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Peter Nixon

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Peter F Nixon; Lindsay Jordan; Craig ZIMITAT; Stephen E Rose; Fernando Zelaya
Choroid plexus dysfunction: the initial event in the pathogenesis of Wernicke's encephalopathy and ethanol intoxication.
Peter F Nixon
Glutamate export at the choroid plexus in health, thiamin deficiency, and ethanol intoxication: review and hypothesis.
Jennifer A McCourt; Peter F Nixon; Ronald G Duggleby
Thiamin nutrition and catalysis-induced instability of thiamin diphosphate.

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All Publications

2008: Peter F Nixon; Lindsay Jordan; Craig ZIMITAT; Stephen E Rose; Fernando Zelaya
Choroid plexus dysfunction: the initial event in the pathogenesis of Wernicke's encephalopathy and ethanol intoxication.
Alcoholism, clinical and experimental research 2008;32(8):1513-23.
2008: Peter F Nixon
Glutamate export at the choroid plexus in health, thiamin deficiency, and ethanol intoxication: review and hypothesis.
Alcoholism, clinical and experimental research 2008;32(8):1339-49.
2006: Jennifer A McCourt; Peter F Nixon; Ronald G Duggleby
Thiamin nutrition and catalysis-induced instability of thiamin diphosphate.
The British journal of nutrition 2006;96(4):636-8.
2004: Peter F Nixon; Marc Jones; Donald J Winzor
Quantitative description of the interaction between folate and the folate-binding protein from cow's milk.
The Biochemical journal 2004;382(Pt 1):215-21.
2003: Martina L Jones; Tony Treloar; Peter F Nixon
Dietary interactions influence the effects of bovine folate-binding protein on the bioavailability of tetrahydrofolates in rats.
The Journal of nutrition 2003;133(2):489-95.
2002: Martina L Jones; Peter F Nixon
Tetrahydrofolates are greatly stabilized by binding to bovine milk folate-binding protein.
The Journal of nutrition 2002;132(9):2690-4.
2001: Chang-Yi (Charlie) Huang; AK Chang; Peter F Nixon; Ronald G Duggleby
Site-directed mutagenesis of the ionizable groups in the active site of Zymomonas mobilis pyruvate decarboxylase: effect on activity and pH dependence.
European journal of biochemistry / FEBS 2001;268(12):3558-65.
2001: Yong-Ge Wu; S L Widjaja; Chang-Yi (Charlie) Huang; Wei Li; Peter F Nixon; Ronald G Duggleby
Congenital lactic acidosis: evaluation of the properties of the a199t natural variant of human pyruvate dehydrogenase e1alpha by in vitro mutation.
Molecular genetics and metabolism 2001;72(3):269-72.
2001: C Zimitat; Peter F Nixon
Glucose induced IEG expression in the thiamin-deficient rat brain.
Brain research 2001;892(1):218-27.
2000: Yong-Ge Wu; AK Chang; Peter F Nixon; W Li; Ronald G Duggleby
Mutagenesis at asp27 of pyruvate decarboxylase from Zymomonas mobilis. Effect on its ability to form acetoin and acetolactate.
European journal of biochemistry / FEBS 2000;267(21):6493-500.
2000: AK Chang; Peter F Nixon; Ronald G Duggleby
Effects of deletions at the carboxyl terminus of Zymomonas mobilis pyruvate decarboxylase on the kinetic properties and substrate specificity.
Biochemistry 2000;39(31):9430-7.
1999: AK Chang; Peter F Nixon; Ronald G Duggleby
Aspartate-27 and glutamate-473 are involved in catalysis by Zymomonas mobilis pyruvate decarboxylase.
The Biochemical journal 1999;339 ( Pt 2)():255-60.
1999: Craig ZIMITAT; Peter F Nixon
Glucose loading precipitates acute encephalopathy in thiamin-deficient rats.
Metabolic brain disease 1999;14(1):1-20.
1998: Gerhard Schenk; Ronald G Duggleby; Peter F Nixon
Properties and functions of the thiamin diphosphate dependent enzyme transketolase.
The international journal of biochemistry & cell biology 1998;30(12):1297-318.
1998: R Fang; Peter F Nixon; Ronald G Duggleby
Identification of the catalytic glutamate in the E1 component of human pyruvate dehydrogenase.
FEBS letters 1998;437(3):273-7.
1998: L R Jordan; Fernando Zelaya; Stephen E Rose; Adrian J Bower; Graham J Galloway; T Wholohan; Peter F Nixon
Changes in the hippocampus induced by glucose in thiamin deficient rats detected by MRI.
Brain research 1998;791(1-2):347-51.
1998: Gerhard Schenk; Ronald G Duggleby; Peter F Nixon
Heterologous expression of human transketolase.
The international journal of biochemistry & cell biology 1998;30(3):369-78.
1997: Gerhard Schenk; Finian Leeper; R England; Peter F Nixon; Ronald G Duggleby
The role of His113 and His114 in pyruvate decarboxylase from Zymomonas mobilis.
European journal of biochemistry / FEBS 1997;248(1):63-71.
