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Allen Nickols

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Srinivasan R Nagarajan; Balekudru Devadas; James W Malecha; Hwang-Fun Lu; Peter G Ruminski; Joseph G Rico; Thomas E Rogers; Laura D Marrufo; Joe T Collins; H Peter Kleine; Melissa K Lantz; Jun Zhu; Nawasa F Green; Mark A Russell; Bryan H Landis; Lawrence M Miller; Debra M Meyer; Tiffany Duffin; V Wayne Engleman; Mary Beth Finn; Sandra K Freeman; David W Griggs; Melanie L Williams; Maureen A Nickols; Jodi A Pegg; Kristen E Shannon; Christina N Steininger; Marisa M Westlin; G Allen Nickols; Jeffery L Keene
R-isomers of Arg-Gly-Asp (RGD) mimics as potent alphavbeta3 inhibitors.
Srinivasan R Nagarajan; Hwang-Fun Lu; Alan F Gasiecki; Ish K Khanna; Mihir D Parikh; Bipin N Desai; Thomas E Rogers; Michael Clare; Barbara B Chen; Mark A Russell; Jeffery L Keene; Tiffany Duffin; V Wayne Engleman; Mary Beth Finn; Sandra K Freeman; Jon A Klover; G Allen Nickols; Maureen A Nickols; Kristen E Shannon; Christina A Steininger; William F Westlin; Marisa M Westlin; Melanie L Williams
Discovery of +(2-{4-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]phenyl}-cyclopropyl)acetic acid as potent and selective alphavbeta3 inhibitor: design, synthesis, and optimization.
Thomas D Penning; Albert Khilevich; Barbara B Chen; Mark A Russell; Mark L Boys; Yaping Wang; Tiffany Duffin; V Wayne Engleman; Mary Beth Finn; Sandra K Freeman; Melanie L Hanneke; Jeffery L Keene; Jon A Klover; G Allen Nickols; Maureen A Nickols; Randall K Rader; Steven L Settle; Kristen E Shannon; Christina N Steininger; Marisa M Westlin; William F Westlin
Synthesis of pyrazoles and isoxazoles as potent alpha(v)beta3 receptor antagonists.

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2007: Srinivasan R Nagarajan; Balekudru Devadas; James W Malecha; Hwang-Fun Lu; Peter G Ruminski; Joseph G Rico; Thomas E Rogers; Laura D Marrufo; Joe T Collins; H Peter Kleine; Melissa K Lantz; Jun Zhu; Nawasa F Green; Mark A Russell; Bryan H Landis; Lawrence M Miller; Debra M Meyer; Tiffany Duffin; V Wayne Engleman; Mary Beth Finn; Sandra K Freeman; David W Griggs; Melanie L Williams; Maureen A Nickols; Jodi A Pegg; Kristen E Shannon; Christina N Steininger; Marisa M Westlin; G Allen Nickols; Jeffery L Keene
R-isomers of Arg-Gly-Asp (RGD) mimics as potent alphavbeta3 inhibitors.
Bioorganic & medicinal chemistry 2007;15(11):3783-800.
2007: Srinivasan R Nagarajan; Hwang-Fun Lu; Alan F Gasiecki; Ish K Khanna; Mihir D Parikh; Bipin N Desai; Thomas E Rogers; Michael Clare; Barbara B Chen; Mark A Russell; Jeffery L Keene; Tiffany Duffin; V Wayne Engleman; Mary Beth Finn; Sandra K Freeman; Jon A Klover; G Allen Nickols; Maureen A Nickols; Kristen E Shannon; Christina A Steininger; William F Westlin; Marisa M Westlin; Melanie L Williams
Discovery of +(2-{4-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]phenyl}-cyclopropyl)acetic acid as potent and selective alphavbeta3 inhibitor: design, synthesis, and optimization.
Bioorganic & medicinal chemistry 2007;15(10):3390-412.
2006: Thomas D Penning; Albert Khilevich; Barbara B Chen; Mark A Russell; Mark L Boys; Yaping Wang; Tiffany Duffin; V Wayne Engleman; Mary Beth Finn; Sandra K Freeman; Melanie L Hanneke; Jeffery L Keene; Jon A Klover; G Allen Nickols; Maureen A Nickols; Randall K Rader; Steven L Settle; Kristen E Shannon; Christina N Steininger; Marisa M Westlin; William F Westlin
Synthesis of pyrazoles and isoxazoles as potent alpha(v)beta3 receptor antagonists.
Bioorganic & medicinal chemistry letters 2006;16(12):3156-61.
