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Makoto Nishiyama
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37
Horinouchi, Sueharu
17
Yamane, Hisakazu
16
Kuzuyama, Tomohisa
12
Kobashi, Nobuyuki
10
Tomita, Takeo
9
Nojiri, Hideaki
7
Tanokura, Masaru
6
Fushinobu, Shinya
6
Omori, Toshio
6
Miyazaki, Junichi
6
Adman, Elinor
5
Komagata, Masashi
5
Shibuya, Naoto
5
Minami, Eiichi
4
Okada, Kazunori
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All Publications
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2009: Ouchi Takuya; Tomita Takeo; Miyagawa Tomoharu; Kuzuyama Tomohisa; Nishiyama Makoto
Dual roles of a conserved pair, Arg23 and Ser20, in recognition of multiple substrates in alpha-aminoadipate aminotransferase from Thermus thermophilus.
Biochemical and biophysical research communications 2009;388(1):21-7.
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2009: Horie Akira; Tomita Takeo; Saiki Asako; Kono Hidetoshi; Taka Hikari; Mineki Reiko; Fujimura Tsutomu; Nishiyama Chiharu; Kuzuyama Tomohisa; Nishiyama Makoto
Discovery of proteinaceous N-modification in lysine biosynthesis of Thermus thermophilus.
Nature chemical biology 2009;5(9):673-9.
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2009: Kim Seung-Young; Zhao Ping; Igarashi Masayuki; Sawa Ryuichi; Tomita Takeo; Nishiyama Makoto; Kuzuyama Tomohisa
Cloning and heterologous expression of the cyclooctatin biosynthetic gene cluster afford a diterpene cyclase and two p450 hydroxylases.
Chemistry & biology 2009;16(7):736-43.
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2009: Ozaki Taro; Mishima Satoshi; Nishiyama Makoto; Kuzuyama Tomohisa
NovQ is a prenyltransferase capable of catalyzing the addition of a dimethylallyl group to both phenylpropanoids and flavonoids.
The Journal of antibiotics 2009;62(7):385-92.
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2009: Yoshida Ayako; Tomita Takeo; Kono Hidetoshi; Fushinobu Shinya; Kuzuyama Tomohisa; Nishiyama Makoto
Crystal structures of the regulatory subunit of Thr-sensitive aspartate kinase from Thermus thermophilus.
The FEBS journal 2009;276(11):3124-36.
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2009: Tomita Takeo; Miyagawa Tomoharu; Miyazaki Takashi; Fushinobu Shinya; Kuzuyama Tomohisa; Nishiyama Makoto
Mechanism for multiple-substrates recognition of alpha-aminoadipate aminotransferase from Thermus thermophilus.
Proteins 2009;75(2):348-59.
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2009: Zhao Ping; Ueda Jun-ya; Kozone Ikuko; Chijiwa Shuhei; Takagi Motoki; Kudo Fumitaka; Nishiyama Makoto; Shin-ya Kazuo; Kuzuyama Tomohisa
New glycosylated derivatives of versipelostatin, the GRP78/Bip molecular chaperone down-regulator, from Streptomyces versipellis 4083-SVS6.
Organic & biomolecular chemistry 2009;7(7):1454-60.
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2008: Kumano Takuto; Richard Stéphane B; Noel Joseph P; Nishiyama Makoto; Kuzuyama Tomohisa
Chemoenzymatic syntheses of prenylated aromatic small molecules using Streptomyces prenyltransferases with relaxed substrate specificities.
Bioorganic & medicinal chemistry 2008;16(17):8117-26.
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2007: Sobajima Hiroyuki; Tani Tomoyuki; Chujo Tetsuya; Okada Kazunori; Suzuki Kazuya; Mori Satoshi; Minami Eiichi; Nishiyama Makoto; Nojiri Hideaki; Yamane Hisakazu
Identification of a jasmonic acid-responsive region in the promoter of the rice 12-oxophytodienoic acid reductase 1 gene OsOPR1.
