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Cristina Nogueira

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Simone Pinton; Rita M Ramalho; Cecília M P Rodrigues; Marcel H M Sari; Ana Cristina Souza; Cristina W Nogueira
p,p'-Methoxyl-diphenyl diselenide protects against amyloid-β induced cytotoxicity in vitro and improves memory deficits in vivo.
Cristiani F Bortolatto; Pietro M Chagas; Cristiano R Jesse; Ethel A Wilhelm; Cristina W Nogueira
Organoselenium bis selenide attenuates 3-nitropropionic acid-induced neurotoxicity in rats.
Glaubia Sartori; Davi F Back; José S S Neto; Cristina W Nogueira; Ana Paula Pesarico; Gilson Zeni
Bis-vinyl selenides obtained via iron(III) catalyzed addition of PhSeSePh to alkynes: synthesis and antinociceptive activity.

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2013: Simone Pinton; Rita M Ramalho; Cecília M P Rodrigues; Marcel H M Sari; Ana Cristina Souza; Cristina W Nogueira
p,p'-Methoxyl-diphenyl diselenide protects against amyloid-β induced cytotoxicity in vitro and improves memory deficits in vivo.
Behavioural brain research 2013;247():241-7.
2013: Cristiani F Bortolatto; Pietro M Chagas; Cristiano R Jesse; Ethel A Wilhelm; Cristina W Nogueira
Organoselenium bis selenide attenuates 3-nitropropionic acid-induced neurotoxicity in rats.
Neurotoxicity research 2013;23(3):214-24.
2013: Glaubia Sartori; Davi F Back; José S S Neto; Cristina W Nogueira; Ana Paula Pesarico; Gilson Zeni
Bis-vinyl selenides obtained via iron(III) catalyzed addition of PhSeSePh to alkynes: synthesis and antinociceptive activity.
Organic & biomolecular chemistry 2013;11(7):1199-208.
2013: Marina Prigol; Gilson Zeni; Maria Rosário Bronze; Cristina W Nogueira; Luís Constantino
Physicochemical and biochemical profiling of diphenyl diselenide.
Applied biochemistry and biotechnology 2013;169(3):885-93.
2013: Pietro M Chagas; Juliano A Roehrs; Ethel A Wilhelm; Cristiani F Bortolatto; Cristina W Nogueira
Bis(phenylimidazoselenazolyl) diselenide: a compound with antinociceptive properties in mice.
Behavioural pharmacology 2013;24(1):37-44.
2012: Marina Prigol; Gilson Zeni; Maria Rosário Bronze; Cristina W Nogueira; Luís Constantino
In vitro metabolism of diphenyl diselenide in rat liver fractions. Conjugation with GSH and binding to thiol groups.
Chemico-biological interactions 2012;200(2-3):65-72.
2012: Mohammad Ibrahim; Anna M Deobald; Daiane Francine Meinerz; Cristina W Nogueira; Nilda B V Barbosa; Maricilia S Costa; Matheus Dos Santos; Waseem Hassan; Claudia V Klimaczewski; Joao B T Rocha
Antioxidant properties of diorganoyl diselenides and ditellurides: modulation by organic aryl or naphthyl moiety.
Molecular and cellular biochemistry 2012;371(1-2):97-104.
2012: Marina Prigol; César Augusto Brüning; Franciele Martini; Cristina W Nogueira
Comparative excretion and tissue distribution of selenium in mice and rats following treatment with diphenyl diselenide.
Biological trace element research 2012;150(1-3):272-7.
2012: César A Brüning; Marta M M F Duarte; Cristiano R Jesse; Cristiane Luchese; Marina Prigol; Silvane S Roman; Cristina W Nogueira
Protective effect of diphenyl diselenide on ischemia and reperfusion-induced cerebral injury: involvement of oxidative stress and pro-inflammatory cytokines.
Neurochemical research 2012;37(10):2249-58.
2012: Cristiane Luchese; Marta M M F Duarte; Marina Prigol; Cristina W Nogueira
Diphenyl diselenide reduces inflammation in the mouse model of pleurisy induced by carrageenan: reduction of pro-inflammatory markers and reactive species levels.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2012;61(10):1117-24.
2012: Cristiane Luchese; Carmine I Acker; Ricardo Brandão; Cristina W Nogueira
2,2'-dipyridyl diselenide is a better antioxidant than other disubstituted diaryl diselenides.
Molecular and cellular biochemistry 2012;367(1-2):153-63.
2012: Cristiani F Bortolatto; Cristiano R Jesse; Ethel A Wilhelm; Cristina W Nogueira
Selective blockade of A(2A) receptor protects against neurotoxicity induced by kainic acid in young rats.
Fundamental & clinical pharmacology 2012;26(4):495-502.
2012: Mohammad Ibrahim; Daiane Francine Meinerz; Cristina W Nogueira; Waseem Hassan; Gerlânia de Oliveira Leite; Joao B T Rocha
Ethanol-induced oxidative stress: the role of binaphthyl diselenide as a potent antioxidant.
Biological trace element research 2012;147(1-3):309-14.
2012: Cristiani F Bortolatto; Pietro M Chagas; Ethel A Wilhelm; Cristina W Nogueira
p-Chloro-diphenyl diselenide, an organoselenium compound, with antidepressant-like and memory enhancer actions in aging male rats.
Biogerontology 2012;13(3):237-49.
2012: Michael D Costa; Bibiana M Gai; Carmine I Acker; Ricardo Brandão; Ana Cristina G Souza; Cristina W Nogueira
Ebselen reduces hyperglycemia temporarily-induced by diazinon: a compound with insulin-mimetic properties.
Chemico-biological interactions 2012;197(2-3):80-6.
2012: Ethel A Wilhelm; Cristiani F Bortolatto; Cristina W Nogueira
p-Methoxyl-diphenyl diselenide protects against cisplatin-induced renal toxicity in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2012;50(5):1187-93.
2012: Mohammad Ibrahim; Cristina W Nogueira; Javed Anwar; Waseem Hassan; Joao Batista Teixeira Rocha
Fe(II) and sodium nitroprusside induce oxidative stress: a comparative study of diphenyl diselenide and diphenyl ditelluride with their napthyl analog.
Drug and chemical toxicology 2012;35(1):48-56.
2011: Cristina W Nogueira; João B T Rocha
Toxicology and pharmacology of selenium: emphasis on synthetic organoselenium compounds.
Archives of toxicology 2011;85(11):1313-59.
2011: Ricardo Brandão; Mayara L de Freitas; Marlon R Leite; Rafael N Moresco; Luziane P Bellé; Adalto Bianchini; Cristina W Nogueira
Diphenyl diselenide potentiates nephrotoxicity induced by mercuric chloride in mice.
Journal of applied toxicology : JAT 2011;31(8):773-82.
2011: C F Bortolatto; Cristiano R Jesse; L M Rambo; L R Ribeiro; S S Roman; Luiz Fernando Freire Royes; E A Wilhelm; Cristina W Nogueira
Protective effect of 2,2'-dithienyl diselenide on kainic acid-induced neurotoxicity in rat hippocampus.
Neuroscience 2011;193():300-9.
2011: Marina Prigol; César Augusto Brüning; Cristina W Nogueira; Gilson Zeni
The role of the glutathione system in seizures induced by diphenyl diselenide in rat pups.
Chemico-biological interactions 2011;193(1):65-70.
2011: Mohammad Ibrahim; Cristiane Luchese; Simone Pinton; Silvane S Roman; Waseem Hassan; Cristina W Nogueira; João B T Rocha
Involvement of catalase in the protective effect of binaphthyl diselenide against renal damage induced by glycerol.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 2011;63(4):331-5.
2011: João B T Rocha; Neusa M Heinzmann Bulow; Eduardo F M Correa; Cassiano Scholze; Cristina W Nogueira; N B V Barbosa
Dexmedetomidine protects blood δ-aminolevulinate dehydratase from inactivation caused by hyperoxygenation in total intravenous anesthesia.
Human & experimental toxicology 2011;30(4):289-95.
2011: Cristiano R Jesse; Ethel A Wilhelm; Cristiani F Bortolatto; Cristina W Nogueira
Role of different types of potassium channels and peroxisome proliferator-activated receptors γ in the antidepressant-like activity of bis selenide in the mouse tail suspension test.
Neuroscience letters 2011;490(3):205-8.
2011: Ricardo F Schumacher; Alisson R Rosário; Ana C G Souza; Carmine I Acker; Cristina W Nogueira; Gilson Zeni
The potential antioxidant activity of 2,3-dihydroselenophene, a prototype drug of 4-aryl-2,3-dihydroselenophenes.
Bioorganic & medicinal chemistry 2011;19(4):1418-25.
2011: Simone Pinton; Cristiane Luchese; Cristina W Nogueira
Comparison of the antioxidant properties and the toxicity of p,p'-dichlorodiphenyl ditelluride with the parent compound, diphenyl ditelluride.
