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Stephen Nimer

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Ly P Vu; Luisa Luciani; Stephen D Nimer
Histone-modifying enzymes: their role in the pathogenesis of acute leukemia and their therapeutic potential.
Yan Liu; Hao Yu; Stephen D Nimer
PI3K-Akt pathway regulates polycomb group protein and stem cell maintenance.
Elena Bazzoli; Cameron Brennan; Lisa M DeAngelis; Elena I Fomchenko; Eric C Holland; Jason Huse; Stephen D Nimer; Moritz C Oberstadt; Fabiana Perna; Teodoro Pulvirenti; Nikolaus Schultz; Viviane Tabar; Francesca Voza; Boyoung Wee; Massimo Squatrito
MEF promotes stemness in the pathogenesis of gliomas.

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All Publications

2013: Ly P Vu; Luisa Luciani; Stephen D Nimer
Histone-modifying enzymes: their role in the pathogenesis of acute leukemia and their therapeutic potential.
International journal of hematology 2013;97(2):198-209.
2013: Yan Liu; Hao Yu; Stephen D Nimer
PI3K-Akt pathway regulates polycomb group protein and stem cell maintenance.
Cell cycle (Georgetown, Tex.) 2013;12(2):199-200.
2012: Elena Bazzoli; Cameron Brennan; Lisa M DeAngelis; Elena I Fomchenko; Eric C Holland; Jason Huse; Stephen D Nimer; Moritz C Oberstadt; Fabiana Perna; Teodoro Pulvirenti; Nikolaus Schultz; Viviane Tabar; Francesca Voza; Boyoung Wee; Massimo Squatrito
MEF promotes stemness in the pathogenesis of gliomas.
Cell stem cell 2012;11(6):836-44.
2012: Yan Liu; Ingo K Mellinghoff; Silvia Menendez; Yasuhiko Miyata; Pier Paolo Pandolfi; Neal Rosen; Goro Sashida; Qing-Bai She; Youyang Yang; Hao Yu; Xinyang Zhao; Zhenbang Chen; Anthony Deblasio; Silvana Di giandomenico; Shannon E Elf; Michael Harr; Cyrus V Hedvat; Gang Huang; Hui-Kuan Lin; Fan Liu; Stephen D Nimer
Akt phosphorylates the transcriptional repressor bmi1 to block its effects on the tumor-suppressing ink4a-arf locus.
Science signaling 2012;5(247):ra77.
2012: Haiming Xu; Brigitte Schlegelberger; Peter D Aplan; Narae Bae; Tony R Deblasio; Gudrun Göhring; Silvia Menendez; Stephen D Nimer
Loss of p53 accelerates the complications of myelodysplastic syndrome in a NUP98-HOXD13-driven mouse model.
Blood 2012;120(15):3089-97.
2012: Priya Koppikar; Laura Leung; Omar Abdel-Wahab; Mazhar Adli; Bradley E Bernstein; Neha Bhagwat; Gabriela Chiosis; Benjamin L Ebert; Zeev Estrov; Aviva Goel; Mithat Gonen; Todd Hricik; Outi Kilpivaara; Fan Liu; Taghi Manshouri; Sachie Marubayashi; Ann Mullally; Stephen D Nimer; Lindsay M Saunders; Srdan Verstovsek; Abby Weinstein; Ross L Levine
Heterodimeric JAK-STAT activation as a mechanism of persistence to JAK2 inhibitor therapy.
Nature 2012;489(7414):155-9.
2012: Megan A Hatlen; Lan Wang; Stephen D Nimer
AML1-ETO driven acute leukemia: insights into pathogenesis and potential therapeutic approaches.
Frontiers of medicine 2012;6(3):248-62.
2012: Virginia M Klimek; Sean M Devlin; Emily K Dolezal; Alejandro Romero; Karen Stein; Michael T Tees; Stephen D Nimer
Efficacy of hypomethylating agents in therapy-related myelodysplastic syndromes.
Leukemia research 2012;36(9):1093-7.
2012: Takashi Asai; Narae Bae; Anthony Deblasio; Silvana Di giandomenico; Yan Liu; Silvia Menendez; Delphine Ndiaye-Lobry; Boris Reva; Rachel Wevrick; Yevgeniy Antipin; Stephen D Nimer
Necdin, a p53 target gene, regulates the quiescence and response to genotoxic stress of hematopoietic stem/progenitor cells.
Blood 2012;120(8):1601-12.
2012: Omar Abdel-Wahab; Mazhar Adli; Ioannis Aifantis; Bradley E Bernstein; Martin Carroll; Young Rock Chung; Jie Gao; Todd Hricik; Jacob D Jaffe; Richard Koche; Lindsay M LaFave; Ari Melnick; Stephen D Nimer; Suveg Pandey; Christopher Y Park; Jay P Patel; Fabiana Perna; Alan H Shih; Jordan E Taylor; Xinyang Zhao; Ross L Levine
ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression.
Cancer cell 2012;22(2):180-93.
2012: Heather J Landau; Samuel C McNeely; Jayasree S Nair; Stephen D Nimer; Takashi Asai; Raymond L Comenzo; Hillel Friedman; Suresh C Jhanwar; Gary K Schwartz
The checkpoint kinase inhibitor AZD7762 potentiates chemotherapy-induced apoptosis of p53-mutated multiple myeloma cells.
Molecular cancer therapeutics 2012;11(8):1781-8.
2012: Wei-Jong Shia; Ming Yan; John R Yates; Yukiko Komeno; Miao-Chia Lo; Shinobu Matsuura; Stephen D Nimer; Akiko J Okumura; Ali Sarkeshik; Xinyang Zhao; Dong-Er Zhang
PRMT1 interacts with AML1-ETO to promote its transcriptional activation and progenitor cell proliferative potential.
Blood 2012;119(21):4953-62.
2012: Virginia M Klimek; Larry Smith; Gerald Soff; Emily K Dolezal; Stephen D Nimer
Phase I trial of sodium salicylate in patients with myelodysplastic syndromes and acute myelogenous leukemia.
Leukemia research 2012;36(5):570-4.
2012: Craig Moskowitz; Stephen D Nimer; Ariela Noy; Lia Palomba; Miguel-Angel Perales; Carol Portlock; Heiko Schoder; David J Straus; John Gerecitano; Paul A Hamlin; Steven Horwitz; Jocelyn C Maragulia; Matt J Matasar; Alison J Moskowitz; Andrew D Zelenetz; Joachim Yahalom
Normalization of pre-ASCT, FDG-PET imaging with second-line, non-cross-resistant, chemotherapy programs improves event-free survival in patients with Hodgkin lymphoma.
Blood 2012;119(7):1665-70.
2012: Heather Landau; Nikoletta Lendvai; Alex Lesokhin; Stephen D Nimer; Neeta Pandit-Taskar; Elyn Riedel; Philip Schulman; P Drullinsky; Hani Hassoun; Elizabeth Hoover; Suresh Jhanwar; Christina Bello; Adam Cohen; Raymond Comenzo
Bortezomib, liposomal doxorubicin and dexamethasone followed by thalidomide and dexamethasone is an effective treatment for patients with newly diagnosed multiple myeloma with Internatinal Staging System stage II or III, or extramedullary disease.
Leukemia & lymphoma 2012;53(2):275-81.
2011: Kamalika Moulick; Len Neckers; Stephen D Nimer; Fabiana Perna; Nagavarakishore Pillarsetty; Anna Rodina; Peter Smith-Jones; Tony Taldone; Ly P Vu; Danuta Zatorska; Xinyang Zhao; Hongliang Zong; Hediye Erdjument-Bromage; Erica M Gomes DaGama; Steven S Gross; Monica L Guzman; Katerina Hatzi; Thomas Ku; Steven M Larson; Ross Levine; Jason S Lewis; Ari Melnick; James H Ahn; Mary Alpaugh; Kristin Beebe; Eloisi Caldas Lopes; Leandro Cerchietti; Gabriela Chiosis
Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90.
Nature chemical biology 2011;7(11):818-26.
2011: Ruben Hoya-Arias; Fabiana Perna; Mark Tomishima; Francesca Voza; Stephen D Nimer
L3MBTL1 deficiency directs the differentiation of human embryonic stem cells toward trophectoderm.
Stem cells and development 2011;20(11):1889-900.
2011: Takashi Asai; Narae Bae; Yan Liu; Stephen D Nimer
The p53 tumor suppressor protein regulates hematopoietic stem cell fate.
Journal of cellular physiology 2011;226(9):2215-21.
2011: Lan Wang; Haiming Xu; Hao Xu; J Zhang; Xinyang Zhao; Fabiana Perna; Robert G Roeder; Xiao-Jian Sun; Francesca Voza; Ly Vu; Takashi Asai; Philip A Cole; Tony DeBlasio; Alexander Gural; Megan A Hatlen; Gang Huang; Yanwen Jiang; Fan Liu; Ari Melnick; Silvia Menendez; Stephen D Nimer
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation.
Science (New York, N.Y.) 2011;333(6043):765-9.
2011: Goro Sashida; Xinyang Zhao; Takashi Asai; Narae Bae; Elena Bazzoli; Silvana Di giandomenico; Nadia Gurvich; Gang Huang; Yan Liu; Silvia Menendez; Stephen D Nimer
The mef/elf4 transcription factor fine tunes the DNA damage response.
Cancer research 2011;71(14):4857-65.
