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Ian Nieduszynski

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Robert Lauder; Ian A Nieduszynski; Thomas N Huckerby; Ian H Sadler
Characterisation of oligosaccharides from the chondroitin/dermatan sulphates: (1)H and (13)C NMR studies of oligosaccharides generated by nitrous acid depolymerisation.
Robert Lauder; Thomas N Huckerby; Ian A Nieduszynski
Lectin affinity chromatography of articular cartilage fibromodulin: Some molecules have keratan sulphate chains exclusively capped by α(2-3)-linked sialic acid.
Leanne J Cooper; Adam J Bentley; Ian A Nieduszynski; Sheelan Talabani; Alan Thomson; Atsushi Utani; Hiroshi Shinkai; Nigel J Fullwood; Gavin M Brown
The role of dermatopontin in the stromal organization of the cornea.

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All Publications

2011: Robert Lauder; Ian A Nieduszynski; Thomas N Huckerby; Ian H Sadler
Characterisation of oligosaccharides from the chondroitin/dermatan sulphates: (1)H and (13)C NMR studies of oligosaccharides generated by nitrous acid depolymerisation.
Carbohydrate research 2011;346(14):2222-7.
2011: Robert Lauder; Thomas N Huckerby; Ian A Nieduszynski
Lectin affinity chromatography of articular cartilage fibromodulin: Some molecules have keratan sulphate chains exclusively capped by α(2-3)-linked sialic acid.
Glycoconjugate journal 2011;28(7):453-61.
2006: Leanne J Cooper; Adam J Bentley; Ian A Nieduszynski; Sheelan Talabani; Alan Thomson; Atsushi Utani; Hiroshi Shinkai; Nigel J Fullwood; Gavin M Brown
The role of dermatopontin in the stromal organization of the cornea.
Investigative ophthalmology & visual science 2006;47(8):3303-10.
2005: Thomas N Huckerby; Ian A Nieduszynski; Marcos Giannopoulos; Stephen D Weeks; Ian H Sadler; Robert Lauder
Characterization of oligosaccharides from the chondroitin/dermatan sulfates. 1H-NMR and 13C-NMR studies of reduced trisaccharides and hexasaccharides.
The FEBS journal 2005;272(24):6276-86.
2001: Robert Lauder; Thomas N Huckerby; Gavin M Brown; MT Bayliss; Ian A Nieduszynski
Age-related changes in the sulphation of the chondroitin sulphate linkage region from human articular cartilage aggrecan.
The Biochemical journal 2001;358(Pt 2):523-8.
2001: Thomas N Huckerby; Robert Lauder; Gavin M Brown; Ian A Nieduszynski; K Anderson; J Boocock; P L Sandall; S D Weeks
Characterization of oligosaccharides from the chondroitin sulfates. (1)H-NMR and (13)C-NMR studies of reduced disaccharides and tetrasaccharides.
European journal of biochemistry / FEBS 2001;268(5):1181-9.
2000: Robert Lauder; Thomas N Huckerby; Ian A Nieduszynski
Increased incidence of unsulphated and 4-sulphated residues in the chondroitin sulphate linkage region observed by high-pH anion-exchange chromatography.
The Biochemical journal 2000;347(Pt 2):339-48.
2000: Robert Lauder; Thomas N Huckerby; Ian A Nieduszynski
A fingerprinting method for chondroitin/dermatan sulfate and hyaluronan oligosaccharides.
Glycobiology 2000;10(4):393-401.
2000: D Lewis; Y Davies; Ian A Nieduszynski; F Lawrence; Andrew J Quantock; Richard E Bonshek; Nigel J Fullwood
Ultrastructural localization of sulfated and unsulfated keratan sulfate in normal and macular corneal dystrophy type I.
Glycobiology 2000;10(3):305-12.
1999: Thomas N Huckerby; Ian A Nieduszynski; MT Bayliss; Gavin M Brown
600 MHz NMR studies of human articular cartilage keratan sulfates.
European journal of biochemistry / FEBS 1999;266(3):1174-83.
1999: Y Davies; D Lewis; Nigel J Fullwood; Ian A Nieduszynski; B Marcyniuk; J Albon; Andrew B Tullo
Proteoglycans on normal and migrating human corneal endothelium.
Experimental eye research 1999;68(3):303-11.
1999: K M Whitham; J L Hadley; H G Morris; S M Andrew; Ian A Nieduszynski; Gavin M Brown
An improved method for the structural profiling of keratan sulfates: analysis of keratan sulfates from brain and ovarian tumors.
Glycobiology 1999;9(3):285-91.
1998: Thomas N Huckerby; Robert Lauder; Ian A Nieduszynski
Structure determination for octasaccharides derived from the carbohydrate-protein linkage region of chondroitin sulphate chains in the proteoglycan aggrecan from bovine articular cartilage.
