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John Nicholas

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.8 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Living Beings

Concepts & Ideas

Genes & Molecular Sequences

Chemicals & Drugs

Disorders

Kaposi Sarcoma

Anatomy

Cell Line

Procedures

Restriction Mapping

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Co-Publications
Name
8
Reitz, Marvin
8
Hayward, Gary
6
SANDFORD, GORDON
5
Guo, Hong-Guang
4
Ciufo, Dolores
4
Wan, X
4
zong, jianchao
3
Albrecht, Jens-Christian
3
Browning, Philip
3
Gompels, Ursula
3
Secchiero, Paola
3
Fleckenstein, Bernhard
2
Orenstein, Jan
2
Hardwick, Marie
2
Dewhurst, Stephen

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Publications

TOP 3
Choi Young Bong; Nicholas John
Bim nuclear translocation and inactivation by viral interferon regulatory factor.
Choi Young Bong; Nicholas John
Induction of angiogenic chemokine CCL2 by human herpesvirus 8 chemokine receptor.
Sandford Gordon; Choi Young Bong; Nicholas John
Role of ORF74-encoded viral G protein-coupled receptor in human herpesvirus 8 lytic replication.

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All Publications

2010: Choi Young Bong; Nicholas John
Bim nuclear translocation and inactivation by viral interferon regulatory factor.
PLoS pathogens 2010;6(8):.
2010: Choi Young Bong; Nicholas John
Induction of angiogenic chemokine CCL2 by human herpesvirus 8 chemokine receptor.
Virology 2010;397(2):369-78.
2009: Sandford Gordon; Choi Young Bong; Nicholas John
Role of ORF74-encoded viral G protein-coupled receptor in human herpesvirus 8 lytic replication.
Journal of virology 2009;83(24):13009-14.
2009: Chen Daming; Choi Young Bong; Sandford Gordon; Nicholas John
Determinants of secretion and intracellular localization of human herpesvirus 8 interleukin-6.
Journal of virology 2009;83(13):6874-82.
2009: Chen Daming; Sandford Gordon; Nicholas John
Intracellular signaling mechanisms and activities of human herpesvirus 8 interleukin-6.
Journal of virology 2009;83(2):722-33.
2008: Choi Young Bong; Nicholas John
Autocrine and paracrine promotion of cell survival and virus replication by human herpesvirus 8 chemokines.
Journal of virology 2008;82(13):6501-13.
2007: Nicholas John
Human herpesvirus 8-encoded proteins with potential roles in virus-associated neoplasia.
Frontiers in bioscience : a journal and virtual library 2007;12():265-81.
2006: Verzijl Dennis; Pardo Leonardo; van Dijk Marie; Gruijthuijsen Yvonne K; Jongejan Aldo; Timmerman Henk; Nicholas John; Schwarz Mario; Murphy Philip M; Leurs Rob; Smit Martine J
Helix 8 of the viral chemokine receptor ORF74 directs chemokine binding.
The Journal of biological chemistry 2006;281(46):35327-35.
2006: Hu Fang; Nicholas John
Signal transduction by human herpesvirus 8 viral interleukin-6 (vIL-6) is modulated by the nonsignaling gp80 subunit of the IL-6 receptor complex and is distinct from signaling induced by human IL-6.
Journal of virology 2006;80(21):10874-8.
2006: Chen Daming; Nicholas John
Structural requirements for gp80 independence of human herpesvirus 8 interleukin-6 (vIL-6) and evidence for gp80 stabilization of gp130 signaling complexes induced by vIL-6.
Journal of virology 2006;80(19):9811-21.
2005: Nicholas John
Human gammaherpesvirus cytokines and chemokine receptors.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2005;25(7):373-83.
2004: Liu Chaoqi; Sandford Gordon; Fei Guo; Nicholas John
Galpha protein selectivity determinant specified by a viral chemokine receptor-conserved region in the C tail of the human herpesvirus 8 g protein-coupled receptor.
Journal of virology 2004;78(5):2460-71.
2004: Boulanger Martin J; Chow Dar-chone; Brevnova Elena; Martick Monika; Sandford Gordon; Nicholas John; Garcia K Christopher
Molecular mechanisms for viral mimicry of a human cytokine: activation of gp130 by HHV-8 interleukin-6.
Journal of molecular biology 2004;335(2):641-54.
2003: Nicholas John
Human herpesvirus-8-encoded signalling ligands and receptors.
Journal of biomedical science 2003;10(5):475-89.
2002: Li Hong; Nicholas John
Identification of amino acid residues of gp130 signal transducer and gp80 alpha receptor subunit that are involved in ligand binding and signaling by human herpesvirus 8-encoded interleukin-6.