Bioscience, biotechnology, and biochemistry 2007;71(12):3110-5.
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2007: Komagata Masashi; Inahata Yuji; Nishiyama Makoto; Endo Kenji; Tanaka Hidetoshi; Kobayashi Hiroto
Treatment of myelopathy due to cervicothoracic OPLL via open door laminoplasty.
Journal of spinal disorders & techniques 2007;20(5):342-6.
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2007: Yoshida Ayako; Tomita Takeo; Kurihara Takeshi; Fushinobu Shinya; Kuzuyama Tomohisa; Nishiyama Makoto
Structural Insight into concerted inhibition of alpha 2 beta 2-type aspartate kinase from Corynebacterium glutamicum.
Journal of molecular biology 2007;368(2):521-36.
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2007: Yoshida Ayako; Tomita Takeo; Kuzuyama Tomohisa; Nishiyama Makoto
Purification, crystallization and preliminary X-ray analysis of the regulatory subunit of aspartate kinase from Thermus thermophilus.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 2):96-8.
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2006: Fujiwara Kei; Tsubouchi Taishi; Kuzuyama Tomohisa; Nishiyama Makoto
Involvement of the arginine repressor in lysine biosynthesis of Thermus thermophilus.
Microbiology (Reading, England) 2006;152(Pt 12):3585-94.
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2006: Tomita Takeo; Kuzuyama Tomohisa; Nishiyama Makoto
Alteration of coenzyme specificity of lactate dehydrogenase from Thermus thermophilus by introducing the loop region of NADP(H)-dependent malate dehydrogenase.
Bioscience, biotechnology, and biochemistry 2006;70(9):2230-5.
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2006: Tomita Takeo; Fushinobu Shinya; Kuzuyama Tomohisa; Nishiyama Makoto
Structural basis for the alteration of coenzyme specificity in a malate dehydrogenase mutant.
Biochemical and biophysical research communications 2006;347(2):502-8.
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2005: Miyazaki Junichi; Asada Kuniko; Fushinobu Shinya; Kuzuyama Tomohisa; Nishiyama Makoto
Crystal structure of tetrameric homoisocitrate dehydrogenase from an extreme thermophile, Thermus thermophilus: involvement of hydrophobic dimer-dimer interaction in extremely high thermotolerance.
Journal of bacteriology 2005;187(19):6779-88.
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2005: Tomita Takeo; Fushinobu Shinya; Kuzuyama Tomohisa; Nishiyama Makoto
Crystal structure of NAD-dependent malate dehydrogenase complexed with NADP(H).
Biochemical and biophysical research communications 2005;334(2):613-8.
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2005: Tsubouchi Taishi; Mineki Reiko; Taka Hikari; Kaga Naoko; Murayama Kimie; Nishiyama Chiharu; Yamane Hisakazu; Kuzuyama Tomohisa; Nishiyama Makoto
Leader peptide-mediated transcriptional attenuation of lysine biosynthetic gene cluster in Thermus thermophilus.
The Journal of biological chemistry 2005;280(18):18511-6.
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2004: Kiribuchi Kyoko; Sugimori Miho; Takeda Masayoshi; Otani Takashi; Okada Kazunori; Onodera Haruko; Ugaki Masashi; Tanaka Yuji; Tomiyama-Akimoto Chiharu; Yamaguchi Takeshi; Minami Eiichi; Shibuya Naoto; Omori Toshio; Nishiyama Makoto; Nojiri Hideaki; Yamane Hisakazu
RERJ1, a jasmonic acid-responsive gene from rice, encodes a basic helix-loop-helix protein.
Biochemical and biophysical research communications 2004;325(3):857-63.
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2004: Komagata Masashi; Nishiyama Makoto; Endo Kenji; Ikegami Hitoshi; Tanaka Satoshi; Imakiire Atsuhiro
Prophylaxis of C5 palsy after cervical expansive laminoplasty by bilateral partial foraminotomy.
The spine journal : official journal of the North American Spine Society 2004;4(6):650-5.
