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Kees Nooter

Research Profile

Chemicals & Drugs

Physiology

Anatomy

Tumor Cells, Cultured

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TOP 3
A Felici; Walter J Loos; Jaap Verweij; I Cirillo; Peter de Bruijn; Kees Nooter; Ron H J Mathijssen; M J A de Jonge
A pharmacokinetic interaction study of docetaxel and cisplatin plus or minus 5-fluorouracil in the treatment of patients with recurrent or metastatic solid tumors.
Erin R Gardner; Herman Burger; Ron van Schaik; Allan T van Oosterom; Ernst A de Bruijn; Gunther Guetens; Hans Prenen; Floris A de Jong; Sharyn D Baker; Susan E Bates; William D Figg; Jaap Verweij; Alex Sparreboom; Kees Nooter
Association of enzyme and transporter genotypes with the pharmacokinetics of imatinib.
Jozien Helleman; Herman Burger; Irene H L Hamelers; Antonius W M Boersma; Anton I P M de Kroon; Gerrit Stoter; Kees Nooter
Impaired cisplatin influx in an A2780 mutant cell line: evidence for a putative, cis-configuration-specific, platinum influx transporter.

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All Publications

2006: A Felici; Walter J Loos; Jaap Verweij; I Cirillo; Peter de Bruijn; Kees Nooter; Ron H J Mathijssen; M J A de Jonge
A pharmacokinetic interaction study of docetaxel and cisplatin plus or minus 5-fluorouracil in the treatment of patients with recurrent or metastatic solid tumors.
Cancer chemotherapy and pharmacology 2006;58(5):673-80.
2006: Erin R Gardner; Herman Burger; Ron van Schaik; Allan T van Oosterom; Ernst A de Bruijn; Gunther Guetens; Hans Prenen; Floris A de Jong; Sharyn D Baker; Susan E Bates; William D Figg; Jaap Verweij; Alex Sparreboom; Kees Nooter
Association of enzyme and transporter genotypes with the pharmacokinetics of imatinib.
Clinical pharmacology and therapeutics 2006;80(2):192-201.
2006: Jozien Helleman; Herman Burger; Irene H L Hamelers; Antonius W M Boersma; Anton I P M de Kroon; Gerrit Stoter; Kees Nooter
Impaired cisplatin influx in an A2780 mutant cell line: evidence for a putative, cis-configuration-specific, platinum influx transporter.
Cancer biology & therapy 2006;5(8):943-9.
2006: Ton van Agthoven; Ton van Agthoven; Peter T Bosma; Kees Nooter; Lambert C J Dorssers
Functional screen for genes responsible for tamoxifen resistance in human breast cancer cells.
Molecular cancer research : MCR 2006;4(6):379-86.
2006: Jozien Helleman; maurice jansen; Paul Span; Iris L van Staveren; L F A G Massuger; Marion E Meijer-Van Gelder; Fred C G J Sweep; Patricia C Ewing; M E L van der Burg; Gerrit Stoter; Kees Nooter; Petronella Berns
Molecular profiling of platinum resistant ovarian cancer.
International journal of cancer. Journal international du cancer 2006;118(8):1963-71.
2006: Walter J Loos; Felix E de Jongh; Alex Sparreboom; Ronald de Wit; Desirée M van Boven-van Zomeren; Gerrit Stoter; Kees Nooter; Jaap Verweij
Evaluation of an alternate dosing strategy for cisplatin in patients with extreme body surface area values.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(10):1499-506.
2005: Herman Burger; Michael A Den Bakker; Johan M Kros; Hans Van Tol; Alex M de Bruin; Wolter Oosterhuis; Harry F G M van den Ingh; Erwin van der Harst; Hans P de Schipper; Erik A C Wiemer; Kees Nooter
Activating mutations in c-KIT and PDGFRalpha are exclusively found in gastrointestinal stromal tumors and not in other tumors overexpressing these imatinib mesylate target genes.
Cancer biology & therapy 2005;4(11):1270-4.
