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Ivo Nnane

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Bart van Hartingsveldt; Alexa Piantone; Esther Bouman-Thio; Hugh M Davis; Matthew J Loza; Ivo P Nnane; Kevin J Petty
Safety, tolerability and pharmacokinetics of a human anti-interleukin-13 monoclonal antibody (CNTO 5825) in an ascending single-dose first-in-human study.
X Tao; H Piao; DJ Canney; Michael R Borenstein; Ivo P Nnane
Biotransformation of letrozole in rat liver microsomes: effects of gender and tamoxifen.
X Tao; Angela Brodie; Ivo P Nnane
The effect of tamoxifen on the pharmacokinetics of letrozole in female rats.

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2013: Bart van Hartingsveldt; Alexa Piantone; Esther Bouman-Thio; Hugh M Davis; Matthew J Loza; Ivo P Nnane; Kevin J Petty
Safety, tolerability and pharmacokinetics of a human anti-interleukin-13 monoclonal antibody (CNTO 5825) in an ascending single-dose first-in-human study.
British journal of clinical pharmacology 2013;75(5):1289-98.
2007: X Tao; H Piao; DJ Canney; Michael R Borenstein; Ivo P Nnane
Biotransformation of letrozole in rat liver microsomes: effects of gender and tamoxifen.
Journal of pharmaceutical and biomedical analysis 2007;43(3):1078-85.
2006: X Tao; Angela Brodie; Ivo P Nnane
The effect of tamoxifen on the pharmacokinetics of letrozole in female rats.
Biopharmaceutics & drug disposition 2006;27(7):335-44.
2005: Ivo P Nnane; Lyaquat A Damani
Determination of the sulphoxides and sulphones of three simple sulphides in rat urine: effects of phenobarbitone, beta-naphthoflavone and methimazole.
Biomedical chromatography : BMC 2005;19(1):87-98.
2004: Chunyu Wu; Vincent Njar; Angela Brodie; Michael R Borenstein; Ivo P Nnane
Quantification of a novel retinoic acid metabolism inhibitor, 4-(1H-imidazol-1-yl)retinoic acid (VN/14-1RA) and other retinoids in rat plasma by liquid chromatography with diode-array detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2004;810(2):203-8.
2004: Venkatesh D Handratta; Danijela Jelovac; Brian Long; Ritesh Kataria; Ivo P Nnane; Vincent Njar; Angela Brodie
Potent CYP17 inhibitors: improved syntheses, pharmacokinetics and anti-tumor activity in the LNCaP human prostate cancer model.
The Journal of steroid biochemistry and molecular biology 2004;92(3):155-65.
2004: Ivo P Nnane; PK Kadaba
Pharmacokinetic studies of a novel anticonvulsant, 2-(4-chlorophenyl)amino-2-(4-pyridyl)ethane, in rats.
Pharmacological research : the official journal of the Italian Pharmacological Society 2004;49(2):177-83.
2003: X Tao; PK Kadaba; Ivo P Nnane
Chiral liquid chromatography resolution and stereoselective pharmacokinetic study of the enantiomers of a novel anticonvulsant, N-(4-chlorophenyl)-1-(4-pyridyl)ethylamine, in rats.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2003;796(1):35-44.
2003: Ivo P Nnane; Lyaquat A Damani
Involvement of cytochrome P450 and the flavin-containing monooxygenase(s) in the sulphoxidation of simple sulphides in human liver microsomes.
Life sciences 2003;73(3):359-69.
2003: Ivo P Nnane; Vincent Njar; Angela Brodie
Pharmacokinetics of novel inhibitors of androgen synthesis after intravenous administration in mice.
Cancer chemotherapy and pharmacology 2003;51(6):519-24.
2003: Ivo P Nnane; Lyaquat A Damani
Sulphoxidation of ethyl methyl sulphide, 4-chlorophenyl methyl sulphide and diphenyl sulphide by purified pig liver flavin-containing monooxygenase.
Xenobiotica; the fate of foreign compounds in biological systems 2003;33(1):83-91.
2002: Ivo P Nnane; Lyaquat A Damani
HPLC analysis of 4-chlorophenyl methyl sulphide and diphenyl sulphide and their corresponding sulphoxides and sulphones in rat liver microsomes.
Journal of pharmaceutical and biomedical analysis 2002;27(1-2):315-25.
2001: Ivo P Nnane; Lyaquat A Damani
Pharmacokinetics of trimethylamine in rats, including the effects of a synthetic diet.
Xenobiotica; the fate of foreign compounds in biological systems 2001;31(10):749-55.
