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Onni Niemelä

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Joanna Danielsson; Päivikki Kangastupa; Tiina Laatikainen; Mauri Aalto; Onni Niemelä
Dose- and Gender-dependent Interactions between Coffee Consumption and Serum GGT Activity in Alcohol Consumers.
Antti J Tikkakoski; Jani Viitala; Anna Tahvanainen; Antti Haring; Mika A P Kähönen; Tiit Kööbi; Jenni K Koskela; Miia H Leskinen; Jukka T Mustonen; Onni Niemelä; Ilkka H Pörsti
Hemodynamic alterations in hypertensive patients at rest and during passive head-up tilt.
B I Nwaru; Juha Pekkanen; Olli Simell; H-M Takkinen; H Tuomi; Riitta Veijola; Suvi Ahonen; Maijaliisa Erkkola; Anna-Maija Haapala; Heikki Hyöty; Jorma Ilonen; Minna Kaila; Mike Kenward; Juha Kere; Mikael Knip; Riitta Lahesmaa; Onni Niemelä; Suvi M Virtanen
Introduction of complementary foods in infancy and atopic sensitization at the age of 5 years: timing and food diversity in a Finnish birth cohort.

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2013: Joanna Danielsson; Päivikki Kangastupa; Tiina Laatikainen; Mauri Aalto; Onni Niemelä
Dose- and Gender-dependent Interactions between Coffee Consumption and Serum GGT Activity in Alcohol Consumers.
Alcohol and alcoholism (Oxford, Oxfordshire) 2013;48(3):303-7.
2013: Antti J Tikkakoski; Jani Viitala; Anna Tahvanainen; Antti Haring; Mika A P Kähönen; Tiit Kööbi; Jenni K Koskela; Miia H Leskinen; Jukka T Mustonen; Onni Niemelä; Ilkka H Pörsti
Hemodynamic alterations in hypertensive patients at rest and during passive head-up tilt.
Journal of hypertension 2013;31(5):906-15.
2013: B I Nwaru; Juha Pekkanen; Olli Simell; H-M Takkinen; H Tuomi; Riitta Veijola; Suvi Ahonen; Maijaliisa Erkkola; Anna-Maija Haapala; Heikki Hyöty; Jorma Ilonen; Minna Kaila; Mike Kenward; Juha Kere; Mikael Knip; Riitta Lahesmaa; Onni Niemelä; Suvi M Virtanen
Introduction of complementary foods in infancy and atopic sensitization at the age of 5 years: timing and food diversity in a Finnish birth cohort.
Allergy 2013;68(4):507-16.
2013: Juha Rainio; Heidi Tuomi; Sanna Ahola; Anders Helander; Päivikki Kangastupa; Pekka J Karhunen; Johanna Kultti; Onni Niemelä
Immunoassay for ethyl glucuronide in vitreous humor: a new tool for postmortem diagnostics of alcohol use.
Forensic science international 2013;226(1-3):261-5.
2013: Bright I Nwaru; Juha Pekkanen; Olli Simell; Hanna-Mari Takkinen; Riitta Veijola; Suvi Ahonen; Maijaliisa Erkkola; Anna-Maija Haapala; Heikki Hyöty; Jorma Ilonen; Minna Kaila; Mike Kenward; Juha Kere; Mikael Knip; Riitta Lahesmaa; Onni Niemelä; Suvi M Virtanen
Timing of infant feeding in relation to childhood asthma and allergic diseases.
The Journal of allergy and clinical immunology 2013;131(1):78-86.
2012: Joanna Tynjälä; Mauri Aalto; Päivikki Kangastupa; Tiina Laatikainen; Onni Niemelä
Effect of age and gender on the relationship between alcohol consumption and serum GGT: time to recalibrate goals for normal ranges.
Alcohol and alcoholism (Oxford, Oxfordshire) 2012;47(5):558-62.
2012: Pauli Karhapää; M Kastarinen; Jukka Mustonen; Onni Niemelä; J Pihlajamäki; Ilkka Pörsti; H Tuomi; J Kuusisto
Glomerular filtration rate and parathyroid hormone are associated with 1,25-dihydroxyvitamin D in men without chronic kidney disease.
Journal of internal medicine 2012;271(6):573-80.
2012: Arttu Eräranta; Meng Fan; Jenni Koskela; Päivi Lakkisto; Jukka Mustonen; Onni Niemelä; Jyrki Parkkinen; Asko Riutta; Ilkka Tikkanen; Ilkka Pörsti
Dietary phosphate binding and loading alter kidney angiotensin-converting enzyme mRNA and protein content in 5/6 nephrectomized rats.
