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Yoshitake Nishimune

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Hitoshi Tainaka; Hikari Takahashi; Yoshitake Nishimune; Shigeru Oshio; Hiromitsu Tanaka; Masakazu Umezawa; Ken Takeda
Evaluation of the testicular toxicity of prenatal exposure to bisphenol A based on microarray analysis combined with MeSH annotation.
Hikari Takahashi; Ken Takeda; Hiromitsu Tanaka; Masakazu Umezawa; Yoshitake Nishimune; Hitoshi Tainaka; Shigeru Oshio
Evaluation of testicular toxicology of doxorubicin based on microarray analysis of testicular specific gene expression.
Keizo Tokuhiro; Ayako Isotani; Sadaki Yokota; Yoshihisa Yano; Shigeru Oshio; Mika Hirose; Morimasa Wada; Kyoko Fujita; Yukiko Ogawa; Masaru Okabe; Yoshitake Nishimune; Hiromitsu Tanaka
OAZ-t/OAZ3 is essential for rigid connection of sperm tails to heads in mouse.

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2012: Hitoshi Tainaka; Hikari Takahashi; Yoshitake Nishimune; Shigeru Oshio; Hiromitsu Tanaka; Masakazu Umezawa; Ken Takeda
Evaluation of the testicular toxicity of prenatal exposure to bisphenol A based on microarray analysis combined with MeSH annotation.
The Journal of toxicological sciences 2012;37(3):539-48.
2011: Hikari Takahashi; Ken Takeda; Hiromitsu Tanaka; Masakazu Umezawa; Yoshitake Nishimune; Hitoshi Tainaka; Shigeru Oshio
Evaluation of testicular toxicology of doxorubicin based on microarray analysis of testicular specific gene expression.
The Journal of toxicological sciences 2011;36(5):559-67.
2009: Keizo Tokuhiro; Ayako Isotani; Sadaki Yokota; Yoshihisa Yano; Shigeru Oshio; Mika Hirose; Morimasa Wada; Kyoko Fujita; Yukiko Ogawa; Masaru Okabe; Yoshitake Nishimune; Hiromitsu Tanaka
OAZ-t/OAZ3 is essential for rigid connection of sperm tails to heads in mouse.
PLoS genetics 2009;5(11):e1000712.
2009: Tomohiro Ueda; Hiroyuki Manabe; Keizo Tokuhiro; Mika Hirose; Yasuhiro Matsuoka; Yasushi Miyagawa; Akira Tsujimura; Kyoko Fujita; Morimasa Wada; Akihiko Okuyama; Yoshitake Nishimune; Hiromitsu Tanaka
Unique alternative translation from two open reading frames on Acpin1 mRNA yields an acrosomal protein and a salivary-gland-specific protein.
International journal of urology : official journal of the Japanese Urological Association 2009;16(7):639-46.
2009: Shinji Irie; Akira Tsujimura; Yasushi Miyagawa; Tomohiro Ueda; Yasuhiro Matsuoka; Yasuhisa Matsui; Akihiko Okuyama; Yoshitake Nishimune; Hiromitsu Tanaka
Single-nucleotide polymorphisms of the PRDM9 (MEISETZ) gene in patients with nonobstructive azoospermia.
Journal of andrology 2009;30(4):426-31.
2008: H Nakane; Seiichi Hirota; Philip J Brooks; Yusaku Nakabeppu; Yoshimichi Nakatsu; Yoshitake Nishimune; Akihiro Iino; Kiyoji Tanaka
Impaired spermatogenesis and elevated spontaneous tumorigenesis in xeroderma pigmentosum group A gene (Xpa)-deficient mice.
DNA repair 2008;7(12):1938-50.
2008: Keizo Tokuhiro; Mika Hirose; Yasushi Miyagawa; Akira Tsujimura; Shinji Irie; Ayako Isotani; Masaru Okabe; Yoshiro Toyama; Chizuru Ito; Kiyotaka Toshimori; Ken Takeda; Shigeru Oshio; Hitoshi Tainaka; Junji Tsuchida; Akihiko Okuyama; Yoshitake Nishimune; Hiromitsu Tanaka
Meichroacidin containing the membrane occupation and recognition nexus motif is essential for spermatozoa morphogenesis.
The Journal of biological chemistry 2008;283(27):19039-48.
2008: Yasuhiro Matsuoka; Yasushi Miyagawa; Keizo Tokuhiro; Kouichi Kitamura; Naoko Iguchi; Mamiko Maekawa; Tohru Takahashi; Akira Tsujimura; Kiyomi Matsumiya; Akihiko Okuyama; Yoshitake Nishimune; Hiromitsu Tanaka
Isolation and characterization of the spermatid-specific Smrp1 gene encoding a novel manchette protein.
Molecular reproduction and development 2008;75(6):967-75.
2008: Souichi A Iwai; Shigeki Amekawa; K Yomogida; T Sumi; Mitsuhiro Nakazawa; Yoshiaki Yura; Yoshitake Nishimune; M Nozaki
ESE-1 inhibits the invasion of oral squamous cell carcinoma in conjunction with MMP-9 suppression.
Oral diseases 2008;14(2):144-9.
2007: Akiko Ike; Keizo Tokuhiro; Mika Hirose; Masami Nozaki; Yoshitake Nishimune; Hiromitsu Tanaka
Comprehensive analysis of gene expression in testes producing haploid germ cells using DNA microarray analysis.
International journal of andrology 2007;30(5):462-75.
2007: Keizo Tokuhiro; Yasushi Miyagawa; Shuichi Yamada; Mika Hirose; Hiroshi Ohta; Yoshitake Nishimune; Hiromitsu Tanaka
The 193-base pair Gsg2 (haspin) promoter region regulates germ cell-specific expression bidirectionally and synchronously.
Biology of reproduction 2007;76(3):407-14.
2007: Hiromitsu Tanaka; Mika Hirose; Keizo Tokuhiro; Y Matsuoka; Yasushi Miyagawa; A Tsujimura; A Okuyama; Yoshitake Nishimune
Single nucleotide polymorphisms: discovery of the genetic causes of male infertility.
Society of Reproduction and Fertility supplement 2007;65():531-4.
2006: Peter Fraisl; Hiromitsu Tanaka; Sonja Forss-Petter; Hans Lassmann; Yoshitake Nishimune; Johannes Berger
A novel mammalian bubblegum-related acyl-CoA synthetase restricted to testes and possibly involved in spermatogenesis.
Archives of biochemistry and biophysics 2006;451(1):23-33.
2006: Yoshitake Nishimune; Hiromitsu Tanaka
Infertility caused by polymorphisms or mutations in spermatogenesis-specific genes.
Journal of andrology 2006;27(3):326-34.
2006: Hiromitsu Tanaka; Yasuhiro Matsuoka; Masayoshi Onishi; Kouichi Kitamura; Yasushi Miyagawa; Hiromi Nishimura; Akira Tsujimura; Akihiko Okuyama; Yoshitake Nishimune
Expression profiles and single-nucleotide polymorphism analysis of human HANP1/H1T2 encoding a histone H1-like protein.
International journal of andrology 2006;29(2):353-9.
2006: Makoto Tsuneoka; Yoshitake Nishimune; Keisuke Ohta; Kwesi Teye; Hiromitsu Tanaka; Mikiko Soejima; Hiroshi Iida; Tetsuo Inokuchi; Hiroshi Kimura; Yoshiro Koda
Expression of Mina53, a product of a Myc target gene in mouse testis.