2011: Kelly Moran-Crusio; Delphine Ndiaye-Lobry; Stephen D Nimer; Suveg Pandey; Jay Patel; Fabiana Perna; Linsey Reavie; Alan Shih; Chunxiao Song; Aparna Vasanthakumar; Jiri Zavadil; Xinyang Zhao; Omar Abdel-Wahab; Ioannis Aifantis; Miloslav Beran; Qing Dai; Maria E Figueroa; Lucy A Godley; Chuan He; Sherif Ibrahim; Camille Lobry; Jozef Madzo; Ari Melnick; Ross L Levine
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.
Cancer cell 2011;20(1):11-24.
2011: Fan Liu; Xinyang Zhao; Fabiana Perna; Lan Wang; Priya Koppikar; Omar Abdel-Wahab; Michael W Harr; Ross L Levine; Hao Xu; Ayalew Tefferi; Anthony Deblasio; Megan Hatlen; Silvia Menendez; Stephen D Nimer
JAK2V617F-mediated phosphorylation of PRMT5 downregulates its methyltransferase activity and promotes myeloproliferation.
Cancer cell 2011;19(2):283-94.
2011: Fabiana Perna; Omar Abdel-Wahab; Ross L Levine; Suresh C Jhanwar; Kazunori Imada; Stephen D Nimer
ETV6-ABL1-positive "chronic myeloid leukemia": clinical and molecular response to tyrosine kinase inhibition.
Haematologica 2011;96(2):342-3.
2011: Peter L Greenberg; Eyal Attar; John M Bennett; Clara D Bloomfield; Carlos M De Castro; H Joachim Deeg; James M Foran; Karin Gaensler; Guillermo Garcia-Manero; Steven D Gore; David Head; Rami Komrokji; Lori J Maness; Michael Millenson; Stephen D Nimer; Margaret R O'Donnell; Mark A Schroeder; Paul J Shami; Richard M Stone; James Thompson; Peter Westervelt
NCCN Clinical Practice Guidelines in Oncology: myelodysplastic syndromes.
Journal of the National Comprehensive Cancer Network : JNCCN 2011;9(1):30-56.
2011: Stephen D Nimer
An update on the molecular pathogenesis of myelodysplastic syndromes.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2011;17(1 Suppl):S11-4.
2010: Nadia Gurvich; Fabiana Perna; Andrea Farina; Francesca Voza; Silvia Menendez; Jerard Hurwitz; Stephen D Nimer
L3MBTL1 polycomb protein, a candidate tumor suppressor in del(20q12) myeloid disorders, is essential for genome stability.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(52):22552-7.
2010: Fabiana Perna; Nadia Gurvich; Ruben Hoya-Arias; Omar Abdel-Wahab; Ross Levine; Takashi Asai; Francesca Voza; Silvia Menendez; Lan Wang; Fan Liu; Xinyang Zhao; Stephen D Nimer
Depletion of L3MBTL1 promotes the erythroid differentiation of human hematopoietic progenitor cells: possible role in 20q- polycythemia vera.
Blood 2010;116(15):2812-21.
2010: Thomas Fischer; Richard M Stone; Daniel J DeAngelo; Ilene Galinsky; Elihu Estey; Carlo Lanza; Edward Fox; Gerhard Ehninger; Eric J Feldman; Gary J Schiller; Virginia Klimek; Stephen D Nimer; D Gary Gilliland; Catherine Dutreix; Alice Huntsman-Labed; Jodi Virkus; Francis J Giles
Phase IIB trial of oral Midostaurin (PKC412), the FMS-like tyrosine kinase 3 receptor (FLT3) and multi-targeted kinase inhibitor, in patients with acute myeloid leukemia and high-risk myelodysplastic syndrome with either wild-type or mutated FLT3.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(28):4339-45.
2010: S Mathew; N Adel; Robert D. Rice; Katherine S Panageas; E T Duck; Raymond Comenzo; Tarun Kewalramani; Stephen D Nimer
Retrospective comparison of the effects of filgrastim and pegfilgrastim on the pace of engraftment in auto-SCT patients.
Bone marrow transplantation 2010;45(10):1522-7.
2010: Goro Sashida; Elena Bazzoli; Silvia Menendez; Yan Liu; Stephen D Nimer
The oncogenic role of the ETS transcription factors MEF and ERG.
Cell cycle (Georgetown, Tex.) 2010;9(17):3457-9.
2010: Craig Moskowitz; Joachim Yahalom; Andrew D Zelenetz; Zhigang Zhang; Daniel A Filippa; Julie T Feldstein; Tarun Kewalramani; Alison J Moskowitz; Robert D. Rice; Jocelyn Maragulia; Jill Vanak; Tanya M Trippett; Paul A Hamlin; Steven Horowitz; Ariela Noy; Owen A O'Connor; Carol S Portlock; David J Straus; Stephen D Nimer
High-dose chemo-radiotherapy for relapsed or refractory Hodgkin lymphoma and the significance of pre-transplant functional imaging.
British journal of haematology 2010;148(6):890-7.
2010: Yasuhiko Miyata; Yan Liu; Vladimir Jankovic; Goro Sashida; Jennifer May Lee; Jae-Hung Shieh; Tomoki Naoe; Malcolm A S Moore; Stephen D Nimer
Cyclin C regulates human hematopoietic stem/progenitor cell quiescence.
Stem cells (Dayton, Ohio) 2010;28(2):308-17.
2010: Yan Liu; Takashi Asai; Stephen D Nimer
Myelodysplasia: battle in the bone marrow.
Nature medicine 2010;16(1):30-2.
2009: Peter L Greenberg; Cynthia K Rigsby; Richard M Stone; H Joachim Deeg; Steven D Gore; Michael M Millenson; Stephen D Nimer; Margaret R O'Donnell; Paul J Shami; Rashmi Kumar
NCCN Task Force: Transfusion and iron overload in patients with myelodysplastic syndromes.
Journal of the National Comprehensive Cancer Network : JNCCN 2009;7 Suppl 9():S1-16.
2009: Yan Liu; Ruben Hoya-Arias; Stephen D Nimer
The role of p53 in limiting somatic cell reprogramming.
Cell research 2009;19(11):1227-8.
2009: Yan Liu; Shannon E Elf; Takashi Asai; Yasuhiko Miyata; Yuhui Liu; Goro Sashida; Gang Huang; Silvana Di giandomenico; Andrew Koff; Stephen D Nimer
The p53 tumor suppressor protein is a critical regulator of hematopoietic stem cell behavior.
Cell cycle (Georgetown, Tex.) 2009;8(19):3120-4.
2009: Lan Wang; Gang Huang; xinyang zhao; Megan A Hatlen; Ly Vu; Fan Liu; Stephen D Nimer
Post-translational modifications of Runx1 regulate its activity in the cell.
Blood cells, molecules & diseases 2009;43(1):30-4.
2009: Goro Sashida; Yan Liu; Shannon Elf; Yasuhiko Miyata; Kazuma Ohyashiki; Miki Izumi; Silvia Menendez; Stephen D Nimer
ELF4/MEF activates MDM2 expression and blocks oncogene-induced p16 activation to promote transformation.
Molecular and cellular biology 2009;29(13):3687-99.
2009: Jie Gao; Stephanie Graves; Ute Koch; Suqing Liu; Vladimir Jankovic; Silvia Buonamici; Abdeljabar El Andaloussi; Stephen D Nimer; Barbara L Kee; Russell Taichman; Freddy Radtke; Ioannis Aifantis
Hedgehog signaling is dispensable for adult hematopoietic stem cell function.
Cell stem cell 2009;4(6):548-58.
2009: Hui-Kuan Lin; Guocan Wang; Zhenbang Chen; Julie T Feldstein; Yan Liu; Chia-Hsin Chan; Wei-Lei Yang; Hediye Erdjument-Bromage; Keiichi I Nakayama; Stephen D Nimer; Paul Tempst; Pier Paolo Pandolfi
Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB.
Nature cell biology 2009;11(4):420-32.
2009: Yan Liu; Shannon E Elf; Yasuhiko Miyata; Goro Sashida; Yuhui Liu; Gang Huang; Silvana Di giandomenico; Jennifer M Lee; Anthony Deblasio; Silvia Menendez; Jack Antipin; Boris Reva; Andrew Koff; Stephen D Nimer
p53 regulates hematopoietic stem cell quiescence.
Cell stem cell 2009;4(1):37-48.
2008: Peter L Greenberg; Eyal Attar; Minoo Battiwalla; John M Bennett; Clara D Bloomfield; Carlos M DeCastro; H Joachim Deeg; Harry P Erba; James M Foran; Guillermo Garcia-Manero; Steven D Gore; David Head; Lori J Maness; Michael Millenson; Stephen D Nimer; Margaret R O'Donnell; Hussain I Saba; Paul J Shami; Kathy Spiers; Richard M Stone; Martin S Tallman; Peter Westervelt
Myelodysplastic syndromes.
Journal of the National Comprehensive Cancer Network : JNCCN 2008;6(9):902-26.
2008: Luca Malcovati; Stephen D Nimer
Myelodysplastic syndromes: diagnosis and staging.
Cancer control : journal of the Moffitt Cancer Center 2008;15 Suppl():4-13.
2008: Asad Bashey; Waleska S Pérez; Mei-Jie Zhang; Kenneth C Anderson; Karen Ballen; James R Berenson; L Bik To; Rafael Fonseca; Cesar O Freytes; Robert Peter Gale; John Gibson; Sergio Giralt; Robert A Kyle; Hillard M Lazarus; Dipnarine Maharaj; Philip L McCarthy; Gustavo A Milone; Stephen D Nimer; Santiago Pavlovsky; Donna Reece; Gary Schiller; David H Vesole; Parameswaran Hari
Comparison of twin and autologous transplants for multiple myeloma.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2008;14(10):1118-24.