American journal of nephrology 2012;35(5):401-8.
2011: Anna Passoja; Taina Raunio; Olli Vainio; Pirjo Hedberg; Liisa Hiltunen; Riitta Karttunen; Matti L E Knuuttila; Onni Niemelä; Tellervo Tervonen
Serum high-density lipoprotein cholesterol level associated with the extent of periodontal inflammation in type 1 diabetic subjects.
Journal of clinical periodontology 2011;38(12):1071-7.
2011: Anna Passoja; Taina Raunio; Olli Vainio; Pirjo Hedberg; Liisa Hiltunen; Riitta Karttunen; Matti L E Knuuttila; Onni Niemelä; Tellervo Tervonen
Serum interleukin-6 may modulate periodontal inflammation in type 1 diabetic subjects.
Journal of clinical periodontology 2011;38(8):687-93.
2010: P Karhapää; J Pihlajamäki; Ilkka Pörsti; M Kastarinen; Jukka Mustonen; Onni Niemelä; J Kuusisto
Diverse associations of 25-hydroxyvitamin D and 1,25-dihydroxy-vitamin D with dyslipidaemias.
Journal of internal medicine 2010;268(6):604-10.
2010: Anna Passoja; Ilkka Puijola; Matti L E Knuuttila; Onni Niemelä; Riitta Karttunen; Taina Raunio; Tellervo Tervonen
Serum levels of interleukin-10 and tumour necrosis factor-α in chronic periodontitis.
Journal of clinical periodontology 2010;37(10):881-7.
2010: Onni Niemelä; Päivikki Alatalo
Biomarkers of alcohol consumption and related liver disease.
Scandinavian journal of clinical and laboratory investigation 2010;70(5):305-12.
2010: Päivikki Alatalo; Heidi Koivisto; Johanna Kultti; Risto Bloigu; Onni Niemelä
Evaluation of reference intervals for biomarkers sensitive to alcohol consumption, excess body weight and oxidative stress.
Scandinavian journal of clinical and laboratory investigation 2010;70(2):104-11.
2009: Venla Kurra; Arttu Eräranta; Pasi Jolma; Tuija I Vehmas; Asko Riutta; Eeva Moilanen; Anna Tahvanainen; Jarkko Kalliovalkama; Onni Niemelä; Juhani Myllymäki; Jukka Mustonen; Ilkka Pörsti
Hyperuricemia, oxidative stress, and carotid artery tone in experimental renal insufficiency.
American journal of hypertension 2009;22(9):964-70.
2009: Kati Kaartinen; Onni Niemelä; Jaana Syrjänen; Päivikki Alatalo; Ilkka Pörsti; Aimo Harmoinen; Amos Pasternack; Heini Huhtala; Jukka Mustonen
IgA immune responses against acetaldehyde adducts and biomarkers of alcohol consumption in patients with IgA glomerulonephritis.
Alcoholism, clinical and experimental research 2009;33(7):1231-7.
2009: Päivikki I Alatalo; Heidi M Koivisto; Johanna P Hietala; Risto Bloigu; Onni Niemelä
Gender-dependent impacts of body mass index and moderate alcohol consumption on serum uric acid--an index of oxidant stress status?
Free radical biology & medicine 2009;46(8):1233-8.
2009: Päivikki Alatalo; Heidi Koivisto; Katri Puukka; Johanna Hietala; Petra Anttila; Risto Bloigu; Onni Niemelä
Biomarkers of liver status in heavy drinkers, moderate drinkers and abstainers.
Alcohol and alcoholism (Oxford, Oxfordshire) 2009;44(2):199-203.
2008: Päivikki I Alatalo; Heidi M Koivisto; Johanna Hietala; Katri S Puukka; Risto Bloigu; Onni Niemelä
Effect of moderate alcohol consumption on liver enzymes increases with increasing body mass index.
The American journal of clinical nutrition 2008;88(4):1097-103.
2008: Arttu Eräranta; Venla Kurra; Anna Tahvanainen; Tuija I Vehmas; Peeter Kööbi; Päivi Lakkisto; Ilkka Tikkanen; Onni Niemelä; Jukka Mustonen; Ilkka Pörsti
Oxonic acid-induced hyperuricemia elevates plasma aldosterone in experimental renal insufficiency.
Journal of hypertension 2008;26(8):1661-8.
2008: Matteo Vidali; Johanna Hietala; Giuseppa Occhino; Alessandra Ivaldi; Salvatore Sutti; Onni Niemelä; Emanuele Albano
Immune responses against oxidative stress-derived antigens are associated with increased circulating tumor necrosis factor-alpha in heavy drinkers.
