
Alpha,Beta-cyclic-beta-benzamido hydroxamic acids: Novel oxaspiro[4.4]nonane templates for the discovery of potent, selective, orally bioavailable inhibitors of tumor necrosis factor-alpha converting enzyme (TACE).
Bioorganic & medicinal chemistry letters 2008;18(4):1288-92.
2008: Gregory R Ott; Naoyuki Asakawa; Zhonghui Lu; Rui-Qin Liu; Maryanne B Covington; Kris Vaddi; Mingxin Qian; Robert C Newton; David D Christ; James M Traskos; Carl P Decicco; James J-W Duan
Alpha,beta-cyclic-beta-benzamido hydroxamic acids: novel templates for the design, synthesis, and evaluation of selective inhibitors of TNF-alpha converting enzyme (TACE).
Bioorganic & medicinal chemistry letters 2008;18(2):694-9.
2008: James J-W Duan; Lihua Chen; Zhonghui Lu; Chu-Biao Xue; Rui-Qin Liu; Maryanne B Covington; Mingxin Qian; Zelda R Wasserman; Kris Vaddi; David D Christ; James M Trzaskos; Robert C Newton; Carl P Decicco
Discovery of beta-benzamido hydroxamic acids as potent, selective, and orally bioavailable TACE inhibitors.
Bioorganic & medicinal chemistry letters 2008;18(1):241-6.
2007: Mingxin Qian; Stephen A Bai; Bernice Brogdon; Jing-Tao Wu; Rui-Qin Liu; Maryanne B Covington; Kris Vaddi; Robert C Newton; Michael Fossler; C Edwin Garner; Yuzhong Deng; Thomas Maduskuie; James M Trzaskos; James J-W Duan; Carl P Decicco; David D Christ
Pharmacokinetics and pharmacodynamics of DPC 333 ((2R)-2-((3R)-3-amino-3{4-[2-methyl-4-quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4-methylpentanamide)), a potent and selective inhibitor of tumor necrosis factor alpha-converting enzyme in rodents, dogs, chimpanzees, and humans.
Drug metabolism and disposition: the biological fate of chemicals 2007;35(10):1916-25.
2007: James R Pruitt; Douglas G Batt; Dean A Wacker; Lori L Bostrom; Shon K Booker; Erin McLaughlin; Gregory C Houghton; Jeffrey G Varnes; David D Christ; Maryanne B Covington; Anuk M Das; Paul Davies; Danielle Graden; Ilona Kariv; Yevgeniya Orlovsky; Nicole C Stowell; Kris Vaddi; Eric A Wadman; Patricia K Welch; Swamy Yeleswaram; Kimberly A Solomon; Robert C Newton; Carl P Decicco; Percy H Carter; Soo S Ko
CC chemokine receptor-3 (CCR3) antagonists: improving the selectivity of DPC168 by reducing central ring lipophilicity.
Bioorganic & medicinal chemistry letters 2007;17(11):2992-7.
2007: Xiao-Tao Chen; Bahman Ghavimi; Ronald L Corbett; Chu-Biao Xue; Rui-Qin Liu; Maryanne B Covington; Mingxin Qian; Kris Vaddi; David D Christ; Karl D Hartman; Maria D Ribadeneira; James M Trzaskos; Robert C Newton; Carl P Decicco; James J-W Duan
A new 4-(2-methylquinolin-4-ylmethyl)phenyl P1' group for the beta-amino hydroxamic acid derived TACE inhibitors.
Bioorganic & medicinal chemistry letters 2007;17(7):1865-70.
2007: Jordan S Fridman; Eian Caulder; Michael Hansbury; Xiangdong Liu; Genjie Yang; Qian Wang; Yvonne Lo; Bin-Bing S Zhou; Maxwell Pan; Sufi Thomas; Jennifer Rubin Grandis; Jincong Zhuo; Wenqing Yao; Robert C Newton; Steven M Friedman; Peggy A Scherle; Kris Vaddi
Selective inhibition of ADAM metalloproteases as a novel approach for modulating ErbB pathways in cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(6):1892-902.
2006: Paul S Watson; Bin Jiang; Kim Harrison; Naoyuki Asakawa; Patricia K Welch; Maryanne B Covington; Nicole C Stowell; Eric A Wadman; Paul Davies; Kimberly A Solomon; Robert C Newton; George L Trainor; Steven M Friedman; Carl P Decicco; Soo S Ko
2,4-Disubstituted piperidines as selective CC chemokine receptor 3 (CCR3) antagonists: synthesis and selectivity.