2001: Ivo P Nnane; Vincent Njar; Angela Brodie
Pharmacokinetic profile of 3beta-hydroxy-17-(1H-1,2,3-triazol-1-yl)androsta-5,16-diene (VN/87-1), a potent androgen synthesis inhibitor, in mice.
The Journal of steroid biochemistry and molecular biology 2001;78(3):241-6.
2000: Brian Long; Dmitry N Grigoryev; Ivo P Nnane; Y Liu; YZ Ling; Angela Brodie
Antiandrogenic effects of novel androgen synthesis inhibitors on hormone-dependent prostate cancer.
Cancer research 2000;60(23):6630-40.
2000: Vincent Njar; Ivo P Nnane; Angela Brodie
Potent inhibition of retinoic acid metabolism enzyme(s) by novel azolyl retinoids.
Bioorganic & medicinal chemistry letters 2000;10(17):1905-8.
2000: Ivo P Nnane; Brian Long; YZ Ling; Dmitry N Grigoryev; Angela Brodie
Anti-tumour effects and pharmacokinetic profile of 17-(5'-isoxazolyl)androsta-4,16-dien-3-one (L-39) in mice: an inhibitor of androgen synthesis.
British journal of cancer 2000;83(1):74-82.
1999: Ivo P Nnane; Vincent Njar; Y Liu; Qing Lu; Angela Brodie
Effects of novel 17-azolyl compounds on androgen synthesis in vitro and in vivo.
The Journal of steroid biochemistry and molecular biology 1999;71(3-4):145-52.
1999: Ivo P Nnane; Lyaquat A Damani
Metabolism of ethyl methyl sulphide and sulphoxide in rat microsomal fractions.
Xenobiotica; the fate of foreign compounds in biological systems 1999;29(11):1101-13.
1999: Dmitry N Grigoryev; Brian Long; Ivo P Nnane; Vincent Njar; Y Liu; Angela Brodie
Effects of new 17alpha-hydroxylase/C(17,20)-lyase inhibitors on LNCaP prostate cancer cell growth in vitro and in vivo.
British journal of cancer 1999;81(4):622-30.
1999: Ge Lin; Ivo P Nnane; T Y Cheng
The effects of pretreatment with glycyrrhizin and glycyrrhetinic acid on the retrorsine-induced hepatotoxicity in rats.
Toxicon : official journal of the International Society on Toxinology 1999;37(9):1259-70.
1999: Ivo P Nnane; K Kato; Y Liu; Brian Long; Qing Lu; X Wang; YZ Ling; Angela Brodie
Inhibition of androgen synthesis in human testicular and prostatic microsomes and in male rats by novel steroidal compounds.
Endocrinology 1999;140(6):2891-7.
1999: Ivo P Nnane; M C Tsai; Ge Lin; Lyaquat A Damani; M Mitterhauser; I Zolle
Pharmacokinetics of 2-methoxyphenylmetyrapone and 2-bromophenylmetyrapone in rats.
European journal of drug metabolism and pharmacokinetics 1999;24(1):23-9.
1998: Ge Lin; Ivo P Nnane; Lyaquat A Damani; K K Tse; A H Chow; PK Kadaba
High performance liquid chromatographic analysis of a novel aminoalkylpyridine anticonvulsant 2-(4-chlorophenyl)amino-2-(4-pyridyl)ethane.
Journal of pharmaceutical and biomedical analysis 1998;18(3):403-9.
1998: YZ Ling; J S Li; K Kato; Y Liu; X Wang; GT Klus; K Marat; Ivo P Nnane; Angela Brodie
Synthesis and in vitro activity of some epimeric 20 alpha-hydroxy, 20-oxime and aziridine pregnene derivatives as inhibitors of human 17 alpha-hydroxylase/C17,20-lyase and 5 alpha-reductase.
Bioorganic & medicinal chemistry 1998;6(10):1683-93.
1998: Ivo P Nnane; K Kato; Y Liu; Qing Lu; X Wang; YZ Ling; Angela Brodie
Effects of some novel inhibitors of C17,20-lyase and 5alpha-reductase in vitro and in vivo and their potential role in the treatment of prostate cancer.
Cancer research 1998;58(17):3826-32.
1998: Vincent Njar; K Kato; Ivo P Nnane; Dmitry N Grigoryev; Brian Long; Angela Brodie
Novel 17-azolyl steroids, potent inhibitors of human cytochrome 17 alpha-hydroxylase-C17,20-lyase (P450(17) alpha): potential agents for the treatment of prostate cancer.
Journal of medicinal chemistry 1998;41(6):902-12.
1996: Lyaquat A Damani; Ivo P Nnane
The assessment of flavin-containing monooxygenase activity in intact animals.
Drug metabolism and drug interactions 1996;13(1):1-28.