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Tri Nguyen

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Lucas L Falke; Roel Broekhuizen; Amélie Dendooven; Jaap A Joles; Hans Kemperman; Jan Willem Leeuwis; Karen Lyons; Tri Q Nguyen; Reinier O Schlingemann; Reinout Stoop; Dionne M van der Giezen; Rob J van Geest; roel goldschmeding
Hemizygous deletion of CTGF/CCN2 does not suffice to prevent fibrosis of the severely injured kidney.
Karin G Gerritsen; roel goldschmeding; Jaap A Joles; Maarten P Koeners; Alferso C Abrahams; Peter J Blankestijn; Claire H den Hoedt; Amelie Dendooven; Tri Q Nguyen; Hilde P Peters; Marinus Van den Dorpel; Jack F Wetzels; Robbert J Kok
Effect of GFR on plasma N-terminal connective tissue growth factor (CTGF) concentrations.
John A Jansen; Ronald Labzowski; Tri Q Nguyen; Carolin M Oefner; Roel van der Nagel; Astrid A Bosch; Jacques M T de Bakker; Sanne de Jong; Helen Driessen; roel goldschmeding; Leonie van Stuijvenberg; Toon A B van Veen; Marc A Vos; Harold V M van Rijen
Reduced Cx43 expression triggers increased fibrosis due to enhanced fibroblast activity.

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All Publications

2012: Lucas L Falke; Roel Broekhuizen; Amélie Dendooven; Jaap A Joles; Hans Kemperman; Jan Willem Leeuwis; Karen Lyons; Tri Q Nguyen; Reinier O Schlingemann; Reinout Stoop; Dionne M van der Giezen; Rob J van Geest; roel goldschmeding
Hemizygous deletion of CTGF/CCN2 does not suffice to prevent fibrosis of the severely injured kidney.
Matrix biology : journal of the International Society for Matrix Biology 2012;31(7-8):421-31.
2012: Karin G Gerritsen; roel goldschmeding; Jaap A Joles; Maarten P Koeners; Alferso C Abrahams; Peter J Blankestijn; Claire H den Hoedt; Amelie Dendooven; Tri Q Nguyen; Hilde P Peters; Marinus Van den Dorpel; Jack F Wetzels; Robbert J Kok
Effect of GFR on plasma N-terminal connective tissue growth factor (CTGF) concentrations.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2012;59(5):619-27.
2012: John A Jansen; Ronald Labzowski; Tri Q Nguyen; Carolin M Oefner; Roel van der Nagel; Astrid A Bosch; Jacques M T de Bakker; Sanne de Jong; Helen Driessen; roel goldschmeding; Leonie van Stuijvenberg; Toon A B van Veen; Marc A Vos; Harold V M van Rijen
Reduced Cx43 expression triggers increased fibrosis due to enhanced fibroblast activity.
Circulation. Arrhythmia and electrophysiology 2012;5(2):380-90.
2012: Arianne van Koppen; Lennart Bongartz; roel goldschmeding; Jaap A Joles; Tri Q Nguyen; Holger M Reichardt; Jens van den Brandt; Marianne C Verhaar
Healthy bone marrow cells reduce progression of kidney failure better than CKD bone marrow cells in rats with established chronic kidney disease.
Cell transplantation 2012;21(10):2299-312.
2012: Stefan H van Vuuren; Roel Broekhuizen; roel goldschmeding; Marc R Lilien; Tri Q Nguyen; Michiel J S Oosterveld; Chalana M Sol; Tom P V M de Jong
Compensatory growth of congenital solitary kidneys in pigs reflects increased nephron numbers rather than hypertrophy.
PloS one 2012;7(11):e49735.
2011: Tri Q Nguyen; Karin G Gerritsen; roel goldschmeding
Does high or low urinary connective tissue growth factor predict CKD?
American journal of kidney diseases : the official journal of the National Kidney Foundation 2011;58(4):680-1; author reply 681-2.
2011: Maartje C J Slagman; Liffert Vogt; Femke Waanders; Tri Q Nguyen; roel goldschmeding; MH Hemmelder; Gozewijn D Laverman; gerjan navis
Effects of antiproteinuric intervention on elevated connective tissue growth factor (CTGF/CCN-2) plasma and urine levels in nondiabetic nephropathy.
Clinical journal of the American Society of Nephrology : CJASN 2011;6(8):1845-50.