Bioorganic & medicinal chemistry letters 2006;16(21):5695-9.
2006: Bin-Bing S Zhou; Michael Peyton; Biao He; Changnian Liu; Luc Girard; Eian Caudler; Yvonne Lo; Frédéric Baribaud; Iwao Mikami; Noemi Reguart; Gengjie Yang; Yanlong Li; Wenqing Yao; Kris Vaddi; Adi F Gazdar; Steven M Friedman; David M Jablons; Robert C Newton; Jordan S Fridman; John D Minna; Peggy A Scherle
Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer.
Cancer cell 2006;10(1):39-50.
2006: Anuk M Das; Kris Vaddi; Kimberly A Solomon; Candice Krauthauser; Xiaosui Jiang; Kim McIntyre; Xiao Xia Yang; Eric A Wadman; Patricia K Welch; Maryanne B Covington; Danielle Graden; Krishnaswamy Yeleswaram; James M Trzaskos; Robert C Newton; Sandhya Mandlekar; Soo S Ko; Percy H Carter; Paul Davies
Selective inhibition of eosinophil influx into the lung by small molecule CC chemokine receptor 3 antagonists in mouse models of allergic inflammation.
The Journal of pharmacology and experimental therapeutics 2006;318(1):411-7.
2006: Xiangdong Liu; Jordan S Fridman; Qian Wang; Eian Caulder; Gengjie Yang; Maryanne B Covington; Changnian Liu; Cindy Marando; Jincong Zhuo; Yanlong Li; Wenqing Yao; Kris Vaddi; Robert C Newton; Peggy A Scherle; Steven M Friedman
Selective inhibition of ADAM metalloproteases blocks HER-2 extracellular domain (ECD) cleavage and potentiates the anti-tumor effects of trastuzumab.
Cancer biology & therapy 2006;5(6):648-56.
2006: John L Gilmore; Bryan W King; Cathy Harris; Thomas Maduskuie; Stephen E Mercer; Rui-Qin Liu; Maryanne B Covington; Mingxin Qian; Maria D Ribadeneria; Kris Vaddi; James M Trzaskos; Robert C Newton; Carl P Decicco; James J-W Duan
Synthesis and structure-activity relationship of a novel, achiral series of TNF-alpha converting enzyme inhibitors.
Bioorganic & medicinal chemistry letters 2006;16(10):2699-704.
2005: Carrie M Brodmerkel; Reid Huber; Maryanne B Covington; Sharon Diamond; Leslie Hall; Robert Collins; Lynn Leffet; Karen Gallagher; Patricia Feldman; Paul Collier; Mark Stow; Xiaomei Gu; Frédéric Baribaud; Niu Shin; Beth Thomas; Timothy C Burn; Gregory F Hollis; Swamy Yeleswaram; Kimberley Solomon; Steve Friedman; Anlai Wang; Chu-Biao Xue; Robert C Newton; Peggy A Scherle; Kris Vaddi
Discovery and pharmacological characterization of a novel rodent-active CCR2 antagonist, INCB3344.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(8):5370-8.
2005: Bin-Bing S Zhou; Jordan S Fridman; Xiangdong Liu; Steven M Friedman; Robert C Newton; Peggy A Scherle
ADAM proteases, ErbB pathways and cancer.
Expert opinion on investigational drugs 2005;14(6):591-606.
2005: George V De Lucca; Ui Tae Kim; Brian J Vargo; John V Duncia; Joseph B Santella; Daniel S Gardner; Changsheng Zheng; Ann Y Liauw; Zhang Wang; George Emmett; Dean A Wacker; Patricia K Welch; Maryanne B Covington; Nicole C Stowell; Eric A Wadman; Anuk M Das; Paul Davies; Swamy Yeleswaram; Danielle Graden; Kimberly A Solomon; Robert C Newton; George L Trainor; Carl P Decicco; Soo S Ko
Discovery of CC chemokine receptor-3 (CCR3) antagonists with picomolar potency.
Journal of medicinal chemistry 2005;48(6):2194-211.
