FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Raymond Nims

Research Profile

Living Beings

Chemicals & Drugs

Physiology

Anatomy

Livers

Concepts & Ideas

Co-author Network

Publications

TOP 3
Wendell E Landin; Greg C Mun; Raymond W Nims; John W Harbell
Use of the cytosensor microphysiometer to predict results of a 21-day cumulative irritation patch test in humans.
Keiko Inami; Raymond W Nims; Aloka Srinivasan; Michael L Citro; Joseph E Saavedra; Arthur I Cederbaum; Larry K Keefer
Metabolism of a liver-selective nitric oxide-releasing agent, V-PYRRO/NO, by human microsomal cytochromes P450.
Katrina M Miranda; Raymond W Nims; Douglas D Thomas; Michael G Espey; Deborah Citrin; Michael D Bartberger; Nazareno Paolocci; Jon M Fukuto; Martin Feelisch; David A Wink
Comparison of the reactivity of nitric oxide and nitroxyl with heme proteins. A chemical discussion of the differential biological effects of these redox related products of NOS.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Raymond Nims (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2007: Wendell E Landin; Greg C Mun; Raymond W Nims; John W Harbell
Use of the cytosensor microphysiometer to predict results of a 21-day cumulative irritation patch test in humans.
Toxicology in vitro : an international journal published in association with BIBRA 2007;21(6):1165-73.
2006: Keiko Inami; Raymond W Nims; Aloka Srinivasan; Michael L Citro; Joseph E Saavedra; Arthur I Cederbaum; Larry K Keefer
Metabolism of a liver-selective nitric oxide-releasing agent, V-PYRRO/NO, by human microsomal cytochromes P450.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2006;14(4):309-15.
2003: Katrina M Miranda; Raymond W Nims; Douglas D Thomas; Michael G Espey; Deborah Citrin; Michael D Bartberger; Nazareno Paolocci; Jon M Fukuto; Martin Feelisch; David A Wink
Comparison of the reactivity of nitric oxide and nitroxyl with heme proteins. A chemical discussion of the differential biological effects of these redox related products of NOS.
Journal of inorganic biochemistry 2003;93(1-2):52-60.
2002: Sherman F Stinson; TL House; Chris Bramhall; Joseph E Saavedra; Larry K Keefer; Raymond W Nims
Plasma pharmacokinetics of a liver-selective nitric oxide-donating diazeniumdiolate in the male C57BL/6 mouse.
Xenobiotica; the fate of foreign compounds in biological systems 2002;32(4):339-47.
2001: Bhalchandra A Diwan; John R Henneman; Raymond W Nims
Enhancement of N-nitrosodiethylamine-initiated hepatocarcinogenesis by phentoin in male F344/NCr rats at a dose causing maximal induction of CYP2B.
International journal of toxicology 2001;20(2):81-7.
1998: C R Jones; R A Lubet; John R Henneman; Raymond W Nims
Dose-response relationships for cytochrome P450 induction by phenobarbital in the cotton rat (Sigmodon hispidus).
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology 1998;121(1-3):197-203.
1998: Stephen D Fox; John M Roman; Haleem J Issaq; Raymond W Nims
Metabolic conversion of 1,1-dichloro-2,2-bis(p-chlorophenyl)ethane (DDD) to 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE) in the male F344/NCr Rat.
Archives of environmental contamination and toxicology 1998;35(1):104-8.
1998: Raymond W Nims; R A Lubet; Stephen D Fox; C R Jones; P E Thomas; AB Reddy; Thomas A Kocarek
Comparative pharmacodynamics of CYP2B induction by DDT, DDE, and DDD in male rat liver and cultured rat hepatocytes.
