Yuri Nikiforov

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Nikiforov Yuri E; Steward David L; Robinson-Smith Toni M; Haugen Bryan R; Klopper Joshua P; Zhu Zhaowen; Fagin James A; Falciglia Mercedes; Weber Katherine; Nikiforova Marina N
Molecular testing for mutations in improving the fine-needle aspiration diagnosis of thyroid nodules.
Subramanian Mahesh; Pilli Tania; Bhattacharya Palash; Pacini Furio; Nikiforov Yuri E; Kanteti Prasad V; Prabhakar Bellur S
Knockdown of IG20 gene expression renders thyroid cancer cells susceptible to apoptosis.
Gandhi Manoj S; Stringer James R; Nikiforova Marina N; Medvedovic Mario; Nikiforov Yuri E
Gene position within chromosome territories correlates with their involvement in distinct rearrangement types in thyroid cancer cells.

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2009: Nikiforov Yuri E; Steward David L; Robinson-Smith Toni M; Haugen Bryan R; Klopper Joshua P; Zhu Zhaowen; Fagin James A; Falciglia Mercedes; Weber Katherine; Nikiforova Marina N
Molecular testing for mutations in improving the fine-needle aspiration diagnosis of thyroid nodules.
The Journal of clinical endocrinology and metabolism 2009;94(6):2092-8.
2009: Subramanian Mahesh; Pilli Tania; Bhattacharya Palash; Pacini Furio; Nikiforov Yuri E; Kanteti Prasad V; Prabhakar Bellur S
Knockdown of IG20 gene expression renders thyroid cancer cells susceptible to apoptosis.
The Journal of clinical endocrinology and metabolism 2009;94(4):1467-71.
2009: Gandhi Manoj S; Stringer James R; Nikiforova Marina N; Medvedovic Mario; Nikiforov Yuri E
Gene position within chromosome territories correlates with their involvement in distinct rearrangement types in thyroid cancer cells.
Genes, chromosomes & cancer 2009;48(3):222-8.
2009: Yu Jing; Nikiforova Marina N; Hodak Steven P; Yim John H; Cai Guoping; Walls Andrew; Nikiforov Yuri E; Seethala Raja R
Tumor-to-tumor Metastases to Follicular Variant of Papillary Thyroid Carcinoma: Histologic, Immunohistochemical, and Molecular Studies of Two Unusual Cases.
Endocrine pathology 2009;20(4):235-42.
2009: Chiosea Simion; Nikiforova Marina; Zuo Hui; Ogilvie Jennifer; Gandhi Manoj; Seethala Raja R; Ohori N Paul; Nikiforov Yuri
A novel complex BRAF mutation detected in a solid variant of papillary thyroid carcinoma.
Endocrine pathology 2009;20(2):122-6.
2009: Nikiforova Marina N; Chiosea Simon I; Nikiforov Yuri E
MicroRNA expression profiles in thyroid tumors.
Endocrine pathology 2009;20(2):85-91.
2008: Matrka Laura; Steward David; Falciglia Mercedes; Nikiforov Yuri
Pharmacodynamic effect of iopanoic acid on free T(3) and T(4) levels in amiodarone-induced thyrotoxicosis.
Ear, nose, & throat journal 2008;87(12):702-4.
2008: Yip Linwah; Seethala Raja R; Nikiforova Marina N; Nikiforov Yuri E; Ogilvie Jennifer B; Carty Sally E; Yim John H
Loss of heterozygosity of selected tumor suppressor genes in parathyroid carcinoma.
Surgery 2008;144(6):949-55; discussion 954-5.
2008: Yousem Samuel A; Nikiforova Marina; Nikiforov Yuri
The histopathology of BRAF-V600E-mutated lung adenocarcinoma.
The American journal of surgical pathology 2008;32(9):1317-21.
2008: Bhatki Amol M; Brewer Brad; Robinson-Smith Toni; Nikiforov Yuri; Steward David L
Adequacy of surgeon-performed ultrasound-guided thyroid fine-needle aspiration biopsy.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2008;139(1):27-31.