2004: Chu-Biao Xue; Xiao-Tao Chen; Xiaohua He; John Roderick; Ronald L Corbett; Bahman Ghavimi; Rui-Qin Liu; Maryanne B Covington; Mingxin Qian; Maria D Ribadeneira; Kris Vaddi; James M Trzaskos; Robert C Newton; James J-W Duan; Carl P Decicco
Synthesis and structure-activity relationship of a novel sulfone series of TNF-alpha converting enzyme inhibitors.
Bioorganic & medicinal chemistry letters 2004;14(17):4453-9.
2004: Dennis S Rice; Wenhu Huang; Holly A Jones; Gwenn Hansen; Gui-Lan Ye; Nianha Xu; Elizabeth A Wilson; Kathy Troughton; Kris Vaddi; Robert C Newton; Brian P Zambrowicz; Arthur T Sands
Severe retinal degeneration associated with disruption of semaphorin 4A.
Investigative ophthalmology & visual science 2004;45(8):2767-77.
2004: Robert J Cherney; Ruowei Mo; Dayton T Meyer; Karl D Hardman; Rui-Qin Liu; Maryanne B Covington; Mingxin Qian; Zelda R Wasserman; David D Christ; James M Trzaskos; Robert C Newton; Carl P Decicco
Sultam hydroxamates as novel matrix metalloproteinase inhibitors.
Journal of medicinal chemistry 2004;47(12):2981-3.
2004: Jeffrey G Varnes; Daniel S Gardner; Joseph B Santella; John V Duncia; Melissa Estrella; Paul S Watson; Cheryl M Clark; Soo S Ko; Patricia K Welch; Maryanne B Covington; Nicole C Stowell; Eric A Wadman; Paul Davies; Kimberley Solomon; Robert C Newton; George L Trainor; Carl P Decicco; Dean A Wacker
Discovery of N-propylurea 3-benzylpiperidines as selective CC chemokine receptor-3 (CCR3) antagonists.
Bioorganic & medicinal chemistry letters 2004;14(7):1645-9.
2003: Chu-Biao Xue; Xiaohua He; John Roderick; Ronald L Corbett; James J-W Duan; Rui-Qin Liu; Maryanne B Covington; Mingxin Qian; Maria D Ribadeneira; Kris Vaddi; David D Christ; Robert C Newton; James M Trzaskos; Ronald L Magolda; Ruth R Wexler; Carl P Decicco
Rational design, synthesis and structure-activity relationships of a cyclic succinate series of TNF-alpha converting enzyme inhibitors. Part 2: lead optimization.
Bioorganic & medicinal chemistry letters 2003;13(24):4299-304.
2003: Chu-Biao Xue; Xiaohua He; John Roderick; Ronald L Corbett; James J-W Duan; Rui-Qin Liu; Maryanne B Covington; Robert C Newton; James M Trzaskos; Ronald L Magolda; Ruth R Wexler; Carl P Decicco
Rational design, synthesis and structure-activity relationships of a cyclic succinate series of TNF-alpha converting enzyme inhibitors. Part 1: lead identification.
Bioorganic & medicinal chemistry letters 2003;13(24):4293-7.
2003: Michael A Pratta; Wenqing Yao; Carl P Decicco; Micky D Tortorella; Rui-Qin Liu; Robert Copeland; Ronald L Magolda; Robert C Newton; James M Trzaskos; Elizabeth C Arner
Aggrecan protects cartilage collagen from proteolytic cleavage.
The Journal of biological chemistry 2003;278(46):45539-45.
2003: James J-W Duan; Zhonghui Lu; Chu-Biao Xue; Xiaohua He; Jennifer L Seng; John Roderick; Zelda R Wasserman; Rui-Qin Liu; Maryanne B Covington; Ronald L Magolda; Robert C Newton; James M Trzaskos; Carl P Decicco
Discovery of N-hydroxy-2-(2-oxo-3-pyrrolidinyl)acetamides as potent and selective inhibitors of tumor necrosis factor-alpha converting enzyme (TACE).
Bioorganic & medicinal chemistry letters 2003;13(12):2035-40.
2003: Robert J Cherney; James J-W Duan; Matthew E Voss; Lihua Chen; Li Wang; Dayton T Meyer; Zelda R Wasserman; Karl D Hardman; Rui-Qin Liu; Maryanne B Covington; Mingxin Qian; Sandhya Mandlekar; David D Christ; James M Trzaskos; Robert C Newton; Ronald L Magolda; Ruth R Wexler; Carl P Decicco
Design, synthesis, and evaluation of benzothiadiazepine hydroxamates as selective tumor necrosis factor-alpha converting enzyme inhibitors.