Journal of toxicology and environmental health. Part A 1998;53(6):455-77.
1998: Raymond W Nims; A P Shoemaker; M A Bauernschub; L J Rec; John W Harbell
Sensitivity of isoenzyme analysis for the detection of interspecies cell line cross-contamination.
In vitro cellular & developmental biology. Animal 1998;34(1):35-9.
1997: Raymond W Nims; Russell A Prough; C R Jones; D L Stockus; K H Dragnev; P E Thomas; R A Lubet
In vivo induction and in vitro inhibition of hepatic cytochrome P450 activity by the benzodiazepine anticonvulsants clonazepam and diazepam.
Drug metabolism and disposition: the biological fate of chemicals 1997;25(6):750-6.
1996: E T Hellriegel; George Matwyshyn; P Fei; K H Dragnev; Raymond W Nims; Ronald A Lubet; Ah-Ng Tony Kong
Regulation of gene expression of various phase I and phase II drug-metabolizing enzymes by tamoxifen in rat liver.
Biochemical pharmacology 1996;52(10):1561-8.
1996: John A Cook; S Y Kim; D Teague; Murali K Cherukuri; R Pacelli; James B Mitchell; Y Vodovotz; Raymond W Nims; D Christodoulou; AM Miles; Matthew B Grisham; David A Wink
Convenient colorimetric and fluorometric assays for S-nitrosothiols.
Analytical biochemistry 1996;238(2):150-8.
1996: Larry K Keefer; Raymond W Nims; K M Davies; David A Wink
"NONOates" (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: convenient nitric oxide dosage forms.
Methods in enzymology 1996;268():281-93.
1996: David A Wink; Matthew B Grisham; AM Miles; Raymond W Nims; Murali K Cherukuri; R Pacelli; D Teague; C M Poore; John A Cook; P C Ford
Determination of selectivity of reactive nitrogen oxide species for various substrates.
Methods in enzymology 1996;268():120-30.
1996: Raymond W Nims; J C Cook; Murali K Cherukuri; D Christodoulou; C M Poore; AM Miles; Matthew B Grisham; David A Wink
Colorimetric assays for nitric oxide and nitrogen oxide species formed from nitric oxide stock solutions and donor compounds.
Methods in enzymology 1996;268():93-105.
1996: David A Wink; I Hanbauer; M B Grisham; F Laval; Raymond W Nims; J Laval; J Cook; R Pacelli; J Liebmann; M Krishna; P C Ford; J B Mitchell
Chemical biology of nitric oxide: regulation and protective and toxic mechanisms.
Current topics in cellular regulation 1996;34():159-87.
1996: Bhalchandra A Diwan; J R Henneman; Jerry M Rice; Raymond W Nims
Enhancement of thyroid and hepatocarcinogenesis by 1,4-bis[2-(3,5- dichloropyridyloxy)]benzene in rats at doses that cause maximal induction of CYP2B.
Carcinogenesis 1996;17(1):37-43.
1995: K H Dragnev; Raymond W Nims; Ronald A Lubet
The chemopreventive agent diallyl sulfide. A structurally atypical phenobarbital-type inducer.
Biochemical pharmacology 1995;50(12):2099-104.
1995: K H Dragnev; Raymond W Nims; Stephen D Fox; R Lindahl; Ronald A Lubet
Relative potencies of induction of hepatic drug-metabolizing enzyme genes by individual PCB congeners.
Toxicology and applied pharmacology 1995;132(2):334-42.
1994: Raymond W Nims; Jaspreet S Sidhu; P E Thomas; D W Mellini; V C Nelson; C J Omiecinski; Ronald A Lubet
Absence of enantioselectivity in the pharmacodynamics of P450 2B induction by 5-ethyl-5-phenylhydantoin in the male rat liver or in cultured rat hepatocytes.
Journal of biochemical toxicology 1994;9(6):279-88.
1994: Raymond W Nims; Stephen D Fox; Haleem J Issaq; Ronald A Lubet
