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Leo Niskanen

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Riitta Törrönen; Marjukka Kolehmainen; Hannu M Mykkänen; Kaisa S Poutanen; Essi Sarkkinen; Leo Niskanen
Berries reduce postprandial insulin responses to wheat and rye breads in healthy women.
Eeva Korpi-Hyövälti; David E Laaksonen; Seppo Heinonen; Ursula Schwab; Leo Niskanen
Effect of intensive counselling on physical activity in pregnant women at high risk for gestational diabetes mellitus. A clinical study in primary care.
Nina Rautio; Timo Saaristo; Juha Saltevo; Jaakko Tuomilehto; Matti Uusitupa; Eeva Korpi-Hyövälti; Leo Niskanen; Heikki Oksa; Markku Peltonen; Jari Jokelainen; Sirkka Keinänen-Kiukaanniemi
Participation, socioeconomic status and group or individual counselling intervention in individuals at high risk for type 2 diabetes: one-year follow-up study of the FIN-D2D-project.

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All Publications

2013: Riitta Törrönen; Marjukka Kolehmainen; Hannu M Mykkänen; Kaisa S Poutanen; Essi Sarkkinen; Leo Niskanen
Berries reduce postprandial insulin responses to wheat and rye breads in healthy women.
The Journal of nutrition 2013;143(4):430-6.
2012: Eeva Korpi-Hyövälti; David E Laaksonen; Seppo Heinonen; Ursula Schwab; Leo Niskanen
Effect of intensive counselling on physical activity in pregnant women at high risk for gestational diabetes mellitus. A clinical study in primary care.
Primary care diabetes 2012;6(4):261-8.
2012: Nina Rautio; Timo Saaristo; Juha Saltevo; Jaakko Tuomilehto; Matti Uusitupa; Eeva Korpi-Hyövälti; Leo Niskanen; Heikki Oksa; Markku Peltonen; Jari Jokelainen; Sirkka Keinänen-Kiukaanniemi
Participation, socioeconomic status and group or individual counselling intervention in individuals at high risk for type 2 diabetes: one-year follow-up study of the FIN-D2D-project.
Primary care diabetes 2012;6(4):277-83.
2012: Riitta Törrönen; Essi Sarkkinen; Marjukka Kolehmainen; Hannu M Mykkänen; Leo Niskanen
Postprandial glucose, insulin, and free fatty acid responses to sucrose consumed with blackcurrants and lingonberries in healthy women.
The American journal of clinical nutrition 2012;96(3):527-33.
2012: Eeva Korpi-Hyövälti; David E Laaksonen; Hilpi Linjama; Seppo Heinonen; Ursula Schwab; Leo Niskanen
Effect of intensive counselling on the quality of dietary fats in pregnant women at high risk of gestational diabetes mellitus.
The British journal of nutrition 2012;108(5):910-7.
2012: Seppo Lehto; Leo Niskanen; Heli Ruotsalainen; Sanna Sinikallio; Tommi Tolmunen; Minna Valkonen-Korhonen; Heimo Viinamäki; Antti-Pekka Elomaa; Karl-Heinz Herzig; Kirsi Honkalampi; Anne Huotari; Heli Koivumaa-Honkanen; Jukka Hintikka
Serum adipokine levels in adults with a history of childhood maltreatment.
Progress in neuro-psychopharmacology & biological psychiatry 2012;37(2):217-21.
2012: Sanna M Salmela; Kati Vähäsarja; Mauno Vanhala; Jari Villberg; Sirkka Keinänen-Kiukaanniemi; Eeva Korpi-Hyövälti; Jaana Lindström; Leo Niskanen; Heikki Oksa; Timo Saaristo; Marita Poskiparta
The reporting of previous lifestyle counseling by persons at high risk of Type 2 diabetes.
Patient education and counseling 2012;87(2):178-85.
2012: Riitta Törrönen; Kyllikki Kilpi; Tarja Niskanen; Essi Sarkkinen; Niina Tapola; Leo Niskanen
Postprandial glucose, insulin and glucagon-like peptide 1 responses to sucrose ingested with berries in healthy subjects.
The British journal of nutrition 2012;107(10):1445-51.
2012: J Saarelainen; Marjo Tuppurainen; Jukka Jurvelin; Vesa Kiviniemi; Heikki Kröger; Leo Niskanen; Risto Honkanen
Body mass index and bone loss among postmenopausal women: the 10-year follow-up of the OSTPRE cohort.
Journal of bone and mineral metabolism 2012;30(2):208-16.
2012: Kati Vähäsarja; Mauno Vanhala; Jari Villberg; Pauli Rintala; Timo Saaristo; Sanna Salmela; Sirkka Keinänen-Kiukaanniemi; Eeva Korpi-Hyövälti; Urho M Kujala; Leena Moilanen; Leo Niskanen; Heikki Oksa; Markku Peltonen; Marita Poskiparta
Perceived need to increase physical activity levels among adults at high risk of type 2 diabetes: a cross-sectional analysis within a community-based diabetes prevention project FIN-D2D.
BMC public health 2012;12():514.
2012: Eeva Korpi-Hyövälti; David E Laaksonen; Seppo Heinonen; Ursula Schwab; Leo Niskanen
How can we increase postpartum glucose screening in women at high risk for gestational diabetes mellitus?
International journal of endocrinology 2012;2012():519267.
2012: Antti-Pekka Elomaa; Ilkka T Harvima; Karl-Heinz Herzig; Jukka Hintikka; Kirsi Honkalampi; Heli Koivumaa-Honkanen; Leo Niskanen; Minna Valkonen-Korhonen; Heimo Viinamäki; Soili M Lehto
Elevated levels of serum IL-5 are associated with an increased likelihood of major depressive disorder.
BMC psychiatry 2012;12():2.
2011: Katja Wikström; Sirkka Keinänen-Kiukaanniemi; Eeva Korpi-Hyövälti; Jaana Lindström; Leo Niskanen; Heikki Oksa; Timo E Saaristo; Jaakko Tuomilehto; Matti Uusitupa; Mauno Vanhala; Markku Peltonen
Socio-economic differences in dysglycemia and lifestyle-related risk factors in the Finnish middle-aged population.
European journal of public health 2011;21(6):768-74.
2011: Juha Saltevo; Jouko Sundvall; Jorma Teittinen; Hannu Kautiainen; Eeva Korpi-Hyövälti; Satu Männistö; Pekka Mäntyselkä; Leo Niskanen; Heikki Oksa; Markku Peltonen; Mauno Vanhala
Serum calcium level is associated with metabolic syndrome in the general population: FIN-D2D study.
European journal of endocrinology / European Federation of Endocrine Societies 2011;165(3):429-34.
2011: J T Saltevo; J Sundvall; J Tuomilehto; M Uusitupa; H Kautiainen; S Keinänen-Kiukaanniemi; Pekka Mäntyselkä; Leo Niskanen; H Oksa; M Peltonen; Hannu Puolijoki; M J Vanhala
Ageing and associations of fasting plasma glucose and 2 h plasma glucose with HbA(1C) in apparently healthy population. "FIN-D2D" study.
Diabetes research and clinical practice 2011;93(3):344-9.
2011: J Saarelainen; Risto Honkanen; Heikki Kröger; Marjo Tuppurainen; Jukka S Jurvelin; Leo Niskanen
Body fat distribution is associated with lumbar spine bone density independently of body weight in postmenopausal women.
Maturitas 2011;69(1):86-90.
2011: Pia Pajunen; Sirkka Keinänen-Kiukaanniemi; Eeva Korpi-Hyövälti; Anna Kotronen; Leo Niskanen; Heikki Oksa; Timo Saaristo; Juha T Saltevo; Jouko Sundvall; Matti Uusitupa; Mauno Vanhala; Markku Peltonen
Metabolically healthy and unhealthy obesity phenotypes in the general population: the FIN-D2D Survey.
BMC public health 2011;11():754.
2010: Soili M Lehto; Leo Niskanen; Juhani Miettola; Tommi Tolmunen; Heimo Viinamäki; Pekka Mäntyselkä
Serum anti-inflammatory markers in general population subjects with elevated depressive symptoms.
Neuroscience letters 2010;484(3):201-5.
