FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Christophe Nicot

Research Profile

Living Beings

Chemicals & Drugs

Disorders

Anatomy

Physiology

Co-author Network

Publications

TOP 3
Nga Ling Ko; Xue Tao Bai; Marcia Bellon; Miroslav Dundr; Sergey P Shevtsov; John M Taylor; Christophe Nicot
PA28γ is a novel corepressor of HTLV-1 replication and controls viral latency.
Yuan Yao; Shary N Shelton; Marcia Bellon; Christophe Nicot
Tumor suppressors p53, p63TAα, p63TAy, p73α, and p73β use distinct pathways to repress telomerase expression.
X T Bai; Marcia Bellon; N L Ko; Uma Sinha-Datta; Christophe Nicot
Nuclear export and expression of human T-cell leukemia virus type 1 tax/rex mRNA are RxRE/Rex dependent.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Christophe Nicot (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Nga Ling Ko; Xue Tao Bai; Marcia Bellon; Miroslav Dundr; Sergey P Shevtsov; John M Taylor; Christophe Nicot
PA28γ is a novel corepressor of HTLV-1 replication and controls viral latency.
Blood 2013;121(5):791-800.
2012: Yuan Yao; Shary N Shelton; Marcia Bellon; Christophe Nicot
Tumor suppressors p53, p63TAα, p63TAy, p73α, and p73β use distinct pathways to repress telomerase expression.
The Journal of biological chemistry 2012;287(24):20737-47.
2012: X T Bai; Marcia Bellon; N L Ko; Uma Sinha-Datta; Christophe Nicot
Nuclear export and expression of human T-cell leukemia virus type 1 tax/rex mRNA are RxRE/Rex dependent.
Journal of virology 2012;86(8):4559-65.
2012: Xue Tao Bai; Christophe Nicot
Overview on HTLV-1 p12, p8, p30, p13: accomplices in persistent infection and viral pathogenesis.
Frontiers in microbiology 2012;3():400.
2012: Hicham Hachem Baydoun; Xue Tao Bai; Shary Shelton; Christophe Nicot
HTLV-I tax increases genetic instability by inducing DNA double strand breaks during DNA replication and switching repair to NHEJ.
PloS one 2012;7(8):e42226.
2011: Vibeke Andresen; Marcia Bellon; Valentina Cecchinato; Risaku Fukumoto; Christophe Nicot; Cynthia A Pise-Masison; Uma Sinha-Datta; Valerio Valeri; R Washington Parks; Genoveffa Franchini
Suppression of HTLV-1 replication by Tax-mediated rerouting of the p13 viral protein to nuclear speckles.
Blood 2011;118(6):1549-59.
2011: Hicham Hachem Baydoun; Joanna Pancewicz; Christophe Nicot
Human T-lymphotropic type 1 virus p30 inhibits homologous recombination and favors unfaithful DNA repair.
Blood 2011;117(22):5897-906.
2011: Joanna Pancewicz; Christophe Nicot
Current views on the role of Notch signaling and the pathogenesis of human leukemia.
BMC cancer 2011;11():502.
2010: Valerio W Valeri; Anna Hryniewicz; Vibeke Andresen; Kathy Jones; Claudio Fenizia; Izabela Bialuk; Hye Kyung Chung; Risaku Fukumoto; Robyn Washington Parks; Maria Grazia Ferrari; Christophe Nicot; Valentina Cecchinato; Francis W Ruscetti; Genoveffa Franchini
Requirement of the human T-cell leukemia virus p12 and p30 products for infectivity of human dendritic cells and macaques but not rabbits.
Blood 2010;116(19):3809-17.
2010: Xue Tao Bai; Hicham Hachem Baydoun; Christophe Nicot
HTLV-I p30: a versatile protein modulating virus replication and pathogenesis.
Molecular aspects of medicine 2010;31(5):344-9.
2010: Joanna Pancewicz; John M Taylor; Abhik Datta; Hicham Hachem Baydoun; Thomas A Waldmann; Olivier Hermine; Christophe Nicot
Notch signaling contributes to proliferation and tumor formation of human T-cell leukemia virus type 1-associated adult T-cell leukemia.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(38):16619-24.
2010: Marcia Bellon; Hicham Hachem Baydoun; Yuan Yao; Christophe Nicot
