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Yoshifumi Ninomiya

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Anatomy

Chemicals & Drugs

Procedures

Physiology

Gene Expression Regulation, Developmental

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Ryusuke Momota; Ichiro Naito; Masahiro Narasaki; Yoshifumi Ninomiya; Takaaki Komiyama; Aiji Ohtsuka
Drosophila type XV/XVIII collagen mutants manifest integrin mediated mitochondrial dysfunction, which is improved by cyclosporin A and losartan.
Kotaro Hirashima; Yumi Honda; Ken-Ichi Iyama; Yoshifumi Ninomiya; Yoshikazu Sado; Hiroshi Takamori; Masayuki Watanabe; Yoshifumi Baba; Toru Beppu; Hideo Baba
Differential expression of basement membrane type IV collagen α2 and α6 chains as a prognostic factor in patients with extrahepatic bile duct carcinoma.
Masanari Obika; Hiroko Ogawa; Takashi Ohtsuki; Katsuyuki Takahashi; Junko Inagaki; Shozo Kusachi; Jiayi Li; Toru Miyoshi; Yoshifumi Ninomiya; Mehmet Cilek; Omer Faruk Hatipoglu; Satoshi Hirohata
Tumor growth inhibitory effect of ADAMTS1 is accompanied by the inhibition of tumor angiogenesis.

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2013: Ryusuke Momota; Ichiro Naito; Masahiro Narasaki; Yoshifumi Ninomiya; Takaaki Komiyama; Aiji Ohtsuka
Drosophila type XV/XVIII collagen mutants manifest integrin mediated mitochondrial dysfunction, which is improved by cyclosporin A and losartan.
The international journal of biochemistry & cell biology 2013;45(5):1003-11.
2013: Kotaro Hirashima; Yumi Honda; Ken-Ichi Iyama; Yoshifumi Ninomiya; Yoshikazu Sado; Hiroshi Takamori; Masayuki Watanabe; Yoshifumi Baba; Toru Beppu; Hideo Baba
Differential expression of basement membrane type IV collagen α2 and α6 chains as a prognostic factor in patients with extrahepatic bile duct carcinoma.
Journal of surgical oncology 2013;107(4):402-7.
2012: Masanari Obika; Hiroko Ogawa; Takashi Ohtsuki; Katsuyuki Takahashi; Junko Inagaki; Shozo Kusachi; Jiayi Li; Toru Miyoshi; Yoshifumi Ninomiya; Mehmet Cilek; Omer Faruk Hatipoglu; Satoshi Hirohata
Tumor growth inhibitory effect of ADAMTS1 is accompanied by the inhibition of tumor angiogenesis.
Cancer science 2012;103(10):1889-97.
2012: Yoko Bekku; Maki Fuchigami; Shozo Kusachi; Ami Maehara; Markus Moser; Masaru Nakayama; Yoshifumi Ninomiya; Mai Saito; Toshitaka Oohashi
Bral2 is indispensable for the proper localization of brevican and the structural integrity of the perineuronal net in the brainstem and cerebellum.
The Journal of comparative neurology 2012;520(8):1721-36.
2012: Tomoko Kanazawa; Yoshifumi Ninomiya; Toshitaka Oohashi; Takayuki Furumatsu; Motomi Hachioji; Toshifumi Ozaki
Mechanical stretch enhances COL2A1 expression on chromatin by inducing SOX9 nuclear translocalization in inner meniscus cells.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2012;30(3):468-74.
2011: Toru Miyoshi; Yoshifumi Ninomiya; Hiroko Ogawa; Kosuke Sakane; Shinichi Usui; Masayuki Doi; Satoshi Hirohata; Reishi Izumi; Shigeshi Kamikawa; Shozo Kusachi
Olmesartan reduces arterial stiffness and serum adipocyte fatty acid-binding protein in hypertensive patients.
Heart and vessels 2011;26(4):408-13.
2011: Ryusuke Momota; Ichiro Naito; Yoshifumi Ninomiya; Aiji Ohtsuka
Drosophila type XV/XVIII collagen, Mp, is involved in Wingless distribution.
Matrix biology : journal of the International Society for Matrix Biology 2011;30(4):258-66.
2011: Kenji Saito; Tomoko Yonezawa; Jun Minaguchi; Masae Kurosaki; Shiho Suetsugu; Ai Nakajima; Hiroyuki Nomoto; Yuki Morizane; Yoshikazu Sado; Manabu Sugimoto; Shozo Kusachi; Yoshifumi Ninomiya
Distribution of α(IV) collagen chains in the ocular anterior segments of adult mice.
Connective tissue research 2011;52(2):147-56.
2011: Toshitaka Oohashi; Ichiro Naito; Yasuyoshi Ueki; Tomoki Yamatsuji; Rattiya Permpoon; Noriaki Tanaka; Yoshio Naomoto; Yoshifumi Ninomiya
Clonal overgrowth of esophageal smooth muscle cells in diffuse leiomyomatosis-Alport syndrome caused by partial deletion in COL4A5 and COL4A6 genes.
Matrix biology : journal of the International Society for Matrix Biology 2011;30(1):3-8.