2008: Hani Hassoun; Carlos D Flombaum; V D D'Agati; B T Rafferty; A Cohen; Virginia Klimek; A Boruchov; T Kewalramani; L Reich; Stephen D Nimer; R L Comenzo
High-dose melphalan and auto-SCT in patients with monoclonal Ig deposition disease.
Bone marrow transplantation 2008;42(6):405-12.
2008: H Becker; D Pfeifer; J D Afonso; Stephen D Nimer; H Veelken; M Schwabe; M Lübbert
Two cell lines of t(8;21) acute myeloid leukemia with activating KIT exon 17 mutation: models for the 'second hit' hypothesis.
Leukemia 2008;22(9):1792-4.
2008: Nagesh Kalakonda; W Fischle; Piernicola Boccuni; N Gurvich; R Hoya-Arias; xinyang zhao; Y Miyata; Donal MacGrogan; Jianjun Zhang; J K Sims; J C Rice; Stephen D Nimer
Histone H4 lysine 20 monomethylation promotes transcriptional repression by L3MBTL1.
Oncogene 2008;27(31):4293-304.
2008: Benjamin J Thompson; Vladimir Jankovic; Jie Gao; Silvia Buonamici; Alan Vest; Jennifer May Lee; Jiri Zavadil; Stephen D Nimer; Ioannis Aifantis
Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7.
The Journal of experimental medicine 2008;205(6):1395-408.
2008: Stephen D Nimer
Myelodysplastic syndromes.
Blood 2008;111(10):4841-51.
2008: Monica Morales; Yan Liu; Evagelia C Laiakis; William F Morgan; Stephen D Nimer; John H J Petrini
DNA damage signaling in hematopoietic cells: a role for Mre11 complex repair of topoisomerase lesions.
Cancer research 2008;68(7):2186-93.
2008: Hugo Castro-Malaspina; Ann A Jabubowski; Esperanza B Papadopoulos; Farid Boulad; James W Young; Nancy A Kernan; Miguel-Angel Perales; Trudy N Small; Katharine C Hsu; Michelle Chiu; Glenn Heller; Nancy H Collins; Suresh C Jhanwar; Marcel R M van den Brink; Stephen D Nimer; Richard J O'Reilly
Transplantation in remission improves the disease-free survival of patients with advanced myelodysplastic syndromes treated with myeloablative T cell-depleted stem cell transplants from HLA-identical siblings.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2008;14(4):458-68.
2008: Ping Zhou; Raymond Comenzo; Adam B Olshen; Ezio Bonvini; Scott Koenig; Peter Maslak; Martin Fleisher; James Hoffman; Suresh C Jhanwar; James W Young; Stephen D Nimer; Adam M Boruchov
CD32B is highly expressed on clonal plasma cells from patients with systemic light-chain amyloidosis and provides a target for monoclonal antibody-based therapy.
Blood 2008;111(7):3403-6.
2008: Stephen D Nimer
Is it important to decipher the heterogeneity of "normal karyotype AML"?
Best practice & research. Clinical haematology 2008;21(1):43-52.
2008: xinyang zhao; Vlaidmir Jankovic; Alexander Gural; Gang Huang; Animesh Pardanani; Silvia Menendez; J Zhang; Richard Dunne; Andrew Xiao; Hediye Erdjument-Bromage; C David Allis; Paul Tempst; Stephen D Nimer
Methylation of RUNX1 by PRMT1 abrogates SIN3A binding and potentiates its transcriptional activity.
Genes & development 2008;22(5):640-53.
2008: Virginia Klimek; Sophia Fircanis; Peter Maslak; Ilhem Guernah; Michael Baum; Nian Wu; Katherine S Panageas; John J Wright; Pier Paolo Pandolfi; Stephen D Nimer
Tolerability, pharmacodynamics, and pharmacokinetics studies of depsipeptide (romidepsin) in patients with acute myelogenous leukemia or advanced myelodysplastic syndromes.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(3):826-32.
2008: Richard F Schlenk; Marcelo C Pasquini; Waleska S Pérez; Mei-Jie Zhang; Jürgen Krauter; Joseph H Antin; Asad Bashey; Brian J Bolwell; Thomas Büchner; Jean-Yves Cahn; Mitchell S Cairo; Edward A Copelan; Corey Cutler; Hartmut Döhner; Robert Peter Gale; Osman Ilhan; Hillard M Lazarus; Jane L Liesveld; Mark R Litzow; David I Marks; Richard T Maziarz; Philip L McCarthy; Stephen D Nimer; Jorge Sierra; Martin S Tallman; Daniel J Weisdorf; Mary M Horowitz; Arnold Ganser
HLA-identical sibling allogeneic transplants versus chemotherapy in acute myelogenous leukemia with t(8;21) in first complete remission: collaborative study between the German AML Intergroup and CIBMTR.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2008;14(2):187-96.
2008: Stephen D Nimer
MDS: a stem cell disorder--but what exactly is wrong with the primitive hematopoietic cells in this disease?
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2008;():43-51.
2008: Gang Huang; Pu Zhang; Hideyo Hirai; Shannon Elf; Xiaomei Yan; Zhao Chen; Steffen Koschmieder; Yutaka Okuno; Tajhal Dayaram; Joseph D Growney; Ramesh A Shivdasani; D Gary Gilliland; Nancy A Speck; Stephen D Nimer; Daniel G Tenen
PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis.
Nature genetics 2008;40(1):51-60.
2007: Craig Moskowitz; Paul A Hamlin; JL Gabrilove; Joseph R Bertino; Carol S Portlock; David J Straus; Alison Gencarelli; Stephen D Nimer; Andrew D Zelenetz
Maintaining the dose intensity of ICE chemotherapy with a thrombopoietic agent, PEG-rHuMGDF, may confer a survival advantage in relapsed and refractory aggressive non-Hodgkin lymphoma.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2007;18(11):1842-50.
2007: Adam D Cohen; Ping Zhou; Joanne Chou; Julie T Feldstein; Lilian Reich; Hani Hassoun; Beth Levine; Daniel A Filippa; Elyn Riedel; Tarun Kewalramani; Michael D Stubblefield; Martin Fleisher; Stephen D Nimer; Raymond Comenzo
Risk-adapted autologous stem cell transplantation with adjuvant dexamethasone +/- thalidomide for systemic light-chain amyloidosis: results of a phase II trial.
British journal of haematology 2007;139(2):224-33.
2007: J J Yao; Yan Liu; H Daniel Lacorazza; Robert A Soslow; Joseph Michael Scandura; Stephen D Nimer; Cyrus V Hedvat
Tumor promoting properties of the ETS protein MEF in ovarian cancer.
Oncogene 2007;26(27):4032-7.
2007: Patrick Trojer; Guohong Li; Robert J Sims; Alejandro Vaquero; Nagesh Kalakonda; Piernicola Boccuni; Donghoon Lee; Hediye Erdjument-Bromage; Paul Tempst; Stephen D Nimer; Yuh-Hwa Wang; Danny Reinberg
L3MBTL1, a histone-methylation-dependent chromatin lock.
Cell 2007;129(5):915-28.
2007: Ruben A Mesa; Srdan Verstovsek; Francisco Cervantes; Giovanni Barosi; John T Reilly; Brigitte Dupriez; Ross Levine; Marie-Caroline Le Bousse-Kerdiles; Martha Wadleigh; Peter J Campbell; Richard T Silver; Alessandro M Vannucchi; H Joachim Deeg; Heinz Gisslinger; Deborah Thomas; Olatoyosi Odenike; Lawrence Solberg; Jason Gotlib; Elizabeth Hexner; Stephen D Nimer; Andrew Lamb; Attilio Orazi; James W Vardiman; Juergen Thiele; Ayalew Tefferi
Primary myelofibrosis (PMF), post polycythemia vera myelofibrosis (post-PV MF), post essential thrombocythemia myelofibrosis (post-ET MF), blast phase PMF (PMF-BP): Consensus on terminology by the international working group for myelofibrosis research and treatment (IWG-MRT).
Leukemia research 2007;31(6):737-40.
2007: Ting-Lei Gu; Lana Popova; Cynthia Reeves; Julie Nardone; Joan MacNeill; John Rush; Stephen D Nimer; Roberto D Polakiewicz
Phosphoproteomic analysis identifies the M0-91 cell line as a cellular model for the study of TEL-TRKC fusion-associated leukemia.
Leukemia 2007;21(3):563-6.
2007: Vlaidmir Jankovic; Alessia Ciarrocchi; Piernicola Boccuni; Tony DeBlasio; Robert Benezra; Stephen D Nimer
Id1 restrains myeloid commitment, maintaining the self-renewal capacity of hematopoietic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(4):1260-5.
2007: Alessia Ciarrocchi; Vlaidmir Jankovic; Yuval Shaked; Daniel J Nolan; Vivek Mittal; Robert S Kerbel; Stephen D Nimer; Robert Benezra
Id1 restrains p21 expression to control endothelial progenitor cell formation.
PloS one 2007;2(12):e1338.
2006: Daniel J DeAngelo; Richard M Stone; Mark L Heaney; Stephen D Nimer; Ronald L Paquette; Rebecca B Klisovic; Michael A Caligiuri; Michael R Cooper; Jean-Michel Lecerf; Michael D Karol; Shihong Sheng; Nick Holford; Peter T Curtin; Brian J Druker; Michael C Heinrich
Phase 1 clinical results with tandutinib (MLN518), a novel FLT3 antagonist, in patients with acute myelogenous leukemia or high-risk myelodysplastic syndrome: safety, pharmacokinetics, and pharmacodynamics.
Blood 2006;108(12):3674-81.