2010: Seppo Lehto; Anne Huotari; Leo Niskanen; Karl-Heinz Herzig; Tommi Tolmunen; Heimo Viinamäki; Heli Koivumaa-Honkanen; Kirsi Honkalampi; Sanna Sinikallio; Heli Ruotsalainen; Jukka Hintikka
Serum IL-7 and G-CSF in major depressive disorder.
Progress in neuro-psychopharmacology & biological psychiatry 2010;34(6):846-51.
2010: Kirsi Honkalampi; Soili M Lehto; Jukka Hintikka; Heli Koivumaa-Honkanen; Leo Niskanen; Heimo Viinamäki
Symptoms of depression and alexithymic burden in middle-aged men.
Psychotherapy and psychosomatics 2010;79(4):259-61.
2010: Soili M Lehto; Anu Ruusunen; Leo Niskanen; Tommi Tolmunen; Sari Voutilainen; Heimo Viinamäki; George Kaplan; Jussi Kauhanen
Elevated depressive symptoms and compositional changes in LDL particles in middle-aged men.
European journal of epidemiology 2010;25(6):403-9.
2010: T Saharinen; Jukka Hintikka; Leo Niskanen; Jari Kylmä; Heli Koivumaa-Honkanen; Kirsi Honkalampi; Merja Nikkonen; Kaisa Haatainen; Heimo Viinamäki
Health-related quality of life among subjects with long-term mental symptoms in a population-based sample.
Journal of psychiatric and mental health nursing 2010;17(3):260-7.
2010: Seppo Lehto; A Huotari; Leo Niskanen; Tommi Tolmunen; Heli Koivumaa-Honkanen; Kirsi Honkalampi; H Ruotsalainen; K-H Herzig; Heimo Viinamäki; Jukka Hintikka
Serum adiponectin and resistin levels in major depressive disorder.
Acta psychiatrica Scandinavica 2010;121(3):209-15.
2010: Soili M Lehto; Leo Niskanen; Karl-Heinz Herzig; Tommi Tolmunen; Anne Huotari; Heimo Viinamäki; Heli Koivumaa-Honkanen; Kirsi Honkalampi; Heli Ruotsalainen; Jukka Hintikka
Serum chemokine levels in major depressive disorder.
Psychoneuroendocrinology 2010;35(2):226-32.
2010: Anne Huotari; Soili M Lehto; Leo Niskanen; Karl-Heinz Herzig; Jukka Hintikka; Heli Koivumaa-Honkanen; Tommi Tolmunen; Kirsi Honkalampi; Noora Kaikkonen; Heimo Viinamäki
Increased Serum PAI-1 Levels in Subjects with Metabolic Syndrome and Long-Term Adverse Mental Symptoms: A Population-Based Study.
Cardiovascular psychiatry and neurology 2010;2010():501349.
2009: M V Heinonen; David E Laaksonen; T Karhu; Leila J Karhunen; Tomi Laitinen; Sakari Kainulainen; Aila Rissanen; Leo Niskanen; Karl-Heinz Herzig
Effect of diet-induced weight loss on plasma apelin and cytokine levels in individuals with the metabolic syndrome.
Nutrition, metabolism, and cardiovascular diseases : NMCD 2009;19(9):626-33.
2009: Jari Tiihonen; Jouko Lönnqvist; Kristian Wahlbeck; Timo Klaukka; Leo Niskanen; Antti Tanskanen; Jari Haukka
11-year follow-up of mortality in patients with schizophrenia: a population-based cohort study (FIN11 study).
Lancet 2009;374(9690):620-7.
2009: Jukka Hintikka; Leo Niskanen; Heli Koivumaa-Honkanen; Tommi Tolmunen; Kirsi Honkalampi; Soili M Lehto; Heimo Viinamäki
Hypogonadism, decreased sexual desire, and long-term depression in middle-aged men.
The journal of sexual medicine 2009;6(7):2049-57.
2009: Heimo Viinamäki; T Heiskanen; Seppo Lehto; Leo Niskanen; Heli Koivumaa-Honkanen; Tommi Tolmunen; Kirsi Honkalampi; T Saharinen; Kaisa Haatainen; Jukka Hintikka
Association of depressive symptoms and metabolic syndrome in men.
Acta psychiatrica Scandinavica 2009;120(1):23-9.
2009: Pekka Mäntyselkä; Juhani Miettola; Leo Niskanen; Esko Kumpusalo
Persistent pain at multiple sites--connection to glucose derangement.
Diabetes research and clinical practice 2009;84(2):e30-2.
2009: V Kalesnykiene; Iiris Sorri; Raimo Voutilainen; Matti Uusitupa; Leo Niskanen; Hannu Uusitalo
The effect of glycaemic control on the quantitative characteristics of retinopathy lesions in patients with type 2 diabetes mellitus: 10-year follow-up study.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2009;247(3):335-41.
2009: Jukka Hintikka; Soili M Lehto; Leo Niskanen; Anne Huotari; Karl-Heinz Herzig; Heli Koivumaa-Honkanen; Kirsi Honkalampi; Sanna Sinikallio; Heimo Viinamäki
Unemployment and ill health: a connection through inflammation?
BMC public health 2009;9():410.
2009: Maarit Valtonen; David E Laaksonen; Jari Laukkanen; Tommi Tolmunen; Rainer Rauramaa; Heimo Viinamäki; Jussi Kauhanen; Timo Lakka; Leo Niskanen
Leisure-time physical activity, cardiorespiratory fitness and feelings of hopelessness in men.
BMC public health 2009;9():204.
2008: Maarit Valtonen; David E Laaksonen; Tommi Tolmunen; Kristiina Nyyssönen; Heimo Viinamäki; Jussi Kauhanen; Leo Niskanen
Hopelessness -- novel facet of the metabolic syndrome in men.
Scandinavian journal of public health 2008;36(8):795-802.
2008: Soili M Lehto; Tuula Heiskanen; Jukka Hintikka; Leo Niskanen; Heli Koivumaa-Honkanen; Tommi Tolmunen; Kirsi Honkalampi; Heimo Viinamäki
Metabolic syndrome--the impact of depression.
Annals of epidemiology 2008;18(11):871.
2008: V D F de Mello; Marjukka Kolehmainen; Leena Pulkkinen; Ursula S Schwab; Ursula Griebler; David E Laaksonen; Leo Niskanen; Helena Gylling; Mustafa Atalay; Rainer Rauramaa; Matti Uusitupa
Downregulation of genes involved in NFkappaB activation in peripheral blood mononuclear cells after weight loss is associated with the improvement of insulin sensitivity in individuals with the metabolic syndrome: the GENOBIN study.
Diabetologia 2008;51(11):2060-7.
2008: David E Laaksonen; Leo Niskanen; Kristiina Nyyssönen; Timo A Lakka; Jari A Laukkanen; Jukka T Salonen
Dyslipidaemia as a predictor of hypertension in middle-aged men.
European heart journal 2008;29(20):2561-8.
2008: J Petteri Talasniemi; Sirpa Pennanen; Heikki Savolainen; Leo Niskanen; Jyrki Liesivuori
Analytical investigation: assay of D-lactate in diabetic plasma and urine.
Clinical biochemistry 2008;41(13):1099-103.
2008: Seppo Lehto; Jukka Hintikka; Leo Niskanen; Tommi Tolmunen; Heli Koivumaa-Honkanen; Kirsi Honkalampi; Heimo Viinamäki
Low HDL cholesterol associates with major depression in a sample with a 7-year history of depressive symptoms.
Progress in neuro-psychopharmacology & biological psychiatry 2008;32(6):1557-61.
2008: Pekka Mäntyselkä; J Miettola; Leo Niskanen; Esko Kumpusalo
Glucose regulation and chronic pain at multiple sites.
Rheumatology (Oxford, England) 2008;47(8):1235-8.
2008: Jarmo Jääskeläinen; Seija Korhonen; Tiina Kuulasmaa; Sudhir Kurl; Leo Niskanen; Mauno Vanhala; Maritta Hippeläinen; Raimo Voutilainen; Seppo Heinonen
Androgen receptor gene CAG repeat length in women with metabolic syndrome.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2008;24(7):411-6.