2011: Mehmet Cilek; Satoshi Hirohata; Omer Faruk Hatipoglu; Hiroko Ogawa; Toru Miyoshi; Junko Inagaki; Takashi Ohtsuki; Hiroshi Harada; Shigeshi Kamikawa; Shozo Kusachi; Yoshifumi Ninomiya
AHR, a novel acute hypoxia-response sequence, drives reporter gene expression under hypoxia in vitro and in vivo.
Cell biology international 2011;35(1):1-8.
2010: Mutsumi Iwamoto; Satoshi Hirohata; Hiroko Ogawa; Takashi Ohtsuki; Ryoko Shinohata; Toru Miyoshi; Omer Faruk Hatipoglu; Shozo Kusachi; Kazuhide Yamamoto; Yoshifumi Ninomiya
Connective tissue growth factor induction in a pressure-overloaded heart ameliorated by the angiotensin II type 1 receptor blocker olmesartan.
Hypertension research : official journal of the Japanese Society of Hypertension 2010;33(12):1305-11.
2010: Toru Miyoshi; Go Onoue; Atsushi Hirohata; Satoshi Hirohata; Shinichi Usui; Kazuyoshi Hina; Hiroshi Kawamura; Masayuki Doi; Kengo Fukushima Kusano; Shozo Kusachi; Yoshifumi Ninomiya
Serum adipocyte fatty acid-binding protein is independently associated with coronary atherosclerotic burden measured by intravascular ultrasound.
Atherosclerosis 2010;211(1):164-9.
2010: Tomoko Yonezawa; Shunji Hattori; Junko Inagaki; Masae Kurosaki; Tomoyuki Takigawa; Satoshi Hirohata; Toru Miyoshi; Yoshifumi Ninomiya
Type IV collagen induces expression of thrombospondin-1 that is mediated by integrin alpha1beta1 in astrocytes.
Glia 2010;58(7):755-67.
2010: Tomoyuki Takigawa; Tomoko Yonezawa; Teruhito Yoshitaka; Jun Minaguchi; Masae Kurosaki; Masato Tanaka; Yoshikazu Sado; Aiji Ohtsuka; Toshifumi Ozaki; Yoshifumi Ninomiya
Separation of the perivascular basement membrane provides a conduit for inflammatory cells in a mouse spinal cord injury model.
Journal of neurotrauma 2010;27(4):739-51.
2010: Toru Miyoshi; Masayuki Doi; Satoshi Hirohata; Kosuke Sakane; Shigeshi Kamikawa; Tomoki Kitawaki; Youko Kaji; Kengo Fukushima Kusano; Yoshifumi Ninomiya; Shozo Kusachi
Cardio-ankle vascular index is independently associated with the severity of coronary atherosclerosis and left ventricular function in patients with ischemic heart disease.
Journal of atherosclerosis and thrombosis 2010;17(3):249-58.
2010: Yoko Bekku; Lýdia Vargová; Yoshinobu Goto; Ivan Vorísek; Lesia Dmytrenko; Masahiro Narasaki; Aiji Ohtsuka; Reinhard Fässler; Yoshifumi Ninomiya; Eva Syková; Toshitaka Oohashi
Bral1: its role in diffusion barrier formation and conduction velocity in the CNS.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(8):3113-23.
2010: Tomoko Kawabata; Keiichiro Nishida; Koji Takasugi; Hiroko Ogawa; Kenei Sada; Yasutaka Kadota; Junko Inagaki; Satoshi Hirohata; Yoshifumi Ninomiya; Hirofumi Makino
Increased activity and expression of histone deacetylase 1 in relation to tumor necrosis factor-alpha in synovial tissue of rheumatoid arthritis.
Arthritis research & therapy 2010;12(4):R133.
2009: Omer Faruk Hatipoglu; Satoshi Hirohata; Mehmet Cilek; Hiroko Ogawa; Toru Miyoshi; Masanari Obika; Kadir Demircan; Ryoko Shinohata; Shozo Kusachi; Yoshifumi Ninomiya
ADAMTS1 is a unique hypoxic early response gene expressed by endothelial cells.
The Journal of biological chemistry 2009;284(24):16325-33.
2009: Kadir Demircan; Esra Gunduz; Mehmet Gunduz; Levent Beder; Satoshi Hirohata; Hitoshi Nagatsuka; Beyhan Cengiz; Mehmet Cilek; Noboru Yamanaka; Kenji Shimizu; Yoshifumi Ninomiya
Increased mRNA expression of ADAMTS metalloproteinases in metastatic foci of head and neck cancer.
Head & neck 2009;31(6):793-801.
2009: Omer Faruk Hatipoglu; Satoshi Hirohata; Kursat Oguz Yaykasli; Mehmet Cilek; Kadir Demircan; Ryoko Shinohata; Tomoko Yonezawa; Toshitaka Oohashi; Shozo Kusachi; Yoshifumi Ninomiya
The 3'-untranslated region of ADAMTS1 regulates its mRNA stability.
Acta medica Okayama 2009;63(2):79-85.
2009: Yoko Bekku; Uwe Rauch; Yoshifumi Ninomiya; Toshitaka Oohashi
Brevican distinctively assembles extracellular components at the large diameter nodes of Ranvier in the CNS.
Journal of neurochemistry 2009;108(5):1266-76.