2005: Herman Burger; Hans Van Tol; Mariël Brok; Erik A C Wiemer; Ernst A de Bruijn; Gunther Guetens; Gert de Boeck; Alex Sparreboom; Jaap Verweij; Kees Nooter
Chronic imatinib mesylate exposure leads to reduced intracellular drug accumulation by induction of the ABCG2 (BCRP) and ABCB1 (MDR1) drug transport pumps.
Cancer biology & therapy 2005;4(7):747-52.
2005: Alex Sparreboom; Walter J Loos; Herman Burger; Tristan Sissung; Jaap Verweij; William D Figg; Kees Nooter; Hans Gelderblom
Effect of ABCG2 genotype on the oral bioavailability of topotecan.
Cancer biology & therapy 2005;4(6):650-8.
2005: Erin R Lepper; Kees Nooter; Jaap Verweij; Milin R Acharya; William D Figg; Alex Sparreboom
Mechanisms of resistance to anticancer drugs: the role of the polymorphic ABC transporters ABCB1 and ABCG2.
Pharmacogenomics 2005;6(2):115-38.
2004: Herman Burger; Kees Nooter
Pharmacokinetic resistance to imatinib mesylate: role of the ABC drug pumps ABCG2 (BCRP) and ABCB1 (MDR1) in the oral bioavailability of imatinib.
Cell cycle (Georgetown, Tex.) 2004;3(12):1502-5.
2004: Herman Burger; Hans Van Tol; Antonius W M Boersma; Mariël Brok; Erik A C Wiemer; Gerrit Stoter; Kees Nooter
Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump.
Blood 2004;104(9):2940-2.
2004: Paul W Schenk; hans stoop; Carsten Bokemeyer; Frank Mayer; Gerrit Stoter; J Wolter Oosterhuis; Erik A C Wiemer; Leendert H J Looijenga; Kees Nooter
Resistance to platinum-containing chemotherapy in testicular germ cell tumors is associated with downregulation of the protein kinase SRPK1.
Neoplasia (New York, N.Y.) 2004;6(4):297-301.
2003: Peter T Bosma; Simone J van Eert; Nicolaas G J Jaspers; Gerrit Stoter; Kees Nooter
Functional cloning of drug resistance genes from retroviral cDNA libraries.
Biochemical and biophysical research communications 2003;309(3):605-11.
2003: Paul W Schenk; Mariël Brok; Antonius W M Boersma; Jourica A Brandsma; Hans den Dulk; Herman Burger; Gerrit Stoter; Jaap Brouwer; Kees Nooter
Anticancer drug resistance induced by disruption of the Saccharomyces cerevisiae NPR2 gene: a novel component involved in cisplatin- and doxorubicin-provoked cell kill.
Molecular pharmacology 2003;64(2):259-68.
2003: Herman Burger; Michael A Den Bakker; Gerrit Stoter; Jaap Verweij; Kees Nooter
Lack of c-kit exon 11 activating mutations in c-KIT/CD117-positive SCLC tumour specimens.
European journal of cancer (Oxford, England : 1990) 2003;39(6):793-9.
2003: Walter J Loos; Hans Gelderblom; Jaap Verweij; Desirée M van Boven-van Zomeren; Kees Nooter; Gerrit Stoter; Alex Sparreboom
Red blood cells: a neglected compartment in topotecan pharmacokinetic analysis.
Anti-cancer drugs 2003;14(3):227-32.
2003: Herman Burger; John A Foekens; Maxime P Look; Marion E Meijer-Van Gelder; Jan G M Klijn; Erik A C Wiemer; Gerrit Stoter; Kees Nooter
RNA expression of breast cancer resistance protein, lung resistance-related protein, multidrug resistance-associated proteins 1 and 2, and multidrug resistance gene 1 in breast cancer: correlation with chemotherapeutic response.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(2):827-36.
2003: Carolien H Smorenburg; Alex Sparreboom; Marijke Bontenbal; Gerrit Stoter; Kees Nooter; Jaap Verweij
Randomized cross-over evaluation of body-surface area-based dosing versus flat-fixed dosing of paclitaxel.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(2):197-202.
