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Koji Nishifuji

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K Ide; Toshiroh Iwasaki; K Iyori; T Mochizuki; R Fukushima; N Uchida; Koji Nishifuji
Multi-system progressive angiomatosis in a dog resembling blue rubber bleb nevus syndrome in humans.
Laramie D Winfield; Verena K Affolter; Dominic Dawson; Keita Iyori; Thierry Olivry; Catherine A Outerbridge; Anna C Renier; Yu Hsuan Wang; Stephen D White; Koji Nishifuji
Pemphigus vulgaris in a Welsh pony stallion: case report and demonstration of antidesmoglein autoantibodies.
Keita Iyori; Kaori Ide; Toshiroh Iwasaki; Yoichi Toyoda; Koji Nishifuji
Usefulness of cefovecin disk-diffusion test for predicting mecA gene-containing strains of Staphylococcus pseudintermedius and clinical efficacy of cefovecin in dogs with superficial pyoderma.

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2013: K Ide; Toshiroh Iwasaki; K Iyori; T Mochizuki; R Fukushima; N Uchida; Koji Nishifuji
Multi-system progressive angiomatosis in a dog resembling blue rubber bleb nevus syndrome in humans.
The Journal of small animal practice 2013;54(4):201-4.
2013: Laramie D Winfield; Verena K Affolter; Dominic Dawson; Keita Iyori; Thierry Olivry; Catherine A Outerbridge; Anna C Renier; Yu Hsuan Wang; Stephen D White; Koji Nishifuji
Pemphigus vulgaris in a Welsh pony stallion: case report and demonstration of antidesmoglein autoantibodies.
Veterinary dermatology 2013;24(2):269-e60.
2013: Keita Iyori; Kaori Ide; Toshiroh Iwasaki; Yoichi Toyoda; Koji Nishifuji
Usefulness of cefovecin disk-diffusion test for predicting mecA gene-containing strains of Staphylococcus pseudintermedius and clinical efficacy of cefovecin in dogs with superficial pyoderma.
Veterinary dermatology 2013;24(1):162-7.e35-6.
2013: Ji-Seon Yoon; Koji Nishifuji; Kaori Ide; Sinpei Ishioroshi; Toshiroh Iwasaki
Skin lipid profiling in normal and seborrhoeic shih tzu dogs.
Veterinary dermatology 2013;24(1):84-9.e21-2.
2013: Tetsuro Kobayashi; Kaoru Enomoto; Kaori Ide; Toshiroh Iwasaki; Toshio Nishiyama; Manabu Ohyama; Ryoko Okamura; Yu Hsuan Wang; Ji Seon Yoon; Koji Nishifuji
Epidermal structure created by canine hair follicle keratinocytes enriched with bulge cells in a three-dimensional skin equivalent model in vitro: implications for regenerative therapy of canine epidermis.
Veterinary dermatology 2013;24(1):77-83.e19-20.
2013: Koji Nishifuji; Ji Seon Yoon
The stratum corneum: the rampart of the mammalian body.
Veterinary dermatology 2013;24(1):60-72.e15-6.
2013: Satoko Kanda; Masayuki Amagai; Toshiroh Iwasaki; Koji Nishifuji; Takashi Sasaki; Aiko Shiohama; Jun Kudoh
Characterization of canine filaggrin: gene structure and protein expression in dog skin.
Veterinary dermatology 2013;24(1):25-31.e7.
2012: Masafumi Sato; Miyuki Itoh; Junichi Kamiie; Kazuhiro Kariya; Yoshiyasu Kobayashi; Munetaka Matsumoto; Koji Nishifuji; Kinji Shirota
Feline epidermal nevi resembling human inflammatory linear verrucous epidermal nevus.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2012;74(10):1337-9.
2012: Bungo Ohyama; Daisuke Tsuruta; Takuto Yamashita; Masayuki Amagai; Po Tak Chan; Teruki Dainichi; Takahiro Hamada; Norito Ishii; Atsushi Kawaguchi; Hiroshi Koga; Koji Nishifuji; Takashi Hashimoto
Epitope spreading is rarely found in pemphigus vulgaris by large-scale longitudinal study using desmoglein 2-based swapped molecules.