Free radical biology & medicine 2008;45(3):306-11.
2008: Markus Färkkilä; Henna Rautiainen; Päivi Kärkkäinen; Anna-Liisa Karvonen; Heimo Nurmi; Onni Niemelä
Serological markers for monitoring disease progression in noncirrhotic primary biliary cirrhosis on ursodeoxycholic acid therapy.
Liver international : official journal of the International Association for the Study of the Liver 2008;28(6):787-97.
2008: Saman Warnakulasuriya; Seppo Parkkila; Toru Nagao; Victor R Preedy; Markku Pasanen; Heidi Koivisto; Onni Niemelä
Demonstration of ethanol-induced protein adducts in oral leukoplakia (pre-cancer) and cancer.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2008;37(3):157-65.
2008: Heidi Koivisto; Johanna Hietala; Petra Anttila; Onni Niemelä
Co-occurrence of IgA antibodies against ethanol metabolites and tissue transglutaminase in alcohol consumers: correlation with proinflammatory cytokines and markers of fibrogenesis.
Digestive diseases and sciences 2008;53(2):500-5.
2008: Emmanouil Karavalakis; Arttu Eräranta; Tuija I Vehmas; Jenni K Koskela; Peeter Kööbi; Jukka Mustonen; Onni Niemelä; Jaana Rysä; Heikki Ruskoaho; Ilkka Pörsti
Paricalcitol treatment and arterial tone in experimental renal insufficiency.
Nephron. Experimental nephrology 2008;109(3):e84-93.
2007: J M Repo; Immo Rantala; Teemu Honkanen; Jukka Mustonen; Peeter Kööbi; Anna Tahvanainen; Onni Niemelä; Ilkka Tikkanen; Jaana Rysä; Heikki Ruskoaho; Ilkka Pörsti
Paricalcitol aggravates perivascular fibrosis in rats with renal insufficiency and low calcitriol.
Kidney international 2007;72(8):977-84.
2007: Heidi Koivisto; Johanna Hietala; Onni Niemelä
An inverse relationship between markers of fibrogenesis and collagen degradation in patients with or without alcoholic liver disease.
The American journal of gastroenterology 2007;102(4):773-9.
2007: Kati Kaartinen; Jaana Syrjänen; Ilkka Pörsti; Aimo Harmoinen; Amos Pasternack; Heini Huhtala; Onni Niemelä; Jukka Mustonen
Insulin resistance and the progression of IgA glomerulonephritis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2007;22(3):778-83.
2007: Onni Niemelä
Biomarkers in alcoholism.
Clinica chimica acta; international journal of clinical chemistry 2007;377(1-2):39-49.
2007: Katri Puukka; Johanna Hietala; Heidi Koivisto; Petra Anttila; Risto Bloigu; Onni Niemelä
Obesity and the clinical use of serum GGT activity as a marker of heavy drinking.
Scandinavian journal of clinical and laboratory investigation 2007;67(5):480-8.
2007: Onni Niemelä
Acetaldehyde adducts in circulation.
Novartis Foundation symposium 2007;285():183-92; discussion 193-7.
2006: Johanna Hietala; Heidi Koivisto; Jaana Latvala; Petra Anttila; Onni Niemelä
IgAs against acetaldehyde-modified red cell protein as a marker of ethanol consumption in male alcoholic subjects, moderate drinkers, and abstainers.
Alcoholism, clinical and experimental research 2006;30(10):1693-8.
2006: Peeter Kööbi; Tuija I Vehmas; Pasi Jolma; Jarkko Kalliovalkama; Meng Fan; Onni Niemelä; Heikki Saha; Mika Kähönen; Pauli Ylitalo; Jaana Rysä; Heikki Ruskoaho; Ilkka Pörsti
High-calcium vs high-phosphate intake and small artery tone in advanced experimental renal insufficiency.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2006;21(10):2754-61.
2006: Katri Puukka; Johanna Hietala; Heidi Koivisto; Petra Anttila; Risto Bloigu; Onni Niemelä
Age-related changes on serum ggt activity and the assessment of ethanol intake.
Alcohol and alcoholism (Oxford, Oxfordshire) 2006;41(5):522-7.
2006: Johanna Hietala; Heidi Koivisto; Petra Anttila; Onni Niemelä
Comparison of the combined marker GGT-CDT and the conventional laboratory markers of alcohol abuse in heavy drinkers, moderate drinkers and abstainers.
Alcohol and alcoholism (Oxford, Oxfordshire) 2006;41(5):528-33.