Journal of virology 2002;76(11):5627-36.
2001: Liu C; Okruzhnov Y; Li H; Nicholas J
Human herpesvirus 8 (HHV-8)-encoded cytokines induce expression of and autocrine signaling by vascular endothelial growth factor (VEGF) in HHV-8-infected primary-effusion lymphoma cell lines and mediate VEGF-independent antiapoptotic effects.
Journal of virology 2001;75(22):10933-40.
2001: Li H; Wang H; Nicholas J
Detection of direct binding of human herpesvirus 8-encoded interleukin-6 (vIL-6) to both gp130 and IL-6 receptor (IL-6R) and identification of amino acid residues of vIL-6 important for IL-6R-dependent and -independent signaling.
Journal of virology 2001;75(7):3325-34.
2000: Nicholas J
Evolutionary aspects of oncogenic herpesviruses.
Molecular pathology : MP 2000;53(5):222-37.
1999: Wan X; Wang H; Nicholas J
Human herpesvirus 8 interleukin-6 (vIL-6) signals through gp130 but has structural and receptor-binding properties distinct from those of human IL-6.
Journal of virology 1999;73(10):8268-78.
1999: Cannon J S; Nicholas J; Orenstein J M; Mann R B; Murray P G; Browning P J; DiGiuseppe J A; Cesarman E; Hayward G S; Ambinder R F
Heterogeneity of viral IL-6 expression in HHV-8-associated diseases.
The Journal of infectious diseases 1999;180(3):824-8.
1999: Cannon J S; Hamzeh F; Moore S; Nicholas J; Ambinder R F
Human herpesvirus 8-encoded thymidine kinase and phosphotransferase homologues confer sensitivity to ganciclovir.
Journal of virology 1999;73(6):4786-93.
1999: Zong J C; Ciufo D M; Alcendor D J; Wan X; Nicholas J; Browning P J; Rady P L; Tyring S K; Orenstein J M; Rabkin C S; Su I J; Powell K F; Croxson M; Foreman K E; Nickoloff B J; Alkan S; Hayward G S
High-level variability in the ORF-K1 membrane protein gene at the left end of the Kaposi's sarcoma-associated herpesvirus genome defines four major virus subtypes and multiple variants or clades in different human populations.
Journal of virology 1999;73(5):4156-70.
1998: Nicholas J; Zong J C; Alcendor D J; Ciufo D M; Poole L J; Sarisky R T; Chiou C J; Zhang X; Wan X; Guo H G; Reitz M S; Hayward G S
Novel organizational features, captured cellular genes, and strain variability within the genome of KSHV/HHV8.
Journal of the National Cancer Institute. Monographs 1998;(23):79-88.
1997: van Loon N; Dykes C; Deng H; Dominguez G; Nicholas J; Dewhurst S
Identification and analysis of a lytic-phase origin of DNA replication in human herpesvirus 7.
Journal of virology 1997;71(4):3279-84.
1997: Nicholas J; Ruvolo V R; Burns W H; Sandford G; Wan X; Ciufo D; Hendrickson S B; Guo H G; Hayward G S; Reitz M S
Kaposi's sarcoma-associated human herpesvirus-8 encodes homologues of macrophage inflammatory protein-1 and interleukin-6.
Nature medicine 1997;3(3):287-92.
1997: Zong J C; Metroka C; Reitz M S; Nicholas J; Hayward G S
Strain variability among Kaposi sarcoma-associated herpesvirus (human herpesvirus 8) genomes: evidence that a large cohort of United States AIDS patients may have been infected by a single common isolate.
Journal of virology 1997;71(3):2505-11.
1997: Nicholas J; Ruvolo V; Zong J; Ciufo D; Guo H G; Reitz M S; Hayward G S
A single 13-kilobase divergent locus in the Kaposi sarcoma-associated herpesvirus (human herpesvirus 8) genome contains nine open reading frames that are homologous to or related to cellular proteins.
Journal of virology 1997;71(3):1963-74.
1997: Guo H G; Browning P; Nicholas J; Hayward G S; Tschachler E; Jiang Y W; Sadowska M; Raffeld M; Colombini S; Gallo R C; Reitz M S
Characterization of a chemokine receptor-related gene in human herpesvirus 8 and its expression in Kaposi's sarcoma.
Virology 1997;228(2):371-8.
1997: Cheng E H; Nicholas J; Bellows D S; Hayward G S; Guo H G; Reitz M S; Hardwick J M
A Bcl-2 homolog encoded by Kaposi sarcoma-associated virus, human herpesvirus 8, inhibits apoptosis but does not heterodimerize with Bax or Bak.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(2):690-4.
1997: Secchiero P; Berneman Z N; Sun D; Nicholas J; Reitz M S
Identification of envelope glycoproteins H and B homologues of human herpesvirus 7.
Intervirology 1997;40(1):22-32.
1996: Nicholas J
Determination and analysis of the complete nucleotide sequence of human herpesvirus.