The Journal of investigative dermatology 2012;132(4):1158-68.
2011: Naoki Chimura; Yuki Hoshino; Kaori Ide; Hiroaki Kamishina; Tsuyoshi Kimura; Naho Kondo; Takashi Mori; Nobuo Murayama; Masahiko Nagata; Koji Nishifuji; Sanae Shibata; Sadatoshi Maeda
Gene transcription analysis in lesional skin of canine epitheliotropic cutaneous lymphoma using quantitative real-time RT-PCR.
Veterinary immunology and immunopathology 2011;144(3-4):329-36.
2011: Ji-Seon Yoon; Toru Yoshihara; Kaori Ide; Junko Ishikawa; Koji Nishifuji; Ako Sasaki; Toshiroh Iwasaki
Alteration of stratum corneum ceramide profiles in spontaneous canine model of atopic dermatitis.
Experimental dermatology 2011;20(9):732-6.
2011: Keita Iyori; Tsuguaki Fukuyasu; Keiko Futagawa-Saito; Junzo Hisatsune; Kaori Ide; Toshiroh Iwasaki; Thierry Olivry; Maiko Sekiguchi; Won-Geun Son; Motoyuki Sugai; Masahiko Yamamoto; Koji Nishifuji
Staphylococcus pseudintermedius exfoliative toxin EXI selectively digests canine desmoglein 1 and causes subcorneal clefts in canine epidermis.
Veterinary dermatology 2011;22(4):319-26.
2011: Tsuyoshi Hata; Koji Nishifuji; Kouji Shimoda; Takashi Sasaki; Taketo Yamada; Takeji Nishikawa; Shigeo Koyasu; Masayuki Amagai
Transgenic rescue of desmoglein 3 null mice with desmoglein 1 to develop a syngeneic mouse model for pemphigus vulgaris.
Journal of dermatological science 2011;63(1):33-9.
2011: Koji Nishifuji
Heterogeneity of circulating autoantibody profiles in canine autoimmune subepidermal blistering dermatoses.
Veterinary dermatology 2011;22(1):118.
2011: Naoko Wada; Koji Nishifuji; Taketo Yamada; Jun Kudoh; Nobuyoshi Shimizu; Mitsuru Matsumoto; Leena Peltonen; Seiho Nagafuchi; Masayuki Amagai
Aire-dependent thymic expression of desmoglein 3, the autoantigen in pemphigus vulgaris, and its role in T-cell tolerance.
The Journal of investigative dermatology 2011;131(2):410-7.
2010: Tetsuji Kawakami; Sanae Shibata; Nobuo Murayama; Masahiko Nagata; Koji Nishifuji; Toshiroh Iwasaki; Tsuneo Fukata
Antimicrobial susceptibility and methicillin resistance in Staphylococcus pseudintermedius and Staphylococcus schleiferi subsp. coagulans isolated from dogs with pyoderma in Japan.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2010;72(12):1615-9.
2010: Keita Iyori; Junzo Hisatsune; Tetsuji Kawakami; Sanae Shibata; Nobuo Murayama; Kaori Ide; Masahiko Nagata; Tsuneo Fukata; Toshiroh Iwasaki; Kenshiro Oshima; Masahira Hattori; Motoyuki Sugai; Koji Nishifuji
Identification of a novel Staphylococcus pseudintermedius exfoliative toxin gene and its prevalence in isolates from canines with pyoderma and healthy dogs.
FEMS microbiology letters 2010;312(2):169-75.
2010: Ji-Seon Yoon; Tomohiko Minami; Yasuko Takizawa; Maiko Sekiguchi; Atsushi Yabuzoe; Kaori Ide; Koji Nishifuji; Toshiroh Iwasaki
Two dogs with juvenile-onset skin diseases with involvement of extremities.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2010;72(11):1513-6.
2010: Kaori Ide; Waka Yamamoto; Masafumi Sato; Atsushi Yabuzoe; Toshiroh Iwasaki; Koji Nishifuji
Expression analysis of desmosomal components of the novel canine epidermal keratinocyte cell line (MSCEK).
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2010;72(11):1479-82.