Journal of medicinal chemistry 2003;46(10):1811-23.
2003: Robert J Cherney; Ruowei Mo; Dayton T Meyer; Li Wang; Wenqing Yao; Zelda R Wasserman; Rui-Qin Liu; Maryanne B Covington; Micky D Tortorella; Elizabeth C Arner; Mingxin Qian; David D Christ; James M Trzaskos; Robert C Newton; Ronald L Magolda; Carl P Decicco
Potent and selective aggrecanase inhibitors containing cyclic P1 substituents.
Bioorganic & medicinal chemistry letters 2003;13(7):1297-300.
2003: Michael A Pratta; Peggy A Scherle; Gengjie Yang; Rui-Qin Liu; Robert C Newton
Induction of aggrecanase 1 (ADAM-TS4) by interleukin-1 occurs through activation of constitutively produced protein.
Arthritis and rheumatism 2003;48(1):119-33.
2002: James J-W Duan; Lihua Chen; Zelda R Wasserman; Zhonghui Lu; Rui-Qin Liu; Maryanne B Covington; Mingxin Qian; Karl D Hardman; Ronald L Magolda; Robert C Newton; David D Christ; Ruth R Wexler; Carl P Decicco
Discovery of gamma-lactam hydroxamic acids as selective inhibitors of tumor necrosis factor alpha converting enzyme: design, synthesis, and structure-activity relationships.
Journal of medicinal chemistry 2002;45(23):4954-7.
2002: Micky D Tortorella; Rui-Qin Liu; Timothy C Burn; Robert C Newton; Elizabeth C Arner
Characterization of human aggrecanase 2 (ADAM-TS5): substrate specificity studies and comparison with aggrecanase 1 (ADAM-TS4).
Matrix biology : journal of the International Society for Matrix Biology 2002;21(6):499-511.
2002: George V De Lucca; Ui Tae Kim; Curt Johnson; Brian J Vargo; Patricia K Welch; Maryanne B Covington; Paul Davies; Kimberly A Solomon; Robert C Newton; George L Trainor; Carl P Decicco; Soo S Ko
Discovery and structure-activity relationship of N-(ureidoalkyl)-benzyl-piperidines as potent small molecule CC chemokine receptor-3 (CCR3) antagonists.
Journal of medicinal chemistry 2002;45(17):3794-804.
2002: Dean A Wacker; Joseph B Santella; Daniel S Gardner; Jeffrey G Varnes; Melissa Estrella; George V DeLucca; Soo S Ko; Keiichi Tanabe; Paul S Watson; Patricia K Welch; Maryanne B Covington; Nicole C Stowell; Eric A Wadman; Paul Davies; Kimberly A Solomon; Robert C Newton; George L Trainor; Steven M Friedman; Carl P Decicco; John V Duncia
CCR3 antagonists: a potential new therapy for the treatment of asthma. Discovery and structure-activity relationships.
Bioorganic & medicinal chemistry letters 2002;12(13):1785-9.
2001: Robert C Newton; Kimberly A Solomon; Maryanne B Covington; Carl P Decicco; P J Haley; Steven M Friedman; Kris Vaddi
Biology of TACE inhibition.
Annals of the rheumatic diseases 2001;60 Suppl 3():iii25-32.
2001: Chu-Biao Xue; Xiaohua He; Ronald L Corbett; John Roderick; Zelda R Wasserman; Rui-Qin Liu; BD Jaffee; Maryanne B Covington; Mingxin Qian; James M Trzaskos; Robert C Newton; Ronald L Magolda; Ruth R Wexler; Carl P Decicco
Discovery of macrocyclic hydroxamic acids containing biphenylmethyl derivatives at P1', a series of selective TNF-alpha converting enzyme inhibitors with potent cellular activity in the inhibition of TNF-alpha release.
Journal of medicinal chemistry 2001;44(21):3351-4.
2001: Percy H Carter; Peggy A Scherle; J K Muckelbauer; Matthew E Voss; Rui-Qin Liu; Lorin A Thompson; Andrew J Tebben; Kimberly A Solomon; Yvonne C Lo; Z Li; P Strzemienski; Gengjie Yang; N Falahatpisheh; M Xu; Z Wu; N A Farrow; Kalyanaraman Ramnarayan; J Wang; D Rideout; V Yalamoori; Peter J Domaille; D J Underwood; James M Trzaskos; Steven M Friedman; Robert C Newton; Carl P Decicco; J A Muckelbauer
Photochemically enhanced binding of small molecules to the tumor necrosis factor receptor-1 inhibits the binding of TNF-alpha.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(21):11879-84.
