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Leong Ng

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TOP 3
P P Jani; H Narayan; Leong L Ng
The differential extraction and immunoluminometric assay of Urotensin II and Urotensin-related peptide in heart failure.
Hazim Rahbi; Donald J L Jones; Hafid Narayan; Leong L Ng
The uroguanylin system and human disease.
Paul A Scott; Mehmood Zeb; Bashar Zeidan; Nick P Curzen; Spiros Garbis; John M Morgan; Leong L Ng; James A Rosengarten; Paul A Townsend
Proteomic profiling to identify prognostic biomarkers in heart failure.

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All Publications

2013: P P Jani; H Narayan; Leong L Ng
The differential extraction and immunoluminometric assay of Urotensin II and Urotensin-related peptide in heart failure.
Peptides 2013;40():72-6.
2012: Hazim Rahbi; Donald J L Jones; Hafid Narayan; Leong L Ng
The uroguanylin system and human disease.
Clinical science (London, England : 1979) 2012;123(12):659-68.
2012: Paul A Scott; Mehmood Zeb; Bashar Zeidan; Nick P Curzen; Spiros Garbis; John M Morgan; Leong L Ng; James A Rosengarten; Paul A Townsend
Proteomic profiling to identify prognostic biomarkers in heart failure.
In vivo (Athens, Greece) 2012;26(6):875-82.
2012: Robin A P Weir; Suzanne Clements; Henry J Dargie; Iain B McInnes; Ashley M Miller; Leong L Ng; Colin J Petrie; Iain B Squire; Tracey Steedman; John J V McMurray
Interleukin-21--a biomarker of importance in predicting myocardial function following acute infarction?
Cytokine 2012;60(1):220-5.
2012: Benjamin D Hunt; Leong L Ng; David G Lambert
In vitro siRNA-mediated knockdown of the UT receptor: implications of density on the efficacy of a range of UT ligands.
Naunyn-Schmiedeberg's archives of pharmacology 2012;385(6):651-6.
2012: Yvan Devaux; Etienne Gayat; Dominic Kelly; Marie-Lise Lair; Johan Lassus; Leong L Ng; Michel Vaillant; Melanie Vausort; Daniel R Wagner; Francisco Azuaje; Iain B Squire
Low levels of vascular endothelial growth factor B predict left ventricular remodeling after acute myocardial infarction.
Journal of cardiac failure 2012;18(4):330-7.
2012: Alan Maisel; James McCord; Martin Möckel; Nils G. Morgenthaler; Christian Mueller; Sean-Xavier Neath; Leong L Ng; Richard M Nowak; W Frank Peacock; Piotr Ponikowski; Mihael Potocki; Mark Richards; Garret Terracciano; Alan H B Wu; Andreas Bergmann; Robert H Christenson; Paul Clopton; Lori B Daniels; Salvatore Di Somma; Gerasimos S Filippatos; Oliver Hartmann; Christopher Hogan; Judd Landsberg; Inder Anand; Stefan D Anker
Use of procalcitonin for the diagnosis of pneumonia in patients presenting with a chief complaint of dyspnoea: results from the BACH (Biomarkers in Acute Heart Failure) trial.
European journal of heart failure 2012;14(3):278-86.
2012: Christopher D Steadman; Benjamin Grundy; Michael Jerosch-Herold; Leong L Ng; Suzanne Rafelt; Nilesh J Samani; Iain B Squire; Gerry P McCann
Determinants and functional significance of myocardial perfusion reserve in severe aortic stenosis.
JACC. Cardiovascular imaging 2012;5(2):182-9.
2011: Paul A Scott; Paul A Townsend; Mehmood Zeb; Nick P Curzen; Scott Harris; Leong L Ng; Paul J Roderick; John M Morgan
Defining potential to benefit from implantable cardioverter defibrillator therapy: the role of biomarkers.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2011;13(10):1419-27.
2011: W Frank Peacock; Piotr Ponikowski; Mark Richards; Alan H B Wu; Martin Möckel; Nils Morgenthaler; Christian Mueller; Sean Xavier Neath; Leong L Ng; Richard M Nowak; Inder Anand; Stefan D Anker; Robert H Christenson; Lori B Daniels; Salvatore DiSomma; Gerasimos S Filippatos; Oliver Hartmann; Christopher Hogan; Alan S Maisel
Short-term mortality risk in emergency department acute heart failure.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2011;18(9):947-58.
2011: Alan Maisel; James McCord; Martin Mockel; Nils G. Morgenthaler; Christian Mueller; Sean-Xavier Neath; Leong L Ng; Richard M Nowak; W Frank Peacock; Piotr Ponikowski; Mihael Potocki; Mark Richards; Alan H B Wu; Robert H Christenson; Paul Clopton; Lori B Daniels; Salvatore Di Somma; Gerasimos S Filippatos; Oliver Hartmann; Christopher Hogan; Inder Anand; Stefan D Anker
Midregion prohormone adrenomedullin and prognosis in patients presenting with acute dyspnea: results from the BACH (Biomarkers in Acute Heart Failure) trial.
Journal of the American College of Cardiology 2011;58(10):1057-67.
