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Lennard Niles

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Lennard P Niles; Yi Pan; Sean Kang; Ayush Lacoul
Melatonin induces histone hyperacetylation in the rat brain.
Lennard P Niles; Na Hyea Kang; Derek K Lobb; Kristen J Armstrong
Resistin expression in human granulosa cells.
Lennard P Niles; Sarra Bahna; Na Hyea Kang; Arani Sathiyapalan; Yi Pan
Valproic acid up-regulates melatonin MT1 and MT2 receptors and neurotrophic factors CDNF and MANF in the rat brain.

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All Publications

2013: Lennard P Niles; Yi Pan; Sean Kang; Ayush Lacoul
Melatonin induces histone hyperacetylation in the rat brain.
Neuroscience letters 2013;541():49-53.
2012: Lennard P Niles; Na Hyea Kang; Derek K Lobb; Kristen J Armstrong
Resistin expression in human granulosa cells.
Endocrine 2012;42(3):742-5.
2012: Lennard P Niles; Sarra Bahna; Na Hyea Kang; Arani Sathiyapalan; Yi Pan
Valproic acid up-regulates melatonin MT1 and MT2 receptors and neurotrophic factors CDNF and MANF in the rat brain.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2012;15(9):1343-50.
2012: Angie Yeung; Raphael Ahn; Sarra Bahna; Rishi K Bhargava; Na Hyea Kang; Ayush Lacoul; Lennard P Niles
HDAC inhibitor M344 suppresses MCF-7 breast cancer cell proliferation.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2012;66(3):232-6.
2008: Rohita Sharma; Thomas Ottenhof; Paulina A Rzeczkowska; Lennard P Niles
Epigenetic targets for melatonin: induction of histone H3 hyperacetylation and gene expression in C17.2 neural stem cells.
Journal of pineal research 2008;45(3):277-84.
2008: Bora Kim; Lyda M Rincón Castro; Sana Jawed; Lennard P Niles
Clinically relevant concentrations of valproic acid modulate melatonin MT(1) receptor, HDAC and MeCP2 mRNA expression in C6 glioma cells.
European journal of pharmacology 2008;589(1-3):45-8.
2007: Rohita Sharma; Catherine R McMillan; Lennard P Niles
Neural stem cell transplantation and melatonin treatment in a 6-hydroxydopamine model of Parkinson's disease.
Journal of pineal research 2007;43(3):245-54.
2007: Catherine R McMillan; Rohita Sharma; Tom Ottenhof; Lennard P Niles
Modulation of tyrosine hydroxylase expression by melatonin in human SH-SY5Y neuroblastoma cells.
Neuroscience letters 2007;419(3):202-6.
2007: Sana Jawed; Bora Kim; Thomas Ottenhof; Gregory Brown; Eva S Werstiuk; Lennard P Niles
Human melatonin MT1 receptor induction by valproic acid and its effects in combination with melatonin on MCF-7 breast cancer cell proliferation.
European journal of pharmacology 2007;560(1):17-22.
2006: Rohita Sharma; Catherine R McMillan; Catherine C Tenn; Lennard P Niles
Physiological neuroprotection by melatonin in a 6-hydroxydopamine model of Parkinson's disease.
Brain research 2006;1068(1):230-6.
2005: Lyda M Rincón Castro; Michel Gallant; Lennard P Niles
Novel targets for valproic acid: up-regulation of melatonin receptors and neurotrophic factors in C6 glioma cells.
Journal of neurochemistry 2005;95(5):1227-36.
2004: Lennard P Niles; Kristen J Armstrong; Lyda M Rincón Castro; Chung V Dao; Rohita Sharma; Catherine R McMillan; Laurie C Doering; David L Kirkham
Neural stem cells express melatonin receptors and neurotrophic factors: colocalization of the MT1 receptor with neuronal and glial markers.
BMC neuroscience 2004;5():41.
2002: Kristen J Armstrong; Lennard P Niles
Induction of GDNF mRNA expression by melatonin in rat C6 glioma cells.
Neuroreport 2002;13(4):473-5.
1999: Lennard P Niles; J Wang; L Shen; Derek K Lobb; Edward V Younglai
Melatonin receptor mRNA expression in human granulosa cells.
Molecular and cellular endocrinology 1999;156(1-2):107-10.
1999: Lennard P Niles; J Wang
Diazepam inhibits forskolin-stimulated adenylyl cyclase activity in human tumour cells.
Pharmacology & toxicology 1999;85(4):153-6.
1997: Catherine C Tenn; Lennard P Niles
Mechanisms underlying the antidopaminergic effect of clonazepam and melatonin in striatum.
Neuropharmacology 1997;36(11-12):1659-63.
1997: Catherine C Tenn; Lennard P Niles
Sensitization of G protein-coupled benzodiazepine receptors in the striatum of 6-hydroxydopamine-lesioned rats.
Journal of neurochemistry 1997;69(5):1920-6.
1997: Lennard P Niles; L J Smith; Catherine C Tenn
Modulation of c-fos expression in the rat striatum by diazepam.
Neuroscience letters 1997;236(1):5-8.
1997: J M Neu; Lennard P Niles
A marked diurnal rhythm of melatonin ML1A receptor mRNA expression in the suprachiasmatic nucleus.
Brain research. Molecular brain research 1997;49(1-2):303-6.
1997: Catherine C Tenn; Lennard P Niles
The antidopaminergic action of S-20098 is mediated by benzodiazepine/GABA(A) receptors in the striatum.
Brain research 1997;756(1-2):293-6.
1996: Catherine C Tenn; J M Neu; Lennard P Niles
PK 11195 blockade of benzodiazepine-induced inhibition of forskolin-stimulated adenylate cyclase activity in the striatum.
