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Omer Njajou

Research Profile

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Hemochromatosis

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Rachel E Ward; Sasa A Zivkovic; Aaron I Vinik; Robert M Boudreau; Tamara B Harris; Anne B Newman; Omer T Njajou; Suzanne Satterfield; Elsa S Strotmeyer
Reproducibility of peroneal motor nerve conduction measurement in older adults.
Omer T Njajou; J L Sanders; R Li; M Nalls; Anne B Newman; Elizabeth H Blackburn; Richard M Cawthon; Steven R Cummings; Tamara B Harris; Wen-Chi Hsueh
Shorter telomeres are associated with obesity and weight gain in the elderly.
Michael M Swarbrick; Christian Vaisse; Maria I Valle; Shi-Hsuan Wu; Joseph M Zmuda; Daniel S Evans; Hélène Favre; Tamara B Harris; Pui-Yan Kwok; Rongling Li; Iva Miljkovic; Omer T Njajou; Wen-Chi Hsueh
Replication and extension of association between common genetic variants in SIM1 and human adiposity.

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All Publications

2013: Rachel E Ward; Sasa A Zivkovic; Aaron I Vinik; Robert M Boudreau; Tamara B Harris; Anne B Newman; Omer T Njajou; Suzanne Satterfield; Elsa S Strotmeyer
Reproducibility of peroneal motor nerve conduction measurement in older adults.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2013;124(3):603-9.
2012: Omer T Njajou; J L Sanders; R Li; M Nalls; Anne B Newman; Elizabeth H Blackburn; Richard M Cawthon; Steven R Cummings; Tamara B Harris; Wen-Chi Hsueh
Shorter telomeres are associated with obesity and weight gain in the elderly.
International journal of obesity (2005) 2012;36(9):1176-9.
2011: Michael M Swarbrick; Christian Vaisse; Maria I Valle; Shi-Hsuan Wu; Joseph M Zmuda; Daniel S Evans; Hélène Favre; Tamara B Harris; Pui-Yan Kwok; Rongling Li; Iva Miljkovic; Omer T Njajou; Wen-Chi Hsueh
Replication and extension of association between common genetic variants in SIM1 and human adiposity.
Obesity (Silver Spring, Md.) 2011;19(12):2394-403.
2011: Daniel S Evans; Soren Snitker; Shih-Hsuan Wu; Aaloke Mody; Omer T Njajou; Michael L Perlis; Philip R Gehrman; Alan R Shuldiner; Wen-Chi Hsueh
Habitual sleep/wake patterns in the Old Order Amish: heritability and association with non-genetic factors.
Sleep 2011;34(5):661-9.
2010: M Carolina Pardo Silva; Omer T Njajou; Behrooz Alizadeh; Albert Hofman; Jacqueline C M Witteman; Cornelia M van Duijn; A Cecile J W Janssens
HFE gene mutations increase the risk of coronary heart disease in women.
European journal of epidemiology 2010;25(9):643-9.
2010: Omer T Njajou; Elizabeth H Blackburn; Ludmila Pawlikowska; Massimo Mangino; Coleen M Damcott; Pui-Yan Kwok; Timothy D Spector; Anne B Newman; Tamara B Harris; Steven R Cummings; Richard M Cawthon; Alan R Shuldiner; AM Valdes; Wen-Chi Hsueh
A common variant in the telomerase RNA component is associated with short telomere length.
PloS one 2010;5(9):e13048.
2009: Omer T Njajou; Alka M Kanaya; Paul Holvoet; Stephanie Connelly; Elsa S Strotmeyer; Tamara B Harris; Steve R Cummings; Wen-Chi Hsueh
Association between oxidized LDL, obesity and type 2 diabetes in a population-based cohort, the Health, Aging and Body Composition Study.
Diabetes/metabolism research and reviews 2009;25(8):733-9.
2009: Omer T Njajou; Wen-Chi Hsueh; Elizabeth H Blackburn; Anne B Newman; Shih-Hsuan Wu; Rongling Li; Eleanor M Simonsick; Tamara M Harris; Steve R Cummings; Richard M Cawthon
Association between telomere length, specific causes of death, and years of healthy life in health, aging, and body composition, a population-based cohort study.
The journals of gerontology. Series A, Biological sciences and medical sciences 2009;64(8):860-4.
2009: Behrooz Alizadeh; Omer T Njajou; M R Millán; Albert Hofman; Monique Breteler; C.M. Duijn
HFE variants, APOE and Alzheimer's disease: findings from the population-based Rotterdam study.
Neurobiology of aging 2009;30(2):330-2.
2007: Behrooz Alizadeh; Omer T Njajou; J M W Hazes; Albert Hofman; P Eline Slagboom; Huibert A P Pols; C.M. Duijn
The H63D variant in the HFE gene predisposes to arthralgia, chondrocalcinosis and osteoarthritis.
Annals of the rheumatic diseases 2007;66(11):1436-42.
2007: Omer T Njajou; Richard M Cawthon; Coleen M Damcott; Shih-Hsuan Wu; Sandy Ott; Michael J Garant; Elizabeth H Blackburn; Braxton D Mitchell; Alan R Shuldiner; Wen-Chi Hsueh
Telomere length is paternally inherited and is associated with parental lifespan.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(29):12135-9.
2007: I A Hoppenbrouwers; L M Pardo Cortes; Yurii Aulchenko; Kees Sintnicolaas; Omer T Njajou; Pieter J L M Snijders; Ben A Oostra; C.M. Duijn; Rogier Q Hintzen
Familial clustering of multiple sclerosis in a Dutch genetic isolate.