International journal of andrology 2006;29(2):323-30.
2005: Kouichi Kitamura; Hiromitsu Tanaka; Yoshitake Nishimune
The RING-finger protein haprin: domains and function in the acrosome reaction.
Current protein & peptide science 2005;6(6):567-74.
2005: Yasushi Miyagawa; Hiromi Nishimura; Akira Tsujimura; Yasuhiro Matsuoka; Kiyomi Matsumiya; Akihiko Okuyama; Yoshitake Nishimune; Hiromitsu Tanaka
Single-nucleotide polymorphisms and mutation analyses of the TNP1 and TNP2 genes of fertile and infertile human male populations.
Journal of andrology 2005;26(6):779-86.
2005: Sadaharu Masuyama; Satoshi Tateishi; Kentaro Yomogida; Yoshitake Nishimune; Keiichiro Suzuki; Yoshiyuki Sakuraba; Hirokazu Inoue; Michio Ogawa; Masaru Yamaizumi
Regulated expression and dynamic changes in subnuclear localization of mammalian Rad18 under normal and genotoxic conditions.
Genes to cells : devoted to molecular & cellular mechanisms 2005;10(8):753-62.
2005: Hiromitsu Tanaka; Naoko Iguchi; Ayako Isotani; Kouichi Kitamura; Yoshiro Toyama; Yasuhiro Matsuoka; Masayoshi Onishi; Kumiko Masai; Mamiko Maekawa; Kiyotaka Toshimori; Masaru Okabe; Yoshitake Nishimune
HANP1/H1T2, a novel histone H1-like protein involved in nuclear formation and sperm fertility.
Molecular and cellular biology 2005;25(16):7107-19.
2005: Kouichi Kitamura; Hiromi Nishimura; Yoshitake Nishimune; Hiromitsu Tanaka
Identification of human HAPRIN potentially involved in the acrosome reaction.
Journal of andrology 2005;26(4):511-8.
2005: Ippei Nagamori; Norikazu Yabuta; Takayuki Fujii; Hiromitsu Tanaka; Kentaro Yomogida; Yoshitake Nishimune; Hiroshi Nojima
Tisp40, a spermatid specific bZip transcription factor, functions by binding to the unfolded protein response element via the Rip pathway.
Genes to cells : devoted to molecular & cellular mechanisms 2005;10(6):575-94.
2005: Masafumi Ihara; Ayae Kinoshita; Shuichi Yamada; Hiromitsu Tanaka; Ai Tanigaki; Ayumi Kitano; Motohito Goto; Kazutoshi Okubo; Hiroyuki Nishiyama; Osamu Ogawa; Chiaki Takahashi; Shigeyoshi Itohara; Yoshitake Nishimune; Makoto Noda; Makoto Kinoshita
Cortical organization by the septin cytoskeleton is essential for structural and mechanical integrity of mammalian spermatozoa.
Developmental cell 2005;8(3):343-52.
2005: Pranee Somboonthum; Hiroshi Ohta; Shuichi Yamada; Masayoshi Onishi; Akiko Ike; Yoshitake Nishimune; Masami Nozaki
cAMP-responsive element in TATA-less core promoter is essential for haploid-specific gene expression in mouse testis.
Nucleic acids research 2005;33(10):3401-11.
2004: Kouichi Kitamura; Naoko Iguchi; Yoshioki Kaneko; Hiromitsu Tanaka; Yoshitake Nishimune
Characterization of a novel postacrosomal perinuclear theca-specific protein, CYPT1.
Biology of reproduction 2004;71(6):1927-35.
2004: Kélen F Arrotéia; Paulo P Joazeiro; Aureo T Yamada; Hiromitsu Tanaka; Yoshitake Nishimune; Luís A V Pereira
Identification and characterization of an antigen recognized by monoclonal antibody TRA 54 in mouse epididymis and vas deferens.
Journal of andrology 2004;25(6):914-21.
2004: Hiromitsu Tanaka; Naoko Iguchi; Yoshiro Toyama; Kouichi Kitamura; Tohru Takahashi; Kazuhiro Kaseda; Mamiko Maekawa; Yoshitake Nishimune
Mice deficient in the axonemal protein Tektin-t exhibit male infertility and immotile-cilium syndrome due to impaired inner arm dynein function.
Molecular and cellular biology 2004;24(18):7958-64.
2004: Hiromitsu Tanaka; Tohru Takahashi; Naoko Iguchi; Kouichi Kitamura; Yasushi Miyagawa; Akira Tsujimura; Kiyomi Matsumiya; Akihiko Okuyama; Yoshitake Nishimune
Ketone bodies could support the motility but not the acrosome reaction of mouse sperm.
International journal of andrology 2004;27(3):172-7.
2004: Yasuhiro Matsuoka; Naoko Iguchi; Kouichi Kitamura; Hiromi Nishimura; Hiroyuki Manabe; Yasushi Miyagawa; Minoru Koga; Kiyomi Matsumiya; Akihiko Okuyama; Hiromitsu Tanaka; Yoshitake Nishimune
Cloning and characterization of a mouse spergen-1 localized in sperm mitochondria.
International journal of andrology 2004;27(3):152-60.
2004: Toshiyuki Habu; Nobunao Wakabayashi; Kayo Yoshida; Kentaro Yomogida; Yoshitake Nishimune; Takashi Morita
p53 Protein interacts specifically with the meiosis-specific mammalian RecA-like protein DMC1 in meiosis.
Carcinogenesis 2004;25(6):889-93.
2004: Tohru Takahashi; Hiromitsu Tanaka; Naoko Iguchi; Kouichi Kitamura; Yily Chen; Mamiko Maekawa; Hiromi Nishimura; Hiroshi Ohta; Yasushi Miyagawa; Kiyomi Matsumiya; Akihiko Okuyama; Yoshitake Nishimune
Rosbin: a novel homeobox-like protein gene expressed exclusively in round spermatids.
Biology of reproduction 2004;70(5):1485-92.
2004: Naoko Iguchi; Hiromitsu Tanaka; Shuichi Yamada; Hiromi Nishimura; Yoshitake Nishimune
Control of mouse hils1 gene expression during spermatogenesis: identification of regulatory element by transgenic mouse.
Biology of reproduction 2004;70(5):1239-45.
2004: Hiroshi Ohta; Teruhiko Wakayama; Yoshitake Nishimune
Commitment of fetal male germ cells to spermatogonial stem cells during mouse embryonic development.
Biology of reproduction 2004;70(5):1286-91.
2004: Masayoshi Onishi; Teruo Yasunaga; Hiromitsu Tanaka; Yoshitake Nishimune; Masami Nozaki
Gene structure and evolution of testicular haploid germ cell-specific genes, Oxct2a and Oxct2b.
Genomics 2004;83(4):647-57.
2004: Akiko Ike; Hiroshi Ohta; Masayoshi Onishi; Naoko Iguchi; Yoshitake Nishimune; Masami Nozaki
Transient expression analysis of the mouse ornithine decarboxylase antizyme haploid-specific promoter using in vivo electroporation.
FEBS letters 2004;559(1-3):159-64.
2004: T Imai; Y Kawai; Yuko Tadokoro; M Yamamoto; Yoshitake Nishimune; Kentaro Yomogida
In vivo and in vitro constant expression of GATA-4 in mouse postnatal Sertoli cells.
Molecular and cellular endocrinology 2004;214(1-2):107-15.