2011: Hafid Narayan; Onkar S Dhillon; Pauline A Quinn; Joachim Struck; Iain B Squire; Joan E Davies; Leong L Ng
C-terminal provasopressin (copeptin) as a prognostic marker after acute non-ST elevation myocardial infarction: Leicester Acute Myocardial Infarction Peptide II (LAMP II) study.
Clinical science (London, England : 1979) 2011;121(2):79-89.
2011: Onkar S Dhillon; Hafid K Narayan; Paulene A Quinn; Iain B Squire; Joan E Davies; Leong L Ng
Interleukin 33 and ST2 in non-ST-elevation myocardial infarction: comparison with Global Registry of Acute Coronary Events Risk Scoring and NT-proBNP.
American heart journal 2011;161(6):1163-70.
2011: Robin A P Weir; Suzanne Clements; Tracey Steedman; Henry J Dargie; John J V McMurray; Iain B Squire; Leong L Ng
Plasma TIMP-4 predicts left ventricular remodeling after acute myocardial infarction.
Journal of cardiac failure 2011;17(6):465-71.
2011: Sanjay S Bhandari; Joan E Davies; Joachim Struck; Leong L Ng
Influence of confounding factors on plasma mid-regional pro-adrenomedullin and mid-regional pro-A-type natriuretic peptide concentrations in healthy individuals.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2011;16(3):281-7.
2011: Leong L Ng; Sohail Q Khan; Hafid Narayan; Paulene Quinn; Iain B Squire; Joan E Davies
Proteinase 3 and prognosis of patients with acute myocardial infarction.
Clinical science (London, England : 1979) 2011;120(6):231-8.
2010: Dominic Kelly; Iain B Squire; Sohail Q Khan; Onkar Dhillon; Hafid Narayan; K H Ng; Paulene Quinn; Joan E Davies; Leong L Ng
Usefulness of plasma tissue inhibitors of metalloproteinases as markers of prognosis after acute myocardial infarction.
The American journal of cardiology 2010;106(4):477-82.
2010: Onkar S Dhillon; Sohail Q Khan; Hafid K Narayan; Kelvin H Ng; Joachim Struck; Paulene A Quinn; Nils G. Morgenthaler; Iain B Squire; Joan E Davies; Andreas Bergmann; Leong L Ng
Prognostic value of mid-regional pro-adrenomedullin levels taken on admission and discharge in non-ST-elevation myocardial infarction: the LAMP (Leicester Acute Myocardial Infarction Peptide) II study.
Journal of the American College of Cardiology 2010;56(2):125-33.
2010: Sanjay Gupta; Carolyn Waywell; Nandkumar Gandhi; Nigel Clayton; Brian G Keevil; Andrew L Clark; Leong L Ng; Nicholas Brooks; Ludwig Neyses
The effects of adding torasemide to standard therapy on peak oxygen consumption, natriuretic peptides, and quality of life in patients with compensated left ventricular systolic dysfunction.
European journal of heart failure 2010;12(7):746-52.
2010: Benjamin D Hunt; Leong L Ng; David G Lambert
A rat brain atlas of urotensin-II receptor expression and a review of central urotensin-II effects.
Naunyn-Schmiedeberg's archives of pharmacology 2010;382(1):1-31.
2010: Dominic Kelly; Sohail Q Khan; Onkar Dhillon; Paulene Quinn; Joachim Struck; Iain B Squire; Joan E Davies; Leong L Ng
Procalcitonin as a prognostic marker in patients with acute myocardial infarction.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2010;15(4):325-31.
2010: Christopher D Steadman; Simon Ray; Leong L Ng; Gerry P McCann
Natriuretic peptides in common valvular heart disease.
Journal of the American College of Cardiology 2010;55(19):2034-48.
2010: Robin A P Weir; Sean Balmain; Tracey Steedman; Leong L Ng; Iain B Squire; Anne Rumley; Henry J Dargie; Gordon D O Lowe
Tissue plasminogen activator antigen predicts medium-term left ventricular end-systolic volume after acute myocardial infarction.
Journal of thrombosis and thrombolysis 2010;29(4):421-8.
2010: Ian B Squire; Kent L Woods; David R Jones; Christopher P Nelson; Leong L Ng; Paul C Lambert
Prognostic value of admission blood glucose concentration and diabetes diagnosis on survival after acute myocardial infarction: results from 4702 index cases in routine practice.
Clinical science (London, England : 1979) 2010;118(8):527-35.
2010: Hafid Narayan; Noor Mohammed; Paulene A Quinn; Iain B Squire; Joan E Davies; Leong L Ng
Activation of a novel natriuretic endocrine system in humans with heart failure.
Clinical science (London, England : 1979) 2010;118(5):367-74.
2010: Onkar S Dhillon; Sohail Q Khan; Hafid K Narayan; Kelvin H Ng; Noor Mohammed; Paulene A Quinn; Iain B Squire; Joan E Davies; Leong L Ng
Matrix metalloproteinase-2 predicts mortality in patients with acute coronary syndrome.
Clinical science (London, England : 1979) 2010;118(4):249-57.
2010: Daniel Chan; Leong L Ng
Biomarkers in acute myocardial infarction.
BMC medicine 2010;8():34.
2010: Sanjay S Bhandari; Joan E Davies; Joachim Struck; Leong L Ng
The midregional portion of proadrenomedullin is an independent predictor of left ventricular mass index in hypertension.