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2004: Nemoto Tadahiro; Cho Eun-Min; Okada Atsushi; Okada Kazunori; Otomo Kazuko; Kanno Yuri; Toyomasu Tomonobu; Mitsuhashi Wataru; Sassa Takeshi; Minami Eiichi; Shibuya Naoto; Nishiyama Makoto; Nojiri Hideaki; Yamane Hisakazu
Stemar-13-ene synthase, a diterpene cyclase involved in the biosynthesis of the phytoalexin oryzalexin S in rice.
FEBS letters 2004;571(1-3):182-6.
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2004: Jikumaru Yusuke; Asami Tadao; Seto Hideharu; Yoshida Shigeo; Yokoyama Tadashi; Obara Naomi; Hasegawa Morifumi; Kodama Osamu; Nishiyama Makoto; Okada Kazunori; Nojiri Hideaki; Yamane Hisakazu
Preparation and biological activity of molecular probes to identify and analyze jasmonic acid-binding proteins.
Bioscience, biotechnology, and biochemistry 2004;68(7):1461-6.
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2004: Miyazaki Takashi; Miyazaki Junichi; Yamane Hisakazu; Nishiyama Makoto
alpha-Aminoadipate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus.
Microbiology (Reading, England) 2004;150(Pt 7):2327-34.
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2004: Komagata Masashi; Nishiyama Makoto; Imakiire Atshuhiro; Kato Hirobumi
Total spondylectomy for en bloc resection of lung cancer invading the chest wall and thoracic spine. Case report.
Journal of neurosurgery 2004;100(4 Suppl Spine):353-7.
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2004: Kato Chiaki; Kurihara Takeshi; Kobashi Nobuyuki; Yamane Hisakazu; Nishiyama Makoto
Conversion of feedback regulation in aspartate kinase by domain exchange.
Biochemical and biophysical research communications 2004;316(3):802-8.
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2004: Komagata M; Endo K; Nishiyama M; Ikegami H; Imakiire A
Management of tight filum terminale.
Minimally invasive neurosurgery : MIN 2004;47(1):49-53.
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2004: Cho Eun-Min; Okada Atsushi; Kenmoku Hiromichi; Otomo Kazuko; Toyomasu Tomonobu; Mitsuhashi Wataru; Sassa Takeshi; Yajima Arata; Yabuta Goro; Mori Kenji; Oikawa Hideaki; Toshima Hiroaki; Shibuya Naoto; Nojiri Hideaki; Omori Toshio; Nishiyama Makoto; Yamane Hisakazu
Molecular cloning and characterization of a cDNA encoding ent-cassa-12,15-diene synthase, a putative diterpenoid phytoalexin biosynthetic enzyme, from suspension-cultured rice cells treated with a chitin elicitor.
The Plant journal : for cell and molecular biology 2004;37(1):1-8.
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2003: Sobajima Hiroyuki; Takeda Masayoshi; Sugimori Miho; Kobashi Nobuyuki; Kiribuchi Kyoko; Cho Eun-Min; Akimoto Chiharu; Yamaguchi Takeshi; Minami Eiichi; Shibuya Naoto; Schaller Florian; Weiler Elmar W; Yoshihara Teruhiko; Nishida Hiromi; Nojiri Hideaki; Omori Toshio; Nishiyama Makoto; Yamane Hisakazu
Cloning and characterization of a jasmonic acid-responsive gene encoding 12-oxophytodienoic acid reductase in suspension-cultured rice cells.
Planta 2003;216(4):692-8.
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2003: Miyazaki Junichi; Kobashi Nobuyuki; Nishiyama Makoto; Yamane Hisakazu
Characterization of homoisocitrate dehydrogenase involved in lysine biosynthesis of an extremely thermophilic bacterium, Thermus thermophilus HB27, and evolutionary implication of beta-decarboxylating dehydrogenase.
The Journal of biological chemistry 2003;278(3):1864-71.