2011: Amélie Dendooven; Karin G Gerritsen; Tri Q Nguyen; Robbert J Kok; roel goldschmeding
Connective tissue growth factor (CTGF/CCN2) ELISA: a novel tool for monitoring fibrosis.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2011;16(4):289-301.
2011: Amélie Dendooven; David A Ishola; Tri Q Nguyen; Dionne M van der Giezen; Robbert Jan Kok; roel goldschmeding; Jaap A Joles
Oxidative stress in obstructive nephropathy.
International journal of experimental pathology 2011;92(3):202-10.
2011: Jan Willem Leeuwis; Tri Q Nguyen; Susana M Chuva de Sousa Lopes; Dionne M van der Giezen; Kevin van der Ven; Peter J H Rouw; G Johan A Offerhaus; Christine L Mummery; roel goldschmeding
Direct visualization of Smad1/5/8-mediated transcriptional activity identifies podocytes and collecting ducts as major targets of BMP signalling in healthy and diseased kidneys.
The Journal of pathology 2011;224(1):121-32.
2011: Amélie Dendooven; Olivia van Oostrom; Dionne M van der Giezen; Jan Willem Leeuwis; Cristel Snijckers; Jaap A Joles; Elizabeth J Robertson; Marianne C Verhaar; Tri Q Nguyen; roel goldschmeding
Loss of endogenous bone morphogenetic protein-6 aggravates renal fibrosis.
The American journal of pathology 2011;178(3):1069-79.
2011: Amélie Dendooven; Lodewijk Brosens; Dongxia Li; Tri Q Nguyen; Hans-Henrik Parving; Peter Rossing; Lise Tarnow; roel goldschmeding
The CTGF -945GC polymorphism is not associated with plasma CTGF and does not predict nephropathy or outcome in type 1 diabetes.
Journal of negative results in biomedicine 2011;10():4.
2011: Y Ito; Jan Aten; Tri Q Nguyen; Jaap A Joles; Seiichi Matsuo; Jan J Weening; roel goldschmeding
Involvement of connective tissue growth factor in human and experimental hypertensive nephrosclerosis.
Nephron. Experimental nephrology 2011;117(1):e9-20.
2010: Jan Willem Leeuwis; Tri Q Nguyen; Maarten G J Theunissen; Wouter Peeters; roel goldschmeding; Gerard Pasterkamp; Aryan Vink
Connective tissue growth factor is associated with a stable atherosclerotic plaque phenotype and is involved in plaque stabilization after stroke.
Stroke; a journal of cerebral circulation 2010;41(12):2979-81.
2010: Jan Willem Leeuwis; Tri Q Nguyen; Amélie Dendooven; Robbert J Kok; roel goldschmeding
Targeting podocyte-associated diseases.
Advanced drug delivery reviews 2010;62(14):1325-36.
2010: Melissa Heard; Claude V Maina; Benjamin E Morehead; Marius C Hoener; Tri Q Nguyen; Christopher C Williams; Brian G Rowan; Chris R Gissendanner
A functional NR4A nuclear receptor DNA-binding domain is required for organ development in Caenorhabditis elegans.
Genesis (New York, N.Y. : 2000) 2010;48(8):485-91.
2010: Karin G Gerritsen; Hilde P Peters; Tri Q Nguyen; Maarten P Koeners; Jack F Wetzels; Jaap A Joles; Erik I Christensen; Pierre J Verroust; Dongxia Li; Noelynn Oliver; Leon Xu; Robbert J Kok; roel goldschmeding
Renal proximal tubular dysfunction is a major determinant of urinary connective tissue growth factor excretion.
American journal of physiology. Renal physiology 2010;298(6):F1457-64.
2010: Peter E Westerweel; Cindy T J van Velthoven; Tri Q Nguyen; Krista den Ouden; Dominique P V de Kleijn; Marie-José Goumans; roel goldschmeding; Marianne C Verhaar
Modulation of TGF-β/BMP-6 expression and increased levels of circulating smooth muscle progenitor cells in a type I diabetes mouse model.
Cardiovascular diabetology 2010;9():55.
2009: Mangalakumar Veerasamy; Tri Q Nguyen; Reza Motazed; Alexander L Pearson; roel goldschmeding; Mark Dockrell
Differential regulation of E-cadherin and alpha-smooth muscle actin by BMP 7 in human renal proximal tubule epithelial cells and its implication in renal fibrosis.
American journal of physiology. Renal physiology 2009;297(5):F1238-48.