2008: Pekka Mäntyselkä; Juhani Miettola; Leo Niskanen; Esko Kumpusalo
Chronic pain, impaired glucose tolerance and diabetes: a community-based study.
Pain 2008;137(1):34-40.
2008: Piia Peura; Janne A Martikainen; Erkki Soini; Taru Hallinen; Leo Niskanen
Cost-effectiveness of statins in the prevention of coronary heart disease events in middle-aged Finnish men.
Current medical research and opinion 2008;24(6):1823-32.
2008: Petteri Kallio; Marjukka Kolehmainen; David E Laaksonen; Leena Pulkkinen; Mustafa Atalay; Hannu M Mykkänen; Matti Uusitupa; Kaisa S Poutanen; Leo Niskanen
Inflammation markers are modulated by responses to diets differing in postprandial insulin responses in individuals with the metabolic syndrome.
The American journal of clinical nutrition 2008;87(5):1497-503.
2008: Tomi Laitinen; Tiina Lyyra-Laitinen; Hanna Huopio; Ilkka Vauhkonen; Toivo Halonen; Juha Hartikainen; Leo Niskanen; Markku Laakso
Electrocardiographic alterations during hyperinsulinemic hypoglycemia in healthy subjects.
Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 2008;13(2):97-105.
2008: Vanessa D F de Mello; Marjukka Kolehmainen; Ursula S Schwab; Ursula Griebler; David E Laaksonen; Leena Pulkkinen; Leo Niskanen; Helena Gylling; Mustafa Atalay; Rainer Rauramaa; Matti Uusitupa
Effect of weight loss on cytokine messenger RNA expression in peripheral blood mononuclear cells of obese subjects with the metabolic syndrome.
Metabolism: clinical and experimental 2008;57(2):192-9.
2008: Marjukka Kolehmainen; Titta Salopuro; Ursula S Schwab; J Kekäläinen; P Kallio; David E Laaksonen; Leena Pulkkinen; Virpi Lindi; Katariina Sivenius; Ursula Griebler; Niina Siitonen; Leo Niskanen; Helena Gylling; Rainer Rauramaa; Matti Uusitupa
Weight reduction modulates expression of genes involved in extracellular matrix and cell death: the GENOBIN study.
International journal of obesity (2005) 2008;32(2):292-303.
2008: Tarja Saharinen; Jukka Hintikka; Leo Niskanen; Jari Kylmä; Kirsi Honkalampi; Merja Nikkonen; Kaisa Haatainen; Heli Koivumaa-Honkanen; Heimo Viinamäki
Health-related quality of life in a population-based sample of men with long-term mental symptoms.
Nordic journal of psychiatry 2008;62(2):106-12.
2008: David E Laaksonen; Leo Niskanen; Hannu Mykkänen; Katri S Juntunen; Ursula Schwab; Marjukka Kolehmainen; Rainer Rauramaa; Jaakko Tuomilehto; Matti Uusitupa
Long-term repeatability of measures of early insulin secretion derived from an intravenous glucose tolerance test and conversion from impaired glucose tolerance to diabetes.
Annals of medicine 2008;40(4):303-11.
2008: Kari Ojala; Eila Repo-Tiihonen; Jari Tiihonen; Leo Niskanen
Statins are effective in treating dyslipidemia among psychiatric patients using second-generation antipsychotic agents.
Journal of psychopharmacology (Oxford, England) 2008;22(1):33-8.
2007: Chaiyasit Sittiwet; Helena Gylling; Merja Hallikainen; Jussi Pihlajamäki; Leena Moilanen; David E Laaksonen; Leo Niskanen; Jyrki J Agren; Markku Laakso; Tatu A Miettinen
Cholesterol metabolism and non-cholesterol sterol distribution in lipoproteins of type 1 diabetes: the effect of improved glycemic control.
Atherosclerosis 2007;194(2):465-72.
2007: Merja Hallikainen; Marjukka Kolehmainen; Ursula S Schwab; David E Laaksonen; Leo Niskanen; Rainer Rauramaa; Jussi Pihlajamäki; Matti Uusitupa; Tatu A Miettinen; Helena Gylling
Serum adipokines are associated with cholesterol metabolism in the metabolic syndrome.
Clinica chimica acta; international journal of clinical chemistry 2007;383(1-2):126-32.
2007: J Saarelainen; Toni Rikkonen; Risto Honkanen; Heikki Kröger; Marjo Tuppurainen; Leo Niskanen; Jukka S Jurvelin
Is discordance in bone measurements affected by body composition or anthropometry? A comparative study between peripheral and central devices.
Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry 2007;10(3):312-8.
2007: Helena Gylling; David E Laaksonen; Mustafa Atalay; Merja Hallikainen; Leo Niskanen; Tatu A Miettinen
Markers of absorption and synthesis of cholesterol in men with type 1 diabetes.
Diabetes/metabolism research and reviews 2007;23(5):372-7.
2007: Petteri Kallio; Marjukka Kolehmainen; David E Laaksonen; Jani Kekäläinen; Titta Salopuro; Katariina Sivenius; Leena Pulkkinen; Hannu M Mykkänen; Leo Niskanen; Matti Uusitupa; Kaisa S Poutanen
Dietary carbohydrate modification induces alterations in gene expression in abdominal subcutaneous adipose tissue in persons with the metabolic syndrome: the FUNGENUT Study.
The American journal of clinical nutrition 2007;85(5):1417-27.
2007: Miika V Heinonen; Leila J Karhunen; Emelia D Chabot; Leena Toppinen; Katri S Juntunen; David E Laaksonen; Maritta Siloaho; Kirsi-Helena Liukkonen; Karl-Heinz Herzig; Leo Niskanen; Hannu M Mykkänen
Plasma ghrelin levels after two high-carbohydrate meals producing different insulin responses in patients with metabolic syndrome.
Regulatory peptides 2007;138(2-3):118-25.
2007: Jouko Järvenpää; Ursula Schwab; Tiina Lappalainen; Mervi Päkkilä; Leo Niskanen; Kari Punnonen; Markku Ryynänen
Fortified mineral water improves folate status and decreases plasma homocysteine concentration in pregnant women.
Journal of perinatal medicine 2007;35(2):108-14.
2006: Merja Hallikainen; Leena Toppinen; Hannu M Mykkänen; Jyrki J Agren; David E Laaksonen; Tatu A Miettinen; Leo Niskanen; Kaisa S Poutanen; Helena Gylling
Interaction between cholesterol and glucose metabolism during dietary carbohydrate modification in subjects with the metabolic syndrome.
The American journal of clinical nutrition 2006;84(6):1385-92.
2006: Tuula H Heiskanen; Leo Niskanen; Jukka Hintikka; Heli Koivumaa-Honkanen; Kirsi Honkalampi; Kaisa Haatainen; Heimo Viinamäki
Metabolic syndrome and depression: a cross-sectional analysis.
The Journal of clinical psychiatry 2006;67(9):1422-7.
2006: Leo Niskanen; David E Laaksonen; Jaana Lindström; Johan G Eriksson; Sirkka Keinänen-Kiukaanniemi; Pirjo Ilanne-Parikka; Sirkka Aunola; Helena Hämäläinen; Jaakko Tuomilehto; Matti Uusitupa
Serum uric acid as a harbinger of metabolic outcome in subjects with impaired glucose tolerance: the Finnish Diabetes Prevention Study.
Diabetes care 2006;29(3):709-11.
2006: Sudhir Kurl; Jari A Laukkanen; Leo Niskanen; David E Laaksonen; Juhani Sivenius; Kristiina Nyyssönen; Jukka T Salonen
Metabolic syndrome and the risk of stroke in middle-aged men.
Stroke; a journal of cerebral circulation 2006;37(3):806-11.
2005: David E Laaksonen; Leena Toppinen; Katri S Juntunen; Karin Autio; Kirsi-Helena Liukkonen; Kaisa S Poutanen; Leo Niskanen; Hannu M Mykkänen
Dietary carbohydrate modification enhances insulin secretion in persons with the metabolic syndrome.
The American journal of clinical nutrition 2005;82(6):1218-27.
2005: David E Laaksonen; Leo Niskanen; Kristiina Nyyssönen; Kari Punnonen; Tomi-Pekka Tuomainen; Jukka T Salonen
C-reactive protein in the prediction of cardiovascular and overall mortality in middle-aged men: a population-based cohort study.