2003: Naoko Iguchi; Hiromitsu Tanaka; Kentaro Yomogida; Yoshitake Nishimune
Isolation and characterization of a novel cDNA encoding a DNA-binding protein (Hils1) specifically expressed in testicular haploid germ cells.
International journal of andrology 2003;26(6):354-65.
2003: Hiroshi Ohta; Akira Tohda; Yoshitake Nishimune
Proliferation and differentiation of spermatogonial stem cells in the w/wv mutant mouse testis.
Biology of reproduction 2003;69(6):1815-21.
2003: Kouichi Kitamura; Hiromitsu Tanaka; Yoshitake Nishimune
Haprin, a novel haploid germ cell-specific RING finger protein involved in the acrosome reaction.
The Journal of biological chemistry 2003;278(45):44417-23.
2003: Kentaro Yomogida; Yo Yagura; Yuko Tadokoro; Yoshitake Nishimune
Dramatic expansion of germinal stem cells by ectopically expressed human glial cell line-derived neurotrophic factor in mouse Sertoli cells.
Biology of reproduction 2003;69(4):1303-7.
2003: Yuko Tadokoro; Kentaro Yomogida; Yo Yagura; Shuichi Yamada; Masaru Okabe; Yoshitake Nishimune
Characterization of histone H2A.X expression in testis and specific labeling of germ cells at the commitment stage of meiosis with histone H2A.X promoter-enhanced green fluorescent protein transgene.
Biology of reproduction 2003;69(4):1325-9.
2003: Hideki Tani; Chang Kwang Limn; Chan Choo Yap; Masayoshi Onishi; Masami Nozaki; Yoshitake Nishimune; Nobuo Okahashi; Yoshinori Kitagawa; Rie Watanabe; Rika Mochizuki; Kohji Moriishi; Yoshiharu Matsuura
In vitro and in vivo gene delivery by recombinant baculoviruses.
Journal of virology 2003;77(18):9799-808.
2003: Mizue Hisano; Hiroshi Ohta; Yoshitake Nishimune; Masami Nozaki
Methylation of CpG dinucleotides in the open reading frame of a testicular germ cell-specific intronless gene, Tact1/Actl7b, represses its expression in somatic cells.
Nucleic acids research 2003;31(16):4797-804.
2003: Hiromitsu Tanaka; Naoko Iguchi; Carlos Egydio de Carvalho; Yuko Tadokoro; Kentaro Yomogida; Yoshitake Nishimune
Novel actin-like proteins T-ACTIN 1 and T-ACTIN 2 are differentially expressed in the cytoplasm and nucleus of mouse haploid germ cells.
Biology of reproduction 2003;69(2):475-82.
2003: Shin-ichi Sakata; Kazuhiro Sakamaki; Ken-ichiro Watanabe; N Nakamura; Shinya Toyokuni; Yoshitake Nishimune; Chisato Mori; Shin Yonehara
Involvement of death receptor Fas in germ cell degeneration in gonads of Kit-deficient Wv/Wv mutant mice.
Cell death and differentiation 2003;10(6):676-86.
2003: Mizue Hisano; Shuichi Yamada; Hiromitsu Tanaka; Yoshitake Nishimune; Masami Nozaki
Genomic structure and promoter activity of the testis haploid germ cell-specific intronless genes, Tact1 and Tact2.
Molecular reproduction and development 2003;65(2):148-56.
2003: Hiroshi Ohta; Shinichi Aizawa; Yoshitake Nishimune
Functional analysis of the p53 gene in apoptosis induced by heat stress or loss of stem cell factor signaling in mouse male germ cells.
Biology of reproduction 2003;68(6):2249-54.
2003: Kouichi Kitamura; Yasushi Miyagawa; Naoko Iguchi; Hiromi Nishimura; Hiromitsu Tanaka; Yoshitake Nishimune
Molecular cloning and characterization of the human orthologue of the oppo 1 gene encoding a sperm tail protein.
Molecular human reproduction 2003;9(5):237-43.
2003: Junji Tsuchida; Kayoko Dohmae; Yukihiko Kitamura; Yoshitake Nishimune
The role of the c-kit receptor in the regenerative differentiation of rat Leydig cells.
International journal of andrology 2003;26(2):121-5.
2003: Mitsuhiro Kashiwaba; Koji Katsura; Motoko Ohnishi; Mutsuo Sasaki; Hiromitsu Tanaka; Yoshitake Nishimune; Takayasu Kobayashi; Shinri Tamura
A novel protein phosphatase 2C family member (PP2Czeta) is able to associate with ubiquitin conjugating enzyme 9.
FEBS letters 2003;538(1-3):197-202.
2003: Hiromitsu Tanaka; Yasushi Miyagawa; Akira Tsujimura; Kiyomi Matsumiya; Akihiko Okuyama; Yoshitake Nishimune
Single nucleotide polymorphisms in the protamine-1 and -2 genes of fertile and infertile human male populations.
Molecular human reproduction 2003;9(2):69-73.
2003: Hiromitsu Tanaka; Naoko Iguchi; Yasushi Miyagawa; Minoru Koga; Junya Kohroki; Yoshitake Nishimune
Differential expression of succinyl CoA transferase (SCOT) genes in somatic and germline cells of the mouse testis.
International journal of andrology 2003;26(1):52-6.
2002: Keiji Sato; Kentaro Yomogida; Takayuki Wada; Tetuya Yorihuzi; Yoshitake Nishimune; Nobuko Hosokawa; Kazuhiro Nagata
Type XXVI collagen, a new member of the collagen family, is specifically expressed in the testis and ovary.
The Journal of biological chemistry 2002;277(40):37678-84.
2002: Akiko Ike; Shuich Yamada; Hiromitsu Tanaka; Yoshitake Nishimune; Masami Nozaki
Structure and promoter activity of the gene encoding ornithine decarboxylase antizyme expressed exclusively in haploid germ cells in testis (OAZt/Oaz3).
Gene 2002;298(2):183-93.
2002: Kentaro Yomogida; Yo Yagura; Yoshitake Nishimune
Electroporated transgene-rescued spermatogenesis in infertile mutant mice with a sertoli cell defect.
Biology of reproduction 2002;67(3):712-7.
2002: Kumi Ozaki-Kuroda; Hiroyuki Nakanishi; Hiroshi Ohta; Hiromitsu Tanaka; Hidetake Kurihara; Steffen Mueller; Kenji Irie; Wataru Ikeda; Tatsuo Sakai; Eckard Wimmer; Yoshitake Nishimune; Yoshimi Takai
Nectin couples cell-cell adhesion and the actin scaffold at heterotypic testicular junctions.
Current biology : CB 2002;12(13):1145-50.
2002: Yoshihiro Nakamura; Hiromitsu Tanaka; Minoru Koga; Yasushi Miyagawa; Naoko Iguchi; Carlos Egydio de Carvalho; Kentaro Yomogida; Masami Nozaki; Hiroshi Nojima; Kiyomi Matsumiya; Akihiko Okuyama; Yoshitake Nishimune
Molecular cloning and characterization of oppo 1: a haploid germ cell-specific complementary DNA encoding sperm tail protein.
Biology of reproduction 2002;67(1):1-7.
2002: Kiyoko Tanaka; Hiroshi Tamura; Hiromitsu Tanaka; Masaki Katoh; Yoshiki Futamata; Naohiko Seki; Yoshitake Nishimune; Takahiko Hara
Spermatogonia-dependent expression of testicular genes in mice.
