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Janice Nicklas

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Richard J Albertini; Radim J Sram; Pamela M Vacek; Jeremiah Lynch; Pavel Rossner; Janice A Nicklas; Jake D McDonald; Gunnar Boysen; Nadia I Georgieva; James A Swenberg
Molecular epidemiological studies in 1,3-butadiene exposed Czech workers: female-male comparisons.
Richard F Branda; J Patrick O'Neill; Elice Brooks; Cheryl Powden; Shelly J Naud; Janice A Nicklas
The effect of dietary folic acid deficiency on the cytotoxic and mutagenic responses to methyl methanesulfonate in wild-type and in 3-methyladenine DNA glycosylase-deficient Aag null mice.
Janice A Nicklas
Pseudogenes of the human HPRT1 gene.

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All Publications

2007: Richard J Albertini; Radim J Sram; Pamela M Vacek; Jeremiah Lynch; Pavel Rossner; Janice A Nicklas; Jake D McDonald; Gunnar Boysen; Nadia I Georgieva; James A Swenberg
Molecular epidemiological studies in 1,3-butadiene exposed Czech workers: female-male comparisons.
Chemico-biological interactions 2007;166(1-3):63-77.
2007: Richard F Branda; J Patrick O'Neill; Elice Brooks; Cheryl Powden; Shelly J Naud; Janice A Nicklas
The effect of dietary folic acid deficiency on the cytotoxic and mutagenic responses to methyl methanesulfonate in wild-type and in 3-methyladenine DNA glycosylase-deficient Aag null mice.
Mutation research 2007;615(1-2):12-7.
2006: Janice A Nicklas
Pseudogenes of the human HPRT1 gene.
Environmental and molecular mutagenesis 2006;47(3):212-8.
2005: Patrick O'Neill; Janice A Nicklas; Betsy Hirsch; Rick Jostes; Timothy Hunter; Linda Sullivan; Richard Albertini
In vitro studies of the genotoxicity of ionizing radiation in human G(0) T lymphocytes.
Environmental and molecular mutagenesis 2005;46(4):207-20.
2004: Janice A Nicklas; Elice Brooks; Timothy C Hunter; Richard M Single; Richard F Branda
Development of a quantitative PCR (TaqMan) assay for relative mitochondrial DNA copy number and the common mitochondrial DNA deletion in the rat.
Environmental and molecular mutagenesis 2004;44(4):313-20.
2003: Richard J Albertini; Radim J Srám; Pamela M Vacek; Jeremiah Lynch; Janice A Nicklas; Nico J van Sittert; Peter J Boogaard; Rogene F Henderson; James A Swenberg; Ad D Tates; Jonathan B Ward; Michael Wright; Marinel M Ammenheuser; Blanka Binkova; Walter B Blackwell; Franz A de Zwart; Dean Krako; Jennifer Krone; Hendricus Megens; Petra Musilová; Gabriela Rajská; Asoka Ranasinghe; Judah I Rosenblatt; Pavel Rössner; Jiri Rubes; Linda Sullivan; Patricia B Upton; Ailko H Zwinderman
Biomarkers in Czech workers exposed to 1,3-butadiene: a transitional epidemiologic study.
Research report (Health Effects Institute) 2003;(116):1-141; discussion 143-62.
2003: Terri Messier; J Patrick O'Neill; Sai-Mei Hou; Janice A Nicklas; Barry A Finette
In vivo transposition mediated by V(D)J recombinase in human T lymphocytes.
The EMBO journal 2003;22(6):1381-8.
2002: Richard F Branda; Elice Brooks; Zhuan Chen; Shelly J Naud; Scott A Mischler; Janice A Nicklas
Nucleic acid deletions and copy number in rats.
Comparative medicine 2002;52(4):359-62.
2002: Richard F Branda; Elice Brooks; Zhuan Chen; Shelly J Naud; Janice A Nicklas
Dietary modulation of mitochondrial DNA deletions and copy number after chemotherapy in rats.
Mutation research 2002;501(1-2):29-36.
2002: Scott W Ballinger; Stephen A Judice; Janice A Nicklas; Richard J Albertini; J Patrick O'Neill
DNA sequence analysis of interlocus recombination between the human T-cell receptor gamma variable (GV) and beta diversity-joining (BD/BJ) sequences on chromosome 7 (inversion 7).
Environmental and molecular mutagenesis 2002;40(2):85-92.
2002: M Williams; Irene R Rainville; Janice A Nicklas
Use of inverse PCR to amplify and sequence breakpoints of HPRT deletion and translocation mutations.
Environmental and molecular mutagenesis 2002;39(1):22-32.
2001: Richard J Albertini; Radim J Sram; Pamela M Vacek; J Lynch; M Wright; Janice A Nicklas; Peter J Boogaard; Rogene F Henderson; James A Swenberg; Ad D Tates; Jonathan B Ward
Biomarkers for assessing occupational exposures to 1,3-butadiene.