2006: Bruce D Cheson; Peter L Greenberg; John M Bennett; Bob Lowenberg; Pierre W Wijermans; Stephen D Nimer; Antonio Pinto; Miloslav Beran; Theo M de Witte; Richard M Stone; Moshe Mittelman; Guillermo F Sanz; Steven D Gore; Charles Alan Schiffer; Andrew Lamb
Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia.
Blood 2006;108(2):419-25.
2006: David H Chang; Nancy Liu; Virginia Klimek; Hani Hassoun; Amitabha Mazumder; Stephen D Nimer; Sundar Jagannath; Madhav V Dhodapkar
Enhancement of ligand-dependent activation of human natural killer T cells by lenalidomide: therapeutic implications.
Blood 2006;108(2):618-21.
2006: Tarun Kewalramani; Andrew D Zelenetz; Julie T Feldstein; Paul A Hamlin; Joachim Yahalom; Steven Horwitz; Stephen D Nimer; Craig Moskowitz
Autologous transplantation for relapsed or primary refractory peripheral T-cell lymphoma.
British journal of haematology 2006;134(2):202-7.
2006: Stephen D Nimer
Clinical management of myelodysplastic syndromes with interstitial deletion of chromosome 5q.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(16):2576-82.
2006: Thomas Pabst; Erica Stillner; Donna Neuberg; Stephen D Nimer; Cheryl L Willman; Alan F List; Junia V Melo; Daniel G Tenen; Beatrice U Mueller
Mutations of the myeloid transcription factor CEBPA are not associated with the blast crisis of chronic myeloid leukaemia.
British journal of haematology 2006;133(4):400-2.
2006: Andrew Lamb; Jean-Pierre J Issa; Craig S Rosenfeld; John M Bennett; Maher Albitar; John DiPersio; Virginia Klimek; James Slack; Carlos de Castro; Farhad Ravandi; Richard Helmer; Lanlan Shen; Stephen D Nimer; Richard Leavitt; Azra Raza; Hussain I Saba
Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study.
Cancer 2006;106(8):1794-803.
2006: Yan Liu; Cyrus V Hedvat; Shifeng Mao; Xin-Hua Zhu; Jinjuan Yao; Hoang Nguyen; Andrew Koff; Stephen D Nimer
The ETS protein MEF is regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCFSkp2.
Molecular and cellular biology 2006;26(8):3114-23.
2006: Lauren E Abrey; Barrett H Childs; Nina Paleologos; Lynne Kaminer; Steven Rosenfeld; Donna Salzman; Jonathan Lester Finlay; Sharon L Gardner; Kendra Peterson; Wendy Hu; Lode Swinnen; Robert Bayer; Peter A Forsyth; Douglas Stewart; Anne M Smith; David R Macdonald; Susan Weaver; David A Ramsay; Stephen D Nimer; Lisa De Angelis; J Gregory Cairncross
High-dose chemotherapy with stem cell rescue as initial therapy for anaplastic oligodendroglioma: long-term follow-up.
Neuro-oncology 2006;8(2):183-8.
2006: H Daniel Lacorazza; Takeshi Yamada; Yan Liu; Yasuhiko Miyata; Mariela Sivina; Juliana Nunes; Stephen D Nimer
The transcription factor MEF/ELF4 regulates the quiescence of primitive hematopoietic cells.
Cancer cell 2006;9(3):175-87.
2006: Peter Maslak; Suzanne M Chanel; Luis H Camacho; Steven L Soignet; Pier Paolo Pandolfi; I Guernah; RP Warrell; Stephen D Nimer
Pilot study of combination transcriptional modulation therapy with sodium phenylbutyrate and 5-azacytidine in patients with acute myeloid leukemia or myelodysplastic syndrome.
Leukemia 2006;20(2):212-7.
2006: Raymond Comenzo; Hani Hassoun; Tarun Kewalramani; Virginia Klimek; Madhav V Dhodapkar; Lilian Reich; Julie T Feldstein; Martin Fleisher; Daniel A Filippa; Stephen D Nimer
Results of a phase I/II trial adding carmustine (300 mg/m2) to melphalan (200 mg/m2) in multiple myeloma patients undergoing autologous stem cell transplantation.
Leukemia 2006;20(2):345-9.
2006: Ra Tuma; Ng Almyroudis; Sj Sohn; Katherine S Panageas; Rd Rice; D Galinkin; M Blain; M Montefusco; Eric G Pamer; Stephen D Nimer; Tarun Kewalramani
The serum IL-12:IL-6 ratio reliably distinguishes infectious from non-infectious causes of fever during autologous stem cell transplantation.
Cytotherapy 2006;8(4):327-34.
2006: Peter L Greenberg; Maria R Baer; John M Bennett; Clara D Bloomfield; Carlos M De Castro; H Joachim Deeg; Marcel P Devetten; Peter D Emanuel; Harry P Erba; Eli Estey; James Foran; Steven D Gore; Michael Millenson; Willlis H Navarro; Stephen D Nimer; Margaret R O'Donnell; Hussain I Saba; Kathy Spiers; Richard M Stone; Martin S Tallman
Myelodysplastic syndromes clinical practice guidelines in oncology.
Journal of the National Comprehensive Cancer Network : JNCCN 2006;4(1):58-77.
2006: Hani Hassoun; Lilian Reich; Virginia Klimek; Madhav V Dhodapkar; Adam Cohen; Tarun Kewalramani; Rachel Zimman; Lisa Drake; Elyn Riedel; Cyrus V Hedvat; Julie T Feldstein; Daniel A Filippa; Martin Fleisher; Stephen D Nimer; Raymond Comenzo
Doxorubicin and dexamethasone followed by thalidomide and dexamethasone is an effective well tolerated initial therapy for multiple myeloma.
British journal of haematology 2006;132(2):155-61.
2006: Florian Heidel; Fian K Solem; Frank Breitenbuecher; Daniel B Lipka; Stefan Kasper; M H Thiede; Christian Brandts; Hubert Serve; Johannes Roesel; Francis Giles; Eric Feldman; Gerhard Ehninger; Gary J Schiller; Stephen D Nimer; Richard M Stone; Yanfeng Wang; Thomas Kindler; Pamela S Cohen; Christoph Huber; Thomas Fischer
Clinical resistance to the kinase inhibitor PKC412 in acute myeloid leukemia by mutation of Asn-676 in the FLT3 tyrosine kinase domain.
Blood 2006;107(1):293-300.
2005: Craig Moskowitz; Andrew D Zelenetz; Tarun Kewalramani; Paul A Hamlin; Simone Lessac-Chenen; Jane Houldsworth; Adam B Olshen; Raju S K Chaganti; Stephen D Nimer; Julie T Feldstein
Cell of origin, germinal center versus nongerminal center, determined by immunohistochemistry on tissue microarray, does not correlate with outcome in patients with relapsed and refractory DLBCL.
Blood 2005;106(10):3383-5.
2005: Ying-Wei Lin; Ramona Deveney; Mary Barbara; Norman N Iscove; Stephen D Nimer; Christopher Slape; Peter D Aplan
OLIG2 (BHLHB1), a bHLH transcription factor, contributes to leukemogenesis in concert with LMO1.
Cancer research 2005;65(16):7151-8.
2005: Hao Zhu; David Traver; Alan J Davidson; Anthony Dibiase; Christine Thisse; Bernard Thisse; Stephen D Nimer; Leonard I Zon
Regulation of the lmo2 promoter during hematopoietic and vascular development in zebrafish.
Developmental biology 2005;281(2):256-69.
2005: Yelena Janjigian; Stephen D Nimer
A role for Wnt signaling in adult T-cell leukemia?
Leukemia research 2005;29(5):475-6.
2005: James C Mulloy; Vlaidmir Jankovic; Mark Wunderlich; Ruud Delwel; Jörg Cammenga; Ondrej Krejci; Hui Zhao; Peter J M Valk; Bob Lowenberg; Stephen D Nimer
AML1-ETO fusion protein up-regulates TRKA mRNA expression in human CD34+ cells, allowing nerve growth factor-induced expansion.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(11):4016-21.
2005: S Gupta; Ping Zhou; Hani Hassoun; Tarun Kewalramani; Lilian Reich; S Costello; L Drake; Virginia Klimek; Madhav V Dhodapkar; Julie T Feldstein; Cyrus V Hedvat; Nagesh Kalakonda; Martin Fleisher; Daniel A Filippa; Jing Qin; Stephen D Nimer; Raymond Comenzo
Hematopoietic stem cell mobilization with intravenous melphalan and G-CSF in patients with chemoresponsive multiple myeloma: report of a phase II trial.
Bone marrow transplantation 2005;35(5):441-7.
2005: Richard M Stone; Daniel J DeAngelo; Virginia Klimek; Ilene Galinsky; Elihu Estey; Stephen D Nimer; Wilson Grandin; David Lebwohl; Yanfeng Wang; Pamela Cohen; Edward A Fox; Donna Neuberg; Jennifer Clark; D Gary Gilliland; James D Griffin
Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412.
Blood 2005;105(1):54-60.
2005: Thomas Kindler; Frank Breitenbuecher; Stefan Kasper; Elihu Estey; Francis Giles; Eric Feldman; Gerhard Ehninger; Gary Schiller; Virginia Klimek; Stephen D Nimer; Alois Gratwohl; Chunaram Choudhary; Constan Mueller-Tidow; Hubert Serve; Harald Gschaidmeier; Pamela S Cohen; Christoph Huber; Thomas Fischer
Identification of a novel activating mutation (Y842C) within the activation loop of FLT3 in patients with acute myeloid leukemia (AML).
Blood 2005;105(1):335-40.