Biological trace element research 2011;139(2):204-16.
2011: Ethel A Wilhelm; Cristiano R Jesse; Cristiani F Bortolatto; Cristina W Nogueira
(E)-2-benzylidene-4-phenyl-1,3-diselenole has antioxidant and hepatoprotective properties against oxidative damage induced by 2-nitropropane in rats.
Fundamental & clinical pharmacology 2011;25(1):80-90.
2011: Ricardo Brandão; Cristina W Nogueira
Inhibition of hepatic δ-aminolevulinate dehydratase activity induced by mercuric chloride is potentiated by N-acetylcysteine in vitro.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2011;49(1):305-8.
2010: Caroline Wagner; Jéssie H Sudati; Cristina W Nogueira; João B T Rocha
In vivo and in vitro inhibition of mice thioredoxin reductase by methylmercury.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2010;23(6):1171-7.
2010: Cristiano R Jesse; Ethel A Wilhelm; Cristina W Nogueira
Depression-like behavior and mechanical allodynia are reduced by bis selenide treatment in mice with chronic constriction injury: a comparison with fluoxetine, amitriptyline, and bupropion.
Psychopharmacology 2010;212(4):513-22.
2010: Ethel A Wilhelm; Cristiano R Jesse; Silvane Souza Roman; Cristiani F Bortolatto; Cristina W Nogueira
Anticonvulsant effect of (E)-2-benzylidene-4-phenyl-1,3-diselenole in a pilocarpine model in mice.
Life sciences 2010;87(19-22):620-7.
2010: Marina Prigol; Ethel A Wilhelm; Cristina W Nogueira; Gilson Zeni
Diphenyl diselenide-induced seizures in rat pups: possible interaction with GABAergic system.
Neurological research 2010;32(9):1002-8.
2010: Cristiane Luchese; Marina Prigol; Carmine Inês Acker; Cristina W Nogueira
Antinociceptive effect of butyl (2-phenylethynyl) selenide on formalin test in mice: Evidences for the involvement of serotonergic and adenosinergic systems.
European journal of pharmacology 2010;644(1-3):49-54.
2010: Cristiane Luchese; Cristina W Nogueira
Diphenyl diselenide in its selenol form has dehydroascorbate reductase and glutathione S-transferase-like activity dependent on the glutathione content.
The Journal of pharmacy and pharmacology 2010;62(9):1146-51.
2010: Ethel A Wilhelm; Cristiano R Jesse; Cristiani F Bortolatto; Nilda B V Barbosa; Cristina W Nogueira
Evidence of the involvement of K+ channels and PPARgamma receptors in the antidepressant-like activity of diphenyl diselenide in mice.
The Journal of pharmacy and pharmacology 2010;62(9):1121-7.
2010: Robson L Puntel; Daniel H Roos; Vanderlei Folmer; Cristina W Nogueira; Antonio Galina; Michael Aschner; João B T Rocha
Mitochondrial dysfunction induced by different organochalchogens is mediated by thiol oxidation and is not dependent of the classical mitochondrial permeability transition pore opening.
Toxicological sciences : an official journal of the Society of Toxicology 2010;117(1):133-43.
2010: Bibiana M Gay; Marina Prigol; André L Stein; Cristina W Nogueira
Antidepressant-like pharmacological profile of 3-(4-fluorophenylselenyl)-2,5-diphenylselenophene: Involvement of serotonergic system.
Neuropharmacology 2010;59(3):172-9.
2010: Ricardo Brandão; Renata de Oliveira; Cristina W Nogueira
Association between diphenyl diselenide and cadmium chloride attenuates the toxicity of both in tissues of mice in vitro.
Toxicology in vitro : an international journal published in association with BIBRA 2010;24(6):1736-42.
2010: Bibiana M Gay; Cristiane Luchese; Cristina W Nogueira; P Wendler; Alexandra Macedo; Alcindo A Dos Santos
Antioxidant effect of functionalized alkyl-organotellurides: a study in vitro.
Journal of enzyme inhibition and medicinal chemistry 2010;25(4):467-75.
2010: Cristiano R Jesse; Ethel A Wilhelm; Cristiani F Bortolatto; João B T Rocha; Cristina W Nogueira
Involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of bis selenide in the mouse tail suspension test.
European journal of pharmacology 2010;635(1-3):135-41.
2010: Mohammad Ibrahim; Marina Prigol; Waseem Hassan; Cristina W Nogueira; Joao B T Rocha
Protective effect of binaphthyl diselenide, a synthetic organoselenium compound, on 2-nitropropane-induced hepatotoxicity in rats.
Cell biochemistry and function 2010;28(4):258-65.
2010: Erico Silva Loreto; Liliane A Scheid; Cristina W Nogueira; Gilson Zeni; Janio M Santurio; Sydney Hartz Alves
Candida dubliniensis: epidemiology and phenotypic methods for identification.
Mycopathologia 2010;169(6):431-43.
2010: Cristiano R Jesse; Ethel A Wilhelm; Cristiani F Bortolatto; Cristina W Nogueira
Evidence for the involvement of the noradrenergic system, dopaminergic and imidazoline receptors in the antidepressant-like effect of tramadol in mice.
Pharmacology, biochemistry, and behavior 2010;95(3):344-50.
2010: Marina Prigol; Simone Pinton; Ricardo Schumacher; Cristina W Nogueira; Gilson Zeni
Convulsant action of diphenyl diselenide in rat pups: measurement and correlation with plasma, liver and brain levels of compound.
Archives of toxicology 2010;84(5):373-8.
2010: Cristiano R Jesse; Ethel A Wilhelm; Cristiani F Bortolatto; Cristina W Nogueira
Evidence for the involvement of the serotonergic 5-HT2A/C and 5-HT3 receptors in the antidepressant-like effect caused by oral administration of bis selenide in mice.
Progress in neuro-psychopharmacology & biological psychiatry 2010;34(2):294-302.
2010: Cristiani F Bortolatto; Cristiano R Jesse; Ethel A Wilhelm; Cristina W Nogueira
Involvement of potassium channels in the antidepressant-like effect of venlafaxine in mice.
Life sciences 2010;86(9-10):372-6.
2010: Caroline Wagner; Alessandra P Vargas; Daniel H Roos; Carla Porto; Marcelo Farina; Cristina W Nogueira; Michael Aschner; João B Rocha
Comparative study of quercetin and its two glycoside derivatives quercitrin and rutin against methylmercury (MeHg)-induced ROS production in rat brain slices.
Archives of toxicology 2010;84(2):89-97.
2010: Cristiano R Jesse; Cristina W Nogueira
Evidence for the involvement of glutamatergic and neurokinin 1 receptors in the antinociception elicited by tramadol in mice.
Pharmacology 2010;85(1):36-40.
2009: Juliana Trevisan da Rocha; Adriane Sperança; Cristina W Nogueira; Gilson Zeni
Hypolipidaemic activity of orally administered diphenyl diselenide in Triton WR-1339-induced hyperlipidaemia in mice.
The Journal of pharmacy and pharmacology 2009;61(12):1673-9.
2009: E A Wilhelm; Cristiano R Jesse; Cristina W Nogueira
Protective effect of p-methoxyl-diphenyl diselenide in lethal acute liver failure induced by lipopolysaccharide and D-galactosamine in mice.
Fundamental & clinical pharmacology 2009;23(6):727-34.
2009: Marina Prigol; César A Brüning; Benhur Godoi; Cristina W Nogueira; Gilson Zeni
m-Trifluoromethyl-diphenyl diselenide attenuates pentylenetetrazole-induced seizures in mice by inhibiting GABA uptake in cerebral cortex slices.
Pharmacological reports : PR 2009;61(6):1127-33.
2009: Ethel A Wilhelm; Cristiano R Jesse; Cristiani F Bortolatto; Cristina W Nogueira; Lucielli Savegnago
Antinociceptive and anti-allodynic effects of 3-alkynyl selenophene on different models of nociception in mice.
Pharmacology, biochemistry, and behavior 2009;93(4):419-25.
2009: Ricardo Brandão; Carmine I Acker; Marlon R Leite; Nilda B V Barbosa; Cristina W Nogueira
Diphenyl diselenide protects against glycerol-induced renal damage in rats.
Journal of applied toxicology : JAT 2009;29(7):612-8.
2009: Carmine Inês Acker; Ricardo Brandão; Alisson Rodrigues Rosário; Cristina W Nogueira
Antioxidant effect of alkynylselenoalcohol compounds on liver and brain of rats in vitro.
Environmental toxicology and pharmacology 2009;28(2):280-7.
2009: D B Santos; V P P Schiar; Marcio W Paixão; D F Meinerz; Cristina W Nogueira; Michael Aschner; João B T Rocha; N B V Barbosa
Hemolytic and genotoxic evaluation of organochalcogens in human blood cells in vitro.