2002: Walter J Loos; Janos Szebeni; Albert J ten Tije; Jaap Verweij; Desirée M van Zomeren; Kyu-nung Chung; Kees Nooter; Gerrit Stoter; Alex Sparreboom
Preclinical evaluation of alternative pharmaceutical delivery vehicles for paclitaxel.
Anti-cancer drugs 2002;13(7):767-75.
2002: Ron H J Mathijssen; Jaap Verweij; Walter J Loos; Peter de Bruijn; Kees Nooter; Alex Sparreboom
Irinotecan pharmacokinetics-pharmacodynamics: the clinical relevance of prolonged exposure to SN-38.
British journal of cancer 2002;87(2):144-50.
2002: Lia van Zuylen; Alex Sparreboom; Ate van der Gaast; Kees Nooter; Ferry A L M Eskens; E Brouwer; CJ Bol; R de Vries; Peter A Palmer; Jaap Verweij
Disposition of docetaxel in the presence of P-glycoprotein inhibition by intravenous administration of R101933.
European journal of cancer (Oxford, England : 1990) 2002;38(8):1090-9.
2002: Hans Gelderblom; Jaap Verweij; Desirée M van Zomeren; Dirk Buijs; Linda Ouwens; Kees Nooter; Gerrit Stoter; Alex Sparreboom
Influence of Cremophor El on the bioavailability of intraperitoneal paclitaxel.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(4):1237-41.
2002: Walter J Loos; Jaap Verweij; Diederik F S Kehrer; Peter de Bruijn; Franciscus M H de Groot; Marta Hamilton; Kees Nooter; Gerrit Stoter; Alex Sparreboom
Structural identification and biological activity of 7-methyl-10,11-ethylenedioxy-20(S)-camptothecin, a photodegradant of lurtotecan.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(3):856-62.
2002: Paul W Schenk; Antonius W M Boersma; Mariël Brok; Herman Burger; Gerrit Stoter; Kees Nooter
Inactivation of the Saccharomyces cerevisiae SKY1 gene induces a specific modification of the yeast anticancer drug sensitivity profile accompanied by a mutator phenotype.
Molecular pharmacology 2002;61(3):659-66.
2002: Walter J Loos; Desirée M van Zomeren; Hans Gelderblom; Jaap Verweij; Kees Nooter; Gerrit Stoter; Alex Sparreboom
Determination of topotecan in human whole blood and unwashed erythrocytes by high-performance liquid chromatography.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2002;766(1):99-105.
2002: Ron H J Mathijssen; Jaap Verweij; M J A de Jonge; Kees Nooter; Gerrit Stoter; Alex Sparreboom
Impact of body-size measures on irinotecan clearance: alternative dosing recommendations.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(1):81-7.
2002: Hans Gelderblom; Walter J Loos; Jaap Verweij; M E L van der Burg; M J A de Jonge; E Brouwer; Kees Nooter; Gerrit Stoter; Alex Sparreboom
Modulation of cisplatin pharmacodynamics by Cremophor EL: experimental and clinical studies.
European journal of cancer (Oxford, England : 1990) 2002;38(1):205-13.
2001: Paul W Schenk; Antonius W M Boersma; J A Brandsma; Hans den Dulk; Herman Burger; Gerrit Stoter; J Brouwer; Kees Nooter
SKY1 is involved in cisplatin-induced cell kill in Saccharomyces cerevisiae, and inactivation of its human homologue, SRPK1, induces cisplatin resistance in a human ovarian carcinoma cell line.
Cancer research 2001;61(19):6982-6.
2001: Felix E de Jongh; Jaap Verweij; Walter J Loos; Ronald de Wit; M J A de Jonge; A S T Planting; Kees Nooter; Gerrit Stoter; Alex Sparreboom
Body-surface area-based dosing does not increase accuracy of predicting cisplatin exposure.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(17):3733-9.
2001: Hans Gelderblom; Jaap Verweij; Kees Nooter; Alex Sparreboom
Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation.
European journal of cancer (Oxford, England : 1990) 2001;37(13):1590-8.
2001: Ron H J Mathijssen; RJ van Alphen; Jaap Verweij; Walter J Loos; Kees Nooter; Gerrit Stoter; Alex Sparreboom
Clinical pharmacokinetics and metabolism of irinotecan (CPT-11).