2008: Filie Armando C; Asa Sylvia L; Geisinger Kim R; Logani Sanjay; Merino Maria; Nikiforov Yuri E; Clark Douglas P
Utilization of ancillary studies in thyroid fine needle aspirates: a synopsis of the National Cancer Institute Thyroid Fine Needle Aspiration State of the Science Conference.
Diagnostic cytopathology 2008;36(6):438-41.
2008: Nikiforov Yuri E
Thyroid carcinoma: molecular pathways and therapeutic targets.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2008;21 Suppl 2():S37-43.
2008: Nikiforova Marina N; Tseng George C; Steward David; Diorio Donna; Nikiforov Yuri E
MicroRNA expression profiling of thyroid tumors: biological significance and diagnostic utility.
The Journal of clinical endocrinology and metabolism 2008;93(5):1600-8.
2008: Nikiforova Marina N; Nikiforov Yuri E
Molecular genetics of thyroid cancer: implications for diagnosis, treatment and prognosis.
Expert review of molecular diagnostics 2008;8(1):83-95.
2007: Volante Marco; Collini Paola; Nikiforov Yuri E; Sakamoto Atsuhiko; Kakudo Kennichi; Katoh Ryohei; Lloyd Ricardo V; LiVolsi Virginia A; Papotti Mauro; Sobrinho-Simoes Manuel; Bussolati Gianni; Rosai Juan
Poorly differentiated thyroid carcinoma: the Turin proposal for the use of uniform diagnostic criteria and an algorithmic diagnostic approach.
The American journal of surgical pathology 2007;31(8):1256-64.
2007: Ciampi Raffaele; Giordano Thomas J; Wikenheiser-Brokamp Kathryn; Koenig Ronald J; Nikiforov Yuri E
HOOK3-RET: a novel type of RET/PTC rearrangement in papillary thyroid carcinoma.
Endocrine-related cancer 2007;14(2):445-52.
2007: Ciampi Raffaele; Nikiforov Yuri E
RET/PTC rearrangements and BRAF mutations in thyroid tumorigenesis.
Endocrinology 2007;148(3):936-41.
2007: Ryder Mabel; Nikiforov Yuri E; Fagin James A
Follicular variant papillary thyroid carcinoma arising within an ovarian teratoma.
Thyroid : official journal of the American Thyroid Association 2007;17(2):179-80.
2006: Zhu Zhaowen; Ciampi Raffaele; Nikiforova Marina N; Gandhi Manoj; Nikiforov Yuri E
Prevalence of RET/PTC rearrangements in thyroid papillary carcinomas: effects of the detection methods and genetic heterogeneity.
The Journal of clinical endocrinology and metabolism 2006;91(9):3603-10.
2006: Saad Ali G; Kumar Seena; Ron Elaine; Lubin Jay H; Stanek Jerzy; Bove Kevin E; Nikiforov Yuri E
Proliferative activity of human thyroid cells in various age groups and its correlation with the risk of thyroid cancer after radiation exposure.
The Journal of clinical endocrinology and metabolism 2006;91(7):2672-7.
2006: Nikiforov Yuri E
RET/PTC Rearrangement--a link between Hashimoto's thyroiditis and thyroid cancer...or not.
The Journal of clinical endocrinology and metabolism 2006;91(6):2040-2.
2006: Giordano Thomas J; Au Amy Y M; Kuick Rork; Thomas Dafydd G; Rhodes Daniel R; Wilhelm Kenneth G; Vinco Michelle; Misek David E; Sanders Donita; Zhu Zhaowen; Ciampi Raffaele; Hanash Samir; Chinnaiyan Arul; Clifton-Bligh Roderick J; Robinson Bruce G; Nikiforov Yuri E; Koenig Ronald J
Delineation, functional validation, and bioinformatic evaluation of gene expression in thyroid follicular carcinomas with the PAX8-PPARG translocation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(7 Pt 1):1983-93.
2006: Gandhi M; Medvedovic M; Stringer J R; Nikiforov Y E
Interphase chromosome folding determines spatial proximity of genes participating in carcinogenic RET/PTC rearrangements.