2006: Katri Puukka; Johanna Hietala; Heidi Koivisto; Petra Anttila; Risto Bloigu; Onni Niemelä
Additive effects of moderate drinking and obesity on serum gamma-glutamyl transferase activity.
The American journal of clinical nutrition 2006;83(6):1351-4; quiz 1448-9.
2006: Jarkko Jokihaara; Ilkka Pörsti; Ilari Pajamäki; Tuomo Vuohelainen; Pasi Jolma; Peeter Kööbi; Jarkko Kalliovalkama; Onni Niemelä; Pekka Kannus; Harri Sievänen; Teppo L N Järvinen
Paricalcitol [19-nor-1,25-(OH)2D2] in the treatment of experimental renal bone disease.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006;21(5):745-51.
2006: Heidi Koivisto; Johanna Hietala; Petra Anttila; Seppo Parkkila; Onni Niemelä
Long-term ethanol consumption and macrocytosis: diagnostic and pathogenic implications.
The Journal of laboratory and clinical medicine 2006;147(4):191-6.
2005: Johanna Hietala; Katri Puukka; Heidi Koivisto; Petra Anttila; Onni Niemelä
Serum gamma-glutamyl transferase in alcoholics, moderate drinkers and abstainers: effect on gt reference intervals at population level.
Alcohol and alcoholism (Oxford, Oxfordshire) 2005;40(6):511-4.
2005: Thomas L Freeman; Dean J Tuma; Geoffrey M Thiele; Lynell W Klassen; Simon Worrall; Onni Niemelä; Seppo Parkkila; Peter W Emery; Victor R Preedy
Recent advances in alcohol-induced adduct formation.
Alcoholism, clinical and experimental research 2005;29(7):1310-6.
2005: Olli Savola; Onni Niemelä; Matti Hillbom
Alcohol intake and the pattern of trauma in young adults and working aged people admitted after trauma.
Alcohol and alcoholism (Oxford, Oxfordshire) 2005;40(4):269-73.
2005: Jaana Latvala; Johanna Hietala; Heidi Koivisto; Kimmo Järvi; Petra Anttila; Onni Niemelä
Immune Responses to Ethanol Metabolites and Cytokine Profiles Differentiate Alcoholics with or without Liver Disease.
The American journal of gastroenterology 2005;100(6):1303-10.
2005: Petra Anttila; Kimmo Järvi; Jaana Latvala; Jarkko Romppanen; Kari Punnonen; Onni Niemelä
Biomarkers of alcohol consumption in patients classified according to the degree of liver disease severity.
Scandinavian journal of clinical and laboratory investigation 2005;65(2):141-51.
2004: Alejandra Rodriguez Martinez; Onni Niemelä; Seppo Parkkila
Hepatic and extrahepatic expression of the new iron regulatory protein hemojuvelin.
Haematologica 2004;89(12):1441-5.
2004: Olli Savola; Onni Niemelä; Matti Hillbom
Blood alcohol is the best indicator of hazardous alcohol drinking in young adults and working-age patients with trauma.
Alcohol and alcoholism (Oxford, Oxfordshire) 2004;39(4):340-5.
2004: Olli Savola; Juhani Pyhtinen; Tuomo K Leino; Simo Siitonen; Onni Niemelä; Matti Hillbom
Effects of head and extracranial injuries on serum protein S100B levels in trauma patients.
The Journal of trauma 2004;56(6):1229-34; discussion 1234.
2004: Jaana Latvala; Seppo Parkkila; Onni Niemelä
Excess alcohol consumption is common in patients with cytopenia: studies in blood and bone marrow cells.
Alcoholism, clinical and experimental research 2004;28(4):619-24.
2004: Onni Niemelä; Seppo Parkkila
Alcoholic macrocytosis--is there a role for acetaldehyde and adducts?
Addiction biology 2004;9(1):3-10.
2004: Petra Anttila; Kimmo Järvi; Jaana Latvala; Onni Niemelä
Method-dependent characteristics of carbohydrate-deficient transferrin measurements in the follow-up of alcoholics.
Alcohol and alcoholism (Oxford, Oxfordshire) 2004;39(1):59-63.
2003: Onni Niemelä; Seppo Parkkila; Simon Worrall; Peter W Emery; Victor R Preedy
Generation of aldehyde-derived protein modifications in ethanol-exposed heart.
Alcoholism, clinical and experimental research 2003;27(12):1987-92.
2003: Petra Anttila; Kimmo Järvi; Jaana Latvala; Joan E Blake; Onni Niemelä
A new modified gamma-%CDT method improves the detection of problem drinking: studies in alcoholics with or without liver disease.