2009: Kursat Oguz Yaykasli; Toshitaka Oohashi; Satoshi Hirohata; Omer Faruk Hatipoglu; Kiichi Inagawa; Kadir Demircan; Yoshifumi Ninomiya
ADAMTS9 activation by interleukin 1 beta via NFATc1 in OUMS-27 chondrosarcoma cells and in human chondrocytes.
Molecular and cellular biochemistry 2009;323(1-2):69-79.
2009: Kanae Kumagishi; Keiichiro Nishida; Tomoichiro Yamaai; Ryusuke Momota; Shigeru Miyaki; Satoshi Hirohata; Ichiro Naito; Hiroshi Asahara; Yoshifumi Ninomiya; Aiji Ohtsuka
A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAMTS9) expression by chondrocytes during endochondral ossification.
Archives of histology and cytology 2009;72(3):175-85.
2008: Jun Minaguchi; Toshitaka Oohashi; Kiichi Inagawa; Aiji Ohtsuka; Yoshifumi Ninomiya
Transvascular accumulation of Sialyl Lewis X conjugated liposome in inflamed joints of collagen antibody-induced arthritic (CAIA) mice.
Archives of histology and cytology 2008;71(3):195-203.
2008: Noriko Hinenoya; Ichiro Naito; Ryusuke Momota; Yoshikazu Sado; Kanae Kumagishi; Yoshifumi Ninomiya; Aiji Ohtsuka
Type IV collagen alpha chains of the basement membrane in the rat bronchioalveolar transitional segment.
Archives of histology and cytology 2008;71(3):185-94.
2008: Jeong Suk Kang; Yasuhiko Kawakami; Yoko Bekku; Yoshifumi Ninomiya; Juan Carlos Izpisúa Belmonte; Toshitaka Oohashi
Molecular cloning and developmental expression of a hyaluronan and proteoglycan link protein gene, crtl1/hapln1, in zebrafish.
Zoological science 2008;25(9):912-8.
2008: Tetsushi Seitou; Masaaki Murakami; Issei Komatsubara; Hiroshi Kawamura; Keizo Yamamoto; Kazuyoshi Hina; Satoshi Hirohata; Ryoko Shinohata; Yoshifumi Ninomiya; Shozo Kusachi
Higher incidence and serum levels of minor cardiac biomarker elevation in sirolimus-eluting stent (Cypher) than bare metal stent implantations.
Coronary artery disease 2008;19(2):63-9.
2008: Yoshifumi Baba; Ken-Ichi Iyama; Koei Ikeda; Shinji Ishikawa; Naoko Hayashi; Nobutomo Miyanari; Yoshikazu Sado; Yoshifumi Ninomiya; Hideo Baba
The expression of type IV collagen alpha6 chain is related to the prognosis in patients with esophageal squamous cell carcinoma.
Annals of surgical oncology 2008;15(2):555-65.
2008: H Manabe; Y Nasu; T Komiyama; Takayuki Furumatsu; A Kitamura; S Miyazawa; Yoshifumi Ninomiya; T Ozaki; Hiroshi Asahara; Keiichiro Nishida
Inhibition of histone deacetylase down-regulates the expression of hypoxia-induced vascular endothelial growth factor by rheumatoid synovial fibroblasts.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2008;57(1):4-10.
2007: Hiroyuki Sato; Ichiro Naito; Ryusuke Momota; Yoshio Naomoto; Tomoki Yamatsuji; Yoshikazu Sado; Yoshifumi Ninomiya; Aiji Ohtsuka
The differential distribution of type IV collagen alpha chains in the subepithelial basement membrane of the human alimentary canal.
Archives of histology and cytology 2007;70(5):313-23.
2007: Haruko Hasegawa; Ichiro Naito; Kazuyo Nakano; Ryusuke Momota; Keiichiro Nishida; Takehito Taguchi; Yoshikazu Sado; Yoshifumi Ninomiya; Aiji Ohtsuka
The distributions of type IV collagen alpha chains in basement membranes of human epidermis and skin appendages.
Archives of histology and cytology 2007;70(4):255-65.
2007: Kazuyo Nakano; Ichiro Naito; Ryusuke Momota; Yoshikazu Sado; Haruko Hasegawa; Yoshifumi Ninomiya; Aiji Ohtsuka
The distribution of type IV collagen alpha chains in the mouse ovary and its correlation with follicular development.
Archives of histology and cytology 2007;70(4):243-53.
2007: Yoshifumi Baba; Ken-Ichi Iyama; Koei Ikeda; Shinji Ishikawa; Naoko Hayashi; Nobutomo Miyanari; Yumi Honda; Yoshikazu Sado; Yoshifumi Ninomiya; Hideo Baba
Differential expression of basement membrane type IV collagen alpha chains in gastric intramucosal neoplastic lesions.
Journal of gastroenterology 2007;42(11):874-80.
2006: Scott Harvey; Julie Perry; Keqin Zheng; Dilys Chen; Yoshikazu Sado; Barbara Jefferson; Yoshifumi Ninomiya; Robert Jacobs; Billy G Hudson; Paul S Thorner
Sequential expression of type IV collagen networks: testis as a model and relevance to spermatogenesis.
The American journal of pathology 2006;168(5):1587-97.
