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Motohiro Nishida

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Motohiro Nishida; Shota Saiki; Caroline Sunggip; Koichiro Kuwahara; Yasuo Mori; Shizuka Aritomi; Eri Harada; Katsuya Hirano; Tatsuya Ishikawa; Shokei Kim-Mitsuyama
Voltage-dependent N-type Ca(2+) channels in endothelial cells contribute to oxidative stress-related endothelial dysfunction induced by angiotensin II in mice.
Motohiro Nishida; Masaaki Sumita; Naoyuki Kitajima
[The Roles of Calcium and Phosphorus in Cardiovascular Diseases. Function and role of transient receptor potential channels].
Takaaki Akaike; Motohiro Nishida; Shigemoto Fujii
Regulation of redox signalling by an electrophilic cyclic nucleotide.

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2013: Motohiro Nishida; Shota Saiki; Caroline Sunggip; Koichiro Kuwahara; Yasuo Mori; Shizuka Aritomi; Eri Harada; Katsuya Hirano; Tatsuya Ishikawa; Shokei Kim-Mitsuyama
Voltage-dependent N-type Ca(2+) channels in endothelial cells contribute to oxidative stress-related endothelial dysfunction induced by angiotensin II in mice.
Biochemical and biophysical research communications 2013;434(2):210-6.
2013: Motohiro Nishida; Masaaki Sumita; Naoyuki Kitajima
[The Roles of Calcium and Phosphorus in Cardiovascular Diseases. Function and role of transient receptor potential channels].
Clinical calcium 2013;23(4):561-8.
2013: Takaaki Akaike; Motohiro Nishida; Shigemoto Fujii
Regulation of redox signalling by an electrophilic cyclic nucleotide.
Journal of biochemistry 2013;153(2):131-8.
2013: Michio Nakaya; Takeo Nakaya; Motohiro Nishida; Hiroaki Nishihara; Mina Ohba; Yoji Sato; Mitsuru Tajima; Naoki Tani; Hisaaki Taniguchi; Makoto Tsuda; Kenji Watari; Akiko Hashimoto; Kazuhide Inoue; Shiori Komiya; Hidetaka Kosako; Masahiko Kuroda; Mitsuru Matsumoto; Hitoshi Kurose
GRK6 deficiency in mice causes autoimmune disease due to impaired apoptotic cell clearance.
Nature communications 2013;4():1532.
2013: Caroline Sunggip; Naoyuki Kitajima; Motohiro Nishida
Redox Control of Cardiovascular Homeostasis by Angiotensin II.
Current pharmaceutical design 2013;19(17):3022-32.
2012: Motohiro Nishida; Katsuhiko Ono; Tomohiro Sawa; Takahiro Shibata; Makoto Suematsu; Koji Uchida; Albert van der Vliet; Masayuki Yamamoto; Bruce A Freeman; Hideshi Ihara; Hirofumi Inoue; Naoyuki Kitajima; Yoshito Kumagai; Hitoshi Kurose; Hozumi Motohashi; Takaaki Akaike
Hydrogen sulfide anion regulates redox signaling via electrophile sulfhydration.
Nature chemical biology 2012;8(8):714-24.
2011: Kinue Nishioka; Shota Saiki; Yoji Sato; Michio Nakaya; Motohiro Nishida; Marina Ariyoshi; Katsuya Hirano; Mayumi Hirano; Ryuji Inoue; Takahiro Iwamoto; Zhong Jian; Satomi Kita; Hitoshi Kurose
Cilostazol suppresses angiotensin II-induced vasoconstriction via protein kinase A-mediated phosphorylation of the transient receptor potential canonical 6 channel.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(10):2278-86.
2011: Motohiro Nishida; Shota Saiki; Naoyuki Kitajima; Michio Nakaya; Hitoshi Kurose
Regulation of Angiotensin II receptor signaling by cysteine modification of NF-κB.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2011;25(2):112-7.
2011: Naoyuki Kitajima; Kunihiro Watanabe; Sachio Morimoto; Yoji Sato; Shigeki Kiyonaka; Masahiko Hoshijima; Yasuhiro Ikeda; Michio Nakaya; Tomomi Ide; Yasuo Mori; Hitoshi Kurose; Motohiro Nishida
TRPC3-mediated Ca2+ influx contributes to Rac1-mediated production of reactive oxygen species in MLP-deficient mouse hearts.
Biochemical and biophysical research communications 2011;409(1):108-13.