European heart journal 2005;26(17):1783-9.
2005: Ilkka Vauhkonen; Leo Niskanen; Mikael Knip; Leena Moilanen Mykkänen; Steven M Haffner; Matti Uusitupa; Markku Laakso
Subtle hyperproinsulinaemia characterises the defective insulin secretory capacity in offspring of glutamic acid decarboxylase antibody-positive patients with latent autoimmune diabetes mellitus in adults.
European journal of endocrinology / European Federation of Endocrine Societies 2005;153(2):265-73.
2005: Sudhir Kurl; Jari A Laukkanen; Leo Niskanen; Rainer Rauramaa; Tomi-Pekka Tuomainen; Juhani Sivenius; Jukka T Salonen
Cardiac power during exercise and the risk of stroke in men.
Stroke; a journal of cerebral circulation 2005;36(4):820-4.
2005: David E Laaksonen; Leo Niskanen; Kari Punnonen; Kristiina Nyyssönen; Tomi-Pekka Tuomainen; Veli-Pekka Valkonen; Jukka T Salonen
The metabolic syndrome and smoking in relation to hypogonadism in middle-aged men: a prospective cohort study.
The Journal of clinical endocrinology and metabolism 2005;90(2):712-9.
2005: David E Laaksonen; Kristiina Nyyssönen; Leo Niskanen; Tiina H Rissanen; Jukka T Salonen
Prediction of cardiovascular mortality in middle-aged men by dietary and serum linoleic and polyunsaturated fatty acids.
Archives of internal medicine 2005;165(2):193-9.
2005: Auni M Juutilainen; Erkki T Voutilainen; Leena Mykkänen; Leo Niskanen
Plasma aldosterone to renin ratio predicts treatment response in primary aldosteronism: is volume loading needed?
Blood pressure 2005;14(4):245-50.
2005: J Saarelainen; Risto Honkanen; Esko Vanninen; Heikki Kröger; Marjo Tuppurainen; Leo Niskanen; Jukka S Jurvelin
Cross-calibration of Lunar DPX-IQ and DPX dual-energy x-ray densitometers for bone mineral measurements in women: effect of body anthropometry.
Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry 2005;8(3):320-9.
2005: Timo Sane; Timo Tulokas; Paula Nikkanen; Pirjo Heikkilä; Erja Huttunen; Leo Niskanen
[Insulin pump in the treatment of adult age diabetes].
Duodecim; lääketieteellinen aikakauskirja 2005;121(8):839-45.
2005: Jukka Hintikka; Leo Niskanen
[Schizophrenia increases risk of diabetes and cardiovascular diseases].
Duodecim; lääketieteellinen aikakauskirja 2005;121(7):705-7.
2005: David E Laaksonen; Jaana Lindström; Timo A Lakka; Johan G Eriksson; Leo Niskanen; Katja Wikström; Sirkka Aunola; Sirkka Keinänen-Kiukaanniemi; Mauri Laakso; Timo T Valle; Pirjo Ilanne-Parikka; Anne Louheranta; Helena Hämäläinen; Merja Rastas; Virpi Salminen; Zygimantas Cepaitis; Martti Hakumäki; Hannu Kaikkonen; Pirjo Härkönen; Jouko Sundvall; Jaakko Tuomilehto; Matti Uusitupa
Physical activity in the prevention of type 2 diabetes: the Finnish diabetes prevention study.
Diabetes 2005;54(1):158-65.
2004: Katariina Sivenius; Leo Niskanen; Raija Voutilainen-Kaunisto; Markku Laakso; Matti Uusitupa
Aldose reductase gene polymorphisms and susceptibility to microvascular complications in Type 2 diabetes.
Diabetic medicine : a journal of the British Diabetic Association 2004;21(12):1325-33.
2004: Leo Niskanen; David E Laaksonen; Kristiina Nyyssönen; Kari Punnonen; Veli-Pekka Valkonen; Ricardo Fuentes; Tomi-Pekka Tuomainen; Riitta Salonen; Jukka T Salonen
Inflammation, abdominal obesity, and smoking as predictors of hypertension.
Hypertension 2004;44(6):859-65.
2004: Jari A Laukkanen; David E Laaksonen; Leo Niskanen; Eero Pukkala; Anna Hakkarainen; Jukka T Salonen
Metabolic syndrome and the risk of prostate cancer in Finnish men: a population-based study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2004;13(10):1646-50.
2004: Anna-Mari Heikkinen; Leo Niskanen; Jukka A Salmi; Markku Koulu; Ullamari Pesonen; M I J Uusitupa; Marja Komulainen; Marjo Tuppurainen; Heikki Kröger; Jukka S Jurvelin; Seppo Saarikoski
Leucine7 to proline7 polymorphism in prepro-NPY gene and femoral neck bone mineral density in postmenopausal women.
Bone 2004;35(3):589-94.
2004: David E Laaksonen; Jari A Laukkanen; Leo Niskanen; Kristiina Nyyssönen; Tiina H Rissanen; Sari Voutilainen; Eero Pukkala; Anna Hakkarainen; Jukka T Salonen
Serum linoleic and total polyunsaturated fatty acids in relation to prostate and other cancers: a population-based cohort study.
International journal of cancer. Journal international du cancer 2004;111(3):444-50.
2004: David E Laaksonen; Leo Niskanen; Kristiina Nyyssönen; Kari Punnonen; Tomi-Pekka Tuomainen; Veli-Pekka Valkonen; Riitta Salonen; Jukka T Salonen
C-reactive protein and the development of the metabolic syndrome and diabetes in middle-aged men.
Diabetologia 2004;47(8):1403-10.
2004: Katariina Sivenius; Jussi Pihlajamäki; Juhani Partanen; Leo Niskanen; Markku Laakso; Matti Uusitupa
Aldose reductase gene polymorphisms and peripheral nerve function in patients with type 2 diabetes.
Diabetes care 2004;27(8):2021-6.
2004: Leo Niskanen; David E Laaksonen; Kristiina Nyyssönen; Georg Alfthan; Hanna-Maaria Lakka; Timo A Lakka; Jukka T Salonen
Uric acid level as a risk factor for cardiovascular and all-cause mortality in middle-aged men: a prospective cohort study.
Archives of internal medicine 2004;164(14):1546-51.
2004: Tomi Laitinen; Leo Niskanen; Ghislaine Geelen; Esko Länsimies; Juha Hartikainen
Age dependency of cardiovascular autonomic responses to head-up tilt in healthy subjects.
Journal of applied physiology (Bethesda, Md. : 1985) 2004;96(6):2333-40.
2004: David E Laaksonen; Leo Niskanen; Kari Punnonen; Kristiina Nyyssönen; Tomi-Pekka Tuomainen; Veli-Pekka Valkonen; Riitta Salonen; Jukka T Salonen
Testosterone and sex hormone-binding globulin predict the metabolic syndrome and diabetes in middle-aged men.
Diabetes care 2004;27(5):1036-41.
2004: Leo Niskanen; David E Laaksonen; Kari Punnonen; Pertti Mustajoki; Jarmo Kaukua; Aila Rissanen
Changes in sex hormone-binding globulin and testosterone during weight loss and weight maintenance in abdominally obese men with the metabolic syndrome.
Diabetes, obesity & metabolism 2004;6(3):208-15.
2004: Leo Niskanen; Linda Elise Jensen; Jacob Råstam; Lars Nygaard-Pedersen; Knut Erichsen; Jiten P Vora
Randomized, multinational, open-label, 2-period, crossover comparison of biphasic insulin aspart 30 and biphasic insulin lispro 25 and pen devices in adult patients with type 2 diabetes mellitus.
Clinical therapeutics 2004;26(4):531-40.
2004: Anders Niklason; Thomas Hedner; Leo Niskanen; Jan Lanke
Development of diabetes is retarded by ACE inhibition in hypertensive patients--a subanalysis of the Captopril Prevention Project (CAPPP).
Journal of hypertension 2004;22(3):645-52.
2004: Niina S Tapola; Henna M Karvonen; Leo Niskanen; Essi S Sarkkinen
Mineral water fortified with folic acid, vitamins B6, B12, D and calcium improves folate status and decreases plasma homocysteine concentration in men and women.