Toxicology in vitro : an international journal published in association with BIBRA 2009;23(6):1195-204.
2009: G R Thomé; Cinthia M Mazzanti; Mushtaq Ahmed; Maísa Corrêa; Roselia M Spanevello; Paula Acosta Maldonado; Cristiane Luchese; Denise Cargnelutti; Vera M Morsch; M M M F Duarte; A M Fiorenza; Cristina W Nogueira; K S De Bona; Maria Beatriz Moretto; S C A Da Luz; Alexandre Mazzanti; Maria R C Schetinger
Activity of ectonucleotidases and adenosine deaminase in rats exposed to cigarette smoke.
Inhalation toxicology 2009;21(11):906-12.
2009: I J Kade; Cristina W Nogueira; J B T Rocha
Diphenyl diselenide and streptozotocin did not alter cerebral glutamatergic and cholinergic systems but modulate antioxidant status and sodium pump in diabetic rats.
Brain research 2009;1284():202-11.
2009: Ricardo Brandão; Lysandro P Borges; Cristina W Nogueira
Concomitant administration of sodium 2,3-dimercapto-1-propanesulphonate (DMPS) and diphenyl diselenide reduces effectiveness of DMPS in restoring damage induced by mercuric chloride in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2009;47(8):1771-8.
2009: Ethel A Wilhelm; Cristiano R Jesse; Silvane Souza Roman; Cristina W Nogueira; Lucielli Savegnago
Hepatoprotective effect of 3-alkynyl selenophene on acute liver injury induced by D-galactosamine and lipopolysaccharide.
Experimental and molecular pathology 2009;87(1):20-6.
2009: Eluza C Stangherlin; Cristiane Luchese; Ana Paula Ardais; Cristina W Nogueira
Passive smoke exposure induces oxidative damage in brains of rat pups: Protective role of diphenyl diselenide.
Inhalation toxicology 2009;21(10):868-74.
2009: I J Kade; Vanessa C Borges; Lucielli Savegnago; E O Ibukun; Gilson Zeni; Cristina W Nogueira; J B T Rocha
Effect of oral administration of diphenyl diselenide on antioxidant status, and activity of delta aminolevulinic acid dehydratase and isoforms of lactate dehydrogenase, in streptozotocin-induced diabetic rats.
Cell biology and toxicology 2009;25(4):415-24.
2009: Waseem Hassan; Mohammad Ibrahim; Cristina W Nogueira; Mushtaq Ahmed; Joao B T Rocha
Effects of acidosis and Fe (II) on lipid peroxidation in phospholipid extract: Comparative effect of diphenyl diselenide and ebselen.
Environmental toxicology and pharmacology 2009;28(1):152-4.
2009: Cristiane L Dalla Corte; Roselei Fachinetto; Robson Puntel; Caroline Wagner; Cristina W Nogueira; Félix A Soares; João B T Rocha
Chronic treatment with fluphenazine alters parameters of oxidative stress in liver and kidney of rats.
Basic & clinical pharmacology & toxicology 2009;105(1):51-7.
2009: Andreza Fabro de Bem; Rafael de Lima Portella; Elisângela Colpo; Marta Maria Medeiros Frescura Duarte; Andressa Frediane; Paulo Sergio Taube; Cristina W Nogueira; Marcelo Farina; Edson Luiz da Silva; João Batista Teixeira Rocha
Diphenyl diselenide decreases serum levels of total cholesterol and tissue oxidative stress in cholesterol-fed rabbits.
Basic & clinical pharmacology & toxicology 2009;105(1):17-23.
2009: Ethel A Wilhelm; Cristiano R Jesse; Cristiani F Bortolatto; Cristina W Nogueira; Lucielli Savegnago
Anticonvulsant and antioxidant effects of 3-alkynyl selenophene in 21-day-old rats on pilocarpine model of seizures.
Brain research bulletin 2009;79(5):281-7.
2009: Cristiano R Jesse; Ethel A Wilhelm; Nilda B V Barbosa; Cristina W Nogueira
Involvement of different types of potassium channels in the antidepressant-like effect of tramadol in the mouse forced swimming test.
European journal of pharmacology 2009;613(1-3):74-8.
2009: waseem Hassan; Mohammad Ibrahim; Cristina W Nogueira; Antonio L Braga; Anna Maria Deobald; Imdad Ullah Mohammadzai; Joao Batista Teixeira Rocha
Influence of pH on the reactivity of diphenyl ditelluride with thiols and anti-oxidant potential in rat brain.
Chemico-biological interactions 2009;180(1):47-53.
2009: Roberta A Oliveira; Lucielli Savegnago; Cristiano R Jesse; Paulo H Menezes; Gary A Molander; Cristina W Nogueira
Toxicological investigation and antinociceptive property of potassium thiophene-3-trifluoroborate.
Basic & clinical pharmacology & toxicology 2009;104(6):448-54.
2009: Marina Prigol; Cristiane Luchese; Cristina W Nogueira
Antioxidant effect of diphenyl diselenide on oxidative stress caused by acute physical exercise in skeletal muscle and lungs of mice.
Cell biochemistry and function 2009;27(4):216-22.
2009: Ethel A Wilhelm; Cristiano R Jesse; Marlon R Leite; Cristina W Nogueira
Studies on preventive effects of diphenyl diselenide on acetaminophen-induced hepatotoxicity in rats.
Pathophysiology : the official journal of the International Society for Pathophysiology / ISP 2009;16(1):31-7.
2009: D B Santos; V P P Schiar; M C P Ribeiro; R S Schwab; D F Meinerz; J Allebrandt; J B T Rocha; Cristina W Nogueira; Michael Aschner; N B V Barbosa
Genotoxicity of organoselenium compounds in human leukocytes in vitro.
Mutation research 2009;676(1-2):21-6.
2009: Carmine I Acker; Cristiane Luchese; Marina Prigol; Cristina W Nogueira
Antidepressant-like effect of diphenyl diselenide on rats exposed to malathion: involvement of Na+K+ ATPase activity.
Neuroscience letters 2009;455(3):168-72.
2009: Daniela A Barancelli; Anderson C Mantovani; Cristiano Jesse; Cristina W Nogueira; Gilson Zeni
Synthesis of natural polyacetylenes bearing furan rings.
Journal of natural products 2009;72(5):857-60.
2009: Cristiano R Jesse; Lucielli Savegnago; Cristina W Nogueira
Mechanisms involved in the antinociceptive and anti-inflammatory effects of bis selenide in mice.
The Journal of pharmacy and pharmacology 2009;61(5):623-30.
2009: Benhur Godoi; Adriane Sperança; Davi F Back; Ricardo Brandão; Cristina W Nogueira; Gilson Zeni
Synthesis of organochalcogen propargyl aryl ethers and their application in the electrophilic cyclization reaction: an efficient preparation of 3-halo-4-chalcogen-2H-benzopyrans.
The Journal of organic chemistry 2009;74(9):3469-77.
2009: Cristiano R Jesse; Ethel A Wilhelm; Cristiani F Bortolatto; Lucielli Savegnago; Cristina W Nogueira
Selective blockade of mGlu5 metabotropic glutamate receptors is hepatoprotective against fulminant hepatic failure induced by lipopolysaccharide and D-galactosamine in mice.
Journal of applied toxicology : JAT 2009;29(4):323-9.
2009: Ethel A Wilhelm; Cristiano R Jesse; Cristina W Nogueira; Lucielli Savegnago
Introduction of trifluoromethyl group into diphenyl diselenide molecule alters its toxicity and protective effect against damage induced by 2-nitropropane in rats.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 2009;61(3):197-203.
2009: Andressa Sausen de Freitas; Vinícius Rafael Funck; Mariana dos Santos Rotta; Denise Bohrer; Vanessa Mörschbächer; Robson Luiz Puntel; Cristina W Nogueira; Marcelo Farina; Michael Aschner; João B T Rocha
Diphenyl diselenide, a simple organoselenium compound, decreases methylmercury-induced cerebral, hepatic and renal oxidative stress and mercury deposition in adult mice.
Brain research bulletin 2009;79(1):77-84.
2009: Ana Cristina G Souza; Cristiane Luchese; Jose S Santos Neto; Cristina W Nogueira
Antioxidant effect of a novel class of telluroacetilene compounds: studies in vitro and in vivo.
Life sciences 2009;84(11-12):351-7.
2009: Flávia Manarin; Juliano A Roehrs; Rafaela Mozzaquatro Gay; Ricardo Brandão; Paulo H Menezes; Cristina W Nogueira; Gilson Zeni
Electrophilic cyclization of 2-chalcogenealkynylanisoles: versatile access to 2-chalcogen-benzo[b]furans.
The Journal of organic chemistry 2009;74(5):2153-62.