2009: Windy Berkofsky-Fessler; Tri Q Nguyen; Paul Delmar; Juliette Molnos; Charu Kanwal; Wanda DePinto; James Rosinski; Patricia McLoughlin; Steve Ritland; Mark DeMario; Krishna Tobon; John Reidhaar-Olson; Ruediger Rueger; Holly Hilton
Preclinical biomarkers for a cyclin-dependent kinase inhibitor translate to candidate pharmacodynamic biomarkers in phase I patients.
Molecular cancer therapeutics 2009;8(9):2517-25.
2009: Tamara Turk; Jan Willem Leeuwis; Julia Gray; Suzy V Torti; Karen M Lyons; Tri Q Nguyen; roel goldschmeding
BMP signaling and podocyte markers are decreased in human diabetic nephropathy in association with CTGF overexpression.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2009;57(7):623-31.
2008: Marjan M Fretz; M E Emmy M Dolman; Marie Lacombe; Jai Prakash; Tri Q Nguyen; roel goldschmeding; Janos Pato; Gert Storm; Wim E Hennink; Robbert J Kok
Intervention in growth factor activated signaling pathways by renally targeted kinase inhibitors.
Journal of controlled release : official journal of the Controlled Release Society 2008;132(3):200-7.
2008: Tri Q Nguyen; Peggy Roestenberg; Frans A van Nieuwenhoven; Niels Bovenschen; Zeke Li; Leon Xu; Noelynn Oliver; Jan Aten; Jaap A Joles; Cecilia Vial; Enrique Brandan; Karen M Lyons; roel goldschmeding
CTGF inhibits BMP-7 signaling in diabetic nephropathy.
Journal of the American Society of Nephrology : JASN 2008;19(11):2098-107.
2008: Daphne H T IJpelaar; Alton B Farris; Natascha Goemaere; Kerstin Amann; roel goldschmeding; Tri Q Nguyen; Evan Farkash; Marius C van den Heuvel; Emile de Heer; Jan A Bruijn; Robert Colvin; Ingeborg M Bajema
Fidelity and evolution of recurrent FSGS in renal allografts.
Journal of the American Society of Nephrology : JASN 2008;19(11):2219-24.
2008: Tri Q Nguyen; roel goldschmeding
Bone morphogenetic protein-7 and connective tissue growth factor: novel targets for treatment of renal fibrosis?
Pharmaceutical research 2008;25(10):2416-26.
2008: Tri Q Nguyen; Lise Tarnow; Anders Jorsal; Noelynn Oliver; Peggy Roestenberg; Yasuhiko Ito; Hans-Henrik Parving; Peter Rossing; Frans A van Nieuwenhoven; roel goldschmeding
Plasma connective tissue growth factor is an independent predictor of end-stage renal disease and mortality in type 1 diabetic nephropathy.
Diabetes care 2008;31(6):1177-82.
2008: Peter E Westerweel; Krista den Ouden; Tri Q Nguyen; roel goldschmeding; Jaap A Joles; Marianne C Verhaar
Amelioration of anti-Thy1-glomerulonephritis by PPAR-gamma agonism without increase of endothelial progenitor cell homing.
American journal of physiology. Renal physiology 2008;294(2):F379-84.
2008: Chris R Gissendanner; Kristopher Kelley; Tri Q Nguyen; Marius C Hoener; Ann E Sluder; Claude V Maina
The Caenorhabditis elegans NR4A nuclear receptor is required for spermatheca morphogenesis.
Developmental biology 2008;313(2):767-86.
2007: K van der Ven; Tri Q Nguyen; roel goldschmeding
Immunofluorescence on proteinase XXIV-digested paraffin sections.
Kidney international 2007;72(7):896.
2006: Tri Q Nguyen; Helena Chon; Frans A van Nieuwenhoven; Branko Braam; Marianne C Verhaar; roel goldschmeding
Myofibroblast progenitor cells are increased in number in patients with type 1 diabetes and express less bone morphogenetic protein 6: a novel clue to adverse tissue remodelling?
Diabetologia 2006;49(5):1039-48.
2006: Tri Q Nguyen; Lise Tarnow; Steen Andersen; Peter Hovind; Hans-Henrik Parving; roel goldschmeding; Frans A van Nieuwenhoven
Urinary connective tissue growth factor excretion correlates with clinical markers of renal disease in a large population of type 1 diabetic patients with diabetic nephropathy.
Diabetes care 2006;29(1):83-8.