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Constance Tom Noguchi

Research Profile

Chemicals & Drugs

Disorders

Anemia, Sickle Cell

Living Beings

Physiology

Anatomy

Concepts & Ideas

Molecular Sequence Data

Procedures

Reverse Transcriptase Polymerase Chain Reaction

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Publications

TOP 3
Heather Rogers; Li Wang; Babette Weksler; Xiaobing Yu; Keji Zhao; Mawadda Alnaeeli; James J Bieker; Kairong Cui; Suming Huang; josef prchal; Constance Tom Noguchi
T-cell acute leukemia 1 (TAL1) regulation of erythropoietin receptor and association with excessive erythrocytosis.
Li Wang; Yun-Ping Wu; Suming Huang; Yi Jia; Heather Rogers; Constance Tom Noguchi
GATA-binding protein 4 (GATA-4) and T-cell acute leukemia 1 (TAL1) regulate myogenic differentiation and erythropoietin response via cross-talk with Sirtuin1 (Sirt1).
Yi Jia; Norio Suzuki; Masayuki Yamamoto; Max Gassmann; Constance Tom Noguchi
Endogenous erythropoietin signaling facilitates skeletal muscle repair and recovery following pharmacologically induced damage.

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2012: Heather Rogers; Li Wang; Babette Weksler; Xiaobing Yu; Keji Zhao; Mawadda Alnaeeli; James J Bieker; Kairong Cui; Suming Huang; josef prchal; Constance Tom Noguchi
T-cell acute leukemia 1 (TAL1) regulation of erythropoietin receptor and association with excessive erythrocytosis.
The Journal of biological chemistry 2012;287(44):36720-31.
2012: Li Wang; Yun-Ping Wu; Suming Huang; Yi Jia; Heather Rogers; Constance Tom Noguchi
GATA-binding protein 4 (GATA-4) and T-cell acute leukemia 1 (TAL1) regulate myogenic differentiation and erythropoietin response via cross-talk with Sirtuin1 (Sirt1).
The Journal of biological chemistry 2012;287(36):30157-69.
2012: Yi Jia; Norio Suzuki; Masayuki Yamamoto; Max Gassmann; Constance Tom Noguchi
Endogenous erythropoietin signaling facilitates skeletal muscle repair and recovery following pharmacologically induced damage.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012;26(7):2847-58.
2012: Mawadda Alnaeeli; Xiaoxia Li; Barbora Piknova; Heather Rogers; Li Wang; Constance Tom Noguchi
Erythropoietin in brain development and beyond.
Anatomy research international 2012;2012():953264.
2011: Ruifeng Teng; John W Calvert; Nathawut Sibmooh; Barbora Piknova; Norio Suzuki; Junhui Sun; Kevin Martinez; Masayuki Yamamoto; Alan N Schechter; David J Lefer; Constance Tom Noguchi
Acute erythropoietin cardioprotection is mediated by endothelial response.
Basic research in cardiology 2011;106(3):343-54.
2011: Ruifeng Teng; Masayuki Yamamoto; Dena R Yver; Daniel Schimel; Norio Suzuki; Tatyana Chanturiya; Samuel W Cushman; Oksana Gavrilova; Lewis Hsu; Lynne Hugendubler; Selin Mammen; Elisabetta Mueller; Constance Tom Noguchi
Disrupted erythropoietin signalling promotes obesity and alters hypothalamus proopiomelanocortin production.
Nature communications 2011;2():520.
2010: Zhi-Yong Chen; Li Wang; Pundit Asavaritkrai; Constance Tom Noguchi
Up-regulation of erythropoietin receptor by nitric oxide mediates hypoxia preconditioning.
Journal of neuroscience research 2010;88(14):3180-8.
2009: Vladan P Cokić; Bojana B Beleslin-Cokić; Reginald D Smith; Antaeus P Economou; Larry M Wahl; Constance Tom Noguchi; Alan N Schechter
Stimulated stromal cells induce gamma-globin gene expression in erythroid cells via nitric oxide production.