2011: Motohiro Nishida; Mariko Ogushi; Reiko Suda; Miyuki Toyotaka; Shota Saiki; Naoyuki Kitajima; Michio Nakaya; Kyeong-Man Kim; Tomomi Ide; Yoji Sato; Kazuhide Inoue; Hitoshi Kurose
Heterologous down-regulation of angiotensin type 1 receptors by purinergic P2Y2 receptor stimulation through S-nitrosylation of NF-kappaB.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(16):6662-7.
2011: Motohiro Nishida
Roles of heterotrimeric GTP-binding proteins in the progression of heart failure.
Journal of pharmacological sciences 2011;117(1):1-5.
2011: Michio Nakaya; Motohiro Nishida; Mina Ohba; Hitoshi Kurose
Determining the activation of rho as an index of receptor coupling to G₁₂/₁₃ proteins.
Methods in molecular biology (Clifton, N.J.) 2011;746():317-27.
2010: Motohiro Nishida; Shota Saiki; Naoyuki Kitajima; Michio Nakaya; Yoji Sato; Hitoshi Kurose
[Regulation of cardiovascular functions by the phosphorylation of TRPC channels].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2010;130(11):1427-33.
2010: Motohiro Nishida
[Signal transduction in the development of vascular disease and new therapeutic strategy].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2010;130(11):1397.
2010: Motohiro Nishida; Reiko Suda; Yuichi Nagamatsu; Shihori Tanabe; Naoya Onohara; Michio Nakaya; Yasunori Kanaho; Takahiro Shibata; Koji Uchida; Hideki Sumimoto; Yoji Sato; Hitoshi Kurose
Pertussis toxin up-regulates angiotensin type 1 receptors through Toll-like receptor 4-mediated Rac activation.
The Journal of biological chemistry 2010;285(20):15268-77.
2010: Motohiro Nishida; Kenta Watanabe; Yoji Sato; Michio Nakaya; Naoyuki Kitajima; Tomomi Ide; Ryuji Inoue; Hitoshi Kurose
Phosphorylation of TRPC6 channels at Thr69 is required for anti-hypertrophic effects of phosphodiesterase 5 inhibition.
The Journal of biological chemistry 2010;285(17):13244-53.
2010: Motohiro Nishida; Kenta Watanabe; Michio Nakaya; Hitoshi Kurose
[Mechanism of cardiac hypertrophy via diacylglycerol-sensitive TRPC channels].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2010;130(3):295-302.
2010: Motohiro Nishida
[ Frontiers of Ca(2+) signaling~physiological and pathological roles of voltage-independent Ca(2+) channels].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2010;130(3):279-80.
2008: Motohiro Nishida; Yoji Sato; Aya Uemura; Yusuke Narita; Hidetoshi Tozaki-Saitoh; Michio Nakaya; Tomomi Ide; Kazuhiro Suzuki; Kazuhide Inoue; Taku Nagao; Hitoshi Kurose
P2Y6 receptor-Galpha12/13 signalling in cardiomyocytes triggers pressure overload-induced cardiac fibrosis.
The EMBO journal 2008;27(23):3104-15.
2008: Motohiro Nishida; Hitoshi Kurose
Roles of TRP channels in the development of cardiac hypertrophy.
Naunyn-Schmiedeberg's archives of pharmacology 2008;378(4):395-406.
2007: Hitoshi Kurose; Motohiro Nishida
[TRPC channels and cardiac hypertrophy].
Seikagaku. The Journal of Japanese Biochemical Society 2007;79(10):953-6.
2007: Motohiro Nishida; Naoya Onohara; Yoji Sato; Reiko Suda; Mariko Ogushi; Shihori Tanabe; Ryuji Inoue; Yasuo Mori; Hitoshi Kurose
Galpha12/13-mediated up-regulation of TRPC6 negatively regulates endothelin-1-induced cardiac myofibroblast formation and collagen synthesis through nuclear factor of activated T cells activation.
The Journal of biological chemistry 2007;282(32):23117-28.
2006: Naoya Onohara; Motohiro Nishida; Ryuji Inoue; Hiroyuki Kobayashi; Hideki Sumimoto; Yoji Sato; Yasuo Mori; Taku Nagao; Hitoshi Kurose
TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy.
The EMBO journal 2006;25(22):5305-16.
2006: Supachoke Mangmool; Tatsuya Haga; Hiroyuki Kobayashi; Kyeong-Man Kim; Hiroyasu Nakata; Motohiro Nishida; Hitoshi Kurose
Clathrin required for phosphorylation and internalization of beta2-adrenergic receptor by G protein-coupled receptor kinase 2 (GRK2).
The Journal of biological chemistry 2006;281(42):31940-9.