2006: Koei Ikeda; Ken-Ichi Iyama; Nobuyuki Ishikawa; Hiroshi Egami; Mitsuyoshi Nakao; Yoshikazu Sado; Yoshifumi Ninomiya; Hideo Baba
Loss of expression of type IV collagen alpha5 and alpha6 chains in colorectal cancer associated with the hypermethylation of their promoter region.
The American journal of pathology 2006;168(3):856-65.
2005: Keqin Zheng; Julie Perry; Scott Harvey; Yoshikazu Sado; Yoshifumi Ninomiya; Barbara Jefferson; Robert Jacobs; Billy G Hudson; Paul S Thorner
Regulation of collagen type IV genes is organ-specific: evidence from a canine model of Alport syndrome.
Kidney international 2005;68(5):2121-30.
2005: Tomoaki Yoshino; Hideaki Sumiyoshi; Toshitaka Shin; Noritaka Matsuo; Yutaka Inagaki; Yoshifumi Ninomiya; Hidekatsu Yoshioka
Multiple proteins are involved in the protein-DNA complex in the proximal promoter of the human alpha1(III) collagen gene (COL3A1).
Biochimica et biophysica acta 2005;1729(2):94-104.
2005: Zheng-Nan Shen; Keiichiro Nishida; Hideyuki Doi; Toshitaka Oohashi; Satoshi Hirohata; Toshifumi Ozaki; Aki Yoshida; Yoshifumi Ninomiya; Hajime Inoue
Suppression of chondrosarcoma cells by 15-deoxy-Delta 12,14-prostaglandin J2 is associated with altered expression of Bax/Bcl-xL and p21.
Biochemical and biophysical research communications 2005;328(2):375-82.
2004: Toshitaka Oohashi; Yoko Bekku; Yoshifumi Ninomiya
[Bral1, Bral2: the novel brain specific-hyaluronan and protoglycan link protein genes].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2004;49(15 Suppl):2354-61.
2004: Hiroko Ogawa; Toshitaka Oohashi; Masataka Sata; Yoko Bekku; Satoshi Hirohata; Keigo Nakamura; Tomoko Yonezawa; Shozo Kusachi; Yasushi Shiratori; Yoshifumi Ninomiya
Lp3/Hapln3, a novel link protein that co-localizes with versican and is coordinately up-regulated by platelet-derived growth factor in arterial smooth muscle cells.
Matrix biology : journal of the International Society for Matrix Biology 2004;23(5):287-98.
2004: Oliver Gross; Bogdan Beirowski; Scott Harvey; Catherine McFadden; Dilys Chen; Stephanie Tam; Paul S Thorner; Neil Smyth; Klaus Addicks; Wilhelm Bloch; Yoshifumi Ninomiya; Yoshikazu Sado; Manfred Weber; Wolfgang F Vogel
DDR1-deficient mice show localized subepithelial GBM thickening with focal loss of slit diaphragms and proteinuria.
Kidney international 2004;66(1):102-11.
2004: Shuji Misumi; Ken-Ichi Iyama; Yumi Honda; Takao Kitano; Yoshikazu Sado; Yoshifumi Ninomiya; Masanori Shinohara
Differential expression of basement membrane type-IV collagen alpha1, alpha2, alpha5 and alpha6 chains among the histological subtypes of adenoid cystic carcinoma.
Virchows Archiv : an international journal of pathology 2004;445(1):54-62.
2004: Shuichi Hirano; Tomoko Yonezawa; Haruko Hasegawa; Shunji Hattori; Nicholas S Greenhill; Paul F Davis; E Helene Sage; Yoshifumi Ninomiya
Astrocytes express type VIII collagen during the repair process of brain cold injury.
Biochemical and biophysical research communications 2004;317(2):437-43.
2004: Jeong Suk Kang; Toshitaka Oohashi; Yasuhiko Kawakami; Yoko Bekku; Juan Carlos Izpisúa Belmonte; Yoshifumi Ninomiya
Characterization of dermacan, a novel zebrafish lectican gene, expressed in dermal bones.
Mechanisms of development 2004;121(3):301-12.
2003: Tomoko Yonezawa; Aiji Ohtsuka; Teruhito Yoshitaka; Shuichi Hirano; Hiroyuki Nomoto; Kiyotaka Yamamoto; Yoshifumi Ninomiya
Limitrin, a novel immunoglobulin superfamily protein localized to glia limitans formed by astrocyte endfeet.
Glia 2003;44(3):190-204.
2003: Yoko Bekku; Wei-Dong Su; Satoshi Hirakawa; Reinhard Fässler; Aiji Ohtsuka; Jeong Suk Kang; Jennifer Sanders; Takuro Murakami; Yoshifumi Ninomiya; Toshitaka Oohashi
Molecular cloning of Bral2, a novel brain-specific link protein, and immunohistochemical colocalization with brevican in perineuronal nets.
Molecular and cellular neurosciences 2003;24(1):148-59.
2003: Hiroyuki Nomoto; Tomoko Yonezawa; Kouichi Itoh; Katsuhiko Ono; Kiyotaka Yamamoto; Toshitaka Oohashi; Fumio Shiraga; Hiroshi Ohtsuki; Yoshifumi Ninomiya
Molecular cloning of a novel transmembrane protein MOLT expressed by mature oligodendrocytes.
Journal of biochemistry 2003;134(2):231-8.