Experimental hematology 2009;37(10):1230-7.
2009: Yi Jia; Renaud Warin; Xiaobing Yu; Reed Epstein; Constance Tom Noguchi
Erythropoietin signaling promotes transplanted progenitor cell survival.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(9):3089-99.
2008: Constance Tom Noguchi
Where the Epo cells are.
Blood 2008;111(10):4836-7.
2008: Vladan P Cokic; Silvana A Andric; Stanko S Stojilkovic; Constance Tom Noguchi; Alan N Schechter
Hydroxyurea nitrosylates and activates soluble guanylyl cyclase in human erythroid cells.
Blood 2008;111(3):1117-23.
2008: Constance Tom Noguchi; Li Wang; Heather M Rogers; Ruifeng Teng; Yi Jia
Survival and proliferative roles of erythropoietin beyond the erythroid lineage.
Expert reviews in molecular medicine 2008;10():e36.
2008: Heather Rogers; Xiaobing Yu; Jie Wen; Reginald Smith; Eitan Fibach; Constance Tom Noguchi
Hypoxia alters progression of the erythroid program.
Experimental hematology 2008;36(1):17-27.
2007: Lei Wang; Zheng Gang Zhang; Sara R Gregg; Rui Lan Zhang; Zhongxian Jiao; Yvonne LeTourneau; Xianshuang Liu; Yifan Feng; Jens Gerwien; Lars Torup; Marcel Leist; Constance Tom Noguchi; Zhi-Yong Chen; Michael Chopp
The Sonic hedgehog pathway mediates carbamylated erythropoietin-enhanced proliferation and differentiation of adult neural progenitor cells.
The Journal of biological chemistry 2007;282(44):32462-70.
2007: Constance Tom Noguchi; Pundit Asavaritikrai; Ruifeng Teng; Yi Jia
Role of erythropoietin in the brain.
Critical reviews in oncology/hematology 2007;64(2):159-71.
2007: Zhi-Yong Chen; Pundit Asavaritikrai; Josef T Prchal; Constance Tom Noguchi
Endogenous erythropoietin signaling is required for normal neural progenitor cell proliferation.
The Journal of biological chemistry 2007;282(35):25875-83.
2007: Tong-Jian Shen; Heather Rogers; Xiaobing Yu; Felix Lin; Constance Tom Noguchi; Chien Ho
Modification of globin gene expression by RNA targeting strategies.
Experimental hematology 2007;35(8):1209-18.
2007: Vladan P Cokic; Bojana B Beleslin-Cokic; Constance Tom Noguchi; Alan N Schechter
Hydroxyurea increases eNOS protein levels through inhibition of proteasome activity.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2007;16(3):371-8.
2006: Vladan P Cokic; Bojana B Beleslin-Cokic; Melanija Tomic; Stanko S Stojilkovic; Constance Tom Noguchi; Alan N Schechter
Hydroxyurea induces the eNOS-cGMP pathway in endothelial cells.
Blood 2006;108(1):184-91.
2006: Lewis Hsu; Bhalchandra Diwan; Jerrold M Ward; Constance Tom Noguchi
Pathology of "Berkeley" sickle-cell mice includes gallstones and priapism.
Blood 2006;107(8):3414-5.
2006: Zhi-Yong Chen; Renaud Warin; Constance Tom Noguchi
Erythropoietin and normal brain development: receptor expression determines multi-tissue response.
Neuro-degenerative diseases 2006;3(1-2):68-75.
2005: Jie Wen; Suming Huang; Heather Rogers; Liliane A Dickinson; Terumi Kohwi-Shigematsu; Constance Tom Noguchi
SATB1 family protein expressed during early erythroid differentiation modifies globin gene expression.
Blood 2005;105(8):3330-9.
2005: Jie Wen; Suming Huang; Svetlana D Pack; Xiaobing Yu; Stephen J Brandt; Constance Tom Noguchi
Tal1/SCL binding to pericentromeric DNA represses transcription.
The Journal of biological chemistry 2005;280(13):12956-66.
2004: Bojana B Beleslin-Cokic; Vladan P Cokic; Xiaobing Yu; Babette B Weksler; Alan N Schechter; Constance Tom Noguchi
