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Frans Nijkamp

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Marco Thio; Bart R Blokhuis; Marcel J Fischer; Tom Groot Kormelink; Frans P Nijkamp; Frank A Redegeld
Antigen binding characteristics of immunoglobulin free light chains: crosslinking by antigen is essential to induce allergic inflammation.
Sven van Eijl; Ana F Ferreira; Gert Folkerts; Frieke Kuper; Esmaeil Mortaz; Frans P Nijkamp; Nanne Bloksma
Humic acid enhances cigarette smoke-induced lung emphysema in mice and IL-8 release of human monocytes.
Saskia A Overbeek; Martine J Smit; Anja I Srienc; Guido J R Zaman; Johan Garssen; P A J Henricks; Pim J Koelink; Aletta D Kraneveld; Herman D Lim; Frans P Nijkamp; Petra de Kruijf; Gert Folkerts
N-acetylated Proline-Glycine-Proline induced G-protein dependent chemotaxis of neutrophils is independent of CXCL8 release.

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2012: Marco Thio; Bart R Blokhuis; Marcel J Fischer; Tom Groot Kormelink; Frans P Nijkamp; Frank A Redegeld
Antigen binding characteristics of immunoglobulin free light chains: crosslinking by antigen is essential to induce allergic inflammation.
PloS one 2012;7(7):e40986.
2011: Sven van Eijl; Ana F Ferreira; Gert Folkerts; Frieke Kuper; Esmaeil Mortaz; Frans P Nijkamp; Nanne Bloksma
Humic acid enhances cigarette smoke-induced lung emphysema in mice and IL-8 release of human monocytes.
Pulmonary pharmacology & therapeutics 2011;24(6):682-9.
2011: Saskia A Overbeek; Martine J Smit; Anja I Srienc; Guido J R Zaman; Johan Garssen; P A J Henricks; Pim J Koelink; Aletta D Kraneveld; Herman D Lim; Frans P Nijkamp; Petra de Kruijf; Gert Folkerts
N-acetylated Proline-Glycine-Proline induced G-protein dependent chemotaxis of neutrophils is independent of CXCL8 release.
European journal of pharmacology 2011;668(3):428-34.
2011: Joris Kloek; Esmaeil Mortaz; Ingrid van Ark; Nanne Bloksma; Johan Garssen; Frans P Nijkamp; Gert Folkerts
A whey-based glutathione-enhancing diet decreases allergen-induced airway contraction in a guinea-pig model of asthma.
The British journal of nutrition 2011;105(10):1465-70.
2011: S van Eijl; C Versluis; Gert Folkerts; Esmaeil Mortaz; Frans P Nijkamp; Nanne Bloksma
A low vitamin A status increases the susceptibility to cigarette smoke-induced lung emphysema in C57BL/6J mice.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2011;62(2):175-82.
2011: Saskia Braber; Pim J Koelink; P A J Henricks; Patricia L Jackson; Frans P Nijkamp; Johan Garssen; Aletta D Kraneveld; J Edwin Blalock; Gert Folkerts
Cigarette smoke-induced lung emphysema in mice is associated with prolyl endopeptidase, an enzyme involved in collagen breakdown.
American journal of physiology. Lung cellular and molecular physiology 2011;300(2):L255-65.
2010: Esmaeil Mortaz; I M Adcock; K Ito; Aletta D Kraneveld; Frans P Nijkamp; Gert Folkerts
Cigarette smoke induces CXCL8 production by human neutrophils via activation of TLR9 receptor.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2010;36(5):1143-54.
2010: Esmaeil Mortaz; Gert Folkerts; Frans P Nijkamp; P A J Henricks
ATP and the pathogenesis of COPD.
European journal of pharmacology 2010;638(1-3):1-4.
2010: Anneke Rijnierse; Frank A Redegeld; Bart R Blokhuis; Maurice W van der Heijden; Anje A Te Velde; Inge Pronk; Daniel W Hommes; Frans P Nijkamp; Andries Koster; Aletta D Kraneveld
Ig-free light chains play a crucial role in murine mast cell-dependent colitis and are associated with human inflammatory bowel diseases.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(1):653-9.
2010: Betty C A M van Esch; Bastiaan Schouten; Gerard A Hofman; Ton van Baalen; Frans P Nijkamp; Léon M J Knippels; Linette E M Willemsen; Johan Garssen
Acute allergic skin response as a new tool to evaluate the allergenicity of whey hydrolysates in a mouse model of orally induced cow's milk allergy.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2010;21(4 Pt 2):e780-6.
2010: Hadi Sarir; Esmaeil Mortaz; Willem T Janse; Masoumeh E Givi; Frans P Nijkamp; Gert Folkerts
IL-8 production by macrophages is synergistically enhanced when cigarette smoke is combined with TNF-alpha.
Biochemical pharmacology 2010;79(5):698-705.
2010: Saskia Braber; P A J Henricks; Frans P Nijkamp; Aletta D Kraneveld; Gert Folkerts
Inflammatory changes in the airways of mice caused by cigarette smoke exposure are only partially reversed after smoking cessation.
Respiratory research 2010;11():99.
2009: Esmaeil Mortaz; Saskia Braber; Maiwand Nazary; Masoumh Ezzati Givi; Frans P Nijkamp; Gert Folkerts
ATP in the pathogenesis of lung emphysema.
European journal of pharmacology 2009;619(1-3):92-6.
2009: Esmaeil Mortaz; Ferdi Engels; Frans P Nijkamp; Frank A Redegeld
New insights on the possible role of mast cells in aspirin-induced asthma.
Current molecular pharmacology 2009;2(2):182-9.
2009: Esmaeil Mortaz; Gert Folkerts; Ferdi Engels; Frans P Nijkamp; Frank A Redegeld
Cigarette smoke suppresses in vitro allergic activation of mouse mast cells.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2009;39(5):679-87.
2009: Anneke Rijnierse; alfons kroese; Frank A Redegeld; Bart R J Blokhuis; Maurice W van der Heijden; Andries Koster; Jean-Pierre Timmermans; Frans P Nijkamp; Aletta D Kraneveld
Immunoglobulin-free light chains mediate antigen-specific responses of murine dorsal root ganglion neurons.
Journal of neuroimmunology 2009;208(1-2):80-6.
2009: Esmaeil Mortaz; Zsofia Lazar; Leo Koenderman; Aletta D Kraneveld; Frans P Nijkamp; Gert Folkerts
Cigarette smoke attenuates the production of cytokines by human plasmacytoid dendritic cells and enhances the release of IL-8 in response to TLR-9 stimulation.
Respiratory research 2009;10():47.
2009: Hadi Sarir; Esmaeil Mortaz; Khalil Karimi; Aletta D Kraneveld; Irfan Rahman; Eric Caldenhoven; Frans P Nijkamp; Gert Folkerts
Cigarette smoke regulates the expression of TLR4 and IL-8 production by human macrophages.
Journal of inflammation (London, England) 2009;6():12.
2009: Esmaeil Mortaz; Aletta D Kraneveld; Joost J Smit; Mirjam Kool; Bart N Lambrecht; Steven Kunkel; Nicholas W Lukacs; Frans P Nijkamp; Gert Folkerts
Effect of cigarette smoke extract on dendritic cells and their impact on T-cell proliferation.
PloS one 2009;4(3):e4946.
2009: T Groot Kormelink; M Thio; B R Blokhuis; Frans P Nijkamp; Frank A Redegeld
Atopic and non-atopic allergic disorders: current insights into the possible involvement of free immunoglobulin light chains.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2009;39(1):33-42.
2008: Esmaeil Mortaz; Mehdi Vaezi Rad; Malcolm Johnson; Danielle Raats; Frans P Nijkamp; Gert Folkerts
Salmeterol with fluticasone enhances the suppression of IL-8 release and increases the translocation of glucocorticoid receptor by human neutrophils stimulated with cigarette smoke.
Journal of molecular medicine (Berlin, Germany) 2008;86(9):1045-56.
2008: Anneke H van Houwelingen; Nathaniel M Weathington; Vivienne Verweij; J Edwin Blalock; Frans P Nijkamp; Gert Folkerts
Induction of lung emphysema is prevented by L-arginine-threonine-arginine.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(9):3403-8.
2008: Aletta D Kraneveld; Anneke Rijnierse; Frans P Nijkamp; Johan Garssen
Neuro-immune interactions in inflammatory bowel disease and irritable bowel syndrome: future therapeutic targets.
European journal of pharmacology 2008;585(2-3):361-74.
2008: Alma J Nauta; Ferdi Engels; Leon M Knippels; Johan Garssen; Frans P Nijkamp; Frank A Redegeld
Mechanisms of allergy and asthma.
European journal of pharmacology 2008;585(2-3):354-60.
2008: Hadi Sarir; P A J Henricks; Anneke H van Houwelingen; Frans P Nijkamp; Gert Folkerts
Cells, mediators and Toll-like receptors in COPD.
European journal of pharmacology 2008;585(2-3):346-53.
2008: Gert Folkerts; Aletta D Kraneveld; Frans P Nijkamp
New endogenous CXC chemokine ligands as potential targets in lung emphysema.
Trends in pharmacological sciences 2008;29(4):181-5.
2008: Marco Thio; Bart R Blokhuis; Frans P Nijkamp; Frank A Redegeld
Free immunoglobulin light chains: a novel target in the therapy of inflammatory diseases.
Trends in pharmacological sciences 2008;29(4):170-4.
2008: Esmaeil Mortaz; Frank A Redegeld; Hadi Sarir; Khalil Karimi; Danielle Raats; Frans P Nijkamp; Gert Folkerts
Cigarette smoke stimulates the production of chemokines in mast cells.
Journal of leukocyte biology 2008;83(3):575-80.
2008: T J Steenhuis; W M C van Aalderen; Nanne Bloksma; Frans P Nijkamp; Johan van der Laag; Henk Van Loveren; Ger T Rijkers; W Kuis; Maarten O Hoekstra
Bacille-Calmette-Guerin vaccination and the development of allergic disease in children: a randomized, prospective, single-blind study.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2008;38(1):79-85.
2007: Anneke Rijnierse; Frans P Nijkamp; Aletta D Kraneveld
Mast cells and nerves tickle in the tummy: implications for inflammatory bowel disease and irritable bowel syndrome.