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(8):2182-94.
2001: Lia van Zuylen; M O Karlsson; Jaap Verweij; E Brouwer; Peter de Bruijn; Kees Nooter; Gerrit Stoter; Alex Sparreboom
Pharmacokinetic modeling of paclitaxel encapsulation in Cremophor EL micelles.
Cancer chemotherapy and pharmacology 2001;47(4):309-18.
2000: Lia van Zuylen; Kees Nooter; Alex Sparreboom; Jaap Verweij
Development of multidrug-resistance convertors: sense or nonsense?
Investigational new drugs 2000;18(3):205-20.
2000: Lia van Zuylen; Jaap Verweij; Kees Nooter; E Brouwer; Gerrit Stoter; Alex Sparreboom
Role of intestinal P-glycoprotein in the plasma and fecal disposition of docetaxel in humans.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(7):2598-603.
2000: H Burger; A Capello; Paul W Schenk; Gerrit Stoter; Jaap Brouwer; Kees Nooter
A genome-wide screening in Saccharomyces cerevisiae for genes that confer resistance to the anticancer agent cisplatin.
Biochemical and biophysical research communications 2000;269(3):767-74.
2000: Walter J Loos; Diederik F S Kehrer; E Brouwer; Jaap Verweij; Peter de Bruijn; Marta Hamilton; S Gill; Kees Nooter; Gerrit Stoter; Alex Sparreboom
Liposomal lurtotecan (NX211): determination of total drug levels in human plasma and urine by reversed-phase high-performance liquid chromatography.
Journal of chromatography. B, Biomedical sciences and applications 2000;738(1):155-63.
1999: Walter J Loos; Peter de Bruijn; Lia van Zuylen; Jaap Verweij; Kees Nooter; Gerrit Stoter; Alex Sparreboom
Determination of 5-fluorouracil in microvolumes of human plasma by solvent extraction and high-performance liquid chromatography.
Journal of chromatography. B, Biomedical sciences and applications 1999;735(2):293-7.
1999: Alex Sparreboom; Walter J Loos; Kees Nooter; Gerrit Stoter; Jaap Verweij
Liquid chromatographic analysis and preliminary pharmacokinetics of methotrexate in cancer patients co-treated with docetaxel.
Journal of chromatography. B, Biomedical sciences and applications 1999;735(1):111-9.
1999: Hans Gelderblom; Jaap Verweij; E Brouwer; M Pillay; Peter de Bruijn; Kees Nooter; Gerrit Stoter; Alex Sparreboom
Disposition of [G-(3)H]paclitaxel and cremophor EL in a patient with severely impaired renal function.
Drug metabolism and disposition: the biological fate of chemicals 1999;27(11):1300-5.
1999: Alex Sparreboom; A S T Planting; Roxanne C Jewell; M E L van der Burg; Ate van der Gaast; Peter de Bruijn; Walter J Loos; Kees Nooter; L H Chandler; Elaine M Paul; Paul Wissel; Jaap Verweij
Clinical pharmacokinetics of doxorubicin in combination with GF120918, a potent inhibitor of MDR1 P-glycoprotein.
Anti-cancer drugs 1999;10(8):719-28.
1999: Alex Sparreboom; M J A de Jonge; C J Punt; Walter J Loos; Kees Nooter; Gerrit Stoter; M G Porro; Jaap Verweij
Prediction of the systemic exposure to oral 9-amino-20(S)-camptothecin using single-sample analysis.
Drug metabolism and disposition: the biological fate of chemicals 1999;27(7):816-20.
1999: Herman Burger; Kees Nooter; Antonius W M Boersma; KE van Wingerden; Leendert H J Looijenga; A G Jochemsen; Gerrit Stoter
Distinct p53-independent apoptotic cell death signalling pathways in testicular germ cell tumour cell lines.
International journal of cancer. Journal international du cancer 1999;81(4):620-8.
1999: Peter de Bruijn; M J de Jonge; J Verweij; W J Loos; Kees Nooter; Gerrit Stoter; Alex Sparreboom
Femtomole quantitation of 7-ethyl-10-hydroxycamptothecine (SN-38) in plasma samples by reversed-phase high-performance liquid chromatography.