2009: Waseem Hassan; Mohammad Ibrahim; Cristina W Nogueira; Antonio L Braga; Imdad Ullah Mohammadzai; Paulo Sergio Taube; Joao Batista Teixeira Rocha
Enhancement of iron-catalyzed lipid peroxidation by acidosis in brain homogenate: comparative effect of diphenyl diselenide and ebselen.
Brain research 2009;1258():71-7.
2009: Lucielli Savegnago; Cristiano R Jesse; Cristina W Nogueira
Structural modifications into diphenyl diselenide molecule do not cause toxicity in mice.
Environmental toxicology and pharmacology 2009;27(2):271-6.
2009: Daniel H Roos; Robson Luiz Puntel; Matheus M Santos; Diogo O G Souza; Marcelo Farina; Cristina W Nogueira; Michael Aschner; Marilise E Burger; N B V Barbosa; João B T Rocha
Guanosine and synthetic organoselenium compounds modulate methylmercury-induced oxidative stress in rat brain cortical slices: involvement of oxidative stress and glutamatergic system.
Toxicology in vitro : an international journal published in association with BIBRA 2009;23(2):302-7.
2009: Cristiane Luchese; Simone Pinton; Cristina W Nogueira
Brain and lungs of rats are differently affected by cigarette smoke exposure: antioxidant effect of an organoselenium compound.
Pharmacological research : the official journal of the Italian Pharmacological Society 2009;59(3):194-201.
2009: Cristina W Nogueira; Lysandro Pinto Borges; Ana Cristina Guerra Souza
Oral administration of diphenyl diselenide potentiates hepatotoxicity induced by carbon tetrachloride in rats.
Journal of applied toxicology : JAT 2009;29(2):156-64.
2009: Cristiano R Jesse; João B T Rocha; Cristina W Nogueira; Lucielli Savegnago
Further analysis of the antinociceptive action caused by p-methoxyl-diphenyl diselenide in mice.
Pharmacology, biochemistry, and behavior 2009;91(4):573-80.
2009: I J Kade; Marcio W Paixão; Oscar E D Rodrigues; E O Ibukun; Antonio L Braga; Gilson Zeni; Cristina W Nogueira; João B T Rocha
Studies on the antioxidant effect and interaction of diphenyl diselenide and dicholesteroyl diselenide with hepatic delta-aminolevulinic acid dehydratase and isoforms of lactate dehydrogenase.
Toxicology in vitro : an international journal published in association with BIBRA 2009;23(1):14-20.
2009: Ricardo Brandão; Francielli W Santos; Renata Oliveira; Silvane Souza Roman; Cristina W Nogueira
Involvement of non-enzymatic antioxidant defenses in the protective effect of diphenyl diselenide on testicular damage induced by cadmium in mice.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2009;23(4):324-33.
2009: Cristiane Luchese; Eluza C Stangherlin; Bibiana M Gay; Cristina W Nogueira
Antioxidant effect of diphenyl diselenide on oxidative damage induced by smoke in rats: involvement of glutathione.
Ecotoxicology and environmental safety 2009;72(1):248-54.
2008: Cristiano R Jesse; Cristiani F Bortolatto; Lucielli Savegnago; João B T Rocha; Cristina W Nogueira
Involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of tramadol in the rat forced swimming test.
Progress in neuro-psychopharmacology & biological psychiatry 2008;32(8):1838-43.
2008: Nilda Berenice de Vargas Barbosa; Caroline Oliveira; Dioneia Araldi; Vanderlei Folmer; João Batista Teixeira Rocha; Cristina W Nogueira
Acute diphenyl diselenide treatment reduces hyperglycemia but does not change delta-aminolevulinate dehydratase activity in alloxan-induced diabetes in rats.
Biological & pharmaceutical bulletin 2008;31(12):2200-4.
2008: Lucielli Savegnago; Cristiano R Jesse; Adair R S Santos; Joâo B T Rocha; Cristina W Nogueira
Mechanisms involved in the antinociceptive effect caused by diphenyl diselenide in the formalin test.
The Journal of pharmacy and pharmacology 2008;60(12):1679-86.
2008: Simone N Weis; S S Roman; Cristina W Nogueira
Toxicity of 3'3-ditrifluormethyldiphenyl diselenide administered during intra-uterine development of rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2008;46(12):3640-5.
2008: Marina Prigol; Ethel A Wilhelm; Caroline C Schneider; Cristina W Nogueira
Protective effect of unsymmetrical dichalcogenide, a novel antioxidant agent, in vitro and an in vivo model of brain oxidative damage.
Chemico-biological interactions 2008;176(2-3):129-36.
2008: André L Stein; Diego Alves; Juliana T da Rocha; Cristina W Nogueira; Gilson Zeni
Copper iodide-catalyzed cyclization of (Z)-chalcogenoenynes.
Organic letters 2008;10(21):4983-6.
2008: Cristiano R Jesse; Lucielli Savegnago; Cristina W Nogueira
Effect of a metabotropic glutamate receptor 5 antagonist, MPEP, on the nociceptive response induced by intrathecal injection of excitatory aminoacids, substance P, bradykinin or cytokines in mice.
Pharmacology, biochemistry, and behavior 2008;90(4):608-13.
2008: Vanessa C Borges; Lucielli Savegnago; S Pinton; Cristiano R Jesse; Diego Alves; Cristina W Nogueira
Vinylic telluride derivatives as promising pharmacological compounds with low toxicity.
Journal of applied toxicology : JAT 2008;28(7):839-48.
2008: Cristiano R Jesse; Lucielli Savegnago; Cristina W Nogueira
Spinal mechanisms of antinociceptive effect caused by oral administration of bis-selenide in mice.
Brain research 2008;1231():25-33.
2008: Ricardo Brandão; Lysandro Pinto Borges; Renata de Oliveira; João B T Rocha; Cristina W Nogueira
Diphenyl diselenide protects against hematological and immunological alterations induced by mercury in mice.
Journal of biochemical and molecular toxicology 2008;22(5):311-9.
2008: R P Ineu; Maria E Pereira; M Aschner; Cristina W Nogueira; Gilson Zeni; J B T Rocha
Diphenyl diselenide reverses gastric lesions in rats: Involvement of oxidative stress.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2008;46(9):3023-9.
2008: Liane N Rotta; Daniel N Leszczinski; Ana M Brusque; Patrícia Pereira; Lucimar F S Brum; Cristina W Nogueira; Marcos E S Frizzo; Marcos L S Perry; Diogo O Souza
Effects of undernutrition on glutamatergic parameters in the cerebral cortex of young rats.
Physiology & behavior 2008;94(4):580-5.
2008: C L Dalla Corte; Roselei Fachinetto; D Colle; Romaiana P Pereira; Daiana Silva Avila; J G Villarinho; Caroline Wagner; Maria E Pereira; Cristina W Nogueira; Félix A Soares; João B T Rocha
Potentially adverse interactions between haloperidol and valerian.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2008;46(7):2369-75.
2008: Flavia Carla Meotti; Vanessa C Borges; Juliano Perottoni; Cristina W Nogueira
Toxicological evaluation of subchronic exposure to diphenyl diselenide in rats.
Journal of applied toxicology : JAT 2008;28(5):638-44.
2008: Marina Prigol; Ethel A Wilhelm; Eluza C Stangherlin; Daniela A Barancelli; Cristina W Nogueira; Gilson Zeni
Diphenyl diselenide-induced seizures in rat pups: possible interaction with glutamatergic system.
Neurochemical research 2008;33(6):996-1004.
2008: Daiana Silva Avila; Priscila Gubert; Aline Palma; Dirleise Colle; Diego Alves; Cristina W Nogueira; João B T Rocha; Félix A Soares
An organotellurium compound with antioxidant activity against excitotoxic agents without neurotoxic effects in brain of rats.
Brain research bulletin 2008;76(1-2):114-23.
2008: Lucielli Savegnago; Cristiano R Jesse; Cristina W Nogueira
Caffeine and a selective adenosine A(2B) receptor antagonist but not imidazoline receptor antagonists modulate antinociception induced by diphenyl diselenide in mice.
Neuroscience letters 2008;436(2):120-3.
2008: Ana P Ardais; Francielli W Santos; Cristina W Nogueira
Ebselen attenuates cadmium-induced testicular damage in mice.
Journal of applied toxicology : JAT 2008;28(3):322-8.
2008: Eluza Curte Stangherlin; Cristiane Luchese; Simone Pinton; João B T Rocha; Cristina W Nogueira
Sub-chronical exposure to diphenyl diselenide enhances acquisition and retention of spatial memory in rats.
Brain research 2008;1201():106-13.
2008: Cristiano R Jesse; Lucielli Savegnago; João B T Rocha; Cristina W Nogueira
Neuroprotective effect caused by MPEP, an antagonist of metabotropic glutamate receptor mGluR5, on seizures induced by pilocarpine in 21-day-old rats.
Brain research 2008;1198():197-203.
