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Berthold Nock

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Panteleimon J Marsouvanidis; Jean Martinez; Céline M'Kadmi; Berthold A Nock; Linda van der Graaf; jean-alain fehrentz; Bouchra Hajjaj; Eric P Krenning; Theodosia Maina; Luc Brunel; Marion de Jong
Gastrin releasing peptide receptor-directed radioligands based on a bombesin antagonist: synthesis, (111)in-labeling, and preclinical profile.
Berthold A Nock; Jean Claude Reubi; Beatrice Waser; Renzo Cescato; Eleni Ketani; Theodosia Maina
[(99m)Tc]Demomedin C, a radioligand based on human gastrin releasing peptide(18-27): synthesis and preclinical evaluation in gastrin releasing peptide receptor-expressing models.
Frantisek Trejtnar; Milan Laznicek; Alice Laznickova; Theodosia Maina; Berthold A Nock; Zbynek Novy; Martin Behe
Distribution, elimination, and renal handling of (99m)technetium-Demogastrin 1.

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All Publications

2013: Panteleimon J Marsouvanidis; Jean Martinez; Céline M'Kadmi; Berthold A Nock; Linda van der Graaf; jean-alain fehrentz; Bouchra Hajjaj; Eric P Krenning; Theodosia Maina; Luc Brunel; Marion de Jong
Gastrin releasing peptide receptor-directed radioligands based on a bombesin antagonist: synthesis, (111)in-labeling, and preclinical profile.
Journal of medicinal chemistry 2013;56(6):2374-84.
2012: Berthold A Nock; Jean Claude Reubi; Beatrice Waser; Renzo Cescato; Eleni Ketani; Theodosia Maina
[(99m)Tc]Demomedin C, a radioligand based on human gastrin releasing peptide(18-27): synthesis and preclinical evaluation in gastrin releasing peptide receptor-expressing models.
Journal of medicinal chemistry 2012;55(19):8364-74.
2012: Frantisek Trejtnar; Milan Laznicek; Alice Laznickova; Theodosia Maina; Berthold A Nock; Zbynek Novy; Martin Behe
Distribution, elimination, and renal handling of (99m)technetium-Demogastrin 1.
Cancer biotherapy & radiopharmaceuticals 2012;27(2):169-74.
2012: Aikaterini Tatsi; Beatrice Waser; Jean Claude Reubi; Renzo Cescato; Paul Cordopatis; Marion de Jong; Eric P Krenning; Theodosia Maina; Berthold A Nock
[111In-DOTA]Somatostatin-14 analogs as potential pansomatostatin-like radiotracers - first results of a preclinical study.
EJNMMI research 2012;2(1):25.
2011: Meltem Ocak; Petra Kolenc Peitl; C Rangger; Jean Claude Reubi; Jane K Sosabowski; Annemarie Eek; Anna Helbok; Giancarlo Morelli; Berthold A Nock; Wouter A P Breeman; Clemens Decristoforo
Comparison of biological stability and metabolism of CCK2 receptor targeting peptides, a collaborative project under COST BM0607.
European journal of nuclear medicine and molecular imaging 2011;38(8):1426-35.
2011: Gil Fridkin; Theodosia Maina; Berthold A Nock; Dan Blat; Vered Lev-Goldman; Yosef Scolnik; Aviva Kapitkovski; Yelena Vachutinsky; Yoram Shechter; Yaakov Levy
Intramolecular azo-bridge as a cystine disulfide bond surrogate: Somatostatin-14 and brain natriuretic peptide (BNP) analogs.
Bioorganic & medicinal chemistry 2011;19(2):798-806.
2009: Alida C Fröberg; Marion De Jong; Berthold A Nock; Wouter A P Breeman; Jack Erion; Theodosia Maina; Marion Verdijsseldonck; Wouter W de Herder; Aad van Der Lugt; Peter P M Kooij; Eric P Krenning
Comparison of three radiolabelled peptide analogues for CCK-2 receptor scintigraphy in medullary thyroid carcinoma.
European journal of nuclear medicine and molecular imaging 2009;36(8):1265-72.
2008: CHRISTOS PETROU; Vassiliki Magafa; Anastasia Nikolopoulou; George Pairas; Berthold A Nock; Theodosia Maina; Paul Cordopatis
Synthesis and sst(2) binding profiles of new [Tyr(3)]octreotate analogs.
Journal of peptide science : an official publication of the European Peptide Society 2008;14(6):725-30.
