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Dominic Ng

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Dominic S Ng; Norman C W Wong; Robert A Hegele
HDL-is it too big to fail?
Lauren Hager; Mohammad A Hossain; Lixin Li; Lu Liu; Lilia Magomedova; Graham F Maguire; Mark Naples; Khosrow Adeli; Chris Baker; Philip W Connelly; Carolyn L Cummins; Henry Pun; Jonathan Tam; Dominic S Ng
Lecithin:cholesterol acyltransferase deficiency protects against cholesterol-induced hepatic endoplasmic reticulum stress in mice.
L Li; L Liu; T Jin; L Tam; Dominic S Ng
Wnt-signaling mediates the anti-adipogenic action of lysophosphatidic acid through cross talking with the Rho/Rho associated kinase (ROCK) pathway.

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All Publications

2013: Dominic S Ng; Norman C W Wong; Robert A Hegele
HDL-is it too big to fail?
Nature reviews. Endocrinology 2013;9(5):308-12.
2012: Lauren Hager; Mohammad A Hossain; Lixin Li; Lu Liu; Lilia Magomedova; Graham F Maguire; Mark Naples; Khosrow Adeli; Chris Baker; Philip W Connelly; Carolyn L Cummins; Henry Pun; Jonathan Tam; Dominic S Ng
Lecithin:cholesterol acyltransferase deficiency protects against cholesterol-induced hepatic endoplasmic reticulum stress in mice.
The Journal of biological chemistry 2012;287(24):20755-68.
2011: L Li; L Liu; T Jin; L Tam; Dominic S Ng
Wnt-signaling mediates the anti-adipogenic action of lysophosphatidic acid through cross talking with the Rho/Rho associated kinase (ROCK) pathway.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2011;89(6):515-21.
2011: Lixin Li; Mohammad A Hossain; Sabreena Sadat; Lauren Hager; Lu Liu; Laetitia Tam; Stephanie Schroer; Lu Huogen; I George Fantus; Philip W Connelly; Minna Woo; Dominic S Ng
Lecithin cholesterol acyltransferase null mice are protected from diet-induced obesity and insulin resistance in a gender-specific manner through multiple pathways.
The Journal of biological chemistry 2011;286(20):17809-20.
2008: Dominic S Ng; Tina Chu; Bruno Esposito; Patrick Hui; Philip W Connelly; Peter L Gross
Paraoxonase-1 deficiency in mice predisposes to vascular inflammation, oxidative stress, and thrombogenicity in the absence of hyperlipidemia.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 2008;17(4):226-32.
2007: Lixin Li; Mark Naples; Hui Song; Ronghua Yuan; Feilu Ye; Sharmi Shafi; Khosrow Adeli; Dominic S Ng
LCAT-null mice develop improved hepatic insulin sensitivity through altered regulation of transcription factors and suppressors of cytokine signaling.
American journal of physiology. Endocrinology and metabolism 2007;293(2):E587-94.
2006: Hui Song; Liping Zhu; Clive M Picardo; Graham Maguire; Vincent Leung; Philip W Connelly; Dominic S Ng
Coordinated alteration of hepatic gene expression in fatty acid and triglyceride synthesis in LCAT-null mice is associated with altered PUFA metabolism.
American journal of physiology. Endocrinology and metabolism 2006;290(1):E17-E25.
2004: Dominic S Ng
Insight into the role of LCAT from mouse models.
Reviews in endocrine & metabolic disorders 2004;5(4):311-8.
2004: Xianghong Zhu; Andrew Herzenberg; Mohammad Eskandarian; Graham F Maguire; James W Scholey; Philip W Connelly; Dominic S Ng
A novel in vivo lecithin-cholesterol acyltransferase (LCAT)-deficient mouse expressing predominantly LpX is associated with spontaneous glomerulopathy.
The American journal of pathology 2004;165(4):1269-78.
2004: Dominic S Ng
Treating low HDL--from bench to bedside.
Clinical biochemistry 2004;37(8):649-59.
2004: Dominic S Ng; Chunhui Xie; Graham F Maguire; Xianghong Zhu; Francisca Ugwu; Eric Lam; Philip W Connelly
Hypertriglyceridemia in lecithin-cholesterol acyltransferase-deficient mice is associated with hepatic overproduction of triglycerides, increased lipogenesis, and improved glucose tolerance.
The Journal of biological chemistry 2004;279(9):7636-42.
2002: Dominic S Ng; Graham F Maguire; John Wylie; Amir Ravandi; Wanli Xuan; Zakaria Ahmed; Mohammad Eskandarian; Arnis Kuksis; Philip W Connelly
Oxidative stress is markedly elevated in lecithin:cholesterol acyltransferase-deficient mice and is paradoxically reversed in the apolipoprotein E knockout background in association with a reduction in atherosclerosis.
The Journal of biological chemistry 2002;277(14):11715-20.