Pharmacology & therapeutics 2007;116(2):207-35.
2007: Hadi Sarir; Esmaeil Mortaz; Khalil Karimi; Malcolm Johnson; Frans P Nijkamp; Gert Folkerts
Combination of fluticasone propionate and salmeterol potentiates the suppression of cigarette smoke-induced IL-8 production by macrophages.
European journal of pharmacology 2007;571(1):55-61.
2007: Esmaeil Mortaz; Frank A Redegeld; Katherine E Dunsmore; Kelli Odoms; Hector R Wong; Frans P Nijkamp; Ferdi Engels
Stimulation of cysteinyl leukotriene production in mast cells by heat shock and acetylsalicylic acid.
European journal of pharmacology 2007;561(1-3):214-9.
2007: Anneke H van Houwelingen; K Kaczynska; Aletta D Kraneveld; Mirjam Kool; Frans P Nijkamp; Frank A Redegeld
Topical application of F991, an immunoglobulin free light chain antagonist, prevents development of contact sensitivity in mice.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2007;37(2):270-5.
2007: Francesco Blasi; Stefano Aliberti; Luigi Allegra; Gioia Piatti; Paolo Tarsia; Jacobus M Ossewaarde; Vivienne Verweij; Frans P Nijkamp; Gert Folkerts
Chlamydophila pneumoniae induces a sustained airway hyperresponsiveness and inflammation in mice.
Respiratory research 2007;8():83.
2006: Anneke Rijnierse; Andries Koster; Frans P Nijkamp; Aletta D Kraneveld
TNF-alpha is crucial for the development of mast cell-dependent colitis in mice.
American journal of physiology. Gastrointestinal and liver physiology 2006;291(5):G969-76.
2006: Anneke Rijnierse; Kim M F van Zijl; Andries Koster; Frans P Nijkamp; Aletta D Kraneveld
Beneficial effect of tachykinin NK1 receptor antagonism in the development of hapten-induced colitis in mice.
European journal of pharmacology 2006;548(1-3):150-7.
2006: S van Eijl; Ruud van Oorschot; Berend Olivier; Frans P Nijkamp; Nanne Bloksma
Stress and hypothermia in mice in a nose-only cigarette smoke exposure system.
Inhalation toxicology 2006;18(11):911-8.
2006: Annick de Vries; Ferdi Engels; P A J Henricks; Thea Leusink-Muis; G P McGregor; Armin Braun; D A Groneberg; M C Dessing; Frans P Nijkamp; A Fischer
Airway hyper-responsiveness in allergic asthma in guinea-pigs is mediated by nerve growth factor via the induction of substance P: a potential role for trkA.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2006;36(9):1192-200.
2006: Dingena L Valstar; Marcel A Schijf; Josje H E Arts; frieke kuper; Frans P Nijkamp; Gert Storm; Nanne Bloksma; P A J Henricks
Alveolar macrophages suppress non-specific inflammation caused by inhalation challenge with trimellitic anhydride conjugated to albumin.
Archives of toxicology 2006;80(9):561-71.
2006: Esmaeil Mortaz; Frank A Redegeld; Frans P Nijkamp; Ferdi Engels
Aspirin induces the production of the inflammatory mediator 8-epi-PGF in mast cells.
European journal of pharmacology 2006;543(1-3):190-3.
2006: Fabio L M Ricciardolo; Frans P Nijkamp; Gert Folkerts
Nitric oxide synthase (NOS) as therapeutic target for asthma and chronic obstructive pulmonary disease.
Current drug targets 2006;7(6):721-35.
2006: Esmaeil Mortaz; Frank A Redegeld; Nanne Bloksma; Katherine E Dunsmore; Alvin Denenberg; Hector R Wong; Frans P Nijkamp; Ferdi Engels
Induction of HSP70 is dispensable for anti-inflammatory action of heat shock or NSAIDs in mast cells.
Experimental hematology 2006;34(4):414-23.
2006: Anneke Rijnierse; Andries Koster; Frans P Nijkamp; Aletta D Kraneveld
Critical role for mast cells in the pathogenesis of 2,4-dinitrobenzene-induced murine colonic hypersensitivity reaction.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(7):4375-84.
2006: Nathaniel M Weathington; Anneke H van Houwelingen; Brett D Noerager; Patricia L Jackson; Aletta D Kraneveld; F Shawn Galin; Gert Folkerts; Frans P Nijkamp; J Edwin Blalock
A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation.
Nature medicine 2006;12(3):317-23.
2006: Judy J Watson; Mark S Fahey; Edwin van den Worm; Ferdi Engels; Frans P Nijkamp; Paul Stroemer; Steve McMahon; Shelley J Allen; David Dawbarn
TrkAd5: A novel therapeutic agent for treatment of inflammatory pain and asthma.
The Journal of pharmacology and experimental therapeutics 2006;316(3):1122-9.
2006: Dingena L Valstar; Marcel A Schijf; Frans P Nijkamp; Gert Storm; Josje H E Arts; frieke kuper; Nanne Bloksma; P A J Henricks
Alveolar macrophages have a dual role in a rat model for trimellitic anhydride-induced occupational asthma.
Toxicology and applied pharmacology 2006;211(1):20-9.
2006: Gert Folkerts; Frans P Nijkamp
Nitric oxide in asthma therapy.
Current pharmaceutical design 2006;12(25):3221-32.
2006: Dingena L Valstar; Marcel A Schijf; Erietta Stelekati; Frans P Nijkamp; Nanne Bloksma; P A J Henricks
Trimellitic anhydride-conjugated serum albumin activates rat alveolar macrophages in vitro.
Journal of occupational medicine and toxicology (London, England) 2006;1():13.
2006: Khalil Karimi; Hadi Sarir; Esmaeil Mortaz; Joost J Smit; Hossein Hosseini; Sjef De Kimpe; Frans P Nijkamp; Gert Folkerts
Toll-like receptor-4 mediates cigarette smoke-induced cytokine production by human macrophages.
Respiratory research 2006;7():66.
2006: Robert Ten Broeke; Rini de Crom; Rien van Haperen; Vivienne Verweij; Thea Leusink-Muis; Ingrid van Ark; Fred De Clerck; Frans P Nijkamp; Gert Folkerts
Overexpression of endothelial nitric oxide synthase suppresses features of allergic asthma in mice.
Respiratory research 2006;7():58.
2006: Esmaeil Mortaz; Frank A Redegeld; Frans P Nijkamp; Hector R Wong; Ferdi Engels
Acetylsalicylic acid-induced release of HSP70 from mast cells results in cell activation through TLR pathway.
Experimental hematology 2006;34(1):8-18.
2005: Bart P Van Putte; Albert Huisman; Jeroen Hendriks; Paul E Y Van Schil; Wim-Jan van Boven; Franz Schramel; Frans P Nijkamp; Gert Folkerts
Pulmonary intravascular volume can be used for dose calculation in isolated lung perfusion.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2005;28(4):594-8.
2005: Esmaeil Mortaz; Frank A Redegeld; Maurice W van der Heijden; Hector R Wong; Frans P Nijkamp; Ferdi Engels
Mast cell activation is differentially affected by heat shock.
Experimental hematology 2005;33(8):944-52.
2005: Edwin van den Worm; Annick de Vries; Frans P Nijkamp; Ferdi Engels
Capsazepine, a vanilloid receptor antagonist, inhibits allergen-induced tracheal contraction.
European journal of pharmacology 2005;518(1):77-8.
2005: Esmaeil Mortaz; Frank A Redegeld; Frans P Nijkamp; Ferdi Engels
Dual effects of acetylsalicylic acid on mast cell degranulation, expression of cyclooxygenase-2 and release of pro-inflammatory cytokines.
Biochemical pharmacology 2005;69(7):1049-57.
2005: Aletta D Kraneveld; Mirjam Kool; Anneke H van Houwelingen; Paul Roholl; Alan Solomon; Dirkje S Postma; Frans P Nijkamp; Frank A Redegeld
Elicitation of allergic asthma by immunoglobulin free light chains.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(5):1578-83.
2004: Dingena L Valstar; Marcel A Schijf; Frans P Nijkamp; Nanne Bloksma; P A J Henricks
Glutathione-conjugated toluene diisocyanate causes airway inflammation in sensitised mice.
Archives of toxicology 2004;78(9):533-9.
2004: Edwin van den Worm; Frans P Nijkamp; Ferdi Engels
Nerve growth factor and the vanilloid receptor: partners in crime?
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2004;34(7):996-1000.
2004: Joost J Smit; Gert Folkerts; Frans P Nijkamp
Ramp-ing up allergies: Nramp1 (Slc11a1), macrophages and the hygiene hypothesis.
Trends in immunology 2004;25(7):342-7.
2004: Hanneke P M van der Kleij; Aletta D Kraneveld; Anneke H van Houwelingen; Mirjam Kool; Andrys C D Weitenberg; Frank A Redegeld; Frans P Nijkamp
Murine model for non-IgE-mediated asthma.
Inflammation 2004;28(3):115-25.
2004: Gert Folkerts; Frans P Nijkamp
Airway nitrergic pathways: is there therapeutic potential in asthma and COPD?
Current opinion in pharmacology 2004;4(3):202-6.
2004: Khalil Karimi; Mirjam Kool; Frans P Nijkamp; Frank A Redegeld
Substance P can stimulate prostaglandin D2 and leukotriene C4 generation without granule exocytosis in murine mast cells.
European journal of pharmacology 2004;489(1-2):49-54.
2004: Frank A Redegeld; Maurice W van der Heijden; Mirjam Kool; Aletta D Kraneveld; Frans P Nijkamp
Functional role for Ig free light chains in immediate and delayed hypersensitivity responses.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2004;53 Suppl 1():S6-8.
2004: Joost J Smit; Gert Folkerts; Frans P Nijkamp
Mycobacteria, genes and the 'hygiene hypothesis'.
Current opinion in allergy and clinical immunology 2004;4(1):57-62.
2004: Robert Ten Broeke; J Edwin Blalock; Frans P Nijkamp; Gert Folkerts
Calcium sensors as new therapeutic targets for asthma and chronic obstructive pulmonary disease.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2004;34(2):170-6.
