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Mogens Nielsen

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Jakob Nilsson; Tommy Liljefors; Mogens Nielsen; Elsebet Østergaard Nielsen; Olov Sterner
3-Alkyl- and 3-amido-isothiazoloquinolin-4-ones as ligands for the benzodiazepine site of GABA(A) receptors.
Jakob Nilsson; Ritha Gidlöf; Elsebet Ø Nielsen; Tommy Liljefors; Mogens Nielsen; Olov Sterner
Triazoloquinazolinediones as novel high affinity ligands for the benzodiazepine site of GABA(A) receptors.
Jakob Nilsson; Elsebet Østergaard Nielsen; Tommy Liljefors; Mogens Nielsen; Olov Sterner
Azaflavones compared to flavones as ligands to the benzodiazepine binding site of brain GABA(A) receptors.

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All Publications

2012: Jakob Nilsson; Tommy Liljefors; Mogens Nielsen; Elsebet Østergaard Nielsen; Olov Sterner
3-Alkyl- and 3-amido-isothiazoloquinolin-4-ones as ligands for the benzodiazepine site of GABA(A) receptors.
Bioorganic chemistry 2012;40(1):125-30.
2011: Jakob Nilsson; Ritha Gidlöf; Elsebet Ø Nielsen; Tommy Liljefors; Mogens Nielsen; Olov Sterner
Triazoloquinazolinediones as novel high affinity ligands for the benzodiazepine site of GABA(A) receptors.
Bioorganic & medicinal chemistry 2011;19(1):111-21.
2008: Jakob Nilsson; Elsebet Østergaard Nielsen; Tommy Liljefors; Mogens Nielsen; Olov Sterner
Azaflavones compared to flavones as ligands to the benzodiazepine binding site of brain GABA(A) receptors.
Bioorganic & medicinal chemistry letters 2008;18(21):5713-6.
2008: Erik Lager; Jakob Nilsson; Elsebet Østergaard Nielsen; Mogens Nielsen; Tommy Liljefors; Olov Sterner
Affinity of 3-acyl substituted 4-quinolones at the benzodiazepine site of GABA(A) receptors.
Bioorganic & medicinal chemistry 2008;16(14):6936-48.
2006: Erik Lager; Pierre Andersson; Jakob Nilsson; Ingrid Pettersson; Elsebet Ø Nielsen; Mogens Nielsen; Olov Sterner; Tommy Liljefors
4-quinolone derivatives: high-affinity ligands at the benzodiazepine site of brain GABA A receptors. synthesis, pharmacology, and pharmacophore modeling.
Journal of medicinal chemistry 2006;49(8):2526-33.
2004: Pia Kahnberg; Michael H Howard; Tommy Liljefors; Mogens Nielsen; Elsebet Ø Nielsen; Olov Sterner; Ingrid Pettersson
The use of a pharmacophore model for identification of novel ligands for the benzodiazepine binding site of the GABAA receptor.
Journal of molecular graphics & modelling 2004;23(3):253-61.
2002: Pia Kahnberg; Erik Lager; Celia Rosenberg; Jette Schougaard; Linda Camet; Olov Sterner; Elsebet Østergaard Nielsen; Mogens Nielsen; Tommy Liljefors
Refinement and evaluation of a pharmacophore model for flavone derivatives binding to the benzodiazepine site of the GABA(A) receptor.
Journal of medicinal chemistry 2002;45(19):4188-201.
2001: J Ai; X Wang; Mogens Nielsen
Honokiol and magnolol selectively interact with GABAA receptor subtypes in vitro.
Pharmacology 2001;63(1):34-41.
2000: J Ai; X Wang; H Wahe; Z T Fomum; Olov Sterner; Mogens Nielsen; Michael-Robin Witt
2-Oxo-2H-Pyrimido[2,1-b]benzothiazoles inhibit brain benzodiazepine receptor binding in vitro.
Pharmacology 2000;60(4):175-8.
1999: RF Squires; J Ai; Michael-Robin Witt; Pia Kahnberg; E Saederup; O Sterner; Mogens Nielsen
Honokiol and magnolol increase the number of [3H] muscimol binding sites three-fold in rat forebrain membranes in vitro using a filtration assay, by allosterically increasing the affinities of low-affinity sites.
Neurochemical research 1999;24(12):1593-602.
1999: K Dekermendjian; Pia Kahnberg; Michael-Robin Witt; Olov Sterner; Mogens Nielsen; Tommy Liljefors
Structure-activity relationships and molecular modeling analysis of flavonoids binding to the benzodiazepine site of the rat brain GABA(A) receptor complex.
Journal of medicinal chemistry 1999;42(21):4343-50.
1999: SE Westh-Hansen; Michael-Robin Witt; K Dekermendjian; Tommy Liljefors; PB Rasmussen; Mogens Nielsen
Arginine residue 120 of the human GABAA receptor alpha 1, subunit is essential for GABA binding and chloride ion current gating.
Neuroreport 1999;10(11):2417-21.
1999: Michael-Robin Witt; C F Poulsen; B Lükensmejer; SE Westh-Hansen; Junichi Nabekura; Norio Akaike; Mogens Nielsen
Structural requirements for the interaction of unsaturated free fatty acids with recombinant human GABAA receptor complexes.
Annals of the New York Academy of Sciences 1999;868():697-700.