Metabolism: clinical and experimental 2010;59(1):7-13.
2009: Madura S Batuwangala; Girolamo Calo; Remo Guerrini; Leong L Ng; John McDonald; David G Lambert
Desensitisation of native and recombinant human urotensin-II receptors.
Naunyn-Schmiedeberg's archives of pharmacology 2009;380(5):451-7.
2009: Paul W X Foley; Berthold Stegemann; Kelvin Ng; Sud Ramachandran; Anthony Proudler; Michael P Frenneaux; Leong L Ng; Francisco Leyva
Growth differentiation factor-15 predicts mortality and morbidity after cardiac resynchronization therapy.
European heart journal 2009;30(22):2749-57.
2009: Sohail Q Khan; Hafid Narayan; Kelvin H Ng; Onkar S Dhillon; Dominic Kelly; Paulene Quinn; Iain B Squire; Joan E Davies; Leong L Ng
N-terminal pro-B-type natriuretic peptide complements the GRACE risk score in predicting early and late mortality following acute coronary syndrome.
Clinical science (London, England : 1979) 2009;117(1):31-9.
2009: Robin A P Weir; Patrick B Mark; Colin J Petrie; Suzanne Clements; Tracey Steedman; Ian Ford; Leong L Ng; Iain B Squire; Galen S Wagner; John J V McMurray; Henry J Dargie
Left ventricular remodeling after acute myocardial infarction: does eplerenone have an effect?
American heart journal 2009;157(6):1088-96.
2009: Madura Batuwangala; Valeria Camarda; John McDonald; Erika Marzola; David G Lambert; Leong L Ng; Girolamo Calo'; Domenico Regoli; Claudio Trapella; Remo Guerrini; Severo Salvadori
Structure-activity relationship study on Tyr9 of urotensin-II(4-11): identification of a partial agonist of the UT receptor.
Peptides 2009;30(6):1130-6.
2009: Sohail Q Khan; Kelvin Ng; Onkar Dhillon; Dominic Kelly; Paulene Quinn; Iain B Squire; Joan E Davies; Leong L Ng
Growth differentiation factor-15 as a prognostic marker in patients with acute myocardial infarction.
European heart journal 2009;30(9):1057-65.
2009: Sanjay S Bhandari; Ian Loke; Joan E Davies; Iain B Squire; Joachim Struck; Leong L Ng
Gender and renal function influence plasma levels of copeptin in healthy individuals.
Clinical science (London, England : 1979) 2009;116(3):257-63.
2008: Dominic Kelly; Iain B Squire; Sohail Q Khan; Paulene Quinn; Joachim Struck; Nils G. Morgenthaler; Joan E Davies; Leong L Ng
C-terminal provasopressin (copeptin) is associated with left ventricular dysfunction, remodeling, and clinical heart failure in survivors of myocardial infarction.
Journal of cardiac failure 2008;14(9):739-45.
2008: Dominic Kelly; Sohail Q Khan; Matt Thompson; Gillian W Cockerill; Leong L Ng; Nilesh Samani; Iain B Squire
Plasma tissue inhibitor of metalloproteinase-1 and matrix metalloproteinase-9: novel indicators of left ventricular remodelling and prognosis after acute myocardial infarction.
European heart journal 2008;29(17):2116-24.
2008: Sohail Q Khan; Onkar Dhillon; Dominic Kelly; Iain B Squire; Joachim Struck; Paulene Quinn; Nils G. Morgenthaler; Andreas Bergmann; Joan E Davies; Leong L Ng
Plasma N-terminal B-Type natriuretic peptide as an indicator of long-term survival after acute myocardial infarction: comparison with plasma midregional pro-atrial natriuretic peptide: the LAMP (Leicester Acute Myocardial Infarction Peptide) study.
Journal of the American College of Cardiology 2008;51(19):1857-64.
2008: D Kelly; S Khan; Gillian W Cockerill; Leong L Ng; M Thompson; Nilesh J Samani; Iain B Squire
Circulating stromelysin-1 (MMP-3): a novel predictor of LV dysfunction, remodelling and all-cause mortality after acute myocardial infarction.
European journal of heart failure 2008;10(2):133-9.
2008: Sohail Q Khan; Paulene Quinn; Joan E Davies; Leong L Ng
N-terminal pro-B-type natriuretic peptide is better than TIMI risk score at predicting death after acute myocardial infarction.
Heart (British Cardiac Society) 2008;94(1):40-3.
2007: Sohail Q Khan; Onkar Dhillon; Joachim Struck; Paulene Quinn; Nils G. Morgenthaler; Iain B Squire; Joan E Davies; Andreas Bergmann; Leong L Ng
C-terminal pro-endothelin-1 offers additional prognostic information in patients after acute myocardial infarction: Leicester Acute Myocardial Infarction Peptide (LAMP) Study.
American heart journal 2007;154(4):736-42.
2007: Donald J L Jones; Richard Willingale; Paulene A Quinn; John H Lamb; Peter B Farmer; Joan E Davies; Leong L Ng
Improving the diagnostic accuracy of N-terminal B-type natriuretic peptide in human systolic heart failure by plasma profiling using mass spectrometry.
Journal of proteome research 2007;6(8):3329-34.