2008: Vanessa C Borges; Cristina W Nogueira
The role of thiol-reducing agents on modulation of glutamate binding induced by heavy metals in platelets.
Toxicology in vitro : an international journal published in association with BIBRA 2008;22(2):438-43.
2008: R M Golombieski; D A S Graichen; Lucinéia A Pivetta; Cristina W Nogueira; E L S Loreto; João B T Rocha
Diphenyl diselenide [(PhSe)2] inhibits Drosophila melanogaster delta-aminolevulinate dehydratase (delta-ALA-D) gene transcription and enzyme activity.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2008;147(2):198-204.
2008: Larissa G Pinto; Cristiano R Jesse; Cristina W Nogueira; Lucielli Savegnago
Evidence for the involvement of glutamatergic and GABAergic systems and protein kinase A pathway in the antinociceptive effect caused by p-methoxy-diphenyl diselenide in mice.
Pharmacology, biochemistry, and behavior 2008;88(4):487-96.
2008: Lucielli Savegnago; Cristiano R Jesse; Larissa G Pinto; João B T Rocha; Daniela Aline Barancelli; Cristina W Nogueira; Gilson Zeni
Diphenyl diselenide exerts antidepressant-like and anxiolytic-like effects in mice: involvement of L-arginine-nitric oxide-soluble guanylate cyclase pathway in its antidepressant-like action.
Pharmacology, biochemistry, and behavior 2008;88(4):418-26.
2008: Lysandro P Borges; Ricardo Brandão; Benhur Godoi; Cristina W Nogueira; Gilson Zeni
Oral administration of diphenyl diselenide protects against cadmium-induced liver damage in rats.
Chemico-biological interactions 2008;171(1):15-25.
2008: Rosane M Souza dos Santos; Andreza Fabro de Bem; Elisângela Colpo; Iara Bertoncello; Cristina W Nogueira; João B T Rocha
Plasmatic vitamin C in nontreated hepatitis C patients is negatively associated with aspartate aminotransferase.
Liver international : official journal of the International Association for the Study of the Liver 2008;28(1):54-60.
2008: N B V Barbosa; João B T Rocha; Júlio C M Soares; Daniele C Wondracek; Jamile F Gonçalves; Maria R C Schetinger; Cristina W Nogueira
Dietary diphenyl diselenide reduces the STZ-induced toxicity.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2008;46(1):186-94.
2008: Ige J Kade; Marcio W Paixão; Oscar E D Rodrigues; N B V Barbosa; Antonio L Braga; Daiana Avila; Cristina W Nogueira; João B T Rocha
Comparative studies on dicholesteroyl diselenide and diphenyl diselenide as antioxidant agents and their effect on the activities of Na+/K+ ATPase and delta-aminolevulinic acid dehydratase in the rat brain.
Neurochemical research 2008;33(1):167-78.
2007: Cristiano R Jesse; Lucielli Savegnago; Cristina W Nogueira
Role of nitric oxide/cyclic GMP/K(+) channel pathways in the antinociceptive effect caused by 2,3-bis(mesitylseleno)propenol.
Life sciences 2007;81(25-26):1694-702.
2007: Lucielli Savegnago; Cristiano R Jesse; Larissa G Pinto; João B T Rocha; Cristina W Nogueira
Diphenyl diselenide attenuates acute thermal hyperalgesia and persistent inflammatory and neuropathic pain behavior in mice.
Brain research 2007;1175():54-9.
2007: Márcia C Carvalho; Jeferson Luis Franco; Heloisa Ghizoni; Karoline Kobus; Evelise M Nazari; João B T Rocha; Cristina W Nogueira; Alcir L Dafre; Yara M R Müller; Marcelo Farina
Effects of 2,3-dimercapto-1-propanesulfonic acid (DMPS) on methylmercury-induced locomotor deficits and cerebellar toxicity in mice.
Toxicology 2007;239(3):195-203.
2007: Maria Beatriz Moretto; Bruna Boff; Jeferson Franco; Thaís Posser; Thisa Maite Roessler; Diogo O Souza; Cristina W Nogueira; Susana Wofchuk; João B T Rocha
(45)Ca(2+) influx in rat brain: effect of diorganylchalcogenides compounds.
Toxicological sciences : an official journal of the Society of Toxicology 2007;99(2):566-71.
2007: Cristiane Luchese; Ricardo Brandão; Renata de Oliveira; Cristina W Nogueira; Francielli W Santos
Efficacy of diphenyl diselenide against cerebral and pulmonary damage induced by cadmium in mice.
Toxicology letters 2007;173(3):181-90.
2007: Diego Alves; Cristiane Luchese; Cristina W Nogueira; Gilson Zeni
Electrophilic cyclization of (Z)-selenoenynes: synthesis and reactivity of 3-iodoselenophenes.
The Journal of organic chemistry 2007;72(18):6726-34.
2007: Lucielli Savegnago; Cristiano R Jesse; Larissa G Pinto; João B T Rocha; Cristina W Nogueira; Gilson Zeni
Monoaminergic agents modulate antidepressant-like effect caused by diphenyl diselenide in rats.
Progress in neuro-psychopharmacology & biological psychiatry 2007;31(6):1261-9.
2007: Lucielli Savegnago; Larissa G Pinto; Cristiano R Jesse; João B T Rocha; Cristina W Nogueira; Gilson Zeni
Spinal mechanisms of antinociceptive action caused by diphenyl diselenide.
Brain research 2007;1162():32-7.
2007: Vanessa C Borges; João B T Rocha; Lucielli Savegnago; Cristina W Nogueira
Repeated administration of diphenyl ditelluride induces hematological disorders in rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2007;45(8):1453-8.
2007: Andreza Fabro de Bem; Rafael de Lima Portella; Marcelo Farina; Juliano Perottoni; Marcio W Paixão; Cristina W Nogueira; João Batista Teixeira Rocha
Low toxicity of diphenyl diselenide in rabbits: a long-term study.
Basic & clinical pharmacology & toxicology 2007;101(1):47-55.
2007: Robson Luiz Puntel; Daniel Henrique Roos; Denise Grotto; Solange C Garcia; Cristina W Nogueira; João B T Rocha
Antioxidant properties of Krebs cycle intermediates against malonate pro-oxidant activity in vitro: a comparative study using the colorimetric method and HPLC analysis to determine malondialdehyde in rat brain homogenates.
Life sciences 2007;81(1):51-62.
2007: Vanessa C Borges; Francielli W Santos; João B T Rocha; Cristina W Nogueira
Heavy metals modulate glutamatergic system in human platelets.
Neurochemical research 2007;32(6):953-8.
2007: Maria Beatriz Moretto; Ana Paula Thomazi; Graça F R S Godinho; T M Roessler; Cristina W Nogueira; Diogo O Souza; Susana Wofchuk; João B T Rocha
Ebselen and diorganylchalcogenides decrease in vitro glutamate uptake by rat brain slices: prevention by DTT and GSH.
Toxicology in vitro : an international journal published in association with BIBRA 2007;21(4):639-45.
2007: Marina Prigol; Ethel A Wilhelm; Caroline C Schneider; João B T Rocha; Cristina W Nogueira; Gilson Zeni
Involvement of oxidative stress in seizures induced by diphenyl diselenide in rat pups.
Brain research 2007;1147():226-32.
2007: Alexandre M Favero; Simone N Weis; Eluza C Stangherlin; João B T Rocha; Cristina W Nogueira
Sub-chronic exposure of adult male rats to diphenyl ditelluride did not affect the development of their progeny.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2007;45(5):859-62.
2007: Daiana Silva Avila; Priscila Gubert; Cristiane Lenz Dalla Corte; Diego Alves; Cristina W Nogueira; João B T Rocha; Félix A Soares
A biochemical and toxicological study with diethyl 2-phenyl-2-tellurophenyl vinylphosphonate in a sub-chronic intraperitoneal treatment in mice.
Life sciences 2007;80(20):1865-72.
2007: Vanessa C Borges; Gabriele Dadalt; Lucielli Savegnago; Angélica V Moro; João B T Rocha; Cristina W Nogueira
1,1,2-Tris-organoselenide alkene derivatives, but not 1,2-bis-organoselenide alkene derivatives, inhibited delta-aminolevulinate dehydratase activity from human erythrocytic cells in vitro.
Toxicology in vitro : an international journal published in association with BIBRA 2007;21(3):387-91.
2007: Silvane Souza Roman; Alexandra Nava; Alexandre M Favero; Simone N Weis; Gilson Zeni; João B T Rocha; Cristina W Nogueira
Diphenyl ditelluride effect on embryo/fetal development in mice: interspecies differences.
Toxicology 2007;231(2-3):243-9.
2007: João B Souza; João B T Rocha; Cristina W Nogueira; Vanessa C Borges; Rosilene R Kaizer; Vera M Morsch; Valderi L Dressler; Ayrton F Martins; Erico M M Flores; Maria R C Schetinger
Delta-aminolevulinate dehydratase (delta-ALA-D) activity in diabetes and hypothyroidism.
