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Frans Belpaire

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TOP 3
Van Sassenbroeck Diederik K; De Neve Nikolaas; De Paepe Peter; Belpaire Frans M; Verstraete Alain G; Calle Paul A; Buylaert Walter A
Abrupt awakening phenomenon associated with gamma-hydroxybutyrate use: a case series.
Van Sassenbroeck Diederik K; Calle Paul A; Rousseau Filip M; Verstraete Alain G; Belpaire Frans M; Monsieurs Koenraad G; Haentjens Raoul; Allonsius Jacques; Van Brantegem Jean; Haenen Wim; Buylaert Walter A
Medical problems related to recreational drug use at nocturnal dance parties.
Lesaffer Gerrit; De Smet Rita; D'Heuvaert Tommy; Belpaire Frans M; Lameire Norbert; Vanholder Raymond
Comparative kinetics of the uremic toxin p-cresol versus creatinine in rats with and without renal failure.

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2007: Van Sassenbroeck Diederik K; De Neve Nikolaas; De Paepe Peter; Belpaire Frans M; Verstraete Alain G; Calle Paul A; Buylaert Walter A
Abrupt awakening phenomenon associated with gamma-hydroxybutyrate use: a case series.
Clinical toxicology (Philadelphia, Pa.) 2007;45(5):533-8.
2003: Van Sassenbroeck Diederik K; Calle Paul A; Rousseau Filip M; Verstraete Alain G; Belpaire Frans M; Monsieurs Koenraad G; Haentjens Raoul; Allonsius Jacques; Van Brantegem Jean; Haenen Wim; Buylaert Walter A
Medical problems related to recreational drug use at nocturnal dance parties.
European journal of emergency medicine : official journal of the European Society for Emergency Medicine 2003;10(4):302-8.
2003: Lesaffer Gerrit; De Smet Rita; D'Heuvaert Tommy; Belpaire Frans M; Lameire Norbert; Vanholder Raymond
Comparative kinetics of the uremic toxin p-cresol versus creatinine in rats with and without renal failure.
Kidney international 2003;64(4):1365-73.
2003: Lesaffer Gerrit; De Smet Rita; Belpaire Frans M; Van Vlem Bruno; Van Hulle Marijn; Cornelis Rita; Lameire Norbert; Vanholder Raymond
Urinary excretion of the uraemic toxin p-cresol in the rat: contribution of glucuronidation to its metabolization.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2003;18(7):1299-306.
2003: Van Sassenbroeck Diederik K; De Paepe Peter; Belpaire Frans M; Buylaert Walter A
Characterization of the pharmacokinetic and pharmacodynamic interaction between gamma-hydroxybutyrate and ethanol in the rat.
Toxicological sciences : an official journal of the Society of Toxicology 2003;73(2):270-8.
2003: Van Sassenbroeck Diederik K; De Paepe Peter; Belpaire Frans M; Boon Paul A; Buylaert Walter A
Tolerance to the hypnotic and electroencephalographic effect of gamma-hydroxybutyrate in the rat: pharmacokinetic and pharmacodynamic aspects.
The Journal of pharmacy and pharmacology 2003;55(5):609-15.
2003: De Paepe Peter; Belpaire Frans M; Van Hoey Gert; Boon Paul A; Buylaert Walter A
The influence of endotoxemia on the pharmacokinetics and the electroencephalographic effect of propofol in the rat.
Journal of pharmaceutical sciences 2003;92(1):104-14.
2002: Van Sassenbroeck Diederik K; De Paepe Peter; Belpaire Frans M; Boon Paul A; Buylaert Walter A
Influence of hypovolemia on the pharmacokinetics and electroencephalographic effect of gamma-hydroxybutyrate in the rat.
Anesthesiology 2002;97(5):1218-26.
2002: De Letter Els A; Belpaire Frans M; Clauwaert Karine M; Lambert Willy E; Van Bocxlaer Jan F; Piette Michel H A
Post-mortem redistribution of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") in the rabbit. Part II: post-mortem infusion in trachea or stomach.
International journal of legal medicine 2002;116(4):225-32.
2002: De Letter Els A; Clauwaert Karine M; Belpaire Frans M; Lambert Willy E; Van Bocxlaer Jan F; Piette Michel H A
Post-mortem redistribution of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") in the rabbit. Part I: experimental approach after in vivo intravenous infusion.
International journal of legal medicine 2002;116(4):216-24.