Developmental biology 2002;246(2):466-79.
2002: Yasushi Miyagawa; Hiromitsu Tanaka; Naoko Iguchi; Kouichi Kitamura; Yoshihiro Nakamura; Tohru Takahashi; Kiyomi Matsumiya; Akihiko Okuyama; Yoshitake Nishimune
Molecular cloning and characterization of the human orthologue of male germ cell-specific actin capping protein alpha3 (cpalpha3).
Molecular human reproduction 2002;8(6):531-9.
2002: Naoko Iguchi; Hiromitsu Tanaka; Yoshihiro Nakamura; Masami Nozaki; Tsutomu Fujiwara; Yoshitake Nishimune
Cloning and characterization of the human tektin-t gene.
Molecular human reproduction 2002;8(6):525-30.
2002: Sami Ventelä; Hiroshi Ohta; Martti Parvinen; Yoshitake Nishimune
Development of the stages of the cycle in mouse seminiferous epithelium after transplantation of green fluorescent protein-labeled spermatogonial stem cells.
Biology of reproduction 2002;66(5):1422-9.
2002: Takayuki Fujii; Kazutoshi Tamura; Kumiko Masai; Hiromitsu Tanaka; Yoshitake Nishimune; Hiroshi Nojima
Use of stepwise subtraction to comprehensively isolate mouse genes whose transcription is up-regulated during spermiogenesis.
EMBO reports 2002;3(4):367-72.
2002: Yuko Tadokoro; Kentaro Yomogida; Hiroshi Ohta; Akira Tohda; Yoshitake Nishimune
Homeostatic regulation of germinal stem cell proliferation by the GDNF/FSH pathway.
Mechanisms of development 2002;113(1):29-39.
2002: Carlos Egydio de Carvalho; Hiromitsu Tanaka; Naoko Iguchi; Sami Ventelä; Hiroshi Nojima; Yoshitake Nishimune
Molecular cloning and characterization of a complementary DNA encoding sperm tail protein SHIPPO 1.
Biology of reproduction 2002;66(3):785-95.
2002: Toshihide Doi; Takashi Morita; Nobunao Wakabayashi; Tetsuro Sumi; Souichi A Iwai; Shigeki Amekawa; Masayoshi Sakuda; Yoshitake Nishimune
Induction of instability of p34(cdc2) expression by treatment with cisplatin (CDDP) in mouse teratocarcinoma F9 cells.
Cancer letters 2002;176(1):75-80.
2002: Hiromitsu Tanaka; Junya Kohroki; Naoko Iguchi; Masayoshi Onishi; Yoshitake Nishimune
Cloning and characterization of a human orthologue of testis-specific succinyl CoA: 3-oxo acid CoA transferase (Scot-t) cDNA.
Molecular human reproduction 2002;8(1):16-23.
2002: Akira Tohda; Tsuyoshi Okuno; Kiyomi Matsumiya; Masaru Okabe; Hidefumi Kishikawa; Kayoko Dohmae; Akihiko Okuyama; Yoshitake Nishimune
Restoration of spermatogenesis and fertility in azoospermic mutant mice by suppression and reelevation of testosterone followed by intracytoplasmic sperm injection.
Biology of reproduction 2002;66(1):85-90.
2001: Masahito Ikawa; Tsuyoshi Nakanishi; S Yamada; I Wada; K Kominami; Hiromitsu Tanaka; Masami Nozaki; Yoshitake Nishimune; Masaru Okabe
Calmegin is required for fertilin alpha/beta heterodimerization and sperm fertility.
Developmental biology 2001;240(1):254-61.
2001: Holly L Boettger-Tong; Jan Rohozinski; Alexander I Agoulnik; Kayoko Dohmae; Yoshitake Nishimune; N Levy; Jack alvarez
Identification and sequencing the juvenile spermatogonial depletion critical interval on mouse chromosome 1 reveals the presence of eight candidate genes.
Biochemical and biophysical research communications 2001;288(5):1129-35.
2001: Akira Tohda; Kiyomi Matsumiya; Yuko Tadokoro; Kentaro Yomogida; Yasushi Miyagawa; Kayoko Dohmae; Akihiko Okuyama; Yoshitake Nishimune
Testosterone suppresses spermatogenesis in juvenile spermatogonial depletion (jsd ) mice.
Biology of reproduction 2001;65(2):532-7.
2001: Y Yoshimura; Hiromitsu Tanaka; Masami Nozaki; Kentaro Yomogida; Teruo Yasunaga; Yoshitake Nishimune
Nested genomic structure of haploid germ cell specific haspin gene.
Gene 2001;267(1):49-54.
2001: Hiromitsu Tanaka; Naoko Iguchi; Yusuke Nakamura; Junya Kohroki; C E de Carvalho; Yoshitake Nishimune
Cloning and characterization of human haspin gene encoding haploid germ cell-specific nuclear protein kinase.
Molecular human reproduction 2001;7(3):211-8.
2001: Hideaki Ohta; Kentaro Yomogida; Yuko Tadokoro; Akira Tohda; Kayoko Dohmae; Yoshitake Nishimune
Defect in germ cells, not in supporting cells, is the cause of male infertility in the jsd mutant mouse: proliferation of spermatogonial stem cells without differentiation.
International journal of andrology 2001;24(1):15-23.
2000: Sami Ventelä; Mika Mulari; M Okabe; Hiromitsu Tanaka; Yoshitake Nishimune; Jorma Toppari; Martti Parvinen
Regulation of acrosome formation in mice expressing green fluorescent protein as a marker.
Tissue & cell 2000;32(6):501-7.
2000: Nobunao Wakabayashi; R Kageyama; Toshiyuki Habu; Takefumi Doi; Takashi Morita; Masami Nozaki; Masaki Yamamoto; Yoshitake Nishimune
A novel cis-acting element regulates HES-1 gene expression in P19 embryonal carcinoma cells treated with retinoic acid.
Journal of biochemistry 2000;128(6):1087-95.
2000: Minoru Koga; Hiromitsu Tanaka; Kentaro Yomogida; Masami Nozaki; Junji Tsuchida; Hiroshi Ohta; Yoshihiro Nakamura; Kumiko Masai; Y Yoshimura; M Yamanaka; Naoko Iguchi; Hiroshi Nojima; Kiyomi Matsumiya; Akihiko Okuyama; Yoshitake Nishimune
Isolation and characterization of a haploid germ cell-specific novel complementary deoxyribonucleic acid; testis-specific homologue of succinyl CoA:3-Oxo acid CoA transferase.
Biology of reproduction 2000;63(6):1601-9.
2000: K Uchida; Junji Tsuchida; Hiromitsu Tanaka; Minoru Koga; Yuko Nishina; Masami Nozaki; K Yoshinaga; Kiyotaka Toshimori; Kiyomi Matsumiya; Akihiko Okuyama; Yoshitake Nishimune
Cloning and characterization of a complementary deoxyribonucleic acid encoding haploid-specific alanine-rich acidic protein located on chromosome-X.
Biology of reproduction 2000;63(4):993-9.
2000: Sami Ventelä; M Okabe; Hiromitsu Tanaka; Yoshitake Nishimune; Jorma Toppari; Martti Parvinen
Expression of green fluorescent protein under beta-actin promoter in living spermatogenic cells of the mouse: stage-specific regulation by FSH.
International journal of andrology 2000;23(4):236-42.