Clinical biochemistry 2007;40(5-6):321-5.
2007: Cristiane Luchese; Eluza C Stangherlin; Ana P Ardais; Cristina W Nogueira; Francielli W Santos
Diphenyl diselenide prevents oxidative damage induced by cigarette smoke exposure in lung of rat pups.
Toxicology 2007;230(2-3):189-96.
2007: Simone N Weis; Alexandre M Favero; Eluza C Stangherlin; Flavia G Manarin; João B T Rocha; Cristina W Nogueira; Gilson Zeni
Repeated administration of diphenyl diselenide to pregnant rats induces adverse effects on embryonic/fetal development.
Reproductive toxicology (Elmsford, N.Y.) 2007;23(2):175-81.
2007: Viviane Patrícia P Schiar; Danúbia B Dos Santos; Diogo S Lüdtke; Fabrício Vargas; Marcio W Paixão; Cristina W Nogueira; Gilson Zeni; João B T Rocha
Screening of potentially toxic chalcogens in erythrocytes.
Toxicology in vitro : an international journal published in association with BIBRA 2007;21(1):139-45.
2007: Robson Luiz Puntel; Daniel Henrique Roos; Marcio W Paixão; Antonio L Braga; Gilson Zeni; Cristina W Nogueira; João B T Rocha
Oxalate modulates thiobarbituric acid reactive species (TBARS) production in supernatants of homogenates from rat brain, liver and kidney: effect of diphenyl diselenide and diphenyl ditelluride.
Chemico-biological interactions 2007;165(2):87-98.
2007: Cristiane Luchese; Gilson Zeni; João B T Rocha; Cristina W Nogueira; Francielli W Santos
Cadmium inhibits delta-aminolevulinate dehydratase from rat lung in vitro: interaction with chelating and antioxidant agents.
Chemico-biological interactions 2007;165(2):127-37.
2007: Lucielli Savegnago; Larissa G Pinto; Cristiano R Jesse; Diego Alves; João B T Rocha; Cristina W Nogueira; Gilson Zeni
Antinociceptive properties of diphenyl diselenide: evidences for the mechanism of action.
European journal of pharmacology 2007;555(2-3):129-38.
2007: Alexandre M Favero; Simone N Weis; Eluza C Stangherlin; Gilson Zeni; João B T Rocha; Cristina W Nogueira
Adult male rats sub-chronically exposed to diphenyl diselenide: Effects on their progeny.
Reproductive toxicology (Elmsford, N.Y.) 2007;23(1):119-23.
2006: Flavia Carla Meotti; Fabiana Cristina Missau; Juliano Ferreira; Moacir Geraldo Pizzolatti; Cristina Mizuzaki; Cristina W Nogueira; Adair R S Santos
Anti-allodynic property of flavonoid myricitrin in models of persistent inflammatory and neuropathic pain in mice.
Biochemical pharmacology 2006;72(12):1707-13.
2006: Thaís Posser; Maria Beatriz Moretto; Alcir L Dafre; Marcelo Farina; João Batista Teixeira da Rocha; Cristina W Nogueira; Gilson Zeni; Jovino Dos Santos Ferreira; Rodrigo B Leal; Jeferson Luis Franco
Antioxidant effect of diphenyl diselenide against sodium nitroprusside (SNP) induced lipid peroxidation in human platelets and erythrocyte membranes: an in vitro evaluation.
Chemico-biological interactions 2006;164(1-2):126-35.
2006: N B V Barbosa; João B T Rocha; Daniele C Wondracek; Juliano Perottoni; Gilson Zeni; Cristina W Nogueira
Diphenyl diselenide reduces temporarily hyperglycemia: possible relationship with oxidative stress.
Chemico-biological interactions 2006;163(3):230-8.
2006: Ricardo Brandão; Francielli W Santos; Marcelo Farina; Gilson Zeni; Denise Bohrer; João B T Rocha; Cristina W Nogueira
Antioxidants and metallothionein levels in mercury-treated mice.
Cell biology and toxicology 2006;22(6):429-38.
2006: Francielli W Santos; Dominguita L Graça; Gilson Zeni; João B T Rocha; Simone N Weis; Alexandre M Favero; Cristina W Nogueira
Sub-chronic administration of diphenyl diselenide potentiates cadmium-induced testicular damage in mice.
Reproductive toxicology (Elmsford, N.Y.) 2006;22(3):546-50.
2006: Lucielli Savegnago; Vanessa C Borges; Diego Alves; Cristiano R Jesse; João B T Rocha; Cristina W Nogueira
Evaluation of antioxidant activity and potential toxicity of 1-buthyltelurenyl-2-methylthioheptene.
Life sciences 2006;79(16):1546-52.
2006: Alexandre M Favero; Simone N Weis; Gilson Zeni; João B T Rocha; Cristina W Nogueira
Diphenyl diselenide changes behavior in female pups.
Neurotoxicology and teratology 2006;28(5):607-16.
2006: Caroline Wagner; Roselei Fachinetto; Cristiane Lenz Dalla Corte; Verônica B Brito; Diego Severo; Gilvan de Oliveira Costa Dias; Carla Porto; Cristina W Nogueira; João B T Rocha
Quercitrin, a glycoside form of quercetin, prevents lipid peroxidation in vitro.
Brain research 2006;1107(1):192-8.
2006: Ricardo Brandão; Francielli W Santos; Gilson Zeni; João B T Rocha; Cristina W Nogueira
DMPS and N-acetylcysteine induced renal toxicity in mice exposed to mercury.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2006;19(4):389-98.
2006: Andreza Fabro de Bem; Rafael de Lima Portella; Juliano Perottoni; Emilene Becker; Denise Bohrer; Marcio W Paixão; Cristina W Nogueira; Gilson Zeni; João B T Rocha
Changes in biochemical parameters in rabbits blood after oral exposure to diphenyl diselenide for long periods.
Chemico-biological interactions 2006;162(1):1-10.
2006: Daiana Silva de Avila; Marisa C Beque; Vanderlei Folmer; Antonio L Braga; Gilson Zeni; Cristina W Nogueira; Félix A Soares; João B T Rocha
Diethyl 2-phenyl-2 tellurophenyl vinylphosphonate: an organotellurium compound with low toxicity.
Toxicology 2006;224(1-2):100-7.
2006: Patrícia Prediger; Angélica V Moro; Cristina W Nogueira; Lucielli Savegnago; Paulo Henrique Menezes; João B T Rocha; Gilson Zeni
Palladium-catalyzed Suzuki cross-coupling of 2-haloselenophenes: synthesis of 2-arylselenophenes, 2,5-diarylselenophenes, and 2-arylselenophenyl ketones.
The Journal of organic chemistry 2006;71(10):3786-92.
2006: Eluza C Stangherlin; Alexandre M Favero; Simone N Weis; Gilson Zeni; João B T Rocha; Cristina W Nogueira
Assessment of reproductive toxicity in male rats following acute and sub-chronic exposures to diphenyl diselenide and diphenyl ditelluride.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2006;44(5):662-9.
2006: Eluza C Stangherlin; Alexandre M Favero; Gilson Zeni; João B T Rocha; Cristina W Nogueira
Exposure of mothers to diphenyl ditelluride during the suckling period changes behavioral tendencies in their offspring.
Brain research bulletin 2006;69(3):311-7.
2006: Hélio A Stefani; Carlindo B Oliveira; Roberta B Almeida; Claudio M P Pereira; Rodolpho C Braga; Rodrigo Cella; Vanessa C Borges; Lucielli Savegnago; Cristina W Nogueira
Dihydropyrimidin-(2H)-ones obtained by ultrasound irradiation: a new class of potential antioxidant agents.
European journal of medicinal chemistry 2006;41(4):513-8.
2006: Roselei Fachinetto; Lucinéia A Pivetta; Marcelo Farina; Romaiana P Pereira; Cristina W Nogueira; João B T Rocha
Effects of ethanol and diphenyl diselenide exposure on the activity of delta-aminolevulinate dehydratase from mouse liver and brain.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2006;44(4):588-94.
2006: Francielli W Santos; João B T Rocha; Cristina W Nogueira
2,3-Dimercaptopropanol, 2,3-dimercaptopropane-1-sulfonic acid and meso-2,3-dimercaptosuccinic acid increase lead-induced inhibition of delta-aminolevulinate dehydratase in vitro and ex vivo.
Toxicology in vitro : an international journal published in association with BIBRA 2006;20(3):317-23.
2006: Carlos A M do Nascimento; Cristina W Nogueira; Vanessa C Borges; João B T Rocha
Changes in [(3)H]-glutamate uptake into platelets from patients with bipolar I disorder.
Psychiatry research 2006;141(3):343-7.
