Poul Nissen

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TOP 3
Boesen Thomas; Nissen Poul
V for victory--a V1-ATPase structure revealed.
Toustrup-Jensen Mads S; Holm Rikke; Einholm Anja Pernille; Schack Vivien Rodacker; Morth J Preben; Nissen Poul; Andersen Jens Peter; Vilsen Bente
The C terminus of Na+,K+-ATPase controls Na+ affinity on both sides of the membrane through Arg935.
Nissen Poul
One way for the gastric proton pump.

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All Publications

2009: Boesen Thomas; Nissen Poul
V for victory--a V1-ATPase structure revealed.
EMBO reports 2009;10(11):1211-2.
2009: Toustrup-Jensen Mads S; Holm Rikke; Einholm Anja Pernille; Schack Vivien Rodacker; Morth J Preben; Nissen Poul; Andersen Jens Peter; Vilsen Bente
The C terminus of Na+,K+-ATPase controls Na+ affinity on both sides of the membrane through Arg935.
The Journal of biological chemistry 2009;284(28):18715-25.
2009: Nissen Poul
One way for the gastric proton pump.
The EMBO journal 2009;28(11):1535-6.
2009: Laursen Mette; Bublitz Maike; Moncoq Karine; Olesen Claus; Møller Jesper Vuust; Young Howard S; Nissen Poul; Morth J Preben
Cyclopiazonic acid is complexed to a divalent metal ion when bound to the sarcoplasmic reticulum Ca2+-ATPase.
The Journal of biological chemistry 2009;284(20):13513-8.
2009: Yatime Laure; Buch-Pedersen Morten J; Musgaard Maria; Morth J Preben; Lund Winther Anne-Marie; Pedersen Bjørn P; Olesen Claus; Andersen Jens Peter; Vilsen Bente; Schiøtt Birgit; Palmgren Michael G; Møller Jesper V; Nissen Poul; Fedosova Natalya
P-type ATPases as drug targets: tools for medicine and science.
Biochimica et biophysica acta 2009;1787(4):207-20.
2009: Quistgaard Esben M; Madsen Peder; Grøftehauge Morten K; Nissen Poul; Petersen Claus M; Thirup Søren S
Ligands bind to Sortilin in the tunnel of a ten-bladed beta-propeller domain.
Nature structural & molecular biology 2009;16(1):96-8.
2009: Buch-Pedersen M J; Pedersen B P; Veierskov B; Nissen P; Palmgren M G
Protons and how they are transported by proton pumps.
Pflügers Archiv : European journal of physiology 2009;457(3):573-9.
2008: Schack Vivien Rodacker; Morth Jens Preben; Toustrup-Jensen Mads S; Anthonisen Anne Nyholm; Nissen Poul; Andersen Jens Peter; Vilsen Bente
Identification and function of a cytoplasmic K+ site of the Na+, K+ -ATPase.
The Journal of biological chemistry 2008;283(41):27982-90.
2008: Sengupta Jayati; Nilsson Jakob; Gursky Richard; Kjeldgaard Morten; Nissen Poul; Frank Joachim
Visualization of the eEF2-80S ribosome transition-state complex by cryo-electron microscopy.
Journal of molecular biology 2008;382(1):179-87.
2007: Pedersen Bjørn P; Buch-Pedersen Morten J; Morth J Preben; Palmgren Michael G; Nissen Poul
Crystal structure of the plasma membrane proton pump.
Nature 2007;450(7172):1111-4.
2007: Morth J Preben; Pedersen Bjørn P; Toustrup-Jensen Mads S; Sørensen Thomas L-M; Petersen Janne; Andersen Jens Peter; Vilsen Bente; Nissen Poul
Crystal structure of the sodium-potassium pump.
Nature 2007;450(7172):1043-9.
2007: Olesen Claus; Picard Martin; Winther Anne-Marie Lund; Gyrup Claus; Morth J Preben; Oxvig Claus; Møller Jesper Vuust; Nissen Poul
The structural basis of calcium transport by the calcium pump.
Nature 2007;450(7172):1036-42.
2007: Nilsson Jakob; Sengupta Jayati; Gursky Richard; Nissen Poul; Frank Joachim
Comparison of fungal 80 S ribosomes by cryo-EM reveals diversity in structure and conformation of rRNA expansion segments.
Journal of molecular biology 2007;369(2):429-38.
2007: Taylor Derek J; Nilsson Jakob; Merrill A Rod; Andersen Gregers Rom; Nissen Poul; Frank Joachim