1997: Gerhard Schenk; R Layfield; J M Candy; Ronald G Duggleby; Peter F Nixon
Molecular evolutionary analysis of the thiamine-diphosphate-dependent enzyme, transketolase.
Journal of molecular evolution 1997;44(5):552-72.
1996: J M Candy; J Koga; Peter F Nixon; Ronald G Duggleby
The role of residues glutamate-50 and phenylalanine-496 in Zymomonas mobilis pyruvate decarboxylase.
The Biochemical journal 1996;315 ( Pt 3)():745-51.
1995: Fernando Zelaya; Stephen E Rose; Peter F Nixon; B T Wholohan; Adrian J Bower; C Zimitat; J Schoutrop; David M Doddrell
MRI demonstration of impairment of the blood-CSF barrier by glucose administration to the thiamin-deficient rat brain.
Magnetic resonance imaging 1995;13(4):555-61.
1993: C K Booth; Peter F Nixon
Reconstitution of holotransketolase is by a thiamin-diphosphate-magnesium complex.
European journal of biochemistry / FEBS 1993;218(1):261-5.
1993: Stephen E Rose; Peter F Nixon; Fernando Zelaya; B T Wholohan; Craig ZIMITAT; L N Moxon; Stuart Crozier; Ian M Brereton; David M Doddrell
Application of high field localised in vivo 1H MRS to study biochemical changes in the thiamin deficient rat brain under glucose load.
NMR in biomedicine 1993;6(5):324-8.
1992: Peter F Nixon; Russell Diefenbach; Ronald G Duggleby
Inhibition of transketolase and pyruvate decarboxylase by omeprazole.
Biochemical pharmacology 1992;44(1):177-9.
1992: M Abedinia; R Layfield; S M Jones; Peter F Nixon; J S Mattick
Nucleotide and predicted amino acid sequence of a cDNA clone encoding part of human transketolase.
Biochemical and biophysical research communications 1992;183(3):1159-66.
1992: N M Lapsys; R Layfield; Elizabeth Baker; David F Callen; G R Sutherland; M Abedinia; Peter F Nixon; J S Mattick
Chromosomal location of the human transketolase gene.
Cytogenetics and cell genetics 1992;61(4):274-5.
1991: Peter F Nixon; Ronald G Duggleby
The N-terminal amino acid sequence of yeast transketolase.
Protein sequences & data analysis 1991;4(6):325-6.
1991: J Price; A E Clague; R A Kerr; Peter F Nixon
In thiamine deficiency, activation of erythrocyte transketolase by thiamine in vivo exceeds activation by cofactor in vitro.
Clinica chimica acta; international journal of clinical chemistry 1991;202(1-2):39-45.
1990: Peter F Nixon; J Price; M Norman-Hicks; G M Williams; R A Kerr
The relationship between erythrocyte transketolase activity and the 'TPP effect' in Wernicke's encephalopathy and other thiamine deficiency states.
Clinica chimica acta; international journal of clinical chemistry 1990;192(2):89-98.
1990: Craig ZIMITAT; Jillian J Kril; Clive Harper; Peter F Nixon
Progression of neurological disease in thiamin-deficient rats is enhanced by ethanol.
Alcohol (Fayetteville, N.Y.) 1990;7(6):493-501.
1990: G J Ward; Peter F Nixon
Modulation of pteroylpolyglutamate concentration and length in response to altered folate nutrition in a comprehensive range of rat tissues.
The Journal of nutrition 1990;120(5):476-84.
1989: A Grudzinski; M Waltham; B Ioannoni; J Price; Peter F Nixon
Interactions with hemoglobin: a source of error in measurements of transketolase activity in hemolysates.
Clinica chimica acta; international journal of clinical chemistry 1989;180(3):265-75.
1988: T M Sunethra Atukorala; Ronald G Duggleby; Peter F Nixon
Effects of acetaldehyde upon catalysis by human erythrocyte transketolase.
Biochemical pharmacology 1988;37(10):2100-1.
1988: M C Waltham; J W Holland; Peter F Nixon; Donald J Winzor
Thermodynamic characterization of the interactions of methotrexate with dihydrofolate reductase by quantitative affinity chromatography.
Biochemical pharmacology 1988;37(3):541-5.
1988: M C Waltham; J W Holland; S C Robinson; Donald J Winzor; Peter F Nixon
Direct experimental evidence for competitive inhibition of dihydrofolate reductase by methotrexate.
Biochemical pharmacology 1988;37(3):535-9.
1984: Peter F Nixon; M J Kaczmarek; J Tate; R A Kerr; J Price
An erythrocyte transketolase isoenzyme pattern associated with the Wernicke-Korsakoff syndrome.
European journal of clinical investigation 1984;14(4):278-81.
1984: J Tate; M J Kaczmarek; Peter F Nixon
Stimulation of erythrocyte transketolase by added thiamin diphosphate is pH dependent.
Clinica chimica acta; international journal of clinical chemistry 1984;137(1):81-6.
1983: M J Kaczmarek; Peter F Nixon
Variants of transketolase from human erythrocytes.
Clinica chimica acta; international journal of clinical chemistry 1983;130(3):349-56.