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2003: Endo Kenji; Komagata Masashi; Ikegami Hitoshi; Nishiyama Makoto; Tanaka Satoshi; Imakiire Atsuhiro; Serizawa Hiromi
Dumbbell-type solitary fibrous tumor in the cervical spine.
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 2003;8(3):428-31.
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2002: Furumai Ryohei; Matsuyama Akihisa; Kobashi Nobuyuki; Lee Kun-Hyung; Nishiyama Makoto; Nakajima Hidenori; Tanaka Akito; Komatsu Yasuhiko; Nishino Norikazu; Yoshida Minoru; Horinouchi Sueharu
FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases.
Cancer research 2002;62(17):4916-21.
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2002: Wulandari Asri Peni; Miyazaki Junichi; Kobashi Nobuyuki; Nishiyama Makoto; Hoshino Takayuki; Yamane Hisakazu
Characterization of bacterial homocitrate synthase involved in lysine biosynthesis.
FEBS letters 2002;522(1-3):35-40.
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2002: Sugimori Miho; Kiribuchi Kyoko; Akimoto Chiharu; Yamaguchi Takeshi; Minami Eiichi; Shibuya Naoto; Sobajima Hiroyuki; Cho Eun-Min; Kobashi Nobuyuki; Nojiri Hideaki; Omori Toshio; Nishiyama Makoto; Yamane Hisakazu
Cloning and characterization of cDNAs for the jasmonic acid-responsive Genes RRJ1 and RRJ2 in suspension-cultured rice cells.
Bioscience, biotechnology, and biochemistry 2002;66(5):1140-2.
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2002: Okuno Atsuro; Hasegawa Yuriko; Nishiyama Makoto; Ohira Tsuyoshi; Ko Rinkei; Kurihara Masaaki; Matsumoto Shogo; Nagasawa Hiromichi
Preparation of an active recombinant peptide of crustacean androgenic gland hormone.
Peptides 2002;23(3):567-72.
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2002: Miyazaki Junichi; Kobashi Nobuyuki; Fujii Tomoyuki; Nishiyama Makoto; Yamane Hisakazu
Characterization of a lysK gene as an argE homolog in Thermus thermophilus HB27.
FEBS letters 2002;512(1-3):269-74.
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2001: Kurumatani M; Yagi K; Murata T; Tezuka M; Mander L N; Nishiyama M; Yama H
Isolation and identification of antheridiogens in the ferns, Lygodium microphyllum and Lygodium reticulatum.
Bioscience, biotechnology, and biochemistry 2001;65(10):2311-4.
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2001: Miyazaki J; Kobashi N; Nishiyama M; Yamane H
Functional and evolutionary relationship between arginine biosynthesis and prokaryotic lysine biosynthesis through alpha-aminoadipate.
Journal of bacteriology 2001;183(17):5067-73.
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2001: Yoshida M; Furumai R; Nishiyama M; Komatsu Y; Nishino N; Horinouchi S
Histone deacetylase as a new target for cancer chemotherapy.
Cancer chemotherapy and pharmacology 2001;48 Suppl 1():S20-6.
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2001: Kobashi N; Nishiyama M; Yamane H
Characterization of aspartate kinase III of Bacillus subtilis.
Bioscience, biotechnology, and biochemistry 2001;65(6):1391-4.
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2001: Yagi K; Chujo T; Nojiri H; Omori T; Nishiyama M; Yamane H
Evidence for the presence of DNA-binding proteins involved in regulation of the gene expression of indole-3-pyruvic acid decarboxylase, a key enzyme in indole-3-acetic acid biosynthesis in Azospirillum lipoferum FS.
Bioscience, biotechnology, and biochemistry 2001;65(5):1265-9.
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2000: Yagi K; Matsumoto T; Chujo T; Nojiri H; Omori T; Minamisawa K; Nishiyama M; Yamane H
Isolation and characterization of low-indole-3-acetic acid-producing mutants from Bradyrhizobium elkanii.
Bioscience, biotechnology, and biochemistry 2000;64(7):1359-64.