2004: Robert Ten Broeke; Thea Leusink-Muis; Rogier Hilberdink; Ingrid van Ark; Edwin van den Worm; Matteo Villain; Fred De Clerck; J Edwin Blalock; Frans P Nijkamp; Gert Folkerts
Specific modulation of calmodulin activity induces a dramatic production of superoxide by alveolar macrophages.
Laboratory investigation; a journal of technical methods and pathology 2004;84(1):29-40.
2003: René Houtman; Jeroen Krijgsveld; Mirjam Kool; Edwin Romijn; Frank A Redegeld; Frans P Nijkamp; albert heck; Ian Humphery-Smith
Lung proteome alterations in a mouse model for nonallergic asthma.
Proteomics 2003;3(10):2008-18.
2003: DT Deurloo; M A T van Berkel; Betty C A M van Esch; Frans M A Hofhuis; Frans P Nijkamp; Mariëtte A Oosterwegel; Antoon J M Van Oosterhout
CD28/CTLA4 double deficient mice demonstrate crucial role for B7 co-stimulation in the induction of allergic lower airways disease.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2003;33(9):1297-304.
2003: Hanneke P M van der Kleij; Aletta D Kraneveld; Frank A Redegeld; Norma P Gerard; Olivier Morteau; Frans P Nijkamp
The tachykinin NK1 receptor is crucial for the development of non-atopic airway inflammation and hyperresponsiveness.
European journal of pharmacology 2003;476(3):249-55.
2003: Robert Ten Broeke; Marcel C Brandhorst; Thea Leusink-Muis; Matteo Villain; Fred De Clerck; J Edwin Blalock; Frans P Nijkamp; Gert Folkerts
Ca2+ sensors modulate asthmatic symptoms in an allergic model for asthma.
European journal of pharmacology 2003;476(1-2):151-7.
2003: Hanneke P M van der Kleij; Donglai Ma; Frank A Redegeld; Aletta D Kraneveld; Frans P Nijkamp; John Bienenstock
Functional expression of neurokinin 1 receptors on mast cells induced by IL-4 and stem cell factor.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(4):2074-9.
2003: Joost J Smit; Henk Van Loveren; Maarten O Hoekstra; Marcel A Schijf; Gert Folkerts; Frans P Nijkamp
Mycobacterium vaccae administration during allergen sensitization or challenge suppresses asthmatic features.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2003;33(8):1083-9.
2003: Joost J Smit; Henk Van Loveren; Maarten O Hoekstra; Khalil Karimi; Gert Folkerts; Frans P Nijkamp
The Slc11a1 (Nramp1) gene controls efficacy of mycobacterial treatment of allergic asthma.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(2):754-60.
2003: Joost J Smit; Henk Van Loveren; Maarten O Hoekstra; Patrick A A Van der Kant; Gert Folkerts; Frans P Nijkamp
Therapeutic treatment with heat-killed Mycobacterium vaccae (SRL172) in a mild and severe mouse model for allergic asthma.
European journal of pharmacology 2003;470(3):193-9.
2003: Joost J Smit; Henk Van Loveren; Maarten O Hoekstra; Frans P Nijkamp; Nanne Bloksma
Influence of the macrophage bacterial resistance gene, Nramp1 (Slc11a1), on the induction of allergic asthma in the mouse.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(8):958-60.
2003: Frank A Redegeld; Frans P Nijkamp
Immunoglobulin free light chains and mast cells: pivotal role in T-cell-mediated immune reactions?
Trends in immunology 2003;24(4):181-5.
2003: Joris Kloek; Ingrid van Ark; Fred De Clerck; Nanne Bloksma; Frans P Nijkamp; Gert Folkerts
Modulation of airway hyperresponsiveness by thiols in a murine in vivo model of allergic asthma.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2003;52(3):126-31.
2002: Joris de Bie; EH Jonker; P A J Henricks; J Hoevenaars; Frédéric F Little; William W Cruikshank; Frans P Nijkamp; Antoon J M Van Oosterhout
Exogenous interleukin-16 inhibits antigen-induced airway hyper-reactivity, eosinophilia and Th2-type cytokine production in mice.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2002;32(11):1651-8.
2002: Muriel Haag; Thea Leusink-Muis; Renaud Le Bouquin; Frans P Nijkamp; Alain Lugnier; Nelly Frossard; Gert Folkerts; Françoise Pons
Increased expression and decreased activity of cytochrome P450 1A1 in a murine model of toluene diisocyanate-induced asthma.
Archives of toxicology 2002;76(11):621-7.
2002: Judith Scheerens; Sandra B E van Gessel; Frans P Nijkamp; Gert Folkerts
Eotaxin protein levels and airway pathology in a mouse model for allergic asthma.
European journal of pharmacology 2002;453(1):111-7.
2002: Vipin Paliwal; Ryohei F Tsuji; Marian Szczepanik; Ivana Kawikova; Regis A Campos; Manfred Kneilling; Martin Röcken; Janine Schuurman; Frank A Redegeld; Frans P Nijkamp; Philip W Askenase
Subunits of IgM reconstitute defective contact sensitivity in B-1 cell-deficient xid mice: kappa light chains recruit T cells independent of complement.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(8):4113-23.
2002: G Sadeghi-Hashjin; Frans P Nijkamp; P A J Henricks; Gert Folkerts
Sodium cromoglycate and doxantrazole are oxygen radical scavengers.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2002;20(4):867-72.
2002: Aletta D Kraneveld; Hanneke P M van der Kleij; Mirjam Kool; Anneke H van Houwelingen; Andrys C D Weitenberg; Frank A Redegeld; Frans P Nijkamp
Key role for mast cells in nonatopic asthma.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(4):2044-53.
2002: edith janssen; Marca H M Wauben; Frans P Nijkamp; Willem van Eden; Antoon J M Van Oosterhout
Immunomodulatory effects of antigen-pulsed macrophages in a murine model of allergic asthma.
American journal of respiratory cell and molecular biology 2002;27(2):257-64.
2002: Joris Kloek; Ingrid van Ark; Nanne Bloksma; Fred De Clerck; Frans P Nijkamp; Gert Folkerts
Glutathione and other low-molecular-weight thiols relax guinea pig trachea ex vivo: interactions with nitric oxide?
American journal of physiology. Lung cellular and molecular physiology 2002;283(2):L403-8.
2002: Anneke H van Houwelingen; Aletta D Kraneveld; Frans P Nijkamp
Hapten-induced hypersensitivity reactions in the airways: atopic versus non-atopic.
Environmental toxicology and pharmacology 2002;11(3-4):197-205.
2002: Frank A Redegeld; Maurice W van der Heijden; Mirjam Kool; Bianca M Heijdra; Johan Garssen; Aletta D Kraneveld; Henk Van Loveren; Paul Roholl; Takashi Saito; Sjef Verbeek; Jill Claassens; Andries Koster; Frans P Nijkamp
Immunoglobulin-free light chains elicit immediate hypersensitivity-like responses.
Nature medicine 2002;8(7):694-701.
2002: Anneke H van Houwelingen; Mirjam Kool; Saskia C A de Jager; Frank A Redegeld; Dicky van Heuven-Nolsen; Aletta D Kraneveld; Frans P Nijkamp
Mast cell-derived TNF-alpha primes sensory nerve endings in a pulmonary hypersensitivity reaction.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(10):5297-302.
2002: Joris Kloek; Frans P Nijkamp; Nanne Bloksma; Fred De Clerck; Gert Folkerts
Differential responsiveness of proximal and distal parts of isolated guinea pig trachea.
European journal of pharmacology 2002;442(3):289-94.
2002: Peter C Groot; B Jerden Van Bergenhenegouwen; Frans P Nijkamp; Antoon J M Van Oosterhout
Identification of novel target proteins in Th2-dominated allergic inflammatory responses using complementary DNA representational difference analysis and complementary DNA microarrays.
Chest 2002;121(3 Suppl):77S-78S.
2002: Antoon J M Van Oosterhout; Prescilla V Jeurink; Peter C Groot; Gerard A Hofman; Frans P Nijkamp; Peter Demant
Genetic analysis of antigen-induced airway manifestations of asthma using recombinant congenic mouse strains.
Chest 2002;121(3 Suppl):13S.
2002: Anneke H van Houwelingen; Saskia C A de Jager; Mirjam Kool; Dicky van Heuven-Nolsen; Aletta D Kraneveld; Frans P Nijkamp
Hypersensitivity reactions in mouse airways after a single and a repeated hapten challenge.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2002;51(2):63-8.
2002: Annick de Vries; Ferdi Engels; P A J Henricks; Thea Leusink-Muis; A Fischer; Frans P Nijkamp
Antibodies directed against nerve growth factor inhibit the acute bronchoconstriction due to allergen challenge in guinea-pigs.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2002;32(2):325-8.
2002: R B R Muijsers; A van der Veeken; J Habernickel; Gert Folkerts; Dirkje S Postma; Frans P Nijkamp
Intra-luminal exposure of murine airways to peroxynitrite causes inflammation but not hyperresponsiveness.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2002;51(1):33-7.
2002: Rob Ruijtenbeek; Cees Versluis; albert heck; Frank A Redegeld; Frans P Nijkamp; Rob M J Liskamp
Characterization of a phosphorylated peptide and peptoid and peptoid-peptide hybrids by mass spectrometry.
Journal of mass spectrometry : JMS 2002;37(1):47-55.
2001: DT Deurloo; Betty C A M van Esch; CL Hofstra; Frans P Nijkamp; Antoon J M Van Oosterhout
CTLA4-IgG reverses asthma manifestations in a mild but not in a more "severe" ongoing murine model.
American journal of respiratory cell and molecular biology 2001;25(6):751-60.
2001: Gert Folkerts; Joris Kloek; R B R Muijsers; Frans P Nijkamp
Reactive nitrogen and oxygen species in airway inflammation.
European journal of pharmacology 2001;429(1-3):251-62.
2001: R B R Muijsers; Nick H T Ten Hacken; Ingrid van Ark; Gert Folkerts; Frans P Nijkamp; Dirkje S Postma
L-Arginine is not the limiting factor for nitric oxide synthesis by human alveolar macrophages in vitro.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2001;18(4):667-71.
2001: Annick de Vries; C van Rijnsoever; Ferdi Engels; P A J Henricks; Frans P Nijkamp
The role of sensory nerve endings in nerve growth factor-induced airway hyperresponsiveness to histamine in guinea-pigs.
