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Brian Nickoloff

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Shilpa Keerthivasan; Rebecca Lawlor; I Caroline Le Poole; Lucio Miele; Lisa Minter; Brian J Nickoloff; Juan Anguita; Tonya Bates; Ignacio Juncadella; Justine Roderick; Reem Suleiman; Barbara A Osborne
Notch signaling regulates mouse and human Th17 differentiation.
Jian-Zhong Qin; H Xin; Brian J Nickoloff
2-deoxyglucose sensitizes melanoma cells to TRAIL-induced apoptosis which is reduced by mannose.
Aleksandar Sekulic; Su Y Kim; Galen Hostetter; Stephanie Savage; Janine G Einspahr; Anil Prasad; Paul Sagerman; Clara Curiel-Lewandrowski; Robert Krouse; George Bowden; James Warneke; David S Alberts; Mark R Pittelkow; David DiCaudo; Brian J Nickoloff; Jeffrey M. Trent; Michael Bittner
Loss of inositol polyphosphate 5-phosphatase is an early event in development of cutaneous squamous cell carcinoma.

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All Publications

2011: Shilpa Keerthivasan; Rebecca Lawlor; I Caroline Le Poole; Lucio Miele; Lisa Minter; Brian J Nickoloff; Juan Anguita; Tonya Bates; Ignacio Juncadella; Justine Roderick; Reem Suleiman; Barbara A Osborne
Notch signaling regulates mouse and human Th17 differentiation.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(2):692-701.
2010: Jian-Zhong Qin; H Xin; Brian J Nickoloff
2-deoxyglucose sensitizes melanoma cells to TRAIL-induced apoptosis which is reduced by mannose.
Biochemical and biophysical research communications 2010;401(2):293-9.
2010: Aleksandar Sekulic; Su Y Kim; Galen Hostetter; Stephanie Savage; Janine G Einspahr; Anil Prasad; Paul Sagerman; Clara Curiel-Lewandrowski; Robert Krouse; George Bowden; James Warneke; David S Alberts; Mark R Pittelkow; David DiCaudo; Brian J Nickoloff; Jeffrey M. Trent; Michael Bittner
Loss of inositol polyphosphate 5-phosphatase is an early event in development of cutaneous squamous cell carcinoma.
Cancer prevention research (Philadelphia, Pa.) 2010;3(10):1277-83.
2010: Jian-Zhong Qin; H Xin; Brian J Nickoloff
Targeting glutamine metabolism sensitizes melanoma cells to TRAIL-induced death.
Biochemical and biophysical research communications 2010;398(1):146-52.
2010: Steven P Stratton; David S Alberts; Janine G Einspahr; Paul M Sagerman; James Warneke; Clara Curiel-Lewandrowski; Paul B Myrdal; Kelly L Karlage; Brian J Nickoloff; Chris Brooks; Kathylynn Saboda; Michael Yozwiak; Mary F Krutzsch; Chengcheng Hu; Maria Lluria-Prevatt; Zigang Dong; George Bowden; Peter H Bartels
A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer.
Cancer prevention research (Philadelphia, Pa.) 2010;3(2):160-9.
2009: Urszula A Sobol; Karen L Sherman; Jason Smith; Suneel N Nagda; Kenneth Micetich; Brian J Nickoloff; Margo Shoup
Sweet's syndrome with neurologic manifestations in a patient with esophageal adenocarcinoma: case report and review of the literature.
International journal of dermatology 2009;48(10):1062-5.
2008: Brian J Nickoloff
Saving the skin from drug-induced detachment.
Nature medicine 2008;14(12):1311-3.
2008: Guang Yang; Yitang Li; Emi K Nishimura; Hong Xin; Anyu Zhou; Yinshi Guo; Liang Dong; Mitchell F Denning; Brian J Nickoloff; Rutao Cui
Inhibition of PAX3 by TGF-beta modulates melanocyte viability.
Molecular cell 2008;32(4):554-63.
2008: Barbara Bedogni; James A Warneke; Brian J Nickoloff; Amato J Giaccia; Marianne Powell
Notch1 is an effector of Akt and hypoxia in melanoma development.
The Journal of clinical investigation 2008;118(11):3660-70.
2008: L L Song; Y Peng; J Yun; Paola Rizzo; Vijaya Chaturvedi; Sanne Weijzen; W Martin Kast; P J B Stone; L Santos; A Loredo; Urban Lendahl; G Sonenshein; Barbara A Osborne; Jian-Zhong Qin; A Pannuti; Brian J Nickoloff; Lucio Miele
Notch-1 associates with IKKalpha and regulates IKK activity in cervical cancer cells.
Oncogene 2008;27(44):5833-44.
2008: Paola Rizzo; Haixi Miao; Gwendolyn D'Souza; Clodia Osipo; Lynda L Song; Jieun Yun; Huiping Zhao; Joaquina Mascarenhas; Debra Wyatt; Giovanni Antico; Lu Hao; Katharine Yao; Prabha B Rajan; Chindo Hicks; Kalliopi Siziopikou; Suzanne Selvaggi; Amina Bashir; Deepali Bhandari; Adriano Marchese; Urban Lendahl; Jian-Zhong Qin; Debra A Tonetti; Kathy S Albain; Brian J Nickoloff; Lucio Miele
Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches.
Cancer research 2008;68(13):5226-35.
2008: Kevin D Cooper; Richard D Sontheimer; Jan Dutz; Sam T Hwang; Brian J Nickoloff; Shinji Shimada; Molly Kulesz-Martin; Jackie R Bickenbach
56th annual Montagna Symposium on the Biology of Skin: Epidermal T-cell interactions--clinicopathological and basic mechanisms.
The Journal of investigative dermatology 2008;128(6):1351-3.
2008: Christine M Gresik; Luke P Brewster; Gerard Abood; Kathy G Supple; Geoffrey M Silver; Richard L Gamelli; Brian J Nickoloff
Ecthyma gangrenosum following toxic epidermal necrolysis syndrome in a 3-year-old boy-a survivable series of events.
Journal of burn care & research : official publication of the American Burn Association 2008;29(3):555-8.
2008: Taisuke Ito; Natsuho Ito; Matthias Saatoff; Hideo Hashizume; Hidekazu Fukamizu; Brian J Nickoloff; Masahiro Takigawa; Ralf Paus
Maintenance of hair follicle immune privilege is linked to prevention of NK cell attack.
The Journal of investigative dermatology 2008;128(5):1196-206.
2008: Janine G Einspahr; George Bowden; David S Alberts; Naja McKenzie; Kathylynn Saboda; James Warneke; Stuart Salasche; James Ranger-Moore; Clara Curiel-Lewandrowski; Raymond B Nagle; Brian J Nickoloff; Chris Brooks; Zigang Dong; Steven P Stratton
Cross-validation of murine UV signal transduction pathways in human skin.
Photochemistry and photobiology 2008;84(2):463-76.
2008: Brian J Nickoloff
Immunobiology of acute cytotoxic drug reactions.
Current directions in autoimmunity 2008;10():53-64.
2008: Gerard J Abood; Brian J Nickoloff; Richard L Gamelli
Treatment strategies in toxic epidermal necrolysis syndrome: where are we at?
Journal of burn care & research : official publication of the American Burn Association 2008;29(1):269-76.
2007: Brian J Nickoloff; Hong Xin; Frank O Nestle; Jian-Zhong Qin
The cytokine and chemokine network in psoriasis.
Clinics in dermatology 2007;25(6):568-73.
2007: Deborah J Marble; Kenneth B Gordon; Brian J Nickoloff
Targeting TNFalpha rapidly reduces density of dendritic cells and macrophages in psoriatic plaques with restoration of epidermal keratinocyte differentiation.
Journal of dermatological science 2007;48(2):87-101.
2007: Brian J Nickoloff; Jian-Zhong Qin; Frank O Nestle
Immunopathogenesis of psoriasis.