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2000: Kukimoto M; Nishiyama M; Tanokura M; Horinouchi S
Gene organization for nitric oxide reduction in Alcaligenes faecalis S-6.
Bioscience, biotechnology, and biochemistry 2000;64(4):852-7.
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1999: Kudo H; Natsume R; Nishiyama M; Horinouchi S
Analysis of stability and catalytic properties of two tryptophanases from a thermophile.
Protein engineering 1999;12(8):687-92.
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1999: Nishiyama M; Kobashi N; Tanaka K; Takahashi H; Tanokura M
Cloning and characterization in Escherichia coli of the gene encoding the principal sigma factor of an extreme thermophile, Thermus thermophilus.
FEMS microbiology letters 1999;172(2):179-86.
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1999: Kobashi N; Nishiyama M; Tanokura M
Aspartate kinase-independent lysine synthesis in an extremely thermophilic bacterium, Thermus thermophilus: lysine is synthesized via alpha-aminoadipic acid not via diaminopimelic acid.
Journal of bacteriology 1999;181(6):1713-8.
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1999: Kobashi N; Nishiyama M; Tanokura M
Kinetic and mutation analyses of aspartate kinase from Thermus flavus.
Journal of bioscience and bioengineering 1999;87(6):739-45.
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1998: Mizunashi W; Nishiyama M; Horinouchi S; Beppu T
Overexpression of high-molecular-mass nitrile hydratase from Rhodococcus rhodochrous J1 in recombinant Rhodococcus cells.
Applied microbiology and biotechnology 1998;49(5):568-72.
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1998: Kono H; Nishiyama M; Tanokura M; Doi J
Designing the hydrophobic core of Thermus flavus malate dehydrogenase based on side-chain packing.
Protein engineering 1998;11(1):47-52.
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1998: Sasaki S; Karube I; Hirota N; Arikawa Y; Nishiyama M; Kukimoto M; Horinouchi S; Beppu T
Application of nitrite reductase from Alcaligenes faecalis S-6 for nitrite measurement.
Biosensors & bioelectronics 1998;13(1):1-5.
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1997: Kono H; Nishiyama M; Tanokura M; Doi J
Design of hydrophobic core of E. coli malate dehydrogenase based on the side-chain packing.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 1997;():210-21.
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1996: Park Y N; Aikawa J; Nishiyama M; Horinouchi S; Beppu T
Involvement of a residue at position 75 in the catalytic mechanism of a fungal aspartic proteinase, Rhizomucor pusillus pepsin. Replacement of tyrosine 75 on the flap by asparagine enhances catalytic efficiency.
Protein engineering 1996;9(10):869-75.
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1996: Kukimoto M; Nishiyama M; Tanokura M; Murphy M E; Adman E T; Horinouchi S
Site-directed mutagenesis of azurin from Pseudomonas aeruginosa enhances the formation of an electron-transfer complex with a copper-containing nitrite reductase from Alcaligenes faecalis S-6.
FEBS letters 1996;394(1):87-90.
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1996: Nishiyama M; Kinoshita M; Kudo H; Horinouchi S; Tanokura M
Enhancement of the turnover number of thermostable malate dehydrogenase by deleting hydrogen bonds around the catalytic site.
Biochemical and biophysical research communications 1996;225(3):844-8.
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1996: Kukimoto M; Nishiyama M; Tanokura M; Adman E T; Horinouchi S
Studies on protein-protein interaction between copper-containing nitrite reductase and pseudoazurin from Alcaligenes faecalis S-6.
The Journal of biological chemistry 1996;271(23):13680-3.
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1995: Murphy M E; Turley S; Kukimoto M; Nishiyama M; Horinouchi S; Sasaki H; Tanokura M; Adman E T
Structure of Alcaligenes faecalis nitrite reductase and a copper site mutant, M150E, that contains zinc.
Biochemistry 1995;34(38):12107-17.
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1995: Nishiyama M; Kukimoto M; Beppu T; Horinouchi S
An operon encoding aspartokinase and purine phosphoribosyltransferase in Thermus flavus.