2002: Hemeryck Alex; Belpaire Frans M
Selective serotonin reuptake inhibitors and cytochrome P-450 mediated drug-drug interactions: an update.
Current drug metabolism 2002;3(1):13-37.
2002: De Paepe Peter; Belpaire Frans M; Buylaert Walter A
Pharmacokinetic and pharmacodynamic considerations when treating patients with sepsis and septic shock.
Clinical pharmacokinetics 2002;41(14):1135-51.
2001: Van Sassenbroeck D K; De Paepe P; Belpaire F M; Rosseel M T; Martens P; Boon P A; Buylaert W A
Relationship between gamma-hydroxybutyrate plasma concentrations and its electroencephalographic effects in the rat.
The Journal of pharmacy and pharmacology 2001;53(12):1687-96.
2001: De Paepe P; Van Sassenbroeck D K; Belpaire F M; Buylaert W A
Influence of naloxone on the increased sensitivity to propofol during hypovolemia in the rat.
Critical care medicine 2001;29(5):997-9.
2001: Hemeryck A; De Vriendt C A; Belpaire F M
Metoprolol-paroxetine interaction in human liver microsomes: stereoselective aspects and prediction of the in vivo interaction.
Drug metabolism and disposition: the biological fate of chemicals 2001;29(5):656-63.
2001: de Vriendt C A; van Sassenbroeck D K; Rosseel M T; van de Velde E J; Verstraete A G; Vander Heyden Y; Belpaire F M
Development and validation of a high-performance liquid chromatographic method for the determination of gamma-hydroxybutyric acid in rat plasma.
Journal of chromatography. B, Biomedical sciences and applications 2001;752(1):85-90.
2000: De Paepe P; Belpaire F M; Rosseel M T; Van Hoey G; Boon P A; Buylaert W A
Influence of hypovolemia on the pharmacokinetics and the electroencephalographic effect of propofol in the rat.
Anesthesiology 2000;93(6):1482-90.
2000: Hemeryck A; De Vriendt C; Belpaire F M
Effect of selective serotonin reuptake inhibitors on the oxidative metabolism of propafenone: in vitro studies using human liver microsomes.
Journal of clinical psychopharmacology 2000;20(4):428-34.
2000: Hemeryck A; Lefebvre R A; De Vriendt C; Belpaire F M
Paroxetine affects metoprolol pharmacokinetics and pharmacodynamics in healthy volunteers.
Clinical pharmacology and therapeutics 2000;67(3):283-91.
2000: De Letter E A; De Paepe P; Clauwaert K M; Belpaire F M; Lambert W E; Van Bocxlaer J F; Piette M H
Is vitreous humour useful for the interpretation of 3,4-methylenedioxymethamphetamine (MDMA) blood levels? Experimental approach with rabbits.
International journal of legal medicine 2000;114(1-2):29-35.
1999: Pan L; Belpaire F M
In vitro study on the involvement of CYP1A2, CYP2D6 and CYP3A4 in the metabolism of haloperidol and reduced haloperidol.
European journal of clinical pharmacology 1999;55(8):599-604.
1999: Pan L; Vander Stichele R; Rosseel M T; Berlo J A; De Schepper N; Belpaire F M
Effects of smoking, CYP2D6 genotype, and concomitant drug intake on the steady state plasma concentrations of haloperidol and reduced haloperidol in schizophrenic inpatients.
Therapeutic drug monitoring 1999;21(5):489-97.
1999: De Paepe P; Belpaire F M; Van Hoey G; Boon P A; Buylaert W A
Influence of hypovolemia on the pharmacokinetics and the electroencephalographic effect of etomidate in the rat.
The Journal of pharmacology and experimental therapeutics 1999;290(3):1048-53.
1999: De Paepe P; Van Hoey G; Belpaire F M; Rosseel M T; Boon P A; Buylaert W A
Relationship between etomidate plasma concentration and EEG effect in the rat.
Pharmaceutical research 1999;16(6):924-9.
1999: Hemeryck A; De Vriendt C; Belpaire F M
Inhibition of CYP2C9 by selective serotonin reuptake inhibitors: in vitro studies with tolbutamide and (S)-warfarin using human liver microsomes.
European journal of clinical pharmacology 1999;54(12):947-51.
1998: Pan L P; De Vriendt C; Belpaire F M
In-vitro characterization of the cytochrome P450 isoenzymes involved in the back oxidation and N-dealkylation of reduced haloperidol.
Pharmacogenetics 1998;8(5):383-9.