Clinical reviews in allergy & immunology 2007;33(1-2):45-56.
2007: Amir Toor; Patrick J Stiff; Brian J Nickoloff; Tulio Rodriguez; Jared L Klein; Kenneth B Gordon
Alefacept in corticosteroid refractory graft versus host disease: early results indicate promising activity.
The Journal of dermatological treatment 2007;18(1):13-8.
2006: Jian-Zhong Qin; Hong Xin; Leonid A Sitailo; Mitchell F Denning; Brian J Nickoloff
Enhanced killing of melanoma cells by simultaneously targeting Mcl-1 and NOXA.
Cancer research 2006;66(19):9636-45.
2006: Brian J Nickoloff; Brian Bonish; Deborah J Marble; Kellean A Schriedel; Luisa A DiPietro; Kenneth B Gordon; Mark W Lingen
Lessons learned from psoriatic plaques concerning mechanisms of tissue repair, remodeling, and inflammation.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2006;11(1):16-29.
2006: Jolanta M Topczewska; Lynne-Marie Postovit; Naira V Margaryan; Anthony Sam; Angela R Hess; William W Wheaton; Brian J Nickoloff; Jacek Topczewski; Mary J C Hendrix
Embryonic and tumorigenic pathways converge via Nodal signaling: role in melanoma aggressiveness.
Nature medicine 2006;12(8):925-32.
2006: Christine L Curry; Laura L Reed; Brian J Nickoloff; Lucio Miele; Kimberly E Foreman
Notch-independent regulation of Hes-1 expression by c-Jun N-terminal kinase signaling in human endothelial cells.
Laboratory investigation; a journal of technical methods and pathology 2006;86(8):842-52.
2006: Lucio Miele; H Miao; Brian J Nickoloff
NOTCH signaling as a novel cancer therapeutic target.
Current cancer drug targets 2006;6(4):313-23.
2006: Brian J Nickoloff
Keratinocytes regain momentum as instigators of cutaneous inflammation.
Trends in molecular medicine 2006;12(3):102-6.
2006: Anisha D'Costa; J K Robinson; Tazeen Maududi; Vijaya Chaturvedi; Brian J Nickoloff; Mitchell F Denning
The proapoptotic tumor suppressor protein kinase C-delta is lost in human squamous cell carcinomas.
Oncogene 2006;25(3):378-86.
2006: Vijaya Chaturvedi; Leonid A Sitailo; Barbara Bodner; Mitchell F Denning; Brian J Nickoloff
Defining the caspase-containing apoptotic machinery contributing to cornification in human epidermal equivalents.
Experimental dermatology 2006;15(1):14-22.
2006: Vijaya Chaturvedi; Barbara Bodner; Jian-Zhong Qin; Brian J Nickoloff
Knock down of p53 levels in human keratinocytes increases susceptibility to type I and type II interferon-induced apoptosis mediated by a TRAIL dependent pathway.
Journal of dermatological science 2006;41(1):31-41.
2005: Elisabeth A Seftor; Kevin Brown; Lynda Chin; Dawn A Kirschmann; William W Wheaton; Alexei Protopopov; Bin Feng; yoganand balagurunathan; Jeffrey M. Trent; Brian J Nickoloff; Richard E B Seftor; Mary J C Hendrix
Epigenetic transdifferentiation of normal melanocytes by a metastatic melanoma microenvironment.
Cancer research 2005;65(22):10164-9.
2005: Brian J Nickoloff; Mary J C Hendrix; Pam Pollock; Jeffrey M. Trent; Lucio Miele; Jian-Zhong Qin
Notch and NOXA-related pathways in melanoma cells.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2005;10(2):95-104.
2005: Angela R Hess; Lynne-Marie Postovit; Naira V Margaryan; Elisabeth A Seftor; Galen B Schneider; Richard E B Seftor; Brian J Nickoloff; Mary J C Hendrix
Focal adhesion kinase promotes the aggressive melanoma phenotype.
Cancer research 2005;65(21):9851-60.
2005: Kenneth B Gordon; Brian Bonish; T Patel; Craig L Leonardi; Brian J Nickoloff
The tumour necrosis factor-alpha inhibitor adalimumab rapidly reverses the decrease in epidermal Langerhans cell density in psoriatic plaques.
The British journal of dermatology 2005;153(5):945-53.
2005: Christine L Curry; Laura L Reed; todd golde; Lucio Miele; Brian J Nickoloff; Kimberly E Foreman
Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells.
Oncogene 2005;24(42):6333-44.
2005: Vijaya Chaturvedi; Leonid A Sitailo; Jian-Zhong Qin; Barbara Bodner; Mitchell F Denning; Jonathan Curry; Wengeng Zhang; Douglas Brash; Brian J Nickoloff
Knockdown of p53 levels in human keratinocytes accelerates Mcl-1 and Bcl-x(L) reduction thereby enhancing UV-light induced apoptosis.
Oncogene 2005;24(34):5299-312.
2005: Jian-Zhong Qin; Jeffrey Ziffra; Lawrence S Stennett; Barbara Bodner; Brian Bonish; Vijaya Chaturvedi; Frank Bennett; Pam Pollock; Jeffrey M. Trent; Mary J C Hendrix; Paola Rizzo; Lucio Miele; Brian J Nickoloff
Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cells.
Cancer research 2005;65(14):6282-93.
2005: Adam M Quinn; Kimberly Brown; Brian Bonish; Jonathan Curry; Kenneth B Gordon; James Sinacore; Richard L Gamelli; Brian J Nickoloff
Uncovering histologic criteria with prognostic significance in toxic epidermal necrolysis.
Archives of dermatology 2005;141(6):683-7.
2005: Tara M Kroll; Hemamalini Bommiasamy; Raymond E Boissy; Claudia Hernandez; Brian J Nickoloff; Ruben Mestril; I Caroline Le Poole
4-Tertiary butyl phenol exposure sensitizes human melanocytes to dendritic cell-mediated killing: relevance to vitiligo.
The Journal of investigative dermatology 2005;124(4):798-806.
2005: Patricia Bacon; Barbara Bodner; Brian J Nickoloff
Senescent human keratinocytes suppress colony formation of HeLa cells.
Journal of dermatological science 2005;38(1):64-6.
2005: W-H Boehncke; M P Schön; Giampiero Girolomoni; G Giromolomi; Christopher E M Griffiths; J D Bos; K Thestrup-Pedersen; A Cavani; F Nestle; Brian Bonish; J J Campbell; C Brakebusch; Brian J Nickoloff
Leukocyte extravasation as a target for anti-inflammatory therapy - Which molecule to choose?
Experimental dermatology 2005;14(1):70-80.
2004: Vijaya Chaturvedi; Patricia Bacon; Barbara Bodner; Brian J Nickoloff
Proliferating cultured human keratinocytes are more susceptible to apoptosis compared with mouse keratinocytes.
The Journal of investigative dermatology 2004;123(6):1200-3.
2004: Lawrence S Stennett; Adam I Riker; Tara M Kroll; Janine ChaMberlin; Toru Miki; Brian J Nickoloff; I Caroline Le Poole
Expression of gp100 and CDK2 in melanoma cells is not co-regulated by a shared promoter region.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2004;17(5):525-32.
2004: Jian-Zhong Qin; Lawrence S Stennett; Patricia Bacon; Barbara Bodner; Mary J C Hendrix; Richard E B Seftor; Elisabeth A Seftor; Naira V Margaryan; Pam Pollock; Amy Curtis; Jeffrey M. Trent; Frank Bennett; Lucio Miele; Brian J Nickoloff
p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas.
Molecular cancer therapeutics 2004;3(8):895-902.
2004: Jian-Zhong Qin; Patricia Bacon; Jeffrey Panella; Leonid A Sitailo; Mitchell F Denning; Brian J Nickoloff
Low-dose UV-radiation sensitizes keratinocytes to TRAIL-induced apoptosis.