Chemico-biological interactions 2001;135-136():429-53.
2001: Elice Brooks; Richard F Branda; Janice A Nicklas; J Patrick O'Neill
Molecular description of three macro-deletions and an Alu-Alu recombination-mediated duplication in the HPRT gene in four patients with Lesch-Nyhan disease.
Mutation research 2001;476(1-2):43-54.
2001: Richard F Branda; J Patrick O'Neill; Elice Brooks; Lucy M Trombley; Janice A Nicklas
The effect of folate deficiency on the cytotoxic and mutagenic responses to ethyl methanesulfonate in human lymphoblastoid cell lines that differ in p53 status.
Mutation research 2001;473(1):51-71.
2001: A James Ruttenber; L T Harrison; A Baron; David McClure; Jason Glanz; R Quillin; J Patrick O'Neill; Linda Sullivan; J Campbell; Janice A Nicklas
hprt mutant frequencies, nonpulmonary malignancies, and domestic radon exposure: "postmortem" analysis of an interesting hypothesis.
Environmental and molecular mutagenesis 2001;37(1):7-16.
1999: B W Grant; Lucy M Trombley; Timothy C Hunter; Janice A Nicklas; J Patrick O'Neill; Richard J Albertini
HPRT mutations in vivo in human CD 34+ hematopoietic stem cells.
Mutation research 1999;431(2):183-98.
1999: P O'Neill; Lucy M Trombley; M Gundel; T Hunter; Janice A Nicklas; M L Ferreira; M J Bugallo; A C Farias; A Lohr; M Diamantopoulos; S Raskin
Identification of a new Lesch-Nyhan syndrome mutation (HPRTBrasil) and analysis of potentially heterozygous females.
Arquivos de neuro-psiquiatria 1999;57(4):907-11.
1999: Richard F Branda; AR Lafayette; J Patrick O'Neill; Janice A Nicklas
The effect of folate deficiency on the hprt mutational spectrum in Chinese hamster ovary cells treated with monofunctional alkylating agents.
Mutation research 1999;427(2):79-87.
1998: J Patrick O'Neill; P K Rogan; N Cariello; Janice A Nicklas
Mutations that alter RNA splicing of the human HPRT gene: a review of the spectrum.
Mutation research 1998;411(3):179-214.
1998: Bennett Van Houten; Y Chen; Janice A Nicklas; Irene R Rainville; J Patrick O'Neill
Development of long PCR techniques to analyze deletion mutations of the human hprt gene.
Mutation research 1998;403(1-2):171-5.
1998: Richard J Albertini; Janice A Nicklas; T R Skopek; L Recio; J Patrick O'Neill
Genetic instability in human T-lymphocytes.
Mutation research 1998;400(1-2):381-9.
1998: J M Pluth; J Patrick O'Neill; Janice A Nicklas; Richard J Albertini
Molecular bases of hprt mutations in malathion-treated human T-lymphocytes.
Mutation research 1998;397(2):137-48.
1998: Richard F Branda; Miles Hacker; AR Lafayette; E Nigels; Linda Sullivan; Janice A Nicklas; J Patrick O'Neill
Nutritional folate deficiency augments the in vivo mutagenic and lymphocytotoxic activities of alkylating agents.
Environmental and molecular mutagenesis 1998;32(1):33-8.
1997: L S Clark; Richard J Albertini; Janice A Nicklas
The aminothiol WR-1065 protects T lymphocytes from ionizing radiation-induced deletions of the HPRT gene.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1997;6(12):1033-7.
1997: Richard J Albertini; L S Clark; Janice A Nicklas; J Patrick O'Neill; T E Hui; Rick Jostes
Radiation quality affects the efficiency of induction and the molecular spectrum of HPRT mutations in human T cells.
Radiation research 1997;148(5 Suppl):S76-86.
1997: Richard F Branda; AR Lafayette; J Patrick O'Neill; Janice A Nicklas
Effect of folate deficiency on mutations at the hprt locus in Chinese hamster ovary cells exposed to monofunctional alkylating agents.
Cancer research 1997;57(13):2586-8.
1997: M J Lippert; Irene R Rainville; Janice A Nicklas; Richard J Albertini
Large deletions partially external to the human hprt gene result in chimeric transcripts.
Mutagenesis 1997;12(3):185-90.
1996: S W Ballinger; T G Bouder; G S Davis; S A Judice; Janice A Nicklas; Richard J Albertini
Mitochondrial genome damage associated with cigarette smoking.
Cancer research 1996;56(24):5692-7.
1996: L S Clark; Richard J Albertini; Janice A Nicklas
Hprt mutations in human T-lymphocytes reflect radioprotective effects of the aminothiol, WR-1065.