2000: M Yamanaka; Minoru Koga; Hiromitsu Tanaka; Yoshihiro Nakamura; Hiroshi Ohta; Kentaro Yomogida; Junji Tsuchida; Naoko Iguchi; Hiroshi Nojima; Masami Nozaki; Kiyomi Matsumiya; Akihiko Okuyama; Kiyotaka Toshimori; Yoshitake Nishimune
Molecular cloning and characterization of phosphatidylcholine transfer protein-like protein gene expressed in murine haploid germ cells.
Biology of reproduction 2000;62(6):1694-1701.
2000: Hideaki Ohta; Kentaro Yomogida; Kayoko Dohmae; Yoshitake Nishimune
Regulation of proliferation and differentiation in spermatogonial stem cells: the role of c-kit and its ligand SCF.
Development (Cambridge, England) 2000;127(10):2125-31.
2000: Y Tosaka; Hiromitsu Tanaka; Yoshihisa Yano; Kumiko Masai; Masami Nozaki; Kentaro Yomogida; S Otani; Hiroshi Nojima; Yoshitake Nishimune
Identification and characterization of testis specific ornithine decarboxylase antizyme (OAZ-t) gene: expression in haploid germ cells and polyamine-induced frameshifting.
Genes to cells : devoted to molecular & cellular mechanisms 2000;5(4):265-76.
2000: X Ling; Hiromitsu Tanaka; Junji Tsuchida; Yoshitake Nishimune
Identification of differentiation antigens in mouse testicular germ cells recognized by monoclonal antibody TRA 55.
International journal of andrology 2000;23(1):29-35.
2000: Norikazu Yabuta; T Fujii; Neal G Copeland; DJ Gilbert; NA Jenkins; H Nishiguchi; Y Endo; Shingo Toji; Hiromitsu Tanaka; Yoshitake Nishimune; Hiroshi Nojima
Structure, expression, and chromosome mapping of LATS2, a mammalian homologue of the Drosophila tumor suppressor gene lats/warts.
Genomics 2000;63(2):263-70.
1999: Kiyomi Matsumiya; Marvin L Meistrich; G Shetty; Kayoko Dohmae; Akira Tohda; Akihiko Okuyama; Yoshitake Nishimune
Stimulation of spermatogonial differentiation in juvenile spermatogonial depletion (jsd) mutant mice by gonadotropin-releasing hormone antagonist treatment.
Endocrinology 1999;140(10):4912-5.
1999: Y Yoshimura; Hiromitsu Tanaka; Masami Nozaki; Kentaro Yomogida; K Shimamura; Teruo Yasunaga; Yoshitake Nishimune
Genomic analysis of male germ cell-specific actin capping protein alpha.
Gene 1999;237(1):193-9.
1999: T Kuroda; Hiromitsu Tanaka; Hitomi Nakamura; Yoshitake Nishimune; Tadamitsu Kishimoto
Hepatoma-derived growth factor-related protein (HRP)-1 gene in spermatogenesis in mice.
Biochemical and biophysical research communications 1999;262(2):433-7.
1999: Naoko Iguchi; Hiromitsu Tanaka; Tsuneko Fujii; K Tamura; Y Kaneko; Hiroshi Nojima; Yoshitake Nishimune
Molecular cloning of haploid germ cell-specific tektin cDNA and analysis of the protein in mouse testis.
FEBS letters 1999;456(2):315-21.
1999: Hiromitsu Tanaka; Y Yoshimura; Masami Nozaki; Kentaro Yomogida; Junji Tsuchida; Y Tosaka; Toshiyuki Habu; T Nakanishi; Masato Okada; Hiroshi Nojima; Yoshitake Nishimune
Identification and characterization of a haploid germ cell-specific nuclear protein kinase (Haspin) in spermatid nuclei and its effects on somatic cells.
The Journal of biological chemistry 1999;274(24):17049-57.
1999: Tsuyoshi Nakanishi; Masahito Ikawa; S Yamada; M Parvinen; T Baba; Yoshitake Nishimune; Masaru Okabe
Real-time observation of acrosomal dispersal from mouse sperm using GFP as a marker protein.
FEBS letters 1999;449(2-3):277-83.
1999: T Fujii; K Tamura; Neal G Copeland; DJ Gilbert; NA Jenkins; Kentaro Yomogida; Hiromitsu Tanaka; Yoshitake Nishimune; Hiroshi Nojima; Y Abiko
Sperizin is a murine RING zinc-finger protein specifically expressed in Haploid germ cells.
Genomics 1999;57(1):94-101.
1998: Nicolas Lévy; Holly L Boettger-Tong; Kayoko Dohmae; Alexander I Agoulnik; T I Ty; Yoshitake Nishimune; Jack alvarez
Physical and genetic linkage of glutaminase (Gls), signal transducer and activator of transcription 1 (Stat1), and xeroderma pigmentosum complementation group G (Xpg) on mouse proximal chromosome 1.
Genomics 1998;54(2):355-6.
1998: Kayoko Dohmae; Yoshitake Nishimune
Maternal transfer of Hantavirus antibodies in rats.
Laboratory animal science 1998;48(4):395-7.
1998: Junji Tsuchida; Yuko Nishina; Nobunao Wakabayashi; Masami Nozaki; Yasuo Sakai; Yoshitake Nishimune
Molecular cloning and characterization of meichroacidin (male meiotic metaphase chromosome-associated acidic protein).
Developmental biology 1998;197(1):67-76.
1998: Kayo Yoshida; Gen Kondoh; Y Matsuda; Toshiyuki Habu; Yoshitake Nishimune; Takashi Morita
The mouse RecA-like gene Dmc1 is required for homologous chromosome synapsis during meiosis.
Molecular cell 1998;1(5):707-18.
1998: Kentaro Yomogida; Yoshitake Nishimune
[Spermatogenesis in mammalian testis].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1998;43(4):511-21.
1998: Minoru Koga; Hiromitsu Tanaka; Kentaro Yomogida; Junji Tsuchida; K Uchida; M Kitamura; S Sakoda; Kiyomi Matsumiya; Akihiko Okuyama; Yoshitake Nishimune
Expression of selenoprotein-P messenger ribonucleic acid in the rat testis.
Biology of reproduction 1998;58(1):261-5.
1997: Hiromitsu Tanaka; Masahito Ikawa; Junji Tsuchida; Masami Nozaki; Miwako Suzuki; Taku Fujiwara; Masaru Okabe; Yoshitake Nishimune
Cloning and characterization of the human Calmegin gene encoding putative testis-specific chaperone.
Gene 1997;204(1-2):159-63.
1997: Hiromitsu Tanaka; L A Pereira; Masami Nozaki; Junji Tsuchida; K Sawada; H Mori; Yoshitake Nishimune
A germ cell-specific nuclear antigen recognized by a monoclonal antibody raised against mouse testicular germ cells.
International journal of andrology 1997;20(6):361-6.
1997: Makoto M Taketo; Y Araki; A Matsunaga; A Yokoi; Junji Tsuchida; Yuko Nishina; Masami Nozaki; Hiromitsu Tanaka; M Koga; K Uchida; K Matsumiya; A Okuyama; JM Rochelle; Yoshitake Nishimune; Minoru MATSUI; Michael F Seldin
Mapping of eight testis-specific genes to mouse chromosomes.
Genomics 1997;46(1):138-42.