1998: Belpaire F M; Wijnant P; Temmerman A; Rasmussen B B; Brøsen K
The oxidative metabolism of metoprolol in human liver microsomes: inhibition by the selective serotonin reuptake inhibitors.
European journal of clinical pharmacology 1998;54(3):261-4.
1998: Pan L; Rosseel M T; Belpaire F M
Comparison of two high-performance liquid chromatographic methods for monitoring plasma concentrations of haloperidol and reduced haloperidol.
Therapeutic drug monitoring 1998;20(2):224-30.
1998: Vermeire A; Remon J P; Rosseel M T; Belpaire F; Devulder J; Bogaert M G
Variability of morphine disposition during long-term subcutaneous infusion in terminally ill cancer patients.
European journal of clinical pharmacology 1998;53(5):325-30.
1998: Verstraete A G; Belpaire F M; Leroux-Roels G G
Diagnostic performance of the EMIT-tox benzodiazepine immunoassay, FPIA serum benzodiazepine immunoassay, and radioreceptor assay in suspected acute poisoning.
Journal of analytical toxicology 1998;22(1):27-32.
1998: De Paepe P; Belpaire F M; Rosseel M T; Buylaert W A
The influence of hemorrhagic shock on the pharmacokinetics and the analgesic effect of morphine in the rat.
Fundamental & clinical pharmacology 1998;12(6):624-30.
1998: Fonck K; Haenebalcke C; Hemeryck A; Belpaire F; Jordaens L; Calle P; Buylaert W
ECG changes and plasma concentrations of propafenone and its metabolites in a case of severe poisoning.
Journal of toxicology. Clinical toxicology 1998;36(3):247-51.
1997: Pan L P; Wijnant P; De Vriendt C; Rosseel M T; Belpaire F M
Characterization of the cytochrome P450 isoenzymes involved in the in vitro N-dealkylation of haloperidol.
British journal of clinical pharmacology 1997;44(6):557-64.
1996: Bartoletti R A; Belpaire F M; Rosseel M T
High performance liquid chromatography determination of dextromethorphan and its metabolites in urine using solid-phase extraction.
Journal of pharmaceutical and biomedical analysis 1996;14(8-10):1281-86.
1996: Laethem M E; Belpaire F M; Bogaert M G
Direct high-performance liquid chromatography determination of diastereomeric oxprenolol glucuronides.
Journal of chromatography. B, Biomedical applications 1996;675(2):251-5.
1996: Belpaire F M; Bogaert M G
Cytochrome P450: genetic polymorphism and drug interactions.
Acta clinica Belgica 1996;51(4):254-60.
1995: Laethem M E; Belpaire F M; Wijnant P; Bogaert M G
Effect of probenecid on the enantioselective pharmacokinetics of oxprenolol and its glucuronides in the rabbit.
Pharmaceutical research 1995;12(12):1964-7.
1995: Laethem M E; Lefebvre R A; Belpaire F M; Vanhoe H L; Bogaert M G
Stereoselective pharmacokinetics of oxprenolol and its glucuronides in humans.
Clinical pharmacology and therapeutics 1995;57(4):419-24.
1995: Belpaire F M; Wynant P; Van Trappen P; Dhont M; Verstraete A; Bogaert M G
Protein binding of propranolol and verapamil enantiomers in maternal and foetal serum.
British journal of clinical pharmacology 1995;39(2):190-3.
1995: Laethem M E; Belpaire F M; Wijnant P; Bogaert M G
Stereoselective pharmacokinetics of oxprenolol, propranolol, and verapamil: species differences and influence of endotoxin.
Chirality 1995;7(8):616-22.
1994: Van den Bulcke M; Rosseel M T; Wijnants P; Buylaert W; Belpaire F M
Metabolism and hepatotoxicity of N,N-dimethylformamide, N-hydroxymethyl-N-methylformamide, and N-methylformamide in the rat.
Archives of toxicology 1994;68(5):291-5.
1994: Laethem M E; Belpaire F M; Wijnant P; Rosseel M T; Bogaert M G
Influence of endotoxin on the stereoselective pharmacokinetics of oxprenolol, propranolol, and verapamil in the rat.
Chirality 1994;6(5):405-10.
1994: Vercruysse I; Vermeulen A M; Belpaire F M; Massart D L; Dupont A G
The effect of different calcium antagonists and a calcium agonist on the metabolism of propranolol by isolated rat hepatocytes.