Analytical biochemistry 1999;269(1):174-8.
1999: Alex Sparreboom; Lia van Zuylen; E Brouwer; Walter J Loos; Peter de Bruijn; Hans Gelderblom; M Pillay; Kees Nooter; Gerrit Stoter; Jaap Verweij
Cremophor EL-mediated alteration of paclitaxel distribution in human blood: clinical pharmacokinetic implications.
Cancer research 1999;59(7):1454-7.
1999: Peter de Bruijn; Jaap Verweij; Walter J Loos; HJ Kolker; A S T Planting; Kees Nooter; Gerrit Stoter; Alex Sparreboom
Determination of doxorubicin and doxorubicinol in plasma of cancer patients by high-performance liquid chromatography.
Analytical biochemistry 1999;266(2):216-21.
1999: Ron H J Mathijssen; RJ van Alphen; M J A de Jonge; Jaap Verweij; Peter de Bruijn; Walter J Loos; Kees Nooter; Laurent Vernillet; Gerrit Stoter; Alex Sparreboom
Sparse-data set analysis for irinotecan and SN-38 pharmacokinetics in cancer patients co-treated with cisplatin.
Anti-cancer drugs 1999;10(1):9-16.
1998: Alex Sparreboom; M J A de Jonge; Peter de Bruijn; E Brouwer; Kees Nooter; Walter J Loos; RJ van Alphen; Ron H J Mathijssen; Gerrit Stoter; Jaap Verweij
Irinotecan (CPT-11) metabolism and disposition in cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(11):2747-54.
1998: Alex Sparreboom; Peter de Bruijn; M J A de Jonge; Walter J Loos; Gerrit Stoter; Jaap Verweij; Kees Nooter
Liquid chromatographic determination of irinotecan and three major metabolites in human plasma, urine and feces.
Journal of chromatography. B, Biomedical sciences and applications 1998;712(1-2):225-35.
1998: Alex Sparreboom; Jaap Verweij; M E L van der Burg; Walter J Loos; E Brouwer; L Viganò; A Locatelli; AI de Vos; Kees Nooter; Gerrit Stoter; Luca Gianni
Disposition of Cremophor EL in humans limits the potential for modulation of the multidrug resistance phenotype in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(8):1937-42.
1998: Alex Sparreboom; M J A de Jonge; Cornelis J A Punt; Kees Nooter; Walter J Loos; M G Porro; Jaap Verweij
Pharmacokinetics and bioavailability of oral 9-aminocamptothecin capsules in adult patients with solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(8):1915-9.
1998: E Brouwer; Jaap Verweij; B Hauns; Walter J Loos; Kees Nooter; Klaus Mross; Gerrit Stoter; Alex Sparreboom
Linearized colorimetric assay for cremophor EL: application to pharmacokinetics after 1-hour paclitaxel infusions.
Analytical biochemistry 1998;261(2):198-202.
1998: J Ma; M Maliepaard; Kees Nooter; Walter J Loos; HJ Kolker; Jaap Verweij; Gerrit Stoter; J H M Schellens
Reduced cellular accumulation of topotecan: a novel mechanism of resistance in a human ovarian cancer cell line.
British journal of cancer 1998;77(10):1645-52.
1998: Herman Burger; Kees Nooter; Antonius W M Boersma; CJ Kortland; Gerrit Stoter
Expression of p53, Bcl-2 and Bax in cisplatin-induced apoptosis in testicular germ cell tumour cell lines.
British journal of cancer 1998;77(10):1562-7.
1998: Herman Burger; Kees Nooter; Antonius W M Boersma; CJ Kortland; A P van den Berg; Gerrit Stoter
Expression of p53, p21/WAF/CIP, Bcl-2, Bax, Bcl-x, and Bak in radiation-induced apoptosis in testicular germ cell tumor lines.
International journal of radiation oncology, biology, physics 1998;41(2):415-24.
1998: Alex Sparreboom; Peter de Bruijn; Kees Nooter; Walter J Loos; Gerrit Stoter; Jaap Verweij
Determination of paclitaxel in human plasma using single solvent extraction prior to isocratic reversed-phase high-performance liquid chromatography with ultraviolet detection.