Erythropoietin and hypoxia stimulate erythropoietin receptor and nitric oxide production by endothelial cells.
Blood 2004;104(7):2073-80.
2004: David F Stroncek; Karen M Byrne; Constance Tom Noguchi; Alan N Schechter; Susan F Leitman
Increasing hemoglobin oxygen saturation levels in sickle trait donor whole blood prevents hemoglobin S polymerization and allows effective white blood cell reduction by filtration.
Transfusion 2004;44(9):1293-9.
2002: David F Stroncek; Tobie Rainer; Victoria Sharon; Karen M Byrne; Constance Tom Noguchi; HARVEY KLEIN; Alan N Schechter; Susan F Leitman
Sickle Hb polymerization in RBC components from donors with sickle cell trait prevents effective WBC reduction by filtration.
Transfusion 2002;42(11):1466-72.
2002: Xiuli Xu; Virginia L Lockamy; Kejing Chen; Zhi Huang; Howard Shields; S Bruce King; Samir K Ballas; James S Nichols; Mark T Gladwin; Constance Tom Noguchi; Alan N Schechter; Daniel B Kim-Shapiro
Effects of iron nitrosylation on sickle cell hemoglobin solubility.
The Journal of biological chemistry 2002;277(39):36787-92.
2002: Xiaobing Yu; John J Shacka; Jeffrey B Eells; Carlos Suarez-Quian; Ronald Przygodzki; Bojana B Beleslin-Cokic; Chyuan-Sheng Lin; Vera M Nikodem; Barbara L Hempstead; Kathleen C Flanders; Frank Costantini; Constance Tom Noguchi
Erythropoietin receptor signalling is required for normal brain development.
Development (Cambridge, England) 2002;129(2):505-16.
2001: Constance Tom Noguchi; Mark T Gladwin; B Diwan; P Merciris; R Smith; Xiaobing Yu; Gregory S Buzard; Anthony L Fitzhugh; Larry K Keefer; Alan N Schechter; N Mohandas
Pathophysiology of a sickle cell trait mouse model: human alpha(beta)(S) transgenes with one mouse beta-globin allele.
Blood cells, molecules & diseases 2001;27(6):971-7.
2001: Mark T Gladwin; Frederick P Ognibene; James H Shelhamer; Margaret E Pease-Fye; Constance Tom Noguchi; Griffin P Rodgers; Alan N Schechter
Nitric oxide transport on sickle cell hemoglobin: where does it bind?
Free radical research 2001;35(2):175-80.
2001: Xiaobing Yu; C S Lin; F Costantini; Constance Tom Noguchi
The human erythropoietin receptor gene rescues erythropoiesis and developmental defects in the erythropoietin receptor null mouse.
Blood 2001;98(2):475-7.
2001: Laura Elnitski; J Li; Constance Tom Noguchi; Webb Miller; Ross C Hardison
A negative cis-element regulates the level of enhancement by hypersensitive site 2 of the beta-globin locus control region.
The Journal of biological chemistry 2001;276(9):6289-98.
2000: Pranvera Ikonomi; Constance Tom Noguchi; W Miller; H Kassahun; Ross C Hardison; Alan N Schechter
Levels of GATA-1/GATA-2 transcription factors modulate expression of embryonic and fetal hemoglobins.
Gene 2000;261(2):277-87.
2000: M Ogilvie; Xiaobing Yu; V Nicolas-Metral; S M Pulido; C Liu; Urs T Ruegg; Constance Tom Noguchi
Erythropoietin stimulates proliferation and interferes with differentiation of myoblasts.
The Journal of biological chemistry 2000;275(50):39754-61.
2000: Pranvera Ikonomi; C E Rivera; M Riordan; G Washington; Alan N Schechter; Constance Tom Noguchi
Overexpression of GATA-2 inhibits erythroid and promotes megakaryocyte differentiation.
Experimental hematology 2000;28(12):1423-31.
2000: K Chin; Xiaobing Yu; Bojana B Beleslin-Cokic; C Liu; K Shen; Harvey W Mohrenweiser; Constance Tom Noguchi
Production and processing of erythropoietin receptor transcripts in brain.
Brain research. Molecular brain research 2000;81(1-2):29-42.