European journal of clinical nutrition 2004;58(2):376-85.
2004: David E Laaksonen; Leo Niskanen; Hanna-Maaria Lakka; Timo A Lakka; Matti Uusitupa
Epidemiology and treatment of the metabolic syndrome.
Annals of medicine 2004;36(5):332-46.
2004: Leo Niskanen
[Oral drugs for diabetes--update of current use and availability].
Duodecim; lääketieteellinen aikakauskirja 2004;120(8):983-90.
2003: David E Laaksonen; Sakari Kainulainen; Aila Rissanen; Leo Niskanen
Relationships between changes in abdominal fat distribution and insulin sensitivity during a very low calorie diet in abdominally obese men and women.
Nutrition, metabolism, and cardiovascular diseases : NMCD 2003;13(6):349-56.
2003: David E Laaksonen; Leo Niskanen; Kari Punnonen; Kristiina Nyyssönen; Tomi-Pekka Tuomainen; Riitta Salonen; Rainer Rauramaa; Jukka T Salonen
Sex hormones, inflammation and the metabolic syndrome: a population-based study.
European journal of endocrinology / European Federation of Endocrine Societies 2003;149(6):601-8.
2003: Katri S Juntunen; David E Laaksonen; Karin Autio; Leo Niskanen; Jens J Holst; Kari E Savolainen; Kirsi-Helena Liukkonen; Kaisa S Poutanen; Hannu M Mykkänen
Structural differences between rye and wheat breads but not total fiber content may explain the lower postprandial insulin response to rye bread.
The American journal of clinical nutrition 2003;78(5):957-64.
2003: M Juntunen; Leo Niskanen; J Saarelainen; Marjo Tuppurainen; Seppo Saarikoski; Risto Honkanen
Changes in body weight and onset of hypertension in perimenopausal women.
Journal of human hypertension 2003;17(11):775-9.
2003: Tomi Laitinen; Hanna Huopio; Ilkka Vauhkonen; Cyril Camaro; Juha Hartikainen; Markku Laakso; Leo Niskanen
Effects of euglycaemic and hypoglycaemic hyperinsulinaemia on sympathetic and parasympathetic regulation of haemodynamics in healthy subjects.
Clinical science (London, England : 1979) 2003;105(3):315-22.
2003: Päivi Kekäläinen; E Alhava; Esko Vanninen; Leo Niskanen
A pitfall of metaiodobenzylguanidine scan: paraganglioma in close proximity to adrenocortical adenoma.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2003;111(5):294-7.
2003: Katariina Sivenius; Leo Niskanen; Markku Laakso; Matti Uusitupa
A deletion in the alpha2B-adrenergic receptor gene and autonomic nervous function in central obesity.
Obesity research 2003;11(8):962-70.
2003: Timo A Lakka; David E Laaksonen; Hanna-Maaria Lakka; Niko Männikkö; Leo Niskanen; Rainer Rauramaa; Jukka T Salonen
Sedentary lifestyle, poor cardiorespiratory fitness, and the metabolic syndrome.
Medicine and science in sports and exercise 2003;35(8):1279-86.
2003: David E Laaksonen; Hanna-Maaria Lakka; John Lynch; Timo A Lakka; Leo Niskanen; Rainer Rauramaa; Jukka T Salonen; Jussi Kauhanen
Cardiorespiratory fitness and vigorous leisure-time physical activity modify the association of small size at birth with the metabolic syndrome.
Diabetes care 2003;26(7):2156-64.
2003: Tuula Heiskanen; Leo Niskanen; Riitta Lyytikäinen; Pirjo Irmeli Saarinen; Jukka Hintikka
Metabolic syndrome in patients with schizophrenia.
The Journal of clinical psychiatry 2003;64(5):575-9.
2003: Leo Niskanen; Virpi Lindi; Arja T Erkkilä; Katariina Sivenius; Jukka S Luoma; Seppo Ylä-Herttuala; Markku Laakso; M I J Uusitupa
Association of the PRO12ALA polymorphism of the PPAR-gamma2 gene with oxidized low-density lipoprotein and cardiolipin autoantibodies in nondiabetic and type 2 diabetic subjects.
Metabolism: clinical and experimental 2003;52(2):213-7.
2003: David E Laaksonen; Tomi Laitinen; Jonas Schönberg; Aila Rissanen; Leo Niskanen
Weight loss and weight maintenance, ambulatory blood pressure and cardiac autonomic tone in obese persons with the metabolic syndrome.
Journal of hypertension 2003;21(2):371-8.
2003: Katri S Juntunen; David E Laaksonen; Kaisa S Poutanen; Leo Niskanen; Hannu M Mykkänen
High-fiber rye bread and insulin secretion and sensitivity in healthy postmenopausal women.
The American journal of clinical nutrition 2003;77(2):385-91.
2002: Hanna-Maaria Lakka; David E Laaksonen; Timo A Lakka; Leo Niskanen; Esko Kumpusalo; Jaakko Tuomilehto; Jukka T Salonen
The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men.
JAMA : the journal of the American Medical Association 2002;288(21):2709-16.
2002: David E Laaksonen; Hanna-Maaria Lakka; Leo Niskanen; George Kaplan; Jukka T Salonen; Timo A Lakka
Metabolic syndrome and development of diabetes mellitus: application and validation of recently suggested definitions of the metabolic syndrome in a prospective cohort study.
American journal of epidemiology 2002;156(11):1070-7.
2002: Irja Haapala; Anu Hirvonen; Leo Niskanen; Matti Uusitupa; Heikki Kröger; Esko Alhava; Aulikki Nissinen
Anthropometry, bioelectrical impedance and dual-energy X-ray absorptiometry in the assessment of body composition in elderly Finnish women.
Clinical physiology and functional imaging 2002;22(6):383-91.
2002: David E Laaksonen; Hanna-Maaria Lakka; Jukka T Salonen; Leo Niskanen; Rainer Rauramaa; Timo A Lakka
Low levels of leisure-time physical activity and cardiorespiratory fitness predict development of the metabolic syndrome.
Diabetes care 2002;25(9):1612-8.
2002: David E Laaksonen; Timo A Lakka; Hanna-Maaria Lakka; Kristiina Nyyssönen; Tiina H Rissanen; Leo Niskanen; Jukka T Salonen
Serum fatty acid composition predicts development of impaired fasting glycaemia and diabetes in middle-aged men.
Diabetic medicine : a journal of the British Diabetic Association 2002;19(6):456-64.
2002: Ghislaine Geelen; Tomi Laitinen; Juha Hartikainen; Esko Länsimies; Kim Bergström; Leo Niskanen
Gender influence on vasoactive hormones at rest and during a 70 degrees head-up tilt in healthy humans.
Journal of applied physiology (Bethesda, Md. : 1985) 2002;92(4):1401-8.
2002: Seppo Lehto; Leo Niskanen; Matti Suhonen; Tapani Rönnemaa; Pekka Saikku; Markku Laakso
Association between Chlamydia pneumoniae antibodies and intimal calcification in femoral arteries of nondiabetic patients.
Archives of internal medicine 2002;162(5):594-9.
2002: Raija Voutilainen-Kaunisto; Leo Niskanen; Matti Uusitupa; Markku Teräsvirta
Iris transluminance in type 2 diabetes.
Acta ophthalmologica Scandinavica 2002;80(1):64-8.
2002: Katri S Juntunen; Leo Niskanen; Kirsi-Helena Liukkonen; Kaisa S Poutanen; Jens J Holst; Hannu M Mykkänen
Postprandial glucose, insulin, and incretin responses to grain products in healthy subjects.
The American journal of clinical nutrition 2002;75(2):254-62.
2002: Jan Böhm; Leo Niskanen; Raija Tammi; Markku Tammi; Matti Eskelinen; Risto Pirinen; Sinikka Hollmen; Esko Alhava; Veli-Matti Kosma
Hyaluronan expression in differentiated thyroid carcinoma.
The Journal of pathology 2002;196(2):180-5.
2002: Hanna Huopio; Ilkka Vauhkonen; Jorma Komulainen; Leo Niskanen; Timo Otonkoski; Markku Laakso
Carriers of an inactivating beta-cell ATP-sensitive K(+) channel mutation have normal glucose tolerance and insulin sensitivity and appropriate insulin secretion.