2006: Lysandro P Borges; Cristina W Nogueira; Rodrigo B Panatieri; João B T Rocha; Gilson Zeni
Acute liver damage induced by 2-nitropropane in rats: effect of diphenyl diselenide on antioxidant defenses.
Chemico-biological interactions 2006;160(2):99-107.
2006: Olga Soares do Rêgo Barros; Cristina W Nogueira; Eluza C Stangherlin; Paulo Henrique Menezes; Gilson Zeni
Copper-promoted carbon-nitrogen bond formation with 2-iodo-selenophene and amides.
The Journal of organic chemistry 2006;71(4):1552-7.
2006: Verônica B Brito; Vanderlei Folmer; Gustavo O Puntel; Roselei Fachinetto; Júlio C M Soares; Gilson Zeni; Cristina W Nogueira; João B T Rocha
Diphenyl diselenide and 2,3-dimercaptopropanol increase the PTZ-induced chemical seizure and mortality in mice.
Brain research bulletin 2006;68(6):414-8.
2006: Lucielli Savegnago; Cristiano R Jesse; Angélica V Moro; Vanessa C Borges; Francielli W Santos; João B T Rocha; Cristina W Nogueira
Bis selenide alkene derivatives: A class of potential antioxidant and antinociceptive agents.
Pharmacology, biochemistry, and behavior 2006;83(2):221-9.
2006: Lucielli Savegnago; Marcio Trevisan; Diego Alves; Cristina W Nogueira; Joao Batista Teixeira Rocha; Gilson Zeni
Antisecretory and antiulcer effects of diphenyl diselenide.
Environmental toxicology and pharmacology 2006;21(1):86-92.
2005: Thissiane L Gonçalves; Fernando Erthal; Cristiane L D Corte; Liz G Müller; Clarice M Piovezan; Cristina W Nogueira; João B T Rocha
Involvement of oxidative stress in the pre-malignant and malignant states of cervical cancer in women.
Clinical biochemistry 2005;38(12):1071-5.
2005: Francielli W Santos; Gilson Zeni; João B T Rocha; Paulo Cícero do Nascimento; Marieli S Marques; Cristina W Nogueira
Efficacy of 2,3-dimercapto-1-propanesulfonic acid (DMPS) and diphenyl diselenide on cadmium induced testicular damage in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2005;43(12):1723-30.
2005: Vanessa C Borges; João B T Rocha; Cristina W Nogueira
Effect of diphenyl diselenide, diphenyl ditelluride and ebselen on cerebral Na(+), K(+)-ATPase activity in rats.
Toxicology 2005;215(3):191-7.
2005: Alexandre M Favero; Simone N Weis; Eluza C Stangherlin; Gilson Zeni; João B T Rocha; Cristina W Nogueira
Teratogenic effects of diphenyl diselenide in Wistar rats.
Reproductive toxicology (Elmsford, N.Y.) 2005;20(4):561-8.
2005: João B T Rocha; Leandro Ademar Lissner; Robson Luiz Puntel; Roselei Fachinetto; Tatiana Emanuelli; Cristina W Nogueira; Félix A Soares
Oxidation of delta-ALA-D and DTT mediated by ascorbic acid: modulation by buffers depends on free iron.
Biological & pharmaceutical bulletin 2005;28(8):1485-9.
2005: D Gabriel; Lucinéia A Pivetta; Vanderlei Folmer; Júlio C M Soares; G R Augusti; Cristina W Nogueira; Gilson Zeni; João B T Rocha
Human erythrocyte delta-aminolevulinate dehydratase inhibition by monosaccharides is not mediated by oxidation of enzyme sulfhydryl groups.
Cell biology international 2005;29(8):669-74.
2005: Lucielli Savegnago; Cristina W Nogueira; Roselei Fachinetto; João B T Rocha
Characterization of ATP and ADP hydrolysis activity in rat gastric mucosa.
Cell biology international 2005;29(7):559-66.
2005: Roselei Fachinetto; Marilise E Burger; Caroline Wagner; Daniele C Wondracek; Verônica B Brito; Cristina W Nogueira; Juliano Ferreira; João B T Rocha
High fat diet increases the incidence of orofacial dyskinesia and oxidative stress in specific brain regions of rats.
Pharmacology, biochemistry, and behavior 2005;81(3):585-92.
2005: Angélica V Moro; Cristina W Nogueira; N B V Barbosa; Paulo Henrique Menezes; João Batista Teixeira da Rocha; Gilson Zeni
Highly stereoselective one-pot procedure to prepare bis- and tris-chalcogenide alkenes via addition of disulfides and diselenides to terminal alkynes.
The Journal of organic chemistry 2005;70(13):5257-68.
2005: Lysandro P Borges; Vanessa C Borges; Angélica V Moro; Cristina W Nogueira; João B T Rocha; Gilson Zeni
Protective effect of diphenyl diselenide on acute liver damage induced by 2-nitropropane in rats.
Toxicology 2005;210(1):1-8.
2005: Francielli W Santos; C E Gonçales; João B T Rocha; Cristina W Nogueira
2,3-Dimercaptopropanol, 2,3-dimercaptopropane-1-sulfonic acid and meso-2,3-dimercaptosuccinic acid acute administration diferentially change biochemical parameters in mice.
Basic & clinical pharmacology & toxicology 2005;96(4):331-4.
2005: C E P Goncales; D Araldi; Rodrigo B Panatieri; João B T Rocha; Gilson Zeni; Cristina W Nogueira
Antinociceptive properties of acetylenic thiophene and furan derivatives: evidence for the mechanism of action.
Life sciences 2005;76(19):2221-34.
2005: Robson Luiz Puntel; Cristina W Nogueira; João B T Rocha
N-methyl-D-aspartate receptors are involved in the quinolinic acid, but not in the malonate pro-oxidative activity in vitro.
Neurochemical research 2005;30(3):417-24.
2005: Eluza C Stangherlin; Alexandre M Favero; Gilson Zeni; João B T Rocha; Cristina W Nogueira
Teratogenic vulnerability of Wistar rats to diphenyl ditelluride.
Toxicology 2005;207(2):231-9.
2005: Francielli W Santos; Gilson Zeni; João B T Rocha; Simone N Weis; Juliana M Fachinetto; Alexandre M Favero; Cristina W Nogueira
Diphenyl diselenide reverses cadmium-induced oxidative damage on mice tissues.
Chemico-biological interactions 2005;151(3):159-65.
2005: Fabricio B Zasso; Gilson Zeni; João B T Rocha; Dioneia Araldi; Carlos E P Goncales; Eduardo A C Jung; Cristina W Nogueira
On the mechanisms involved in antinociception induced by diphenyl diselenide.
Environmental toxicology and pharmacology 2005;19(2):283-9.
2005: J B T Rocha; L Siqueira; Gilson Zeni; D Gabriel; Cristina W Nogueira; Thaís Posser; Vanderlei Folmer
Ebselen and diphenyl diselenide change biochemical hepatic responses to overdosage with paracetamol.
Environmental toxicology and pharmacology 2005;19(2):255-61.
2005: Juliano Perottoni; Lucinéia A Pivetta; Vanderlei Folmer; Flavia Carla Meotti; Cristina W Nogueira; Gilson Zeni; João B T Rocha
Ebselen and diphenyl diselenide do not change the inhibitory effect of lead acetate on delta-aminolevulinate dehidratase.
Environmental toxicology and pharmacology 2005;19(2):239-48.
2005: Robson Luiz Puntel; Cristina W Nogueira; João B T Rocha
Krebs cycle intermediates modulate thiobarbituric acid reactive species (TBARS) production in rat brain in vitro.
Neurochemical research 2005;30(2):225-35.
2005: Vanderlei Folmer; Rodrigo Cordeiro Bolzan; Marcelo Farina; Gilson Zeni; Cristina W Nogueira; Tatiana Emanuelli; João B T Rocha
Mechanism of delta-aminolevulinate dehydratase inhibition by phenyl selenoacetylene involves its conversion to diphenyl diselenide.
Toxicology 2005;206(3):403-11.
2005: Ricardo Brandão; Fabiana S Lara; Letícia B Pagliosa; Félix A Soares; João B T Rocha; Cristina W Nogueira; Marcelo Farina
Hemolytic effects of sodium selenite and mercuric chloride in human blood.
Drug and chemical toxicology 2005;28(4):397-407.
2004: Cristina W Nogueira; Gilson Zeni; João B T Rocha
Organoselenium and organotellurium compounds: toxicology and pharmacology.
Chemical reviews 2004;104(12):6255-85.
2004: Vanderlei Folmer; Francielli W Santos; Lucielli Savegnago; Verônica B Brito; Cristina W Nogueira; João B T Rocha
High sucrose consumption potentiates the sub-acute cadmium effect on Na+/K+ -ATPase but not on delta-aminolevulinate dehydratase in mice.
Toxicology letters 2004;153(3):333-41.