European journal of biochemistry / FEBS 1998;258(2):669-76.
1998: Gavin M Brown; Thomas N Huckerby; MT Bayliss; Ian A Nieduszynski
Human aggrecan keratan sulfate undergoes structural changes during adolescent development.
The Journal of biological chemistry 1998;273(41):26408-14.
1998: G Bairaktaris; D Lewis; Nigel J Fullwood; Ian A Nieduszynski; B Marcyniuk; Andrew J Quantock; AE Ridgway
An ultrastructural investigation into proteoglycan distribution in human corneas.
Cornea 1998;17(4):396-402.
1998: Thomas N Huckerby; G H Tai; Ian A Nieduszynski
Oligosaccharides derived by endo-beta-galactosidase digestion of bovine corneal keratan sulphate--characterisation of tetrasaccharides with incomplete sulphation and containing unsulphated N-acetylglucosamine residues.
European journal of biochemistry / FEBS 1998;253(2):499-506.
1998: Robert Lauder; Thomas N Huckerby; Ian A Nieduszynski; A H Plaas
Age-related changes in the structure of the keratan sulphate chains attached to fibromodulin isolated from articular cartilage.
The Biochemical journal 1998;330 ( Pt 2)():753-7.
1998: Thomas N Huckerby; Gavin M Brown; Ian A Nieduszynski
13C-NMR spectroscopy of keratan sulphates--assignments for five sialylated pentasaccharides derived from the non-reducing chain termini of bovine articular cartilage keratan sulphate by keratanase II digestion.
European journal of biochemistry / FEBS 1998;251(3):991-7.
1997: G H Tai; Ian A Nieduszynski; Nigel J Fullwood; Thomas N Huckerby
Human corneal keratan sulfates.
The Journal of biological chemistry 1997;272(45):28227-31.
1997: Robert Lauder; Thomas N Huckerby; Ian A Nieduszynski
The structure of the keratan sulphate chains attached to fibromodulin from human articular cartilage.
Glycoconjugate journal 1997;14(5):651-60.
1997: Y Davies; Nigel J Fullwood; B Marcyniuk; Richard E Bonshek; Andrew B Tullo; Ian A Nieduszynski
Keratan sulphate in the trabecular meshwork and cornea.
Current eye research 1997;16(7):677-86.
1996: Robert Lauder; Thomas N Huckerby; Ian A Nieduszynski
The structure of the keratan sulphate chains attached to fibromodulin isolated from articular cartilage.
European journal of biochemistry / FEBS 1996;242(2):402-9.
1996: Gavin M Brown; Thomas N Huckerby; B L Abram; Ian A Nieduszynski
Characterization of a non-reducing terminal fragment from bovine articular cartilage keratan sulphates containing alpha(2-3)-linked sialic acid and alpha(1-3)-linked fucose. A sulphated variant of the VIM-2 epitope.
The Biochemical journal 1996;319 ( Pt 1)():137-41.
1996: G H Tai; Thomas N Huckerby; Ian A Nieduszynski
Multiple non-reducing chain termini isolated from bovine corneal keratan sulfates.
The Journal of biological chemistry 1996;271(38):23535-46.
1996: Nigel J Fullwood; Y Davies; Ian A Nieduszynski; B Marcyniuk; AE Ridgway; Andrew J Quantock
Cell surface-associated keratan sulfate on normal and migrating corneal endothelium.
Investigative ophthalmology & visual science 1996;37(7):1256-70.
1995: Robert Lauder; Thomas N Huckerby; Ian A Nieduszynski
The structure of the keratan sulphate chains attached to fibromodulin isolated from bovine tracheal cartilage: oligosaccharides generated by keratanase II digestion.
Glycoconjugate journal 1995;12(5):651-9.
1995: Thomas N Huckerby; Gavin M Brown; Ian A Nieduszynski
13C-NMR spectroscopy of keratan sulphates. Assignments for four poly(N-acetyllactosamine)-repeat-sequence tetrasaccharides derived from bovine articular cartilage keratan sulphate by keratanase II digestion.
European journal of biochemistry / FEBS 1995;231(3):779-83.
1995: Thomas N Huckerby; J M Dickenson; Gavin M Brown; Ian A Nieduszynski
Keratanase digestion of keratan sulphates: characterization of large oligosaccharides from the N-acetyllactosamine repeat sequence and from the non-reducing terminal chain caps.
Biochimica et biophysica acta 1995;1244(1):17-29.
1995: Gavin M Brown; Ian A Nieduszynski; H G Morris; B L Abram; Thomas N Huckerby; J A Block
Skeletal keratan sulphate structural analysis using keratanase II digestion followed by high-performance anion-exchange chromatography.