1997: Gen Kondoh; Kentaro Yomogida; Kayoko Dohmae; M Nozawa; Minoru Koga; Norio Nonomura; Tsuneharu Miki; Akihiko Okuyama; Yoshitake Nishimune
Coexpression of multiple Sertoli cell and Leydig cell marker genes in the spontaneous testicular tumor of F344 rat: evidence for phenotypical bifurcation of the interstitial cell tumor.
Japanese journal of cancer research : Gann 1997;88(9):839-45.
1997: Y Kojima; K Kominami; Kayoko Dohmae; Norio Nonomura; Tsuneharu Miki; Akihiko Okuyama; Yoshitake Nishimune; Masaru Okabe
Cessation of spermatogenesis in juvenile spermatogonial depletion (jsd/jsd) mice.
International journal of urology : official journal of the Japanese Urological Association 1997;4(5):500-7.
1997: Masahito Ikawa; I Wada; K Kominami; D Watanabe; Kiyotaka Toshimori; Yoshitake Nishimune; Masaru Okabe
The putative chaperone calmegin is required for sperm fertility.
Nature 1997;387(6633):607-11.
1997: Masaru Okabe; Masahito Ikawa; K Kominami; Tsuyoshi Nakanishi; Yoshitake Nishimune
'Green mice' as a source of ubiquitous green cells.
FEBS letters 1997;407(3):313-9.
1997: Shuji Miyagawa; Shoki Mikata; Hiromitsu Tanaka; Masahito Ikawa; K Kominami; Tsukasa Seya; Yoshitake Nishimune; Ryota Shirakura; Masaru Okabe
The regulation of membrane cofactor protein (CD46) expression by the 3' untranslated region in transgenic mice.
Biochemical and biophysical research communications 1997;233(3):829-33.
1997: N Kondoh; Yuko Nishina; Junji Tsuchida; Minoru Koga; Hiromitsu Tanaka; K Uchida; Johji Inazawa; Makoto M Taketo; Masami Nozaki; Hiroshi Nojima; Kiyomi Matsumiya; M Namiki; Akihiko Okuyama; Yoshitake Nishimune
Assignment of synaptonemal complex protein 1 (SCP1) to human chromosome 1p13 by fluorescence in situ hybridization and its expression in the testis.
Cytogenetics and cell genetics 1997;78(2):103-4.
1997: Minoru MATSUI; H Ichihara; S Kobayashi; Hiromitsu Tanaka; Junji Tsuchida; Masami Nozaki; Y Yoshimura; Hiroshi Nojima; JM Rochelle; Yoshitake Nishimune; Makoto M Taketo; Michael F Seldin
Mapping of six germ-cell-specific genes to mouse chromosomes.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(11):873-4.
1996: Q Li; Gen Kondoh; S Inafuku; Yoshitake Nishimune; Akira Hakura
Abrogation of c-kit/Steel factor-dependent tumorigenesis by kinase defective mutants of the c-kit receptor: c-kit kinase defective mutants as candidate tools for cancer gene therapy.
Cancer research 1996;56(19):4343-6.
1996: A Yamamoto; T Taki; H Yagi; Toshiyuki Habu; Ken-Ichi Yoshida; Y Yoshimura; K Yamamoto; A Matsushiro; Yoshitake Nishimune; T Morita
Cell cycle-dependent expression of the mouse Rad51 gene in proliferating cells.
Molecular & general genetics : MGG 1996;251(1):1-12.
1996: Toshiyuki Habu; T Taki; A West; Yoshitake Nishimune; T Morita
The mouse and human homologs of DMC1, the yeast meiosis-specific homologous recombination gene, have a common unique form of exon-skipped transcript in meiosis.
Nucleic acids research 1996;24(3):470-7.
1995: H Aoto; Junji Tsuchida; Yuko Nishina; Yoshitake Nishimune; A Asano; Shoji Tajima
Isolation of a novel cDNA that encodes a protein localized to the pre-acrosome region of spermatids.
European journal of biochemistry / FEBS 1995;234(1):8-15.
1995: Masahito Ikawa; K Kominami; Y Yoshimura; K Tanaka; Yoshitake Nishimune; Masaru Okabe
A rapid and non-invasive selection of transgenic embryos before implantation using green fluorescent protein (GFP).
FEBS letters 1995;375(1-2):125-8.
1995: H Yagi; T Kato; T Nagata; Toshiyuki Habu; Masami Nozaki; A Matsushiro; Yoshitake Nishimune; T Morita
Regulation of the mouse histone H2A.X gene promoter by the transcription factor E2F and CCAAT binding protein.
The Journal of biological chemistry 1995;270(32):18759-65.
1995: Junji Tsuchida; Yuko Nishina; T Akamatsu; Yoshitake Nishimune
Characterization of development-specific, cell type-specific mouse testicular antigens using testis-specific polyclonal antibodies.
International journal of andrology 1995;18(4):208-12.
1995: D Watanabe; Masaru Okabe; N Hamajima; T Morita; Yuko Nishina; Yoshitake Nishimune
Characterization of the testis-specific gene 'calmegin' promoter sequence and its activity defined by transgenic mouse experiments.
FEBS letters 1995;368(3):509-12.
1995: S A Iwai; Yuko Nishina; M Kosaka; T Sumi; T Doi; Masayoshi Sakuda; Yoshitake Nishimune
The kinetics of induction of Hox1.6 and C-jun mRNA during three different ways of inducing differentiation in teratocarcinoma F9 cells.
In vitro cellular & developmental biology. Animal 1995;31(6):462-6.
1995: Yuko Nishina; T Sumi; S A Iwai; Yoshitake Nishimune
Effects of protein phosphatase inhibition by okadaic acid on the differentiation of F9 embryonal carcinoma cells.
Experimental cell research 1995;217(2):288-93.
1995: Y Tajima; D Watanabe; Uichi Koshimizu; T Matsuzawa; Yoshitake Nishimune
Insulin-like growth factor-I and transforming growth factor-alpha stimulate differentiation of type A spermatogonia in organ culture of adult mouse cryptorchid testes.
International journal of andrology 1995;18(1):8-12.
1995: Uichi Koshimizu; H Nishioka; D Watanabe; Kayoko Dohmae; Yoshitake Nishimune
Characterization of a novel spermatogenic cell antigen specific for early stages of germ cells in mouse testis.
Molecular reproduction and development 1995;40(2):221-7.
1995: Gen Kondoh; Naoto Hayasaka; Q Li; Yoshitake Nishimune; Akira Hakura
An in vivo model for receptor tyrosine kinase autocrine/paracrine activation: auto-stimulated KIT receptor acts as a tumor promoting factor in papillomavirus-induced tumorigenesis.
Oncogene 1995;10(2):341-7.
1995: T Doi; T Sumi; Yuko Nishina; M Kosaka; S A Iwai; Masayoshi Sakuda; Yoshitake Nishimune
Induction of teratocarcinoma F9 cell differentiation with cis-diammine dichloroplatinum(II) (CDDP).
Cancer letters 1995;88(1):81-6.
1995: Kayoko Dohmae; Yoshitake Nishimune
Protection against hantavirus infection by dam's immunity transferred vertically to neonates.
Archives of virology 1995;140(1):165-72.
1994: Kayoko Dohmae; Masaru Okabe; Yoshitake Nishimune
Experimental transmission of hantavirus infection in laboratory rats.
The Journal of infectious diseases 1994;170(6):1589-92.
1994: Gen Kondoh; Yoshitake Nishimune; Y Nishizawa; Naoto Hayasaka; K Matsumoto; Akira Hakura
Establishment and further characterization of a line of transgenic mice showing testicular tumorigenesis at 100% incidence.