HTLV-I Tax-dependent and -independent events associated with immortalization of human primary T lymphocytes.
Blood 2010;115(12):2441-8.
2010: Hicham Hachem Baydoun; Joanna Pancewicz; Xuetao Bai; Christophe Nicot
HTLV-I p30 inhibits multiple S phase entry checkpoints, decreases cyclin E-CDK2 interactions and delays cell cycle progression.
Molecular cancer 2010;9():302.
2009: J M Taylor; Megan Brown; Mohamed Nejmeddine; K J Kim; L Ratner; M Lairmore; Christophe Nicot
Novel role for interleukin-2 receptor-Jak signaling in retrovirus transmission.
Journal of virology 2009;83(22):11467-76.
2009: Marcia Bellon; yves lepelletier; Olivier Hermine; Christophe Nicot
Deregulation of microRNA involved in hematopoiesis and the immune response in HTLV-I adult T-cell leukemia.
Blood 2009;113(20):4914-7.
2009: Risaku Fukumoto; Vibeke Andresen; Izabela Bialuk; Valentina Cecchinato; Jean-Claude Walser; Valerio W Valeri; Julie M Nauroth; Antoine Gessain; Christophe Nicot; Genoveffa Franchini
In vivo genetic mutations define predominant functions of the human T-cell leukemia/lymphoma virus p12I protein.
Blood 2009;113(16):3726-34.
2009: John M Taylor; Sofiane Ghorbel; Christophe Nicot
Genome wide analysis of human genes transcriptionally and post-transcriptionally regulated by the HTLV-I protein p30.
BMC genomics 2009;10():311.
2008: Marcia Bellon; Christophe Nicot
Central role of PI3K in transcriptional activation of hTERT in HTLV-I-infected cells.
Blood 2008;112(7):2946-55.
2008: John M Taylor; Christophe Nicot
HTLV-1 and apoptosis: role in cellular transformation and recent advances in therapeutic approaches.
Apoptosis : an international journal on programmed cell death 2008;13(6):733-47.
2008: A Datta; Christophe Nicot
Telomere attrition induces a DNA double-strand break damage signal that reactivates p53 transcription in HTLV-I leukemic cells.
Oncogene 2008;27(8):1135-41.
2008: Marcia Bellon; Christophe Nicot
Regulation of telomerase and telomeres: human tumor viruses take control.
Journal of the National Cancer Institute 2008;100(2):98-108.
2008: Uma Sinha-Datta; John M Taylor; Megan Brown; Christophe Nicot
Celecoxib disrupts the canonical apoptotic network in HTLV-I cells through activation of Bax and inhibition of PKB/Akt.
Apoptosis : an international journal on programmed cell death 2008;13(1):33-40.
2007: Risaku Fukumoto; Miroslav Dundr; Christophe Nicot; Anthony Adams; Valerio W Valeri; Lawrence E Samelson; Genoveffa Franchini
Inhibition of T-cell receptor signal transduction and viral expression by the linker for activation of T cells-interacting p12(I) protein of human T-cell leukemia/lymphoma virus type 1.
Journal of virology 2007;81(17):9088-99.
2007: Vincent Lacoste; Christophe Nicot; Antoine Gessain; Françoise Valensi; Jean Gabarre; Hittu Matta; Preet M Chaudhary; Renaud Mahieux
In primary effusion lymphoma cells, MYB transcriptional repression is associated with v-FLIP expression during latent KSHV infection while both v-FLIP and v-GPCR become involved during the lytic cycle.
British journal of haematology 2007;138(4):487-501.
2007: Uma Sinha-Datta; Abhik Datta; Sofiane Ghorbel; Madeleine Duc Dodon; Christophe Nicot
Human T-cell lymphotrophic virus type I rex and p30 interactions govern the switch between virus latency and replication.
The Journal of biological chemistry 2007;282(19):14608-15.
2007: Megan Brown; Marcia Bellon; Christophe Nicot
Emodin and DHA potently increase arsenic trioxide interferon-alpha-induced cell death of HTLV-I-transformed cells by generation of reactive oxygen species and inhibition of Akt and AP-1.
Blood 2007;109(4):1653-9.
2007: Marcia Bellon; Christophe Nicot