Journal of chromatography. B, Biomedical sciences and applications 1998;705(1):159-64.
1998: Alex Sparreboom; Walter J Loos; Jaap Verweij; AI de Vos; M E L van der Burg; Gerrit Stoter; Kees Nooter
Quantitation of Cremophor EL in human plasma samples using a colorimetric dye-binding microassay.
Analytical biochemistry 1998;255(2):171-5.
1998: Kees Nooter; T Kok; F T Bosman; KE van Wingerden; Gerrit Stoter
Expression of the multidrug resistance protein (MRP) in squamous cell carcinoma of the oesophagus and response to pre-operative chemotherapy.
European journal of cancer (Oxford, England : 1990) 1998;34(1):81-6.
1998: J Ma; M Maliepaard; Kees Nooter; Antonius W M Boersma; Jaap Verweij; Gerrit Stoter; J H M Schellens
Synergistic cytotoxicity of cisplatin and topotecan or SN-38 in a panel of eight solid-tumor cell lines in vitro.
Cancer chemotherapy and pharmacology 1998;41(4):307-16.
1997: Herman Burger; Kees Nooter; Antonius W M Boersma; CJ Kortland; Gerrit Stoter
Lack of correlation between cisplatin-induced apoptosis, p53 status and expression of Bcl-2 family proteins in testicular germ cell tumour cell lines.
International journal of cancer. Journal international du cancer 1997;73(4):592-9.
1997: AI de Vos; Kees Nooter; Jaap Verweij; Walter J Loos; E Brouwer; Peter de Bruijn; E J Ruijgrok; M E L van der Burg; Gerrit Stoter; Alex Sparreboom
Differential modulation of cisplatin accumulation in leukocytes and tumor cell lines by the paclitaxel vehicle Cremophor EL.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1997;8(11):1145-50.
1997: T C Kok; Kees Nooter; SP Tjong-A-Hung; H L Smits; Jan ter Schegget
No evidence of known types of human papillomavirus in squamous cell cancer of the oesophagus in a low-risk area. Rotterdam Oesophageal Tumour Study Group.
European journal of cancer (Oxford, England : 1990) 1997;33(11):1865-8.
1997: Peter de Bruijn; Jaap Verweij; Walter J Loos; Kees Nooter; Gerrit Stoter; Alex Sparreboom
Determination of irinotecan (CPT-11) and its active metabolite SN-38 in human plasma by reversed-phase high-performance liquid chromatography with fluorescence detection.
Journal of chromatography. B, Biomedical sciences and applications 1997;698(1-2):277-85.
1997: Walter J Loos; Alex Sparreboom; Jaap Verweij; Kees Nooter; Gerrit Stoter; J H M Schellens
Determination of the lactone and lactone plus carboxylate forms of 9-aminocamptothecin in human plasma by sensitive high-performance liquid chromatography with fluorescence detection.
Journal of chromatography. B, Biomedical sciences and applications 1997;694(2):435-41.
1997: Walter J Loos; Jaap Verweij; Kees Nooter; Gerrit Stoter; Alex Sparreboom
Sensitive determination of docetaxel in human plasma by liquid-liquid extraction and reversed-phase high-performance liquid chromatography.
Journal of chromatography. B, Biomedical sciences and applications 1997;693(2):437-41.
1997: Antonius W M Boersma; Kees Nooter; Herman Burger; CJ Kortland; Gerrit Stoter
Bax upregulation is an early event in cisplatin-induced apoptosis in human testicular germ-cell tumor cell line NT2, as quantitated by flow cytometry.
Cytometry 1997;27(3):275-82.
1997: Kees Nooter; G Brutel de la Riviere; Maxime P Look; KE van Wingerden; SC Henzen-Logmans; Rik J Scheper; M J Flens; J G Klijn; Gerrit Stoter; John A Foekens
The prognostic significance of expression of the multidrug resistance-associated protein (MRP) in primary breast cancer.
British journal of cancer 1997;76(4):486-93.