2007: Theodosia Maina; Anastasia Nikolopoulou; Eleni Stathopoulou; Athanassios S Galanis; Paul Cordopatis; Berthold A Nock
[99mTc]Demotensin 5 and 6 in the NTS1-R-targeted imaging of tumours: synthesis and preclinical results.
European journal of nuclear medicine and molecular imaging 2007;34(11):1804-14.
2007: Frantisek Trejtnar; Milan Laznicek; Alice Laznickova; Martin Kopecky; Milos Petrik; Martin Béhé; Jörg Schmidt; Helmut R Maecke; Theodosia Maina; Berthold A Nock
Biodistribution and elimination characteristics of two 111In-labeled CCK-2/gastrin receptor-specific peptides in rats.
Anticancer research 2007;27(2):907-12.
2006: Berthold A Nock; Anastasia Nikolopoulou; Jean Claude Reubi; Veronique Maes; Peter Conrath; Dirk Tourwé; Theodosia Maina
Toward stable N4-modified neurotensins for NTS1-receptor-targeted tumor imaging with 99mTc.
Journal of medicinal chemistry 2006;49(15):4767-76.
2006: Theodosia Maina; Berthold A Nock; Paul Cordopatis; Bert F Bernard; Wouter A P Breeman; Arthur van Gameren; Ria van den Berg; Jean Claude Reubi; Eric P Krenning; Marion De Jong
[(99m)Tc]Demotate 2 in the detection of sst(2)-positive tumours: a preclinical comparison with [(111)In]DOTA-tate.
European journal of nuclear medicine and molecular imaging 2006;33(7):831-40.
2006: Anastasia Nikolopoulou; Theodosia Maina; Petros Sotiriou; Paul Cordopatis; Berthold A Nock
Tetraamine-modified octreotide and octreotate: labeling with 99mTc and preclinical comparison in AR4-2J cells and AR4-2J tumor-bearing mice.
Journal of peptide science : an official publication of the European Peptide Society 2006;12(2):124-31.
2006: Theodosia Maina; Berthold A Nock; Stephen Mather
Targeting prostate cancer with radiolabelled bombesins.
Cancer imaging : the official publication of the International Cancer Imaging Society 2006;6():153-7.
2006: Anastasia Nikolopoulou; Berthold A Nock; Theodosia Maina
99mTc targeting of Sst2-expressing tumors by tetraamineoctreotide: first results in CA20948 cells and rat models.
Anticancer research 2006;26(1A):363-6.
2005: Aikaterini A Zompra; Vassiliki Magafa; Fotini N Lamari; Anastasia Nikolopoulou; Berthold A Nock; Theodosia Maina; Georgios A A. Spyroulias; Nikos Karamanos; Paul Cordopatis
GnRH analogues containing conformationally restricted amino acids in positions 3 and 6: differential impact on pituitary binding affinity and direct antiproliferative effect on breast cancer cells.
The journal of peptide research : official journal of the American Peptide Society 2005;66 Suppl 1():57-64.
2005: Buck E Rogers; Jesse J Parry; Rebecca Andrews; Paul Cordopatis; Berthold A Nock; Theodosia Maina
MicroPET imaging of gene transfer with a somatostatin receptor-based reporter gene and (94m)Tc-Demotate 1.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2005;46(11):1889-97.
2005: Berthold A Nock; Theodosia Maina; Martin Béhé; Anastasia Nikolopoulou; Martin Gotthardt; Jörg S Schmitt; Thomas M Behr; Helmut R Mäcke
CCK-2/gastrin receptor-targeted tumor imaging with (99m)Tc-labeled minigastrin analogs.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2005;46(10):1727-36.
2005: Georgios A A. Spyroulias; Athanassios S Galanis; CHRISTOS PETROU; D Vahliotis; Petros Sotiriou; Anastasia Nikolopoulou; Berthold A Nock; Theodosia Maina; Paul Cordopatis
3D solution structure of [Tyr3]octreotate derivatives in DMSO: structure differentiation of peptide core due to chelate group attachment and biologically active conformation.
Medicinal chemistry (Shāriqah (United Arab Emirates)) 2005;1(5):487-99.
2005: Martin Kopecky; Frantisek Trejtnar; Milan Laznicek; Alice Laznickova; Vladimir Semecky; Theodosia Maina; Berthold A Nock
99mTc demotate 1: biodistribution and elimination characteristics in rats.
Nuclear medicine communications 2005;26(6):549-54.
2005: Theodosia Maina; Berthold A Nock; Hanwen Zhang; Anastasia Nikolopoulou; Beatrice Waser; Jean Claude Reubi; Helmut R Maecke
Species differences of bombesin analog interactions with GRP-R define the choice of animal models in the development of GRP-R-targeting drugs.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2005;46(5):823-30.