2007: D Dean Potter; Philip A Araoz; Leong L Ng; David G Kruger; Jess L Thompson; Chad E Hamner; Joseph A Rysavy; Jayawant N Mandrekar; Thoralf M Sundt
Cardiotropin-1 and myocardial strain change heterogeneously in cardiomyopathy.
The Journal of surgical research 2007;141(2):277-83.
2007: Sohail Q Khan; Dominic Kelly; Paulene Quinn; Joan E Davies; Leong L Ng
Myeloperoxidase aids prognostication together with N-terminal pro-B-type natriuretic peptide in high-risk patients with acute ST elevation myocardial infarction.
Heart (British Cardiac Society) 2007;93(7):826-31.
2007: Leong L Ng; Russell J O'brien; Paulene A Quinn; Iain B Squire; Joan E Davies
Oxygen-regulated protein 150 and prognosis following myocardial infarction.
Clinical science (London, England : 1979) 2007;112(9):477-84.
2007: Sohail Q Khan; Sanjay S Bhandari; Paulene Quinn; Joan E Davies; Leong L Ng
Urotensin II is raised in acute myocardial infarction and low levels predict risk of adverse clinical outcome in humans.
International journal of cardiology 2007;117(3):323-8.
2007: Dominic Kelly; Peter M Hickey; Joan Davies; Leong L Ng; Derek Chin
Acute management of pregnancy associated cardiomyopathy with cardiac resynchronisation therapy.
European journal of heart failure 2007;9(5):542-4.
2007: Sohail Q Khan; Onkar S Dhillon; Russell J O'brien; Joachim Struck; Paulene A Quinn; Nils G. Morgenthaler; Iain B Squire; Joan E Davies; Andreas Bergmann; Leong L Ng
C-terminal provasopressin (copeptin) as a novel and prognostic marker in acute myocardial infarction: Leicester Acute Myocardial Infarction Peptide (LAMP) study.
Circulation 2007;115(16):2103-10.
2007: Sohail Q Khan; Russell J O'brien; Joachim Struck; Paulene Quinn; Nils G. Morgenthaler; Iain B Squire; Joan Davies; Andreas Bergmann; Leong L Ng
Prognostic value of midregional pro-adrenomedullin in patients with acute myocardial infarction: the LAMP (Leicester Acute Myocardial Infarction Peptide) study.
Journal of the American College of Cardiology 2007;49(14):1525-32.
2007: Dominic Kelly; Gillian W Cockerill; Leong L Ng; Matt Thompson; Sohail Khan; Nilesh J Samani; Iain B Squire
Plasma matrix metalloproteinase-9 and left ventricular remodelling after acute myocardial infarction in man: a prospective cohort study.
European heart journal 2007;28(6):711-8.
2007: Sohail Q Khan; Dominic Kelly; Paulene Quinn; Joan E Davies; Leong L Ng
Myotrophin is a more powerful predictor of major adverse cardiac events following acute coronary syndrome than N-terminal pro-B-type natriuretic peptide.
Clinical science (London, England : 1979) 2007;112(4):251-6.
2007: Jonathan R Emberson; Leong L Ng; Jane Armitage; Louise Bowman; Sarah Parish; Rory Collins
N-terminal Pro-B-type natriuretic peptide, vascular disease risk, and cholesterol reduction among 20,536 patients in the MRC/BHF heart protection study.
Journal of the American College of Cardiology 2007;49(3):311-9.
2006: Richard Willingale; Donald J L Jones; John H Lamb; Paulene Quinn; Peter B Farmer; Leong L Ng
Searching for biomarkers of heart failure in the mass spectra of blood plasma.
Proteomics 2006;6(22):5903-14.
2006: Sohail Q Khan; Dominic Kelly; Paulene Quinn; Joan E Davies; Leong L Ng
Cardiotrophin-1 predicts death or heart failure following acute myocardial infarction.
Journal of cardiac failure 2006;12(8):635-40.
2006: Leong L Ng; Bhupesh Pathik; Ian Loke; Iain B Squire; Joan E Davies
Myeloperoxidase and C-reactive protein augment the specificity of B-type natriuretic peptide in community screening for systolic heart failure.
American heart journal 2006;152(1):94-101.
2006: Leong L Ng; Paulene A Quinn
Measurement of calcium and movement in heart cells.
Methods in molecular biology (Clifton, N.J.) 2006;312():261-8.
2005: George Doukas; Nilesh J Samani; Christos Alexiou; Mehmet Oc; Derek T Chin; Peter G Stafford; Leong L Ng; Tomasz J Spyt
Left atrial radiofrequency ablation during mitral valve surgery for continuous atrial fibrillation: a randomized controlled trial.
JAMA : the journal of the American Medical Association 2005;294(18):2323-9.
2005: Iain B Squire; Stein Ørn; Leong L Ng; Cord Manhenke; Lorraine Shipley; Torbjørn Aarsland; Kenneth Dickstein
Plasma natriuretic peptides up to 2 years after acute myocardial infarction and relation to prognosis: an OPTIMAAL substudy.
Journal of cardiac failure 2005;11(7):492-7.
2005: Simon G Williams; Leong L Ng; Russell J O'Brien; Steve Taylor; D J Wright; Y F Li; Lip-Bun Tan
Complementary roles of simple variables, NYHA and N-BNP, in indicating aerobic capacity and severity of heart failure.