Oncogene 2006;25(16):2360-6.
2006: Adeniran Adebowale J; Zhu Zhaowen; Gandhi Manoj; Steward David L; Fidler James P; Giordano Thomas J; Biddinger Paul W; Nikiforov Yuri E
Correlation between genetic alterations and microscopic features, clinical manifestations, and prognostic characteristics of thyroid papillary carcinomas.
The American journal of surgical pathology 2006;30(2):216-22.
2006: Nikiforov Yuri E
Radiation-induced thyroid cancer: what we have learned from chernobyl.
Endocrine pathology 2006;17(4):307-17.
2005: Giordano Thomas J; Kuick Rork; Thomas Dafydd G; Misek David E; Vinco Michelle; Sanders Donita; Zhu Zhaowen; Ciampi Raffaele; Roh Michael; Shedden Kerby; Gauger Paul; Doherty Gerard; Thompson Norman W; Hanash Samir; Koenig Ronald J; Nikiforov Yuri E
Molecular classification of papillary thyroid carcinoma: distinct BRAF, RAS, and RET/PTC mutation-specific gene expression profiles discovered by DNA microarray analysis.
Oncogene 2005;24(44):6646-56.
2005: Knauf Jeffrey A; Ma Xiaolan; Smith Eric P; Zhang Lei; Mitsutake Norisato; Liao Xiao-Hui; Refetoff Samuel; Nikiforov Yuri E; Fagin James A
Targeted expression of BRAFV600E in thyroid cells of transgenic mice results in papillary thyroid cancers that undergo dedifferentiation.
Cancer research 2005;65(10):4238-45.
2005: Ciampi Raffaele; Knauf Jeffrey A; Rabes Hartmut M; Fagin James A; Nikiforov Yuri E
BRAF kinase activation via chromosomal rearrangement in radiation-induced and sporadic thyroid cancer.
Cell cycle (Georgetown, Tex.) 2005;4(4):547-8.
2005: Caudill Christy M; Zhu Zhaowen; Ciampi Raffaele; Stringer James R; Nikiforov Yuri E
Dose-dependent generation of RET/PTC in human thyroid cells after in vitro exposure to gamma-radiation: a model of carcinogenic chromosomal rearrangement induced by ionizing radiation.
The Journal of clinical endocrinology and metabolism 2005;90(4):2364-9.
2005: Salvatore Giuliana; Chiappetta Gennaro; Nikiforov Yuri E; Decaussin-Petrucci Myriam; Fusco Alfredo; Carney J Aidan; Santoro Massimo
Molecular profile of hyalinizing trabecular tumours of the thyroid: high prevalence of RET/PTC rearrangements and absence of B-raf and N-ras point mutations.
European journal of cancer (Oxford, England : 1990) 2005;41(5):816-21.
2005: Nikiforova Marina N; Groen Pamela; Mutema George; Nikiforov Yuri E; Witte David
Detection of SYT-SSX rearrangements in synovial sarcomas by real-time one-step RT-PCR.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 2005;8(2):162-7.
2005: Nikiforov Yuri E
Editorial: anaplastic carcinoma of the thyroid--will aurora B light a path for treatment?
The Journal of clinical endocrinology and metabolism 2005;90(2):1243-5.
2005: Ciampi Raffaele; Knauf Jeffrey A; Kerler Roswitha; Gandhi Manoj; Zhu Zhaowen; Nikiforova Marina N; Rabes Hartmut M; Fagin James A; Nikiforov Yuri E
Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer.
The Journal of clinical investigation 2005;115(1):94-101.
2005: Ciampi Raffaele; Nikiforov Yuri E
Alterations of the BRAF gene in thyroid tumors.
Endocrine pathology 2005;16(3):163-72.
2005: Ciampi Raffaele; Zhu Zhaowen; Nikiforov Yuri E
BRAF copy number gains in thyroid tumors detected by fluorescence in situ hybridization.
Endocrine pathology 2005;16(2):99-105.