2004: Monica Garcia-Barros; Daniel Lacorazza; Howard Petrie; Adriana Haimovitz-Friedman; Carlos Cardon-Cardo; Stephen D Nimer; Zvi Fuks; Richard Kolesnick
Host acid sphingomyelinase regulates microvascular function not tumor immunity.
Cancer research 2004;64(22):8285-91.
2004: Donal MacGrogan; Nagesh Kalakonda; Sara Alvarez; Joseph Michael Scandura; Piernicola Boccuni; Bertil Johansson; Stephen D Nimer
Structural integrity and expression of the L3MBTL gene in normal and malignant hematopoietic cells.
Genes, chromosomes & cancer 2004;41(3):203-13.
2004: Joseph Michael Scandura; Piernicola Boccuni; Joan Massagué; Stephen D Nimer
Transforming growth factor beta-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(42):15231-6.
2004: Anja Moldenhauer; Richard C Frank; Javier Pinilla-Ibarz; Gudrun Holland; Piernicola Boccuni; David A Scheinberg; Abdulgabar Salama; Karl Seeger; Malcolm A S Moore; Stephen D Nimer
Histone deacetylase inhibition improves dendritic cell differentiation of leukemic blasts with AML1-containing fusion proteins.
Journal of leukocyte biology 2004;76(3):623-33.
2004: Keiko Asakura; Hideo Uchida; Hayato Miyachi; Hiroyuki Kobayashi; Yoshitaka Miyakawa; Stephen D Nimer; Hiroyuki Takahashi; Yasuo Ikeda; Masahiro Kizaki
TEL/AML1 overcomes drug resistance through transcriptional repression of multidrug resistance-1 gene expression.
Molecular cancer research : MCR 2004;2(6):339-47.
2004: Stephen D Nimer; Malcolm A S Moore
Effects of the leukemia-associated AML1-ETO protein on hematopoietic stem and progenitor cells.
Oncogene 2004;23(24):4249-54.
2004: Tarun Kewalramani; Andrew D Zelenetz; Stephen D Nimer; Carol S Portlock; David J Straus; Ariela Noy; Owen A O'Connor; Daniel A Filippa; Julie T Feldstein; Alison Gencarelli; Jing Qin; Alyson Waxman; Joachim Yahalom; Craig Moskowitz
Rituximab and ICE as second-line therapy before autologous stem cell transplantation for relapsed or primary refractory diffuse large B-cell lymphoma.
Blood 2004;103(10):3684-8.
2004: Carmela Gurrieri; Khedoudja Nafa; Taha Merghoub; Rosa Bernardi; Paola Capodieci; Andrea Biondi; Stephen D Nimer; Dan Douer; Carlos Cordon-Cardo; Robert E Gallagher; Pier Paolo Pandolfi
Mutations of the PML tumor suppressor gene in acute promyelocytic leukemia.
Blood 2004;103(6):2358-62.
2004: Craig Moskowitz; Tarun Kewalramani; Stephen D Nimer; Maria Gonzalez; Andrew D Zelenetz; Joachim Yahalom
Effectiveness of high dose chemoradiotherapy and autologous stem cell transplantation for patients with biopsy-proven primary refractory Hodgkin's disease.
British journal of haematology 2004;124(5):645-52.
2004: Cyrus V Hedvat; JinJuan Yao; Robert A Sokolic; Stephen D Nimer
Myeloid ELF1-like factor is a potent activator of interleukin-8 expression in hematopoietic cells.
The Journal of biological chemistry 2004;279(8):6395-400.
2004: Julie M Vose; Douglas J Rizzo; Jing Tao-Wu; James O Armitage; Asad Bashey; Linda J Burns; Neal Christiansen; Cesar O Freytes; Robert Peter Gale; John Gibson; Sergio Giralt; Roger H Herzig; Charles F LeMaistre; Philip L McCarthy; Stephen D Nimer; Finn B Petersen; David P Schenkein; Peter H Wiernik; Joseph M Wiley; Fausto R Loberiza; Hillard M Lazarus; Koen van Biesen; Mary M Horowitz
Autologous transplantation for diffuse aggressive non-Hodgkin lymphoma in first relapse or second remission.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2004;10(2):116-27.
2003: James C Mulloy; Jörg Cammenga; Francisco J Berguido; Kaida Wu; Ping Zhou; Raymond Comenzo; Suresh C Jhanwar; Malcolm A S Moore; Stephen D Nimer
Maintaining the self-renewal and differentiation potential of human CD34+ hematopoietic cells using a single genetic element.
Blood 2003;102(13):4369-76.
2003: Donna Reece; Christopher N Bredeson; Waleska S Pérez; Sundar Jagannath; Mei-Jie Zhang; Karen K Ballen; Gerald J Elfenbein; Cesar O Freytes; Robert Peter Gale; Morie A Gertz; J Gibson; Sergio Giralt; Armand Keating; R A Kyle; D Maharaj; D Marcellus; Philip L McCarthy; Gustavo A Milone; Stephen D Nimer; Santiago Pavlovsky; L B To; Daniel J Weisdorf; Peter H Wiernik; J R Wingard; David H Vesole
Autologous stem cell transplantation in multiple myeloma patients <60 vs >/=60 years of age.
Bone marrow transplantation 2003;32(12):1135-43.
2003: Lauren E Abrey; Craig Moskowitz; Warren P Mason; Michael Crump; Douglas Stewart; Peter A Forsyth; Nina Paleologos; Denise D Correa; Nicole D Anderson; Dawn Caron; Andrew D Zelenetz; Stephen D Nimer; Lisa De Angelis
Intensive methotrexate and cytarabine followed by high-dose chemotherapy with autologous stem-cell rescue in patients with newly diagnosed primary CNS lymphoma: an intent-to-treat analysis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(22):4151-6.
2003: Lauren E Abrey; Barrett H Childs; Nina Paleologos; Lynne Kaminer; Steven Rosenfeld; Donna Salzman; Jonathan Lester Finlay; Sharon L Gardner; Kendra Peterson; Wendy Hu; Lode Swinnen; Robert Bayer; Peter A Forsyth; Douglas Stewart; Anne M Smith; David R Macdonald; Susan Weaver; David A Ramsey; Stephen D Nimer; Lisa De Angelis; J Gregory Cairncross
High-dose chemotherapy with stem cell rescue as initial therapy for anaplastic oligodendroglioma.
Journal of neuro-oncology 2003;65(2):127-34.
2003: H Daniel Lacorazza; Stephen D Nimer
The emerging role of the myeloid Elf-1 like transcription factor in hematopoiesis.
Blood cells, molecules & diseases 2003;31(3):342-50.
2003: Tarun Kewalramani; Stephen D Nimer; Andrew D Zelenetz; S Malhotra; Jing Qin; Joachim Yahalom; Craig Moskowitz
Progressive disease following autologous transplantation in patients with chemosensitive relapsed or primary refractory Hodgkin's disease or aggressive non-Hodgkin's lymphoma.
Bone marrow transplantation 2003;32(7):673-9.
2003: Paul A Hamlin; Andrew D Zelenetz; Tarun Kewalramani; Jing Qin; Jaya M Satagopan; David Verbel; Ariela Noy; Carol S Portlock; David J Straus; Joachim Yahalom; Stephen D Nimer; Craig Moskowitz
Age-adjusted International Prognostic Index predicts autologous stem cell transplantation outcome for patients with relapsed or primary refractory diffuse large B-cell lymphoma.
Blood 2003;102(6):1989-96.
2003: Cyrus V Hedvat; Raymond Comenzo; Julie T Feldstein; Adam B Olshen; Scott A Ely; Keren Osman; Yana Zhang; Nagesh Kalakonda; Stephen D Nimer
Insights into extramedullary tumour cell growth revealed by expression profiling of human plasmacytomas and multiple myeloma.
British journal of haematology 2003;122(5):728-44.
2003: Shin-ichiro Fujii; Kanako Shimizu; Virginia Klimek; Matthew D Geller; Stephen D Nimer; Madhav V Dhodapkar
Severe and selective deficiency of interferon-gamma-producing invariant natural killer T cells in patients with myelodysplastic syndromes.
British journal of haematology 2003;122(4):617-22.
2003: Ping Zhou; Yana Zhang; Carmen Martinez; Nagesh Kalakonda; Stephen D Nimer; Raymond Comenzo
Melphalan-mobilized blood stem cell components contain minimal clonotypic myeloma cell contamination.
Blood 2003;102(2):477-9.
2003: Wooi Koon Wang; Valentina Tereshko; Piernicola Boccuni; Donal MacGrogan; Stephen D Nimer; Dinshaw J Patel
Malignant brain tumor repeats: a three-leaved propeller architecture with ligand/peptide binding pockets.
Structure (London, England : 1993) 2003;11(7):775-89.
2003: Takuya Fukushima; Yasushi Miyazaki; Hideki Tsushima; Chizuko Tsutsumi; Jun Taguchi; Shinichiro Yoshida; Kazutaka Kuriyama; David T Scadden; Stephen D Nimer; Masao Tomonaga
The level of MEF but not ELF-1 correlates with FAB subtype of acute myeloid leukemia and is low in good prognosis cases.
Leukemia research 2003;27(5):387-92.
2003: Piernicola Boccuni; Donal MacGrogan; Joseph Michael Scandura; Stephen D Nimer
The human L(3)MBT polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6).
The Journal of biological chemistry 2003;278(17):15412-20.
2003: Juan C Cigudosa; María D Odero; María J Calasanz; Francesc Solé; Marta Salido; Eva Arranz; Angel Martínez-Ramirez; Miguel Urioste; Sara Alvarez; Jose V Cervera; Donal MacGrogan; Miguel A Sanz; Stephen D Nimer; Javier Benitez
De novo erythroleukemia chromosome features include multiple rearrangements, with special involvement of chromosomes 11 and 19.