Multiple sclerosis (Houndmills, Basingstoke, England) 2007;13(1):17-24.
2007: Nadia A Sutedja; Richard J Sinke; Paul van Vught; Michiel W Van der Linden; J H J Wokke; C.M. Duijn; Omer T Njajou; Yvonne van der Schouw; Jan Veldink; Leonard H Van den Berg
The association between H63D mutations in HFE and amyotrophic lateral sclerosis in a Dutch population.
Archives of neurology 2007;64(1):63-7.
2006: Mojgan Yazdanpanah; Ingrid Rietveld; Joop A M J L Janssen; Omer T Njajou; Albert Hofman; Theo Stijnen; Huibert A P Pols; Steven W J Lamberts; Jacqueline C M Witteman; C.M. Duijn
An insulin-like growth factor-I promoter polymorphism is associated with increased mortality in subjects with myocardial infarction in an elderly Caucasian population.
The American journal of cardiology 2006;97(9):1274-6.
2006: Omer T Njajou; Behrooz Alizadeh; Yurii Aulchenko; M Carola Zillikens; Huibert A P Pols; Ben A Oostra; D W Swinkels; C.M. Duijn
Heritability of serum iron, ferritin and transferrin saturation in a genetically isolated population, the Erasmus Rucphen Family (ERF) Study.
Human heredity 2006;61(4):222-8.
2005: Angela M González-Zuloeta Ladd; Alejandro Arias Vásquez; Fakhredin A Sayed-Tabatabaei; Dorry Boll; Albert Hofman; Omer T Njajou; Bruno H Ch Stricker; C.M. Duijn
Angiotensin-converting enzyme gene insertion/deletion polymorphism and breast cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(9):2143-6.
2005: Behrooz Alizadeh; Omer T Njajou; C Bijkerk; JIMMY MOLYNEUX; S C De Wildt; Albert Hofman; Huibert A P Pols; P Eline Slagboom; C.M. Duijn
Evidence for a role of the genomic region of the gene encoding for the alpha1 chain of type IX collagen (COL9A1) in hip osteoarthritis: A population-based study.
Arthritis and rheumatism 2005;52(5):1437-42.
2004: Behrooz Alizadeh; Omer T Njajou; Jeanine J Houwing-Duistermaat; Gerard de Jong; Jeannette M Vergeer; Albert Hofman; Huibert A P Pols; C.M. Duijn
Does bilirubin protect against hemochromatosis gene (HFE) related mortality?
American journal of medical genetics. Part A 2004;129A(1):39-43.
2004: Aaron Isaacs; Fakhredin A Sayed-Tabatabaei; Omer T Njajou; Jacqueline C M Witteman; C.M. Duijn
The -514 C->T hepatic lipase promoter region polymorphism and plasma lipids: a meta-analysis.
The Journal of clinical endocrinology and metabolism 2004;89(8):3858-63.
2004: Omer T Njajou; Behrooz Alizadeh; C.M. Duijn
Is genetic screening for hemochromatosis worthwhile?
European journal of epidemiology 2004;19(2):101-8.
2003: Marieke C J Dekker; Patricia C Giesbergen; Omer T Njajou; John C van Swieten; Albert Hofman; Monique Breteler; C.M. Duijn
Mutations in the hemochromatosis gene (HFE), Parkinson's disease and parkinsonism.
Neuroscience letters 2003;348(2):117-9.
2003: Omer T Njajou; Jeanine J Houwing-Duistermaat; Richard H Osborne; Norbert Vaessen; Jeannette M Vergeer; Jan Heeringa; Huibert A P Pols; Albert Hofman; C.M. Duijn
A population-based study of the effect of the HFE C282Y and H63D mutations on iron metabolism.
European journal of human genetics : EJHG 2003;11(3):225-31.
2003: Omer T Njajou; Behrooz Alizadeh; C.M. Duijn
Genetic screening for common mutations: lessons from hereditary hemochromatosis.
European journal of epidemiology 2003;18(1):3-4.
2002: Omer T Njajou; Gerard de Jong; Bianca Berghuis; Norbert Vaessen; Pieter J L M Snijders; Jan P Goossens; John H P Wilson; Martijn H Breuning; Ben A Oostra; Peter Heutink; Lodewijk A Sandkuijl; C.M. Duijn
Dominant hemochromatosis due to N144H mutation of SLC11A3: clinical and biological characteristics.
Blood cells, molecules & diseases 2002;29(3):439-43.
2002: Omer T Njajou; Behrooz Alizadeh; Norbert Vaessen; Jeannette M Vergeer; Jeanine J Houwing-Duistermaat; Albert Hofman; Huibert A P Pols; C.M. Duijn
The role of hemochromatosis C282Y and H63D gene mutations in type 2 diabetes: findings from the Rotterdam Study and meta-analysis.
Diabetes care 2002;25(11):2112-3.
2002: Omer T Njajou; Monika Hollander; Peter J Koudstaal; Albert Hofman; Jacqueline C M Witteman; Monique Breteler; C.M. Duijn
Mutations in the hemochromatosis gene (HFE) and stroke.
Stroke; a journal of cerebral circulation 2002;33(10):2363-6.
2002: Omer T Njajou; Norbert Vaessen; Ben A Oostra; Peter Heutink; C.M. Duijn
The hemochromatosis N144H mutation of SLC11A3 gene in patients with type 2 diabetes.
Molecular genetics and metabolism 2002;75(3):290-1.
2001: Omer T Njajou; Norbert Vaessen; Marijke Joosse; B Berghuis; Jeroen W F van Dongen; Martijn H Breuning; Pieter J L M Snijders; W P Rutten; Lodewijk A Sandkuijl; Ben A Oostra; C.M. Duijn; Peter Heutink
A mutation in SLC11A3 is associated with autosomal dominant hemochromatosis.
Nature genetics 2001;28(3):213-4.