2004: Elisei Rossella; Cosci Barbara; Romei Cristina; Agate Laura; Piampiani Pamela; Miccoli Paolo; Berti Piero; Basolo Fulvio; Ugolini Clara; Ciampi Raffaele; Nikiforov Yuri; Pinchera Aldo
Identification of a novel point mutation in the RET gene (Ala883Thr), which is associated with medullary thyroid carcinoma phenotype only in homozygous condition.
The Journal of clinical endocrinology and metabolism 2004;89(11):5823-7.
2004: Salvatore Giuliana; Giannini Riccardo; Faviana Pinuccia; Caleo Alessia; Migliaccio Ilenia; Fagin James A; Nikiforov Yuri E; Troncone Giancarlo; Palombini Lucio; Basolo Fulvio; Santoro Massimo
Analysis of BRAF point mutation and RET/PTC rearrangement refines the fine-needle aspiration diagnosis of papillary thyroid carcinoma.
The Journal of clinical endocrinology and metabolism 2004;89(10):5175-80.
2004: Kim Joseph; Nikiforov Yuri E; Moulton Jonathan S; Lowy Andrew M
Multiple focal nodular hyperplasia of the liver in a 21-year-old woman.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2004;8(5):591-5.
2004: Saad Aly; Falciglia Mercedes; Steward David L; Nikiforov Yuri E
Amiodarone-induced thyrotoxicosis and thyroid cancer: clinical, immunohistochemical, and molecular genetic studies of a case and review of the literature.
Archives of pathology & laboratory medicine 2004;128(7):807-10.
2004: Vitagliano Donata; Carlomagno Francesca; Motti Maria Letizia; Viglietto Giuseppe; Nikiforov Yuri E; Nikiforova Marina N; Hershman Jerome M; Ryan Anderson J; Fusco Alfredo; Melillo Rosa Marina; Santoro Massimo
Regulation of p27Kip1 protein levels contributes to mitogenic effects of the RET/PTC kinase in thyroid carcinoma cells.
Cancer research 2004;64(11):3823-9.
2004: Nikiforova Marina N; Ciampi Raffaele; Salvatore Giuliana; Santoro Massimo; Gandhi Manoj; Knauf Jeffrey A; Thomas Gerry A; Jeremiah Stephen; Bogdanova Tatyana I; Tronko Mykola D; Fagin James A; Nikiforov Yuri E
Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomas.
Cancer letters 2004;209(1):1-6.
2004: Kimura Edna T; Vanvooren Vanessa; van Sande Jacqueline; Nikiforov Yuri E; Fagin James A
Autonomously functioning thyroid nodules are not associated with BRAF mutations.
Clinical endocrinology 2004;60(3):394-6.
2004: Nikiforov Yuri E
The molecular pathways induced by radiation and leading to thyroid carcinogenesis.
Cancer treatment and research 2004;122():191-206.
2004: Nikiforov Yuri E
Genetic alterations involved in the transition from well-differentiated to poorly differentiated and anaplastic thyroid carcinomas.
Endocrine pathology 2004;15(4):319-27.
2003: Adeniran Adebowale; Dimashkieh Haytham; Nikiforov Yuri
Schistosomiasis of the cervix.
Archives of pathology & laboratory medicine 2003;127(12):1637-8.
2003: Nikiforova Marina N; Kimura Edna T; Gandhi Manoj; Biddinger Paul W; Knauf Jeffrey A; Basolo Fulvio; Zhu Zhaowen; Giannini Riccardo; Salvatore Giuliana; Fusco Alfredo; Santoro Massimo; Fagin James A; Nikiforov Yuri E
BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas.
The Journal of clinical endocrinology and metabolism 2003;88(11):5399-404.
2003: Zhu Zhaowen; Gandhi Manoj; Nikiforova Marina N; Fischer Andrew H; Nikiforov Yuri E
Molecular profile and clinical-pathologic features of the follicular variant of papillary thyroid carcinoma. An unusually high prevalence of ras mutations.
American journal of clinical pathology 2003;120(1):71-7.
2003: Nikiforova Marina N; Lynch Roy A; Biddinger Paul W; Alexander Erik K; Dorn Gerald W; Tallini Giovanni; Kroll Todd G; Nikiforov Yuri E
RAS point mutations and PAX8-PPAR gamma rearrangement in thyroid tumors: evidence for distinct molecular pathways in thyroid follicular carcinoma.