Clinica chimica acta; international journal of clinical chemistry 2003;338(1-2):45-51.
2003: Junko Adachi; Migiwa Asano; Yasuhiro Ueno; Onni Niemelä; Kay Ohlendieck; Timothy J Peters; Victor R Preedy
Alcoholic muscle disease and biomembrane perturbations (review).
The Journal of nutritional biochemistry 2003;14(11):616-25.
2003: Petra Anttila; Kimmo Järvi; Jaana Latvala; Joan E Blake; Onni Niemelä
Diagnostic characteristics of different carbohydrate-deficient transferrin methods in the detection of problem drinking: effects of liver disease and alcohol consumption.
Alcohol and alcoholism (Oxford, Oxfordshire) 2003;38(5):415-20.
2003: Martti J Larikka; Aapo Ahonen; Onni Niemelä; Juhani A Junila; Martti M Hämäläinen; Hannu Syrjälä
Specificity of 99mTc-ciprofloxacin imaging.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2003;44(8):1368; author reply 1368.
2003: Jokke Hannuksela; Onni Niemelä; Mari Leppilampi; Anna-Kaisa Parkkila; Pirjo Koistinen; Pentti Nieminen; Seppo Parkkila
Clinical utility and outcome of HFE-genotyping in the search for hereditary hemochromatosis.
Clinica chimica acta; international journal of clinical chemistry 2003;331(1-2):61-7.
2002: Onni Niemelä; Seppo Parkkila; Michael Koll; Victor R Preedy
Generation of protein adducts with malondialdehyde and acetaldehyde in muscles with predominantly type I or type II fibers in rats exposed to ethanol and the acetaldehyde dehydrogenase inhibitor cyanamide.
The American journal of clinical nutrition 2002;76(3):668-74.
2002: Jarkko Romppanen; Kari Punnonen; Petra Anttila; Tuula Jakobsson; Joan Blake; Onni Niemelä
Serum sialic acid as a marker of alcohol consumption: effect of liver disease and heavy drinking.
Alcoholism, clinical and experimental research 2002;26(8):1234-8.
2002: Onni Niemelä; Seppo Parkkila; Blair Bradford; Yuji Iimuro; Markku Pasanen; Ronald G Thurman
Effect of Kupffer cell inactivation on ethanol-induced protein adducts in the liver.
Free radical biology & medicine 2002;33(3):350-5.
2002: Charles H Halsted; Jesus A Villanueva; Angela M Devlin; Onni Niemelä; Seppo Parkkila; Timothy A Garrow; Lynn M Wallock; Mark K Shigenaga; Stepan Melnyk; S Jill James
Folate deficiency disturbs hepatic methionine metabolism and promotes liver injury in the ethanol-fed micropig.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(15):10072-7.
2002: Mari Leppilampi; Pirjo Koistinen; Eeva-Riitta Savolainen; Jokke Hannuksela; Anna-Kaisa Parkkila; Onni Niemelä; Silvia Pastoreková; Jaromir Pastorek; Abdul Waheed; William S Sly; Seppo Parkkila; Hannu J Rajaniemi
The expression of carbonic anhydrase II in hematological malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(7):2240-5.
2002: Martti J Larikka; Aapo Ahonen; Onni Niemelä; Juhani A Junila; Martti M Hämäläinen; K Britton; Hannu Syrjälä
Comparison of 99mTc ciprofloxacin, 99mTc white blood cell and three-phase bone imaging in the diagnosis of hip prosthesis infections: improved diagnostic accuracy with extended imaging time.
Nuclear medicine communications 2002;23(7):655-61.
2002: Martti J Larikka; Aapo Ahonen; Onni Niemelä; O Puronto; Juhani A Junila; Martti M Hämäläinen; K Britton; Hannu Syrjälä
99m Tc-ciprofloxacin (Infecton) imaging in the diagnosis of knee prosthesis infections.
Nuclear medicine communications 2002;23(2):167-70.
2001: Onni Niemelä
Distribution of ethanol-induced protein adducts in vivo: relationship to tissue injury.
Free radical biology & medicine 2001;31(12):1533-8.
2001: Seppo Parkkila; Onni Niemelä; Robert S Britton; Robert E Fleming; A Waheed; Bruce R Bacon; William S Sly
Molecular aspects of iron absorption and HFE expression.
Gastroenterology 2001;121(6):1489-96.
2001: Jaana Latvala; J Melkko; Seppo Parkkila; Kimmo Järvi; K Makkonen; Onni Niemelä
Assays for acetaldehyde-derived adducts in blood proteins based on antibodies against acetaldehyde/lipoprotein condensates.