2010: Koji Nishifuji; Atsushi Shimizu; Akira Ishiko; Toshiroh Iwasaki; Masayuki Amagai
Removal of amino-terminal extracellular domains of desmoglein 1 by staphylococcal exfoliative toxin is sufficient to initiate epidermal blister formation.
Journal of dermatological science 2010;59(3):184-91.
2010: P T Chan; B Ohyama; Koji Nishifuji; Kazue Yoshida; Ken Ishii; Takashi Hashimoto; Masayuki Amagai
Immune response towards the amino-terminus of desmoglein 1 prevails across different activity stages in nonendemic pemphigus foliaceus.
The British journal of dermatology 2010;162(6):1242-50.
2009: Atsushi Yabuzoe; Shin-ichi Yokoi; Maiko Sekiguchi; Yasuyuki Momoi; Kaori Ide; Koji Nishifuji; Toshiroh Iwasaki
Fibrodysplasia ossificans progressiva in a Maine Coon cat with prominent ossification in dorsal muscle.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2009;71(12):1649-52.
2009: Kenichiro Shimada; Ji-Seon Yoon; Toru Yoshihara; Toshiroh Iwasaki; Koji Nishifuji
Increased transepidermal water loss and decreased ceramide content in lesional and non-lesional skin of dogs with atopic dermatitis.
Veterinary dermatology 2009;20(5-6):541-6.
2009: Tetsuro Kobayashi; Atsushi Shimizu; Koji Nishifuji; Masayuki Amagai; Toshiroh Iwasaki; Manabu Ohyama
Canine hair-follicle keratinocytes enriched with bulge cells have the highly proliferative characteristic of stem cells.
Veterinary dermatology 2009;20(5-6):338-46.
2009: Koji Nishifuji; Kei Tamura; Hitomi Konno; Thierry Olivry; Masayuki Amagai; Toshiroh Iwasaki
Development of an enzyme-linked immunosorbent assay for detection of circulating IgG autoantibodies against canine desmoglein 3 in dogs with pemphigus.
Veterinary dermatology 2009;20(5-6):331-7.
2009: Atsushi Yabuzoe; Atushi Shimizu; Koji Nishifuji; Yasuyuki Momoi; Akira Ishiko; Toshiroh Iwasaki
Canine pemphigus foliaceus antigen is localized within desmosomes of keratinocyte.
Veterinary immunology and immunopathology 2009;127(1-2):57-64.
2008: Kazufumi Kuga; Koji Nishifuji; Toshiroh Iwasaki
Cyclosporine A inhibits transcription of cytokine genes and decreases the frequencies of IL-2 producing cells in feline mononuclear cells.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2008;70(10):1011-6.
2008: Kenichiro Shimada; Toru Yoshihara; Masahiko Yamamoto; Katsuhiko Konno; Yasuyuki Momoi; Koji Nishifuji; Toshiroh Iwasaki
Transepidermal water loss (TEWL) reflects skin barrier function of dog.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2008;70(8):841-3.
2008: Atsushi Yabuzoe; Koji Nishifuji; Maiko Sekiguchi; Atsushi Shimizu; Yasuyuki Momoi; Akira Ishiko; Toshiroh Iwasaki
Neutrophils contact to plasma membrane of keratinocytes including desmosomal structures in canine pemphigus foliaceus.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2008;70(8):807-12.
2008: Koji Nishifuji; Motoyuki Sugai; Masayuki Amagai
Staphylococcal exfoliative toxins: "molecular scissors" of bacteria that attack the cutaneous defense barrier in mammals.
Journal of dermatological science 2008;49(1):21-31.
2007: Masako Kawachi; Katsuto Tamai; Kotaro Saga; Takehiko Yamazaki; Hiroshi Fujita; Takashi Shimbo; Yasushi Kikuchi; Keisuke Nimura; Koji Nishifuji; Masayuki Amagai; Jouni Uitto; Yasufumi Kaneda
Development of tissue-targeting hemagglutinating virus of Japan envelope vector for successful delivery of therapeutic gene to mouse skin.
Human gene therapy 2007;18(10):881-94.