British journal of pharmacology 1996;119(2):223-8.
1996: C E Crocker; Lennard P Niles
Benzodiazepine-induced inhibition of human malignant melanoma (M-6) cell growth.
Anticancer research 1996;16(3A):1259-63.
1995: Catherine C Tenn; Lennard P Niles
Central-type benzodiazepine receptors mediate the antidopaminergic effect of clonazepam and melatonin in 6-hydroxydopamine lesioned rats: involvement of a GABAergic mechanism.
The Journal of pharmacology and experimental therapeutics 1995;274(1):84-9.
1995: S M Yie; Lennard P Niles; Edward V Younglai
Melatonin receptors on human granulosa cell membranes.
The Journal of clinical endocrinology and metabolism 1995;80(5):1747-9.
1994: Lennard P Niles; C Harjivan; A Nanji
Heparin inhibits melatonin binding and signal transduction in chick brain.
Biological signals 1994;3(1):26-33.
1993: Catherine C Tenn; Lennard P Niles
Physiological regulation of melatonin receptors in rat suprachiasmatic nuclei: diurnal rhythmicity and effects of stress.
Molecular and cellular endocrinology 1993;98(1):43-8.
1993: S W Ying; Lennard P Niles; C Crocker
Human malignant melanoma cells express high-affinity receptors for melatonin: antiproliferative effects of melatonin and 6-chloromelatonin.
European journal of pharmacology 1993;246(2):89-96.
1992: S W Ying; Lennard P Niles; D Pickering; M Ye
Involvement of multiple sulfhydryl groups in melatonin signal transduction in chick brain.
Molecular and cellular endocrinology 1992;85(1-2):53-63.
1992: D S Pickering; Lennard P Niles
Expression of nanomolar-affinity binding sites for melatonin in Syrian hamster RPMI 1846 melanoma cells.
Cellular signalling 1992;4(2):201-7.
1991: Lennard P Niles; M Ye; D S Pickering; S W Ying
Pertussis toxin blocks melatonin-induced inhibition of forskolin-stimulated adenylate cyclase activity in the chick brain.
Biochemical and biophysical research communications 1991;178(2):786-92.
1991: S W Ying; Lennard P Niles
3-[(3-cholamidopropyl)dimethylammonio]-1-propane sulfonate-solubilized binding sites for 2-[125I]iodomelatonin in chick brain retain sensitivity to guanine nucleotides.
Journal of neurochemistry 1991;56(2):580-6.
1991: Catherine C Tenn; Lennard P Niles
A novel and sensitive radioreceptor assay for serum melatonin levels.
Life sciences 1991;49(25):1895-900.
1991: Lennard P Niles
Melatonin interaction with the benzodiazepine-GABA receptor complex in the CNS.
Advances in experimental medicine and biology 1991;294():267-77.
1990: Lennard P Niles; F S Hashemi
Pharmacological inhibition of forskolin-stimulated adenylate cyclase activity in rat brain by melatonin, its analogs, and diazepam.
Biochemical pharmacology 1990;40(12):2701-5.
1990: Lennard P Niles; F Hashemi
Picomolar-affinity binding and inhibition of adenylate cyclase activity by melatonin in Syrian hamster hypothalamus.
Cellular and molecular neurobiology 1990;10(4):553-8.
1990: Lennard P Niles
GTP modulates [125I]iodomelatonin binding to a picomolar-affinity site in the Syrian hamster hypothalamus.
European journal of pharmacology 1990;189(1):95-8.
1990: Lennard P Niles; C H Peace
Allosteric modulation of t-[35S]butylbicyclophosphorothionate binding in rat brain by melatonin.
Brain research bulletin 1990;24(4):635-8.
1990: D S Pickering; Lennard P Niles
Pharmacological characterization of melatonin binding sites in Syrian hamster hypothalamus.
European journal of pharmacology 1990;175(1):71-7.
1989: P Kostka; S N Sipos; Chiu-Yin Kwan; Lennard P Niles; Edwin E Daniel
Identification and characterization of presynaptic and postsynaptic beta adrenoreceptors in the longitudinal smooth muscle/myenteric plexus of dog ileum.
The Journal of pharmacology and experimental therapeutics 1989;251(1):305-10.
1989: D S Pickering; Lennard P Niles
2-[125I]iodomelatonin binding sites in hamster and chick exhibit differential sensitivity to prazosin.
The Journal of pharmacy and pharmacology 1989;41(5):356-7.
1988: F M Coloma; Lennard P Niles
Melatonin enhancement of [3H]-gamma-aminobutyric acid and [3H]muscimol binding in rat brain.
Biochemical pharmacology 1988;37(7):1271-4.
1988: Lennard P Niles; O M Pulido; D S Pickering
Age-related changes in GABA and benzodiazepine receptor binding in rat brain are influenced by sampling time.
Progress in neuro-psychopharmacology & biological psychiatry 1988;12(2-3):337-44.
1987: Lennard P Niles; D S Pickering; B G Sayer
HPLC-purified 2-[125I]iodomelatonin labels multiple binding sites in hamster brain.
Biochemical and biophysical research communications 1987;147(3):949-56.
1987: Lennard P Niles; D S Pickering; M A Arciszewski
Effects of chronic melatonin administration on GABA and diazepam binding in rat brain.
Journal of neural transmission 1987;70(1-2):117-24.
1984: F M Coloma; Lennard P Niles
In vitro effects of melatonin on [3H]muscimol binding in rat brain.
Progress in neuro-psychopharmacology & biological psychiatry 1984;8(4-6):669-72.