Diabetes care 2002;25(1):101-6.
2001: Leo Niskanen; Thomas Hedner; Lennart Hansson; Jan Lanke; Anders Niklason
Reduced cardiovascular morbidity and mortality in hypertensive diabetic patients on first-line therapy with an ACE inhibitor compared with a diuretic/beta-blocker-based treatment regimen: a subanalysis of the Captopril Prevention Project.
Diabetes care 2001;24(12):2091-6.
2001: Katariina Sivenius; Virpi Lindi; Leo Niskanen; Markku Laakso; Matti Uusitupa
Effect of a three-amino acid deletion in the alpha2B-adrenergic receptor gene on long-term body weight change in Finnish non-diabetic and type 2 diabetic subjects.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2001;25(11):1609-14.
2001: Virpi Lindi; Katariina Sivenius; Leo Niskanen; Markku Laakso; M I J Uusitupa
Effect of the Pro12Ala polymorphism of the PPAR-gamma2 gene on long-term weight change in Finnish non-diabetic subjects.
Diabetologia 2001;44(7):925-6.
2001: Raija Voutilainen-Kaunisto; Markku Teräsvirta; Matti Uusitupa; Leo Niskanen
Maculopathy and visual acuity in newly diagnosed type 2 diabetic patients and non-diabetic subjects: a 10-year follow-up study.
Acta ophthalmologica Scandinavica 2001;79(2):163-8.
2001: Jarmo Kaukua; Anu K Turpeinen; Matti Uusitupa; Leo Niskanen
Clustering of cardiovascular risk factors in type 2 diabetes mellitus: prognostic significance and tracking.
Diabetes, obesity & metabolism 2001;3(1):17-23.
2001: Raija Voutilainen-Kaunisto; Markku Teräsvirta; M I Uusitupa; Leo Niskanen
Occurrence and predictors of retinopathy and visual acuity in Type 2 diabetic patients and control subjects. 10-year follow-up from the diagnosis.
Journal of diabetes and its complications 2001;15(1):24-33.
2000: Jan Böhm; Leo Niskanen; K Kiraly; Jari K Kellokoski; Matti Eskelinen; Sinikka Hollmen; Esko Alhava; Veli-Matti Kosma
Expression and prognostic value of alpha-, beta-, and gamma-catenins indifferentiated thyroid carcinoma.
The Journal of clinical endocrinology and metabolism 2000;85(12):4806-11.
2000: Raija Voutilainen-Kaunisto; Markku Teräsvirta; M I Uusitupa; Leo Niskanen
Age-related macular degeneration in newly diagnosed type 2 diabetic patients and control subjects: a 10-year follow-up on evolution, risk factors, and prognostic significance.
Diabetes care 2000;23(11):1672-8.
2000: Jan Böhm; Leo Niskanen; Risto Pirinen; K Kiraly; Jari K Kellokoski; KI Moisio; Matti Eskelinen; Harri Tulla; Sinikka Hollmen; Esko M Alhava; Veli-Matti Kosma
Reduced CD44 standard expression is associated with tumour recurrence and unfavourable outcome in differentiated thyroid carcinoma.
The Journal of pathology 2000;192(3):321-7.
2000: J Rissanen; H Wang; Raija Miettinen; Päivi Kärkkäinen; Päivi Kekäläinen; Leena Mykkänen; Johanna Kuusisto; Pauli Karhapää; Leo Niskanen; Matti Uusitupa; Markku Laakso
Variants in the hepatocyte nuclear factor-1alpha and -4alpha genes in Finnish and Chinese subjects with late-onset type 2 diabetes.
Diabetes care 2000;23(10):1533-8.
2000: David E Laaksonen; Mustafa Atalay; Leo Niskanen; J Mustonen; Chandan K Sen; Timo A Lakka; M I J Uusitupa
Aerobic exercise and the lipid profile in type 1 diabetic men: a randomized controlled trial.
Medicine and science in sports and exercise 2000;32(9):1541-8.
2000: Ilkka Vauhkonen; Leo Niskanen; Leena Mykkänen; Steven M Haffner; M I J Uusitupa; Markku Laakso
Hyperproinsulinemia is not a characteristic feature in the offspring of patients with different phenotypes of type II diabetes.
European journal of endocrinology / European Federation of Endocrine Societies 2000;143(2):251-60.
2000: Leo Niskanen; Matti K Karvonen; RH Valve; Markku Koulu; Ullamari Pesonen; M Mercuri; Rainer Rauramaa; Jari Töyry; Markku Laakso; M I J Uusitupa
Leucine 7 to proline 7 polymorphism in the neuropeptide Y gene is associated with enhanced carotid atherosclerosis in elderly patients with type 2 diabetes and control subjects.
The Journal of clinical endocrinology and metabolism 2000;85(6):2266-9.
2000: Katariina Sivenius; RH Valve; Virpi Lindi; Leo Niskanen; Markku Laakso; Matti Uusitupa
Synergistic effect of polymorphisms in uncoupling protein 1 and beta3-adrenergic receptor genes on long-term body weight change in Finnish type 2 diabetic and non-diabetic control subjects.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2000;24(4):514-9.
2000: Anna-Mari Heikkinen; Heikki Kröger; Leo Niskanen; Marja Komulainen; Markku Ryynänen; Markku Parviainen; Marjo Tuppurainen; Risto Honkanen; Seppo Saarikoski
Does apolipoprotein E genotype relate to BMD and bone markers in postmenopausal women?
Maturitas 2000;34(1):33-41.
2000: Leo Niskanen; Raija Voutilainen-Kaunisto; Markku Teräsvirta; Matti K Karvonen; RH Valve; Ullamari Pesonen; Markku Laakso; M I J Uusitupa; Markku Koulu
Leucine 7 to proline 7 polymorphism in the neuropeptide y gene is associated with retinopathy in type 2 diabetes.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2000;108(3):235-6.
2000: J Rissanen; Ari Markkanen; Päivi Kärkkäinen; Jussi Pihlajamäki; Päivi Kekäläinen; Leena Mykkänen; Johanna Kuusisto; Pauli Karhapää; Leo Niskanen; Markku Laakso
Sulfonylurea receptor 1 gene variants are associated with gestational diabetes and type 2 diabetes but not with altered secretion of insulin.
Diabetes care 2000;23(1):70-3.
2000: Ilkka Vauhkonen; Leo Niskanen; Mikael Knip; J Ilonen; Esko Vanninen; Sakari Kainulainen; Matti Uusitupa; Markku Laakso
Impaired insulin secretion in non-diabetic offspring of probands with latent autoimmune diabetes mellitus in adults.
Diabetologia 2000;43(1):69-78.
1999: Jan Böhm; Veli-Matti Kosma; Matti Eskelinen; Sinikka Hollmen; Minna M Niskanen; Harri Tulla; Esko Alhava; Leo Niskanen
Non-suppressed thyrotropin and elevated thyroglobulin are independent predictors of recurrence in differentiated thyroid carcinoma.
European journal of endocrinology / European Federation of Endocrine Societies 1999;141(5):460-7.
1999: MH Korhonen; H Litmanen; Rainer Rauramaa; Sami Väisänen; Leo Niskanen; Matti Uusitupa
Adherence to the salt restriction diet among people with mildly elevated blood pressure.
European journal of clinical nutrition 1999;53(11):880-5.
1999: Tomi Laitinen; Ilkka Vauhkonen; Leo Niskanen; Juha E K Hartikainen; Esko Länsimies; M I J Uusitupa; Markku Laakso
Power spectral analysis of heart rate variability during hyperinsulinemia in nondiabetic offspring of type 2 diabetic patients: evidence for possible early autonomic dysfunction in insulin-resistant subjects.
Diabetes 1999;48(6):1295-9.
1999: Tomi Laitinen; Juha Hartikainen; Leo Niskanen; Ghislaine Geelen; Esko Länsimies
Sympathovagal balance is major determinant of short-term blood pressure variability in healthy subjects.
The American journal of physiology 1999;276(4 Pt 2):H1245-52.