2003: Xiao-Hong Zhou; Oliver Brandau; Kang Feng; Toshitaka Oohashi; Yoshifumi Ninomiya; Uwe Rauch; Reinhard Fässler
The murine Ten-m/Odz genes show distinct but overlapping expression patterns during development and in adult brain.
Gene expression patterns : GEP 2003;3(4):397-405.
2003: Takayuki Furumatsu; Zheng-Nan Shen; Akira Kawai; Keiichiro Nishida; Hironori Manabe; Toshitaka Oohashi; Hajime Inoue; Yoshifumi Ninomiya
Vascular endothelial growth factor principally acts as the main angiogenic factor in the early stage of human osteoblastogenesis.
Journal of biochemistry 2003;133(5):633-9.
2003: Ichiro Naito; Yoshifumi Ninomiya; Shinsuke Nomura
Immunohistochemical diagnosis of Alport's syndrome in paraffin-embedded renal sections: antigen retrieval with autoclave heating.
Medical electron microscopy : official journal of the Clinical Electron Microscopy Society of Japan 2003;36(1):1-7.
2003: Scott Harvey; Keqin Zheng; Barbara Jefferson; Peter Moak; Yoshikazu Sado; Ichiro Naito; Yoshifumi Ninomiya; Robert Jacobs; Paul S Thorner
Transfer of the alpha 5(IV) collagen chain gene to smooth muscle restores in vivo expression of the alpha 6(IV) collagen chain in a canine model of Alport syndrome.
The American journal of pathology 2003;162(3):873-85.
2003: Junichi Hayashi; Shozo Kusachi; Takashi Murakami; Tohru Miyoshi; Keigo Nakamura; Kazuya Koten; Hiroko Ogawa; Satoshi Hirohata; Yoshifumi Ninomiya; Yasushi Shiratori
Osteogenic protein-1 reduces intercellular adhesion molecule-1 messenger RNA expression, infarct size and TUNEL-positive cardiomyocytes in ischemia/reperfusion rat hearts.
Experimental and clinical cardiology 2003;8(4):195-200.
2002: Dorin-Bogdan Borza; Olga Bondar; Parvin Todd; Munirathinam Sundaramoorthy; Yoshikazu Sado; Yoshifumi Ninomiya; Billy G Hudson
Quaternary organization of the goodpasture autoantigen, the alpha 3(IV) collagen chain. Sequestration of two cryptic autoepitopes by intrapromoter interactions with the alpha4 and alpha5 NC1 domains.
The Journal of biological chemistry 2002;277(42):40075-83.
2002: Masa-aki Kiyofuji; Ken-Ichi Iyama; Mitsuhiko Kitaoka; Yoshikazu Sado; Yoshifumi Ninomiya; Shou-ichi Ueda
Quantitative analysis of type IV collagen alpha chains in the basement membrane of human urogenital epithelium.
The Histochemical journal 2002;34(10):479-86.
2002: Kang Feng; Xiao-Hong Zhou; Toshitaka Oohashi; Matthias Mörgelin; Ariel Lustig; Satoshi Hirakawa; Yoshifumi Ninomiya; Jürgen Engel; Uwe Rauch; Reinhard Fässler
All four members of the Ten-m/Odz family of transmembrane proteins form dimers.
The Journal of biological chemistry 2002;277(29):26128-35.
2002: Norio Urabe; Ichiro Naito; Kenji Saito; Tomoko Yonezawa; Yoshikazu Sado; Hidekatsu Yoshioka; Shozo Kusachi; Takao Tsuji; Aiji Ohtsuka; Takehito Taguchi; Takuro Murakami; Yoshifumi Ninomiya
Basement membrane type IV collagen molecules in the choroid plexus, pia mater and capillaries in the mouse brain.
Archives of histology and cytology 2002;65(2):133-43.
2002: Takayuki Furumatsu; Noriko Yamaguchi; Keiichiro Nishida; Akira Kawai; Toshiyuki Kunisada; Masayoshi Namba; Hajime Inoue; Yoshifumi Ninomiya
Endostatin inhibits adhesion of endothelial cells to collagen I via alpha(2)beta(1) integrin, a possible cause of prevention of chondrosarcoma growth.
Journal of biochemistry 2002;131(4):619-26.
2002: Yutaka Hiki; Ken-Ichi Iyama; Junji Tsuruta; Hiroshi Egami; Takihiro Kamio; Shuji Suko; Ichiro Naito; Yoshikazu Sado; Yoshifumi Ninomiya; Michio Ogawa
Differential distribution of basement membrane type IV collagen alpha1(IV), alpha2(IV), alpha5(IV) and alpha6(IV) chains in colorectal epithelial tumors.
Pathology international 2002;52(3):224-33.
2002: Hiroyuki Nomoto; Toshitaka Oohashi; Satoshi Hirakawa; Yasuyoshi Ueki; Hiroshi Ohtsuki; Yoshifumi Ninomiya
Human BRAL1 and BCAN genes that belong to the link-module superfamily are tandemly arranged on chromosome 1q21-23.
Acta medica Okayama 2002;56(1):25-9.
2002: Takayuki Furumatsu; Keiichiro Nishida; Akira Kawai; Masayoshi Namba; Hajime Inoue; Yoshifumi Ninomiya
Human chondrosarcoma secretes vascular endothelial growth factor to induce tumor angiogenesis and stores basic fibroblast growth factor for regulation of its own growth.