British journal of pharmacology 2001;134(4):771-6.
2001: R B R Muijsers; Ingrid van Ark; Gert Folkerts; Andries Koster; Antoon J M Van Oosterhout; Dirkje S Postma; Frans P Nijkamp
Apocynin and 1400 W prevents airway hyperresponsiveness during allergic reactions in mice.
British journal of pharmacology 2001;134(2):434-40.
2001: Aletta D Kraneveld; Frans P Nijkamp
Tachykinins and neuro-immune interactions in asthma.
International immunopharmacology 2001;1(9-10):1629-50.
2001: Robert Ten Broeke; Gert Folkerts; Thea Leusink-Muis; HJ Van Der Linde; Matteo Villain; MK Manion; Fred De Clerck; J Edwin Blalock; Frans P Nijkamp
Calcium sensors as new therapeutic targets for airway hyperresponsiveness and asthma.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(10):1831-3.
2001: Gert Folkerts; Dicky van Heuven-Nolsen; Frans P Nijkamp
Bradykinin causes inhibition of methacholine-induced bronchoconstriction in vivo in mice.
Naunyn-Schmiedeberg's archives of pharmacology 2001;364(1):53-8.
2001: René Houtman; Andries Koster; Frans P Nijkamp
Integrin VLA-5: modulator and activator of mast cells.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2001;31(6):817-22.
2001: Gert Folkerts; Joris Kloek; P Geppetti; HJ Van Der Linde; Frans P Nijkamp
Factors that determine acetylcholine responsiveness of guinea pig tracheal tubes.
European journal of pharmacology 2001;420(2-3):151-7.
2001: Rob Ruijtenbeek; John A W Kruijtzer; W van de Wiel; Marcel J E Fischer; M Flück; Frank A Redegeld; Rob M J Liskamp; Frans P Nijkamp
Peptoid - peptide hybrids that bind Syk SH2 domains involved in signal transduction.
Chembiochem : a European journal of chemical biology 2001;2(3):171-9.
2001: René Houtman; Robert Ten Broeke; J Edwin Blalock; Matteo Villain; Andries Koster; Frans P Nijkamp
Attenuation of very late antigen-5-mediated adhesion of bone marrow-derived mast cells to fibronectin by peptides with inverted hydropathy to EF-hands.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(2):861-7.
2001: P A J Henricks; Frans P Nijkamp
Reactive oxygen species as mediators in asthma.
Pulmonary pharmacology & therapeutics 2001;14(6):409-20.
2000: edith janssen; Antoon J M Van Oosterhout; Frans P Nijkamp; Willem van Eden; Marca H M Wauben
The efficacy of immunotherapy in an experimental murine model of allergic asthma is related to the strength and site of T cell activation during immunotherapy.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(12):7207-14.
2000: Antoon J M Van Oosterhout; Joris de Bie; Frans P Nijkamp
Novel immunopharmacological strategies for allergic asthma.
Current opinion in investigational drugs (London, England : 2000) 2000;1(2):214-8.
2000: Joris de Bie; M Kneepkens; Aletta D Kraneveld; EH Jonker; P A J Henricks; Frans P Nijkamp; Antoon J M Van Oosterhout
Absence of late airway response despite increased airway responsiveness and eosinophilia in a murine model of asthma.
Experimental lung research 2000;26(7):491-507.
2000: Aletta D Kraneveld; D E James; Annick de Vries; Frans P Nijkamp
Excitatory non-adrenergic-non-cholinergic neuropeptides: key players in asthma.
European journal of pharmacology 2000;405(1-3):113-29.
2000: Khalil Karimi; Frank A Redegeld; R Blom; Frans P Nijkamp
Stem cell factor and interleukin-4 increase responsiveness of mast cells to substance P.
Experimental hematology 2000;28(6):626-34.
2000: R B R Muijsers; Edwin van den Worm; Gert Folkerts; CJ Beukelman; Andries Koster; Dirkje S Postma; Frans P Nijkamp
Apocynin inhibits peroxynitrite formation by murine macrophages.
British journal of pharmacology 2000;130(4):932-6.
2000: Gert Folkerts; J W Vlieger; Annick de Vries; S Faas; HJ Van Der Linde; Ferdi Engels; J C de Jong; F A Verheyen; Dicky van Heuven-Nolsen; Frans P Nijkamp
Virus- and bradykinin-induced airway hyperresponsiveness in guinea pigs.
American journal of respiratory and critical care medicine 2000;161(5):1666-71.
2000: edith janssen; Antoon J M Van Oosterhout; AJ van Rensen; Willem van Eden; Frans P Nijkamp; Marca H M Wauben
Modulation of Th2 responses by peptide analogues in a murine model of allergic asthma: amelioration or deterioration of the disease process depends on the Th1 or Th2 skewing characteristics of the therapeutic peptide.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(2):580-8.
1999: Joris de Bie; P A J Henricks; William W Cruikshank; Gerard A Hofman; Frans P Nijkamp; Antoon J M Van Oosterhout
Effect of interleukin-16-blocking peptide on parameters of allergic asthma in a murine model.
European journal of pharmacology 1999;383(2):189-96.
1999: Anneke H van Houwelingen; L A van der Avoort; D Heuven-Nolsen; Aletta D Kraneveld; Frans P Nijkamp
Repeated challenge with dinitrobenzene sulphonic acid in dinitrofluorobenzene-sensitized mice results in vascular hyperpermeability in the trachea: a role for tachykinins.
British journal of pharmacology 1999;127(7):1583-8.
1999: edith janssen; Marca H M Wauben; EH Jonker; Gerard A Hofman; Willem van Eden; Frans P Nijkamp; Antoon J M Van Oosterhout
Opposite effects of immunotherapy with ovalbumin and the immunodominant T-cell epitope on airway eosinophilia and hyperresponsiveness in a murine model of allergic asthma.
American journal of respiratory cell and molecular biology 1999;21(1):21-9.
1999: A Leusink-Muis; Robert Ten Broeke; Gert Folkerts; Fred De Clerck; Frans P Nijkamp
Betamethasone prevents virus-induced airway inflammation but not airway hyperresponsiveness in guinea pigs.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1999;29 Suppl 2():82-5.
1999: J Scheerens; Gert Folkerts; HJ Van Der Linde; P J Sterk; D M Conroy; T J Williams; Frans P Nijkamp
Eotaxin levels and eosinophils in guinea pig broncho-alveolar lavage fluid are increased at the onset of a viral respiratory infection.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1999;29 Suppl 2():74-7.
1999: Annick de Vries; M C Dessing; Ferdi Engels; P A J Henricks; Frans P Nijkamp
Nerve growth factor induces a neurokinin-1 receptor- mediated airway hyperresponsiveness in guinea pigs.
American journal of respiratory and critical care medicine 1999;159(5 Pt 1):1541-4.
1999: Khalil Karimi; Frank A Redegeld; Bianca M Heijdra; Frans P Nijkamp
Stem cell factor and interleukin-4 induce murine bone marrow cells to develop into mast cells with connective tissue type characteristics in vitro.
Experimental hematology 1999;27(4):654-62.
1999: H Scheerens; T L Buckley; TL Muis; Johan Garssen; J Dormans; Frans P Nijkamp; Henk Van Loveren
Long-term topical exposure to toluene diisocyanate in mice leads to antibody production and in vivo airway hyperresponsiveness three hours after intranasal challenge.
American journal of respiratory and critical care medicine 1999;159(4 Pt 1):1074-80.
1999: Dicky van Heuven-Nolsen; Sjef De Kimpe; TL Muis; Ingrid van Ark; HF Savelkoul; R B Beems; Antoon J M Van Oosterhout; Frans P Nijkamp
Opposite role of interferon-gamma and interleukin-4 on the regulation of blood pressure in mice.
Biochemical and biophysical research communications 1999;254(3):816-20.
1998: CL Hofstra; Ingrid van Ark; HF Savelkoul; William W Cruikshank; Frans P Nijkamp; Antoon J M Van Oosterhout
Vbeta8+ T lymphocytes are essential in the regulation of airway hyperresponsiveness and bronchoalveolar eosinophilia but not in allergen-specific IgE in a murine model of allergic asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1998;28(12):1571-80.
1998: G Sadeghi-Hashjin; Gert Folkerts; P A J Henricks; R B R Muijsers; Frans P Nijkamp
Peroxynitrite in airway diseases.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1998;28(12):1464-73.
1998: CL Hofstra; Ingrid van Ark; Gerard A Hofman; Frans P Nijkamp; P M Jardieu; Antoon J M Van Oosterhout
Differential effects of endogenous and exogenous interferon-gamma on immunoglobulin E, cellular infiltration, and airway responsiveness in a murine model of allergic asthma.
American journal of respiratory cell and molecular biology 1998;19(5):826-35.
1998: CL Hofstra; Ingrid van Ark; Gerard A Hofman; Mirjam Kool; Frans P Nijkamp; Antoon J M Van Oosterhout
Prevention of Th2-like cell responses by coadministration of IL-12 and IL-18 is associated with inhibition of antigen-induced airway hyperresponsiveness, eosinophilia, and serum IgE levels.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(9):5054-60.
1998: Antoon J M Van Oosterhout; Betty C A M van Esch; Gerard A Hofman; CL Hofstra; Ingrid van Ark; Frans P Nijkamp; Martien L Kapsenberg; HF Savelkoul; F R Weller
Allergen immunotherapy inhibits airway eosinophilia and hyperresponsiveness associated with decreased IL-4 production by lymphocytes in a murine model of allergic asthma.
American journal of respiratory cell and molecular biology 1998;19(4):622-8.
1998: Joris de Bie; P A J Henricks; William W Cruikshank; Gerard A Hofman; EH Jonker; Frans P Nijkamp; Antoon J M Van Oosterhout
Modulation of airway hyperresponsiveness and eosinophilia by selective histamine and 5-HT receptor antagonists in a mouse model of allergic asthma.
British journal of pharmacology 1998;124(5):857-64.
1998: Gert Folkerts; W W Busse; Frans P Nijkamp; Ronald L Sorkness; J E Gern
Virus-induced airway hyperresponsiveness and asthma.
American journal of respiratory and critical care medicine 1998;157(6 Pt 1):1708-20.
