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Henri Nordlund

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Juha A E Määttä; Yael Eisenberg-Domovich; Henri R Nordlund; Ruchama Hayouka; Markku S Kulomaa; Oded Livnah; Vesa P Hytönen
Chimeric avidin shows stability against harsh chemical conditions--biochemical analysis and 3D structure.
Tiina A Riihimäki; Kristiina Takkinen; Andreas Ebner; Soili Hiltunen; Peter Hinterdorfer; Markku S Kulomaa; Juha A E Määttä; Henri R Nordlund; Martina Rangl; Vesa P Hytönen
Modification of the loops in the ligand-binding site turns avidin into a steroid-binding protein.
Juha A E Määttä; Tomi T Airenne; Henri R Nordlund; Janne Jänis; Tiina A Paldanius; Pirjo Vainiotalo; Mark S Johnson; Markku S Kulomaa; Vesa P Hytönen
Rational modification of ligand-binding preference of avidin by circular permutation and mutagenesis.

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All Publications

2011: Juha A E Määttä; Yael Eisenberg-Domovich; Henri R Nordlund; Ruchama Hayouka; Markku S Kulomaa; Oded Livnah; Vesa P Hytönen
Chimeric avidin shows stability against harsh chemical conditions--biochemical analysis and 3D structure.
Biotechnology and bioengineering 2011;108(3):481-90.
2011: Tiina A Riihimäki; Kristiina Takkinen; Andreas Ebner; Soili Hiltunen; Peter Hinterdorfer; Markku S Kulomaa; Juha A E Määttä; Henri R Nordlund; Martina Rangl; Vesa P Hytönen
Modification of the loops in the ligand-binding site turns avidin into a steroid-binding protein.
BMC biotechnology 2011;11():64.
2008: Juha A E Määttä; Tomi T Airenne; Henri R Nordlund; Janne Jänis; Tiina A Paldanius; Pirjo Vainiotalo; Mark S Johnson; Markku S Kulomaa; Vesa P Hytönen
Rational modification of ligand-binding preference of avidin by circular permutation and mutagenesis.
Chembiochem : a European journal of chemical biology 2008;9(7):1124-35.
2007: Satu H Helppolainen; Kirsi P Nurminen; Juha A E Määttä; Katrin K Halling; J Peter Slotte; Tuulia Huhtala; Timo Liimatainen; Seppo Ylä-Herttuala; Kari J Airenne; Ale Närvänen; Janne Jänis; Pirjo Vainiotalo; Jarkko Valjakka; Markku S Kulomaa; Henri R Nordlund
Rhizavidin from Rhizobium etli: the first natural dimer in the avidin protein family.
The Biochemical journal 2007;405(3):397-405.
2007: Olli H Laitinen; Henri R Nordlund; Vesa P Hytönen; Markku S Kulomaa
Brave new (strept)avidins in biotechnology.
Trends in biotechnology 2007;25(6):269-77.
2007: Vesa P Hytönen; Juha A E Määttä; Einari Niskanen; Juhani Huuskonen; Kaisa J Helttunen; Katrin K Halling; Henri R Nordlund; Kari Rissanen; Mark S Johnson; Tiina A Salminen; Markku S Kulomaa; Olli H Laitinen; Tomi T Airenne
Structure and characterization of a novel chicken biotin-binding protein A (BBP-A).
BMC structural biology 2007;7():8.
2006: Olli H Laitinen; Vesa P Hytönen; Henri R Nordlund; Markku S Kulomaa
Genetically engineered avidins and streptavidins.
Cellular and molecular life sciences : CMLS 2006;63(24):2992-3017.
2006: Vesa P Hytönen; Jarno Hörhä; Tomi T Airenne; Einari Niskanen; Kaisa J Helttunen; Mark S Johnson; Tiina A Salminen; Markku S Kulomaa; Henri R Nordlund
Controlling quaternary structure assembly: subunit interface engineering and crystal structure of dual chain avidin.
Journal of molecular biology 2006;359(5):1352-63.
2005: Henri R Nordlund; Vesa P Hytönen; Jarno Hörhä; Juha A E Määttä; Daniel J White; Katrin K Halling; Eevaleena J Porkka; J Peter Slotte; Olli H Laitinen; Markku S Kulomaa
Tetravalent single-chain avidin: from subunits to protein domains via circularly permuted avidins.
The Biochemical journal 2005;392(Pt 3):485-91.
2005: Vesa P Hytönen; Henri R Nordlund; Jarno Hörhä; Thomas Nyholm; David E Hyre; Tuomas Kulomaa; Eevaleena J Porkka; Ari T Marttila; Patrick S Stayton; Olli H Laitinen; Markku S Kulomaa
Dual-affinity avidin molecules.
Proteins 2005;61(3):597-607.
2005: Henri R Nordlund; Olli H Laitinen; Sanna T H Uotila; Minna Kulmala; Nisse Kalkkinen; Markku S Kulomaa
Production of Hev b5 as a fluorescent biotin-binding tripartite fusion protein in insect cells.
Biochemical and biophysical research communications 2005;336(1):232-8.
2005: Henri R Nordlund; Vesa P Hytönen; Olli H Laitinen; Markku S Kulomaa