1996: Antonius W M Boersma; Kees Nooter; R G Oostrum; Gerrit Stoter
Quantification of apoptotic cells with fluorescein isothiocyanate-labeled annexin V in chinese hamster ovary cell cultures treated with cisplatin.
Cytometry 1996;24(2):123-30.
1996: R A Olie; Antonius W M Boersma; M C Dekker; Kees Nooter; Leendert H J Looijenga; J Wolter Oosterhuis
Apoptosis of human seminoma cells upon disruption of their microenvironment.
British journal of cancer 1996;73(9):1031-6.
1996: Kees Nooter; Herman Burger; Gerrit Stoter
Multidrug resistance-associated protein (MRP) in haematological malignancies.
Leukemia & lymphoma 1996;20(5-6):381-7.
1996: Kees Nooter; F T Bosman; Herman Burger; K E van Wingerden; Marcel J Flens; Rik J Scheper; R G Oostrum; Antonius W M Boersma; Ate van der Gaast; Gerrit Stoter
Expression of the multidrug resistance-associated protein (MRP) gene in primary non-small-cell lung cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1996;7(1):75-81.
1995: Kees Nooter; A M Westerman; Marcel J Flens; G J Zaman; Rik J Scheper; K E van Wingerden; Herman Burger; R Oostrum; T Boersma; Pieter Sonneveld
Expression of the multidrug resistance-associated protein (MRP) gene in human cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(11):1301-10.
1995: P A te Boekhorst; Bob Löwenberg; J van Kapel; Kees Nooter; Pieter Sonneveld
Multidrug resistant cells with high proliferative capacity determine response to therapy in acute myeloid leukemia.
Leukemia 1995;9(6):1025-31.
1995: Kees Nooter; Antonius W M Boersma; R G Oostrum; Herman Burger; A G Jochemsen; G Stoter
Constitutive expression of the c-H-ras oncogene inhibits doxorubicin-induced apoptosis and promotes cell survival in a rhabdomyosarcoma cell line.
British journal of cancer 1995;71(3):556-61.
1994: Herman Burger; Kees Nooter; Pieter Sonneveld; K E Van Wingerden; G J Zaman; G Stoter
High expression of the multidrug resistance-associated protein (MRP) in chronic and prolymphocytic leukaemia.
British journal of haematology 1994;88(2):348-56.
1994: Herman Burger; Kees Nooter; G J Zaman; Pieter Sonneveld; K E van Wingerden; R G Oostrum; G Stoter
Expression of the multidrug resistance-associated protein (MRP) in acute and chronic leukemias.
Leukemia 1994;8(6):990-7.
1994: Kees Nooter; H Herweijer; R R Jonker; Ger van den Engh
On-line flow cytometry: a versatile method for kinetic measurements.
Methods in cell biology 1994;41():509-25.
1993: P A te Boekhorst; K de Leeuw; M Schoester; S Wittebol; Kees Nooter; Anne Hagemeijer; Bob Löwenberg; Pieter Sonneveld
Predominance of functional multidrug resistance (MDR-1) phenotype in CD34+ acute myeloid leukemia cells.
Blood 1993;82(10):3157-62.
1993: Pieter Sonneveld; Jacques J M van Dongen; Anne Hagemeijer; Kirsten van Lom; Kees Nooter; M Schoester; H J Adriaansen; T Tsuruo; K de Leeuw
High expression of the multidrug resistance P-glycoprotein in high-risk myelodysplasia is associated with immature phenotype.
Leukemia 1993;7(7):963-9.
1992: Pieter Sonneveld; Kees Nooter; J T Burghouts; H Herweijer; H J Adriaansen; Jacques J M van Dongen
High expression of the mdr3 multidrug-resistance gene in advanced-stage chronic lymphocytic leukemia.
Blood 1992;79(6):1496-500.
1991: Jaap Verweij; H Herweijer; R Oosterom; M E L van der Burg; A S T Planting; C Seynaeve; G Stoter; Kees Nooter
A phase II study of epidoxorubicin in colorectal cancer and the use of cyclosporin-A in an attempt to reverse multidrug resistance.
British journal of cancer 1991;64(2):361-4.
1991: Kees Nooter; H Herweijer
Multidrug resistance (mdr) genes in human cancer.