2004: Vanderlei Folmer; Marcelo Farina; Evelise N Maciel; Cristina W Nogueira; Gilson Zeni; Tatiana Emanuelli; João B T Rocha
Methyl phenyl selenide causes heme biosynthesis impairment and its toxicity is not modified by dimethyl sulphoxide in vivo.
Drug and chemical toxicology 2004;27(4):331-40.
2004: Maria Beatriz Moretto; J Franco; Thaís Posser; Cristina W Nogueira; Gilson Zeni; João B T Rocha
Ebselen protects Ca2+ influx blockage but does not protect glutamate uptake inhibition caused by Hg2+.
Neurochemical research 2004;29(10):1801-6.
2004: Francielli W Santos; Tatiana Oro; Gilson Zeni; João B T Rocha; Paulo Cícero do Nascimento; Cristina W Nogueira
Cadmium induced testicular damage and its response to administration of succimer and diphenyl diselenide in mice.
Toxicology letters 2004;152(3):255-63.
2004: Vanessa C Borges; Cristina W Nogueira; Gilson Zeni; João B T Rocha
Organochalcogens affect the glutamatergic neurotransmission in human platelets.
Neurochemical research 2004;29(8):1505-9.
2004: Liane N Rotta; Félix A Soares; Cristina W Nogueira; Lucia Helena Martini; Marcos L S Perry; Diogo O Souza
Characterization of imido [8-(3)H] guanosine 5'-triphosphate binding sites to rat brain membranes.
Neurochemical research 2004;29(4):805-9.
2004: Gilson Zeni; Marcelo P Stracke; Cristina W Nogueira; Antonio L Braga; Paulo H Menezes; Hélio A Stefani
Hydroselenation of alkynes by lithium butylselenolate: an approach in the synthesis of vinylic selenides.
Organic letters 2004;6(7):1135-8.
2004: Gilson Zeni; Diego Alves; Jesus M Pena; Antonio L Braga; Hélio A Stefani; Cristina W Nogueira
Stereoselective preparation of conjugated E-enynes from E-vinylic tellurides and terminal alkynes via Sonogashira cross-coupling.
Organic & biomolecular chemistry 2004;2(6):803-5.
2004: Flavia Carla Meotti; Eluza C Stangherlin; Gilson Zeni; Cristina W Nogueira; João B T Rocha
Protective role of aryl and alkyl diselenides on lipid peroxidation.
Environmental research 2004;94(3):276-82.
2004: Cristina W Nogueira; Francielli W Santos; Félix A Soares; João B T Rocha
2,3-Dimercaptopropanol, 2,3-dimercaptopropane-1-sulfonic acid, and meso-2,3-dimercaptosuccinic acid inhibit delta-aminolevulinate dehydratase from human erythrocytes in vitro.
Environmental research 2004;94(3):254-61.
2003: Flavia Carla Meotti; Joao Batista T Rocha; Dagoberto O Silva; Gilson Zeni; Adair R S Dos Santos; Cristina W Nogueira
Thiophenes and furans derivatives: a new class of potential pharmacological agents.
Environmental toxicology and pharmacology 2003;15(1):37-44.
2003: Félix A Soares; Marcelo Farina; Francielli W Santos; Diogo Souza; João B T Rocha; Cristina W Nogueira
Interaction between metals and chelating agents affects glutamate binding on brain synaptic membranes.
Neurochemical research 2003;28(12):1859-65.
2003: Cristina W Nogueira; Vanessa C Borges; Gilson Zeni; João B T Rocha
Organochalcogens effects on delta-aminolevulinate dehydratase activity from human erythrocytic cells in vitro.
Toxicology 2003;191(2-3):169-78.
2003: Liane N Rotta; André P Schmidt; Tadeu Mello e Souza; Cristina W Nogueira; Karine B Souza; Ivan A Izquierdo; Marcos L S Perry; Diogo O Souza
Effects of undernutrition on glutamatergic parameters in rat brain.
Neurochemical research 2003;28(8):1181-6.
2003: Flavia Carla Meotti; Vanessa C Borges; Gilson Zeni; João B T Rocha; Cristina W Nogueira
Potential renal and hepatic toxicity of diphenyl diselenide, diphenyl ditelluride and Ebselen for rats and mice.
Toxicology letters 2003;143(1):9-16.
2003: Cristina W Nogueira; Félix A Soares; Paulo Cícero Nascimento; D Muller; João B T Rocha
2,3-Dimercaptopropane-1-sulfonic acid and meso-2,3-dimercaptosuccinic acid increase mercury- and cadmium-induced inhibition of delta-aminolevulinate dehydratase.
Toxicology 2003;184(2-3):85-95.
2003: Cristina W Nogueira; E B Quinhones; E A C Jung; Gilson Zeni; João B T Rocha
Anti-inflammatory and antinociceptive activity of diphenyl diselenide.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2003;52(2):56-63.
2003: Marilise E Burger; Audrei Alves; Luciano Callegari; Fernanda R Athayde; Cristina W Nogueira; Gilson Zeni; João B T Rocha
Ebselen attenuates reserpine-induced orofacial dyskinesia and oxidative stress in rat striatum.
Progress in neuro-psychopharmacology & biological psychiatry 2003;27(1):135-40.
2003: Cristina W Nogueira; Flavia Carla Meotti; E Curte; C Pilissão; Gilson Zeni; João B T Rocha
Investigations into the potential neurotoxicity induced by diselenides in mice and rats.
Toxicology 2003;183(1-3):29-37.
2003: Maria Beatriz Moretto; Janine I Rossato; Cristina W Nogueira; Gilson Zeni; João B T Rocha
Voltage-dependent ebselen and diorganochalcogenides inhibition of 45Ca2+ influx into brain synaptosomes.
Journal of biochemical and molecular toxicology 2003;17(3):154-60.
2002: Liane N Rotta; Cristina W Nogueira; Luciane da Silva; Félix A Soares; Marcos L S Perry; Diogo O Souza
Effect of undernutrition on GMP-PNP binding and adenylate cyclase activity from rat brain.
Cellular and molecular neurobiology 2002;22(3):365-72.
2002: Karla R de Oliveira; Liane N Rotta; Sandra C Valle; Diogo A Pilger; Cristina W Nogueira; Ana Maria Feoli; Elena Aida Bernard; Diogo O Souza; Marcos L S Perry
Ontogenetic study of the effects of energetic nutrients on amino acid metabolism of rat cerebral cortex.
Neurochemical research 2002;27(6):513-8.
2002: Marcelo Farina; N B V Barbosa; Cristina W Nogueira; Vanderlei Folmer; Gilson Zeni; L H Andrade; Antonio L Braga; João B T Rocha
Reaction of diphenyl diselenide with hydrogen peroxide and inhibition of delta-aminolevulinate dehydratase from rat liver and cucumber leaves.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 2002;35(6):623-31.
2002: Rodrigo Cordeiro Bolzan; Vanderlei Folmer; Marcelo Farina; Gilson Zeni; Cristina W Nogueira; João B T Rocha; Tatiana Emanuelli
Delta-aminolevulinate dehydratase inhibition by phenyl selenoacetylene: effect of reaction with hydrogen peroxide.
Pharmacology & toxicology 2002;90(4):214-9.
2002: Cristina W Nogueira; Liane N Rotta; Gilson Zeni; Diogo O Souza; João B T Rocha
Exposure to ebselen changes glutamate uptake and release by rat brain synaptosomes.
Neurochemical research 2002;27(4):283-8.
2001: Cristina W Nogueira; João B T Rocha; Diogo O Souza
Effect of dithiol chelating agents on [3H]MK-801 and [3H]glutamate binding to synaptic plasma membranes.
Neurochemical research 2001;26(12):1305-10.
2001: Cristina W Nogueira; Liane N Rotta; Marcos L S Perry; Diogo O Souza; João Batista Teixeira da Rocha
Diphenyl diselenide and diphenyl ditelluride affect the rat glutamatergic system in vitro and in vivo.
Brain research 2001;906(1-2):157-63.
2001: Cristina W Nogueira; L L Rotta; Rejane G Tavares; Diogo O Souza; João B T Rocha
BAL modulates glutamate transport in synaptosomes and synaptic vesicles from rat brain.
Neuroreport 2001;12(3):511-4.
2001: M C Jacques-Silva; Cristina W Nogueira; L C Broch; Erico M M Flores; João B T Rocha
Diphenyl diselenide and ascorbic acid changes deposition of selenium and ascorbic acid in liver and brain of mice.
Pharmacology & toxicology 2001;88(3):119-25.
2000: Cristina W Nogueira; Félix A Soares; Rodrigo Cordeiro Bolzan; M C Jacques-Silva; Diogo O Souza; João B T Rocha
Investigations into the mechanism of 2,3-dimercaptopropanol neurotoxicity.
Neurochemical research 2000;25(12):1553-8.