Telomerase: a crucial player in HTLV-I-induced human T-cell leukemia.
Cancer genomics & proteomics 2007;4(1):21-5.
2006: Sofiane Ghorbel; Uma Sinha-Datta; Miroslav Dundr; Megan Brown; Genoveffa Franchini; Christophe Nicot
Human T-cell leukemia virus type I p30 nuclear/nucleolar retention is mediated through interactions with RNA and a constituent of the 60 S ribosomal subunit.
The Journal of biological chemistry 2006;281(48):37150-8.
2006: Marcia Bellon; Abhik Datta; Megan Brown; Jean-François Pouliquen; Pierre Couppie; Mirdad Kazanji; Christophe Nicot
Increased expression of telomere length regulating factors TRF1, TRF2 and TIN2 in patients with adult T-cell leukemia.
International journal of cancer. Journal international du cancer 2006;119(9):2090-7.
2006: Abhik Datta; Uma Sinha-Datta; Navneet Kaur Dhillon; Shilpa Buch; Christophe Nicot
The HTLV-I p30 interferes with TLR4 signaling and modulates the release of pro- and anti-inflammatory cytokines from human macrophages.
The Journal of biological chemistry 2006;281(33):23414-24.
2006: Abhik Datta; Marcia Bellon; Uma Sinha-Datta; Ali Bazarbachi; yves lepelletier; Danielle Canioni; Thomas Waldmann; Olivier Hermine; Christophe Nicot
Persistent inhibition of telomerase reprograms adult T-cell leukemia to p53-dependent senescence.
Blood 2006;108(3):1021-9.
2005: Christophe Nicot; Robert Harrod; Vincenzo Ciminale; Genoveffa Franchini
Human T-cell leukemia/lymphoma virus type 1 nonstructural genes and their functions.
Oncogene 2005;24(39):6026-34.
2005: Christophe Nicot
Current views in HTLV-I-associated adult T-cell leukemia/lymphoma.
American journal of hematology 2005;78(3):232-9.
2004: Uma Sinha-Datta; Izumi Horikawa; Eriko Michishita; Abhik Datta; Janitzia C Sigler-Nicot; Megan Brown; Mirdad Kazanji; J Carl Barrett; Christophe Nicot
Transcriptional activation of hTERT through the NF-kappaB pathway in HTLV-I-transformed cells.
Blood 2004;104(8):2523-31.
2004: Christophe Nicot; Miroslav Dundr; Julie M Johnson; Jake R Fullen; Norma Alonzo; Risaku Fukumoto; Gerald Princler; David Derse; Tom Misteli; Genoveffa Franchini
HTLV-1-encoded p30II is a post-transcriptional negative regulator of viral replication.
Nature medicine 2004;10(2):197-201.
2003: Genoveffa Franchini; Christophe Nicot; Julie M Johnson
Seizing of T cells by human T-cell leukemia/lymphoma virus type 1.
Advances in cancer research 2003;89():69-132.
2002: Bertrand Arnulf; Aude Villemain; Christophe Nicot; Elodie Mordelet; Pierre Charneau; Joelle Kersual; Yael Zermati; Alain Mauviel; Ali Bazarbachi; Olivier Hermine
Human T-cell lymphotropic virus oncoprotein Tax represses TGF-beta 1 signaling in human T cells via c-Jun activation: a potential mechanism of HTLV-I leukemogenesis.
Blood 2002;100(12):4129-38.
2001: Renaud Mahieux; Cynthia A Pise-Masison; Antoine Gessain; John N Brady; R Olivier; Emmanuelle Perret; T Misteli; Christophe Nicot
Arsenic trioxide induces apoptosis in human T-cell leukemia virus type 1- and type 2-infected cells by a caspase-3-dependent mechanism involving Bcl-2 cleavage.
Blood 2001;98(13):3762-9.
2001: Christophe Nicot; Renaud Mahieux; Cynthia A Pise-Masison; John Brady; Antoine Gessain; S Yamaoka; Genoveffa Franchini
Human T-cell lymphotropic virus type 1 Tax represses c-Myb-dependent transcription through activation of the NF-kappaB pathway and modulation of coactivator usage.
Molecular and cellular biology 2001;21(21):7391-402.
2001: Christophe Nicot; JC Mulloy; Maria Grazia Ferrari; Julie M Johnson; K Fu; Risaku Fukumoto; R Trovato; Jake R Fullen; Warren J Leonard; Genoveffa Franchini