Journal of cellular physiology 2004;200(1):155-66.
2004: Brian J Nickoloff; Frank O Nestle
Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities.
The Journal of clinical investigation 2004;113(12):1664-75.
2004: Mei-Shiang Jang; Haixi Miao; Nadia Carlesso; Leslie Shelly; Andrei Zlobin; Nicole Darack; Jian-Zhong Qin; Brian J Nickoloff; Lucio Miele
Notch-1 regulates cell death independently of differentiation in murine erythroleukemia cells through multiple apoptosis and cell cycle pathways.
Journal of cellular physiology 2004;199(3):418-33.
2004: Brian J Nickoloff; Mark W Lingen; Bey-Dih Chang; Mei Shen; Mari Swift; Jonathan Curry; Patricia Bacon; Barbara Bodner; Igor B Roninson
Tumor suppressor maspin is up-regulated during keratinocyte senescence, exerting a paracrine antiangiogenic activity.
Cancer research 2004;64(9):2956-61.
2004: I Caroline Le Poole; Anna Wañkowicz-Kaliñska; René M J G J van den Wijngaard; Brian J Nickoloff; Pranab K Das
Autoimmune aspects of depigmentation in vitiligo.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2004;9(1):68-72.
2004: June K Robinson; Brian J Nickoloff
Digital epiluminescence microscopy monitoring of high-risk patients.
Archives of dermatology 2004;140(1):49-56.
2004: Vijaya Chaturvedi; Jian-Zhong Qin; Lawrence S Stennett; Divaker Choubey; Brian J Nickoloff
Resistance to UV-induced apoptosis in human keratinocytes during accelerated senescence is associated with functional inactivation of p53.
Journal of cellular physiology 2004;198(1):100-9.
2003: I Caroline Le Poole; Lawrence S Stennett; Brian Bonish; L Dee; J K Robinson; Claudia Hernandez; S K Hann; Brian J Nickoloff
Expansion of vitiligo lesions is associated with reduced epidermal CDw60 expression and increased expression of HLA-DR in perilesional skin.
The British journal of dermatology 2003;149(4):739-48.
2003: Brian J Nickoloff; Barbara A Osborne; Lucio Miele
Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents.
Oncogene 2003;22(42):6598-608.
2003: Hong Xin; Jonathan Curry; Ricky Johnstone; Brian J Nickoloff; Divaker Choubey
Role of IFI 16, a member of the interferon-inducible p200-protein family, in prostate epithelial cellular senescence.
Oncogene 2003;22(31):4831-40.
2003: Vijaya Chaturvedi; Brian Bonish; Patricia Bacon; Jian-Zhong Qin; Mitchell F Denning; Kimberly E Foreman; Manuel O Diaz; June Robinson; Brian J Nickoloff
Role for Id-1 in immunobiology of normal keratinocytes and in basal cell carcinoma.
Experimental dermatology 2003;12(3):255-60.
2003: Jonathan L Curry; Jian-Zhong Qin; June Robinson; Brian J Nickoloff
Reactivity of resident immunocytes in normal and prepsoriatic skin using an ex vivo skin-explant model system.
Archives of pathology & laboratory medicine 2003;127(3):289-96.
2003: Jonathan L Curry; Jian-Zhong Qin; Brian Bonish; Ryan Carrick; Patricia Bacon; Jeffrey Panella; June Robinson; Brian J Nickoloff
Innate immune-related receptors in normal and psoriatic skin.
Archives of pathology & laboratory medicine 2003;127(2):178-86.
2003: Vijaya Chaturvedi; Mirjana Cesnjaj; Patricia Bacon; Jeffrey Panella; Divaker Choubey; Manuel O Diaz; Brian J Nickoloff
Role of INK4a/Arf locus-encoded senescent checkpoints activated in normal and psoriatic keratinocytes.
The American journal of pathology 2003;162(1):161-70.
2002: Brian J Nickoloff; Jian-Zhong Qin; Vijava Chaturvedi; Patricia Bacon; Jeffrey Panella; Mitchell F Denning
Life and death signaling pathways contributing to skin cancer.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2002;7(1):27-35.
2002: Jian-Zhong Qin; Patricia Bacon; Vijaya Chaturvedi; Brian Bonish; Brian J Nickoloff
Pathways involved in proliferating, senescent and immortalized keratinocyte cell death mediated by two different TRAIL preparations.
Experimental dermatology 2002;11(6):573-83.
2002: Sanne Weijzen; Markwin P Velders; Amira G Elmishad; Patricia Bacon; Jeffrey R Panella; Brian J Nickoloff; Lucio Miele; W Martin Kast
The Notch ligand Jagged-1 is able to induce maturation of monocyte-derived human dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(8):4273-8.
2002: Brian J Nickoloff
Cutaneous dendritic cells in the crossfire between innate and adaptive immunity.
Journal of dermatological science 2002;29(3):159-65.
2002: Jun Tang; Gabriel M Gordon; Brian J Nickoloff; Kimberly E Foreman
The helix-loop-helix protein id-1 delays onset of replicative senescence in human endothelial cells.
Laboratory investigation; a journal of technical methods and pathology 2002;82(8):1073-9.
2002: Chun Lu; Gabriel M Gordon; bala chandran; Brian J Nickoloff; Kimberly E Foreman
Human herpesvirus 8 reactivation and human immunodeficiency virus type 1 gp120.
Archives of pathology & laboratory medicine 2002;126(8):941-6.
2002: Brian J Nickoloff; Jian-Zhong Qin; Vijaya Chaturvedi; Mitchell F Denning; Brian Bonish; Lucio Miele
Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgamma.
Cell death and differentiation 2002;9(8):842-55.
2002: Jian-Zhong Qin; Vijaya Chaturvedi; Mitchell F Denning; Patricia Bacon; Jeffrey Panella; Divaker Choubey; Brian J Nickoloff
Regulation of apoptosis by p53 in UV-irradiated human epidermis, psoriatic plaques and senescent keratinocytes.
Oncogene 2002;21(19):2991-3002.
2002: Alfred E Chang; Bruce G Redman; Joel R Whitfield; Brian J Nickoloff; Thomas M Braun; Peter P Lee; James Geiger; James J Mulé
A phase I trial of tumor lysate-pulsed dendritic cells in the treatment of advanced cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(4):1021-32.
2002: Vijaya Chaturvedi; Sue Chu MD; Mathew Carrol BS; Jennifer W Brenner BS; Brian J Nickoloff
Estimation of size of clonal unit for keratinocytes in normal human skin.
Archives of pathology & laboratory medicine 2002;126(4):420-4.
2002: I Caroline Le Poole; Adam I Riker; M Eugenia Quevedo; Lawrence S Stennett; Ena Wang; Francesco M Marincola; W Martin Kast; June K Robinson; Brian J Nickoloff
Interferon-gamma reduces melanosomal antigen expression and recognition of melanoma cells by cytotoxic T cells.
The American journal of pathology 2002;160(2):521-8.
2002: Brian J Nickoloff; Kimberly E Foreman
Etiology and pathogenesis of Kaposi's sarcoma.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2002;160():332-42.
2002: Mitchell F Denning; Yihua Wang; Shalini S Tibudan; Serhan Alkan; Brian J Nickoloff; Jian-Zhong Qin
Caspase activation and disruption of mitochondrial membrane potential during UV radiation-induced apoptosis of human keratinocytes requires activation of protein kinase C.
Cell death and differentiation 2002;9(1):40-52.
2001: Jian-Zhong Qin; Patricia Bacon; V Chaturvedi; Brian J Nickoloff
Role of NF-kappaB activity in apoptotic response of keratinocytes mediated by interferon-gamma, tumor necrosis factor-alpha, and tumor-necrosis-factor-related apoptosis-inducing ligand.
The Journal of investigative dermatology 2001;117(4):898-907.