1999: Lennart Hansson; Lars H Lindholm; Leo Niskanen; Jan Lanke; Thomas Hedner; Anders Niklason; K Luomanmäki; Björn Dahlöf; Ulf de Faire; C Mörlin; Bengt E Karlberg; PO Wester; J E Björck
Effect of angiotensin-converting-enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: the Captopril Prevention Project (CAPPP) randomised trial.
Lancet 1999;353(9153):611-6.
1999: Anna-Mari Heikkinen; Leo Niskanen; Markku Ryynänen; Marja Komulainen; Marjo Tuppurainen; Markku Parviainen; Seppo Saarikoski
Is the response of serum lipids and lipoproteins to postmenopausal hormone replacement therapy modified by ApoE genotype?
Arteriosclerosis, thrombosis, and vascular biology 1999;19(2):402-7.
1999: Leo Niskanen; Matti Uusitupa; Markku Laakso
[Drug therapy of hyperglycemia and the prognosis of adult-onset diabetes mellitus].
Duodecim; lääketieteellinen aikakauskirja 1999;115(10):1122-4.
1998: Ilkka Vauhkonen; Leo Niskanen; Steven M Haffner; Sakari Kainulainen; Matti Uusitupa; Markku Laakso
Insulin resistant phenotype is associated with high serum leptin levels in offspring of patients with non-insulin-dependent diabetes mellitus.
European journal of endocrinology / European Federation of Endocrine Societies 1998;139(6):598-604.
1998: Leo Niskanen; Anu K Turpeinen; Ilkka M Penttilä; M I Uusitupa
Hyperglycemia and compositional lipoprotein abnormalities as predictors of cardiovascular mortality in type 2 diabetes: a 15-year follow-up from the time of diagnosis.
Diabetes care 1998;21(11):1861-9.
1998: Anna-Mari Heikkinen; Leo Niskanen; S Ylä-Herttuala; J Luoma; Marjo Tuppurainen; Marja Komulainen; Seppo Saarikoski
Postmenopausal hormone replacement therapy and autoantibodies against oxidized LDL.
Maturitas 1998;29(2):155-61.
1998: S Lehto; Leo Niskanen; T Rönnemaa; Markku Laakso
Serum uric acid is a strong predictor of stroke in patients with non-insulin-dependent diabetes mellitus.
Stroke; a journal of cerebral circulation 1998;29(3):635-9.
1998: Tomi Laitinen; Juha Hartikainen; Esko Vanninen; Leo Niskanen; Ghislaine Geelen; Esko Länsimies
Age and gender dependency of baroreflex sensitivity in healthy subjects.
Journal of applied physiology (Bethesda, Md. : 1985) 1998;84(2):576-83.
1998: Ilkka Vauhkonen; Leo Niskanen; Esko Vanninen; Sakari Kainulainen; Matti Uusitupa; Markku Laakso
Defects in insulin secretion and insulin action in non-insulin-dependent diabetes mellitus are inherited. Metabolic studies on offspring of diabetic probands.
The Journal of clinical investigation 1998;101(1):86-96.
1998: Anna-Mari Heikkinen; Markku Parviainen; Marjo Tuppurainen; Leo Niskanen; Marja Komulainen; Seppo Saarikoski
Effects of postmenopausal hormone replacement therapy with and without vitamin D3 on circulating levels of 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D.
Calcified tissue international 1998;62(1):26-30.
1997: Hannele Yki-Järvinen; L Ryysy; M Kauppila; Erkki Kujansuu; Jari Lahti; T Marjanen; Leo Niskanen; S Rajala; Sirpa Salo; P Seppälä; Timo Tulokas; J Viikari; Marja-Riitta Taskinen
Effect of obesity on the response to insulin therapy in noninsulin-dependent diabetes mellitus.
The Journal of clinical endocrinology and metabolism 1997;82(12):4037-43.
1997: Lennart Hansson; Thomas Hedner; L Lindholm; Anders Niklason; K Luomanmäki; Leo Niskanen; Jan Lanke; Björn Dahlöf; Ulf de Faire; C Mörlin; Bengt E Karlberg; PO Wester; J E Björck
The Captopril Prevention Project (CAPPP) in hypertension--baseline data and current status.
Blood pressure 1997;6(6):365-7.
1997: Anna-Mari Heikkinen; Marjo Tuppurainen; Leo Niskanen; Marja Komulainen; I Penttilä; Seppo Saarikoski
Long-term vitamin D3 supplementation may have adverse effects on serum lipids during postmenopausal hormone replacement therapy.
European journal of endocrinology / European Federation of Endocrine Societies 1997;137(5):495-502.
1997: Ilkka Vauhkonen; Leo Niskanen; M Ryynänen; R Voutilainen; J Partanen; Jari Töyry; M Mercuri; Rainer Rauramaa; Matti Uusitupa
Divergent association of apolipoprotein E polymorphism with vascular disease in patients with NIDDM and control subjects.
Diabetic medicine : a journal of the British Diabetic Association 1997;14(9):748-56.
1997: Jari Töyry; Leo Niskanen; M J Mäntysaari; Esko Länsimies; Steven M Haffner; H J Miettinen; M I J Uusitupa
Do high proinsulin and C-peptide levels play a role in autonomic nervous dysfunction?: Power spectral analysis in patients with non-insulin-dependent diabetes and nondiabetic subjects.
Circulation 1997;96(4):1185-91.
1997: Jari Töyry; J V Partanen; Leo Niskanen; Esko Länsimies; M I J Uusitupa
Divergent development of autonomic and peripheral somatic neuropathies in NIDDM.
Diabetologia 1997;40(8):953-8.
1997: Anna-Mari Heikkinen; Markku Parviainen; Leo Niskanen; Marja Komulainen; Marjo Tuppurainen; Heikki Kröger; Seppo Saarikoski
Biochemical bone markers and bone mineral density during postmenopausal hormone replacement therapy with and without vitamin D3: a prospective, controlled, randomized study.
The Journal of clinical endocrinology and metabolism 1997;82(8):2476-82.
1997: Leo Niskanen; Steven M Haffner; Leila J Karhunen; Anu K Turpeinen; H Miettinen; M I J Uusitupa
Serum leptin in obesity is related to gender and body fat topography but does not predict successful weight loss.
European journal of endocrinology / European Federation of Endocrine Societies 1997;137(1):61-7.
1997: Leo Niskanen; Ursula S Schwab; Essi S Sarkkinen; Tom Krusius; Elina Vahtera; M I J Uusitupa
Effects of dietary fat modification on fibrinogen, factor VII, and plasminogen activator inhibitor-1 activity in subjects with impaired glucose tolerance.
Metabolism: clinical and experimental 1997;46(6):666-72.
1997: Leo Niskanen; Steven M Haffner; Leila J Karhunen; Anu K Turpeinen; H Miettinen; M I J Uusitupa
Serum leptin in relation to resting energy expenditure and fuel metabolism in obese subjects.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1997;21(4):309-13.
1997: Anu K Turpeinen; Steven M Haffner; Anne Louheranta; Leo Niskanen; H Miettinen; M I J Uusitupa
Serum leptin in subjects with impaired glucose tolerance in relation to insulin sensitivity and first-phase insulin response.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1997;21(4):284-7.
1996: Leo Niskanen; Rainer Rauramaa; H Miettinen; Steven M Haffner; M Mercuri; Matti Uusitupa
Carotid artery intima-media thickness in elderly patients with NIDDM and in nondiabetic subjects.
Stroke; a journal of cerebral circulation 1996;27(11):1986-92.
1996: Essi S Sarkkinen; Ursula S Schwab; Leo Niskanen; M Hannuksela; Markku Savolainen; K Kervinen; A Kesäniemi; M I J Uusitupa
The effects of monounsaturated-fat enriched diet and polyunsaturated-fat enriched diet on lipid and glucose metabolism in subjects with impaired glucose tolerance.
European journal of clinical nutrition 1996;50(9):592-8.
1996: Jari Töyry; Leo Niskanen; Esko Länsimies; K P Partanen; M I J Uusitupa
Autonomic neuropathy predicts the development of stroke in patients with non-insulin-dependent diabetes mellitus.
Stroke; a journal of cerebral circulation 1996;27(8):1316-8.