Genes, chromosomes & cancer 2003;36(4):406-12.
2003: Jörg Cammenga; James C Mulloy; Francisco J Berguido; Donal MacGrogan; Agnes Viale; Stephen D Nimer
Induction of C/EBPalpha activity alters gene expression and differentiation of human CD34+ cells.
Blood 2003;101(6):2206-14.
2003: Andrew D Zelenetz; Paul A Hamlin; Tarun Kewalramani; Joachim Yahalom; Stephen D Nimer; Craig Moskowitz
Ifosfamide, carboplatin, etoposide (ICE)-based second-line chemotherapy for the management of relapsed and refractory aggressive non-Hodgkin's lymphoma.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2003;14 Suppl 1():i5-10.
2002: Caroline Erter Burns; Tony DeBlasio; Yi Zhou; Jin Zhang; Leonard I Zon; Stephen D Nimer
Isolation and characterization of runxa and runxb, zebrafish members of the runt family of transcriptional regulators.
Experimental hematology 2002;30(12):1381-9.
2002: Stephen D Nimer; Donal MacGrogan; Suresh C Jhanwar; Sara Alvarez
Chromosome 19 abnormalities are commonly seen in AML, M7.
Blood 2002;100(10):3838; author reply 3838-9.
2002: Sara Alvarez; Donal MacGrogan; Sandra Rodriguez-Perales; Angel Martinez-Ramirez; Miguel Urioste; Javier Benitez; Stephen D Nimer; Juan C Cigudosa
Cytogenetic characterization reveals that the SAM-1 erythroid cell line is derived from K-562 cells.
Blood 2002;100(9):3435-6.
2002: Cyrus V Hedvat; Abhijith Hegde; Raju S K Chaganti; Beiyun Chen; Jing Qin; Daniel A Filippa; Stephen D Nimer; Julie T Feldstein
Application of tissue microarray technology to the study of non-Hodgkin's and Hodgkin's lymphoma.
Human pathology 2002;33(10):968-74.
2002: H Daniel Lacorazza; Yasushi Miyazaki; Antonio Di Cristofano; Anthony Deblasio; Cyrus V Hedvat; Jin Zhang; Carlos Cordon-Cardo; Shifeng Mao; Pier Paolo Pandolfi; Stephen D Nimer
The ETS protein MEF plays a critical role in perforin gene expression and the development of natural killer and NK-T cells.
Immunity 2002;17(4):437-49.
2002: Joseph Michael Scandura; Piernicola Boccuni; Jörg Cammenga; Stephen D Nimer
Transcription factor fusions in acute leukemia: variations on a theme.
Oncogene 2002;21(21):3422-44.
2002: Jörg Cammenga; Stephen D Nimer
Mutations in human cancer: how close should we look?
Leukemia research 2002;26(5):459-60.
2002: James C Mulloy; Jörg Cammenga; Karen L MacKenzie; Francisco J Berguido; Malcolm A S Moore; Stephen D Nimer
The AML1-ETO fusion protein promotes the expansion of human hematopoietic stem cells.
Blood 2002;99(1):15-23.
2001: Cyrus V Hedvat; E S Jaffe; Jing Qin; Daniel A Filippa; Carlos Cordon-Cardo; G Tosato; Stephen D Nimer; Julie T Feldstein
Macrophage-derived chemokine expression in classical Hodgkin's lymphoma: application of tissue microarrays.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2001;14(12):1270-6.
2001: Y Miyazaki; Piernicola Boccuni; Shifeng Mao; Jianjun Zhang; Hediye Erdjument-Bromage; Paul Tempst; Hiroaki Kiyokawa; Stephen D Nimer
Cyclin A-dependent phosphorylation of the ETS-related protein, MEF, restricts its activity to the G1 phase of the cell cycle.
The Journal of biological chemistry 2001;276(44):40528-36.
2001: Joseph G Jurcic; Stephen D Nimer; David A Scheinberg; Tony DeBlasio; RP Warrell; W H Miller
Prognostic significance of minimal residual disease detection and PML/RAR-alpha isoform type: long-term follow-up in acute promyelocytic leukemia.
Blood 2001;98(9):2651-6.
2001: Sara Alvarez; Donal MacGrogan; María J Calasanz; Stephen D Nimer; Suresh C Jhanwar
Frequent gain of chromosome 19 in megakaryoblastic leukemias detected by comparative genomic hybridization.
Genes, chromosomes & cancer 2001;32(3):285-93.
2001: Bruce D Cheson; John M Bennett; Andrew Lamb; Charles Alan Schiffer; Stephen D Nimer; B Löwenberg; Richard M Stone; Moshe Mittelman; Guillermo F Sanz; Pierre W Wijermans; Peter L Greenberg
Myelodysplastic syndromes standardized response criteria: further definition.
Blood 2001;98(6):1985.
2001: Donal MacGrogan; Sara Alvarez; Tony DeBlasio; Suresh C Jhanwar; Stephen D Nimer
Identification of candidate genes on chromosome band 20q12 by physical mapping of translocation breakpoints found in myeloid leukemia cell lines.
Oncogene 2001;20(31):4150-60.
2001: Craig Moskowitz; Stephen D Nimer; Andrew D Zelenetz; Tanya M Trippett; Eric Hedrick; Daniel A Filippa; Diane C Louie; M Gonzales; J Walits; N Coady-Lyons; Jing Qin; R Frank; Joseph R Bertino; Andre Goy; Ariela Noy; JP O'Brien; David J Straus; Carol S Portlock; Joachim Yahalom
A 2-step comprehensive high-dose chemoradiotherapy second-line program for relapsed and refractory Hodgkin disease: analysis by intent to treat and development of a prognostic model.
Blood 2001;97(3):616-23.
2000: Andrzej J Jakubowiak; C Pouponnot; Francisco J Berguido; R Frank; Shifeng Mao; Joan Massague; Stephen D Nimer
Inhibition of the transforming growth factor beta 1 signaling pathway by the AML1/ETO leukemia-associated fusion protein.
The Journal of biological chemistry 2000;275(51):40282-7.
2000: Bruce D Cheson; John M Bennett; Andrew Lamb; A Pinto; Charles Alan Schiffer; Stephen D Nimer; B Löwenberg; M Beran; T M de Witte; Richard M Stone; Moshe Mittelman; Guillermo F Sanz; Pierre W Wijermans; Steven D Gore; Peter L Greenberg
Report of an international working group to standardize response criteria for myelodysplastic syndromes.
Blood 2000;96(12):3671-4.
2000: Mark L Heaney; Stephen D Nimer
Review of the Cox hematotoxicity model.
Journal of toxicology and environmental health. Part A 2000;61(5-6):539-41.
2000: Tarun Kewalramani; Andrew D Zelenetz; Eric Hedrick; Gerard B Donnelly; S Hunte; A C Priovolos; Jing Qin; N C Lyons; Joachim Yahalom; Stephen D Nimer; Craig Moskowitz
High-dose chemoradiotherapy and autologous stem cell transplantation for patients with primary refractory aggressive non-Hodgkin lymphoma: an intention-to-treat analysis.
Blood 2000;96(7):2399-404.
2000: Andrzej J Jakubowiak; Jörg Cammenga; Robert A Sokolic; S Alvarez; G Jackson; Cyrus V Hedvat; Stephen D Nimer
Molecular biology of leukemia.
Current oncology reports 2000;2(2):123-31.
2000: Richard A Nash; R Kurzrock; John DiPersio; Julie M Vose; Charles Linker; D Maharaj; Auayporn Nademanee; R Negrin; Stephen D Nimer; Howard M Shulman; Mark Ashby; Denny Jones; Frederick R Appelbaum; Richard Champlin
A phase I trial of recombinant human thrombopoietin in patients with delayed platelet recovery after hematopoietic stem cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2000;6(1):25-34.
1999: Craig Moskowitz; Joseph R Bertino; Jill Glassman; Eric Hedrick; S Hunte; N Coady-Lyons; David B Agus; Andre Goy; Joseph G Jurcic; Ariela Noy; J O'Brien; Carol S Portlock; D S Straus; Barrett H Childs; R Frank; Joachim Yahalom; Daniel A Filippa; Diane C Louie; Stephen D Nimer; Andrew D Zelenetz
Ifosfamide, carboplatin, and etoposide: a highly effective cytoreduction and peripheral-blood progenitor-cell mobilization regimen for transplant-eligible patients with non-Hodgkin's lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(12):3776-85.
1999: Lidija Klampfer; J Zhang; Stephen D Nimer
GM-CSF rescues TF-1 cells from growth factor withdrawal-induced, but not differentiation-induced apoptosis: the role of BCL-2 and MCL-1.
Cytokine 1999;11(11):849-55.
1999: Shifeng Mao; Richard C Frank; J Zhang; Y Miyazaki; Stephen D Nimer
Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias.
Molecular and cellular biology 1999;19(5):3635-44.
1999: Lidija Klampfer; Jörg Cammenga; H G Wisniewski; Stephen D Nimer
Sodium salicylate activates caspases and induces apoptosis of myeloid leukemia cell lines.
Blood 1999;93(7):2386-94.
1999: Richard C Frank; X Sun; Francisco J Berguido; Andrzej J Jakubowiak; Stephen D Nimer
The t(8;21) fusion protein, AML1/ETO, transforms NIH3T3 cells and activates AP-1.
Oncogene 1999;18(9):1701-10.