The Journal of urology 1994;152(6 Pt 1):2151-4.
1994: H Tanaka; Y Yoshimura; Yuko Nishina; Masami Nozaki; Hiroshi Nojima; Yoshitake Nishimune
Isolation and characterization of cDNA clones specifically expressed in testicular germ cells.
FEBS letters 1994;355(1):4-10.
1994: Koji Isozaki; T Tsujimura; Shintaro Nomura; Eiichi Morii; Uichi Koshimizu; Yoshitake Nishimune; Y Kitamura
Cell type-specific deficiency of c-kit gene expression in mutant mice of mi/mi genotype.
The American journal of pathology 1994;145(4):827-36.
1994: Y Tajima; K Sawada; T Morimoto; Yoshitake Nishimune
Switching of mouse spermatogonial proliferation from the c-kit receptor-independent type to the receptor-dependent type during differentiation.
Journal of reproduction and fertility 1994;102(1):117-22.
1994: D Watanabe; K Yamada; Yuko Nishina; Y Tajima; Uichi Koshimizu; A Nagata; Yoshitake Nishimune
Molecular cloning of a novel Ca(2+)-binding protein (calmegin) specifically expressed during male meiotic germ cell development.
The Journal of biological chemistry 1994;269(10):7744-9.
1994: Uichi Koshimizu; T Tsujimura; Koji Isozaki; Shintaro Nomura; T Furitsu; Yuzuru Kanakura; Y Kitamura; Yoshitake Nishimune
Wn mutation of c-kit receptor affects its post-translational processing and extracellular expression.
Oncogene 1994;9(1):157-62.
1993: Kayoko Dohmae; Uichi Koshimizu; Yoshitake Nishimune
In utero and mammary transfer of hantavirus antibody from dams to infant rats.
Laboratory animal science 1993;43(6):557-61.
1993: Uichi Koshimizu; D Watanabe; K Sawada; Yoshitake Nishimune
A novel stage-specific differentiation antigen is expressed on mouse testicular germ cells during early meiotic prophase.
Biology of reproduction 1993;49(5):875-84.
1993: Y Tajima; Yuko Nishina; Uichi Koshimizu; Tomoko Jippo; Y Kitamura; Yoshitake Nishimune
Effects of hormones, cyclic AMP analogues and growth factors on steel factor (SF) production in mouse Sertoli cell cultures.
Journal of reproduction and fertility 1993;99(2):571-5.
1993: Yuko Nishina; T Sumi; S A Iwai; M Kosaka; Yoshitake Nishimune
The induction of jun genes during the reversible changes induced with sodium butyrate on the differentiation of F9 cells.
Experimental cell research 1993;208(2):492-7.
1993: M Namiki; N Kondoh; Kiyomi Matsumiya; S Sakoda; Yoshitake Nishimune; Akihiko Okuyama
Hormonal regulation of human testicular inhibin alpha and beta B subunit messenger RNAS.
The Journal of urology 1993;150(3):1007-9.
1993: T Tsujimura; Uichi Koshimizu; H Katoh; Koji Isozaki; Yuzuru Kanakura; T Tono; S Adachi; T Kasugai; H Tei; Yoshitake Nishimune
Mast cell number in the skin of heterozygotes reflects the molecular nature of c-kit mutation.
Blood 1993;81(10):2530-8.
1993: T Sumi; Yuko Nishina; M Kosaka; Masayoshi Sakuda; Yoshitake Nishimune
Suppression of tumorigenicity in temperature-sensitive mutants of embryonal carcinoma cells by induction of cell differentiation at non-permissive temperature.
International journal of cancer. Journal international du cancer 1993;54(2):333-7.
1993: S A Iwai; M Kosaka; Yuko Nishina; T Sumi; Masayoshi Sakuda; Yoshitake Nishimune
Changes in Hox1.6, c-jun, and Oct-3 gene expressions are associated with teratocarcinoma F9 cell differentiation in three different ways of induction.
Experimental cell research 1993;205(1):39-43.
1992: M Kosaka; S A Iwai; Yuko Nishina; T Sumi; Yoshitake Nishimune
c-myc and p53 gene expression in the differentiation of temperature-sensitive mutants of teratocarcinoma F9 cells.
Oncogene 1992;7(12):2455-60.
1992: D Watanabe; K Sawada; Uichi Koshimizu; T Kagawa; Yoshitake Nishimune
Characterization of male meiotic germ cell-specific antigen (Meg 1) by monoclonal antibody TRA 369 in mice.
Molecular reproduction and development 1992;33(3):307-12.
1992: T Tono; T Tsujimura; Uichi Koshimizu; T Kasugai; S Adachi; Koji Isozaki; S Nishikawa; M Morimoto; Yoshitake Nishimune; Shintaro Nomura
c-kit Gene was not transcribed in cultured mast cells of mast cell-deficient Wsh/Wsh mice that have a normal number of erythrocytes and a normal c-kit coding region.
Blood 1992;80(6):1448-53.
1992: Masatoshi Takeda; M Kosaka; Yuko Nishina; K Sawada; K Matsumoto; Yoshitake Nishimune
Teratocarcinoma F9 cells induced to differentiate with sodium butyrate produce both tissue-type and urokinase-type plasminogen activators.
Journal of cellular biochemistry 1992;49(3):284-9.
1992: Uichi Koshimizu; D Watanabe; Y Tajima; Yoshitake Nishimune
Effects of W (c-kit) gene mutation on gametogenesis in male mice: agametic tubular segments in Wf/Wf testes.
Development (Cambridge, England) 1992;114(4):861-7.
1992: Yuko Nishina; Y Kobarai; T Sumi; M Kosaka; S Nishikawa; Yoshitake Nishimune
Expression of c-kit protooncogene is stimulated by cAMP in differentiated F9 mouse teratocarcinoma cells.
Experimental cell research 1992;198(2):352-6.
1992: Eiichi Morii; S Hirota; H M Kim; K Mikoshiba; Yoshitake Nishimune; Y Kitamura; Shintaro Nomura
Spatial expression of genes encoding c-kit receptors and their ligands in mouse cerebellum as revealed by in situ hybridization.
Brain research. Developmental brain research 1992;65(1):123-6.
1992: M Mizunuma; Kayoko Dohmae; Y Tajima; Uichi Koshimizu; D Watanabe; Yoshitake Nishimune
Loss of sperm in juvenile spermatogonial depletion (jsd) mutant mice is ascribed to a defect of intratubular environment to support germ cell differentiation.
Journal of cellular physiology 1992;150(1):188-93.
1991: Y Tajima; H Onoue; Y Kitamura; Yoshitake Nishimune
Biologically active kit ligand growth factor is produced by mouse Sertoli cells and is defective in SId mutant mice.
Development (Cambridge, England) 1991;113(3):1031-5.
1991: K Sawada; K Sakamaki; Yoshitake Nishimune
Effect of the W mutation, for white belly spot, on testicular germ cell differentiation in mice.
Journal of reproduction and fertility 1991;93(2):287-94.
1991: T Tsujimura; S Hirota; Shintaro Nomura; Y Niwa; M Yamazaki; T Tono; Eiichi Morii; H M Kim; K Kondo; Yoshitake Nishimune
Characterization of Ws mutant allele of rats: a 12-base deletion in tyrosine kinase domain of c-kit gene.
Blood 1991;78(8):1942-6.