Structures of modified eEF2 80S ribosome complexes reveal the role of GTP hydrolysis in translocation.
The EMBO journal 2007;26(9):2421-31.
2007: Picard Martin; Jensen Anne-Marie Lund; Sørensen Thomas L-M; Champeil Philippe; Møller Jesper Vuust; Nissen Poul
Ca2+ versus Mg2+ coordination at the nucleotide-binding site of the sarcoplasmic reticulum Ca2+-ATPase.
Journal of molecular biology 2007;368(1):1-7.
2006: Parmeggiani Andrea; Nissen Poul
Elongation factor Tu-targeted antibiotics: four different structures, two mechanisms of action.
FEBS letters 2006;580(19):4576-81.
2006: Morth J Preben; Sørensen Thomas Lykke Møller; Nissen Poul
Membrane's Eleven: heavy-atom derivatives of membrane-protein crystals.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 8):877-82.
2006: Sørensen Thomas Lykke-Møller; Olesen Claus; Jensen Anne-Marie Lund; Møller Jesper Vuust; Nissen Poul
Crystals of sarcoplasmic reticulum Ca(2+)-ATPase.
Journal of biotechnology 2006;124(4):704-16.
2006: Parmeggiani Andrea; Krab Ivo M; Okamura Sumio; Nielsen Rikke C; Nyborg Jens; Nissen Poul
Structural basis of the action of pulvomycin and GE2270 A on elongation factor Tu.
Biochemistry 2006;45(22):6846-57.
2006: Jensen Anne-Marie Lund; Sørensen Thomas Lykke-Møller; Olesen Claus; Møller Jesper Vuust; Nissen Poul
Modulatory and catalytic modes of ATP binding by the calcium pump.
The EMBO journal 2006;25(11):2305-14.
2006: Søhoel Helmer; Jensen Anne-Marie Lund; Møller Jesper V; Nissen Poul; Denmeade Samuel R; Isaacs John T; Olsen Carl Erik; Christensen S Brøgger
Natural products as starting materials for development of second-generation SERCA inhibitors targeted towards prostate cancer cells.
Bioorganic & medicinal chemistry 2006;14(8):2810-5.
2006: Parmeggiani Andrea; Krab Ivo M; Watanabe Toshihiko; Nielsen Rikke C; Dahlberg Caroline; Nyborg Jens; Nissen Poul
Enacyloxin IIa pinpoints a binding pocket of elongation factor Tu for development of novel antibiotics.
The Journal of biological chemistry 2006;281(5):2893-900.
2005: Møller Jesper Vuust; Olesen Claus; Jensen Anne-Marie Lund; Nissen Poul
The structural basis for coupling of Ca2+ transport to ATP hydrolysis by the sarcoplasmic reticulum Ca2+-ATPase.
Journal of bioenergetics and biomembranes 2005;37(6):359-64.
2005: Jidenko Marie; Nielsen Rikke C; Sørensen Thomas Lykke-Møller; Møller Jesper V; le Maire Marc; Nissen Poul; Jaxel Christine
Crystallization of a mammalian membrane protein overexpressed in Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(33):11687-91.
2005: Møller Jesper V; Nissen Poul; Sørensen Thomas L-M; le Maire Marc
Transport mechanism of the sarcoplasmic reticulum Ca2+ -ATPase pump.
Current opinion in structural biology 2005;15(4):387-93.
2005: Nilsson Jakob; Nissen Poul
Elongation factors on the ribosome.
Current opinion in structural biology 2005;15(3):349-54.
2005: Brodersen Ditlev E; Nissen Poul
The social life of ribosomal proteins.
The FEBS journal 2005;272(9):2098-108.
2004: Olesen Claus; Sørensen Thomas Lykke-Møller; Nielsen Rikke Christina; Møller Jesper Vuust; Nissen Poul
Dephosphorylation of the calcium pump coupled to counterion occlusion.
Science (New York, N.Y.) 2004;306(5705):2251-5.
2004: Nilsson Jakob; Sengupta Jayati; Frank Joachim; Nissen Poul
Regulation of eukaryotic translation by the RACK1 protein: a platform for signalling molecules on the ribosome.
EMBO reports 2004;5(12):1137-41.
2004: Sørensen Thomas Lykke-Møller; Clausen Johannes D; Jensen Anne-Marie Lund; Vilsen Bente; Møller Jesper Vuust; Andersen Jens Peter; Nissen Poul