Journal of virology 1996;70(9):5975-89.
1996: Ruvolo V R; Berneman Z; Secchiero P; Nicholas J
Cloning, restriction endonuclease mapping and partial sequence analysis of the genome of human herpesvirus 7 strain JI.
The Journal of general virology 1996;77 ( Pt 8)():1901-12.
1995: Secchiero P; Nicholas J; Deng H; Xiaopeng T; van Loon N; Ruvolo V R; Berneman Z N; Reitz M S; Dewhurst S
Identification of human telomeric repeat motifs at the genome termini of human herpesvirus 7: structural analysis and heterogeneity.
Journal of virology 1995;69(12):8041-5.
1995: Gompels U A; Nicholas J; Lawrence G; Jones M; Thomson B J; Martin M E; Efstathiou S; Craxton M; Macaulay H A
The DNA sequence of human herpesvirus-6: structure, coding content, and genome evolution.
Virology 1995;209(1):29-51.
1995: Lawrence G L; Nicholas J; Barrell B G
Human herpesvirus 6 (strain U1102) encodes homologues of the conserved herpesvirus glycoprotein gM and the alphaherpesvirus origin-binding protein.
The Journal of general virology 1995;76 ( Pt 1)():147-52.
1994: Nicholas J
Nucleotide sequence analysis of a 21-kbp region of the genome of human herpesvirus-6 containing homologues of human cytomegalovirus major immediate-early and replication genes.
Virology 1994;204(2):738-50.
1994: Nicholas J; Martin M E
Nucleotide sequence analysis of a 38.5-kilobase-pair region of the genome of human herpesvirus 6 encoding human cytomegalovirus immediate-early gene homologs and transactivating functions.
Journal of virology 1994;68(2):597-610.
1993: Liu D X; Gompels U A; Nicholas J; Lelliott C
Identification and expression of the human herpesvirus 6 glycoprotein H and interaction with an accessory 40K glycoprotein.
The Journal of general virology 1993;74 ( Pt 9)():1847-57.
1992: Bublot M; Lomonte P; Lequarre A S; Albrecht J C; Nicholas J; Fleckenstein B; Pastoret P P; Thiry E
Genetic relationships between bovine herpesvirus 4 and the gammaherpesviruses Epstein-Barr virus and herpesvirus saimiri.
Virology 1992;190(2):654-65.
1992: Albrecht J C; Nicholas J; Cameron K R; Newman C; Fleckenstein B; Honess R W
Herpesvirus saimiri has a gene specifying a homologue of the cellular membrane glycoprotein CD59.
Virology 1992;190(1):527-30.
1992: Hardwick J M; Tse L; Applegren N; Nicholas J; Veliuona M A
The Epstein-Barr virus R transactivator (Rta) contains a complex, potent activation domain with properties different from those of VP16.
Journal of virology 1992;66(9):5500-8.
1992: Albrecht J C; Nicholas J; Biller D; Cameron K R; Biesinger B; Newman C; Wittmann S; Craxton M A; Coleman H; Fleckenstein B
Primary structure of the herpesvirus saimiri genome.
Journal of virology 1992;66(8):5047-58.
1992: Nicholas J; Cameron K R; Coleman H; Newman C; Honess R W
Analysis of nucleotide sequence of the rightmost 43 kbp of herpesvirus saimiri (HVS) L-DNA: general conservation of genetic organization between HVS and Epstein-Barr virus.
Virology 1992;188(1):296-310.
1992: Nicholas J; Cameron K R; Honess R W
Herpesvirus saimiri encodes homologues of G protein-coupled receptors and cyclins.
Nature 1992;355(6358):362-5.
1991: Martin M E; Nicholas J; Thomson B J; Newman C; Honess R W
Identification of a transactivating function mapping to the putative immediate-early locus of human herpesvirus 6.
Journal of virology 1991;65(10):5381-90.
1991: Nicholas J; Coles L S; Newman C; Honess R W
Regulation of the herpesvirus saimiri (HVS) delayed-early 110-kilodalton promoter by HVS immediate-early gene products and a homolog of the Epstein-Barr virus R trans activator.
Journal of virology 1991;65(5):2457-66.
1991: Nicholas J; Nevins J R
Distinct DNA targets for trans-activation by HTLV-1 tax and adenovirus E1A.
Virology 1991;182(1):156-67.
1990: Nicholas J; Smith E P; Coles L; Honess R
Gene expression in cells infected with gammaherpesvirus saimiri: properties of transcripts from two immediate-early genes.
Virology 1990;179(1):189-200.
1988: Nicholas J; Gompels U A; Craxton M A; Honess R W
Conservation of sequence and function between the product of the 52-kilodalton immediate-early gene of herpesvirus saimiri and the BMLF1-encoded transcriptional effector (EB2) of Epstein-Barr virus.
Journal of virology 1988;62(9):3250-7.

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