Accumulation and persistence of individual polychlorinated biphenyl congeners in liver, blood, and adipose tissue of rats following dietary exposure to Aroclor 1254.
Archives of environmental contamination and toxicology 1994;27(4):513-20.
1994: Raymond W Nims; Ronald A Lubet; B A Diwan; D W Mellini; W E Utermahlen; P E Thomas
Hepatic cytochrome P450 2B induction by ethyl/phenyl-substituted congeners of phenobarbital in the B6C3F1 mouse.
Journal of biochemical toxicology 1994;9(5):269-78.
1994: David A Wink; C B Wink; Raymond W Nims; P C Ford
Oxidizing intermediates generated in the Fenton reagent: kinetic arguments against the intermediacy of the hydroxyl radical.
Environmental health perspectives 1994;102 Suppl 3():11-5.
1994: David A Wink; Raymond W Nims; Joseph E Saavedra; W E Utermahlen; P C Ford
The Fenton oxidation mechanism: reactivities of biologically relevant substrates with two oxidizing intermediates differ from those predicted for the hydroxyl radical.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(14):6604-8.
1994: Raymond W Nims; R M McClain; P S Manchand; P S Belica; P E Thomas; D W Mellini; W E Utermahlen; Ronald A Lubet
Comparative pharmacodynamics of hepatic cytochrome P450 2B induction by 5,5-diphenyl- and 5,5-diethyl-substituted barbiturates and hydantoins in the male F344/NCr rat.
The Journal of pharmacology and experimental therapeutics 1994;270(1):348-55.
1994: David A Wink; Raymond W Nims; J F Darbyshire; D Christodoulou; I Hanbauer; G W Cox; F Laval; J Laval; John A Cook; Murali K Cherukuri
Reaction kinetics for nitrosation of cysteine and glutathione in aerobic nitric oxide solutions at neutral pH. Insights into the fate and physiological effects of intermediates generated in the NO/O2 reaction.
Chemical research in toxicology 1994;7(4):519-25.
1994: J R Henneman; Stephen D Fox; Ronald A Lubet; J M Ward; Raymond W Nims
Induction of cytochrome P-450 in Sigmodon hispidus (cotton rats) exposed to dietary Aroclor 1254.
Journal of toxicology and environmental health 1994;41(3):369-86.
1994: K H Dragnev; L E Beebe; C R Jones; Stephen D Fox; P E Thomas; Raymond W Nims; Ronald A Lubet
Subchronic dietary exposure to Aroclor 1254 in rats: accumulation of PCBs in liver, blood, and adipose tissue and its relationship to induction of various hepatic drug-metabolizing enzymes.
Toxicology and applied pharmacology 1994;125(1):111-22.
1993: Raymond W Nims; P R Sinclair; J F Sinclair; K H Dragnev; C R Jones; D W Mellini; P E Thomas; Ronald A Lubet
Dose-response relationships for the induction of P450 2B by 1,4-bis[2-(3,5-dichloropyridyloxy)]benzne (TCPOBOP) in rat and cultured rat hepatocytes.
Xenobiotica; the fate of foreign compounds in biological systems 1993;23(12):1411-26.
1993: Bhalchandra A Diwan; J R Henneman; Raymond W Nims; Jerry M Rice
Tumor promotion by an anticonvulsant agent, phenytoin, in mouse liver: correlation with CYP2B induction.
Carcinogenesis 1993;14(11):2227-31.
1993: P V Nerurkar; S S Park; P E Thomas; Raymond W Nims; Ronald A Lubet
Methoxyresorufin and benzyloxyresorufin: substrates preferentially metabolized by cytochromes P4501A2 and 2B, respectively, in the rat and mouse.
Biochemical pharmacology 1993;46(5):933-43.
1993: Raymond W Nims; P R Sinclair; J F Sinclair; P E Thomas; C R Jones; D W Mellini; J L Syi; Ronald A Lubet