2001: Raj S Mitra; MA Benedict; D Qian; Kimberly E Foreman; D Ekhterae; Brian J Nickoloff; Gabriel Nuñez
Killing of sarcoma cells by proapoptotic Bcl-X(S): role of the BH3 domain and regulation by Bcl-X(L).
Neoplasia (New York, N.Y.) 2001;3(5):437-45.
2001: Kimberly E Foreman; Jacques Friborg; bala chandran; H Katano; T Sata; M Mercader; Gary Nabel; Brian J Nickoloff
Injection of human herpesvirus-8 in human skin engrafted on SCID mice induces Kaposi's sarcoma-like lesions.
Journal of dermatological science 2001;26(3):182-93.
2001: M Mercader; Brian J Nickoloff; Kimberly E Foreman
Induction of human immunodeficiency virus 1 replication by human herpesvirus 8.
Archives of pathology & laboratory medicine 2001;125(6):785-9.
2001: Vijaya Chaturvedi; Jian-Zhong Qin; Mitchell F Denning; Divaker Choubey; Manuel O Diaz; Brian J Nickoloff
Abnormal NF-kappaB signaling pathway with enhanced susceptibility to apoptosis in immortalized keratinocytes.
Journal of dermatological science 2001;26(1):67-78.
2001: Diane M Da Silva; Markwin P Velders; JD Nieland; John T Schiller; Brian J Nickoloff; W Martin Kast
Physical interaction of human papillomavirus virus-like particles with immune cells.
International immunology 2001;13(5):633-41.
2001: CJ Kirk; Dennis Hartigan-O'Connor; Brian J Nickoloff; Jeffrey S Chamberlain; M Giedlin; L Aukerman; J J Mule
T cell-dependent antitumor immunity mediated by secondary lymphoid tissue chemokine: augmentation of dendritic cell-based immunotherapy.
Cancer research 2001;61(5):2062-70.
2001: Baibiao Huang; Brian Bonish; Vijaya Chaturvedi; Jian-Zhong Qin; Brian J Nickoloff
Keratinocyte CDw60 expression is modulated by both a Th-1 type cytokine IFN-gamma and Th-2 cytokines IL-4 and IL-13: relevance to psoriasis.
The Journal of investigative dermatology 2001;116(2):305-12.
2001: H H Amin; guy petruzzelli; Aliya N Husain; Brian J Nickoloff
Primary malignant melanoma of the larynx.
Archives of pathology & laboratory medicine 2001;125(2):271-3.
2001: Kimberly A Candido; K Shimizu; Julie C McLaughlin; Robin Kunkel; Jennifer A Fuller; Bruce G Redman; EK Thomas; Brian J Nickoloff; James J Mulé
Local administration of dendritic cells inhibits established breast tumor growth: implications for apoptosis-inducing agents.
Cancer research 2001;61(1):228-36.
2000: Brian J Nickoloff
Characterization of lymphocyte-dependent angiogenesis using a SCID mouse: human skin model of psoriasis.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2000;5(1):67-73.
2000: Brian J Nickoloff; Brian Bonish; Baibiao Huang; Steven A Porcelli
Characterization of a T cell line bearing natural killer receptors and capable of creating psoriasis in a SCID mouse model system.
Journal of dermatological science 2000;24(3):212-25.
2000: Brian Bonish; D Jullien; Y Dutronc; Baibiao Huang; R Modlin; F M Spada; Steven A Porcelli; Brian J Nickoloff
Overexpression of CD1d by keratinocytes in psoriasis and CD1d-dependent IFN-gamma production by NK-T cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(7):4076-85.
2000: Brian J Nickoloff; Jens Schröder; P von den Driesch; S P Raychaudhuri; E M Farber; W H Boehncke; V B Morhenn; E W Rosenberg; M P Schön; M F Holick
Is psoriasis a T-cell disease?
Experimental dermatology 2000;9(5):359-75.
2000: Brian J Nickoloff; Vijaya Chaturvedi; Patricia Bacon; Jian-Zhong Qin; Mitchell F Denning; Manuel O Diaz
Id-1 delays senescence but does not immortalize keratinocytes.
The Journal of biological chemistry 2000;275(36):27501-4.
2000: M Mercader; B Taddeo; Jeffrey Panella; bala chandran; Brian J Nickoloff; Kimberly E Foreman
Induction of HHV-8 lytic cycle replication by inflammatory cytokines produced by HIV-1-infected T cells.
The American journal of pathology 2000;156(6):1961-71.
2000: Alfred E Chang; Qiao Li; D Keith Bishop; Daniel Normolle; Bruce G Redman; Brian J Nickoloff
Immunogenetic therapy of human melanoma utilizing autologous tumor cells transduced to secrete granulocyte-macrophage colony-stimulating factor.
Human gene therapy 2000;11(6):839-50.
2000: Keishi Tanigawa; H Yu; R Sun; Brian J Nickoloff; Alfred E Chang
Gene gun application in the generation of effector T cells for adoptive immunotherapy.
Cancer immunology, immunotherapy : CII 2000;48(11):635-43.
2000: B Taddeo; Brian J Nickoloff; Kimberly E Foreman
Caspase inhibitor blocks human immunodeficiency virus 1-induced T-cell death without enhancement of HIV-1 replication and dimethyl sulfoxide increases HIV-1 replication without influencing T-cell survival.
Archives of pathology & laboratory medicine 2000;124(2):240-5.
1999: Jian-Zhong Qin; Vijaya Chaturvedi; Mitchell F Denning; Divaker Choubey; Manuel O Diaz; Brian J Nickoloff
Role of NF-kappaB in the apoptotic-resistant phenotype of keratinocytes.
The Journal of biological chemistry 1999;274(53):37957-64.
1999: Michael Hottiger; T N Dam; Brian J Nickoloff; Timothy R B Johnson; Gary Nabel
Liposome-mediated gene transfer into human basal cell carcinoma.
Gene therapy 1999;6(12):1929-35.
1999: T N Dam; Sewon Kang; Brian J Nickoloff; John J Voorhees
1alpha,25-dihydroxycholecalciferol and cyclosporine suppress induction and promote resolution of psoriasis in human skin grafts transplanted on to SCID mice.
The Journal of investigative dermatology 1999;113(6):1082-9.
1999: Andrzej Slominski; Jacobo Wortsman; A Carlson; M Mihm; Brian J Nickoloff; Kenneth D McClatchey
Molecular pathology of soft tissue and bone tumors. A review.
Archives of pathology & laboratory medicine 1999;123(12):1246-59.
1999: Brian J Nickoloff
Skin innate immune system in psoriasis: friend or foe?
The Journal of clinical investigation 1999;104(9):1161-4.
1999: Brian J Nickoloff
The immunologic and genetic basis of psoriasis.
Archives of dermatology 1999;135(9):1104-10.
1999: Vijaya Chaturvedi; Jian-Zhong Qin; Mitchell F Denning; Divaker Choubey; Manuel O Diaz; Brian J Nickoloff
Apoptosis in proliferating, senescent, and immortalized keratinocytes.
The Journal of biological chemistry 1999;274(33):23358-67.
1999: Brian J Nickoloff; T Wrone-Smith
Injection of pre-psoriatic skin with CD4+ T cells induces psoriasis.
The American journal of pathology 1999;155(1):145-58.
1999: Kimberly E Foreman; T Wrone-Smith; A E Krueger; Brian J Nickoloff
Expression of costimulatory molecules CD80 and/or CD86 by a Kaposi's sarcoma tumor cell line induces differential T-cell activation and proliferation.
Clinical immunology (Orlando, Fla.) 1999;91(3):345-53.
1999: Brian J Nickoloff; T Wrone-Smith; Brian Bonish; Steven A Porcelli
Response of murine and normal human skin to injection of allogeneic blood-derived psoriatic immunocytes: detection of T cells expressing receptors typically present on natural killer cells, including CD94, CD158, and CD161.