1999: Craig Moskowitz; Stephen D Nimer; Jill Glassman; Carol S Portlock; Joachim Yahalom; David J Straus; JP O'Brien; N Elkin; Joseph R Bertino; Andrew D Zelenetz
The International Prognostic Index predicts for outcome following autologous stem cell transplantation in patients with relapsed and primary refractory intermediate-grade lymphoma.
Bone marrow transplantation 1999;23(6):561-7.
1999: H Uchida; J R Downing; Y Miyazaki; R Frank; J Zhang; Stephen D Nimer
Three distinct domains in TEL-AML1 are required for transcriptional repression of the IL-3 promoter.
Oncogene 1999;18(4):1015-22.
1999: Stephen D Nimer
Essential thrombocythemia: another "heterogeneous disease" better understood?
Blood 1999;93(2):415-6.
1999: James L Gajewski; Stephen D Nimer; Rima M Saliba; Melanie Thomas; Donna Przepiorka; Sergio Giralt; K von Besien; RC Mehra; Borje Andersson; Ka Wah Chan; Cindy Ippoliti; D Warkinten; S Feigs; Mary Territo; Gary J Schiller; J Lebkowski; A M Moseley; K Lloyd; M von Hoeff; T Okarma; Richard Champlin
Long-term outcome of a phase II study of BM transplants, partially depleted ex-vivo of CD5-positive and CD8-positive T-lymphocytes in unrelated and related donor 1 antigen mismatched recipients.
Cytotherapy 1999;1(5):401-7.
1998: Peter Maslak; Stephen D Nimer
The efficacy of IL-3, SCF, IL-6, and IL-11 in treating thrombocytopenia.
Seminars in hematology 1998;35(3):253-60.
1998: Boris Pasche; Y Luo; Pulivarthi H Rao; Stephen D Nimer; Ethan Dmitrovsky; P Caron; Lucio Luzzatto; Kenneth Offit; Carlos Cordon-Cardo; B Renault; Jaya M Satagopan; Vundavalli Murty; Joan Massagué
Type I transforming growth factor beta receptor maps to 9q22 and exhibits a polymorphism and a rare variant within a polyalanine tract.
Cancer research 1998;58(13):2727-32.
1998: Ronald L Paquette; K Kuramoto; L Tran; G Sopher; Stephen D Nimer; J B Zeldis
Hepatitis C virus infection in acquired aplastic anemia.
American journal of hematology 1998;58(2):122-6.
1998: Craig Moskowitz; Jill Glassman; David Wuest; Peter Maslak; Lilian Reich; A Gucciardo; N Coady-Lyons; Andrew D Zelenetz; Stephen D Nimer
Factors affecting mobilization of peripheral blood progenitor cells in patients with lymphoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(2):311-6.
1997: F Shapiro; Tzy-Jyun Yao; Craig Moskowitz; Lilian Reich; David Wuest; S Heimfeld; Ian K McNiece; JL Gabrilove; Stephen D Nimer; Malcolm A S Moore
Effects of prior therapy on the in vitro proliferative potential of stem cell factor plus filgrastim-mobilized CD34-positive progenitor cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(9):1571-8.
1997: Craig Moskowitz; P Stiff; Michael S Gordon; Ian K McNiece; A D Ho; J J Costa; ER Broun; Robert Bayer; M Wyres; J Hill; K Jelaca-Maxwell; Craig Nichols; S L Brown; Stephen D Nimer; JL Gabrilove
Recombinant methionyl human stem cell factor and filgrastim for peripheral blood progenitor cell mobilization and transplantation in non-Hodgkin's lymphoma patients--results of a phase I/II trial.
Blood 1997;89(9):3136-47.
1997: S Ikushima; Takeshi Inukai; Toshiya Inaba; Stephen D Nimer; J L Cleveland; A Thomas Look
Pivotal role for the NFIL3/E4BP4 transcription factor in interleukin 3-mediated survival of pro-B lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2609-14.
1997: H Uchida; J Zhang; Stephen D Nimer
AML1A and AML1B can transactivate the human IL-3 promoter.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(5):2251-8.
1997: Stephen D Nimer
Platelet stimulating agents--off the launching pad.
Nature medicine 1997;3(2):154-5.
1997: M E Greene; B Blumberg; K Kwan; L Hsieh; G L Greene; Stephen D Nimer
Isolation and cloning of human peroxisome proliferator activated receptor gamma cDNA.
Advances in experimental medicine and biology 1997;400A():253-60.
1996: P Greenberg; Ranjana Advani; A Keating; S C Gulati; Stephen D Nimer; R Champlin; Chatchada Karanes; N C Gorin; R L Powles; A Smith; K Lamborn; C Cuffie
GM-CSF accelerates neutrophil recovery after autologous hematopoietic stem cell transplantation.
Bone marrow transplantation 1996;18(6):1057-64.
1996: Lidija Klampfer; J Zhang; Andrew D Zelenetz; H Uchida; Stephen D Nimer
The AML1/ETO fusion protein activates transcription of BCL-2.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(24):14059-64.
1996: Y Miyazaki; X Sun; H Uchida; J Zhang; Stephen D Nimer
MEF, a novel transcription factor with an Elf-1 like DNA binding domain but distinct transcriptional activating properties.
Oncogene 1996;13(8):1721-9.
1996: J D Nosanchuk; Kent A Sepkowitz; R N Pearse; Mary H White; Stephen D Nimer; Donald Armstrong
Infectious complications of autologous bone marrow and peripheral stem cell transplantation for refractory leukemia and lymphoma.
Bone marrow transplantation 1996;18(2):355-9.
1996: Stephen D Nimer; J Zhang; H Avraham; Y Miyazaki
Transcriptional regulation of interleukin-3 expression in megakaryocytes.
Blood 1996;88(1):66-74.
1996: Stephen D Nimer; W Zhang; K Kwan; Y Whang; J Zhang; Y Wang
Adjacent, cooperative elements form a strong, constitutive enhancer in the human granulocyte-macrophage colony-stimulating factor gene.
Blood 1996;87(9):3694-703.
1995: R Frank; J Zhang; H Uchida; S Meyers; S W Hiebert; Stephen D Nimer
The AML1/ETO fusion protein blocks transactivation of the GM-CSF promoter by AML1B.
Oncogene 1995;11(12):2667-74.
1995: W Zhang; J Zhang; M Kornuc; K Kwan; R Frank; Stephen D Nimer
Molecular cloning and characterization of NF-IL3A, a transcriptional activator of the human interleukin-3 promoter.
Molecular and cellular biology 1995;15(11):6055-63.
1995: Stephen D Nimer; Andrew D Zelenetz; Carol S Portlock
Bone marrow transplantation versus chemotherapy in non-Hodgkin's lymphoma.
The New England journal of medicine 1995;333(11):728-9; author reply 730.
1995: Ronald L Paquette; M R Minosa; M C Verma; Stephen D Nimer; H P Koeffler
An interferon-gamma activation sequence mediates the transcriptional regulation of the IgG Fc receptor type IC gene by interferon-gamma.
Molecular immunology 1995;32(12):841-51.
1995: Stephen D Nimer; H Uchida
Regulation of granulocyte-macrophage colony-stimulating factor and interleukin 3 expression.
Stem cells (Dayton, Ohio) 1995;13(4):324-35.
1995: Michael S Gordon; J Nemunaitis; R Hoffman; Ronald L Paquette; C Rosenfeld; S Manfreda; R Isaacs; Stephen D Nimer
A phase I trial of recombinant human interleukin-6 in patients with myelodysplastic syndromes and thrombocytopenia.
Blood 1995;85(11):3066-76.
1995: Ronald L Paquette; N Tebyani; M Frane; P Ireland; W G Ho; R E Champlin; Stephen D Nimer
Long-term outcome of aplastic anemia in adults treated with antithymocyte globulin: comparison with bone marrow transplantation.
Blood 1995;85(1):283-90.
1995: M E Greene; B Blumberg; O W McBride; H F Yi; K Kronquist; K Kwan; L Hsieh; G Greene; Stephen D Nimer
Isolation of the human peroxisome proliferator activated receptor gamma cDNA: expression in hematopoietic cells and chromosomal mapping.
Gene expression 1995;4(4-5):281-99.
1994: John K Fraser; S Tran; Stephen D Nimer; Judith C Gasson
Characterization of nuclear factors that bind to a critical positive regulatory element of the human granulocyte-macrophage colony-stimulating factor promoter.
Blood 1994;84(8):2523-30.
1994: Stephen D Nimer; Denis H Y Leung; M J Wolin; David W Golde
Serum stem cell factor levels in patients with aplastic anemia.
International journal of hematology 1994;60(3):185-9.
1994: Gary J Schiller; Stephen A Feig; Mary Territo; M Wolin; Michael Lill; Thomas R Belin; L Hunt; Stephen D Nimer; Richard Champlin; James L Gajewski
Treatment of advanced acute leukaemia with allogeneic bone marrow transplantation from unrelated donors.
British journal of haematology 1994;88(1):72-8.
1994: Stephen D Nimer; Ronald L Paquette; P Ireland; D Resta; D Young; David W Golde
A phase I/II study of interleukin-3 in patients with aplastic anemia and myelodysplasia.
Experimental hematology 1994;22(9):875-80.
1994: Stephen D Nimer; P Ireland; A Meshkinpour; M Frane
An increased HLA DR2 frequency is seen in aplastic anemia patients.
Blood 1994;84(3):923-7.
1994: Gary J Schiller; Stephen D Nimer; Robert A Vescio; G Lieb; M Lee; James L Gajewski; Mary Territo; J Berenson
Phase I-II study of busulfan and cyclophosphamide conditioning for transplantation in advanced multiple myeloma.