Glycobiology 1995;5(3):311-7.
1995: Thomas N Huckerby; Gavin M Brown; J M Dickenson; Ian A Nieduszynski
Spectroscopic characterisation of disaccharides derived from keratan sulfates.
European journal of biochemistry / FEBS 1995;229(1):119-31.
1994: Robert Lauder; Thomas N Huckerby; Ian A Nieduszynski
Structure of the keratan sulphate chains attached to fibromodulin isolated from bovine tracheal cartilage. Oligosaccharides generated by keratanase digestion.
The Biochemical journal 1994;302 ( Pt 2)():417-23.
1994: Gavin M Brown; Thomas N Huckerby; Ian A Nieduszynski
Oligosaccharides derived by keratanase II digestion of bovine articular cartilage keratan sulphates.
European journal of biochemistry / FEBS 1994;224(2):281-308.
1994: Gavin M Brown; Thomas N Huckerby; H G Morris; B L Abram; Ian A Nieduszynski
Oligosaccharides derived from bovine articular cartilage keratan sulfates after keratanase II digestion: implications for keratan sulfate structural fingerprinting.
Biochemistry 1994;33(16):4836-46.
1994: G H Tai; Thomas N Huckerby; Ian A Nieduszynski
600 MHz 1H NMR study of a fucose-containing heptasaccharide derived from a keratanase digestion of bovine articular cartilage keratan sulphate.
Carbohydrate research 1994;255():303-9.
1993: G H Tai; Thomas N Huckerby; Ian A Nieduszynski
N.m.r. spectroscopic studies of fucose-containing oligosaccharides derived from keratanase digestion of articular cartilage keratan sulphates. Influence of fucose residues on keratanase cleavage.
The Biochemical journal 1993;291 ( Pt 3)():889-94.
1992: Gavin M Brown; Thomas N Huckerby; H G Morris; Ian A Nieduszynski
Degradation of articular cartilage keratan sulphates using hydrazinolysis and nitrous acid. Environment of fucose residues.
The Biochemical journal 1992;286 ( Pt 1)():235-41.
1992: G H Tai; H G Morris; Gavin M Brown; Thomas N Huckerby; Ian A Nieduszynski
A sub-population of keratan sulphates derived from bovine articular cartilage is capped with alpha(2-6)-linked N-acetylneuraminic acid residues. Affinity chromatography using immobilized Sambucus nigra lectin and characterization using 1H n.m.r. spectroscopy.
The Biochemical journal 1992;286 ( Pt 1)():231-4.
1992: J M Dickenson; Thomas N Huckerby; Ian A Nieduszynski
Skeletal keratan sulphate chains isolated from bovine intervertebral disc may terminate in alpha(2----6)-linked N-acetylneuraminic acid.
The Biochemical journal 1992;282 ( Pt 1)():267-71.
1991: J M Dickenson; Thomas N Huckerby; Ian A Nieduszynski
A non-reducing terminal fragment from tracheal cartilage keratan sulphate chains contains alpha (2-3)-linked N-acetylneuraminic acid.
The Biochemical journal 1991;278 ( Pt 3)():779-85.
1991: Thomas N Huckerby; Ian A Nieduszynski; Gavin M Brown; G H Cockin
A full assignment of proton resonances for an alpha(1-3)-linked fucose residue in keratan sulphate from bovine articular cartilage.
Glycoconjugate journal 1991;8(1):39-44.
1991: G H Tai; Gavin M Brown; H G Morris; Thomas N Huckerby; Ian A Nieduszynski
Fucose content of keratan sulphates from bovine articular cartilage.
The Biochemical journal 1991;273(Pt 2)():307-10.
1990: J M Dickenson; H G Morris; Ian A Nieduszynski; Thomas N Huckerby
Skeletal keratan sulfate chain molecular weight calibration by high-performance gel-permeation chromatography.
Analytical biochemistry 1990;190(2):271-5.
1990: Ian A Nieduszynski; Thomas N Huckerby; J M Dickenson; Gavin M Brown; G H Tai; H G Morris; S Eady
There are two major types of skeletal keratan sulphates.
The Biochemical journal 1990;271(1):243-5.
1990: Ian A Nieduszynski; Thomas N Huckerby; J M Dickenson; Gavin M Brown; G H Tai; M T Bayliss
Structural aspects of skeletal keratan sulphates.
Biochemical Society transactions 1990;18(5):792-3.
1990: J M Dickenson; Thomas N Huckerby; Ian A Nieduszynski
Two linkage-region fragments isolated from skeletal keratan sulphate contain a sulphated N-acetylglucosamine residue.
The Biochemical journal 1990;269(1):55-9.