2001: Chu-Biao Xue; Matthew E Voss; David J Nelson; James J-W Duan; Robert J Cherney; Irina C Jacobson; Xiaohua He; John Roderick; Lihua Chen; Ronald L Corbett; Li Wang; Dayton T Meyer; K Kennedy; W F DeGradodagger; Karl D Hardman; Christopher A Teleha; BD Jaffee; Rui-Qin Liu; Robert Copeland; Maryanne B Covington; David D Christ; James M Trzaskos; Robert C Newton; Ronald L Magolda; Ruth R Wexler; Carl P Decicco
Design, synthesis, and structure-activity relationships of macrocyclic hydroxamic acids that inhibit tumor necrosis factor alpha release in vitro and in vivo.
Journal of medicinal chemistry 2001;44(16):2636-60.
1999: Kimberly A Solomon; N Pesti; G Wu; Robert C Newton
Cutting edge: a dominant negative form of TNF-alpha converting enzyme inhibits proTNF and TNFRII secretion.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(8):4105-8.
1999: I Abbaszade; Rui-Qin Liu; F Yang; SA Rosenfeld; OH Ross; John R Link; D M Ellis; Micky D Tortorella; Michael A Pratta; JM Hollis; Richard Wynn; JL Duke; Henry J George; Milton C Hillman; KATHLEEN MURPHY; BH Wiswall; Robert Copeland; Carl P Decicco; Robert Bruckner; H Nagase; Y Itoh; Robert C Newton; Ronald L Magolda; James M Trzaskos; Timothy C Burn
Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family.
The Journal of biological chemistry 1999;274(33):23443-50.
1999: Robert C Newton; Carl P Decicco
Therapeutic potential and strategies for inhibiting tumor necrosis factor-alpha.
Journal of medicinal chemistry 1999;42(13):2295-314.
1999: Elizabeth C Arner; Michael A Pratta; Carl P Decicco; Chu-Biao Xue; Robert C Newton; James M Trzaskos; Ronald L Magolda; Micky D Tortorella
Aggrecanase. A target for the design of inhibitors of cartilage degradation.
Annals of the New York Academy of Sciences 1999;878():92-107.
1999: Micky D Tortorella; Timothy C Burn; Michael A Pratta; I Abbaszade; JM Hollis; R Liu; SA Rosenfeld; Robert Copeland; Carl P Decicco; Richard Wynn; A Rockwell; F Yang; JL Duke; Kimberley Solomon; Henry J George; Robert Bruckner; H Nagase; Y Itoh; D M Ellis; H Ross; BH Wiswall; KATHLEEN MURPHY; Milton C Hillman; Gregory F Hollis; Robert C Newton; Ronald L Magolda; James M Trzaskos; Elizabeth C Arner
Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins.
Science (New York, N.Y.) 1999;284(5420):1664-6.
1997: Kimberly A Solomon; Maryanne B Covington; Carl P Decicco; Robert C Newton
The fate of pro-TNF-alpha following inhibition of metalloprotease-dependent processing to soluble TNF-alpha in human monocytes.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(9):4524-31.
1997: Robert C Newton; Kris Vaddi
Biological responses to C-C chemokines.
Methods in enzymology 1997;287():174-86.
1993: Douglas G Batt; R Goodman; D G Jones; Janet S Kerr; L R Mantegna; C McAllister; Robert C Newton; S Nurnberg; P K Welch; Maryanne B Covington
2'-substituted chalcone derivatives as inhibitors of interleukin-1 biosynthesis.
Journal of medicinal chemistry 1993;36(10):1434-42.
1992: Robert Horlick; Henry J George; G M Cooke; R J Tritch; Robert C Newton; A Dwivedi; M Lischwe; Francis Salemme; P C Weber; richard horuk
Permuteins of interleukin 1 beta--a simplified approach for the construction of permutated proteins having new termini.
Protein engineering 1992;5(5):427-31.
1987: Elizabeth C Arner; L R Darnell; Michael A Pratta; Robert C Newton; N R Ackerman; W Galbraith
Effect of antiinflammatory drugs on human interleukin-1-induced cartilage degradation.
Agents and actions 1987;21(3-4):334-6.