British journal of cancer 1991;63(5):663-9.
1991: C J Rodenburg; Kees Nooter; H Herweijer; C Seynaeve; R Oosterom; G Stoter; Jaap Verweij
Phase II study of combining vinblastine and cyclosporin-A to circumvent multidrug resistance in renal cell cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1991;2(4):305-6.
1991: H Herweijer; Kees Nooter; A Beishuizen; Pieter Sonneveld; R G Oostrum; A L Hesseling-Janssen; Jacques J M van Dongen
Expression of mdr1 and mdr3 multidrug-resistance genes in hairy cell leukaemia.
European journal of cancer (Oxford, England : 1990) 1991;27(3):297-8.
1990: H Herweijer; Pieter Sonneveld; F Baas; Kees Nooter
Expression of mdr1 and mdr3 multidrug-resistance genes in human acute and chronic leukemias and association with stimulation of drug accumulation by cyclosporine.
Journal of the National Cancer Institute 1990;82(13):1133-40.
1990: Kees Nooter; Pieter Sonneveld; A Janssen; R Oostrum; T Boersma; H Herweijer; D Valerio; A Hagemeijer; F Baas
Expression of the mdr3 gene in prolymphocytic leukemia: association with cyclosporin-A-induced increase in drug accumulation.
International journal of cancer. Journal international du cancer 1990;45(4):626-31.
1990: M H Silbermann; B vd Vecht; G Stoter; Kees Nooter; J Verweij
Combination therapy of ACNU and ifosfamide in tumor bearing mice with M2661 breast cancer, B16 malignant melanoma or C38 colon cancer.
European journal of cancer (Oxford, England : 1990) 1990;26(3):321-5.
1990: Kees Nooter; Pieter Sonneveld; R Oostrum; H Herweijer; T Hagenbeek; D Valerio
Overexpression of the mdr1 gene in blast cells from patients with acute myelocytic leukemia is associated with decreased anthracycline accumulation that can be restored by cyclosporin-A.
International journal of cancer. Journal international du cancer 1990;45(2):263-8.
1990: Kees Nooter; H Herweijer; R Jonker; Ger van den Engh
On-line flow cytometry: a versatile method for kinetic measurements.
Methods in cell biology 1990;33():631-45.
1989: M H Silbermann; A W Boersma; A L Janssen; R J Scheper; H Herweijer; Kees Nooter
Effects of cyclosporin A and verapamil on the intracellular daunorubicin accumulation in Chinese hamster ovary cells with increasing levels of drug-resistance.
International journal of cancer. Journal international du cancer 1989;44(4):722-6.
1989: H Herweijer; Ger van den Engh; Kees Nooter
A rapid and sensitive flow cytometric method for the detection of multidrug-resistant cells.
Cytometry 1989;10(4):463-8.
1989: Kees Nooter; R Oostrum; R Jonker; Herman van Dekken; W Stokdijk; Ger van den Engh
Effect of cyclosporin A on daunorubicin accumulation in multidrug-resistant P388 leukemia cells measured by real-time flow cytometry.
Cancer chemotherapy and pharmacology 1989;23(5):296-300.
1987: Kees Nooter; R Oostrum; J Deurloo
Effects of verapamil on the pharmacokinetics of daunomycin in the rat.
Cancer chemotherapy and pharmacology 1987;20(2):176-8.
1986: Kees Nooter; Pieter Sonneveld; Anton Martens; A Hagenbeek; F Schultz
Tissue distribution and myelotoxicity of daunomycin in the rat: rapid bolus injection vs continuous infusion.
European journal of cancer & clinical oncology 1986;22(7):801-6.
1985: Kees Nooter; Pieter Sonneveld; Anton Martens
Differences in the pharmacokinetics of daunomycin in normal and leukemic rats.
Cancer research 1985;45(9):4020-5.
1984: Kees Nooter; Pieter Sonneveld; J Deurloo; R Oostrum; F Schultz; Anton Martens; A Hagenbeek
Repeated daunomycin administration in rats. Pharmacokinetics and bone marrow toxicity.
Cancer chemotherapy and pharmacology 1984;12(3):187-9.