2006: John A Wendt; Hongwei Wu; Heather G Stenmark; Mark L Boys; Victoria L Downs; Thomas D Penning; Barbara B Chen; Yaping Wang; Tiffany Duffin; Mary Beth Finn; Jeffery L Keene; V Wayne Engleman; Sandra K Freeman; Melanie L Hanneke; Kristen E Shannon; Maureen A Nickols; Christina N Steininger; Marisa M Westlin; Jon A Klover; William F Westlin; G Allen Nickols; Mark A Russell
Synthesis of 2,5-thiazole butanoic acids as potent and selective alpha(v)beta3 integrin receptor antagonists with improved oral pharmacokinetic properties.
Bioorganic & medicinal chemistry letters 2006;16(4):845-9.
2006: Srinivasan R Nagarajan; Jane M Meyer; Julie M Miyashiro; V Wayne Engleman; Sandra K Freeman; David W Griggs; Jon A Klover; G Allen Nickols
Discovery of diphenylmethanepropionic and dihydrostilbeneacetic acids as antagonists of the integrin alphavbeta3.
Chemical biology & drug design 2006;67(2):177-81.
2004: Thomas D Penning; Mark A Russell; Barbara B Chen; Helen Y Chen; Bipin N Desai; Stephen H Docter; David J Edwards; Glen J Gesicki; Chi-Dean Liang; James W Malecha; Stella S Yu; V Wayne Engleman; Sandra K Freeman; Melanie L Hanneke; Kristen E Shannon; Marisa M Westlin; G Allen Nickols
Synthesis of cinnamic acids and related isosteres as potent and selective alpha v beta 3 receptor antagonists.
Bioorganic & medicinal chemistry letters 2004;14(6):1471-6.
2000: CP Carron; Debra M Meyer; V Wayne Engleman; Joseph G Rico; Peter G Ruminski; R L Ornberg; William F Westlin; G Allen Nickols
Peptidomimetic antagonists of alphavbeta3 inhibit bone resorption by inhibiting osteoclast bone resorptive activity, not osteoclast adhesion to bone.
The Journal of endocrinology 2000;165(3):587-98.
1999: C M Schmidt; Steven L Settle; Jeffery L Keene; William F Westlin; G Allen Nickols; David W Griggs
Characterization of spontaneous metastasis in an aggressive breast carcinoma model using flow cytometry.
Clinical & experimental metastasis 1999;17(6):537-44.
1998: CP Carron; Debra M Meyer; J A Pegg; V Wayne Engleman; Maureen A Nickols; Steven L Settle; William F Westlin; Peter G Ruminski; G Allen Nickols
A peptidomimetic antagonist of the integrin alpha(v)beta3 inhibits Leydig cell tumor growth and the development of hypercalcemia of malignancy.
Cancer research 1998;58(9):1930-5.
1997: V Wayne Engleman; G Allen Nickols; F P Ross; M A Horton; David W Griggs; Steven L Settle; Peter G Ruminski; S L Teitelbaum
A peptidomimetic antagonist of the alpha(v)beta3 integrin inhibits bone resorption in vitro and prevents osteoporosis in vivo.
The Journal of clinical investigation 1997;99(9):2284-92.
1996: B A Crippes; V Wayne Engleman; Steven L Settle; J Delarco; R L Ornberg; M H Helfrich; M A Horton; G Allen Nickols
Antibody to beta3 integrin inhibits osteoclast-mediated bone resorption in the thyroparathyroidectomized rat.
Endocrinology 1996;137(3):918-24.
1995: Patricia Collin-Osdoby; G Allen Nickols; Philip Osdoby
Bone cell function, regulation, and communication: a role for nitric oxide.
Journal of cellular biochemistry 1995;57(3):399-408.
1995: T P Kasten; Steven L Settle; TP Misko; Dennis P Riley; R H Weiss; M G Currie; G Allen Nickols
Potentiation of nitric oxide-mediated vascular relaxation by SC52608, a superoxide dismutase mimic.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1995;208(2):170-7.
1994: T P Kasten; Patricia Collin-Osdoby; N Patel; Philip Osdoby; M Krukowski; TP Misko; Steven L Settle; M G Currie; G Allen Nickols
Potentiation of osteoclast bone-resorption activity by inhibition of nitric oxide synthase.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(9):3569-73.
1994: T P Kasten; Steven L Settle; TP Misko; M G Currie; G Allen Nickols
Manganese potentiation of nitric oxide-mediated vascular relaxation.
European journal of pharmacology 1994;253(1-2):35-43.
1993: TP Misko; William M Moore; T P Kasten; G Allen Nickols; J A Corbett; Ronald G Tilton; Michael L McDaniel; J R Williamson; M G Currie
Selective inhibition of the inducible nitric oxide synthase by aminoguanidine.