Microbiology (Reading, England) 1995;141 ( Pt 5)():1211-9.
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1995: Kukimoto M; Nishiyama M; Ohnuki T; Turley S; Adman E T; Horinouchi S; Beppu T
Identification of interaction site of pseudoazurin with its redox partner, copper-containing nitrite reductase from Alcaligenes faecalis S-6.
Protein engineering 1995;8(2):153-8.
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1995: Park Y N; Nishiyama M; Horinouchi S; Beppu T
Site-directed mutagenesis revealed role of subsite residues of Mucor pusillus pepsin in catalytic function.
Advances in experimental medicine and biology 1995;362():559-63.
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1995: Beppu T; Park Y N; Aikawa J; Nishiyama M; Horinouchi S
Tyrosine 75 on the flap contributes to enhance catalytic efficiency of a fungal aspartic proteinase, Mucor pusillus pepsin.
Advances in experimental medicine and biology 1995;362():501-9.
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1994: Ohnishi Y; Nishiyama M; Horinouchi S; Beppu T
Involvement of the COOH-terminal pro-sequence of Serratia marcescens serine protease in the folding of the mature enzyme.
The Journal of biological chemistry 1994;269(52):32800-6.
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1994: Hashimoto Y; Nishiyama M; Horinouchi S; Beppu T
Nitrile hydratase gene from Rhodococcus sp. N-774 requirement for its downstream region for efficient expression.
Bioscience, biotechnology, and biochemistry 1994;58(10):1859-65.
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1994: Hitomi J; Park J S; Nishiyama M; Horinouchi S; Beppu T
Substrate-dependent change in the pH-activity profile of alkaline endo-1,4-beta-glucanase from an alkaline Bacillus sp.
Journal of biochemistry 1994;116(3):554-9.
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1994: Kukimoto M; Nishiyama M; Murphy M E; Turley S; Adman E T; Horinouchi S; Beppu T
X-ray structure and site-directed mutagenesis of a nitrite reductase from Alcaligenes faecalis S-6: roles of two copper atoms in nitrite reduction.
Biochemistry 1994;33(17):5246-52.
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1994: Nishiyama M; Beppu T
[Preparation of mutant enzymes by means of refolding of polypeptide forming inclusion bodies and secretory expression system]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1994;39(7):1366-72.
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1993: Kobayashi M; Komeda H; Nagasawa T; Nishiyama M; Horinouchi S; Beppu T; Yamada H; Shimizu S
Amidase coupled with low-molecular-mass nitrile hydratase from Rhodococcus rhodochrous J1. Sequencing and expression of the gene and purification and characterization of the gene product.
European journal of biochemistry / FEBS 1993;217(1):327-36.
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1993: Duran R; Nishiyama M; Horinouchi S; Beppu T
Characterization of nitrile hydratase genes cloned by DNA screening from Rhodococcus erythropolis.
Bioscience, biotechnology, and biochemistry 1993;57(8):1323-8.
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1993: Nishiyama M; Suzuki J; Kukimoto M; Ohnuki T; Horinouchi S; Beppu T
Cloning and characterization of a nitrite reductase gene from Alcaligenes faecalis and its expression in Escherichia coli.
Journal of general microbiology 1993;139(4):725-33.
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1993: Nishiyama M; Birktoft J J; Beppu T
Alteration of coenzyme specificity of malate dehydrogenase from Thermus flavus by site-directed mutagenesis.
The Journal of biological chemistry 1993;268(7):4656-60.
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1993: Yonezawa M; Suzuki J; Nishiyama M; Horinouchi S; Beppu T
Role of the amino-terminal amino acid sequences determining the in vitro refolding process of prochymosin polypeptide.
Journal of biotechnology 1993;28(1):85-97.
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1992: Hashimoto Y; Nishiyama M; Yu F; Watanabe I; Horinouchi S; Beppu T
Development of a host-vector system in a Rhodococcus strain and its use for expression of the cloned nitrile hydratase gene cluster.