1998: Aletta D Kraneveld; TL Muis; Andries Koster; Frans P Nijkamp
Role of mucosal mast cells in early vascular permeability changes of intestinal DTH reaction in the rat.
The American journal of physiology 1998;274(5 Pt 1):G832-9.
1998: Ferdi Engels; Frans P Nijkamp
Pharmacological inhibition of leukotriene actions.
Pharmacy world & science : PWS 1998;20(2):60-5.
1998: Edith M Hessel; William W Cruikshank; Ingrid van Ark; Joris de Bie; Betty C A M van Esch; Gerard A Hofman; Frans P Nijkamp; David M Center; Antoon J M Van Oosterhout
Involvement of IL-16 in the induction of airway hyper-responsiveness and up-regulation of IgE in a murine model of allergic asthma.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(6):2998-3005.
1998: P A J Henricks; Frans P Nijkamp
Pharmacological modulation of cell adhesion molecules.
European journal of pharmacology 1998;344(1):1-13.
1998: J F Westra-De Vlieger; P W Van Den Wijngaard; Andries Koster; J Wilting; J Leysen; Dicky van Heuven-Nolsen; Frans P Nijkamp
The tachykinin NK1 receptor antagonist, RP67580, inhibits the bradykinin-induced rise in intracellular Ca2+ concentration in bovine pulmonary artery endothelial cells.
European journal of pharmacology 1998;342(2-3):359-66.
1998: G Sadeghi-Hashjin; P A J Henricks; Gert Folkerts; TL Muis; J Garssen; Frans P Nijkamp
Role of the epithelial layer in the generation of superoxide anion by the guinea-pig isolated trachea.
Mediators of inflammation 1998;7(1):35-40.
1997: Aletta D Kraneveld; Gert Folkerts; Antoon J M Van Oosterhout; Frans P Nijkamp
Airway hyperresponsiveness: first eosinophils and then neuropeptides.
International journal of immunopharmacology 1997;19(9-10):517-27.
1997: Antoon J M Van Oosterhout; CL Hofstra; R Shields; B Chan; Ingrid van Ark; P M Jardieu; Frans P Nijkamp
Murine CTLA4-IgG treatment inhibits airway eosinophilia and hyperresponsiveness and attenuates IgE upregulation in a murine model of allergic asthma.
American journal of respiratory cell and molecular biology 1997;17(3):386-92.
1997: Aletta D Kraneveld; Frans P Nijkamp; Antoon J M Van Oosterhout
Role for neurokinin-2 receptor in interleukin-5-induced airway hyperresponsiveness but not eosinophilia in guinea pigs.
American journal of respiratory and critical care medicine 1997;156(2 Pt 1):367-74.
1997: Aletta D Kraneveld; Ingrid van Ark; HJ Van Der Linde; D Fattah; Frans P Nijkamp; Antoon J M Van Oosterhout
Antibody to very late activation antigen 4 prevents interleukin-5-induced airway hyperresponsiveness and eosinophil infiltration in the airways of guinea pigs.
The Journal of allergy and clinical immunology 1997;100(2):242-50.
1997: Dicky van Heuven-Nolsen; J F Westra-De Vlieger; TL Muis; J H Denee; T O Rivas; Frans P Nijkamp
Pharmacology and mode of action of bradykinin on mouse-isolated trachea.
Naunyn-Schmiedeberg's archives of pharmacology 1997;356(1):134-8.
1997: Frank A Redegeld; Bianca M Heijdra; M C Knippels; Johan Garssen; Frans P Nijkamp
Nitric oxide production by macrophages stimulated by antigen-binding T-cell factors.
Immunology letters 1997;57(1-3):147-9.
1997: Roel A van Nieuwstadt; P A J Henricks; R Hajer; W A van der Meer van Roomen; Henk J Breukink; Frans P Nijkamp
Characterization of muscarinic receptors in equine tracheal smooth muscle in vitro.
The Veterinary quarterly 1997;19(2):54-7.
1997: PG Bloemen; M C van den Tweel; P A J Henricks; Ferdi Engels; M H Kester; P G van de Loo; F J Blomjous; Frans P Nijkamp
Increased cAMP levels in stimulated neutrophils inhibit their adhesion to human bronchial epithelial cells.
The American journal of physiology 1997;272(4 Pt 1):L580-7.
1997: Edith M Hessel; Antoon J M Van Oosterhout; Ingrid van Ark; Betty C A M van Esch; Gerard A Hofman; Henk Van Loveren; HF Savelkoul; Frans P Nijkamp
Development of airway hyperresponsiveness is dependent on interferon-gamma and independent of eosinophil infiltration.
American journal of respiratory cell and molecular biology 1997;16(3):325-34.
1997: PG Bloemen; P A J Henricks; Frans P Nijkamp
Cell adhesion molecules and asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1997;27(2):128-41.
1997: P A J Henricks; PG Bloemen; Frans P Nijkamp
Adhesion molecules and the recruitment of eosinophils to the airways.
Research in immunology 1997;148(1):18-28.
1997: R B R Muijsers; Gert Folkerts; P A J Henricks; G Sadeghi-Hashjin; Frans P Nijkamp
Peroxynitrite: a two-faced metabolite of nitric oxide.
Life sciences 1997;60(21):1833-45.
1996: H Scheerens; T L Buckley; TL Muis; Henk Van Loveren; Frans P Nijkamp
The involvement of sensory neuropeptides in toluene diisocyanate-induced tracheal hyperreactivity in the mouse airways.
British journal of pharmacology 1996;119(8):1665-71.
1996: Joris de Bie; Edith M Hessel; Ingrid van Ark; Betty C A M van Esch; Gerard A Hofman; Frans P Nijkamp; Antoon J M Van Oosterhout
Effect of dexamethasone and endogenous corticosterone on airway hyperresponsiveness and eosinophilia in the mouse.
British journal of pharmacology 1996;119(7):1484-90.
1996: G Sadeghi-Hashjin; P A J Henricks; Gert Folkerts; A K Verheyen; H J van der Linde; Frans P Nijkamp
Bovine tracheal responsiveness in vitro: role of the epithelium and nitric oxide.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1996;9(11):2286-93.
1996: T L Buckley; PG Bloemen; P A J Henricks; M C van den Tweel; Frank A Redegeld; Andries Koster; Frans P Nijkamp
LFA-1 and ICAM-1 are crucial for the induction of hyperreactivity in the mouse airways.
Annals of the New York Academy of Sciences 1996;796():149-61.
1996: H Scheerens; T L Buckley; E M Davidse; Johan Garssen; Frans P Nijkamp; Henk Van Loveren
Toluene diisocyanate-induced in vitro tracheal hyperreactivity in the mouse.
American journal of respiratory and critical care medicine 1996;154(4 Pt 1):858-65.
1996: Ferdi Engels; Roger Kessels; P A J Henricks; Frans P Nijkamp
Preferential formation of 13-hydroxylinoleic acid by human peripheral blood eosinophils.
Prostaglandins 1996;52(2):117-24.
1996: G Sadeghi-Hashjin; Gert Folkerts; P A J Henricks; P G van de Loo; I E Dik; Frans P Nijkamp
Relaxation of guinea-pig trachea by sodium nitroprusside: cyclic GMP and nitric oxide not involved.
British journal of pharmacology 1996;118(3):466-70.
1996: G Sadeghi-Hashjin; Gert Folkerts; P A J Henricks; A K Verheyen; H J van der Linde; Ingrid van Ark; A Coene; Frans P Nijkamp
Peroxynitrite induces airway hyperresponsiveness in guinea pigs in vitro and in vivo.
American journal of respiratory and critical care medicine 1996;153(5):1697-701.
1996: G Sadeghi-Hashjin; Gert Folkerts; P A J Henricks; P G Van de Loo; H J Van der Linde; I E Dik; Frans P Nijkamp
Induction of guinea pig airway hyperresponsiveness by inactivation of guanylate cyclase.
European journal of pharmacology 1996;302(1-3):109-15.
1996: I C Mohede; Ingrid van Ark; F M Brons; Antoon J M Van Oosterhout; Frans P Nijkamp
Salmeterol inhibits interferon-gamma and interleukin-4 production by human peripheral blood mononuclear cells.
International journal of immunopharmacology 1996;18(3):193-201.
1996: Antoon J M Van Oosterhout; Ingrid van Ark; Gerard A Hofman; H J Van Der Linde; D Fattah; Frans P Nijkamp
Role of interleukin-5 and substance P in development of airway hyperreactivity to histamine in guinea-pigs.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1996;9(3):493-9.
1996: PG Bloemen; T L Buckley; M C van den Tweel; P A J Henricks; Frank A Redegeld; Andries Koster; Frans P Nijkamp
LFA-1, and not Mac-1, is crucial for the development of hyperreactivity in a murine model of nonallergic asthma.
American journal of respiratory and critical care medicine 1996;153(2):521-9.
1996: PG Bloemen; M C Van den Tweel; P A J Henricks; Ferdi Engels; M J Van de Velde; F J Blomjous; Frans P Nijkamp
Stimulation of both human bronchial epithelium and neutrophils is needed for maximal interactive adhesion.
The American journal of physiology 1996;270(1 Pt 1):L80-7.
1995: Edith M Hessel; Antoon J M Van Oosterhout; CL Hofstra; Joris de Bie; Johan Garssen; Henk Van Loveren; A K Verheyen; HF Savelkoul; Frans P Nijkamp
Bronchoconstriction and airway hyperresponsiveness after ovalbumin inhalation in sensitized mice.
European journal of pharmacology 1995;293(4):401-12.
1995: Edith M Hessel; A Zwart; E Oostveen; Antoon J M Van Oosterhout; D I Blyth; Frans P Nijkamp
Repeated measurement of respiratory function and bronchoconstriction in unanesthetized mice.
Journal of applied physiology (Bethesda, Md. : 1985) 1995;79(5):1711-6.
1995: Gert Folkerts; H Van der Linde; P G Van de Loo; Ferdi Engels; Frans P Nijkamp
Leukotrienes mediate tracheal hyperresponsiveness after nitric oxide synthesis inhibition.
European journal of pharmacology 1995;285(2):R1-2.
1995: J Buijs; M W Egbers; Frans P Nijkamp
Toxocara canis-induced airway eosinophilia and tracheal hyporeactivity in guinea pigs and mice.