The Journal of clinical endocrinology and metabolism 2003;88(5):2318-26.
2003: Kimura Edna T; Nikiforova Marina N; Zhu Zhaowen; Knauf Jeffrey A; Nikiforov Yuri E; Fagin James A
High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma.
Cancer research 2003;63(7):1454-7.
2002: Nikiforova Marina N; Biddinger Paul W; Caudill Christy M; Kroll Todd G; Nikiforov Yuri E
PAX8-PPARgamma rearrangement in thyroid tumors: RT-PCR and immunohistochemical analyses.
The American journal of surgical pathology 2002;26(8):1016-23.
2002: Knauf Jeffrey A; Ward Laura S; Nikiforov Yuri E; Nikiforova Marina; Puxeddu Efisio; Medvedovic Mario; Liron Tamar; Mochly-Rosen Daria; Fagin James A
Isozyme-specific abnormalities of PKC in thyroid cancer: evidence for post-transcriptional changes in PKC epsilon.
The Journal of clinical endocrinology and metabolism 2002;87(5):2150-9.
2002: Basolo Fulvio; Giannini Riccardo; Toniolo Antonio; Casalone Rosario; Nikiforova Marina; Pacini Furio; Elisei Rossella; Miccoli Paolo; Berti Piero; Faviana Pinuccia; Fiore Lisa; Monaco Carmen; Pierantoni Giovanna Maria; Fedele Monica; Nikiforov Yuri E; Santoro Massimo; Fusco Alfredo
Establishment of a non-tumorigenic papillary thyroid cell line (FB-2) carrying the RET/PTC1 rearrangement.
International journal of cancer. Journal international du cancer 2002;97(5):608-14.
2002: Nikiforova Marina N; Caudill Christy M; Biddinger Paul; Nikiforov Yuri E
Prevalence of RET/PTC rearrangements in Hashimoto's thyroiditis and papillary thyroid carcinomas.
International journal of surgical pathology 2002;10(1):15-22.
2002: Nikiforov Yuri E
RET/PTC rearrangement in thyroid tumors.
Endocrine pathology 2002;13(1):3-16.
2001: Nikiforov Y E; Erickson L A; Nikiforova M N; Caudill C M; Lloyd R V
Solid variant of papillary thyroid carcinoma: incidence, clinical-pathologic characteristics, molecular analysis, and biologic behavior.
The American journal of surgical pathology 2001;25(12):1478-84.
2001: Radivoyevitch T; Sachs R K; Nikiforov Y E; Nikiforova M N; Little M P
On target cell numbers in radiation-induced H4-RET mediated papillary thyroid cancer.
Radiation and environmental biophysics 2001;40(3):191-7.
2001: Nikiforov Y E
Spatial positioning of RET and H4 following radiation exposure leads to tumor development.
TheScientificWorldJournal 2001;1():186-7.
2001: Mochly-Rosen D; Fagin J A; Knauf J A; Nikiforov Y; Liron T; Schechtman D
Spontaneous occurrence of an inhibitor of protein kinase C localization in a thyroid cancer cell line: role in thyroid tumorigenesis.
Advances in enzyme regulation 2001;41():87-97.
2000: Nikiforova M N; Stringer J R; Blough R; Medvedovic M; Fagin J A; Nikiforov Y E
Proximity of chromosomal loci that participate in radiation-induced rearrangements in human cells.
Science (New York, N.Y.) 2000;290(5489):138-41.
2000: Bejarano P A; Nikiforov Y E; Swenson E S; Biddinger P W
Thyroid transcription factor-1, thyroglobulin, cytokeratin 7, and cytokeratin 20 in thyroid neoplasms.
Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry 2000;8(3):189-94.
2000: Patel A; Fenton C; Ramirez R; Dinauer C A; Tuttle R M; Nikiforov Y E; Gary F L
Tyrosine kinase expression is increased in papillary thyroid carcinoma of children and young adults.