Archives of dermatology 1999;135(5):546-52.
1999: T Wrone-Smith; J Bergstrom; M Eugenia Quevedo; V Reddy; C Gutierrez-Steil; Brian J Nickoloff
Differential expression of cell survival and cell cycle regulatory proteins in cutaneous squamoproliferative lesions.
Journal of dermatological science 1999;19(1):53-67.
1998: Brian J Nickoloff
Pathogenesis and immunointervention strategies for psoriasis. IBC's Inflammatory Skin Disorders. Washington, DC, USA. September 17-18, 1998.
Molecular medicine today 1998;4(12):512-3.
1998: Andrzej Slominski; Jacobo Wortsman; Brian J Nickoloff; Kenneth D McClatchey; M C Mihm; J S Ross
Molecular pathology of malignant melanoma.
American journal of clinical pathology 1998;110(6):788-94.
1998: Jacques Friborg; Wing-Pui Kong; CC Flowers; S L Flowers; Y Sun; Kimberly E Foreman; Brian J Nickoloff; Gary Nabel
Distinct biology of Kaposi's sarcoma-associated herpesvirus from primary lesions and body cavity lymphomas.
Journal of virology 1998;72(12):10073-82.
1998: Mitchell F Denning; Yihua Wang; Brian J Nickoloff; T Wrone-Smith
Protein kinase Cdelta is activated by caspase-dependent proteolysis during ultraviolet radiation-induced apoptosis of human keratinocytes.
The Journal of biological chemistry 1998;273(45):29995-30002.
1998: Kimberly E Foreman; Serhan Alkan; A E Krueger; Jeffrey Panella; LJ Swinnen; Brian J Nickoloff
Geographically distinct HHV-8 DNA sequences in Saudi Arabian Iatrogenic Kaposi's sarcoma lesions.
The American journal of pathology 1998;153(3):1001-4.
1998: E D Hsi; Kimberly E Foreman; J Duggan; Serhan Alkan; Carol A Kauffman; H D Aronow; Brian J Nickoloff
Molecular and pathologic characterization of an AIDS-related body cavity-based lymphoma, including ultrastructural demonstration of human herpesvirus-8: a case report.
The American journal of surgical pathology 1998;22(4):493-9.
1998: C Gutierrez-Steil; T Wrone-Smith; X Sun; J G Krueger; TR Coven; Brian J Nickoloff
Sunlight-induced basal cell carcinoma tumor cells and ultraviolet-B-irradiated psoriatic plaques express Fas ligand (CD95L).
The Journal of clinical investigation 1998;101(1):33-9.
1997: B K Bonish; Kimberly E Foreman; C Gutierrez-Steil; Brian J Nickoloff
Phenotype and proliferation characteristics of cultured spindle-shaped cells obtained from normal human skin and lesions of dermatofibroma, Kaposi's sarcoma, and dermatofibrosarcoma protuberans: a comparison with fibroblast and endothelial cells of the dermis.
Journal of dermatological science 1997;16(1):52-8.
1997: T Wrone-Smith; Raj S Mitra; Craig Thompson; Rama Jasty; Valerie P Castle; Brian J Nickoloff
Keratinocytes derived from psoriatic plaques are resistant to apoptosis compared with normal skin.
The American journal of pathology 1997;151(5):1321-9.
1997: Kimberly E Foreman; Patricia Bacon; E D Hsi; Brian J Nickoloff
In situ polymerase chain reaction-based localization studies support role of human herpesvirus-8 as the cause of two AIDS-related neoplasms: Kaposi's sarcoma and body cavity lymphoma.
The Journal of clinical investigation 1997;99(12):2971-8.
1997: Nora G Singer; R Mitra; F Lialios; Bruce C Richardson; Rory M Marks; J M Pesando; David A Fox; Brian J Nickoloff
CD6 dependent interactions of T cells and keratinocytes: functional evidence for a second CD6 ligand on gamma-interferon activated keratinocytes.
Immunology letters 1997;58(1):9-14.
1997: Kimberly E Foreman; Jacques Friborg; Wing-Pui Kong; C Woffendin; Peter J Polverini; Brian J Nickoloff; Gary Nabel
Propagation of a human herpesvirus from AIDS-associated Kaposi's sarcoma.
The New England journal of medicine 1997;336(3):163-71.
1997: Raj S Mitra; T Wrone-Smith; PL Simonian; Kimberly E Foreman; Gabriel Nunez; Brian J Nickoloff
Apoptosis in keratinocytes is not dependent on induction of differentiation.
Laboratory investigation; a journal of technical methods and pathology 1997;76(1):99-107.
1997: Kimberly E Foreman; Brian Bonish; Brian J Nickoloff
Absence of human herpesvirus 8 DNA sequences in patients with immunosuppression-associated dermatofibromas.
Archives of dermatology 1997;133(1):108-9.
1996: Gary Nabel; David F Gordon; D Keith Bishop; Brian J Nickoloff; ZY Yang; Atsushi Aruga; Mark Cameron; Elizabeth G Nabel; Alfred E Chang
Immune response in human melanoma after transfer of an allogeneic class I major histocompatibility complex gene with DNA-liposome complexes.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(26):15388-93.
1996: T Wrone-Smith; Brian J Nickoloff
Dermal injection of immunocytes induces psoriasis.
The Journal of clinical investigation 1996;98(8):1878-87.
1996: Kimberly E Foreman; T Wrone-Smith; Lawrence Boise; Craig Thompson; Peter J Polverini; PL Simonian; Gabriel Nunez; Brian J Nickoloff
Kaposi's sarcoma tumor cells preferentially express Bcl-xL.
The American journal of pathology 1996;149(3):795-803.
1996: Kimberly E Foreman; D Trinh; F O Nestle; Raj S Mitra; Brian J Nickoloff
Cultured Kaposi's sarcoma tumor cells fail to stimulate T cell proliferation.
Clinical immunology and immunopathology 1996;78(2):172-9.
1996: E D Hsi; Brian J Nickoloff
Dermatofibroma and dermatofibrosarcoma protuberans: an immunohistochemical study reveals distinctive antigenic profiles.
Journal of dermatological science 1996;11(1):1-9.
1996: C Tsai; Luis Alberto Diaz; N G Singer; L L Li; Anita H Kirsch; R Mitra; Brian J Nickoloff; Leslie J Crofford; David A Fox
Responsiveness of human T lymphocytes to bacterial superantigens presented by cultured rheumatoid arthritis synoviocytes.
Arthritis and rheumatism 1996;39(1):125-36.
1995: Laurence A Turka; RE Goodman; JL Rutkowski; Anders A F Sima; A Merry; Raj S Mitra; T Wrone-Smith; Galen Toews; Robert M Strieter; Brian J Nickoloff
Interleukin 12: a potential link between nerve cells and the immune response in inflammatory disorders.
Molecular medicine (Cambridge, Mass.) 1995;1(6):690-9.
1995: Brian J Nickoloff; Laurence A Turka; Raj S Mitra; F O Nestle
Direct and indirect control of T-cell activation by keratinocytes.
The Journal of investigative dermatology 1995;105(1 Suppl):25S-29S.
1995: T Wrone-Smith; Timothy R B Johnson; B Nelson; Lawrence Boise; Craig Thompson; Gabriel Núñez; Brian J Nickoloff
Discordant expression of Bcl-x and Bcl-2 by keratinocytes in vitro and psoriatic keratinocytes in vivo.
The American journal of pathology 1995;146(5):1079-88.
1995: Raj S Mitra; T A Judge; F O Nestle; Laurence A Turka; Brian J Nickoloff
Psoriatic skin-derived dendritic cell function is inhibited by exogenous IL-10. Differential modulation of B7-1 (CD80) and B7-2 (CD86) expression.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(6):2668-77.