International journal of cancer. Journal international du cancer 2002;97(3):313-22.
2002: Toshitaka Oohashi; Satoshi Hirakawa; Yoko Bekku; Uwe Rauch; Dieter R Zimmermann; Wei-Dong Su; Aiji Ohtsuka; Takuro Murakami; Yoshifumi Ninomiya
Bral1, a brain-specific link protein, colocalizing with the versican V2 isoform at the nodes of Ranvier in developing and adult mouse central nervous systems.
Molecular and cellular neurosciences 2002;19(1):43-57.
2001: Yoshifumi Ninomiya
[How are basement membranes formed?].
Seikagaku. The Journal of Japanese Biochemical Society 2001;73(10):1234-8.
2001: Scott Harvey; R Mount; Yoshikazu Sado; Ichiro Naito; Yoshifumi Ninomiya; R Harrison; Barbara Jefferson; Robert Jacobs; Paul S Thorner
The inner ear of dogs with X-linked nephritis provides clues to the pathogenesis of hearing loss in X-linked Alport syndrome.
The American journal of pathology 2001;159(3):1097-104.
2001: K Y Nakano; Ken-Ichi Iyama; T Mori; M Yoshioka; T Hiraoka; Y Sado; Yoshifumi Ninomiya
Loss of alveolar basement membrane type IV collagen alpha3, alpha4, and alpha5 chains in bronchioloalveolar carcinoma of the lung.
The Journal of pathology 2001;194(4):420-7.
2001: Dorin-Bogdan Borza; Olga Bondar; Yoshifumi Ninomiya; Yoshikazu Sado; Ichiro Naito; Parvin Todd; Billy G Hudson
The NC1 domain of collagen IV encodes a novel network composed of the alpha 1, alpha 2, alpha 5, and alpha 6 chains in smooth muscle basement membranes.
The Journal of biological chemistry 2001;276(30):28532-40.
2001: Takuro Murakami; Aiji Ohtsuka; H Matsuoka; T Taguchi; T Murakami; K Abe; Yoshifumi Ninomiya
Intensely positively charged perineuronal nets in the adult rat brain as detected by staining with anionic iron colloid.
Archives of histology and cytology 2001;64(1):45-50.
2001: Ken-Ichi Iyama; Hideaki Sumiyoshi; M Khaleduzzaman; N Matsuo; Yoshifumi Ninomiya; H Yoshioka
Differential expression of two exons of the alpha1(XI) collagen gene (Col11a1) in the mouse embryo.
Matrix biology : journal of the International Society for Matrix Biology 2001;20(1):53-61.
2001: Roy Morello; Guang Zhou; Sandra D Dreyer; Scott Harvey; Yoshifumi Ninomiya; P S Thorner; Jeffrey H Miner; W Cole; Andreas Winterpacht; Bernhard Zabel; Kerby Oberg; Brendan Lee
Regulation of glomerular basement membrane collagen expression by LMX1B contributes to renal disease in nail patella syndrome.
Nature genetics 2001;27(2):205-8.
2000: Satoshi Hirakawa; Toshitaka Oohashi; Wei-Dong Su; H Yoshioka; Takuro Murakami; J Arata; Yoshifumi Ninomiya
The brain link protein-1 (BRAL1): cDNA cloning, genomic structure, and characterization as a novel link protein expressed in adult brain.
Biochemical and biophysical research communications 2000;276(3):982-9.
2000: A Boutaud; Dorin-Bogdan Borza; Olga Bondar; S Gunwar; Kai-Olaf Netzer; N Singh; Yoshifumi Ninomiya; Yoshikazu Sado; ME Noelken; Billy G Hudson
Type IV collagen of the glomerular basement membrane. Evidence that the chain specificity of network assembly is encoded by the noncollagenous NC1 domains.
The Journal of biological chemistry 2000;275(39):30716-24.
2000: K Saito; Ichiro Naito; T Seki; Toshitaka Oohashi; E Kimura; Ryusuke Momota; Y Kishiro; Yoshikazu Sado; H Yoshioka; Yoshifumi Ninomiya
Differential expression of mouse alpha5(IV) and alpha6(IV) collagen genes in epithelial basement membranes.
Journal of biochemistry 2000;128(3):427-34.
2000: Eric Petitclerc; A Boutaud; A Prestayko; Jianguo Xu; Yoshikazu Sado; Yoshifumi Ninomiya; Michael P Sarras; Billy G Hudson; Peter C Brooks
New functions for non-collagenous domains of human collagen type IV. Novel integrin ligands inhibiting angiogenesis and tumor growth in vivo.
The Journal of biological chemistry 2000;275(11):8051-61.
1999: Takuro Murakami; Aiji Ohtsuka; Wei-Dong Su; T Taguchi; Toshitaka Oohashi; T Murakami; K Abe; Yoshifumi Ninomiya
The extracellular matrix in the mouse brain: its reactions to endo-alpha-N-acetylgalactosaminidase and certain other enzymes.
Archives of histology and cytology 1999;62(3):273-81.