Alcoholism, clinical and experimental research 2001;25(11):1648-53.
2001: Martti J Larikka; Aapo Ahonen; Juhani A Junila; Onni Niemelä; Martti M Hämäläinen; Hannu Syrjälä
Improved method for detecting knee replacement infections based on extended combined 99mTc-white blood cell/bone imaging.
Nuclear medicine communications 2001;22(10):1145-50.
2001: Jaana Latvala; Seppo Parkkila; J Melkko; Onni Niemelä
Acetaldehyde adducts in blood and bone marrow of patients with ethanol-induced erythrocyte abnormalities.
Molecular medicine (Cambridge, Mass.) 2001;7(6):401-5.
2001: Seppo Parkkila; Onni Niemelä; Eeva-Riitta Savolainen; Pirjo Koistinen
HFE mutations do not account for transfusional iron overload in patients with acute myeloid leukemia.
Transfusion 2001;41(6):828-31.
2001: Martti J Larikka; Aapo Ahonen; Juhani A Junila; Onni Niemelä; Martti M Hämäläinen; Hannu Syrjälä
Extended combined 99mTc-white blood cell and bone imaging improves the diagnostic accuracy in the detection of hip replacement infections.
European journal of nuclear medicine 2001;28(3):288-93.
2001: K Makkonen; Katja Viitala; Seppo Parkkila; Onni Niemelä
Serum IgG and IgE antibodies against mold-derived antigens in patients with symptoms of hypersensitivity.
Clinica chimica acta; international journal of clinical chemistry 2001;305(1-2):89-98.
2000: Onni Niemelä; Seppo Parkkila; Risto O Juvonen; Katja Viitala; H V Gelboin; Markku Pasanen
Cytochromes P450 2A6, 2E1, and 3A and production of protein-aldehyde adducts in the liver of patients with alcoholic and non-alcoholic liver diseases.
Journal of hepatology 2000;33(6):893-901.
2000: Jyrki Rintala; Pia Jaatinen; Seppo Parkkila; Maija Sarviharju; Kalervo Kiianmaa; Antti Hervonen; Onni Niemelä
Evidence of acetaldehyde-protein adduct formation in rat brain after lifelong consumption of ethanol.
Alcohol and alcoholism (Oxford, Oxfordshire) 2000;35(5):458-63.
2000: Katja Viitala; K Makkonen; Y Israel; T Lehtimäki; Olli Jaakkola; Timo Koivula; Joan E Blake; Onni Niemelä
Autoimmune responses against oxidant stress and acetaldehyde-derived epitopes in human alcohol consumers.
Alcoholism, clinical and experimental research 2000;24(7):1103-9.
1999: Seppo Parkkila; Charles H Halsted; Jesus A Villanueva; H Kalervo Väänänen; Onni Niemelä
Expression of testosterone-dependent enzyme, carbonic anhydrase III, and oxidative stress in experimental alcoholic liver disease.
Digestive diseases and sciences 1999;44(11):2205-13.
1999: Onni Niemelä; Seppo Parkkila; Markku Pasanen; Katja Viitala; Jesus A Villanueva; Charles H Halsted
Induction of cytochrome P450 enzymes and generation of protein-aldehyde adducts are associated with sex-dependent sensitivity to alcohol-induced liver disease in micropigs.
Hepatology (Baltimore, Md.) 1999;30(4):1011-7.
1999: Onni Niemelä; Seppo Parkkila; Robert S Britton; E Brunt; Christine G Janney; Bruce R Bacon
Hepatic lipid peroxidation in hereditary hemochromatosis and alcoholic liver injury.
The Journal of laboratory and clinical medicine 1999;133(5):451-60.
1999: TP Laine; Aapo Ahonen; Pentti Torniainen; J Heikkilä; Juhani Pyhtinen; Pirkko Räsänen; Onni Niemelä; Matti Hillbom
Dopamine transporters increase in human brain after alcohol withdrawal.
Molecular psychiatry 1999;4(2):189-91, 104-5.
1998: Onni Niemelä; Seppo Parkkila; Markku Pasanen; Yuji Iimuro; B Bradford; R G Thurman
Early alcoholic liver injury: formation of protein adducts with acetaldehyde and lipid peroxidation products, and expression of CYP2E1 and CYP3A.
Alcoholism, clinical and experimental research 1998;22(9):2118-24.
1998: Katja Viitala; K Lähdesmäki; Onni Niemelä
Comparison of the Axis %CDT TIA and the CDTect method as laboratory tests of alcohol abuse.