European journal of pharmacology 1995;293(3):207-15.
1995: G S Hashjin; P A J Henricks; Gert Folkerts; Frans P Nijkamp
Preparation of bovine tracheal smooth muscle for in vitro pharmacological studies.
Journal of pharmacological and toxicological methods 1995;34(2):103-8.
1995: T L Buckley; Johan Garssen; B Kerkhoff; Frans P Nijkamp; Henk Van Loveren
LCB 2183 inhibits tracheal hyperreactivity and pulmonary inflammation in mouse airways.
European journal of pharmacology 1995;282(1-3):103-9.
1995: M J van de Velde; Ferdi Engels; P A J Henricks; PG Bloemen; Frans P Nijkamp
The linoleic acid metabolite 13-HODE modulates degranulation of human polymorphonuclear leukocytes.
FEBS letters 1995;369(2-3):301-4.
1995: Gert Folkerts; H van der Linde; A K Verheyen; Frans P Nijkamp
Endogenous nitric oxide modulation of potassium-induced changes in guinea-pig airway tone.
British journal of pharmacology 1995;115(7):1194-8.
1995: Dicky van Heuven-Nolsen; TL Muis; Ferdi Engels; P A J Henricks; T L Buckley; Frans P Nijkamp
Hypotensive effect of 13-hydroxylinoleic acid in the rat: mediation via the release of a CGRP-like mediator from capsaicin-sensitive nerves.
British journal of pharmacology 1995;115(5):835-9.
1995: P A J Henricks; Ferdi Engels; H J van der Linde; Johan Garssen; Frans P Nijkamp
13-Hydroxy-linoleic acid induces airway hyperresponsiveness to histamine and methacholine in guinea pigs in vivo.
The Journal of allergy and clinical immunology 1995;96(1):36-43.
1995: Antoon J M Van Oosterhout; D Fattah; Ingrid van Ark; Gerard A Hofman; T L Buckley; Frans P Nijkamp
Eosinophil infiltration precedes development of airway hyperreactivity and mucosal exudation after intranasal administration of interleukin-5 to mice.
The Journal of allergy and clinical immunology 1995;96(1):104-12.
1995: A R Ladenius; Gert Folkerts; H J van der Linde; Frans P Nijkamp
Potentiation by viral respiratory infection of ovalbumin-induced guinea-pig tracheal hyperresponsiveness: role for tachykinins.
British journal of pharmacology 1995;115(6):1048-52.
1995: Gert Folkerts; Frans P Nijkamp
Virus-induced airway hyperresponsiveness. Role of inflammatory cells and mediators.
American journal of respiratory and critical care medicine 1995;151(5):1666-73; discussion 1673-4.
1995: Aletta D Kraneveld; T L Buckley; Dicky van Heuven-Nolsen; Y van Schaik; Andries Koster; Frans P Nijkamp
Delayed-type hypersensitivity-induced increase in vascular permeability in the mouse small intestine: inhibition by depletion of sensory neuropeptides and NK1 receptor blockade.
British journal of pharmacology 1995;114(7):1483-9.
1995: J Buijs; M W Egbers; W H Lokhorst; HF Savelkoul; Frans P Nijkamp
Toxocara-induced eosinophilic inflammation. Airway function and effect of anti-IL-5.
American journal of respiratory and critical care medicine 1995;151(3 Pt 1):873-8.
1995: PG Bloemen; P A J Henricks; L van Bloois; M C van den Tweel; A C Bloem; Frans P Nijkamp; Daan J A Crommelin; Gert Storm
Adhesion molecules: a new target for immunoliposome-mediated drug delivery.
FEBS letters 1995;357(2):140-4.
1995: Gert Folkerts; H J van der Linde; Frans P Nijkamp
Virus-induced airway hyperresponsiveness in guinea pigs is related to a deficiency in nitric oxide.
The Journal of clinical investigation 1995;95(1):26-30.
1995: Antoon J M Van Oosterhout; Ingrid van Ark; Gert Folkerts; H J van der Linde; HF Savelkoul; A K Verheyen; Frans P Nijkamp
Antibody to interleukin-5 inhibits virus-induced airway hyperresponsiveness to histamine in guinea pigs.
American journal of respiratory and critical care medicine 1995;151(1):177-83.
1995: Ferdi Engels; A H van Houwelingen; T L Buckley; M J van de Velde; P A J Henricks; Frans P Nijkamp
Airway hyperresponsiveness induced by 13-hydroxyoctadecadienoic acid (13-HODE) is mediated by sensory neuropeptides.
Advances in prostaglandin, thromboxane, and leukotriene research 1995;23():361-3.
1994: T L Buckley; Frans P Nijkamp
Mucosal exudation associated with a pulmonary delayed-type hypersensitivity reaction in the mouse. Role for the tachykinins.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(9):4169-78.
1994: Frans P Nijkamp; Gert Folkerts
Nitric oxide and bronchial reactivity.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1994;24(10):905-14.
1994: Sjef De Kimpe; W Tielemans; Dicky van Heuven-Nolsen; Frans P Nijkamp
Reversal of bradykinin-induced relaxation to contraction after interferon-gamma in bovine isolated mesenteric arteries.
European journal of pharmacology 1994;261(1-2):111-20.
1994: M J van de Velde; Ferdi Engels; P A J Henricks; Frans P Nijkamp
13-HODE inhibits the intracellular calcium increase of activated human polymorphonuclear cells.
Journal of leukocyte biology 1994;56(2):200-2.
1994: Aletta D Kraneveld; Andries Koster; Frans P Nijkamp
Microvascular permeability in isolated vascularly perfused small intestine of rats.
The American journal of physiology 1994;266(6 Pt 1):G1170-8.
1994: T L Buckley; Frans P Nijkamp
Airways hyperreactivity and cellular accumulation in a delayed-type hypersensitivity reaction in the mouse. Modulation by capsaicin-sensitive nerves.
American journal of respiratory and critical care medicine 1994;149(2 Pt 1):400-7.
1994: Sjef De Kimpe; Dicky van Heuven-Nolsen; J G C van Amsterdam; M W Radomski; Frans P Nijkamp
Induction of nitric oxide release by interferon-gamma inhibits vasodilation and cyclic GMP increase in bovine isolated mesenteric arteries.
The Journal of pharmacology and experimental therapeutics 1994;268(2):910-5.
1994: J Buijs; W H Lokhorst; J Robinson; Frans P Nijkamp
Toxocara canis-induced murine pulmonary inflammation: analysis of cells and proteins in lung tissue and bronchoalveolar lavage fluid.
Parasite immunology 1994;16(1):1-9.
1993: P A J Henricks; Betty C A M van Esch; Ferdi Engels; Frans P Nijkamp
Effects of parainfluenza type 3 virus on guinea pig pulmonary alveolar macrophage functions in vitro.
Inflammation 1993;17(6):663-75.
1993: PG Bloemen; M C van den Tweel; P A J Henricks; Ferdi Engels; S S Wagenaar; A A Rutten; Frans P Nijkamp
Expression and modulation of adhesion molecules on human bronchial epithelial cells.
American journal of respiratory cell and molecular biology 1993;9(6):586-93.
1993: Frans P Nijkamp; H J van der Linde; Gert Folkerts
Nitric oxide synthesis inhibitors induce airway hyperresponsiveness in the guinea pig in vivo and in vitro. Role of the epithelium.
The American review of respiratory disease 1993;148(3):727-34.
1993: Gert Folkerts; H J van der Linde; C Omini; Frans P Nijkamp
Virus-induced airway inflammation and hyperresponsiveness in the guinea-pig is inhibited by levodropropizine.
Naunyn-Schmiedeberg's archives of pharmacology 1993;348(2):213-9.
1993: Antoon J M Van Oosterhout; Ingrid van Ark; Gerard A Hofman; HF Savelkoul; Frans P Nijkamp
Recombinant interleukin-5 induces in vivo airway hyperresponsiveness to histamine in guinea pigs.
European journal of pharmacology 1993;236(3):379-83.
1993: Gert Folkerts; A K Verheyen; G M Geuens; H F Folkerts; Frans P Nijkamp
Virus-induced changes in airway responsiveness, morphology, and histamine levels in guinea pigs.
The American review of respiratory disease 1993;147(6 Pt 1):1569-77.
1993: Johan Garssen; Henk Van Loveren; C M Gierveld; H Van der Vliet; Frans P Nijkamp
Functional characterization of muscarinic receptors in murine airways.
British journal of pharmacology 1993;109(1):53-60.
1993: Sjef De Kimpe; Dicky van Heuven-Nolsen; Frans P Nijkamp
Acetylcholine-induced relaxation in bovine isolated mesenteric arteries is suppressed by polymorphonuclear leukocytes.
British journal of pharmacology 1993;109(1):8-13.
1993: A R Ladenius; Frans P Nijkamp
Capsaicin pretreatment of guinea pigs in vivo prevents ovalbumin-induced tracheal hyperreactivity in vitro.
European journal of pharmacology 1993;235(1):127-31.
1993: Gert Folkerts; F De Clerck; I Reijnart; P Span; Frans P Nijkamp
Virus-induced airway hyperresponsiveness in the guinea-pig: possible involvement of histamine and inflammatory cells.
British journal of pharmacology 1993;108(4):1083-93.
1993: Antoon J M Van Oosterhout; A R Ladenius; HF Savelkoul; Ingrid van Ark; K C Delsman; Frans P Nijkamp
Effect of anti-IL-5 and IL-5 on airway hyperreactivity and eosinophils in guinea pigs.
The American review of respiratory disease 1993;147(3):548-52.
1993: Johan Garssen; Henk Van Loveren; H Van Der Vliet; H Bot; Frans P Nijkamp
T cell-mediated induction of airway hyperresponsiveness and altered lung functions in mice are independent of increased vascular permeability and mononuclear cell infiltration.
The American review of respiratory disease 1993;147(2):307-13.
1993: D M Veenstra; K J van Buuren; M J Krielaart; Frans P Nijkamp
Errors introduced in radioligand binding studies due to displaceable, cation dependent, [3H]prazosin binding to glass-fibre filters and glass surfaces.
Journal of receptor research 1993;13(5):801-14.
1993: Frans P Nijkamp
Beta-adrenergic receptors in the lung: an introduction.
Life sciences 1993;52(26):2073-82.