2000: Reginald D Smith; J Li; Constance Tom Noguchi; Alan N Schechter
Quantitative PCR analysis of HbF inducers in primary human adult erythroid cells.
Blood 2000;95(3):863-9.
1999: Chris P Miller; Z Y Liu; Constance Tom Noguchi; Don M Wojchowski
A minimal cytoplasmic subdomain of the erythropoietin receptor mediates erythroid and megakaryocytic cell development.
Blood 1999;94(10):3381-7.
1999: Tong-Jian Shen; Pranvera Ikonomi; R Smith; Constance Tom Noguchi; Chien Ho
Multi-ribozyme targeting of human alpha-globin gene expression.
Blood cells, molecules & diseases 1999;25(5-6):361-73.
1999: Mark T Gladwin; Alan N Schechter; James H Shelhamer; Lewis K Pannell; D A Conway; BW Hrinczenko; James S Nichols; Margaret E Pease-Fye; Constance Tom Noguchi; Griffin P Rodgers; Frederick P Ognibene
Inhaled nitric oxide augments nitric oxide transport on sickle cell hemoglobin without affecting oxygen affinity.
The Journal of clinical investigation 1999;104(7):937-45.
1998: J Li; Constance Tom Noguchi; W Miller; Ross C Hardison; Alan N Schechter
Multiple regulatory elements in the 5'-flanking sequence of the human epsilon-globin gene.
The Journal of biological chemistry 1998;273(17):10202-9.
1998: S Hasegawa; Griffin P Rodgers; Nancy K Dwyer; Constance Tom Noguchi; E Joan Blanchette-Mackie; N Uyesaka; Alan N Schechter; Eitan Fibach
Sickling of nucleated erythroid precursors from patients with sickle cell anemia.
Experimental hematology 1998;26(4):314-9.
1997: C Liu; K Shen; Z Liu; Constance Tom Noguchi
Regulated human erythropoietin receptor expression in mouse brain.
The Journal of biological chemistry 1997;272(51):32395-400.
1996: C Liu; K Yu; K Shen; Z Liu; Constance Tom Noguchi
Transgenic mice containing the human erythropoietin receptor gene exhibit correct hematopoietic and neural expression.
Proceedings of the Association of American Physicians 1996;108(6):449-54.
1995: S Hasegawa; H Hiruma; Nobuhiro Uyesaka; Constance Tom Noguchi; Alan N Schechter; Griffin P Rodgers
Filterability of mixtures of sickle and normal erythrocytes.
American journal of hematology 1995;50(2):91-7.
1995: K Chin; N Oda; K Shen; Constance Tom Noguchi
Regulation of transcription of the human erythropoietin receptor gene by proteins binding to GATA-1 and Sp1 motifs.
Nucleic acids research 1995;23(15):3041-9.
1995: H Hiruma; Constance Tom Noguchi; Nobuhiro Uyesaka; Alan N Schechter; Griffin P Rodgers
Contributions of sickle hemoglobin polymer and sickle cell membranes to impaired filterability.
The American journal of physiology 1995;268(5 Pt 2):H2003-8.
1995: H Hiruma; Constance Tom Noguchi; Nobuhiro Uyesaka; S Hasegawa; E J Blanchette-Mackie; Alan N Schechter; Griffin P Rodgers
Sickle cell rheology is determined by polymer fraction--not cell morphology.
American journal of hematology 1995;48(1):19-28.
1994: Z Y Liu; K Chin; Constance Tom Noguchi
Tissue specific expression of human erythropoietin receptor in transgenic mice.
Developmental biology 1994;166(1):159-69.
1993: Constance Tom Noguchi; Alan N Schechter; Griffin P Rodgers
Sickle cell disease pathophysiology.
Baillière's clinical haematology 1993;6(1):57-91.
1993: B Peters; N Merezhinskaya; J F Diffley; Constance Tom Noguchi
Protein-DNA interactions in the epsilon-globin gene silencer.
The Journal of biological chemistry 1993;268(5):3430-7.
1993: Griffin P Rodgers; George J Dover; Nobuhiro Uyesaka; Constance Tom Noguchi; Alan N Schechter; A W Nienhuis