Fundamental & clinical pharmacology 1994;8(4):373-8.
1993: Laethem M E; Rosseel M T; Wijnant P; Belpaire F M
Chiral high-performance liquid chromatographic determination of oxprenolol in plasma.
Journal of chromatography 1993;621(2):225-9.
1993: Vermeulen A M; Belpaire F M; De Smet F; Vercruysse I; Bogaert M G
Aging and the pharmacokinetics and metabolism of metoprolol enantiomers in the rat.
Journal of gerontology 1993;48(3):B108-14.
1993: Rosseel M T; Belpaire F M; Samijn N; Wijnant P
Simultaneous determination of N,N-dimethylformamide, N-monomethylformamide and N-hydroxymethyl-N-methylformamide in rat plasma by capillary gas chromatography.
Journal of chromatography 1993;615(1):154-8.
1993: Belpaire F M; Rosseel M T; Vermeulen A M; De Smet F; Bogaert M G
Stereoselective pharmacokinetics of atenolol in the rat: influence of aging and of renal failure.
Mechanisms of ageing and development 1993;67(1-2):201-10.
1993: Vermeulen A M; Belpaire F M; de Smet F; Bogaert M G
Influence of human recombinant interleukin-1 beta on the enantioselective disposition of propranolol in rats.
Biochemical pharmacology 1993;45(1):1-6.
1992: Vermeulen A M; Belpaire F M; De Smet F; Rosseel M T; Bogaert M G
Influence of age on stereoselective pharmacokinetics and metabolism of hexobarbital in the rat.
Mechanisms of ageing and development 1992;65(2-3):167-75.
1992: Vermeulen A M; Belpaire F M; Moerman E; de Smet F; Bogaert M G
The influence of aging on the stereoselective pharmacokinetics of propranolol in the rat.
Chirality 1992;4(2):73-9.
1992: Willems J L; Langenberg J P; Verstraete A G; De Loose M; Vanhaesebroeck B; Goethals G; Belpaire F M; Buylaert W A; Vogelaers D; Colardyn F
Plasma concentrations of pralidoxime methylsulphate in organophosphorus poisoned patients.
Archives of toxicology 1992;66(4):260-6.
1991: Vermeulen A M; Belpaire F M; De Smet F; Bogaert M G
The enantiomeric distribution of propranolol is not influenced by its beta-blocking activity.
The Journal of pharmacy and pharmacology 1991;43(9):671-2.
1991: Vermeulen A M; Rosseel M T; Belpaire F M
High-performance liquid chromatographic method for the simultaneous determination of R-(-)- and S-(+)-hexobarbital in rat plasma.
Journal of chromatography 1991;567(2):472-9.
1991: Rosseel M T; Vermeulen A M; Belpaire F M
Reversed-phase high-performance liquid chromatographic analysis of atenolol enantiomers in plasma after chiral derivatization with (+)-1-(9-fluorenyl)ethyl chloroformate.
Journal of chromatography 1991;568(1):239-45.
1991: Belpaire F M; Bogaert M G
Binding of alfentanil to human alpha 1-acid glycoprotein, albumin and serum.
International journal of clinical pharmacology, therapy, and toxicology 1991;29(3):96-102.
1990: Belpaire F M; de Smet F; Vynckier L J; Vermeulen A M; Rosseel M T; Bogaert M G; Chauvelot-Moachon L
Effect of aging on the pharmcokinetics of atenolol, metoprolol and propranolol in the rat.
The Journal of pharmacology and experimental therapeutics 1990;254(1):116-22.
1990: Belpaire F M; Bogaert M G
Binding of diltiazem to albumin, alpha 1-acid glycoprotein and to serum in man.
Journal of clinical pharmacology 1990;30(4):311-7.
1990: Belpaire F M; De Rick A; Bourda A; De Smet F; Rosseel M T; Bogaert M G
Influence of lignocaine on plasma protein binding and pharmacokinetics of verapamil in dogs.
The Journal of pharmacy and pharmacology 1990;42(1):45-9.
1989: Fraeyman N H; Van de Velde E J; Belpaire F M; Lameire N H
Glycan microheterogeneity of alpha 1-acid glycoprotein in sera and dialysates of patients on continuous ambulatory peritoneal dialysis.
Clinica chimica acta; international journal of clinical chemistry 1989;181(1):47-54.
1989: Belpaire F M; De Rick A; De Smet F; Bourda A; Rosseel M T; Bogaert M G
Influence of lidocaine on plasma protein binding and pharmacokinetics of verapamil in dogs.