2006: Motohiro Nishida; Yuji Hara; Takashi Yoshida; Ryuji Inoue; Yasuo Mori
TRP channels: molecular diversity and physiological function.
Microcirculation (New York, N.Y. : 1994) 2006;13(7):535-50.
2006: Yuichi Nagamatsu; Motohiro Nishida; Naoya Onohara; Masashi Fukutomi; Yoshiko Maruyama; Hiroyuki Kobayashi; Yoji Sato; Hitoshi Kurose
Heterotrimeric G protein G alpha13-induced induction of cytokine mRNAs through two distinct pathways in cardiac fibroblasts.
Journal of pharmacological sciences 2006;101(2):144-50.
2005: Hiroyuki Kobayashi; Yusuke Narita; Motohiro Nishida; Hitoshi Kurose
Beta-arrestin2 enhances beta2-adrenergic receptor-mediated nuclear translocation of ERK.
Cellular signalling 2005;17(10):1248-53.
2005: Tomomi Fujii; Naoya Onohara; Yoshiko Maruyama; Shihori Tanabe; Hiroyuki Kobayashi; Masashi Fukutomi; Yuichi Nagamatsu; Naoki Nishihara; Ryuji Inoue; Hideki Sumimoto; Futoshi Shibasaki; Taku Nagao; Motohiro Nishida; Hitoshi Kurose
Galpha12/13-mediated production of reactive oxygen species is critical for angiotensin receptor-induced NFAT activation in cardiac fibroblasts.
The Journal of biological chemistry 2005;280(24):23041-7.
2005: Masashi Fukutomi; Motohiro Nishida; Yoshiko Maruyama; Hiroyuki Kobayashi; Hitoshi Kurose
Caveolae-independent activation of protein kinase A in rat neonatal myocytes.
Journal of pharmacological sciences 2005;98(2):168-74.
2005: Motohiro Nishida; Shihori Tanabe; Yoshiko Maruyama; Supachoke Mangmool; Kyoji Urayama; Yuichi Nagamatsu; Shuichi Takagahara; Justin H Turner; Tohru Kozasa; Hiroyuki Kobayashi; Yoji Sato; Toru Kawanishi; Ryuji Inoue; Taku Nagao; Hitoshi Kurose
G alpha 12/13- and reactive oxygen species-dependent activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase by angiotensin receptor stimulation in rat neonatal cardiomyocytes.
The Journal of biological chemistry 2005;280(18):18434-41.
2003: Ken Arai; Yoshiko Maruyama; Motohiro Nishida; Shihori Tanabe; Shuichi Takagahara; Tohru Kozasa; Yasuo Mori; Taku Nagao; Hitoshi Kurose
Differential requirement of G alpha12, G alpha13, G alphaq, and G beta gamma for endothelin-1-induced c-Jun NH2-terminal kinase and extracellular signal-regulated kinase activation.
Molecular pharmacology 2003;63(3):478-88.
2002: Yoshiko Maruyama; Motohiro Nishida; Yoshiyuki Sugimoto; Shihori Tanabe; Justin H Turner; Tohru Kozasa; Teiji Wada; Taku Nagao; Hitoshi Kurose
Galpha(12/13) mediates alpha(1)-adrenergic receptor-induced cardiac hypertrophy.
Circulation research 2002;91(10):961-9.
2002: Motohiro Nishida; Kevin L Schey; Shuichi Takagahara; Kenji Kontani; Toshiaki Katada; Yasuteru Urano; Tetsuo Nagano; Taku Nagao; Hitoshi Kurose
Activation mechanism of Gi and Go by reactive oxygen species.
The Journal of biological chemistry 2002;277(11):9036-42.
2002: Motohiro Nishida; Shuichi Takagahara; Yoshiko Maruyama; Yoshiyuki Sugimoto; Taku Nagao; Hitoshi Kurose
G beta gamma counteracts G alpha(q) signaling upon alpha(1)-adrenergic receptor stimulation.
Biochemical and biophysical research communications 2002;291(4):995-1000.
2000: Motohiro Nishida; Yoshiko Maruyama; R Tanaka; Kenji Kontani; Taku Nagao; Hitoshi Kurose
G alpha(i) and G alpha(o) are target proteins of reactive oxygen species.
Nature 2000;408(6811):492-5.
1999: Motohiro Nishida; Taku Nagao; Hitoshi Kurose
Activation of Rac1 increases c-Jun NH(2)-terminal kinase activity and DNA fragmentation in a calcium-dependent manner in rat myoblast cell line H9c2.
Biochemical and biophysical research communications 1999;262(2):350-4.