1995: Brian J Nickoloff; Steven Kunkel; Marie Burdick; Robert M Strieter
Severe combined immunodeficiency mouse and human psoriatic skin chimeras. Validation of a new animal model.
The American journal of pathology 1995;146(3):580-8.
1995: Peter J Polverini; Brian J Nickoloff
The role of scatter factor and the c-met proto-oncogene in angiogenic responses.
EXS 1995;74():51-67.
1995: Peter J Polverini; Brian J Nickoloff
Role of scatter factor and the c-met protooncogene in the pathogenesis of AIDS-associated Kaposi's sarcoma.
Advances in cancer research 1995;66():235-53.
1994: Brian J Nickoloff; Laurence A Turka
Immunological functions of non-professional antigen-presenting cells: new insights from studies of T-cell interactions with keratinocytes.
Immunology today 1994;15(10):464-9.
1994: F O Nestle; Raj S Mitra; C F Bennett; H Chan; Brian J Nickoloff
Cationic lipid is not required for uptake and selective inhibitory activity of ICAM-1 phosphorothioate antisense oligonucleotides in keratinocytes.
The Journal of investigative dermatology 1994;103(4):569-75.
1994: Brian J Nickoloff; David P Fivenson; Steven Kunkel; Robert M Strieter; L A Turka
Keratinocyte interleukin-10 expression is upregulated in tape-stripped skin, poison ivy dermatitis, and Sezary syndrome, but not in psoriatic plaques.
Clinical immunology and immunopathology 1994;73(1):63-8.
1994: F O Nestle; Laurence A Turka; Brian J Nickoloff
Characterization of dermal dendritic cells in psoriasis. Autostimulation of T lymphocytes and induction of Th1 type cytokines.
The Journal of clinical investigation 1994;94(1):202-9.
1994: Y M Naidu; E M Rosen; R Zitnick; I Goldberg; M Park; M Naujokas; Peter J Polverini; Brian J Nickoloff
Role of scatter factor in the pathogenesis of AIDS-related Kaposi sarcoma.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(12):5281-5.
1994: RE Goodman; F Nestle; Y M Naidu; J M Green; Craig Thompson; Brian J Nickoloff; Laurence A Turka
Keratinocyte-derived T cell costimulation induces preferential production of IL-2 and IL-4 but not IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(11):5189-98.
1994: F O Nestle; Craig Thompson; Yoji Shimizu; Laurence A Turka; Brian J Nickoloff
Costimulation of superantigen-activated T lymphocytes by autologous dendritic cells is dependent on B7.
Cellular immunology 1994;156(1):220-9.
1994: Brian J Nickoloff; F O Nestle; X G Zheng; Laurence A Turka
T lymphocytes in skin lesions of psoriasis and mycosis fungoides express B7-1: a ligand for CD28.
Blood 1994;83(9):2580-6.
1994: F O Nestle; Brian J Nickoloff
Role of dendritic cells in benign and malignant lymphocytic infiltrates of the skin.
Dermatologic clinics 1994;12(2):271-82.
1994: Brian J Nickoloff; Raj S Mitra; James Varani; Xiaodong Huang; Peter J Polverini
Aberrant production of interleukin-8 and thrombospondin-1 by psoriatic keratinocytes mediates angiogenesis.
The American journal of pathology 1994;144(4):820-8.
1994: Brian J Nickoloff; Y Naidu
Perturbation of epidermal barrier function correlates with initiation of cytokine cascade in human skin.
Journal of the American Academy of Dermatology 1994;30(4):535-46.
1993: F O Nestle; X G Zheng; Craig Thompson; Laurence A Turka; Brian J Nickoloff
Characterization of dermal dendritic cells obtained from normal human skin reveals phenotypic and functionally distinctive subsets.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(11):6535-45.
1993: Brian J Nickoloff; Raj S Mitra; J Green; Yoji Shimizu; Craig Thompson; Laurence A Turka
Activated keratinocytes present bacterial-derived superantigens to T lymphocytes: relevance to psoriasis.
Journal of dermatological science 1993;6(2):127-33.
1993: Sharon W Weiss; Brian J Nickoloff
CD-34 is expressed by a distinctive cell population in peripheral nerve, nerve sheath tumors, and related lesions.
The American journal of surgical pathology 1993;17(10):1039-45.
1993: Raj S Mitra; Y Shimizu; Brian J Nickoloff
Histamine and cis-urocanic acid augment tumor necrosis factor-alpha mediated induction of keratinocyte intercellular adhesion molecule-1 expression.
Journal of cellular physiology 1993;156(2):348-57.
1993: Lawrence R Zukerberg; Brian J Nickoloff; Sharon W Weiss
Kaposiform hemangioendothelioma of infancy and childhood. An aggressive neoplasm associated with Kasabach-Merritt syndrome and lymphangiomatosis.
The American journal of surgical pathology 1993;17(4):321-8.
1993: Brian J Nickoloff; Raj S Mitra; K Lee; Laurence A Turka; J Green; Craig Thompson; Yoji Shimizu
Discordant expression of CD28 ligands, BB-1, and B7 on keratinocytes in vitro and psoriatic cells in vivo.
The American journal of pathology 1993;142(4):1029-40.
1993: Brian J Nickoloff; Raj S Mitra; J Green; X G Zheng; Yoji Shimizu; Craig Thompson; Laurence A Turka
Accessory cell function of keratinocytes for superantigens. Dependence on lymphocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(6):2148-59.
1992: K A Carr; S M Bulengo-Ransby; L M Weiss; Brian J Nickoloff; S Bulengo
Lymphoepitheliomalike carcinoma of the skin. A case report with immunophenotypic analysis and in situ hybridization for Epstein-Barr viral genome.
The American journal of surgical pathology 1992;16(9):909-13.
1992: Brian J Nickoloff; Raj S Mitra; Yoji Shimizu; J N Barker; G Karabin; T Stoof; Lloyd M Stoolman
HUT 78 T cells bind to noncytokine-stimulated keratinocytes using a non-CD18-dependent adhesion pathway.
The American journal of pathology 1992;140(6):1365-74.
1992: Raj S Mitra; Brian J Nickoloff
Epidermal growth factor and transforming growth factor-alpha decrease gamma interferon receptors and induction of intercellular adhesion molecule (ICAM-1) on cultured keratinocytes.
Journal of cellular physiology 1992;150(2):264-8.
1992: T J Stoof; Raj S Mitra; J Vidya Sarma; Xiaodong Huang; Brian J Nickoloff
Keratinocyte activation following T-lymphocyte binding.
The Journal of investigative dermatology 1992;98(1):92-5.
1992: Brian J Nickoloff
Pathophysiology of cutaneous inflammation.
Archives of dermatological research 1992;284 Suppl 1():S10-1.
1991: J N Barker; M L Jones; Raj S Mitra; E Crockett-Torabe; Joseph C Fantone III; Steven Kunkel; Jeffrey S Warren; Xiaodong Huang; Brian J Nickoloff
Modulation of keratinocyte-derived interleukin-8 which is chemotactic for neutrophils and T lymphocytes.
The American journal of pathology 1991;139(4):869-76.
1991: Christopher E M Griffiths; J N Barker; Steven Kunkel; Brian J Nickoloff
Modulation of leucocyte adhesion molecules, a T-cell chemotaxin (IL-8) and a regulatory cytokine (TNF-alpha) in allergic contact dermatitis (rhus dermatitis).
The British journal of dermatology 1991;124(6):519-26.
1991: Brian J Nickoloff; Christopher E M Griffiths
Aberrant intercellular adhesion molecule-1 (ICAM-1) expression by hair-follicle epithelial cells and endothelial leukocyte adhesion molecule-1 (ELAM-1) by vascular cells are important adhesion-molecule alterations in alopecia areata.
The Journal of investigative dermatology 1991;96(5):91S-92S.