Localization of a K+ -binding site involved in dephosphorylation of the sarcoplasmic reticulum Ca2+ -ATPase.
The Journal of biological chemistry 2004;279(45):46355-8.
2004: Sengupta Jayati; Nilsson Jakob; Gursky Richard; Spahn Christian M T; Nissen Poul; Frank Joachim
Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM.
Nature structural & molecular biology 2004;11(10):957-62.
2004: Sørensen Thomas Lykke-Møller; Møller Jesper Vuust; Nissen Poul
Phosphoryl transfer and calcium ion occlusion in the calcium pump.
Science (New York, N.Y.) 2004;304(5677):1672-5.
2003: Valle Mikel; Zavialov Andrey; Li Wen; Stagg Scott M; Sengupta Jayati; Nielsen Rikke C; Nissen Poul; Harvey Stephen C; Ehrenberg Måns; Frank Joachim
Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron microscopy.
Nature structural biology 2003;10(11):899-906.
2003: Andersen Gregers R; Nissen Poul; Nyborg Jens
Elongation factors in protein biosynthesis.
Trends in biochemical sciences 2003;28(8):434-41.
2003: Jørgensen Rene; Ortiz Pedro A; Carr-Schmid Anne; Nissen Poul; Kinzy Terri Goss; Andersen Gregers Rom
Two crystal structures demonstrate large conformational changes in the eukaryotic ribosomal translocase.
Nature structural biology 2003;10(5):379-85.
2000: Nissen P; Kjeldgaard M; Nyborg J
Macromolecular mimicry.
The EMBO journal 2000;19(4):489-95.
1999: Nissen P; Thirup S; Kjeldgaard M; Nyborg J
The crystal structure of Cys-tRNACys-EF-Tu-GDPNP reveals general and specific features in the ternary complex and in tRNA.
Structure (London, England : 1993) 1999;7(2):143-56.
1998: Bilgin N; Ehrenberg M; Ebel C; Zaccai G; Sayers Z; Koch M H; Svergun D I; Barberato C; Volkov V; Nissen P; Nyborg J
Solution structure of the ternary complex between aminoacyl-tRNA, elongation factor Tu, and guanosine triphosphate.
Biochemistry 1998;37(22):8163-72.
1997: Nyborg J; Nissen P; Kjeldgaard M; Thirup S; Polekhina G; Clark B F; Reshetnikova L
Macromolecular mimicry in protein biosynthesis.
Folding & design 1997;2(3):S7-11.
1996: Kristensen O; Reshetnikova L; Nissen P; Siboska G; Thirup S; Nyborg J
Isolation, crystallization and X-ray analysis of the quaternary complex of Phe-tRNA(Phe), EF-Tu, a GTP analog and kirromycin.
FEBS letters 1996;399(1-2):59-62.
1996: Polekhina G; Thirup S; Kjeldgaard M; Nissen P; Lippmann C; Nyborg J
Helix unwinding in the effector region of elongation factor EF-Tu-GDP.
Structure (London, England : 1993) 1996;4(10):1141-51.
1996: Nyborg J; Nissen P; Kjeldgaard M; Thirup S; Polekhina G; Clark B F
Structure of the ternary complex of EF-Tu: macromolecular mimicry in translation.
Trends in biochemical sciences 1996;21(3):81-2.
1996: Nissen P; Kjeldgaard M; Thirup S; Clark B F; Nyborg J
The ternary complex of aminoacylated tRNA and EF-Tu-GTP. Recognition of a bond and a fold.
Biochimie 1996;78(11-12):921-33.
1995: Nissen P; Kjeldgaard M; Thirup S; Polekhina G; Reshetnikova L; Clark B F; Nyborg J
Crystal structure of the ternary complex of Phe-tRNAPhe, EF-Tu, and a GTP analog.
Science (New York, N.Y.) 1995;270(5241):1464-72.
1994: Nissen P; Reshetnikova L; Siboska G; Polekhina G; Thirup S; Kjeldgaard M; Clark B F; Nyborg J
Purification and crystallization of the ternary complex of elongation factor Tu:GTP and Phe-tRNA(Phe).
FEBS letters 1994;356(2-3):165-8.
1993: Kjeldgaard M; Nissen P; Thirup S; Nyborg J
The crystal structure of elongation factor EF-Tu from Thermus aquaticus in the GTP conformation.
Structure (London, England : 1993) 1993;1(1):35-50.

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Poul Nissen

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