2007: M Heimann; L Beco; M Petein; Koji Nishifuji; M Amagai; Thierry Olivry; D T Olivry
Canine hyperplastic intraepidermal pustular and suprabasal acantholytic dermatosis with features of human pemphigus vegetans.
Veterinary pathology 2007;44(4):550-5.
2007: Koji Nishifuji; Thierry Olivry; Ken Ishii; Toshiroh Iwasaki; Masayuki Amagai
IgG autoantibodies directed against desmoglein 3 cause dissociation of keratinocytes in canine pemphigus vulgaris and paraneoplastic pemphigus.
Veterinary immunology and immunopathology 2007;117(3-4):209-21.
2007: Koji Nishifuji; Seong-Jun Park; Toshiroh Iwasaki
A case of hyperplastic dermatosis of the West Highland White Terrier controlled by recombinant canine interferon-gamma therapy.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2007;69(4):455-7.
2006: Koji Nishifuji; Masayuki Amagai
[Loss of adhesive function of desmosomal cadherin and skin diseases in humans and animals].
Seikagaku. The Journal of Japanese Biochemical Society 2006;78(7):609-14.
2006: Koji Nishifuji; Masayuki Amagai
[Loss of adhesive function of desmogleins in bullous diseases: pemphigus and impetigo].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2006;51(6 Suppl):796-802.
2005: Koji Nishifuji; Y Ueda; Ayako Sano; M Kadoya; K Kamei; M Sekiguchi; K Nishimura; T Iwasaki
Interdigital involvement in a case of primary cutaneous canine histoplasmosis in Japan.
Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 2005;52(9):478-80.
2005: Yasuhiro Fudaba; Koji Nishifuji; Lars Ole Andresen; Takayuki Yamaguchi; Hitoshi Komatsuzawa; Masayuki Amagai; Motoyuki Sugai
Staphylococcus hyicus exfoliative toxins selectively digest porcine desmoglein 1.
Microbial pathogenesis 2005;39(5-6):171-6.
2005: Koji Nishifuji; Yasuhiro Fudaba; Takayuki Yamaguchi; Toshiroh Iwasaki; Motoyuki Sugai; Masayuki Amagai
Cloning of swine desmoglein 1 and its direct proteolysis by Staphylococcus hyicus exfoliative toxins isolated from pigs with exudative epidermitis.
Veterinary dermatology 2005;16(5):315-23.
2005: Koji Nishifuji; Kumiko Yoshida-Yamakita; Toshiroh Iwasaki
A canine pemphigus foliaceus case showing parallel relationship of disease activity and titer of serum anti-keratinocyte cell surface antibodies.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2005;67(9):943-5.
2004: Takeshi Nagasaka; Koji Nishifuji; Takayuki Ota; Neil Whittock; Masayuki Amagai
Defining the pathogenic involvement of desmoglein 4 in pemphigus and staphylococcal scalded skin syndrome.
The Journal of clinical investigation 2004;114(10):1484-92.
2004: Masayuki Shida; Michiyo Kadoya; Seong-Jun Park; Koji Nishifuji; Yasuyuki Momoi; Toshiroh Iwasaki
Allergen-specific immunotherapy induces Th1 shift in dogs with atopic dermatitis.
Veterinary immunology and immunopathology 2004;102(1-2):19-31.
2004: R Honda; Koji Nishifuji; Thierry Olivry; Stephen D White; Yasuyuki Momoi; Toshiroh Iwasaki
Detection of circulating autoantibodies using living keratinocyte staining on MCA-B1 method in dogs with pemphigus foliaceus.
Research in veterinary science 2004;77(2):105-13.
2004: Hidemi Anzai; Yoshiko Fujii; Koji Nishifuji; Miyo Aoki-Ota; Takayuki Ota; Masayuki Amagai; Takeji Nishikawa
Conformational epitope mapping of antibodies against desmoglein 3 in experimental murine pemphigus vulgaris.
Journal of dermatological science 2004;35(2):133-42.
2004: Yasushi Hanakawa; Norman M Schechter; Chenyan Lin; Koji Nishifuji; Masayuki Amagai; John R Stanley
Enzymatic and molecular characteristics of the efficiency and specificity of exfoliative toxin cleavage of desmoglein 1.