International journal of cardiology 2005;102(2):279-86.
2005: Toryn M Poolman; Leong L Ng; Peter B Farmer; Margaret M Manson
Inhibition of the respiratory burst by resveratrol in human monocytes: correlation with inhibition of PI3K signaling.
Free radical biology & medicine 2005;39(1):118-32.
2005: Martin R Wilkins; Gideon A Paul; Julian W Strange; Nina Tunariu; Wendy Gin-Sing; Winston A Banya; Mark A Westwood; Alexander Stefanidis; Leong L Ng; Dudley J Pennell; Raad H Mohiaddin; Petros Nihoyannopoulos; J Simon R Gibbs
Sildenafil versus Endothelin Receptor Antagonist for Pulmonary Hypertension (SERAPH) study.
American journal of respiratory and critical care medicine 2005;171(11):1292-7.
2005: Leong L Ng; Ian Loke; Joan E Davies; Sandeep Geeranavar; Kamlesh Khunti; Margaret A Stone; Derek T Chin; Iain B Squire
Community screening for left ventricular systolic dysfunction using plasma and urinary natriuretic peptides.
Journal of the American College of Cardiology 2005;45(7):1043-50.
2005: Leong L Ng; Paulene A Quinn
Measurement of calcium and movement in heart cells.
Methods in molecular biology (Clifton, N.J.) 2005;312():261-8.
2005: Simon G Williams; Mark Jackson; Leong L Ng; Diane Barker; Ashish Patwala; Lip-Bun Tan
Exercise duration and peak systolic blood pressure are predictive of mortality in ambulatory patients with mild-moderate chronic heart failure.
Cardiology 2005;104(4):221-6.
2004: Simon G Williams; Leong L Ng; Russell J O'Brien; Steve Taylor; D Jay Wright; Lip-Bun Tan
Is plasma N-BNP a good indicator of the functional reserve of failing hearts? The FRESH-BNP study.
European journal of heart failure 2004;6(7):891-900.
2004: Iain B Squire; Russell J O'brien; Bettina Demme; Joan E Davies; Leong L Ng
N-terminal pro-atrial natriuretic peptide (N-ANP) and N-terminal pro-B-type natriuretic peptide (N-BNP) in the prediction of death and heart failure in unselected patients following acute myocardial infarction.
Clinical science (London, England : 1979) 2004;107(3):309-16.
2004: Iain B Squire; Jon Evans; Leong L Ng; Ian M Loftus; Matthew M Thompson
Plasma MMP-9 and MMP-2 following acute myocardial infarction in man: correlation with echocardiographic and neurohumoral parameters of left ventricular dysfunction.
Journal of cardiac failure 2004;10(4):328-33.
2004: Douglas B Kintner; Gui Su; Brett Lenart; Andy J Ballard; Jamie W Meyer; Leong L Ng; Gary E Shull; Dandan Sun
Increased tolerance to oxygen and glucose deprivation in astrocytes from Na(+)/H(+) exchanger isoform 1 null mice.
American journal of physiology. Cell physiology 2004;287(1):C12-21.
2004: Simon G Williams; Leong L Ng; Russell J O'Brien; Steve Taylor; Yi-Fen Li; Lip-Bun Tan
Comparison of plasma N-brain natriuretic peptide, peak oxygen consumption, and left ventricular ejection fraction for severity of chronic heart failure.
The American journal of cardiology 2004;93(12):1560-1.
2004: Leong L Ng; Ian Loke; Russell J O'brien; Iain B Squire; Joan E Davies
Plasma urocortin in human systolic heart failure.
Clinical science (London, England : 1979) 2004;106(4):383-8.
2004: Leong L Ng; S Geeranavar; Sonja C Jennings; Ian Loke; Russell J O'brien
Diagnosis of heart failure using urinary natriuretic peptides.
Clinical science (London, England : 1979) 2004;106(2):129-33.
2003: Leong L Ng; Ian Loke; Joan E Davies; Kamlesh Khunti; Margaret Stone; Keith Abrams; Derek T Chin; Iain B Squire
Identification of previously undiagnosed left ventricular systolic dysfunction: community screening using natriuretic peptides and electrocardiography.
European journal of heart failure 2003;5(6):775-82.
2003: Rajendra Kumari; Gareth Goh; Leong L Ng; Michael R Boarder
ATP and UTP responses of cultured rat aortic smooth muscle cells revisited: dominance of P2Y2 receptors.
British journal of pharmacology 2003;140(7):1169-76.
2003: Richard K M Wong; Andrew I Pettit; Paulene A Quinn; Sonja C Jennings; Joan E Davies; Leong L Ng
Advanced glycation end products stimulate an enhanced neutrophil respiratory burst mediated through the activation of cytosolic phospholipase A2 and generation of arachidonic Acid.
Circulation 2003;108(15):1858-64.
2003: Ian Loke; Iain B Squire; Joan E Davies; Leong L Ng
Reference ranges for natriuretic peptides for diagnostic use are dependent on age, gender and heart rate.
European journal of heart failure 2003;5(5):599-606.
2003: Russell J O'brien; Ian Loke; Joan E Davies; Iain B Squire; Leong L Ng
Myotrophin in human heart failure.