1997: J Karle; P Laudrup; Frank Sams-Dodd; Jens D Mikkelsen; Mogens Nielsen
Differential changes in induced seizures after hippocampal treatment of rats with an antisense oligodeoxynucleotide to the GABA(A) receptor gamma2 subunit.
European journal of pharmacology 1997;340(2-3):153-60.
1997: Jesper Karle; Michael-Robin Witt; Mogens Nielsen
The use of in vivo antisense oligonucleotide technology for the investigation of brain GABA receptors.
Neurochemistry international 1997;31(3):437-46.
1997: Jesper Karle; Michael-Robin Witt; Mogens Nielsen
Diazepam protects against rat hippocampal neuronal cell death induced by antisense oligodeoxynucleotide to GABA(A) receptor gamma2 subunit.
Brain research 1997;765(1):21-9.
1997: SE Westh-Hansen; K Noguchi; Michael-Robin Witt; Y Murai; Mogens Nielsen; Norio Akaike
Effects of 5-(4-piperidyl) isoxazol-3-ol (4-PIOL), a GABA(A) receptor partial agonist, on recombinant human GABA(A) receptors.
Neuroscience letters 1997;230(1):45-8.
1997: SE Westh-Hansen; PB Rasmussen; Sven Hastrup; Junichi Nabekura; K Noguchi; Norio Akaike; Michael-Robin Witt; Mogens Nielsen
Decreased agonist sensitivity of human GABA(A) receptors by an amino acid variant, isoleucine to valine, in the alpha1 subunit.
European journal of pharmacology 1997;329(2-3):253-7.
1997: Ola Bergendorff; K Dekermendjian; Mogens Nielsen; R Shan; R Witt; J Ai; Olov Sterner
Furanocoumarins with affinity to brain benzodiazepine receptors in vitro.
Phytochemistry 1997;44(6):1121-4.
1996: K Dekermendjian; J Ai; Mogens Nielsen; Olov Sterner; R Shan; Michael-Robin Witt
Characterisation of the furanocoumarin phellopterin as a rat brain benzodiazepine receptor partial agonist in vitro.
Neuroscience letters 1996;219(3):151-4.
1996: O Gredal; B Pakkenberg; Mogens Nielsen
Muscarinic, N-methyl-D-aspartate (NMDA) and benzodiazepine receptor binding sites in cortical membranes from amyotrophic lateral sclerosis patients.
Journal of the neurological sciences 1996;143(1-2):121-5.
1996: Michael-Robin Witt; SE Westh-Hansen; PB Rasmussen; Sven Hastrup; Mogens Nielsen
Unsaturated free fatty acids increase benzodiazepine receptor agonist binding depending on the subunit composition of the GABAA receptor complex.
Journal of neurochemistry 1996;67(5):2141-5.
1996: O Gredal; Michael-Robin Witt; K Dekermendjian; S E Møller; Mogens Nielsen
Cerebrospinal fluid from amyotrophic lateral sclerosis has no effect on intracellular free calcium in cultured cortical neurons.
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1996;29(2-3):141-52.
1996: X L Shen; Michael-Robin Witt; Mogens Nielsen; Olov Sterner
Inhibition of [3H] flunitrazepam binding to rat brain membranes in vitro by puerarin and daidzein.
Yao xue xue bao = Acta pharmaceutica Sinica 1996;31(1):59-62.
1995: J Karle; Michael-Robin Witt; Mogens Nielsen
Antisense oligonucleotide to GABAA receptor gamma 2 subunit induces loss of neurones in rat hippocampus.
Neuroscience letters 1995;202(1-2):97-100.
1995: Mogens Nielsen; Michael-Robin Witt; Bjarke Ebert; P Krogsgaard-Larsen
Thiomuscimol, a new photoaffinity label for the GABAA receptor.
European journal of pharmacology 1995;289(1):109-12.
1995: M Andersson; Ola Bergendorff; Mogens Nielsen; Olov Sterner; R Witt; J Ai; A Lu; A M Wang
Inhibition of kainic acid binding to glutamate receptors by extracts of Gastrodia.
Phytochemistry 1995;38(4):835-6.
1994: Michael-Robin Witt; K Dekermendjian; A Frandsen; A Schousboe; Mogens Nielsen
Complex correlation between excitatory amino acid-induced increase in the intracellular Ca2+ concentration and subsequent loss of neuronal function in individual neocortical neurons in culture.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(25):12303-7.
1994: Michael-Robin Witt; O Gredal; K Dekermendjian; M Undén; Mogens Nielsen
Calcium homeostasis in fibroblasts from patients with amyotrophic lateral sclerosis.
Journal of the neurological sciences 1994;126(2):206-12.
1994: X L Shen; Mogens Nielsen; Michael-Robin Witt; Olov Sterner; Ola Bergendorff; M Khayyal
Inhibition of [methyl-3H]diazepam binding to rat brain membranes in vitro by dinatin and skrofulein.
Zhongguo yao li xue bao = Acta pharmacologica Sinica 1994;15(5):385-8.
1994: X L Shen; Michael-Robin Witt; K Dekermendjian; Mogens Nielsen
Isolation and identification of tetrahydrocolumbamine as a dopamine receptor ligand from Polygala tenuifolia Willd.
Yao xue xue bao = Acta pharmaceutica Sinica 1994;29(12):887-90.