Novel avidin-like protein from a root nodule symbiotic bacterium, Bradyrhizobium japonicum.
The Journal of biological chemistry 2005;280(14):13250-5.
2005: Vesa P Hytönen; Juha A E Määttä; Thomas Nyholm; Oded Livnah; Yael Eisenberg-Domovich; David E Hyre; Henri R Nordlund; Jarno Hörhä; Einari Niskanen; Tiina Paldanius; Tuomas Kulomaa; Eevaleena J Porkka; Patrick S Stayton; Olli H Laitinen; Markku S Kulomaa
Design and construction of highly stable, protease-resistant chimeric avidins.
The Journal of biological chemistry 2005;280(11):10228-33.
2005: Einari Niskanen; Vesa P Hytönen; Alessandro Grapputo; Henri R Nordlund; Markku S Kulomaa; Olli H Laitinen
Chicken genome analysis reveals novel genes encoding biotin-binding proteins related to avidin family.
BMC genomics 2005;6():41.
2005: Olli H Laitinen; Kari J Airenne; Vesa P Hytönen; Erik Peltomaa; Anssi J Mähönen; Thomas Wirth; Miia M Lind; Kari A Mäkelä; Pyry I Toivanen; Diana Schenkwein; Tommi Heikura; Henri R Nordlund; Markku S Kulomaa; Seppo Ylä-Herttuala
A multipurpose vector system for the screening of libraries in bacteria, insect and mammalian cells and expression in vivo.
Nucleic acids research 2005;33(4):e42.
2004: Vesa P Hytönen; Olli H Laitinen; Tomi T Airenne; Heidi Kidron; Niko J Meltola; Eevaleena J Porkka; Jarno Hörhä; Tiina Paldanius; Juha A E Määttä; Henri R Nordlund; Mark S Johnson; Tiina A Salminen; Kari J Airenne; Seppo Ylä-Herttuala; Markku S Kulomaa
Efficient production of active chicken avidin using a bacterial signal peptide in Escherichia coli.
The Biochemical journal 2004;384(Pt 2):385-90.
2004: Henri R Nordlund; Olli H Laitinen; Vesa P Hytönen; Sanna T H Uotila; Eevaleena J Porkka; Markku S Kulomaa
Construction of a dual chain pseudotetrameric chicken avidin by combining two circularly permuted avidins.
The Journal of biological chemistry 2004;279(35):36715-9.
2004: Vesa P Hytönen; Thomas Nyholm; Olli Pentikäinen; Jonne Vaarno; Eevaleena J Porkka; Henri R Nordlund; Mark S Johnson; J Peter Slotte; Olli H Laitinen; Markku S Kulomaa
Chicken avidin-related protein 4/5 shows superior thermal stability when compared with avidin while retaining high affinity to biotin.
The Journal of biological chemistry 2004;279(10):9337-43.
2003: Henri R Nordlund; Vesa P Hytönen; Olli H Laitinen; Sanna T H Uotila; Einari Niskanen; Janne Savolainen; Eevaleena J Porkka; Markku S Kulomaa
Introduction of histidine residues into avidin subunit interfaces allows pH-dependent regulation of quaternary structure and biotin binding.
FEBS letters 2003;555(3):449-54.
2003: Sari P Kukkonen; Kari J Airenne; Varpu Marjomäki; Olli H Laitinen; Pauliina Lehtolainen; Pasi Kankaanpää; Anssi J Mähönen; Jani Räty; Henri R Nordlund; Christian Oker-Blom; Markku S Kulomaa; Seppo Ylä-Herttuala
Baculovirus capsid display: a novel tool for transduction imaging.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;8(5):853-62.
2003: Vesa P Hytönen; Olli H Laitinen; Alessandro Grapputo; Anu Kettunen; Janne Savolainen; Nisse Kalkkinen; Ari T Marttila; Henri R Nordlund; Thomas Nyholm; Giovanni Paganelli; Markku S Kulomaa
Characterization of poultry egg-white avidins and their potential as a tool in pretargeting cancer treatment.
The Biochemical journal 2003;372(Pt 1):219-25.
2003: Olli H Laitinen; Henri R Nordlund; Vesa P Hytönen; Sanna T H Uotila; Ari T Marttila; Janne Savolainen; Kari J Airenne; Oded Livnah; Edward A Bayer; Meir Wilchek; Markku S Kulomaa
Rational design of an active avidin monomer.
The Journal of biological chemistry 2003;278(6):4010-4.
2003: Henri R Nordlund; Olli H Laitinen; Sanna T H Uotila; Thomas Nyholm; Vesa P Hytönen; J Peter Slotte; Markku S Kulomaa
Enhancing the thermal stability of avidin. Introduction of disulfide bridges between subunit interfaces.
The Journal of biological chemistry 2003;278(4):2479-83.
2002: Olli H Laitinen; Vesa P Hytönen; Mervi K Ahlroth; Olli Pentikäinen; Ciara Gallagher; Henri R Nordlund; Vladimir Ovod; Ari T Marttila; Eevaleena J Porkka; Sanna Heino; Mark S Johnson; Kari J Airenne; Markku S Kulomaa
Chicken avidin-related proteins show altered biotin-binding and physico-chemical properties as compared with avidin.
The Biochemical journal 2002;363(Pt 3):609-17.