1991: Gary J Fisher; J Esmann; Christopher E M Griffiths; H S Talwar; Elizabeth A Duell; Craig Hammerberg; James T Elder; L J Finkel; G D Karabin; Brian J Nickoloff
Cellular, immunologic and biochemical characterization of topical retinoic acid-treated human skin.
The Journal of investigative dermatology 1991;96(5):699-707.
1991: Brian J Nickoloff
The human progenitor cell antigen (CD34) is localized on endothelial cells, dermal dendritic cells, and perifollicular cells in formalin-fixed normal skin, and on proliferating endothelial cells and stromal spindle-shaped cells in Kaposi's sarcoma.
Archives of dermatology 1991;127(4):523-9.
1991: J N Barker; G D Karabin; T J Stoof; J Vidya Sarma; Xiaodong Huang; Brian J Nickoloff
Detection of interferon-gamma mRNA in psoriatic epidermis by polymerase chain reaction.
Journal of dermatological science 1991;2(2):106-11.
1991: J N Barker; M L Jones; C L Swenson; J Vidya Sarma; Raj S Mitra; Peter A Ward; Kent J Johnson; Joseph C Fantone III; Xiaodong Huang; Brian J Nickoloff
Monocyte chemotaxis and activating factor production by keratinocytes in response to IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(4):1192-7.
1991: J N Barker; Raj S Mitra; Christopher E M Griffiths; Xiaodong Huang; Brian J Nickoloff
Keratinocytes as initiators of inflammation.
Lancet 1991;337(8735):211-4.
1991: S M Bulengo-Ransby; M D Brown; H V Dubin; J E Rasmussen; Brian J Nickoloff
Sweet's syndrome presenting as an unusual periorbital eruption.
Journal of the American Academy of Dermatology 1991;24(1):140-1.
1991: Brian J Nickoloff; G D Karabin; J N Barker; Christopher E M Griffiths; J Vidya Sarma; Raj S Mitra; James T Elder; Steven Kunkel; Xiaodong Huang
Cellular localization of interleukin-8 and its inducer, tumor necrosis factor-alpha in psoriasis.
The American journal of pathology 1991;138(1):129-40.
1990: Brian J Nickoloff; E M Griffiths
Abnormal cutaneous topobiology: the molecular basis for dermatopathologic mononuclear cell patterns in inflammatory skin disease.
The Journal of investigative dermatology 1990;95(6 Suppl):128S-131S.
1990: Brian J Nickoloff; Christopher E M Griffiths
Lymphocyte trafficking in psoriasis: a new perspective emphasizing the dermal dendrocyte with active dermal recruitment mediated via endothelial cells followed by intra-epidermal T-cell activation.
The Journal of investigative dermatology 1990;95(5 Suppl):35S-37S.
1990: L T Elder; S B Klein; A Tavakkol; Gary J Fisher; Brian J Nickoloff; John J Voorhees
Growth factor and proto-oncogene expression in psoriasis.
The Journal of investigative dermatology 1990;95(5 Suppl):7S-9S.
1990: James T Elder; S B Klein; A Tavakkol; Gary J Fisher; Brian J Nickoloff; John J Voorhees
Growth factor and proto-oncogene expression in psoriasis.
The Journal of investigative dermatology 1990;95(5):7S-9S.
1990: Brian J Nickoloff; Christopher E M Griffiths
Lymphocyte trafficking in psoriasis: a new perspective emphasizing the dermal dendrocyte with active dermal recruitment mediated via endothelial cells followed by intra-epidermal T-cell activation.
The Journal of investigative dermatology 1990;95(5):35S-37S.
1990: Brian J Nickoloff; G S Wood; M Chu; J H Beckstead; Christopher E M Griffiths
Disseminated dermal dendrocytomas. A new cutaneous fibrohistiocytic proliferative disorder?
The American journal of surgical pathology 1990;14(9):867-71.
1990: James Varani; J Shayevitz; D Perry; Raj S Mitra; Brian J Nickoloff; John J Voorhees
Retinoic acid stimulation of human dermal fibroblast proliferation is dependent on suboptimal extracellular Ca2+ concentration.
The American journal of pathology 1990;136(6):1275-81.
1990: Brian J Nickoloff; Christopher E M Griffiths; J N Barker
The role of adhesion molecules, chemotactic factors, and cytokines in inflammatory and neoplastic skin disease--1990 update.
The Journal of investigative dermatology 1990;94(6 Suppl):151S-157S.
1990: James Varani; Raj S Mitra; D Gibbs; Sem H Phan; Xiaodong Huang; R Mitra; Timothy S Wang; K J Siebert; Brian J Nickoloff; John J Voorhees
All-trans retinoic acid stimulates growth and extracellular matrix production in growth-inhibited cultured human skin fibroblasts.
The Journal of investigative dermatology 1990;94(5):717-23.
1990: R S Taylor; Christopher E M Griffiths; M D Brown; Neil A Swanson; Brian J Nickoloff
Constitutive absence and interferon-gamma-induced expression of adhesion molecules in basal cell carcinoma.
Journal of the American Academy of Dermatology 1990;22(5 Pt 1):721-6.
1990: Aditya K Gupta; Charles Ellis; M T Siegel; Elizabeth A Duell; Christopher E M Griffiths; Ted A Hamilton; Brian J Nickoloff; John J Voorhees
Sulfasalazine improves psoriasis. A double-blind analysis.
Archives of dermatology 1990;126(4):487-93.
1990: Aditya K Gupta; Charles Ellis; Brian J Nickoloff; Michael T Goldfarb; V C Ho; L L Rocher; Christopher E M Griffiths; Kevin D Cooper; John J Voorhees
Oral cyclosporine in the treatment of inflammatory and noninflammatory dermatoses. A clinical and immunopathologic analysis.
Archives of dermatology 1990;126(3):339-50.
1990: Christopher E M Griffiths; J Esmann; Gary J Fisher; John J Voorhees; Brian J Nickoloff
Differential modulation of keratinocyte intercellular adhesion molecule-I expression by gamma interferon and phorbol ester: evidence for involvement of protein kinase C signal transduction.
The British journal of dermatology 1990;122(3):333-42.
1990: Aditya K Gupta; Charles Ellis; Kevin D Cooper; Brian J Nickoloff; V C Ho; Lawrence S Chan; Ted A Hamilton; D C Tellner; Christopher E M Griffiths; John J Voorhees
Oral cyclosporine for the treatment of alopecia areata. A clinical and immunohistochemical analysis.
Journal of the American Academy of Dermatology 1990;22(2 Pt 1):242-50.
1990: J N Barker; J Vidya Sarma; Raj S Mitra; Xiaodong Huang; Brian J Nickoloff
Marked synergism between tumor necrosis factor-alpha and interferon-gamma in regulation of keratinocyte-derived adhesion molecules and chemotactic factors.
The Journal of clinical investigation 1990;85(2):605-8.
1990: Brian J Nickoloff; Christopher E M Griffiths
Intraepidermal but not dermal T lymphocytes are positive for a cell-cycle-associated antigen (Ki-67) in mycosis fungoides.
The American journal of pathology 1990;136(2):261-6.
1990: V C Ho; Christopher E M Griffiths; Charles Ellis; Aditya K Gupta; C C McCuaig; Brian J Nickoloff; Kevin D Cooper; Ted A Hamilton; John J Voorhees
Intralesional cyclosporine in the treatment of psoriasis. A clinical, immunologic, and pharmacokinetic study.
Journal of the American Academy of Dermatology 1990;22(1):94-100.
1990: V C Ho; Aditya K Gupta; Charles Ellis; Brian J Nickoloff; John J Voorhees
Treatment of severe lichen planus with cyclosporine.
Journal of the American Academy of Dermatology 1990;22(1):64-8.
1990: Bruce L Riser; James Varani; Brian J Nickoloff; Raj S Mitra; Xiaodong Huang
Thrombospondin binding by keratinocytes: modulation under conditions which alter thrombospondin biosynthesis.