Frontiers in bioscience : a journal and virtual library 2000;5():A1-9.
1999: Nikiforov Y E; Koshoffer A; Nikiforova M; Stringer J; Fagin J A
Chromosomal breakpoint positions suggest a direct role for radiation in inducing illegitimate recombination between the ELE1 and RET genes in radiation-induced thyroid carcinomas.
Oncogene 1999;18(46):6330-4.
1999: Nikiforova M N; Nikiforov Y E; Biddinger P; Gnepp D R; Grosembacher L A; Wajchenberg B L; Fagin J A; Cohen R M
Frequent loss of heterozygosity at chromosome 3p14.2-3p21 in human pancreatic islet cell tumours.
Clinical endocrinology 1999;51(1):27-33.
1999: Evans H A; Shaughnessy E A; Nikiforov Y E
Infiltrating ductal carcinoma of the breast with osseous metaplasia: imaging findings with pathologic correlation.
AJR. American journal of roentgenology 1999;172(5):1420-2.
1999: Nikiforov Y E; Gnepp D R
Pathomorphology of thyroid gland lesions associated with radiation exposure: the Chernobyl experience and review of the literature.
Advances in anatomic pathology 1999;6(2):78-91.
1998: Nikiforov Y E; Nikiforova M; Fagin J A
Prevalence of minisatellite and microsatellite instability in radiation-induced post-Chernobyl pediatric thyroid carcinomas.
Oncogene 1998;17(15):1983-8.
1998: Motomura T; Nikiforov Y E; Namba H; Ashizawa K; Nagataki S; Yamashita S; Fagin J A
ret rearrangements in Japanese pediatric and adult papillary thyroid cancers.
Thyroid : official journal of the American Thyroid Association 1998;8(6):485-9.
1998: Wang J; Niu W; Witte D P; Chernausek S D; Nikiforov Y E; Clemens T L; Sharifi B; Strauch A R; Fagin J A
Overexpression of insulin-like growth factor-binding protein-4 (IGFBP-4) in smooth muscle cells of transgenic mice through a smooth muscle alpha-actin-IGFBP-4 fusion gene induces smooth muscle hypoplasia.
Endocrinology 1998;139(5):2605-14.
1997: Wang J; Niu W; Nikiforov Y; Naito S; Chernausek S; Witte D; LeRoith D; Strauch A; Fagin J A
Targeted overexpression of IGF-I evokes distinct patterns of organ remodeling in smooth muscle cell tissue beds of transgenic mice.
The Journal of clinical investigation 1997;100(6):1425-39.
1997: Nikiforov Y E; Rowland J M; Bove K E; Monforte-Munoz H; Fagin J A
Distinct pattern of ret oncogene rearrangements in morphological variants of radiation-induced and sporadic thyroid papillary carcinomas in children.
Cancer research 1997;57(9):1690-4.
1997: Nikiforov Y E; Fagin J A
Risk factors for thyroid cancer.
Trends in endocrinology and metabolism: TEM 1997;8(1):20-5.
1996: Nikiforov Y E; Nikiforova M N; Gnepp D R; Fagin J A
Prevalence of mutations of ras and p53 in benign and malignant thyroid tumors from children exposed to radiation after the Chernobyl nuclear accident.
Oncogene 1996;13(4):687-93.
1996: Nikiforov Y; Gnepp D R; Fagin J A
Thyroid lesions in children and adolescents after the Chernobyl disaster: implications for the study of radiation tumorigenesis.
The Journal of clinical endocrinology and metabolism 1996;81(1):9-14.
1995: Nikiforov Y E; Heffess C S; Korzenko A V; Fagin J A; Gnepp D R
Characteristics of follicular tumors and nonneoplastic thyroid lesions in children and adolescents exposed to radiation as a result of the Chernobyl disaster.
Cancer 1995;76(5):900-9.
1994: Nikiforov Y; Gnepp D R
Pediatric thyroid cancer after the Chernobyl disaster. Pathomorphologic study of 84 cases (1991-1992) from the Republic of Belarus.
Cancer 1994;74(2):748-66.

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Yuri Nikiforov

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