Clinical chemistry 1998;44(6 Pt 1):1209-15.
1997: Katja Viitala; Y Israel; Joan E Blake; Onni Niemelä
Serum IgA, IgG, and IgM antibodies directed against acetaldehyde-derived epitopes: relationship to liver disease severity and alcohol consumption.
Hepatology (Baltimore, Md.) 1997;25(6):1418-24.
1997: Anna-Kaisa Parkkila; Seppo Parkkila; M Reunanen; Onni Niemelä; Seppo Tuisku; I Rautakorpi; Hannu J Rajaniemi
Carbonic anhydrase II in the cerebrospinal fluid: its value as a disease marker.
European journal of clinical investigation 1997;27(5):392-7.
1996: Katja Viitala; J E Blake; Yedy Israel; Onni Niemelä
Sensitivity and specificity of carbohydrate-deficient transferrin as a marker of alcohol abuse are significantly influenced by alterations in serum transferrin: comparison of two methods.
Alcoholism, clinical and experimental research 1996;20(3):449-54.
1996: S Parkkila; Onni Niemelä; Robert S Britton; K E Brown; S Ylä-Herttuala; Rosemary O'Neill; Bruce R Bacon
Vitamin E decreases hepatic levels of aldehyde-derived peroxidation products in rats with iron overload.
The American journal of physiology 1996;270(2 Pt 1):G376-84.
1995: Onni Niemelä; Katja Viitala; J E Blake; Yedy Israel
Carbohydrate-deficient transferrin as a marker of alcohol abuse: relationship to alcohol consumption, severity of liver disease, and fibrogenesis.
Alcoholism, clinical and experimental research 1995;19(5):1203-8.
1995: Onni Niemelä; S Parkkila; S Ylä-Herttuala; J Villanueva; Boris Henry Ruebner; Charles H Halsted
Sequential acetaldehyde production, lipid peroxidation, and fibrogenesis in micropig model of alcohol-induced liver disease.
Hepatology (Baltimore, Md.) 1995;22(4 Pt 1):1208-14.
1995: H Tsukamoto; W Horne; S Kamimura; Onni Niemelä; S Parkkila; S Ylä-Herttuala; Gary Brittenham
Experimental liver cirrhosis induced by alcohol and iron.
The Journal of clinical investigation 1995;96(1):620-30.
1995: S Parkkila; Onni Niemelä
[Current aspects of alcohol-induced liver damage].
Duodecim; lääketieteellinen aikakauskirja 1995;111(13):1194-201.
1994: Tatu Juvonen; S Parkkila; Anna-Kaisa Parkkila; Onni Niemelä; L H Lajunen; MI Kairaluoma; P Perämäki; Hannu J Rajaniemi
High-activity carbonic anhydrase isoenzyme (CA II) in human gallbladder epithelium.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1994;42(10):1393-7.
1994: Onni Niemelä; S Parkkila; S Ylä-Herttuala; C Halsted; J L Witztum; A Lanca; Y Israel
Covalent protein adducts in the liver as a result of ethanol metabolism and lipid peroxidation.
Laboratory investigation; a journal of technical methods and pathology 1994;70(4):537-46.
1994: Onni Niemelä
Collagen breakdown products as markers of fibrosis and cirrhosis.
Alcohol and alcoholism (Oxford, Oxfordshire). Supplement 1994;2():345-52.
1994: Tatu Juvonen; Onni Niemelä; A Reinilä; J Nissinen; MI Kairaluoma
Spontaneous intraabdominal haemorrhage caused by segmental mediolytic arteritis in a patient with systemic lupus erythematosus--an underestimated entity of autoimmune origin?
European journal of vascular surgery 1994;8(1):96-100.
1994: Tatu Juvonen; O Räsänen; A Reinilä; S Parkkila; J Nissinen; MI Kairaluoma; Raija Sormunen; Onni Niemelä
Segmental mediolytic arteritis--electronmicroscopic and immunohistochemical study.
European journal of vascular surgery 1994;8(1):70-7.
1994: Tatu Juvonen; S Parkkila; M Lepojärvi; Onni Niemelä
Demonstration of a bioactive elastin-derived peptide (Val-Gly-Val-Ala-Pro-Gly) in vascular lesions characterised by the segmental destruction of media.
Annales chirurgiae et gynaecologiae 1994;83(4):296-302.
1993: Charles H Halsted; J Villanueva; C J Chandler; Boris Henry Ruebner; R J Munn; S Parkkila; Onni Niemelä
Centrilobular distribution of acetaldehyde and collagen in the ethanol-fed micropig.