Augmentation by erythropoietin of the fetal-hemoglobin response to hydroxyurea in sickle cell disease.
The New England journal of medicine 1993;328(2):73-80.
1992: Yuko Wada-Kiyama; B Peters; Constance Tom Noguchi
The epsilon-globin gene silencer. Characterization by in vitro transcription.
The Journal of biological chemistry 1992;267(16):11532-8.
1991: Constance Tom Noguchi; K S Bae; K Chin; Y Wada; Alan N Schechter; William David Hankins
Cloning of the human erythropoietin receptor gene.
Blood 1991;78(10):2548-56.
1991: Y J Wu; Constance Tom Noguchi
Activation of globin gene expression by cDNAs from induced K562 cells. Evidence for involvement of ferritin in globin gene expression.
The Journal of biological chemistry 1991;266(26):17566-72.
1991: Constance Tom Noguchi; N Mohandas; J Blanchette-Mackie; S Mackie; E Raik; S Charache
Hemoglobin aggregation and pseudosickling in vitro of hemoglobin Setif-containing erythrocytes.
American journal of hematology 1991;36(2):131-9.
1990: Griffin P Rodgers; George J Dover; Constance Tom Noguchi; Alan N Schechter; A W Nienhuis
Hematologic responses of patients with sickle cell disease to treatment with hydroxyurea.
The New England journal of medicine 1990;322(15):1037-45.
1990: Griffin P Rodgers; Alan N Schechter; Constance Tom Noguchi; HARVEY KLEIN; A W Nienhuis; Robert F Bonner
Microcirculatory adaptations in sickle cell anemia: reactive hyperemia response.
The American journal of physiology 1990;258(1 Pt 2):H113-20.
1989: Y Wada; Constance Tom Noguchi
In vitro transcription with K562 cell nuclear extract and globin genes.
Progress in clinical and biological research 1989;316A():301-11.
1989: Griffin P Rodgers; Constance Tom Noguchi; Alan N Schechter
Hemodynamic studies in sickle cell disease.
Annals of the New York Academy of Sciences 1989;565():338-46.
1989: Y J Wu; Constance Tom Noguchi
Cloning of cDNA from induced K562 cells which can activate globin gene expression.
Progress in clinical and biological research 1989;316A():313-21.
1989: Griffin P Rodgers; George J Dover; Constance Tom Noguchi; Alan N Schechter; A W Nienhuis
Induction of fetal hemoglobin in sickle cell patients by hydroxyurea: the N.I.H. experience.
Progress in clinical and biological research 1989;316B():281-93.
1989: Constance Tom Noguchi; Griffin P Rodgers; Alan N Schechter
Intracellular polymerization. Disease severity and therapeutic predictions.
Annals of the New York Academy of Sciences 1989;565():75-82.
1988: Y Wada; Constance Tom Noguchi
In vitro differential expression of human globin genes.
The Journal of biological chemistry 1988;263(24):12142-6.
1988: Griffin P Rodgers; M S Roy; Constance Tom Noguchi; Alan N Schechter
Is there a role for selective vasodilation in the management of sickle cell disease?
Blood 1988;71(3):597-602.
1988: Constance Tom Noguchi; Griffin P Rodgers; G Serjeant; Alan N Schechter
Levels of fetal hemoglobin necessary for treatment of sickle cell disease.
The New England journal of medicine 1988;318(2):96-9.
1988: Griffin P Rodgers; M S Roy; Constance Tom Noguchi; Alan N Schechter
Use of selective vasodilation in treatment of sickle cell disease.
The American journal of pediatric hematology/oncology 1988;10(4):351-6.
1987: Constance Tom Noguchi; Griffin P Rodgers; G Serjeant; Alan N Schechter
Predicting therapeutic efficacy for sickle cell anemia.
Progress in clinical and biological research 1987;251():497-505.