1993: W B Stam; Antoon J M Van Oosterhout; Frans P Nijkamp
Pharmacologic modulation of Th1- and Th2-associated lymphokine production.
Life sciences 1993;53(26):1921-34.
1992: Gert Folkerts; Betty C A M van Esch; M Janssen; Frans P Nijkamp
Virus-induced airway hyperresponsiveness in guinea pigs in vivo: study of broncho-alveolar cell number and activity.
European journal of pharmacology 1992;228(4):219-27.
1992: D M Veenstra; K J van Buuren; Frans P Nijkamp
Determination of alpha 1-adrenoceptor subtype selectivity by [3H]-prazosin displacement studies in guinea-pig cerebral cortex and rat spleen membranes.
British journal of pharmacology 1992;107(1):202-6.
1992: Gert Folkerts; A Verheyen; M Janssen; Frans P Nijkamp
Virus-induced airway hyperresponsiveness in the guinea pig can be transferred by bronchoalveolar cells.
The Journal of allergy and clinical immunology 1992;90(3 Pt 1):364-72.
1992: Antoon J M Van Oosterhout; W B Stam; R G Vanderschueren; Frans P Nijkamp
Effects of cytokines on beta-adrenoceptor function of human peripheral blood mononuclear cells and guinea pig trachea.
The Journal of allergy and clinical immunology 1992;90(3 Pt 1):340-8.
1992: Gert Folkerts; A Verheyen; Frans P Nijkamp
Viral infection in guinea pigs induces a sustained non-specific airway hyperresponsiveness and morphological changes of the respiratory tract.
European journal of pharmacology 1992;228(2-3):121-30.
1992: T L Buckley; M J Van de Velde; P A J Henricks; Ferdi Engels; Frans P Nijkamp
13-hydroxyoctadecadienoic acid attenuates oedema formation induced by leukotriene B4 in vivo in rabbit skin.
European journal of pharmacology 1992;218(2-3):369-72.
1992: P A J Henricks; G J Binkhorst; A A Drijver; Frans P Nijkamp
Pasteurella haemolytica leukotoxin enhances production of leukotriene B4 and 5-hydroxyeicosatetraenoic acid by bovine polymorphonuclear leukocytes.
Infection and immunity 1992;60(8):3238-43.
1992: Marcel J E Fischer; A J van Oosterhout; LH Janssen; Frans P Nijkamp
Effect of albumin on adenylate cyclase receptor-related signal transduction of human peripheral blood mononuclear cells.
Biochemical pharmacology 1992;44(2):351-8.
1992: Ferdi Engels; B F Renirie; B A Hart; R P Labadie; Frans P Nijkamp
Effects of apocynin, a drug isolated from the roots of Picrorhiza kurroa, on arachidonic acid metabolism.
FEBS letters 1992;305(3):254-6.
1992: Frans P Nijkamp; Ferdi Engels; P A J Henricks; Antoon J M Van Oosterhout
Mechanisms of beta-adrenergic receptor regulation in lungs and its implications for physiological responses.
Physiological reviews 1992;72(2):323-67.
1992: Sjef De Kimpe; Dicky van Heuven-Nolsen; Frans P Nijkamp
Bovine polymorphonuclear leukocytes increase sensitivity to noradrenaline in isolated mesenteric arteries.
British journal of pharmacology 1992;105(3):581-6.
1992: Frans P Nijkamp; Roger Kessels; Dicky van Heuven-Nolsen; P Braquet
Reversal of the endotoxin-induced bronchial hyperreactivity to histamine by the platelet activating factor antagonist BN 52021.
Pneumonologia i alergologia polska 1992;60 Suppl 2():105-7.
1991: Antoon J M Van Oosterhout; Gerard A Hofman; F M Woutersen-Van Nijnanten; Frans P Nijkamp
5-HT1-like receptors mediate potentiation of cholinergic nerve-mediated contraction of isolated mouse trachea.
European journal of pharmacology 1991;209(3):237-44.
1991: Ferdi Engels; Roger Kessels; A J Schreurs; Frans P Nijkamp
Production of arachidonic acid and linoleic acid metabolites by human bronchoalveolar lavage cells.
Prostaglandins 1991;42(5):441-50.
1991: Antoon J M Van Oosterhout; L Celeda; K C Delsman; D de Wied; Frans P Nijkamp
Epithelium-dependent potentiation of anaphylactic contractions by beta-endorphin in tracheae isolated from actively sensitized guinea-pigs.
British journal of pharmacology 1991;103(2):1470-4.
1991: P A J Henricks; Ferdi Engels; H J Van der Linde; Frans P Nijkamp
13-hydroxy-linoleic acid induces airway hyperreactivity to histamine in guinea-pigs.
European journal of pharmacology 1991;197(2-3):233-4.
1991: Antoon J M Van Oosterhout; F M Woutersen-Van Nijnanten; Frans P Nijkamp
Effect of cyclosporin-A treatment on endotoxin-induced airway hyperreactivity in vivo and in vitro in guinea-pigs.
Naunyn-Schmiedeberg's archives of pharmacology 1991;343(5):542-5.
1991: P A J Henricks; Ferdi Engels; H van der Vliet; Frans P Nijkamp
9- and 13-hydroxy-linoleic acid possess chemotactic activity for bovine and human polymorphonuclear leukocytes.
Prostaglandins 1991;41(1):21-7.
1990: G J Binkhorst; P A J Henricks; T S vd Ingh; R Hajer; Frans P Nijkamp
The effect of stress on host defense system and on lung damage in calves experimentally infected with Pasteurella haemolytica type A1.
Zentralblatt für Veterinärmedizin. Reihe A 1990;37(7):525-36.
1990: M J Oosthuizen; Ferdi Engels; Betty C A M van Esch; P A J Henricks; Frans P Nijkamp
Production of arachidonic and linoleic acid metabolites by guinea pig tracheal epithelial cells.
Inflammation 1990;14(4):401-8.
1990: P A J Henricks; F J Grommers; H van der Vliet; D van de Geer; Frans P Nijkamp
The influence of mononuclear leukocytes on the chemotactic responsiveness of polymorphonuclear leukocytes of bovines.
Zentralblatt für Veterinärmedizin. Reihe B. Journal of veterinary medicine. Series B 1990;37(5):332-6.
1990: Dicky van Heuven-Nolsen; G A Ten Have; Frans P Nijkamp
Interaction between neutrophils and pig coronary artery increases histamine contractions.
Agents and actions 1990;30(1-2):195-7.
1990: Gert Folkerts; Frans P Nijkamp
Parainfluenza-3 infection of the guinea pig airways induces respiratory airway hyperreactivity in vitro.
Agents and actions 1990;30(1-2):261-3.
1990: Antoon J M Van Oosterhout; L Celeda; D de Wied; Frans P Nijkamp
Beta-endorphin modulates anaphylactic contractions of tracheae isolated from actively sensitized guinea pigs.
Agents and actions 1990;30(1-2):89-91.
1990: P A J Henricks; G J Binkhorst; A A Drijver; H Van der Vliet; Frans P Nijkamp
The effect of Pasteurella haemolytica cytotoxin on bovine polymorphonuclear leukocytes can be attenuated by beta-adrenoceptor antagonists.
Veterinary microbiology 1990;22(2-3):259-66.
1990: Frans P Nijkamp; P A J Henricks
Receptors in airway disease. Beta-adrenoceptors in lung inflammation.
The American review of respiratory disease 1990;141(3 Pt 2):S145-50.
1990: Ferdi Engels; A A Drijver; Frans P Nijkamp
Modulation of the release of 9-hydroxy-octadecadienoic acid and other fatty acid derived mediators from guinea-pig pulmonary macrophages.
International journal of immunopharmacology 1990;12(2):199-205.
1990: Johan Garssen; Henk Van Loveren; H van der Vliet; Frans P Nijkamp
T cell mediated induction of bronchial hyperreactivity.
British journal of clinical pharmacology 1990;30 Suppl 1():153S-155S.
1990: Antoon J M Van Oosterhout; Frans P Nijkamp
Lymphocytes and bronchial hyperresponsiveness.
Life sciences 1990;46(18):1255-64.
1990: Gert Folkerts; M Janssen; Frans P Nijkamp
Parainfluenza-3 induced hyperreactivity of the guinea pig trachea coincides with an increased number of bronchoalveolar cells.
British journal of clinical pharmacology 1990;30 Suppl 1():159S-161S.
1990: Antoon J M Van Oosterhout; Frans P Nijkamp
Effect of lymphokines on beta-adrenoceptor function of human peripheral blood mononuclear cells.
British journal of clinical pharmacology 1990;30 Suppl 1():150S-152S.
1990: Antoon J M Van Oosterhout; Frans P Nijkamp
Effect of human interleukin-2 from different sources on lymphocyte and airway beta-adrenoceptor function.
International journal of immunopharmacology 1990;12(4):409-12.
1990: Dicky van Heuven-Nolsen; G A Ten Have; Frans P Nijkamp
Neutrophils increase histamine contractions in pig coronary artery: a role for lipoxygenase products.
British journal of clinical pharmacology 1990;30 Suppl 1():156S-158S.
1990: J Buijs; M W Egbers; Frans P Nijkamp
Toxocara canis-induced airway hyporeactivity in mice.
Agents and actions. Supplements 1990;31():75-80.
1990: P A J Henricks; F Engles; Betty C A M van Esch; H J van der Linde; M J Oosthuizen; Frans P Nijkamp
Epithelium-derived linoleic acid metabolites modulate airway smooth muscle function.
Agents and actions. Supplements 1990;31():283-6.
1990: Johan Garssen; Henk Van Loveren; H Van der Vliet; H Bot; Frans P Nijkamp
A role for T cells in the induction of airway hyperreactivity.
Agents and actions. Supplements 1990;31():169-74.
1990: Ferdi Engels; P A J Henricks; H J van der Linde; Frans P Nijkamp
Modulation of guinea pig airway reactivity by the linoleic acid metabolite 13-hydroxy-octadecadienoic acid (13-HODE).
Agents and actions. Supplements 1990;31():113-7.
1990: Antoon J M Van Oosterhout; W B Stam; Frans P Nijkamp
Effect of lymphokines on beta-adrenoceptor stimulation of human PBMC.
Agents and actions. Supplements 1990;31():163-7.