Hepatology (Baltimore, Md.) 1993;18(4):954-60.
1993: H Rönty; A Ahonen; Uolevi Tolonen; J Heikkilä; Onni Niemelä
Cerebral trauma and alcohol abuse.
European journal of clinical investigation 1993;23(3):182-7.
1993: Onni Niemelä
Acetaldehyde adducts of proteins: diagnostic and pathogenic implications in diseases caused by excessive alcohol consumption.
Scandinavian journal of clinical and laboratory investigation. Supplementum 1993;213():45-54.
1993: Tatu Juvonen; MI Kairaluoma; H Malinen; Onni Niemelä
Extracellular matrix proteins in bile and serum of patients with gallstone disease.
Connective tissue research 1993;29(3):171-80.
1992: Onni Niemelä; J E Blake; H Orrego
Serum type I collagen propeptide and severity of alcoholic liver disease.
Alcoholism, clinical and experimental research 1992;16(6):1064-7.
1992: Yedy Israel; A MacDonald; Onni Niemelä; D Zamel; E Shami; M Zywulko; F Klajner; C Borgono
Hypersensitivity to acetaldehyde-protein adducts.
Molecular pharmacology 1992;42(4):711-7.
1992: Onni Niemelä; Y Israel
Hemoglobin-acetaldehyde adducts in human alcohol abusers.
Laboratory investigation; a journal of technical methods and pathology 1992;67(2):246-52.
1991: Onni Niemelä; E Halmesmäki; Olavi Ylikorkala
Hemoglobin-acetaldehyde adducts are elevated in women carrying alcohol-damaged fetuses.
Alcoholism, clinical and experimental research 1991;15(6):1007-10.
1991: Onni Niemelä; T Juvonen; S Parkkila
Immunohistochemical demonstration of acetaldehyde-modified epitopes in human liver after alcohol consumption.
The Journal of clinical investigation 1991;87(4):1367-74.
1991: Onni Niemelä; Juha Risteli; J E Blake; L Risteli; K V Compton; H Orrego
Connective tissue metabolism and alcohol intake in alcoholic liver disease.
Alcohol and alcoholism (Oxford, Oxfordshire). Supplement 1991;1():351-5.
1990: Onni Niemelä; Y Israel; Y Mizoi; T Fukunaga; C J Eriksson
Hemoglobin-acetaldehyde adducts in human volunteers following acute ethanol ingestion.
Alcoholism, clinical and experimental research 1990;14(6):838-41.
1990: Onni Niemelä; Juha Risteli; J E Blake; L Risteli; K V Compton; H Orrego
Markers of fibrogenesis and basement membrane formation in alcoholic liver disease. Relation to severity, presence of hepatitis, and alcohol intake.
Gastroenterology 1990;98(6):1612-9.
1990: Onni Niemelä; R M Mannermaa; Jorma Oikarinen
Impairment of histone H1 DNA binding by adduct formation with acetaldehyde.
Life sciences 1990;47(24):2241-9.
1989: Arja Jukkola; Onni Niemelä
Covalent binding of acetaldehyde to type III collagen.
Biochemical and biophysical research communications 1989;159(1):163-9.
1988: Onni Niemelä; L Risteli; E A Sotaniemi; Frej Stenbäck; Juha Risteli
Serum basement membrane and type III procollagen-related antigens in primary biliary cirrhosis.
Journal of hepatology 1988;6(3):307-14.
1988: Yedy Israel; A MacDonald; T Waks; Onni Niemelä
Induction of an allergic reaction to alcohol metabolites by immunization.
Archivos de biología y medicina experimentales 1988;21(1):71-3.
1988: Yedy Israel; H Orrego; Onni Niemelä
Immune responses to alcohol metabolites: pathogenic and diagnostic implications.
Seminars in liver disease 1988;8(1):81-90.
1987: Onni Niemelä; F Klajner; H Orrego; E Vidins; Laurie Blendis; Yedy Israel
Antibodies against acetaldehyde-modified protein epitopes in human alcoholics.
Hepatology (Baltimore, Md.) 1987;7(6):1210-4.
1987: Y Israel; Onni Niemelä; J Khanna; H Orrego
Antibodies against acetaldehyde- modified epitopes: a new perspective.
Progress in clinical and biological research 1987;241():283-9.
1986: Arja Jukkola; Juha Risteli; Onni Niemelä; L Risteli
Incorporation of sulphate into type III procollagen by cultured human fibroblasts. Identification of tyrosine O-sulphate.
European journal of biochemistry / FEBS 1986;154(1):219-24.