Bone marrow transplantation 1994;14(1):131-6.
1994: John K Fraser; J J Guerra; C Y Nguyen; J E Indes; Judith C Gasson; Stephen D Nimer
Characterization of a cell-type-restricted negative regulatory activity of the human granulocyte-macrophage colony-stimulating factor gene.
Molecular and cellular biology 1994;14(3):2213-21.
1994: Stephen D Nimer; Janis V Giorgi; James L Gajewski; Nora Ku; Gary J Schiller; K Lee; Mary Territo; W Ho; Stephen A Feig; Michael T Selch
Selective depletion of CD8+ cells for prevention of graft-versus-host disease after bone marrow transplantation. A randomized controlled trial.
Transplantation 1994;57(1):82-7.
1994: LI Chap; Stephen D Nimer
Chronic myelogenous leukemia following repeated radiation therapy for histiocytosis X.
Leukemia & lymphoma 1994;12(3-4):315-6.
1993: Gary J Schiller; Stephen D Nimer; James L Gajewski; M Lee; W Ho; Mary Territo; Richard Champlin
Effect of induction cytarabine dose intensity on long-term survival in acute myelogenous leukemia: results of a randomized, controlled study.
Leukemia & lymphoma 1993;11(1-2):69-77.
1993: LI Chap; Gary J Schiller; Stephen D Nimer
Use of recombinant GM-CSF following allogeneic BMTs for aplastic anemia.
Bone marrow transplantation 1993;12(2):173-5.
1993: M Wolin; M Kornuc; C Hong; S K Shin; F Lee; R Lau; Stephen D Nimer
Differential effect of HTLV infection and HTLV Tax on interleukin 3 expression.
Oncogene 1993;8(7):1905-11.
1993: Gary J Schiller; M Lee; Mary Territo; James L Gajewski; Stephen D Nimer
Phase II study of etoposide, ifosfamide, and mitoxantrone for the treatment of resistant adult acute lymphoblastic leukemia.
American journal of hematology 1993;43(3):195-9.
1992: Gary J Schiller; James L Gajewski; Mary Territo; Stephen D Nimer; M Lee; Thomas R Belin; Richard Champlin
Long-term outcome of high-dose cytarabine-based consolidation chemotherapy for adults with acute myelogenous leukemia.
Blood 1992;80(12):2977-82.
1992: J Nichols; Stephen D Nimer
Transcription factors, translocations, and leukemia.
Blood 1992;80(12):2953-63.
1992: Kathleen M Sakamoto; Stephen D Nimer; Joseph D Rosenblatt; Judith C Gasson
HTLV-I and HTLV-II tax trans-activate the human EGR-1 promoter through different cis-acting sequences.
Oncogene 1992;7(11):2125-30.
1992: Stephen D Nimer
The use of colony-stimulating factors in primary hematologic disorders.
Cancer 1992;70(4 Suppl):921-7.
1992: Gary J Schiller; James L Gajewski; Stephen D Nimer; Mary Territo; W Ho; M Lee; Richard Champlin
A randomized study of intermediate versus conventional-dose cytarabine as intensive induction for acute myelogenous leukaemia.
British journal of haematology 1992;81(2):170-7.
1992: Charles L Sawyers; David W Golde; S Quan; Stephen D Nimer
Production of granulocyte-macrophage colony-stimulating factor in two patients with lung cancer, leukocytosis, and eosinophilia.
Cancer 1992;69(6):1342-6.
1992: Gary J Schiller; Stephen D Nimer; Mary Territo; W G Ho; R E Champlin; James L Gajewski
Bone marrow transplantation versus high-dose cytarabine-based consolidation chemotherapy for acute myelogenous leukemia in first remission.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1992;10(1):41-6.
1992: Richard Champlin; Sergio Giralt; D Przepiorka; W Ho; K Lee; James L Gajewski; Stephen D Nimer; B Andersson; R Wallerstein; C Ippolito
Selective depletion of CD8-positive T-lymphocytes for allogeneic bone marrow transplantation: engraftment, graft-versus-host disease and graft-versus leukemia.
Progress in clinical and biological research 1992;377():385-94; discussion 395-8.
1991: Stephen D Nimer
Tax responsiveness of the GM-CSF promoter is mediated by mitogen-inducible sequences other than kappa B.
The New biologist 1991;3(10):997-1004.
1991: Stephen D Nimer; David W Golde; K Kwan; K Lee; Steven S Clark; Richard Champlin
In vitro production of granulocyte-macrophage colony-stimulating factor in aplastic anemia: possible mechanisms of action of antithymocyte globulin.
Blood 1991;78(1):163-8.
1991: Gary J Schiller; Stephen D Nimer; James L Gajewski; D W Golde
Abdominal presentation of varicella-zoster infection in recipients of allogeneic bone marrow transplantation.
Bone marrow transplantation 1991;7(6):489-91.
1991: Allen R Nissenson; Stephen D Nimer; D L Wolcott
Recombinant human erythropoietin and renal anemia: molecular biology, clinical efficacy, and nervous system effects.
Annals of internal medicine 1991;114(5):402-16.
1991: Richard Champlin; J Jansen; W Ho; James L Gajewski; Stephen D Nimer; K Lee; Mary Territo; D Winston; Guido Tricot; T Reichert
Retention of graft-versus-leukemia using selective depletion of CD8-positive T lymphocytes for prevention of graft-versus-host disease following bone marrow transplantation for chronic myelogenous leukemia.
Transplantation proceedings 1991;23(1 Pt 2):1695-6.
1990: Stephen D Nimer; J Fraser; J Richards; M Lynch; Judith C Gasson
The repeated sequence CATT(A/T) is required for granulocyte-macrophage colony-stimulating factor promoter activity.
Molecular and cellular biology 1990;10(11):6084-8.
1990: Richard Champlin; James L Gajewski; Stephen D Nimer; S Vollset; Elliot M Landaw; D Winston; Gary J Schiller; W Ho
Postremission chemotherapy for adults with acute myelogenous leukemia: improved survival with high-dose cytarabine and daunorubicin consolidation treatment.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1990;8(7):1199-206.
1990: Stephen D Nimer; A L Milewicz; R E Champlin; Ronald W Busuttil
Successful treatment of hepatic venoocclusive disease in a bone marrow transplant patient with orthotopic liver transplantation.
Transplantation 1990;49(4):819-21.
1990: R E Champlin; W G Ho; Stephen D Nimer; J G Gajewski; Michael T Selch; M Burnison; G Holley; P Yam; Lawrence D Petz; Drew J Winston
Bone marrow transplantation for severe aplastic anemia. Effect of a preparative regimen of cyclophosphamide-low-dose total-lymphoid irradiation and posttransplant cyclosporine-methotrexate therapy.
Transplantation 1990;49(4):720-4.
1990: F Naeim; Richard Champlin; Stephen D Nimer
Bone marrow changes in patients with refractory aplastic anemia treated by recombinant GM-CSF.
Hematologic pathology 1990;4(2):79-85.
1990: Judith C Gasson; John K Fraser; Stephen D Nimer
Human granulocyte-macrophage colony-stimulating factor (GM-CSF): regulation of expression.
Progress in clinical and biological research 1990;338():27-41.
1990: R E Champlin; Stephen D Nimer; D Oette; David W Golde
Effects of recombinant human granulocyte-macrophage colony-stimulating factor as treatment for aplastic anemia and agranulocytosis.
Progress in clinical and biological research 1990;338():143-50.
1990: Stephen D Nimer; R E Champlin
Therapeutic use of hematopoietic growth factors in bone marrow transplantation.
Cancer treatment and research 1990;50():141-64.
1989: James L Gajewski; W G Ho; Stephen D Nimer; K F Hirji; L Gekelman; A D Jacobs; R E Champlin
Efficacy of intensive chemotherapy for acute myelogenous leukemia associated with a preleukemic syndrome.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1989;7(11):1637-45.
1989: Stephen D Nimer; M J Gates; H Phillip Koeffler; Judith C Gasson
Multiple mechanisms control the expression of granulocyte-macrophage colony-stimulating factor by human fibroblasts.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(7):2374-7.
1989: Stephen D Nimer; Judith C Gasson; K Hu; I Smalberg; J L Williams; Irvin S Y Chen; Joseph D Rosenblatt
Activation of the GM-CSF promoter by HTLV-I and -II tax proteins.
Oncogene 1989;4(6):671-6.
1989: R E Champlin; Stephen D Nimer; P Ireland; D H Oette; David W Golde
Treatment of refractory aplastic anemia with recombinant human granulocyte-macrophage-colony-stimulating factor.
Blood 1989;73(3):694-9.
1988: Stephen D Nimer; R E Champlin; David W Golde
Serum cholesterol-lowering activity of granulocyte-macrophage colony-stimulating factor.
JAMA : the journal of the American Medical Association 1988;260(22):3297-300.
1988: Stephen D Nimer; E A Morita; M J Martis; W Wachsman; Judith C Gasson
Characterization of the human granulocyte-macrophage colony-stimulating factor promoter region by genetic analysis: correlation with DNase I footprinting.
Molecular and cellular biology 1988;8(5):1979-84.
1988: Stephen D Nimer; Judith C Gasson; J F DiPersio
The expression and target cell specificity of human granulocyte-macrophage colony-stimulating factor.
The Year in immunology 1988;3():144-51.
1987: Stephen D Nimer; David W Golde
The 5q- abnormality.
Blood 1987;70(6):1705-12.
1986: J Y Chan; Dennis J Slamon; Stephen D Nimer; D W Golde; J C Gasson
Regulation of expression of human granulocyte/macrophage colony-stimulating factor.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(22):8669-73.