1999: Keqin Zheng; S Harvey; Yoshikazu Sado; Ichiro Naito; Yoshifumi Ninomiya; Robert Jacobs; Paul S Thorner
Absence of the alpha6(IV) chain of collagen type IV in Alport syndrome is related to a failure at the protein assembly level and does not result in diffuse leiomyomatosis.
The American journal of pathology 1999;154(6):1883-91.
1999: Takuro Murakami; T Murakami; Wei-Dong Su; Aiji Ohtsuka; K Abe; Yoshifumi Ninomiya
Perineuronal nets of proteoglycans in the adult mouse brain are digested by collagenase.
Archives of histology and cytology 1999;62(2):199-204.
1998: Scott Harvey; Keqin Zheng; Yoshikazu Sado; Ichiro Naito; Yoshifumi Ninomiya; Robert M Jacobs; Billy G Hudson; Paul S Thorner
Role of distinct type IV collagen networks in glomerular development and function.
Kidney international 1998;54(6):1857-66.
1998: T Seki; Ichiro Naito; Toshitaka Oohashi; Yoshikazu Sado; Yoshifumi Ninomiya
Differential expression of type IV collagen isoforms, alpha5(IV) and alpha6(IV) chains, in basement membranes surrounding smooth muscle cells.
Histochemistry and cell biology 1998;110(4):359-66.
1998: Raul Fleischmajer; A Utani; ED MacDonald; JS Perlish; T C Pan; M L Chu; M Nomizu; Yoshifumi Ninomiya; Yoshihiko Yamada
Initiation of skin basement membrane formation at the epidermo-dermal interface involves assembly of laminins through binding to cell membrane receptors.
Journal of cell science 1998;111 ( Pt 14)():1929-40.
1998: Y L Wu; Hideaki Sumiyoshi; M Khaleduzzaman; Yoshifumi Ninomiya; Hidekatsu Yoshioka
cDNA sequence and expression of the mouse alpha1(V) collagen gene (Col5a1).
Biochimica et biophysica acta 1998;1397(3):275-84.
1998: Yoshikazu Sado; M Kagawa; Ichiro Naito; Yasuyoshi Ueki; T Seki; Ryusuke Momota; Toshitaka Oohashi; Yoshifumi Ninomiya
Organization and expression of basement membrane collagen IV genes and their roles in human disorders.
Journal of biochemistry 1998;123(5):767-76.
1998: S Gunwar; F Ballester; ME Noelken; Yoshikazu Sado; Yoshifumi Ninomiya; Billy G Hudson
Glomerular basement membrane. Identification of a novel disulfide-cross-linked network of alpha3, alpha4, and alpha5 chains of type IV collagen and its implications for the pathogenesis of Alport syndrome.
The Journal of biological chemistry 1998;273(15):8767-75.
1998: Ryusuke Momota; M Sugimoto; Toshitaka Oohashi; K Kigasawa; H Yoshioka; Yoshifumi Ninomiya
Two genes, COL4A3 and COL4A4 coding for the human alpha3(IV) and alpha4(IV) collagen chains are arranged head-to-head on chromosome 2q36.
FEBS letters 1998;424(1-2):11-6.
1998: Yoshikazu Sado; A Boutaud; M Kagawa; Ichiro Naito; Yoshifumi Ninomiya; Billy G Hudson
Induction of anti-GBM nephritis in rats by recombinant alpha 3(IV)NC1 and alpha 4(IV)NC1 of type IV collagen.
Kidney international 1998;53(3):664-71.
1998: Yasuyoshi Ueki; Ichiro Naito; Toshitaka Oohashi; M Sugimoto; T Seki; H Yoshioka; Yoshikazu Sado; H Sato; T Sawai; F Sasaki; M Matsuoka; S Fukuda; Yoshifumi Ninomiya
Topoisomerase I and II consensus sequences in a 17-kb deletion junction of the COL4A5 and COL4A6 genes and immunohistochemical analysis of esophageal leiomyomatosis associated with Alport syndrome.
American journal of human genetics 1998;62(2):253-61.
1997: M Khaleduzzaman; Hideaki Sumiyoshi; Yasuyoshi Ueki; K Inoguchi; Yoshifumi Ninomiya; Hidekatsu Yoshioka
Structure of the human type XIX collagen (COL19A1) gene, which suggests it has arisen from an ancestor gene of the FACIT family.
Genomics 1997;45(2):304-12.
1997: Raul Fleischmajer; K Kühn; Y Sato; ED MacDonald; JS Perlish; T C Pan; M L Chu; Y Kishiro; T Oohashi; S M Bernier; Yoshihiko Yamada; Yoshifumi Ninomiya
There is temporal and spatial expression of alpha1 (IV), alpha2 (IV), alpha5 (IV), alpha6 (IV) collagen chains and beta1 integrins during the development of the basal lamina in an "in vitro" skin model.
The Journal of investigative dermatology 1997;109(4):527-33.
1997: Hideaki Sumiyoshi; K Inoguchi; M Khaleduzzaman; Yoshifumi Ninomiya; Hidekatsu Yoshioka
Ubiquitous expression of the alpha1(XIX) collagen gene (Col19a1) during mouse embryogenesis becomes restricted to a few tissues in the adult organism.
The Journal of biological chemistry 1997;272(27):17104-11.