2005: Berthold A Nock; Anastasia Nikolopoulou; Athanassios S Galanis; Paul Cordopatis; Beatrice Waser; Jean Claude Reubi; Theodosia Maina
Potent bombesin-like peptides for GRP-receptor targeting of tumors with 99mTc: a preclinical study.
Journal of medicinal chemistry 2005;48(1):100-10.
2004: Michael Gabriel; Clemens Decristoforo; Theodosia Maina; Berthold A Nock; Elisabeth vonGuggenberg; Paul Cordopatis; Roy Moncayo
99mTc-N4-[Tyr3]Octreotate Versus 99mTc-EDDA/HYNIC-[Tyr3]Octreotide: an intrapatient comparison of two novel Technetium-99m labeled tracers for somatostatin receptor scintigraphy.
Cancer biotherapy & radiopharmaceuticals 2004;19(1):73-9.
2003: Clemens Decristoforo; Theodosia Maina; Berthold A Nock; Michael Gabriel; Paul Cordopatis; Roy Moncayo
99mTc-Demotate 1: first data in tumour patients-results of a pilot/phase I study.
European journal of nuclear medicine and molecular imaging 2003;30(9):1211-9.
2003: Tino Schurrat; Heiko Alfke; Martin Béhé; Theodosia Maina; Berthold A Nock; Helmut R Mäcke; Johannes T Heverhagen; Klaus Jochen Klose; Horst Halling; Thomas M Behr; Nils Schramm
Molecular gastrin receptor localisation in mice using high-resolution SPET-MRI image fusion.
European journal of nuclear medicine and molecular imaging 2003;30(5):800.
2003: Berthold A Nock; Anastasia Nikolopoulou; Efstratios Chiotellis; George Loudos; Dimitrios Maintas; Jean Claude Reubi; Theodosia Maina
[99mTc]Demobesin 1, a novel potent bombesin analogue for GRP receptor-targeted tumour imaging.
European journal of nuclear medicine and molecular imaging 2003;30(2):247-58.
2002: Theodosia Maina; Berthold A Nock; Anastasia Nikolopoulou; Petros Sotiriou; George Loudos; Dimitrios Maintas; Paul Cordopatis; Efstratios Chiotellis
[99mTc]Demotate, a new 99mTc-based [Tyr3]octreotate analogue for the detection of somatostatin receptor-positive tumours: synthesis and preclinical results.
European journal of nuclear medicine and molecular imaging 2002;29(6):742-53.
2001: Minas Papadopoulos; Berthold A Nock; Theodosia Maina; Ioannis Pirmettis; Catherine P Raptopoulou; Anastasios J Tasiopoulos; A Troganis; Themistoklis A Kabanos; Aris Terzis; Efstratios Chiotellis
Novel lipophilic amidate oxorhenium and oxotechnetium complexes as potential brain agents: synthesis, characterization and biological evaluation.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2001;6(2):159-65.
2000: Berthold A Nock; Theodosia Maina; F Tisato; Catherine P Raptopoulou; Aris Terzis; Efstratios Chiotellis
Oxorhenium phosphinophenolato complexes with model peptide fragments: synthesis, characterization, and stability considerations.
Inorganic chemistry 2000;39(23):5197-202.
2000: Berthold A Nock; Theodosia Maina; F Tisato; Minas Papadopoulos; Catherine P Raptopoulou; Aris Terzis; Efstratios Chiotellis
Synthesis and characterization of six-coordinate "3 + 2" mixed-ligand oxorhenium complexes with the o-diphenylphosphinophenolato ligand and tridentate coligands of different N and S donor atom combinations.
Inorganic chemistry 2000;39(10):2178-84.
1999: Charalambos Tsoukalas; Minas S Papadopoulos; Theodosia Maina; Ioannis Pirmettis; Berthold A Nock; Catherine P Raptopoulou; Aris Terzis; Efstratios Chiotellis
Characterization and preliminary evaluation of ester-modified technetium-99m SNS/S mixed ligand complexes as potential brain perfusion agents.
Nuclear medicine and biology 1999;26(3):297-304.
1999: Berthold A Nock; Theodosia Maina; Drakoulis Yannoukakos; Ioannis Pirmettis; Minas S Papadopoulos; Efstratios Chiotellis
Glutathione-mediated metabolism of technetium-99m SNS/S mixed ligand complexes: a proposed mechanism of brain retention.
Journal of medicinal chemistry 1999;42(6):1066-75.