Journal of the American College of Cardiology 2003;42(4):719-25.
2003: Russell J O'brien; Iain B Squire; Bettina Demme; Joan E Davies; Leong L Ng
Pre-discharge, but not admission, levels of NT-proBNP predict adverse prognosis following acute LVF.
European journal of heart failure 2003;5(4):499-506.
2003: Virginia M Lee; Paulene A Quinn; Sonja C Jennings; Leong L Ng
NADPH oxidase activity in preeclampsia with immortalized lymphoblasts used as models.
Hypertension 2003;41(4):925-31.
2003: Virginia M Lee; Paulene A Quinn; Sonja C Jennings; Leong L Ng
Neutrophil activation and production of reactive oxygen species in pre-eclampsia.
Journal of hypertension 2003;21(2):395-402.
2003: Sadia Janjua; Kevin M Lawrence; Leong L Ng; David S Latchman
The cardioprotective agent urocortin induces expression of CT-1.
Cardiovascular toxicology 2003;3(3):255-62.
2003: Virginia M-Y Lee; Aidan Halligan; Leong L Ng
Neutrophil intracellular pH and Na+/H+ exchanger activity in pre-eclampsia.
Metabolism: clinical and experimental 2003;52(1):87-93.
2002: Leong L Ng; Ian Loke; Russell J O'brien; Iain B Squire; Joan E Davies
Plasma urotensin in human systolic heart failure.
Circulation 2002;106(23):2877-80.
2002: Virginia M Lee; Paulene A Quinn; Sonja C Jennings; Aidan Halligan; Leong L Ng
Altered Na+/H+ exchanger isoform 1 activity in immortalized lymphoblasts from women with pre-eclampsia: evidence for an intermediate phenotype.
Clinical science (London, England : 1979) 2002;103(5):503-9.
2002: Oliver Zolk; Leong L Ng; Russell J O'Brien; Michael Weyand; Thomas Eschenhagen
Augmented expression of cardiotrophin-1 in failing human hearts is accompanied by diminished glycoprotein 130 receptor protein abundance.
Circulation 2002;106(12):1442-6.
2002: Richard K M Wong; Andrew I Pettit; Joan E Davies; Leong L Ng
Augmentation of the neutrophil respiratory burst through the action of advanced glycation end products: a potential contributor to vascular oxidant stress.
Diabetes 2002;51(9):2846-53.
2002: Leong L Ng; Russell J O'brien; Bettina Demme; Sonja Jennings
Non-competitive immunochemiluminometric assay for cardiotrophin-1 detects elevated plasma levels in human heart failure.
Clinical science (London, England : 1979) 2002;102(4):411-6.
2002: Andrew I Pettit; Richard K M Wong; Virginia Lee; Sonja Jennings; Paulene A Quinn; Leong L Ng
Increased free radical production in hypertension due to increased expression of the NADPH oxidase subunit p22(phox) in lymphoblast cell lines.
Journal of hypertension 2002;20(4):677-83.
2002: Suneel Talwar; Iain B Squire; Russell J O'brien; Paul F Downie; Joan E Davies; Leong L Ng
Plasma cardiotrophin-1 following acute myocardial infarction: relationship with left ventricular systolic dysfunction.
Clinical science (London, England : 1979) 2002;102(1):9-14.
2001: Paulene A Quinn; Leong L Ng
Potassium and activity of the sodium hydrogen exchanger isoform 1 in vascular smooth muscle of hypertensive rats.
Metabolism: clinical and experimental 2001;50(7):778-82.
2001: V M Lee; A W Halligan; Leong L Ng
Leucocyte intracellular pH and Na+/H+ exchanger isoform-1 activity in postpartum women with pre-eclampsia.
BJOG : an international journal of obstetrics and gynaecology 2001;108(6):615-22.
2001: Paul F Downie; Suneel Talwar; Iain B Squire; Joan E Davies; Leong L Ng
Prolonged stability of endogenous cardiotrophin-1 in whole blood.
Metabolism: clinical and experimental 2001;50(2):237-40.
2001: Suneel Talwar; Paul F Downie; Iain B Squire; Joan E Davies; DB Barnett; Leong L Ng
Plasma N-terminal pro BNP and cardiotrophin-1 are elevated in aortic stenosis.
European journal of heart failure 2001;3(1):15-9.
2000: Suneel Talwar; Iain B Squire; Joan E Davies; Leong L Ng
The effect of valvular regurgitation on plasma Cardiotrophin-1 in patients with normal left ventricular systolic function.
European journal of heart failure 2000;2(4):387-91.
2000: Pamela J White; R Kumari; K E Porter; N J London; Leong L Ng; Michael R Boarder
Antiproliferative effect of UTP on human arterial and venous smooth muscle cells.
American journal of physiology. Heart and circulatory physiology 2000;279(6):H2735-42.
2000: Suneel Talwar; Iain B Squire; Paul F Downie; Joan E Davies; Leong L Ng
Plasma N terminal pro-brain natriuretic peptide and cardiotrophin 1 are raised in unstable angina.
Heart (British Cardiac Society) 2000;84(4):421-4.
2000: Suneel Talwar; Iain B Squire; Paul F Downie; A M Mccullough; M C Campton; Joan E Davies; DB Barnett; Leong L Ng
Profile of plasma N-terminal proBNP following acute myocardial infarction; correlation with left ventricular systolic dysfunction.