1997: K Tanaka; Ken-Ichi Iyama; Mitsuhiko Kitaoka; Yoshifumi Ninomiya; T Oohashi; Yoshikazu Sado; T Ono
Differential expression of alpha 1(IV), alpha 2(IV), alpha 5(IV) and alpha 6(IV) collagen chains in the basement membrane of basal cell carcinoma.
The Histochemical journal 1997;29(7):563-70.
1997: Yoshikazu Sado; M Kagawa; Y Kishiro; Ichiro Naito; K Joh; Yoshifumi Ninomiya
Purification and characterization of human nephritogenic antigen that induces anti-GBM nephritis in rats.
The Journal of pathology 1997;182(2):225-32.
1997: M Kagawa; Y Kishiro; Ichiro Naito; T Nemoto; H Nakanishi; Yoshifumi Ninomiya; Yoshikazu Sado
Epitope-defined monoclonal antibodies against type-IV collagen for diagnosis of Alport's syndrome.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1997;12(6):1238-41.
1996: S Hino; T Takemura; Yoshikazu Sado; M Kagawa; Toshitaka Oohashi; Yoshifumi Ninomiya; Kazuo Yoshioka
Absence of alpha 6(IV) collagen in kidney and skin of X-linked Alport syndrome patients.
Pediatric nephrology (Berlin, Germany) 1996;10(6):742-4.
1996: S Rauf; M Kagawa; Y Kishiro; S Inoue; Ichiro Naito; Toshitaka Oohashi; M Sugimoto; Yoshifumi Ninomiya; Yoshikazu Sado
Nephritogenicity and alpha-chain composition of NC1 fractions of type IV collagen from bovine renal basement membrane.
Virchows Archiv : an international journal of pathology 1996;428(4-5):281-8.
1995: Toshitaka Oohashi; Y Ueki; M Sugimoto; Yoshifumi Ninomiya
Isolation and structure of the COL4A6 gene encoding the human alpha 6(IV) collagen chain and comparison with other type IV collagen genes.
The Journal of biological chemistry 1995;270(45):26863-7.
1995: Yoshifumi Ninomiya
[Type IV collagen: gene expression, supramolecular aggregates, and role in human diseases].
Seikagaku. The Journal of Japanese Biochemical Society 1995;67(11):1301-7.
1995: Yoshikazu Sado; M Kagawa; Y Kishiro; K Sugihara; Ichiro Naito; J M Seyer; M Sugimoto; Toshitaka Oohashi; Yoshifumi Ninomiya
Establishment by the rat lymph node method of epitope-defined monoclonal antibodies recognizing the six different alpha chains of human type IV collagen.
Histochemistry and cell biology 1995;104(4):267-75.
1995: Hidekatsu Yoshioka; K Iyama; K Inoguchi; M Khaleduzzaman; Yoshifumi Ninomiya; F Ramirez
Developmental pattern of expression of the mouse alpha 1 (XI) collagen gene (Col11a1).
Developmental dynamics : an official publication of the American Association of Anatomists 1995;204(1):41-7.
1995: Yoshifumi Ninomiya; M Kagawa; Ken-Ichi Iyama; Ichiro Naito; Y Kishiro; J M Seyer; M Sugimoto; Toshitaka Oohashi; Yoshikazu Sado
Differential expression of two basement membrane collagen genes, COL4A6 and COL4A5, demonstrated by immunofluorescence staining using peptide-specific monoclonal antibodies.
The Journal of cell biology 1995;130(5):1219-29.
1995: Hidekatsu Yoshioka; K Inoguchi; M Khaleduzzaman; Yoshifumi Ninomiya; K Andrikopoulos; F Ramirez
Coding sequence and alternative splicing of the mouse alpha 1(XI) collagen gene (Col11a1).
Genomics 1995;28(2):337-40.
1995: Hidekatsu Yoshioka; Patricia Greenwel; K Inoguchi; S Truter; Y Inagaki; Yoshifumi Ninomiya; F Ramirez
Structural and functional analysis of the promoter of the human alpha 1(XI) collagen gene.
The Journal of biological chemistry 1995;270(1):418-24.
1995: K Inoguchi; Hidekatsu Yoshioka; M Khaleduzzaman; Yoshifumi Ninomiya
The mRNA for alpha 1(XIX) collagen chain, a new member of FACITs, contains a long unusual 3' untranslated region and displays many unique splicing variants.
Journal of biochemistry 1995;117(1):137-46.
1994: M Sugimoto; Toshitaka Oohashi; Yoshifumi Ninomiya
The genes COL4A5 and COL4A6, coding for basement membrane collagen chains alpha 5(IV) and alpha 6(IV), are located head-to-head in close proximity on human chromosome Xq22 and COL4A6 is transcribed from two alternative promoters.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(24):11679-83.
1994: Toshitaka Oohashi; M Sugimoto; M G Mattei; Yoshifumi Ninomiya
Identification of a new collagen IV chain, alpha 6(IV), by cDNA isolation and assignment of the gene to chromosome Xq22, which is the same locus for COL4A5.
The Journal of biological chemistry 1994;269(10):7520-6.
1994: N Abe; Hidekatsu Yoshioka; H Inoue; Yoshifumi Ninomiya
The complete primary structure of the long form of mouse alpha 1(IX) collagen chain and its expression during limb development.
Biochimica et biophysica acta 1994;1204(1):61-7.