1991: Y Niwa; T Kasugai; K Ohno; M Morimoto; M Yamazaki; Kayoko Dohmae; Yoshitake Nishimune; K Kondo; Y Kitamura
Anemia and mast cell depletion in mutant rats that are homozygous at "white spotting (Ws)" locus.
Blood 1991;78(8):1936-41.
1991: Uichi Koshimizu; K Sawada; Y Tajima; D Watanabe; Yoshitake Nishimune
White-spotting mutations affect the regenerative differentiation of testicular germ cells: demonstration by experimental cryptorchidism and its surgical reversal.
Biology of reproduction 1991;45(4):642-8.
1991: Y Tajima; K Sakamaki; D Watanabe; Uichi Koshimizu; T Matsuzawa; Yoshitake Nishimune
Steel-Dickie (Sld) mutation affects both maintenance and differentiation of testicular germ cells in mice.
Journal of reproduction and fertility 1991;91(2):441-9.
1991: M Kosaka; Yuko Nishina; Masatoshi Takeda; K Matsumoto; Yoshitake Nishimune
Reversible effects of sodium butyrate on the differentiation of F9 embryonal carcinoma cells.
Experimental cell research 1991;192(1):46-51.
1989: K Sakamaki; K Sawada; Uichi Koshimizu; Yoshitake Nishimune
Identification of peanut agglutinin receptors on mouse testicular germ cells.
Biology of reproduction 1989;41(6):1097-102.
1989: Yoshitake Nishimune; Yuko Nishina; T Sumi; M Kosaka; Masatoshi Takeda; K Matsumoto; A Matsushiro; Masayoshi Sakuda
Isolation of mutants showing temperature-sensitive cell growth from embryonal carcinoma cells: control of stem cell differentiation by incubation temperatures.
Biochemical and biophysical research communications 1989;165(1):65-72.
1989: Yoshitake Nishimune; M Kosaka; Yuko Nishina; T Sumi; Masayoshi Sakuda; Masatoshi Takeda; K Matsumoto
Inhibition of DNA synthesis causes stem cell differentiation: induction of teratocarcinoma F9 cell differentiation with nucleoside analogues of DNA-synthesis inhibitors and their inducing abilities counterbalanced specifically by normal nucleosides.
Biochemical and biophysical research communications 1989;163(3):1290-7.
1989: Yoshitake Nishimune; K Sawada; Y Tajima; D Watanabe; M Maekawa; K Sakamaki; Akihiko Okuyama; M Nakamura; M Namiki; K Matsumoto
Secretion of plasminogen activator in response to follicle-stimulating hormone in culture medium of human testicular cells from biopsy specimens.
Journal of andrology 1989;10(4):283-8.
1989: H Kuroda; H Nakayama; M Namiki; K Matsumoto; Yoshitake Nishimune; Y Kitamura
Differentiation of germ cells in seminiferous tubules transplanted to testes of germ cell-deficient mice of W/Wv and Sl/Sld genotypes.
Journal of cellular physiology 1989;139(2):329-34.
1989: M Nakamura; Norio Nonomura; M Namiki; Akihiko Okuyama; Eitetsu Koh; N Kondoh; M Takeyama; H Fujioka; H Kiyohara; Yoshitake Nishimune
Impaired DNA synthesis by early pubertal cryptorchid testis in vitro.
Archives of andrology 1989;22(2):137-41.
1989: Akihiko Okuyama; Norio Nonomura; Eitetsu Koh; N Kondoh; M Nakamura; M Namiki; H Kiyohara; H Fujioka; S Mizutani; Yoshitake Nishimune
Plasminogen activator activity of testicular cells of subfertile men and FSH in vitro.
Archives of andrology 1989;23(3):235-42.
1989: Akihiko Okuyama; Norio Nonomura; Eitetsu Koh; N Kondoh; M Nakamura; M Namiki; H Kiyohara; Yoshitake Nishimune; K Matsumoto; M Matsuda
Induction of testicular DNA synthesis in vitro by hCG and hMG treatments in men with hypogonadotropic hypogonadism.
Archives of andrology 1989;23(1):39-43.
1989: Akihiko Okuyama; Norio Nonomura; Eitetsu Koh; N Kondoh; M Nakamura; M Namiki; H Kiyohara; Yoshitake Nishimune; K Matsumoto; T Sonoda
In vitro responsiveness of human testicular DNA synthesis to gonadotropins.
Archives of andrology 1989;22(2):161-5.
1989: Akihiko Okuyama; Norio Nonomura; M Nakamura; M Namiki; Eitetsu Koh; N Kondoh; H Kiyohara; Yoshitake Nishimune; K Matsumoto; T Sonoda
Effectiveness of hMG-hCG treatment for DNA/RNA syntheses in subfertile human testis in vitro.
Archives of andrology 1989;22(2):167-72.
1989: M Nakamura; Norio Nonomura; M Namiki; Akihiko Okuyama; Eitetsu Koh; N Kondoh; H Fujioka; Yoshitake Nishimune; K Matsumoto; M Matsuda
DNA and RNA synthesis by postpubertal undescended testis in vitro.
Archives of andrology 1989;22(1):91-4.
1988: H Nakayama; H Kuroda; H Onoue; J Fujita; Yoshitake Nishimune; K Matsumoto; T Nagano; F Suzuki; Y Kitamura
Studies of Sl/Sld in equilibrium with +/+ mouse aggregation chimaeras. II. Effect of the steel locus on spermatogenesis.
Development (Cambridge, England) 1988;102(1):117-26.
1988: M Nakamura; M Namiki; Akihiko Okuyama; E Koh; N Kondoh; M Takeyama; H Fujioka; Yoshitake Nishimune; K Matsumoto; M Matsuda
Optimal temperature for synthesis of DNA, RNA, and protein by human testis in vitro.
Archives of andrology 1988;20(1):41-4.
1987: M Namiki; Norio Nonomura; M Nakamura; Akihiko Okuyama; T Sonoda; Yoshitake Nishimune; K Matsumoto
Effects of a gonadotropin-releasing hormone agonist analog (ICI 118630) on endocrine functions of human testis in vivo and in vitro.
Fertility and sterility 1987;48(6):1012-7.
1987: K Sakamaki; K Sawada; Yoshitake Nishimune
Identification of the specific proteins associated with differentiation of spermatogonia in mice by two-dimensional gel electrophoresis.
Biology of reproduction 1987;37(4):989-94.
1987: M Namiki; M Nakamura; Akihiko Okuyama; T Sonoda; Hiroaki Itatani; H Sugao; T Sakurai; Yoshitake Nishimune; K Matsumoto
Reduction of human and rat testicular follicle stimulating hormone receptors by human menopausal gonadotrophin in vivo and in vitro.
Clinical endocrinology 1987;26(6):675-84.
1986: Yoshitake Nishimune; K Sakamaki; K Sawada; M Maekawa; T Haneji
Testicular germ cell differentiation.
The Tokai journal of experimental and clinical medicine 1986;11(6):391-4.
1986: Yoshitake Nishimune; M Maekawa; K Sakamaki; T Haneji
Effect of duration of cryptorchidism on ability of mouse germ cells to regenerate and differentiate.
Archives of andrology 1986;16(1):89-96.
1985: Yoshitake Nishimune; T Haneji; M Maekawa; K Sakamaki; Y Kitamura
Effects of steel mutation on spermatogenesis stimulated by fetuin.
Archives of andrology 1985;15(2-3):117-21.