European heart journal 2000;21(18):1514-21.
2000: Suneel Talwar; Iain B Squire; Paul F Downie; Russell J O'brien; Joan E Davies; Leong L Ng
Elevated circulating cardiotrophin-1 in heart failure: relationship with parameters of left ventricular systolic dysfunction.
Clinical science (London, England : 1979) 2000;99(1):83-8.
2000: Leong L Ng; Paulene A Quinn; F Baker; S J Carr
Red cell Na+/Li+ countertransport and Na+/H+ exchanger isoforms in human proximal tubules.
Kidney international 2000;58(1):229-35.
2000: Suneel Talwar; Paul F Downie; Leong L Ng; Iain B Squire
Towards a blood test for heart failure: the potential use of circulating natriuretic peptides.
British journal of clinical pharmacology 2000;50(1):15-20.
2000: Leong L Ng; S Jennings; Joan E Davies; Paulene A Quinn
Na+/H+ exchanger activity and phosphorylation in temperature-sensitive immortalized proximal tubule cell lines derived from the spontaneously hypertensive rat.
Clinical science (London, England : 1979) 2000;98(4):409-18.
1999: Suneel Talwar; Iain B Squire; Joan E Davies; DB Barnett; Leong L Ng
Plasma N-terminal pro-brain natriuretic peptide and the ECG in the assessment of left-ventricular systolic dysfunction in a high risk population.
European heart journal 1999;20(23):1736-44.
1999: Paul F Downie; Suneel Talwar; Iain B Squire; Joan E Davies; DB Barnett; Leong L Ng
Assessment of the stability of N-terminal pro-brain natriuretic peptide in vitro: implications for assessment of left ventricular dysfunction.
Clinical science (London, England : 1979) 1999;97(3):255-8.
1999: Suneel Talwar; Paul F Downie; Iain B Squire; DB Barnett; J D Davies; Leong L Ng
An immunoluminometric assay for cardiotrophin-1: a newly identified cytokine is present in normal human plasma and is increased in heart failure.
Biochemical and biophysical research communications 1999;261(3):567-71.
1999: S A Frantz; A S Thiara; David Lodwick; Leong L Ng; Ian C Eperon; Nilesh J Samani
Exon repetition in mRNA.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(10):5400-5.
1999: D Hughes; Suneel Talwar; Iain B Squire; Joan E Davies; Leong L Ng
An immunoluminometric assay for N-terminal pro-brain natriuretic peptide: development of a test for left ventricular dysfunction.
Clinical science (London, England : 1979) 1999;96(4):373-80.
1999: Leong L Ng; Paulene A Quinn
Measurement of calcium and movement in heart cells.
Methods in molecular biology (Clifton, N.J.) 1999;114():279-86.
1998: S Harper; Tania E Webb; Steven J Charlton; Leong L Ng; Michael R Boarder
Evidence that P2Y4 nucleotide receptors are involved in the regulation of rat aortic smooth muscle cells by UTP and ATP.
British journal of pharmacology 1998;124(4):703-10.
1998: Leong L Ng; F C Ngkeekwong; Paulene A Quinn; Joan E Davies
Uptake mechanisms for ascorbate and dehydroascorbate in lymphoblasts from diabetic nephropathy and hypertensive patients.
Diabetologia 1998;41(4):435-42.
1997: N Wilkie; Leong L Ng; Michael R Boarder
Angiotensin II responses of vascular smooth muscle cells from hypertensive rats: enhancement at the level of p42 and p44 mitogen activated protein kinase.
British journal of pharmacology 1997;122(2):209-16.
1997: M P Kelly; Paulene A Quinn; Joan E Davies; Leong L Ng
Activity and expression of Na(+)-H+ exchanger isoforms 1 and 3 in kidney proximal tubules of hypertensive rats.
Circulation research 1997;80(6):853-60.
1997: F C Ngkeekwong; Leong L Ng
Two distinct uptake mechanisms for ascorbate and dehydroascorbate in human lymphoblasts and their interaction with glucose.
The Biochemical journal 1997;324 ( Pt 1)():225-30.
1997: F P Sweeney; Paulene A Quinn; Leong L Ng
Enhanced mitogen-activated protein kinase activity and phosphorylation of the Na+/H+ exchanger isoform-1 of human lymphoblasts in hypertension.
Metabolism: clinical and experimental 1997;46(3):297-302.
1997: M Siczkowski; Paulene A Quinn; Leong L Ng
Calcium-induced activation of the rat vascular myocyte Na+/H+ exchanger isoform-1.
Metabolism: clinical and experimental 1997;46(3):250-6.
1996: N Wilkie; C Morton; Leong L Ng; Michael R Boarder
Stimulated mitogen-activated protein kinase is necessary but not sufficient for the mitogenic response to angiotensin II. A role for phospholipase D.
The Journal of biological chemistry 1996;271(50):32447-53.
1996: M Siczkowski; Leong L Ng
Phorbol ester activation of the rat vascular myocyte Na(+)-H(+) exchanger isoform 1.
Hypertension 1996;27(4):859-66.