European journal of pharmacology 1993;233(1):119-25.
1992: Ryuichi Yamamoto; K Takasaki; G Allen Nickols
Purinergic vasoconstrictor component revealed by moderate cooling in the isolated mesenteric vasculature of Sprague-Dawley rats.
The Journal of pharmacology and experimental therapeutics 1992;262(3):1133-8.
1992: M Murakami; J Ishizuka; S Sumi; G Allen Nickols; CW Cooper; Courtney M Townsend; James C Thompson
Role of extracellular magnesium in insulin secretion from rat insulinoma cells.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1992;200(4):490-4.
1992: Donald J DiPette; W Christenson; M A Nickols; G Allen Nickols
Cardiovascular responsiveness to parathyroid hormone (PTH) and PTH-related protein in genetic hypertension.
Endocrinology 1992;130(4):2045-51.
1992: H Komidori; Ryuichi Yamamoto; G Allen Nickols; K Takasaki
Characterization of the isolated rat mesenteric vascular-intestinal loop preparation.
Journal of pharmacological and toxicological methods 1992;27(1):59-65.
1992: R R Townsend; Ryuichi Yamamoto; M Nickols; Donald J DiPette; G Allen Nickols
Insulin enhances pressor responses to norepinephrine in rat mesenteric vasculature.
Hypertension 1992;19(2 Suppl):II105-10.
1992: Ryuichi Yamamoto; G Allen Nickols; M A Nickols; D J DiPette; R R Townsend; K Takasaki
Reassessment of noradrenergic function in salt-induced hypertension in Dahl rats.
Japanese journal of pharmacology 1992;58 Suppl 2():274P.
1991: Jean-Jacques Helwig; M J Musso; C Judes; G Allen Nickols
Parathyroid hormone and calcium: interactions in the control of renin secretion in the isolated, nonfiltering rat kidney.
Endocrinology 1991;129(3):1233-42.
1991: A Roca-Cusachs; Donald J DiPette; G Allen Nickols
Regional and systemic hemodynamic effects of parathyroid hormone-related protein: preservation of cardiac function and coronary and renal flow with reduced blood pressure.
The Journal of pharmacology and experimental therapeutics 1991;256(1):110-8.
1990: P Volpe; B H Alderson-Lang; G Allen Nickols
Regulation of inositol 1,4,5-trisphosphate-induced Ca2+ release. I. Effect of Mg2+.
The American journal of physiology 1990;258(6 Pt 1):C1077-85.
1990: Donald J DiPette; P E Greilich; G Allen Nickols; G A Graham; A Green; CW Cooper; O B Holland
Effect of dietary calcium supplementation on blood pressure and calciotropic hormones in mineralocorticoid-salt hypertension.
Journal of hypertension 1990;8(6):515-20.
1990: Patricia K Seitz; G Allen Nickols; M A Nickols; M B McPherson; CW Cooper
Radioiodinated rat parathyroid hormone-(1-34) binds to its receptor on rat osteosarcoma cells in a manner consistent with two classes of binding sites.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1990;5(4):353-9.
1990: G Allen Nickols; M A Nickols; Jean-Jacques Helwig
Binding of parathyroid hormone and parathyroid hormone-related protein to vascular smooth muscle of rabbit renal microvessels.
Endocrinology 1990;126(2):721-7.
1989: L L Mok; G Allen Nickols; James C Thompson; CW Cooper
Parathyroid hormone as a smooth muscle relaxant.
Endocrine reviews 1989;10(4):420-36.
1989: G Allen Nickols; A D Nana; M A Nickols; Donald J DiPette; Gregory K Asimakis
Hypotension and cardiac stimulation due to the parathyroid hormone-related protein, humoral hypercalcemia of malignancy factor.
Endocrinology 1989;125(2):834-41.
1989: G Allen Nickols; M A Metz-Nickols; P K Pang; M S Roberts; CW Cooper
Identification and characterization of parathyroid hormone receptors in rat renal cortical plasma membranes using radioligand binding.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1989;4(4):615-23.
1988: m twery; Patricia K Seitz; G Allen Nickols; CW Cooper; Joel P Gallagher; R C Orlowski
Analogue separates biological effects of salmon calcitonin on brain and renal cortical membranes.
European journal of pharmacology 1988;155(3):285-92.
1986: G A Dunaway; T P Kasten; G Allen Nickols; J A Chesky
Regulation of skeletal muscle 6-phosphofructo-1-kinase during aging and development.
Mechanisms of ageing and development 1986;36(1):13-23.