Journal of general microbiology 1992;138(5):1003-10.
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1992: Nishiyama M; Suzuki J; Ohnuki T; Chang H C; Horinouchi S; Turley S; Adman E T; Beppu T
Site-directed mutagenesis of pseudoazurin from Alcaligenes faecalis S-6; Pro80Ala mutant exhibits marked increase in reduction potential.
Protein engineering 1992;5(2):177-84.
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1992: Aikawa J; Nishiyama M; Beppu T
Protein engineering of the milk-clotting aspartic proteinases.
Scandinavian journal of clinical and laboratory investigation. Supplementum 1992;210():51-8.
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1991: Kobayashi M; Nishiyama M; Nagasawa T; Horinouchi S; Beppu T; Yamada H
Cloning, nucleotide sequence and expression in Escherichia coli of two cobalt-containing nitrile hydratase genes from Rhodococcus rhodochrous J1.
Biochimica et biophysica acta 1991;1129(1):23-33.
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1991: Nishiyama M; Shimada K; Horinouchi S; Beppu T
Role of threonine 190 in modulating the catalytic function of malate dehydrogenase from a thermophile Thermus flavus.
The Journal of biological chemistry 1991;266(22):14294-9.
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1991: Nishiyama M; Horinouchi S; Beppu T
Characterization of an operon encoding succinyl-CoA synthetase and malate dehydrogenase from Thermus flavus AT-62 and its expression in Escherichia coli.
Molecular & general genetics : MGG 1991;226(1-2):1-9.
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1991: Nishiyama M; Horinouchi S; Kobayashi M; Nagasawa T; Yamada H; Beppu T
Cloning and characterization of genes responsible for metabolism of nitrile compounds from Pseudomonas chlororaphis B23.
Journal of bacteriology 1991;173(8):2465-72.
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1991: Hashimoto Y; Nishiyama M; Ikehata O; Horinouchi S; Beppu T
Cloning and characterization of an amidase gene from Rhodococcus species N-774 and its expression in Escherichia coli.
Biochimica et biophysica acta 1991;1088(2):225-33.
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1991: Aikawa J; Hiramatsu R; Nishiyama M; Horinouchi S; Beppu T
A yeast expression system and site-directed mutagenesis of a fungal aspartic proteinase, Mucor rennin.
Advances in experimental medicine and biology 1991;306():233-42.
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1990: Suzuki J; Hamu A; Nishiyama M; Horinouchi S; Beppu T
Site-directed mutagenesis reveals functional contribution of Thr218, Lys220 and Asp304 in chymosin.
Protein engineering 1990;4(1):69-71.
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1990: Aikawa J; Yamashita T; Nishiyama M; Horinouchi S; Beppu T
Effects of glycosylation on the secretion and enzyme activity of Mucor rennin, an aspartic proteinase of Mucor pusillus, produced by recombinant yeast.
The Journal of biological chemistry 1990;265(23):13955-9.
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1989: Ikehata O; Nishiyama M; Horinouchi S; Beppu T
Primary structure of nitrile hydratase deduced from the nucleotide sequence of a Rhodococcus species and its expression in Escherichia coli.
European journal of biochemistry / FEBS 1989;181(3):563-70.
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1989: Suzuki J; Sasaki K; Sasao Y; Hamu A; Kawasaki H; Nishiyama M; Horinouchi S; Beppu T
Alteration of catalytic properties of chymosin by site-directed mutagenesis.
Protein engineering 1989;2(7):563-9.
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1989: Horinouchi S; Suzuki H; Nishiyama M; Beppu T
Nucleotide sequence and transcriptional analysis of the Streptomyces griseus gene (afsA) responsible for A-factor biosynthesis.
Journal of bacteriology 1989;171(2):1206-10.
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1987: Horinouchi S; Nishiyama M; Nakamura A; Beppu T
Construction and characterization of multicopy expression-vectors in Streptomyces spp.
Molecular & general genetics : MGG 1987;210(3):468-75.
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