HTLV-1 p12(I) protein enhances STAT5 activation and decreases the interleukin-2 requirement for proliferation of primary human peripheral blood mononuclear cells.
Blood 2001;98(3):823-9.
2001: Julie M Johnson; Christophe Nicot; Jake R Fullen; Vincenzo Ciminale; L Casareto; JC Mulloy; S Jacobson; Genoveffa Franchini
Free major histocompatibility complex class I heavy chain is preferentially targeted for degradation by human T-cell leukemia/lymphotropic virus type 1 p12(I) protein.
Journal of virology 2001;75(13):6086-94.
2000: Julie M Johnson; JC Mulloy; Vincenzo Ciminale; Jake R Fullen; Christophe Nicot; Genoveffa Franchini
The MHC class I heavy chain is a common target of the small proteins encoded by the 3' end of HTLV type 1 and HTLV type 2.
AIDS research and human retroviruses 2000;16(16):1777-81.
2000: Renaud Mahieux; Cynthia A Pise-Masison; Christophe Nicot; P Green; W W Hall; John N Brady
Inactivation of p53 by HTLV type 1 and HTLV type 2 Tax trans-activators.
AIDS research and human retroviruses 2000;16(16):1677-81.
2000: Christophe Nicot; Rene Opavsky; Renaud Mahieux; J M Johnson; John N Brady; Linda Wolff; Genoveffa Franchini
Tax oncoprotein trans-represses endogenous B-myb promoter activity in human T cells.
AIDS research and human retroviruses 2000;16(16):1629-32.
2000: Christophe Nicot; Robert Harrod
Distinct p300-responsive mechanisms promote caspase-dependent apoptosis by human T-cell lymphotropic virus type 1 Tax protein.
Molecular and cellular biology 2000;20(22):8580-9.
2000: Renaud Mahieux; Cynthia A Pise-Masison; Paul F Lambert; Christophe Nicot; L De Marchis; Antoine Gessain; P Green; W Hall; John N Brady
Differences in the ability of human T-cell lymphotropic virus type 1 (HTLV-1) and HTLV-2 tax to inhibit p53 function.
Journal of virology 2000;74(15):6866-74.
2000: Christophe Nicot; Renaud Mahieux; Shigeki Takemoto; Genoveffa Franchini
Bcl-X(L) is up-regulated by HTLV-I and HTLV-II in vitro and in ex vivo ATLL samples.
Blood 2000;96(1):275-81.
2000: Shigeki Takemoto; R Trovato; A Cereseto; Christophe Nicot; T Kislyakova; L Casareto; Thomas Waldmann; G Torelli; Genoveffa Franchini
p53 stabilization and functional impairment in the absence of genetic mutation or the alteration of the p14(ARF)-MDM2 loop in ex vivo and cultured adult T-cell leukemia/lymphoma cells.
Blood 2000;95(12):3939-44.
2000: Christophe Nicot; Renaud Mahieux; Rene Opavsky; A Cereseto; Linda Wolff; John N Brady; Genoveffa Franchini
HTLV-I Tax transrepresses the human c-Myb promoter independently of its interaction with CBP or p300.
Oncogene 2000;19(17):2155-64.
1999: A Cereseto; T Kislyakova; R Washington Parks; Christophe Nicot; Genoveffa Franchini
Differential response to genotoxic stress in immortalized or transformed human T-lymphotropic virus type I-infected T-cells.
The Journal of general virology 1999;80 ( Pt 7)():1575-81.
1998: JC Mulloy; T Kislyakova; A Cereseto; L Casareto; A LoMonico; Jake R Fullen; M V Lorenzi; Andrea Cara; Christophe Nicot; Chou-Zen Giam; Genoveffa Franchini
Human T-cell lymphotropic/leukemia virus type 1 Tax abrogates p53-induced cell cycle arrest and apoptosis through its CREB/ATF functional domain.
Journal of virology 1998;72(11):8852-60.
1998: Robert Harrod; Yong Tang; Christophe Nicot; H S Lu; A Vassilev; Yoshihiro Nakatani; Chou-Zen Giam
An exposed KID-like domain in human T-cell lymphotropic virus type 1 Tax is responsible for the recruitment of coactivators CBP/p300.
Molecular and cellular biology 1998;18(9):5052-61.
1998: Christophe Nicot; F Tie; Chou-Zen Giam
Cytoplasmic forms of human T-cell leukemia virus type 1 Tax induce NF-kappaB activation.
Journal of virology 1998;72(8):6777-84.