1996: N Wilkie; Leong L Ng; Michael R Boarder
Vascular smooth muscle cells from spontaneously hypertensive rats exhibit increased MAPK response to angiotensin II and phorbol ester stimulation.
Biochemical Society transactions 1996;24(1):65S.
1996: M Siczkowski; Leong L Ng
Glucose-induced changes in activity and phosphorylation of the Na+/H+ exchanger, NHE-1, in vascular myocytes from Wistar-Kyoto and spontaneously hypertensive rats.
Metabolism: clinical and experimental 1996;45(1):114-9.
1995: F P Sweeney; M Siczkowski; J E Davies; Paulene A Quinn; J McDonald; B Krolewski; Andrzej S Krolewski; Leong L Ng
Phosphorylation and activity of Na+/H+ exchanger isoform 1 of immortalized lymphoblasts in diabetic nephropathy.
Diabetes 1995;44(10):1180-5.
1995: M Siczkowski; J E Davies; F P Sweeney; A Kofoed-Enevoldsen; Leong L Ng
Na+/H+ exchanger isoform-1 abundance in skin fibroblasts of type I diabetic patients with nephropathy.
Metabolism: clinical and experimental 1995;44(6):791-5.
1995: Leong L Ng; F P Sweeney; M Siczkowski; J E Davies; Paulene A Quinn; B Krolewski; Andrzej S Krolewski
Na(+)-H+ antiporter phenotype, abundance, and phosphorylation of immortalized lymphoblasts from humans with hypertension.
Hypertension 1995;25(5):971-7.
1995: M Siczkowski; J E Davies; Leong L Ng
Na(+)-H+ exchanger isoform 1 phosphorylation in normal Wistar-Kyoto and spontaneously hypertensive rats.
Circulation research 1995;76(5):825-31.
1995: M Siczkowski; Leong L Ng
Culture density and the activity, abundance and phosphorylation of the Na+/H+ exchanger isoform 1 in human fibroblasts.
Biochemical and biophysical research communications 1995;209(1):191-7.
1995: J E Davies; M Siczkowski; F P Sweeney; Paulene A Quinn; B Krolewski; Andrzej S Krolewski; Leong L Ng
Glucose-induced changes in turnover of Na+/H+ exchanger of immortalized lymphoblasts from type I diabetic patients with nephropathy.
Diabetes 1995;44(4):382-8.
1994: M Siczkowski; Joan E Davies; Leong L Ng
Activity and density of the Na+/H+ antiporter in normal and transformed human lymphocytes and fibroblasts.
The American journal of physiology 1994;267(3 Pt 1):C745-52.
1994: M Siczkowski; J E Davies; Leong L Ng
Sodium-hydrogen antiporter protein in normotensive Wistar-Kyoto rats and spontaneously hypertensive rats.
Journal of hypertension 1994;12(7):775-81.
1994: Leong L Ng; J E Davies; M Siczkowski; F P Sweeney; Paulene A Quinn; B Krolewski; Andrzej S Krolewski
Abnormal Na+/H+ antiporter phenotype and turnover of immortalized lymphoblasts from type 1 diabetic patients with nephropathy.
The Journal of clinical investigation 1994;93(6):2750-7.
1994: Leong L Ng; Joan E Davies; R J Wojcikiewicz
3-Hydroxy-3-methyl glutaryl coenzyme A reductase inhibition modulates vasopressin-stimulated Ca2+ responses in rat A10 vascular smooth muscle cells.
Circulation research 1994;74(2):173-81.
1993: Joan E Davies; Leong L Ng
Simvastatin and intracellular pH regulation by the Na+/H+ antiport of SV40-virus-transformed human MRC5 fibroblasts.
Clinical science (London, England : 1979) 1993;84(6):633-43.
1993: Leong L Ng; P Delva; Joan E Davies
Intracellular pH regulation of SV-40 virus transformed human MRC-5 fibroblasts and cell membrane cholesterol.
The American journal of physiology 1993;264(4 Pt 1):C789-93.
1993: Leong L Ng; Joan E Davies; P Quinn
Intracellular pH regulation in isolated myocytes from adult rat heart in HCO3(-)-containing and HCO3(-)-free media.
Clinical science (London, England : 1979) 1993;84(2):133-9.
1992: Joan E Davies; Leong L Ng; A Kofoed-Enevoldsen; L K Li; K A Earle; Roberto Trevisan; Giancarlo Viberti
Intracellular pH and Na+/H+ antiport activity of cultured skin fibroblasts from diabetics.
Kidney international 1992;42(5):1184-90.
1992: Leong L Ng; Joan E Davies
Abnormalities in Na+/H+ antiporter activity in diabetic nephropathy.
Journal of the American Society of Nephrology : JASN 1992;3(4 Suppl):S50-5.
1992: Leong L Ng; Joan E Davies
Lipids and cellular Na+/H+ antiport activity in diabetic nephropathy.
Kidney international 1992;41(4):872-6.
1991: Leong L Ng; Joan E Davies
HMG CoA reductase inhibitors affect Na(+)-H+ antiport activity in human lymphoblasts.
The American journal of physiology 1991;261(5 Pt 1):C780-6.
1991: Leong L Ng; Joan E Davies; M C Garrido
Intracellular free magnesium in human lymphocytes and the response to lectins.
Clinical science (London, England : 1979) 1991;80(6):539-47.