Pharmacodynamics of cytochrome P450 2B induction by phenobarbital, 5-ethyl-5-phenylhydantoin, and 5-ethyl-5-phenyloxazolidinedione in the male rat liver or in cultured rat hepatocytes.
Chemical research in toxicology 1993;6(2):188-96.
1993: Raymond W Nims; J L Syi; David A Wink; V C Nelson; P E Thomas; C R Jones; Bhalchandra A Diwan; Larry K Keefer; Jerry M Rice; Ronald A Lubet
Hepatic cytochrome P450 2B-type induction by ethyl/phenyl-substituted congeners of phenobarbital in the rat.
Chemical research in toxicology 1993;6(2):180-7.
1993: Raymond W Nims; Ronald A Lubet; C R Jones; D W Mellini; P E Thomas
Comparative pharmacodynamics of CYP2B induction by phenobarbital in the male and female F344/NCr rat.
Biochemical pharmacology 1993;45(2):521-6.
1993: David A Wink; J F Darbyshire; Raymond W Nims; Joseph E Saavedra; P C Ford
Reactions of the bioregulatory agent nitric oxide in oxygenated aqueous media: determination of the kinetics for oxidation and nitrosation by intermediates generated in the NO/O2 reaction.
Chemical research in toxicology 1993;6(1):23-7.
1993: David A Wink; Yoichi Osawa; J F Darbyshire; C R Jones; S C Eshenaur; Raymond W Nims
Inhibition of cytochromes P450 by nitric oxide and a nitric oxide-releasing agent.
Archives of biochemistry and biophysics 1993;300(1):115-23.
1992: Raymond W Nims; L E Beebe; K H Dragnev; P E Thomas; Stephen D Fox; Haleem J Issaq; C R Jones; Ronald A Lubet
Induction of hepatic CYP1A in male F344/NCr rats by dietary exposure to Aroclor 1254: examination of immunochemical, RNA, catalytic, and pharmacokinetic endpoints.
Environmental research 1992;59(2):447-66.
1992: Ronald A Lubet; Raymond W Nims; L E Beebe; Stephen D Fox; Haleem J Issaq; K McBee
Induction of hepatic CYP1A activity as a biomarker for environmental exposure to Aroclor 1254 in feral rodents.
Archives of environmental contamination and toxicology 1992;22(3):339-44.
1992: Ronald A Lubet; Raymond W Nims; K H Dragnev; C R Jones; Bhalchandra A Diwan; D E Devor; J M Ward; M S Miller; Jerry M Rice
A markedly diminished pleiotropic response to phenobarbital and structurally-related xenobiotics in Zucker rats in comparison with F344/NCr or DA rats.
Biochemical pharmacology 1992;43(5):1079-87.
1992: Ronald A Lubet; K H Dragnev; D P Chauhan; Raymond W Nims; Bhalchandra A Diwan; J M Ward; C R Jones; Jerry M Rice; M S Miller
A pleiotropic response to phenobarbital-type enzyme inducers in the F344/NCr rat. Effects of chemicals of varied structure.
Biochemical pharmacology 1992;43(5):1067-78.
1992: Jerry M Rice; Bhalchandra A Diwan; J M Ward; Raymond W Nims; Ronald A Lubet
Phenobarbital and related compounds: approaches to interspecies extrapolation.
Progress in clinical and biological research 1992;374():231-49.
1992: Bhalchandra A Diwan; Raymond W Nims; J R Henneman; J M Ward; Ronald A Lubet; Jerry M Rice
Effects of the oxazolidinedione anticonvulsants trimethadione and dimethadione and the barbiturate homolog 5,5-dimethylbarbituric acid on N-nitrosodiethylamine-initiated renal and hepatic carcinogenesis in the F344/NCr rat.
Archives of toxicology 1992;66(6):413-22.
1991: David A Wink; Raymond W Nims; M F Desrosiers; P C Ford; Larry K Keefer
A kinetic investigation of intermediates formed during the Fenton reagent mediated degradation of N-nitrosodimethylamine: evidence for an oxidative pathway not involving hydroxyl radical.