Carcinogenesis 1996;17(12):2647-53.
1996: J M Pluth; Janice A Nicklas; J Patrick O'Neill; Richard J Albertini
Increased frequency of specific genomic deletions resulting from in vitro malathion exposure.
Cancer research 1996;56(10):2393-9.
1996: Richard J Albertini; Janice A Nicklas; J Patrick O'Neill
Future research directions for evaluating human genetic and cancer risk from environmental exposures.
Environmental health perspectives 1996;104 Suppl 3():503-10.
1996: L S Clark; Janice A Nicklas
TCR beta PCR from crude preparations for restriction digest or sequencing.
Environmental and molecular mutagenesis 1996;27(1):34-8.
1995: Irene R Rainville; Richard J Albertini; Janice A Nicklas
Breakpoints and junctional regions of intragenic deletions in the HPRT gene in human T-Cells.
Somatic cell and molecular genetics 1995;21(5):309-26.
1995: S M Cooper; Karen Roessner; M Naito-Hoopes; C Dobbs; Janice A Nicklas; DB Howard; L K Gaur; Ralph C Budd
Unstimulated rheumatoid synovial T-cells have a consistent V beta gene bias when compared to peripheral blood T-cells.
Annals of the New York Academy of Sciences 1995;756():186-9.
1995: D K Manchester; Janice A Nicklas; J Patrick O'Neill; M J Lippert; S G Grant; Richard G Langlois; Dan H Moore; R H Jensen; Richard J Albertini; William L Bigbee
Sensitivity of somatic mutations in human umbilical cord blood to maternal environments.
Environmental and molecular mutagenesis 1995;26(3):203-12.
1995: M J Lippert; Janice A Nicklas; T C Hunter; Richard J Albertini
Pulsed field analysis of hprt T-cell large deletions: telomeric region breakpoint spectrum.
Mutation research 1995;326(1):51-64.
1995: M J Lippert; Richard J Albertini; Janice A Nicklas
Physical mapping of the human hprt chromosomal region (Xq26).
Mutation research 1995;326(1):39-49.
1994: J Patrick O'Neill; Janice A Nicklas; T C Hunter; O B Batson; M Allegretta; M T Falta; Richard F Branda; Richard J Albertini
The effect of T-lymphocyte 'clonality' on the calculated hprt mutation frequency occurring in vivo in humans.
Mutation research 1994;313(2-3):215-25.
1994: Barry A Finette; L M Sullivan; J Patrick O'Neill; Janice A Nicklas; Pamela M Vacek; Richard J Albertini
Determination of hprt mutant frequencies in T-lymphocytes from a healthy pediatric population: statistical comparison between newborn, children and adult mutant frequencies, cloning efficiency and age.
Mutation research 1994;308(2):223-31.
1993: Richard J Albertini; Janice A Nicklas; J Patrick O'Neill
Somatic cell gene mutations in humans: biomarkers for genotoxicity.
Environmental health perspectives 1993;101 Suppl 3():193-201.
1993: David Jacobson-Kram; Richard J Albertini; Richard F Branda; M T Falta; P T Iype; Ken Kolodner; S H Liou; Melissa A McDiarmid; M Morris; Janice A Nicklas
Measurement of chromosomal aberrations, sister chromatid exchange, hprt mutations, and DNA adducts in peripheral lymphocytes of human populations at increased risk for cancer.
Environmental health perspectives 1993;101 Suppl 3():121-5.
1993: Richard J Albertini; Janice A Nicklas; James C Fuscoe; Thomas R Skopek; Richard F Branda; J Patrick O'Neill
In vivo mutations in human blood cells: biomarkers for molecular epidemiology.
Environmental health perspectives 1993;99():135-41.
1993: Richard F Branda; L M Sullivan; J Patrick O'Neill; M T Falta; Janice A Nicklas; B Hirsch; Pamela M Vacek; Richard J Albertini
Measurement of HPRT mutant frequencies in T-lymphocytes from healthy human populations.
Mutation research 1993;285(2):267-79.
1992: James C Fuscoe; L J Zimmerman; Karen Harrington-Brock; L Burnette; Martha M Moore; Janice A Nicklas; J Patrick O'Neill; Richard J Albertini
V(D)J recombinase-mediated deletion of the hprt gene in T-lymphocytes from adult humans.
Mutation research 1992;283(1):13-20.
1991: James C Fuscoe; L J Zimmerman; M J Lippert; Janice A Nicklas; J Patrick O'Neill; Richard J Albertini
V(D)J recombinase-like activity mediates hprt gene deletion in human fetal T-lymphocytes.
Cancer research 1991;51(21):6001-5.
1991: Janice A Nicklas; J Patrick O'Neill; T C Hunter; M T Falta; M J Lippert; David Jacobson-Kram; J R Williams; Richard J Albertini
In vivo ionizing irradiations produce deletions in the hprt gene of human T-lymphocytes.