1996: Seppo Lehto; Leo Niskanen; M Suhonen; T Rönnemaa; Markku Laakso
Medial artery calcification. A neglected harbinger of cardiovascular complications in non-insulin-dependent diabetes mellitus.
Arteriosclerosis, thrombosis, and vascular biology 1996;16(8):978-83.
1996: M I J Uusitupa; Leila J Karhunen; Aila Rissanen; A Franssila-Kallunki; Leo Niskanen; K Kervinen; Y A Kesäniemi
Apolipoprotein E phenotype modifies metabolic and hemodynamic abnormalities related to central obesity in women.
The American journal of clinical nutrition 1996;64(2):131-6.
1996: David E Laaksonen; Mustafa Atalay; Leo Niskanen; Matti Uusitupa; Osmo Hänninen; Chandan K Sen
Increased resting and exercise-induced oxidative stress in young IDDM men.
Diabetes care 1996;19(6):569-74.
1996: Matti Uusitupa; M Korhonen; H Litmanen; Leo Niskanen; Sami Väisänen; Rainer Rauramaa
Effects of moderate salt restriction alone and in combination with cilazapril on office and ambulatory blood pressure.
Journal of human hypertension 1996;10(5):319-26.
1996: Leo Niskanen; I Penttilã; M Parviainen; M I J Uusitupa
Evolution, risk factors, and prognostic implications of albuminuria in NIDDM.
Diabetes care 1996;19(5):486-93.
1996: Jari Töyry; Leo Niskanen; M J Mäntysaari; Esko Länsimies; M I J Uusitupa
Occurrence, predictors, and clinical significance of autonomic neuropathy in NIDDM. Ten-year follow-up from the diagnosis.
Diabetes 1996;45(3):308-15.
1996: Leo Niskanen; Matti Uusitupa; H Sarlund; O Siitonen; L Paljärvi; Markku Laakso
The effects of weight loss on insulin sensitivity, skeletal muscle composition and capillary density in obese non-diabetic subjects.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1996;20(2):154-60.
1996: Leila J Karhunen; RI Lappalainen; Leo Niskanen; Anu K Turpeinen; M I J Uusitupa
Determinants of the cephalic-phase insulin response in obese nondiabetic subjects.
Metabolism: clinical and experimental 1996;45(2):168-73.
1995: Leo Niskanen; T Tuomi; J Karjalainen; L C Groop; M I J Uusitupa
GAD antibodies in NIDDM. Ten-year follow-up from the diagnosis.
Diabetes care 1995;18(12):1557-65.
1995: Leo Niskanen; J T Salonen; Kristiina Nyyssönen; M I J Uusitupa
Plasma lipid peroxidation and hyperglycaemia: a connection through hyperinsulinaemia?
Diabetic medicine : a journal of the British Diabetic Association 1995;12(9):802-8.
1995: Leo Niskanen; H Sarlund; Markku Laakso
Metabolic defects in persistent impaired glucose tolerance are related to the family history of non-insulin-dependent diabetes mellitus.
Metabolism: clinical and experimental 1995;44(8):1099-104.
1995: J Partanen; Leo Niskanen; J Lehtinen; E Mervaala; O Siitonen; Matti Uusitupa
Natural history of peripheral neuropathy in patients with non-insulin-dependent diabetes mellitus.
The New England journal of medicine 1995;333(2):89-94.
1995: M I J Uusitupa; Leo Niskanen
Hyperglycemia and cardiovascular risk in NIDDM.
Diabetes care 1995;18(6):884-5.
1995: Ursula S Schwab; Leo Niskanen; H M Maliranta; Markku Savolainen; Y A Kesäniemi; M I J Uusitupa
Lauric and palmitic acid-enriched diets have minimal impact on serum lipid and lipoprotein concentrations and glucose metabolism in healthy young women.
The Journal of nutrition 1995;125(3):466-73.
1994: Leo Niskanen; O Siitonen; M Suhonen; M I J Uusitupa
Medial artery calcification predicts cardiovascular mortality in patients with NIDDM.
Diabetes care 1994;17(11):1252-6.
1994: Leo Niskanen; J Karjalainen; O Siitonen; Matti Uusitupa
Metabolic evolution of type 2 diabetes: a 10-year follow-up from the time of diagnosis.
Journal of internal medicine 1994;236(3):263-70.
1993: Leo Niskanen; Markku Laakso
Insulin resistance is related to albuminuria in patients with type II (non-insulin-dependent) diabetes mellitus.
Metabolism: clinical and experimental 1993;42(12):1541-5.
1993: M I J Uusitupa; Leo Niskanen; O Siitonen; E Voutilainen; Kalevi Pyörälä
Ten-year cardiovascular mortality in relation to risk factors and abnormalities in lipoprotein composition in type 2 (non-insulin-dependent) diabetic and non-diabetic subjects.
Diabetologia 1993;36(11):1175-84.
1993: Leo Niskanen; R Voutilainen; M Teräsvirta; J Lehtinen; A M Teppo; L Groop; Matti Uusitupa
A prospective study of clinical and metabolic associates of proteinuria in patients with type 2 diabetes mellitus.
Diabetic medicine : a journal of the British Diabetic Association 1993;10(6):543-9.
1993: Leo Niskanen; M Piirainen; M Koljonen; Matti Uusitupa
Resting energy expenditure in relation to energy intake in patients with Alzheimer's disease, multi-infarct dementia and in control women.
Age and ageing 1993;22(2):132-7.
1993: J M Lehtinen; Leo Niskanen; K Hyvönen; O Siitonen; Matti Uusitupa
Nerve function and its determinants in patients with newly-diagnosed type 2 (non-insulin-dependent) diabetes mellitus and in control subjects--a 5-year follow-up.
Diabetologia 1993;36(1):68-72.
1992: Leo Niskanen; J Lahti; Matti Uusitupa
Morning or bed-time insulin with or without glibenclamide in elderly type 2 diabetic patients unresponsive to oral antidiabetic agents.
Diabetes research and clinical practice 1992;18(3):185-90.
1992: Leo Niskanen; O Siitonen; J Karjalainen; Matti Uusitupa
Hyperglycaemic symptoms before diagnosis of non-insulin-dependent (type 2) diabetes mellitus in relation to 5-year outcome.
Journal of internal medicine 1992;231(4):397-402.
1991: Leo Niskanen; M I J Uusitupa; Kalevi Pyörälä
The relationship of hyperinsulinaemia to the development of hypertension in type 2 diabetic patients and in non-diabetic subjects.
Journal of human hypertension 1991;5(3):155-9.
1991: Leo Niskanen; J Karjalainen; H Sarlund; O Siitonen; Matti Uusitupa
Five-year follow-up of islet cell antibodies in type 2 (non-insulin-dependent) diabetes mellitus.
Diabetologia 1991;34(6):402-8.
1990: Leo Niskanen; M Suhonen; O Siitonen; J M Lehtinen; M I J Uusitupa
Aortic and lower limb artery calcification in type 2 (non-insulin-dependent) diabetic patients and non-diabetic control subjects. A five year follow-up study.
Atherosclerosis 1990;84(1):61-71.
1990: M I J Uusitupa; Leo Niskanen; O Siitonen; E Voutilainen; Kalevi Pyörälä
5-year incidence of atherosclerotic vascular disease in relation to general risk factors, insulin level, and abnormalities in lipoprotein composition in non-insulin-dependent diabetic and nondiabetic subjects.
Circulation 1990;82(1):27-36.
1990: Leo Niskanen; Matti Uusitupa; H Sarlund; O Siitonen; E Voutilainen; I Penttilä; Kalevi Pyörälä
Microalbuminuria predicts the development of serum lipoprotein abnormalities favouring atherogenesis in newly diagnosed type 2 (non-insulin-dependent) diabetic patients.
Diabetologia 1990;33(4):237-43.
1990: Leo Niskanen; M I J Uusitupa; H Sarlund; O Siitonen; Kalevi Pyörälä
Five-year follow-up study on plasma insulin levels in newly diagnosed NIDDM patients and nondiabetic subjects.
Diabetes care 1990;13(1):41-8.
1989: Leo Niskanen; Harri Tulla; J Fräki; Kari U O Tahvanainen
Compartment syndrome as a late complication of eosinophilic fasciitis.
The Journal of rheumatology 1989;16(10):1364-5.