Chemical research in toxicology 1991;4(5):510-2.
1991: Ronald A Lubet; C R Jones; D L Stockus; Stephen D Fox; Raymond W Nims
Induction of cytochrome P450 and other drug metabolizing enzymes in rat liver following dietary exposure to Aroclor 1254.
Toxicology and applied pharmacology 1991;108(2):355-65.
1991: E von Hofe; I Schmerold; Raymond W Nims; Larry K Keefer; E J Reist; Paul Kleihues
Beta-deuteration of N-nitrosoethylmethylamine causes a shift in DNA methylation from rat liver to esophagus.
Carcinogenesis 1991;12(4):545-9.
1991: A J Streeter; Raymond W Nims; P R Sheffels; Larry K Keefer
Denitrosation of N-nitrosodimethylamine in the rat in vivo.
Advances in experimental medicine and biology 1991;283():371-5.
1991: A J Streeter; Raymond W Nims; Larry K Keefer
Toxicokinetic studies of N-nitrosamine carcinogenesis.
IARC scientific publications 1991;(105):362-5.
1990: A J Streeter; Raymond W Nims; P R Sheffels; Joseph A Hrabie; L Ohannesian; Y H Heur; B A Mico; Larry K Keefer
Deuterium isotope effect on the toxicokinetics of monomethylamine in the rat.
Drug metabolism and disposition: the biological fate of chemicals 1990;18(4):447-52.
1990: Ronald A Lubet; F P Guengerich; Raymond W Nims
The induction of alkoxyresorufin metabolism: a potential indicator of environmental contamination.
Archives of environmental contamination and toxicology 1990;19(2):157-63.
1990: A J Streeter; Raymond W Nims; P R Sheffels; Y H Heur; Chung S Yang; B A Mico; C T Gombar; Larry K Keefer
Metabolic denitrosation of N-nitrosodimethylamine in vivo in the rat.
Cancer research 1990;50(4):1144-50.
1990: Ronald A Lubet; J L Syi; J O Nelson; Raymond W Nims
Induction of hepatic cytochrome P-450 mediated alkoxyresorufin O-dealkylase activities in different species by prototype P-450 inducers.
Chemico-biological interactions 1990;75(3):325-39.
1990: A J Streeter; Raymond W Nims; Lucy M Anderson; Y H Heur; E von Hofe; Paul Kleihues; V C Nelson; B A Mico; Larry K Keefer
Single-dose toxicokinetics of N-nitrosomethylethylamine and N-nitrosomethyl (2,2,2-trideuterioethyl)amine in the rat.
Archives of toxicology 1990;64(2):109-15.
1990: A J Streeter; Raymond W Nims; P P Wu; Daniel Logsdon
Toxicokinetics of N-nitrosodimethylamine in the Syrian golden hamster.
Archives of toxicology 1990;64(7):562-6.
1989: Bhalchandra A Diwan; Ronald A Lubet; Raymond W Nims; J E Klaunig; Christopher M Weghorst; J R Henneman; J M Ward; Jerry M Rice
Lack of promoting effect of clonazepam on the development of N-nitrosodiethylamine-initiated hepatocellular tumors in mice is correlated with its inability to inhibit cell-to-cell communication in mouse hepatocytes.
Carcinogenesis 1989;10(9):1719-24.
1989: Y H Heur; A J Streeter; Raymond W Nims; Larry K Keefer
The Fenton degradation as a nonenzymatic model for microsomal denitrosation of N-nitrosodimethylamine.
Chemical research in toxicology 1989;2(4):247-53.
1989: A J Streeter; Raymond W Nims; Joseph A Hrabie; Y H Heur; Larry K Keefer
Sex differences in the single-dose toxicokinetics of N-nitrosomethyl(2-hydroxyethyl)amine in the rat.
Cancer research 1989;49(7):1783-9.
1987: Raymond W Nims; D E Devor; J R Henneman; Ronald A Lubet
Induction of alkoxyresorufin O-dealkylases, epoxide hydrolase, and liver weight gain: correlation with liver tumor-promoting potential in a series of barbiturates.
Carcinogenesis 1987;8(1):67-71.