1989: David J Thornton; H G Morris; G H Cockin; Thomas N Huckerby; Ian A Nieduszynski; Ingemar Carlstedt; T E Hardingham; A Ratcliffe
Structural and immunological studies of keratan sulphates from mature bovine articular cartilage.
The Biochemical journal 1989;260(1):277-82.
1989: P N Sanderson; Thomas N Huckerby; Ian A Nieduszynski
Chondroitinase ABC digestion of dermatan sulphate. N.m.r. spectroscopic characterization of the oligo- and poly-saccharides.
The Biochemical journal 1989;257(2):347-54.
1989: David J Thornton; H G Morris; G H Cockin; Thomas N Huckerby; Ian A Nieduszynski
Structural studies of two populations of keratan sulphate chains from mature bovine articular cartilage.
Glycoconjugate journal 1989;6(2):209-18.
1987: David J Thornton; John K Sheehan; Ian A Nieduszynski
A study of the interaction between cartilage proteoglycan and link protein.
The Biochemical journal 1987;248(3):943-51.
1987: M E Bassett; David J Thornton; John K Sheehan; Ian A Nieduszynski
An enzyme-linked immunosorbent assay (ELISA) of denatured cartilage link protein.
Biochimica et biophysica acta 1987;925(3):347-55.
1987: P N Sanderson; Thomas N Huckerby; Ian A Nieduszynski
Conformational equilibria of alpha-L-iduronate residues in disaccharides derived from heparin.
The Biochemical journal 1987;243(1):175-81.
1986: David J Thornton; Ian A Nieduszynski; K Oates; John K Sheehan
Electron-microscopic and electrophoretic studies of bovine femoral-head cartilage proteoglycan fractions.
The Biochemical journal 1986;240(1):41-8.
1986: Thomas N Huckerby; P N Sanderson; Ian A Nieduszynski
N.m.r. studies of oligosaccharides obtained by degradation of bovine lung heparin with nitrous acid.
Carbohydrate research 1986;154():15-27.
1986: G H Cockin; Thomas N Huckerby; Ian A Nieduszynski
High-field n.m.r. studies of keratan sulphates. 1H and 13C assignments of keratan sulphate from shark cartilage.
The Biochemical journal 1986;236(3):921-4.
1985: Thomas N Huckerby; P N Sanderson; Ian A Nieduszynski
N.m.r. studies of the disulphated disaccharide obtained by degradation of bovine lung heparin with nitrous acid.
Carbohydrate research 1985;138(2):199-206.
1984: P N Sanderson; Thomas N Huckerby; Ian A Nieduszynski
Very-high-field n.m.r. studies of bovine lung heparan sulphate tetrasaccharides produced by nitrous acid deaminative cleavage. Determination of saccharide sequence, uronate composition and degrees of sulphation.
The Biochemical journal 1984;223(2):495-505.
1983: M Lyon; Ian A Nieduszynski
A study of equilibrium binding of link protein to hyaluronate.
The Biochemical journal 1983;213(2):445-50.
1983: M Lyon; J Greenwood; John K Sheehan; Ian A Nieduszynski
Isolation and characterization of high-buoyant-density proteoglycans from bovine femoral-head cartilage.
The Biochemical journal 1983;213(2):355-62.
1983: P N Sanderson; Ian A Nieduszynski; Thomas N Huckerby
Very-high-field n.m.r. studies of bovine lung heparan sulphate oligosaccharides produced by nitrous acid deaminative cleavage. 13C-n.m.r. study of methylene resonances: degree and positions of C-6 sulphation.
The Biochemical journal 1983;211(3):677-82.
1981: J Denton; W E Lewis; Ian A Nieduszynski; C F Phelps
Fractionation of heparin using antithrombin III reversibly bound to concanavalin A-sepharose.
Analytical biochemistry 1981;118(2):388-91.
1981: Ian A Nieduszynski; John K Sheehan
Equilibrium and kinetic studies of the interaction between cartilage proteoglycan and hyaluronate.
Biochemical Society transactions 1981;9(6):502-4.
1981: L Cöster; Lars-Ake Fransson; John K Sheehan; Ian A Nieduszynski; C F Phelps
Self-association of dermatan sulphate proteoglycans from bovine sclera.
The Biochemical journal 1981;197(2):483-90.
1980: Lars-Ake Fransson; Birgitta Havsmark; Ian A Nieduszynski; Thomas N Huckerby
Interaction between heparan sulphate chains. II. Structural characterization of iduronate- and glucuronate-containing sequences in aggregating chains.
Biochimica et biophysica acta 1980;633(1):95-104.
1980: Ian A Nieduszynski; John K Sheehan; C F Phelps; T E Hardingham; H Muir
Equilibrium-binding studies of pig laryngeal cartilage proteoglycans with hyaluronate oligosaccharide fractions.
The Biochemical journal 1980;185(1):107-14.