Dermatologica 1990;180(2):60-5.
1989: Christopher E M Griffiths; Brian J Nickoloff
Keratinocyte intercellular adhesion molecule-1 (ICAM-1) expression precedes dermal T lymphocytic infiltration in allergic contact dermatitis (Rhus dermatitis).
The American journal of pathology 1989;135(6):1045-53.
1989: Brian J Nickoloff; Raj S Mitra
Inhibition of 125I-epidermal growth factor binding to cultured keratinocytes by antiproliferative molecules gamma interferon, cyclosporin A, and transforming growth factor-beta.
The Journal of investigative dermatology 1989;93(6):799-803.
1989: Brian J Nickoloff; Christopher E M Griffiths
The spindle-shaped cells in cutaneous Kaposi's sarcoma. Histologic simulators include factor XIIIa dermal dendrocytes.
The American journal of pathology 1989;135(5):793-800.
1989: James Varani; Brian J Nickoloff; Xiaodong Huang; Raj S Mitra; John J Voorhees
All-trans retinoic acid stimulates growth of adult human keratinocytes cultured in growth factor-deficient medium, inhibits production of thrombospondin and fibronectin, and reduces adhesion.
The Journal of investigative dermatology 1989;93(4):449-54.
1989: Aditya K Gupta; Gary J Fisher; James T Elder; H S Talwar; J Esmann; Elizabeth A Duell; Brian J Nickoloff; John J Voorhees
Topical cyclosporine A inhibits the phorbol ester induced hyperplastic inflammatory response but not protein kinase C activation in mouse epidermis.
The Journal of investigative dermatology 1989;93(3):379-86.
1989: Brian J Nickoloff; Raj S Mitra; James T Elder; Gary J Fisher; John J Voorhees
Decreased growth inhibition by recombinant gamma interferon is associated with increased transforming growth factor-alpha production in keratinocytes cultured from psoriatic lesions.
The British journal of dermatology 1989;121(2):161-74.
1989: J T Headington; Aditya K Gupta; Michael T Goldfarb; Brian J Nickoloff; Ted A Hamilton; Charles Ellis; John J Voorhees
A morphometric and histologic study of the scalp in psoriasis. Paradoxical sebaceous gland atrophy and decreased hair shaft diameters without alopecia.
Archives of dermatology 1989;125(5):639-42.
1989: Brian J Nickoloff; Christopher E M Griffiths
T lymphocytes and monocytes bind to keratinocytes in frozen sections of biopsy specimens of normal skin treated with gamma interferon.
Journal of the American Academy of Dermatology 1989;20(5 Pt 1):736-43.
1989: Brian J Nickoloff; Christopher E M Griffiths; O Baadsgaard; John J Voorhees; C A Hanson; Kevin D Cooper
Markedly diminished epidermal keratinocyte expression of intercellular adhesion molecule-1 (ICAM-1) in Sézary syndrome.
JAMA : the journal of the American Medical Association 1989;261(15):2217-21.
1989: V C Ho; Aditya K Gupta; Charles Ellis; Kevin D Cooper; Brian J Nickoloff; John J Voorhees
Cyclosporine in lamellar ichthyosis.
Archives of dermatology 1989;125(4):511-4.
1989: Christopher E M Griffiths; John J Voorhees; Brian J Nickoloff
Characterization of intercellular adhesion molecule-1 and HLA-DR expression in normal and inflamed skin: modulation by recombinant gamma interferon and tumor necrosis factor.
Journal of the American Academy of Dermatology 1989;20(4):617-29.
1989: James Varani; Raj S Mitra; B J McClenic; S E Fligiel; D R Inman; Xiaodong Huang; Brian J Nickoloff
Modulation of fibronectin production in normal human melanocytes and malignant melanoma cells by interferon-gamma and tumor necrosis factor-alpha.
The American journal of pathology 1989;134(4):827-36.
1989: Brian J Nickoloff; Christopher E M Griffiths
Factor XIIIa-expressing dermal dendrocytes in AIDS-associated cutaneous Kaposi's sarcomas.
Science (New York, N.Y.) 1989;243(4899):1736-7.
1989: B K McClenic; Raj S Mitra; Bruce L Riser; Brian J Nickoloff; Xiaodong Huang; James Varani
Production and utilization of extracellular matrix components by human melanocytes.
Experimental cell research 1989;180(2):314-25.
1989: Christopher E M Griffiths; John J Voorhees; Brian J Nickoloff
Gamma interferon induces different keratinocyte cellular patterns of expression of HLA-DR and DQ and intercellular adhesion molecule-I (ICAM-I) antigens.
The British journal of dermatology 1989;120(1):1-8.
1988: Brian J Nickoloff
Role of interferon-gamma in cutaneous trafficking of lymphocytes with emphasis on molecular and cellular adhesion events.
Archives of dermatology 1988;124(12):1835-43.
1988: Brian J Nickoloff
Light-microscopic assessment of 100 patients with patch/plaque-stage mycosis fungoides.
The American Journal of dermatopathology 1988;10(6):469-77.
1988: Aditya K Gupta; Gary J Fisher; James T Elder; Brian J Nickoloff; John J Voorhees
Sphingosine inhibits phorbol ester-induced inflammation, ornithine decarboxylase activity, and activation of protein kinase C in mouse skin.
The Journal of investigative dermatology 1988;91(5):486-91.
1988: Brian J Nickoloff; Raj S Mitra; Bruce L Riser; Xiaodong Huang; James Varani
Modulation of keratinocyte motility. Correlation with production of extracellular matrix molecules in response to growth promoting and antiproliferative factors.
The American journal of pathology 1988;132(3):543-51.
1988: Brian J Nickoloff; Bruce L Riser; Raj S Mitra; Xiaodong Huang; James Varani
Inhibitory effect of gamma interferon on cultured human keratinocyte thrombospondin production, distribution, and biologic activities.
The Journal of investigative dermatology 1988;91(3):213-8.
1988: Gary J Fisher; Elizabeth A Duell; Brian J Nickoloff; Thomas M Annesley; J K Kowalke; Charles Ellis; John J Voorhees
Levels of cyclosporin in epidermis of treated psoriasis patients differentially inhibit growth of keratinocytes cultured in serum free versus serum containing media.
The Journal of investigative dermatology 1988;91(2):142-6.
1988: Brian J Nickoloff; Gary J Fisher; Raj S Mitra; John J Voorhees
Direct cytopathic effects of cyclosporine A on rapidly proliferating cultured keratinocytes and dermal fibroblasts.
Transplantation proceedings 1988;20(3 Suppl 4):85-90.
1988: James Varani; Brian J Nickoloff; Bruce L Riser; Raj S Mitra; K O'Rourke; Xiaodong Huang
Thrombospondin-induced adhesion of human keratinocytes.
The Journal of clinical investigation 1988;81(5):1537-44.
1988: Brian J Nickoloff; Raj S Mitra
Phorbol ester treatment enhances binding of mononuclear leukocytes to autologous and allogeneic gamma-interferon-treated keratinocytes, which are blocked by anti-LFA-1 monoclonal antibody.
The Journal of investigative dermatology 1988;90(5):684-9.
1988: Brian J Nickoloff; Gary J Fisher; Raj S Mitra; John J Voorhees
Additive and synergistic antiproliferative effects of cyclosporin A and gamma interferon on cultured human keratinocytes.
The American journal of pathology 1988;131(1):12-8.
1988: Brian J Nickoloff
Keratinocytes produce a lymphocyte inhibitory factor which is partially reversible by an antibody to transforming growth factor-beta.
Annals of the New York Academy of Sciences 1988;548():312-20.
1987: Brian J Nickoloff; David M Lewinsohn; E C Butcher
Enhanced binding of peripheral blood mononuclear leukocytes to gamma-interferon-treated cultured keratinocytes.
The American Journal of dermatopathology 1987;9(5):413-8.