Progress in clinical and biological research 1989;300():437-40.
1989: Belpaire F M; de Smet F; Chindavijak B; Fraeyman N; Bogaert M G
Effect of turpentine-induced inflammation on the disposition kinetics of propranolol, metoprolol, and antipyrine in the rat.
Fundamental & clinical pharmacology 1989;3(2):79-88.
1989: Belpaire F M; Bogaert M G
Pharmacokinetic and pharmacodynamic consequences of altered binding of drugs to alpha 1-acid glycoprotein.
Progress in clinical and biological research 1989;300():337-50.
1988: Chindavijak B; Belpaire F M; De Smet F; Bogaert M G
Alteration of the pharmacokinetics and metabolism of propranolol and antipyrine elicited by indwelling catheters in the rat.
The Journal of pharmacology and experimental therapeutics 1988;246(3):1075-9.
1988: Lefebvre R A; Belpaire F M; Bogaert M G
Influence of food on steady state serum concentrations of theophylline from two controlled-release preparations.
International journal of clinical pharmacology, therapy, and toxicology 1988;26(8):375-9.
1988: Fraeyman N F; Dello C D; Belpaire F M
Alpha 1-acid glycoprotein concentration and molecular heterogeneity: relationship to oxprenolol binding in serum from healthy volunteers and patients with lung carcinoma or cirrhosis.
British journal of clinical pharmacology 1988;25(6):733-40.
1988: Dello C P; Belpaire F M; De Rick A; Fraeyman N H
Influence of inflammation on serum concentration, molecular heterogeneity and drug binding properties of canine alpha-1-acid glycoprotein.
Journal of veterinary pharmacology and therapeutics 1988;11(1):71-6.
1988: Chindavijak B; Belpaire F M; Bogaert M G
Effect of inflammation on the metabolism of antipyrine, lidocaine and propranolol in isolated rat hepatocytes.
Pharmacology 1988;36(4):279-82.
1988: Belpaire F M; Van de Velde E J; Fraeyman N H; Bogaert M G; Lameire N
Influence of continuous ambulatory peritoneal dialysis on serum alpha 1-acid glycoprotein concentration and drug binding.
European journal of clinical pharmacology 1988;35(4):339-43.
1987: Dello C P; Belpaire F M; Kint J A; Fraeyman N H
Dog alpha-1-acid glycoprotein: purification and biochemical characterization.
Journal of pharmacological methods 1987;18(4):335-45.
1987: Chindavijak B; Belpaire F M; Bogaert M G
Effect of inflammation and proadifen on the disposition of antipyrine, lignocaine and propranolol in rat isolated perfused liver.
The Journal of pharmacy and pharmacology 1987;39(12):997-1002.
1987: Chindavijak B; Belpaire F M; Bogaert M G
In-vitro biotransformation of antipyrine, lignocaine and propranolol in the liver of rats with turpentine-induced inflammation.
The Journal of pharmacy and pharmacology 1987;39(11):883-6.
1987: De Rick A F; Belpaire F M; Dello C; Bogaert M G
Influence of enhanced alpha-1-acid glycoprotein concentration on protein binding, pharmacokinetics and antiarrhythmic effect of lidocaine in the dog.
The Journal of pharmacology and experimental therapeutics 1987;241(1):289-93.
1987: Belpaire F M; De Rick A; Dello C; Fraeyman N; Bogaert M G
Alpha 1-acid glycoprotein and serum binding of drugs in healthy and diseased dogs.
Journal of veterinary pharmacology and therapeutics 1987;10(1):43-8.
1987: Belpaire F M; Chindavijak B; Bogaert M G
SKF 525A displaces drugs from serum alpha 1-acid glycoprotein binding sites.
The Journal of pharmacology and experimental therapeutics 1987;240(2):628-30.
1983: Belpaire F M; Rosseel M T; Bogaert M G; De Rick A; D'Heer F
Enhanced serum binding of propranolol and oxprenolol and microsomal enzyme induction by rifampicin in the dog.
Biochemical pharmacology 1983;32(6):1122-5.
1982: Belpaire F M; Rosseel M T; De Rick A
Enhanced plasma binding of propranolol and oxprenolol and induction of hexobarbital and antipyrine metabolism by rifampicin treatment in the dog.
Archives internationales de pharmacodynamie et de thérapie 1982;259(2):303-4.

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Frans Belpaire

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