The Journal of biological chemistry 2004;279(7):5268-77.
2003: Koji Nishifuji; Masayuki Amagai; Takeji Nishikawa; Toshiroh Iwasaki
Production of recombinant extracellular domains of canine desmoglein 1 (Dsg1) by baculovirus expression.
Veterinary immunology and immunopathology 2003;95(3-4):177-82.
2003: Koji Nishifuji; Masayuki Amagai; Takayuki Ota; Takeji Nishikawa; Toshiroh Iwasaki
Cloning of canine desmoglein 3 and immunoreactivity of serum antibodies in human and canine pemphigus vulgaris with its extracellular domains.
Journal of dermatological science 2003;32(3):181-91.
2002: M Kadoya-Minegishi; S J Park; M Sekiguchi; Koji Nishifuji; Yasuyuki Momoi; Toshiroh Iwasaki
The use of fluorescein as a contrast medium to enhance intradermal skin tests in cats.
Australian veterinary journal 2002;80(11):702-3.
2002: Takayuki Yamaguchi; Koji Nishifuji; Megumi Sasaki; Yasuhiro Fudaba; Martin Aepfelbacher; Takashi Takata; Masaru Ohara; Hitoshi Komatsuzawa; Masayuki Amagai; Motoyuki Sugai
Identification of the Staphylococcus aureus etd pathogenicity island which encodes a novel exfoliative toxin, ETD, and EDIN-B.
Infection and immunity 2002;70(10):5835-45.
2002: Stephen D White; Didier N Carlotti; Didier Pin; Terri Bonenberger; Peter J Ihrke; Eric Monet; Koji Nishifuji; Toshiroh Iwasaki; Mark G Papich
Putative drug-related pemphigus foliaceus in four dogs.
Veterinary dermatology 2002;13(4):195-202.
2002: Yasushi Hanakawa; Norman M Schechter; Chenyan Lin; Luis Garza; Hong Li; Takayuki Yamaguchi; Yasuhiro Fudaba; Koji Nishifuji; Motoyuki Sugai; Masayuki Amagai; John R Stanley
Molecular mechanisms of blister formation in bullous impetigo and staphylococcal scalded skin syndrome.
The Journal of clinical investigation 2002;110(1):53-60.
2002: Masayuki Amagai; Takayuki Yamaguchi; Yasushi Hanakawa; Koji Nishifuji; Motoyuki Sugai; John R Stanley
Staphylococcal exfoliative toxin B specifically cleaves desmoglein 1.
The Journal of investigative dermatology 2002;118(5):845-50.
2002: Song-Jung Park; Naoko Yoshida; Koji Nishifuji; Maiko Sekiguchi; Yasuyuki Momoi; Tsuneo Fukada; Toshiroh Iwasaki
Successful treatment of two dogs with allergic dermatitis by anti-allergic peptides (MS-antigen).
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2002;64(1):63-5.
2000: Yuko Futei; Masayuki Amagai; M Sekiguchi; Koji Nishifuji; Yoshiko Fujii; Takeji Nishikawa
Use of domain-swapped molecules for conformational epitope mapping of desmoglein 3 in pemphigus vulgaris.
The Journal of investigative dermatology 2000;115(5):829-34.
2000: S Park; F Ohya; K Yamashita; Koji Nishifuji; Toshiroh Iwasaki
Comparison of response to immunotherapy by intradermal skin test and antigen-specific IgE in canine atopy.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2000;62(9):983-8.
2000: Masayuki Amagai; Kazuyuki Tsunoda; Harumi Suzuki; Koji Nishifuji; Shigeo Koyasu; Takeji Nishikawa
Use of autoantigen-knockout mice in developing an active autoimmune disease model for pemphigus.
The Journal of clinical investigation 2000;105(5):625-31.
2000: Koji Nishifuji; Masayuki Amagai; Masataka Kuwana; Toshiroh Iwasaki; Takeji Nishikawa
Detection of antigen-specific B cells in patients with pemphigus vulgaris by enzyme-linked immunospot assay: requirement of T cell collaboration for autoantibody production.
The Journal of investigative dermatology 2000;114(1):88-94.