Mutation research 1991;250(1-2):383-96.
1991: Janice A Nicklas; T C Hunter; J Patrick O'Neill; Richard J Albertini
Fine structure mapping of the hypoxanthine-guanine phosphoribosyltransferase (HPRT) gene region of the human X chromosome (Xq26).
American journal of human genetics 1991;49(2):267-78.
1991: S M Cooper; D L Dier; Karen Roessner; Ralph C Budd; Janice A Nicklas
Diversity of rheumatoid synovial tissue T cells by T cell receptor analysis. Oligoclonal expansion in interleukin-2-responsive cells.
Arthritis and rheumatism 1991;34(5):537-46.
1991: J Patrick O'Neill; L M Sullivan; T C Hunter; Janice A Nicklas
Cytosine arabinoside enhancement of gamma irradiation induced mutations in human T-lymphocytes.
Environmental and molecular mutagenesis 1991;17(4):231-7.
1991: Janice A Nicklas; M J Lippert; T C Hunter; J Patrick O'Neill; Richard J Albertini
Analysis of human HPRT deletion mutations with X-linked probes and pulsed field gel electrophoresis.
Environmental and molecular mutagenesis 1991;18(4):270-3.
1990: Janice A Nicklas; M T Falta; T C Hunter; J Patrick O'Neill; David Jacobson-Kram; J R Williams; Richard J Albertini
Molecular analysis of in vivo hprt mutations in human T lymphocytes. V. Effects of total body irradiation secondary to radioimmunoglobulin therapy (RIT)
Mutagenesis 1990;5(5):461-8.
1990: Thomas R Skopek; Leslie Recio; D Simpson; Louis Dallaire; S B Melancon; H Ogier; J Patrick O'Neill; M T Falta; Janice A Nicklas; Richard J Albertini
Molecular analyses of a Lesch-Nyhan syndrome mutation (hprtMontreal) by use of T-lymphocyte cultures.
Human genetics 1990;85(1):111-6.
1990: M Allegretta; Janice A Nicklas; Subramaniam Sriram; Richard J Albertini
T cells responsive to myelin basic protein in patients with multiple sclerosis.
Science (New York, N.Y.) 1990;247(4943):718-21.
1990: J Patrick O'Neill; T C Hunter; L M Sullivan; Janice A Nicklas; Richard J Albertini
Southern-blot analyses of human T-lymphocyte mutants induced in vitro by gamma-irradiation.
Mutation research 1990;240(2):143-9.
1990: Richard J Albertini; Janice A Nicklas; J Patrick O'Neill
Studies of DNA alterations in in vivo somatic cell mutations in humans.
Basic life sciences 1990;53():315-28.
1990: Richard J Albertini; J Patrick O'Neill; Janice A Nicklas; Leslie Recio; Thomas R Skopek
hprt mutations in vivo in human T-lymphocytes: frequencies, spectra and clonality.
Progress in clinical and biological research 1990;340C():15-24.
1990: Richard J Albertini; Janice A Nicklas; J Patrick O'Neill; S H Robison
In vivo somatic mutations in humans: measurement and analysis.
Annual review of genetics 1990;24():305-26.
1989: Janice A Nicklas; T C Hunter; J Patrick O'Neill; Richard J Albertini
Molecular analyses of in vivo hprt mutations in human T-lymphocytes. III. Longitudinal study of hprt gene structural alterations and T-cell clonal origins.
Mutation research 1989;215(2):147-60.
1989: M J McGinniss; Janice A Nicklas; Richard J Albertini
Molecular analyses of in vivo hprt mutations in human T-lymphocytes: IV. Studies in newborns.
Environmental and molecular mutagenesis 1989;14(4):229-37.
1988: Janice A Nicklas; J Patrick O'Neill; L M Sullivan; T C Hunter; M Allegretta; B F Chastenay; B L Libbus; Richard J Albertini
Molecular analyses of in vivo hypoxanthine-guanine phosphoribosyltransferase mutations in human T-lymphocytes: II. Demonstration of a clonal amplification of hprt mutant T-lymphocytes in vivo.
Environmental and molecular mutagenesis 1988;12(3):271-84.
1987: Janice A Nicklas; T C Hunter; L M Sullivan; J K Berman; J Patrick O'Neill; Richard J Albertini
Molecular analyses of in vivo hprt mutations in human T-lymphocytes. I. Studies of low frequency 'spontaneous' mutants by Southern blots.
Mutagenesis 1987;2(5):341-7.
1987: J Patrick O'Neill; M J McGinniss; J K Berman; L M Sullivan; Janice A Nicklas; Richard J Albertini
Refinement of a T-lymphocyte cloning assay to quantify the in vivo thioguanine-resistant mutant frequency in humans.
Mutagenesis 1987;2(2):87-94.