1990: Gert Folkerts; Betty C A M van Esch; M Janssen; Frans P Nijkamp
Superoxide production by broncho-alveolar cells is diminished in parainfluenza-3 virus treated guinea pigs.
Agents and actions. Supplements 1990;31():139-42.
1989: F J Grommers; D Van de Geer; H Van der Vliet; P A J Henricks; Frans P Nijkamp
Polymorphonuclear leucocyte function: relationship between induced migration into the bovine mammary gland and in vitro cell activity.
Veterinary immunology and immunopathology 1989;23(1-2):75-83.
1989: Ferdi Engels; P A J Henricks; H van der Vliet; Frans P Nijkamp
Modulatory activity of 9-hydroxy- and 9-hydroperoxy-octadecadienoic acid towards reactive oxygen species from guinea-pig pulmonary macrophages.
European journal of biochemistry / FEBS 1989;184(1):197-203.
1989: Frans P Nijkamp; Gert Folkerts; J R Beetens; F De Clerck
Suppression of PAF-induced bronchoconstriction in the guinea-pig by oxatomide: mechanism of action.
Naunyn-Schmiedeberg's archives of pharmacology 1989;340(1):111-8.
1989: Ferdi Engels; J R Carstairs; Peter J Barnes; Frans P Nijkamp
Autoradiographic localization of changes in pulmonary beta-adrenoceptors in an animal model of atopy.
European journal of pharmacology 1989;164(1):139-46.
1989: Dicky van Heuven-Nolsen; G A Ten Have; Frans P Nijkamp
Increased reactivity to histamine in the coronary vascular system of the guinea-pig after endotoxin.
Agents and actions 1989;27(1-2):158-9.
1989: Dicky van Heuven-Nolsen; E Schoute; P D Verdouw; Dick J De Wildt; Frans P Nijkamp
In vivo beta 2-adrenoceptor hyporesponsiveness in the cardiovascular system of the pig after Bordetella pertussis.
European journal of pharmacology 1989;162(1):135-41.
1989: Gert Folkerts; Ferdi Engels; Frans P Nijkamp
Endotoxin-induced hyperreactivity of the guinea-pig isolated trachea coincides with decreased prostaglandin E2 production by the epithelial layer.
British journal of pharmacology 1989;96(2):388-94.
1989: Gert Folkerts; Ferdi Engels; Frans P Nijkamp
Respiratory airway hyperreactivity coincides with decreased epithelium-derived PGE2.
Agents and actions 1989;26(1-2):68-9.
1989: Frans P Nijkamp; P Braquet; Roger Kessels; Dicky van Heuven-Nolsen
Role of platelet activating factor in the endotoxin induced tracheal hyperreactivity to histamine in the guinea pig.
Agents and actions 1989;26(1-2):117-8.
1989: H van der Vliet; P A J Henricks; F J Grommers; D van de Geer; Frans P Nijkamp
The relationship between phagocytic activity of polymorphonuclear leukocytes and mastitis in cattle.
Agents and actions 1989;26(1-2):211-2.
1989: Betty C A M van Esch; P A J Henricks; Antoon J M Van Oosterhout; Frans P Nijkamp
Guinea pig alveolar macrophages possess beta-adrenergic receptors.
Agents and actions 1989;26(1-2):123-4.
1989: C Loesberg; M v d Stelt; G J Hooyman; E J Hensen; Frans P Nijkamp
Membrane fluidity of guinea pig lymphocytes and the dysfunction of the respiratory airway and lymphocyte beta-adrenergic systems of the guinea pig.
Life sciences 1989;45(14):1227-35.
1989: C Loesberg; M vd Stelt; G J Hooyman; E J Hensen; Frans P Nijkamp
Beta-adrenergic binding sites and membrane fluidity of guinea pig lymphocytes.
Agents and actions 1989;26(1-2):55-6.
1989: P A J Henricks; Ferdi Engels; H van der Vliet; Frans P Nijkamp
The generation of chemiluminescence by alveolar macrophages is affected by 9-hydroxy-linoleic acid.
Agents and actions 1989;26(1-2):178-9.
1989: C Loesberg; P A J Henricks; Frans P Nijkamp
Inverse relationship between superoxide anion production of guinea pig alveolar macrophages and tracheal beta-adrenergic receptor function; influence of dietary polyunsaturated fatty acids.
International journal of immunopharmacology 1989;11(2):165-71.
1989: Antoon J M Van Oosterhout; Dicky van Heuven-Nolsen; S F De Boer; J H Thijssen; Frans P Nijkamp
Endotoxin-induced reduction of beta-adrenergic binding sites on splenic lymphocytes in vivo and in vitro: its modulation by anterior hypothalamic lesions.
Life sciences 1989;44(1):57-65.
1989: M Diamant; P A J Henricks; Frans P Nijkamp; D de Wied
Beta-endorphin and related peptides suppress phorbol myristate acetate-induced respiratory burst in human polymorphonuclear leukocytes.
Life sciences 1989;45(17):1537-45.
1988: C Loesberg; Gert Folkerts; Frans P Nijkamp
Effects of dietary linoleic acid on beta-adrenergic responsiveness of the guinea pig respiratory system.
Prostaglandins, leukotrienes, and essential fatty acids 1988;34(2):127-34.
1988: P A J Henricks; Betty C A M van Esch; Antoon J M Van Oosterhout; Frans P Nijkamp
Specific and non-specific effects of beta-adrenoceptor agonists on guinea pig alveolar macrophage function.
European journal of pharmacology 1988;152(3):321-30.
1988: Antoon J M Van Oosterhout; F M Woutersen-van Nijnanten; Gert Folkerts; Frans P Nijkamp
Effects of anterior hypothalamic lesions and sham-operations on bacterial endotoxin-induced non-specific airway hyperreactivity in vivo and in vitro.
British journal of pharmacology 1988;94(3):908-16.
1988: Gert Folkerts; P A J Henricks; P J Slootweg; Frans P Nijkamp
Endotoxin-induced inflammation and injury of the guinea pig respiratory airways cause bronchial hyporeactivity.
The American review of respiratory disease 1988;137(6):1441-8.
1988: Antoon J M Van Oosterhout; F M Woutersen-Van Nijnanten; Frans P Nijkamp
Cyclosporin-A prevents endotoxin-induced beta-adrenoceptor impairment in lymphocytes.
European journal of pharmacology 1988;149(1-2):191-2.
1988: Antoon J M Van Oosterhout; Gert Folkerts; G A Ten Have; Frans P Nijkamp
Involvement of the spleen in the endotoxin-induced deterioration of the respiratory airway and lymphocyte beta-adrenergic systems of the guinea pig.
European journal of pharmacology 1988;147(3):421-9.
1988: Gert Folkerts; P A J Henricks; Frans P Nijkamp
Inflammatory reactions in the respiratory airways of the guinea pig do not necessarily induce bronchial hyperreactivity.
Agents and actions 1988;23(1-2):94-6.
1988: P A J Henricks; Ferdi Engels; H van der Vliet; Frans P Nijkamp
Oxygen metabolism and eicosanoid formation of alveolar macrophages of Haemophilus influenzae-treated guinea pigs.
Agents and actions 1988;23(1-2):97-8.
1988: Gert Folkerts; Frans P Nijkamp
Effect of arachidonic acid metabolites on intact and epithelium-denuded tracheal spirals of endotoxin-treated guinea pigs.
Agents and actions 1988;23(1-2):91-3.
1988: C Loesberg; P A J Henricks; Frans P Nijkamp
Superoxide anion production by alveolar macrophages of guinea pigs fed different diets in a model of atopy.
Agents and actions 1988;23(1-2):99-100.
1988: Dicky van Heuven-Nolsen; P D Verdouw; Dick J De Wildt; Frans P Nijkamp
Cardiovascular response to beta-adrenergic and muscarinic cholinergic receptor stimulation deteriorates in Bordetella pertussis-vaccinated pigs.
Agents and actions 1988;23(1-2):89-90.
1987: P A J Henricks; G J Binkhorst; Frans P Nijkamp
Stress diminishes infiltration and oxygen metabolism of phagocytic cells in calves.
Inflammation 1987;11(4):427-37.
1987: C Loesberg; F M Woutersen-van Nijnanten; Frans P Nijkamp
Effects of dietary poly-unsaturated fatty acids on tracheal histaminergic and cholinergic responsiveness in experimental models of bronchial hypersensitivity and hyperreactivity.
Agents and actions 1987;22(3-4):223-30.
1987: Ferdi Engels; Gert Folkerts; Dicky van Heuven-Nolsen; Frans P Nijkamp
Haemophilus influenzae-induced decreases in lung beta-adrenoceptor function and number coincide with decreases in spleen noradrenaline.
Naunyn-Schmiedeberg's archives of pharmacology 1987;336(3):274-9.
1987: P A J Henricks; Ferdi Engels; H van der Vliet; Frans P Nijkamp
Phagocytosis and metabolism of alveolar macrophages of guinea pigs treated with Haemophilus influenzae.
International journal of immunopharmacology 1987;9(7):833-9.
1987: Dicky van Heuven-Nolsen; Dick J De Wildt; Frans P Nijkamp
Cyclo-oxygenase products mediate down regulation of beta 2-adrenoceptor function in the guinea pig coronary vascular system by endotoxin.
Advances in prostaglandin, thromboxane, and leukotriene research 1987;17B():913-7.
1986: P A J Henricks; G J Binkhorst; Frans P Nijkamp
Stress influences phagocytic cell function in calves.
Agents and actions 1986;19(5-6):355-6.
1986: Antoon J M Van Oosterhout; G A Ten Have; Frans P Nijkamp
Endotoxin-induced reduction of beta-adrenoceptor number in guinea pig splenic lymphocyte membranes.
Agents and actions 1986;19(5-6):361-2.
1986: C Loesberg; Gert Folkerts; F M Woutersen-van Nijnanten; Frans P Nijkamp
Effects of dietary poly-unsaturated fatty acids on the beta-adrenergic receptor reactivity in the guinea pig respiratory system.
Agents and actions 1986;19(5-6):359-60.
1986: P A J Henricks; Betty C A M van Esch; Frans P Nijkamp
Beta-agonists can depress oxidative metabolism of alveolar macrophages.
Agents and actions 1986;19(5-6):353-4.